Open access peer-reviewed Edited Volume

Restricted Growth

Clinical, Genetic and Molecular Aspects

Restricted growth conditions are a group of genetic disorders with primary effect on growth (short stature); it is very heterogeneous and comprises two important categories: skeletal dysplasia and different genetic syndromes with primary effect on growth. It could also be caused by a medical condition. The book contains chapters regarding different aspects of the study of restricted growth that are divided into three broad sections. Section I: Defining Restricted Growth, Section II: Genetics and Diagnosis of Restricted Growth, and Section III: Signaling Pathways and Molecular Mechanisms of Restricted Growth. The book presents comprehensive reviews of each topic written by experts in the field. It will be the most valuable tool for physicians and life science researchers and students. We hope that the book will motivate discussion and research in this important health problem, setting the path for better therapeutic approaches.

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Restricted GrowthClinical, Genetic and Molecular AspectsEdited by Maria del Carmen Cardenas-Aguayo

Published: October 12th 2016

DOI: 10.5772/61620

ISBN: 978-953-51-2695-9

Print ISBN: 978-953-51-2694-2

eBook (PDF) ISBN: 978-953-51-7315-1

Copyright year: 2016

Books open for chapter submissions

7809 Total Chapter Downloads

2 Crossref Citations

5 Web of Science Citations

4 Dimensions Citations


Open access peer-reviewed

1. Growth Hormone Axis in Skeletal Dysplasias

By Stefano Stagi, Annachiara Azzali, Luisa La Spina, Matteo Della Monica, Perla Scalini and Maurizio de Martino


Open access peer-reviewed

2. Growth Hormone Deficiency: Diagnosis and Therapy in Children

By Mauro Bozzola and Cristina Meazza


Open access peer-reviewed

3. Genetic Determinants of Short Stature

By Diana Miclea


Open access peer-reviewed

4. Molecular Defects and Cellular Dysfunctions in Restricted Growth Conditions

By Monica Mottes and Patricia Marie-Jeanne Lievens


Open access peer-reviewed

5. Growth Hormone Receptor Signaling Pathways and its Negative Regulation by SOCS2

By Leandro Fernández-Pérez, Amilcar Flores-Morales, Borja Guerra, Juan C. Díaz-Chico and Diego Iglesias-Gato


Open access peer-reviewed

6. Mannose-6-Phosphate/Insulin-Like Growth Factor 2 Receptor (M6P/IGF2-R) in Growth and Disease: A Review

By Guy Joseph Lemamy, Bénédicte Ndeboko, Serge Thierry Omouessi and Justine Mouecoucou


Edited Volume and chapters are indexed in

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