Open access peer-reviewed Edited Volume


Tools in Oncology

The first chapters of the volume "Cytokeratins - Tools in Oncology" discuss multiple functions of cytokeratins in organization of the intermediary filaments in normal intestine and liver as well as microfold L cells and the usability of cytokeratins 7, 8 and 20 in tumor diagnosis in detail. Epithelial to mesenchymal transition as a mechanism important in pathogenesis is touched in another chapter, followed by several articles dealing with the role of cytokeratins for detection of disseminated tumor cells and as response markers during chemotherapy. This book is therefore destined to all cancer researchers and therapists who want to understand the diagnostic application of cytokeratins in histology and, especially, the use of anti-cytokeratin antibodies to identify viable residual tumor cells accounting for a higher risk of tumor recurrence or cancer cells responding to chemotherapy, respectively.

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CytokeratinsTools in OncologyEdited by Gerhard Hamilton

Published: February 29th 2012

DOI: 10.5772/1888

ISBN: 978-953-51-0047-8

eBook (PDF) ISBN: 978-953-51-6818-8

Copyright year: 2012

Books open for chapter submissions

20283 Total Chapter Downloads

8 Crossref Citations

15 Web of Science Citations

18 Dimensions Citations


Open access peer-reviewed

1. The Expression of Cytokeratins in Bovine Intestinal Microfold (M) Cells

By Takashi Kanaya, Tetsuya Hondo,Kohtaro Miyazawa, Michael T. Rose and Hisashi Aso


Open access peer-reviewed

2. Cytokeratins of the Liver and Intestine Epithelial Cells During Development and Disease

By Priti Chougule and Suchitra Sumitran-Holgersson


Open access peer-reviewed

3. Epithelial to Mesenchymal Transition in Microbial Pathogenesis

By Abderrahman Chargui,Mimouna Sanda,Patrick Brest, Paul Hofman and Vouret-Craviari Valérie


Open access peer-reviewed

4. Cytokeratin 7 and 20

By Agnieszka Jasik


Open access peer-reviewed

5. Cytokeratin 8: The Dominant Type II Intermediate Filament Protein in Lung Cancer

By Nobuhiro Kanaji, Akihito Kubo, Shuji Bandoh, Tomoya Ishii,Jiro Fujita, Takuya Matsunaga and Etsuro Yamaguchi


Open access peer-reviewed

6. Cytokeratin 18 (CK18) and CK18 Fragments for Detection of Minimal Residual Disease in Colon Cancer Patients

By Ulrike Olszewski-Hamilton, Veronika Buxhofer-Ausch,Christoph Ausch and Gerhard Hamilton


Open access peer-reviewed

7. FISH Probe Counting in Circulating Tumor Cells

By Sjoerd T. Ligthart, Joost F. Swennenhuis,Jan Greve and Leon W.M.M. Terstappen


Open access peer-reviewed

8. Cytokeratin 18 (CK18) and Caspase-Cleaved CK18 (ccCK18) as Response Markers in Anticancer Therapy

By Hamilton Gerhard


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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