Open access peer-reviewed Edited Volume

Mitochondrial Diseases

Edited by Eylem Taskin

Nigde Omer Halisdemir University


Yusuf Sevgiler

Adiyaman University

Mitochondria are crucial organelles for any cell type. Mitochondria take responsibility for not only energy production but also regulation of cell death, also called apoptosis; calcium storage; and heat production. Therefore, mitochondrial disease is implicated in the mode of action of many harmful factors for cells such as drugs and environmental contaminants, dysfunction of the oxygen transport system, malnutrition, intense exercise, and genetic variations. This book presents up-to-date knowledge about mitochondrial disease and its complex relation to some diseases such as cardiac failure, cancer, and Alzheimer's and Parkinson's diseases. This book will, therefore, be essential for readers who are interested in life sciences, especially in medicine.

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Mitochondrial DiseasesEdited by Eylem Taskin

Published: August 29th 2018

DOI: 10.5772/67963

ISBN: 978-1-78923-675-0

Print ISBN: 978-1-78923-674-3

eBook (PDF) ISBN: 978-1-83881-272-0

Copyright year: 2018

Books open for chapter submissions

18400 Total Chapter Downloads

20 Crossref Citations

10 Web of Science Citations

42 Dimensions Citations


Open access peer-reviewed

1. Mitochondria and Metabolism in Right Heart Failure

By Danielle R. Bruns and Lori A. Walker


Open access peer-reviewed

2. Mitochondria and Heart Disease

By Shaunrick Stoll, Christiana Leimena and Hongyu Qiu


Open access peer-reviewed

3. Interplay Between Mitochondrial Proteins and Age-Associated Risk of Cardiovascular Diseases

By Zuzana Tatarkova, Martin Kolisek, Ivana Pilchova, Peter Racay and Peter Kaplan


Open access peer-reviewed

4. Differential Effect of Atpenin A5 on ROS Production from Wild- Type Mitochondrial Complex II in Human Cancer Cells and Normal Cells

By Madhavi P. Paranagama and Kiyoshi Kita


Open access peer-reviewed

5. A New Insight into the Development of Novel Anti-Cancer Drugs that Improve the Expression of Mitochondrial Function-Associated Genes

By Fumiaki Uchiumi, Jun Arakawa, Yutaka Takihara, Motohiro Akui, Hiroshi Hamada and Sei-ichi Tanuma


Open access peer-reviewed

6. Mitochondria at the Base of Neuronal Innate Immunity in Alzheimer’s and Parkinson’s Diseases

By A. Raquel Esteves, Diana F. Silva, Daniel Santos, Emanuel Candeias, Filipa Filipe and Sandra M. Cardoso


Open access peer-reviewed

7. Protein Kinases and Regulation of Mitochondrial Function in Ischemia/Reperfusion Injury

By Grażyna Nowak


Open access peer-reviewed

8. Mitochondrial Trafficking by Prohibitin-Kinesin-Myosin- Cadherin Complex in the Eye

By Srinivas R. Sripathi, Weilue He, Johnpaul Offor, Diana R. Gutsaeva and Wan Jin Jahng


Open access peer-reviewed

9. 18 kDa Translocator Protein in Mitochondria-Related Pathology: The Case of Traumatic Brain Injury

By Nahum Rosenberg, Nasra Yasin, Leo Veenman, Orit Rosenberg, Abraham Weizman and Moshe Gavish


Open access peer-reviewed

10. Hereditary Disorders and Human Mutations of Iron-Sulfur Assembly Genes

By Namik Kaya, Zuhair Al-Hassnan, Maha Abdulrahim, Mazhor Aldosary and Dilek Colak


Open access peer-reviewed

11. Nuclear Encoded Mitochondrial Proteins in Metabolite Transport and Oxidation Pathway Connecting Metabolism of Nutrients

By Janka Vašková, Jozef Firment and Ladislav Vaško


Open access peer-reviewed

12. Pyrethroid Insecticides as the Mitochondrial Dysfunction Inducers

By Celal Guven, Yusuf Sevgiler and Eylem Taskin


Open access peer-reviewed

13. Mitochondrial Dysfunction Associated with Doxorubicin

By Celal Guven, Yusuf Sevgiler and Eylem Taskin


Open access peer-reviewed

14. Ethanol Consumption Affects Neuronal Function: Role of the Mitochondria

By Cheril Tapia-Rojas, María José Pérez, Claudia Jara, Erick H. Vergara and Rodrigo A. Quintanilla


Open access peer-reviewed

15. Mitochondrial Oxidative Stress and Calcium-Dependent Permeability Transition are Key Players in the Mechanisms of Statins-Associated Side Effects

By Estela N.B. Busanello, Ana C. Marques, Estela Lorza-Gil, Helena C.F. de Oliveira and Anibal E. Vercesi


Open access peer-reviewed

16. Ketamine Induces Neuroapoptosis in Stem Cell–Derived Developing Human Neurons Possibly through Intracellular Calcium/Mitochondria/microRNA Signaling Pathway

By Danielle Twaroski, Yasheng Yan, Congshan Jiang, Sarah Logan, Zeljko J. Bosnjak and Xiaowen Bai


Open access peer-reviewed

17. Modulation of Mitochondria During Viral Infections

By Latif Reshi, Hao-Ven Wang and Jiann-Ruey Hong


Open access peer-reviewed

18. Estrogen and Mitochondrial Function in Disease

By Ved P. Mooga, C. Roger White and Samantha Giordano-Mooga


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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