Hiroshi Sakagami

Meikai University Japan

Hiroshi Sakagami received his Ph.D. from Faculty of Pharmaceutical Sciences, University of Tokyo. He worked for 17 years in the Department of Biochemistry, School of Medicine, Showa University, with a 3 year post-doctoral stay at Roswell Park Memorial Institute, Buffalo, NY. Since 1997 he has been working as a professor at the Division of Pharmacology, Meikai University School of Dentistry, and also as the director of Media Center and chairman of international exchange program. His research interest includes the structure and the biological function of lignin-carbohydrate complex (LCC), the application of LCC-containing plant extract to oral diseases, and the quest for the compounds that specifically kill oral squamous cell carcinoma.

Hiroshi Sakagami

2books edited

5chapters authored

Latest work with IntechOpen by Hiroshi Sakagami

Licorice extracts are used as additive to many Kampo medicines to alleviate pain and inflammation. With rapid progress of analytical methodology, its action mechanism is being elucidated. This book is composed of three sections. Section 1 introduces licorice as alternative medicine, its application in the industry, and the trading/market prospects between Japan and China. Section 2 summarizes the purification/identification steps of licorice ingredients and their antioxidant, antimicrobial, PPAR-? ligand-binding, antitumor, antiviral, and in vitro fertilization activities. Section 3 proposes the possible molecular mechanism by which licorice ingredients induce anti-inflammatory, antifibrosis, antihepatitis, and antileishmanial activity. All chapters are written by experts of natural sciences and economics and will surely give new insights into alternative medicines to students, clinicians, teachers, and researchers.

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