About the book
Rabies, a zoonotic viral disease, which is fatal once clinical manifestations develop, has been known to mankind since ancient times. It's agent, rabies virus (RABV), is (-)ssRNA virus belonging to the order Mononegavirales, the family Rhabdoviridae (from the Latin word “rhabdos”, meaning “rod”, because representatives of this family have rod-shaped virions), and the genus Lyssavirus (from the name “Lyssa”, an ancient Greek goddess, the personification of rabies).
Despite significant progress in fighting rabies worldwide and successful eradication programs in Western Europe, rabies remains an important public health concern, causing approximately 50,000 human cases per year. It was demonstrated that rabies is present on every continent except Antarctica, with 95% of human deaths occurring in Asia and Africa. In almost 99% of cases, transmission of RABV to humans occurs from domestic dogs. However, rabies can affect both domestic and wild animals and can be transmitted to humans through bites or scratches, usually through saliva.
This book aims to summarize current knowledge regarding RABV, its prevalence and genetic diversity, modern approaches to its diagnosis, prevention and treatment. It is our hope that the book presented will be useful to scientists, doctors, postgraduate students, and students studying the problem of rabies, conducting research, carrying out preventive measures and providing medical care to patients.