Open access peer-reviewed Edited Volume

The Hippocampus

Plasticity and Functions

The hippocampus is an important brain region, a true central hub for memory of various kinds and other processes. Neuropsychiatric disorders such as Alzheimer's disease, drug addiction, and schizophrenia are characterized by hippocampal alterations. The dentate gyrus of the hippocampus is a site exhibiting adult neurogenesis. This book covers the topic of the hippocampus from various perspectives. It discusses adult neurogenesis, effect of enriched environments on hippocampal plasticity, and long-term potentiation-associated gene expression. The book also addresses multiscale representations of complex environments and strategies in the hippocampus-dependent spatial tasks. Finally, insight into the hippocampus as a link between negative affect and relapse to psychostimulants is provided. The book collects evidence of various hippocampal functions in healthy and disordered brain.

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The HippocampusPlasticity and FunctionsEdited by Ales Stuchlik

Published: July 11th 2018

DOI: 10.5772/intechopen.68877

ISBN: 978-1-78923-357-5

Print ISBN: 978-1-78923-356-8

eBook (PDF) ISBN: 978-1-83881-359-8

Copyright year: 2018

Books open for chapter submissions

6819 Total Chapter Downloads

12 Crossref Citations

5 Web of Science Citations

28 Dimensions Citations


Open access peer-reviewed

1. How Does an Enriched Environment Impact Hippocampus Brain Plasticity?

By Hadi Zarif, Sarah Nicolas, Agnès Petit-Paitel, Joëlle Chabry and Alice Guyon


Open access peer-reviewed

2. Factors Regulating Neurogenesis in the Adult Dentate Gyrus

By Lei Zhang and Xinhua Zhang


Open access peer-reviewed

3. Long-Term Potentiation-Associated Gene Expression: Involvement of the Tumour Protein p53

By Pavel D. Lisachev and Mark B. Shtark


Open access peer-reviewed

4. A Role for the Longitudinal Axis of the Hippocampus in Multiscale Representations of Large and Complex Spatial Environments and Mnemonic Hierarchies

By Bruce Harland, Marcos Contreras and Jean-Marc Fellous


Open access peer-reviewed

5. The Importance of Distinguishing Allocentric and Egocentric Search Strategies in Rodent Hippocampal-Dependent Spatial Memory Paradigms: Getting More Out of Your Data

By Adrienne M. Grech, Jay Patrick Nakamura and Rachel Anne Hill


Open access peer-reviewed

6. The Hippocampus as a Neural Link between Negative Affect and Vulnerability for Psychostimulant Relapse

By Jeffrey L. Barr, Brenna Bray and Gina L. Forster


Edited Volume and chapters are indexed in

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  • CNKI

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