Open access peer-reviewed Edited Volume


Pavol Svorc

Pavol Josef Safarik University


Synchronization Desynchronization Endogenous Rhythm Exogenous Rhythm Cardiovascular Arrhythmia Heart rate Variability Sympathetic Activity Parasympathetic Activity Endocrine System Diseases Renal System Diseases Digestive System Diseases

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About the book

Chronobiology is the science investigating and objectively quantifying the mechanisms of the biological time structure, including the rhythmic manifestations of life. The disturbance of the temporal structure of the living organism leads to disturbed harmony between biological rhythms the rhythm of external environment which often results in manifestations of various diseases. Circadian disruption may occur, and may be the result of phase shifts in the oscillation of the circadian and activity-controlled physiological processes, or can be induced by factors related to periodic inputs. For example, low contrast between day and night synchronizing signals; by Zeitgebers with different periods or unusual phasing or by Zeitgeber shifts (jet lag syndrome, shift work); factors related to oscillators (the uncoupling between the different oscillators inside the SCN, the uncoupling between the central and peripheral oscillators or clock gene functional alterations). Chronobiological disturbance can also be induced by factors related to outputs such as nocturnal melatonin suppression or loss of cortisol rhythm. Many pathological states can be promoted or impaired as consequences of circadian disruption. This planned book publication will include articles on recent research in the field of human chronobiology as well as experimental and clinical medicine.

Publishing process

Book initiated and editor appointed

Date completed: January 9th 2019

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline Extended: Open for Submissions

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

Approved chapters written in full and submitted

Deadline for full chapters: March 31st 2019

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: June 19th 2019

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: August 18th 2019

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About the editor

Pavol Svorc

Pavol Josef Safarik University

Dr. Pavol Švorc is an Associate Professor, Doctor of the Natural Sciences, Philosophe Doctor. In 1982 he became a Doctor of the Natural Sciences from General Biology, Natural Faculty, Šafarik’s University in Košice. In 1995 he received a PhD. – Physiology and Patophysiology, Natural Faculty Šafarik’s University in Košice. In 2005 he became an Associate Professor from Normal and Patological Physiology, Medical Faculty, Šafarik’s University in Košice. From 1982 to 1983 Dr.Švorc worked as an independent specialist in the local museum in Poprad, Slovakia. In 1983 he started working as a lecturer at the Department of Physiology, Šafarik’s University in Kosice, Slovakia. From 2011 until 2014 he was a Head of the Institute of Physiology and Pathophysiology, Medical Faculty, University of Ostrava, Czech Republic. His research interest includes: Chronobiology of cardiovascular system, respiratory system and autonomic nervous system.

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Book chapters authored 4

Books edited 1

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