Chapters authored
Application of Urine Metabolomics as a Marker in Health and Disease
Advances in metabolomics research have yielded an avenue for utilizing this laboratory-based modality as a platform for clinical diagnosis, identification of novel biomarkers, and longitudinally monitoring the health status of individuals from normal physiological and pathophysiological perspectives. This chapter provides insight on the application of urinalysis in health and disease from the standpoint of deciphering a larger span of metabolite and biomarker identification using metabolomics, specifically focusing on infectious diseases, oncology, metabolic, and inflammatory diseases in humans.
Part of the book: Advances and Challenges in Urine Laboratory Analysis
Efficacy of Selenium for Controlling Infectious Diseases
Selenium, an essential micronutrient for both animals and humans, has been documented to possess antimicrobial properties against a wide range of pathogenic microorganisms. One of the primary mechanisms by which selenium exerts its antimicrobial activity is through the generation of reactive oxygen species that can damage microbial cells. Besides its direct antimicrobial effects, selenium can enhance the immune response to infections, making it a potential tool in the prevention and treatment of infectious diseases. Given the growing threat of antibiotic resistance and the need for alternative therapeutic options, the antibacterial properties of selenium are of interest to the scientific community. This book chapter will summarize the current state of knowledge on the antibacterial properties of selenium, and its potential clinical applications as a therapeutic agent against infectious diseases. Further, the chapter explores the limitations and challenges associated with the use of selenium as an antibacterial agent.
Part of the book: Selenium and Human Health