Open access peer-reviewed Edited Volume

Germ Line Mutations Associated Leukemia

Edited by Zhan He Wu

University of Sydney

In the current practice of modern medicine, the treatment of infectious and nutritional disorders is well established. In contrast, currently genetic disorders/diseases and cancer constitute a substantial load in the clinic. The care of genetic-based diseases and cancer has become a major task in medical practices worldwide and it is unprecedented. It will be rare for any family to be entirely free of genetic disease, therefore genetic diseases impose a huge burden upon individuals, families, and societies. Modern medicine is at the crossroads in the new genomic era with the development of more and more modern technologies. Remarkable advances have been well achieved in defining and classifying these genetic-associated diseases. The identification of the genetic landscape of germ line mutations-associated leukemia caused by either inherited gene mutations or syndromes has led to a deep understanding of leukemogenesis, recognition of clinical diagnosis, and translation into clinical practice in its specific management strategies.

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Germ Line Mutations Associated LeukemiaEdited by Zhan He Wu

Published: September 4th 2019

DOI: 10.5772/intechopen.77693

ISBN: 978-1-78984-024-7

Print ISBN: 978-1-78984-023-0

eBook (PDF) ISBN: 978-1-78984-403-0

Copyright year: 2019

Books open for chapter submissions

1290 Total Chapter Downloads


Open access peer-reviewed

1. Introductory Chapter: Germline Mutations Associated with Leukaemia - Different Genetic Landscape and Therapeutic Strategies

By Zhan He Wu


Open access peer-reviewed

2. Epigenetic Landscape in Leukemia and Its Impact on Antileukemia Therapeutics

By Bingzhi He, Julia Cathryn Hlavka-Zhang, Richard B. Lock and Duohui Jing


Open access peer-reviewed

3. Familial Leukemia Associated with Thrombocytopenia

By Jakub Trizuljak and Michael Doubek


Open access peer-reviewed

4. Perturbations in Generation and Flow of Energy in the Eukaryotic Cell Explain the Chromosomal Instability Syndrome

By Arturo Solis Herrera


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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