Open access peer-reviewed Edited Volume

Methylation

From DNA, RNA and Histones to Diseases and Treatment

Edited by Anica Dricu

University of Medicine and Pharmacy of Craiova, Romania

Alterations in the normal DNA methylation processes are known to have major consequences for embryonic development and are associated with congenital defects, autoimmunity, aging and malignant transformation. The main purpose of this book is to provide information about the importance of methylation mechanisms in human health and disease. The book, covers the basic mechanism of DNA and protein methylation, aiming at the advanced undergraduate and graduate biomedical students and researchers working in the epigenetic area. The textbook chapters provide background as well as advanced information in the methylation area. On the other hand, it provide readers with both classical and relevant recent discoveries that have been made in the field, pointing out pathways where questions remain.

Read more >Order hardcopy
IntechOpen
MethylationFrom DNA, RNA and Histones to Diseases and TreatmentEdited by Anica Dricu

Published: November 28th 2012

DOI: 10.5772/2932

ISBN: 978-953-51-0881-8

Copyright year: 2012

Books open for chapter submissions

19828 Total Chapter Downloads

9 Crossref Citations

18 Web of Science Citations

34 Dimensions Citations

chaptersDownloads

Open access peer-reviewed

1. Breaking the Silence: The Interplay Between Transcription Factors and DNA Methylation

By Byron Baron

2152

Open access peer-reviewed

2. Diverse Domains of (Cytosine-5)-DNA Methyltransferases: Structural and Functional Characterization

By A. Yu. Ryazanova, L. A. Abrosimova, T. S. Oretskaya and E. A. Kubareva

1964

Open access peer-reviewed

3. Bifunctional Prokaryotic DNA-Methyltransferases

By Dmitry V. Nikitin, Attila Kertesz-Farkas, Alexander S. Solonin and Marina L. Mokrishcheva

1102

Open access peer-reviewed

4. Deciphering Protein Arginine Methylation in Mammals

By Ruben Esse, Paula Leandro, Isabel Rivera, Isabel Tavares de Almeida, Henk J Blom and Rita Castro

1756

Open access peer-reviewed

5. Methylation in Tumorigenesis

By Melissa A. Edwards, Pashayar P. Lookian, Drew R. Neavin and Mark A. Brown

1158

Open access peer-reviewed

6. Circulating Methylated DNA as Biomarkers for Cancer Detection

By Hongchuan Jin, Yanning Ma, Qi Shen and Xian Wang

2656

Open access peer-reviewed

7. DNA Methylation, Stem Cells and Cancer

By Anica Dricu, Stefana Oana Purcaru, Alice Sandra Buteica, Daniela Elise Tache, Oana Daianu, Bogdan Stoleru, Amelia Mihaela Dobrescu, Tiberiu Daianu and Ligia Gabriela Tataranu

1586

Open access peer-reviewed

8. DNA Methylation in the Pathogenesis of Head and Neck Cancer

By Zvonko Magić, Gordana Supić, Mirjana Branković-Magić and Nebojša Jovic

1839

Open access peer-reviewed

9. Host-Mimicking Strategies in DNA Methylation for Improved Bacterial Transformation

By Hirokazu Suzuki

1621

Open access peer-reviewed

10. Messenger RNA Cap Methylation in Vesicular Stomatitis Virus, a Prototype of Non‐Segmented Negative‐Sense RNA Virus

By Jianrong Li and Yu Zhang

2393

Open access peer-reviewed

11. The Methylation of Metals and Metalloids in Aquatic Systems

By Robert P. Mason

1601

Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

Order a hardcopy of the Edited Volume

Free shipping with DHL Express

Hardcover (ex. VAT)£170

Order now

Residents of European Union countries need to add a Book Value-Added Tax of 5%. Institutions and companies, registered as VAT taxable entities in their own EU member state, will not pay VAT by providing IntechOpen with their VAT registration number. This is made possible by the EU reverse charge method.

Special discount for IntechOpen contributors

All IntechOpen contributors are offered special discounts starting at 40% OFF available through your personal dashboard

Login and purchase