Open access peer-reviewed Edited Volume

Mitochondria and Brain Disorders

Edited by Stavros Baloyannis

Aristotle University of Thessaloniki

The mitochondrion is a unique and ubiquitous organelle that contains its own genome, encoding essential proteins that are major components of the respiratory chain and energy production system. Mitochondria play a dominant role in the life and function of eukaryotic cells including neurons and glia, as their survival and activity depend upon mitochondrial energy production and supply. Besides energy production, mitochondria also play a vital role in calcium homeostasis and may induce apoptosis by excitotoxicity. Mitochondrial dysfunction is related to common neurological diseases, such as Parkinson's disease, Alzheimer's disease, Friedreich's ataxia, Huntington's disease, and Multiple Sclerosis. An efficient treatment of mitochondrial dysfunction would open new horizons in the therapeutic perspectives of a substantial number of inflammatory and degenerative neurological disorders.

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Mitochondria and Brain DisordersEdited by Stavros Baloyannis

Published: March 11th 2020

DOI: 10.5772/intechopen.77668

ISBN: 978-1-78985-532-6

Print ISBN: 978-1-78985-531-9

eBook (PDF) ISBN: 978-1-78985-653-8

Copyright year: 2020

Books open for chapter submissions

722 Total Chapter Downloads

chaptersDownloads

Open access peer-reviewed

1. Introductory Chapter: Mitochondrial Alterations and Neurological Disorders

By Stavros J. Baloyannis

31

Open access peer-reviewed

2. Pathology Associated with Hormones of Adrenal Cortex

By Lovelesh K. Nigam, Aruna V. Vanikar, Rashmi D. Patel, Kamal V. Kanodia and Kamlesh S. Suthar

62

Open access peer-reviewed

3. PET Imaging of Mitochondrial Function in the Living Brain

By Hideo Tsukada

157

Open access peer-reviewed

4. Mitochondrial Proteomic and Molecular Network Alterations in Human Ovarian Cancers

By Xianquan Zhan and Na Li

98

Open access peer-reviewed

5. Mitochondrial Dysfunction as a Key Event during Aging: From Synaptic Failure to Memory Loss

By Claudia Jara, Angie K. Torres, Margrethe A. Olesen and Cheril Tapia-Rojas

236

Open access peer-reviewed

6. Coenzyme Q 10 and L-Carnitine Disturbances in Children with Mitochondrial Diseases

By Ekaterina A. Nikolaeva, Ilgar S. Mamedov and Irina V. Zolkina

139

Edited Volume and chapters are indexed in

  • Worldcat
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  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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