Daniela Cihakova

Johns Hopkins UniversityUnited States of America

Dr. Daniela Cihakova is an Assistant Professor and Director of Immunologic Disorders Laboratory at Department of Pathology, Johns Hopkins University in Baltimore, Maryland, United States. Dr. Cihakova was born in the Czech Republic and received her MD and PhD from Charles University, Prague, Czech Republic. Her research focuses on the pathogenesis of autoimmune diseases. In particular, she has concentrated on studying myocarditis and dilated cardiomyopathy using a mouse model of myocarditis called experimental autoimmune myocarditis. With her colleagues, she has recently discovered that Il13 is protective in myocarditis and that IL17A drives the development of dilated cardiomyopathy. She also works on examining the role of monocyte and macrophages during myocarditis pathogenesis. Her other research interests include Sjogren’s syndrome, congenital complete heart block, autoimmune polyglandular syndrome type 1 (APECED) and vasculitis.

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Latest work with IntechOpen by Daniela Cihakova

Myocarditis, the inflammation of the heart muscle, could be in some cases serious and potentially fatal disease. This book is a comprehensive compilation of studies from leading international experts on various aspects of myocarditis. The first section of the book provides a clinical perspective on the disease. It contains comprehensive reviews of the causes of myocarditis, its classification, diagnosis, and treatment. It also includes reviews of Perimyocarditis; Chagas' chronic myocarditis, and myocarditis in HIV-positive patients. The second section of the book focuses on the pathogenesis of myocarditis, discussing pathways and mechanisms activated during viral infection and host immune response during myocarditis. The third, and final, section discusses new findings in the pathogenesis that may lead to new directions for clinical diagnosis, including use of new biomarkers, and new treatments of myocarditis.

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