James W. Paxton completed his PhD in steroid biochemistry and porphyria at the University of Glasgow in 1973. He then continued on to a postdoctoral position in the Department of Materia Medica at the same university. In 1976, he was awarded a Merck, Sharpe, and Dohme Fellowship in the Department of Medicine at the University of Auckland, New Zealand. This was followed by a Senior MRC Research Fellowship in the Department of Pharmacology and Clinical Pharmacology and, in 1985, he was appointed as Senior Lecturer in Pharmacology. In 1997, he received the University of Auckland Distinguished Teaching Award and, in 1999, was appointed as Head of the Department. His research interests have primarily focused on ADME and pharmacokinetics, in particular, of novel anticancer agents. Other research interests include placental pharmacology, targeted drug delivery, reversal of MDR, and phytochemical transport. He has written over 160 research papers and reviews published in these areas.