Linda Eva Amoah

University of Ghana

Linda Eva Amoah, Associate Professor of Immunology at the University of Ghana’s Noguchi Memorial Institute, specializes in malaria elimination, malaria diagnostics, asymptomatic infections, gametocyte biology, and transmission-blocking immunity. She is the Principal Investigator for several grants, including some awarded by the Bill and Melinda Gates Foundation, National Institutes of Health (NIH), and the Research Institute for Development (IRD). She serves on the editorial board for Frontiers and other journals and has published more than seventy scientific articles.

1books edited

1chapters authored

Latest work with IntechOpen by Linda Eva Amoah

The many control efforts against malaria have led to averting many but not all malaria-related deaths; thus, malaria remains a major public health challenge, especially in Sub-Saharan Africa. This suggests that factors permissive of malaria parasite perpetuation are still in operation. An understanding of the dynamics of these factors and sufficient deployment of antimalarial strategies are crucial for the control and elimination of the disease. This book identifies environmental factors supporting vector survival, behavior, and access to human hosts, as well as the phenomenon of asymptomatic malaria infections, as some of the important factors of malaria transmission. It also discusses contemporary developments of malaria diagnostic tools with improved sensitivity, patient friendliness, and minimal requirements for sophisticated equipment or skills. Finally, this book also provides an overview of current insights into the malaria treatment landscape, which depends on the parasite species, disease severity, and drug susceptibility profiles of local parasites, among others.

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Malaria

Edited by Linda Eva Amoah

Chapters authored

Progress in Parasite Genomics and Its Application to Current Challenges in Malaria Control

By Cheikh Cambel Dieng, Colby T. Ford, Jennifer Huynh, Linda E. Amoah, Yaw A. Afrane, Daniel A. Janies and Eugenia Lo

A wide deployment of malaria control tools have significantly reduced malaria morbidity and mortality across Africa. However, in the last five to seven years, there has been a resurgence of malaria in several African countries, raising the questions of whether and why current control mechanisms are failing. Since the first Plasmodium falciparum reference genome was published in 2002, few thousands more representing a broad range of geographical isolates have been sequenced. These advances in parasite genomics have improved our understanding of mutational changes, molecular structure, and genetic mechanisms associated with diagnostic testing, antimalarial resistance, and preventive measures such as vaccine development. In this chapter, we summarize the current progress on: (1) genomic characteristics of P. falciparum; (2) novel biomarkers and revolutionary techniques for diagnosing malaria infections; and (3) current vaccine targets and challenges for developing efficacious and long-lasting malaria vaccines.

Part of the book: Current Topics and Emerging Issues in Malaria Elimination

Linda Eva Amoah

Latest work with IntechOpen by Linda Eva Amoah

Malaria

Chapters authored

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