Patrick Arbuthnot is Personal Professor and Director of the Antiviral Gene Therapy Research Unit of the University of the Witwatersrand (Wits) in South Africa. After graduating with a medical degree from Wits, Patrick Arbuthnot completed a PhD in 1992. From 1993 to 1994, he worked as a post-doctoral researcher at Necker Hospital in Paris, and investigated the development of gene therapy for treating liver cancer and hepatitis B virus (HBV) infection. On returning to South Africa, Patrick Arbuthnot established the Antiviral Gene Therapy Research Unit. This unit is now a Centre of Excellence of the African Network for Drug and Diagnostic Innovation (ANDI). The unit has a research interest in HBV infection, liver cancer, HIV-1 infection and developing new methods of treating these diseases.