Open access peer-reviewed Edited Volume

Renal Cell Carcinoma - Recent Advances, New Perspectives and Applications

Jindong Chen

University of Rochester Medical Center

A pioneering researcher in renal cell carcinoma, AACR active member, winner of AACR-Bristol Myers and AACR-Sanofi Aventis Awards, who cloned four RCC-related genes, and developed five kidney cancer knockout, mouse models.


Genetics of Kidney Cancer Risk Factors Environment Diagnosis of Renal Cell Carcinoma Imaging Techniques Renal Tumor Biopsy Pathology of Renal Cell Carcinoma Management of Renal Cell Carcinoma Therapy of Renal Cell Carcinoma Surgery of Kidney Cancer Prognostic Factors in Renal Cell Carcinoma Prognostic Models in Kidney Cancer

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About the book

Kidney cancer is one of the top human malignancies in the world. This book will address the different aspects of kidney cancer including genetics, epidemiology, therapy, and management of renal cell carcinoma. It aims to offer all physicians treating renal cell carcinoma, as well as researchers, updated information concerning the biology, diagnosis, screening, imaging, surgery (regular surgery, robotic surgery, and surgical strategies), therapy (target therapy, adjuvant therapy, immunotherapy, focal therapy, and other new systemic approaches). This book will provide a detailed evaluation of diagnostic modalities, an in-depth analysis of screening for renal cell carcinoma, recent advances in treatment, principles, and trends in the management of renal cell carcinoma. This updated knowledge will be an interesting and informative read for any clinician involved in the management of patients with renal cell carcinoma. In addition, readers such as related physicians, researchers, and patients with renal cell carcinomas are potential beneficiaries of this book.

Publishing process

Book initiated and editor appointed

Date completed: April 22nd 2022

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline Extended: Open for Submissions

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

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Approved chapters written in full and submitted

Deadline for full chapters: July 19th 2022

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: October 7th 2022

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: December 6th 2022

All chapters are copy-checked and typesetted before being published. IntechOpen regularly submits its books to major databases for evaluation and coverage, including the Clarivate Analytics Book Citation Index in the Web of ScienceTM Core Collection. Other discipline-specific databases are also targeted, such as Web of Science's BIOSIS Previews.

About the editor

Jindong Chen

University of Rochester Medical Center

Jindong Chen, Ph.D., AACR active member, Research Associate Professor, Laboratory Co-director, Department of Urology, University of Rochester Medical Center, New York, USA. He obtained his Ph.D. in Karolinska Institute, Sweden. Then, he served as Research Scientist at Van Andel Research Institute, USA; Senior Scientist at National Cancer Centre Singapore and NUS-Duke University Graduate School. He has worked on colorectal carcinoma, breast cancer, and kidney cancer for more than 20 years. He identified two cancer-related genes, NORE1 and LSAMP by positional cloning strategy, and was awarded in the 94th AACR annual meeting. Afterward, he has successfully developed several FLCN and HRPT2 conditional knockout mouse models and was again awarded in the 100th AACR annual Meeting for generating a tumor-developing FLCN knockout mouse model. By using those mouse models, he has conducted quite a few anti-cancer drug tests.

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