Open access peer-reviewed Edited Volume

Germ Line Mutations Associated Leukemia

Edited by Zhan He Wu

University of Sydney

In the current practice of modern medicine, the treatment of infectious and nutritional disorders is well established. In contrast, currently genetic disorders/diseases and cancer constitute a substantial load in the clinic. The care of genetic-based diseases and cancer has become a major task in medical practices worldwide and it is unprecedented. It will be rare for any family to be entirely free of genetic disease, therefore genetic diseases impose a huge burden upon individuals, families, and societies. Modern medicine is at the crossroads in the new genomic era with the development of more and more modern technologies. Remarkable advances have been well achieved in defining and classifying these genetic-associated diseases. The identification of the genetic landscape of germ line mutations-associated leukemia caused by either inherited gene mutations or syndromes has led to a deep understanding of leukemogenesis, recognition of clinical diagnosis, and translation into clinical practice in its specific management strategies.

Read more >Order hardcopy
IntechOpen
Germ Line Mutations Associated LeukemiaEdited by Zhan He Wu

Published: September 4th 2019

DOI: 10.5772/intechopen.77693

ISBN: 978-1-78984-024-7

Print ISBN: 978-1-78984-023-0

eBook (PDF) ISBN: 978-1-78984-403-0

Copyright year: 2019

Books open for chapter submissions

725 Total Chapter Downloads

chaptersDownloads

Open access peer-reviewed

1. Introductory Chapter: Germline Mutations Associated with Leukaemia - Different Genetic Landscape and Therapeutic Strategies

By Zhan He Wu

100

Open access peer-reviewed

2. Epigenetic Landscape in Leukemia and Its Impact on Antileukemia Therapeutics

By Bingzhi He, Julia Cathryn Hlavka-Zhang, Richard B. Lock and Duohui Jing

196

Open access peer-reviewed

3. Familial Leukemia Associated with Thrombocytopenia

By Jakub Trizuljak and Michael Doubek

267

Open access peer-reviewed

4. Perturbations in Generation and Flow of Energy in the Eukaryotic Cell Explain the Chromosomal Instability Syndrome

By Arturo Solis Herrera

165

Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

Order a hardcopy of the Edited Volume

Free shipping with DHL Express

Hardcover (ex. VAT)£140

Order now

Residents of European Union countries need to add a Book Value-Added Tax of 5%. Institutions and companies, registered as VAT taxable entities in their own EU member state, will not pay VAT by providing IntechOpen with their VAT registration number. This is made possible by the EU reverse charge method.

Special discount for IntechOpen contributors

All IntechOpen contributors are offered special discounts starting at 40% OFF available through your personal dashboard

Login and purchase