Open access peer-reviewed Edited Volume

Future Aspects of Tumor Suppressor Gene

Edited by Yue Cheng

University of Hong Kong, China

Tumor suppressor genes (TSGs) and their signaling networks are fast growing areas in current biomedical science. These groups of genes, which are not limited to tumor suppression, play critical roles in many cellular activities. This book, "Future Aspects of Tumor Suppressor Genes", contains some fascinating fields, from basic to translational researches, in recent TSG studies. For example, several TSG signaling pathways are addressed in this book, and both mouse and Drosophila models used for the exploration of these genes are described based on the experimental evidence. A detailed review for current knowledge of microRNA studies in the regulation of tumor growth is introduced. Additionally, how natural compounds interfere with the progression of cancer development via TSG pathways is systemically summarized. Recent progresses in cell reprogramming and stemness transition processes regulated by TSG pathways are also included in this book.

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Future Aspects of Tumor Suppressor GeneEdited by Yue Cheng

Published: April 10th 2013

DOI: 10.5772/56471

ISBN: 978-953-51-1063-7

eBook (PDF) ISBN: 978-953-51-7124-9

Copyright year: 2013

Books open for chapter submissions

14391 Total Chapter Downloads

6 Crossref Citations

12 Web of Science Citations

17 Dimensions Citations


Open access peer-reviewed

1. Strain-Specific Allele Loss: An Important Clue to Tumor Suppressors Involved in Tumor Susceptibility

By Nobuko Mori and Yoshiki Okada


Open access peer-reviewed

2. To Grow, Stop or Die? – Novel Tumor-Suppressive Mechanism Regulated by the Transcription Factor E2F

By Eiko Ozono, Shoji Yamaoka and Kiyoshi Ohtani


Open access peer-reviewed

3. MicroRNAs and lncRNAs as Tumour Suppressors

By Emanuela Boštjančič and Damjan Glavac


Open access peer-reviewed

4. Roles of Tumor Suppressor Signaling on Reprogramming and Stemness Transition in Somatic Cells

By Arthur Kwok Leung Cheung, Yee Peng Phoon, Hong Lok Lung, Josephine Mun Yee Ko, Yue Cheng and Maria Li Lung


Open access peer-reviewed

5. Modeling Tumorigenesis in Drosophila: Current Advances and Future Perspectives

By Fani Papagiannouli and Bernard M. Mechler


Open access peer-reviewed

6. Polyphenolic Compounds Targeting p53-Family Tumor Suppressors: Current Progress and Challenges

By Nelly Etienne-Selloum, Israa Dandache, Tanveer Sharif, Cyril Auger and Valérie B. Schini-Kerth


Open access peer-reviewed

7. START-GAP/DLC Family Proteins: Molecular Mechanisms for Anti-Tumor Activities

By Hitoshi Yagisawa


Open access peer-reviewed

8. MIG-6 and SPRY2 in the Regulation of Receptor Tyrosine Kinase Signaling: Balancing Act via Negative Feedback Loops

By Yu-Wen Zhang and George F. Vande Woude


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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