Feyzi Birol Sarica

Giresun University

Feyzi Birol Sarica graduated in medicine from Ankara University in 1997. Following the presentation of his thesis, “Prognostic factors in Supratentorial Glial Tumors”, at the Ankara Numune Education and Research Hospital, he was certified as a neurosurgeon. Between 2006 and 2015 he worked first as a neurosurgeon and then as a lecturer at Adana Education and Research Hospital, Baskent University. Further appointments were at Kudret International Hospital in Ankara, and the Department of Neurosurgery at Giresun University, where he became an associate professor in 2018. He is a member of the Turkish Neurosurgical Society and the Nervous System Surgery Association.

1books edited

4chapters authored

Latest work with IntechOpen by Feyzi Birol Sarica

Central nervous system (CNS) tumors are a heterogeneous group consisting of more than 100 tumor types originating from the brain, cerebellum, brain stem, spinal cord, and meninges. Despite the positive developments of recent years, especially in the treatment of high-grade brain tumors, treatment outcomes have not yet reached an acceptable level. However, due to advances in clinical and experimental studies, the genetic and molecular structures of many high-grade CNS tumors are now better understood. The World Health Organization’s 2021 Classification of CNS Tumors has aided the understanding of the genetic, molecular and immunological structures of these tumors as well as their interactions with their microenvironment. Targeted therapies and vaccines developed with immunotherapy protocols are promising developments. This book explores the natural history of CNS tumors and discusses relevant treatment protocols.

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Central Nervous System Tumors

Edited by Feyzi Birol Sarica

Chapters authored

Herpes Simplex Type 1 Encephalitis

By Feyzi Birol Sarica

Part of the book: Non-Flavivirus Encephalitis

Surgical Principles for Spinal and Paraspinal Neurofibromas

By Feyzi Birol Sarica

Neurofibromas are the most prevalent seen tumor in the neurofibromatosis type 1 (NF1) disease. Spinal neurofibromas, which are the major diagnostic criteria of disease, are seen in approximately 60% of the patients with NF1. They constitute 23% of all of the spinal tumors. While the spinal neurofibromas most frequently show a location in thoracic region, it is followed by their predilection in cervical and lumbar regions, respectively. The spinal neurofibromas located in the sacral region are quite rarely observed and show an asymptomatic course until reaching to the big sizes. Of these spinal neurofibromas, 72% were with intradural extramedullary, 14% with extradural, and 13% with intradural and extradural “dumbbell formation.” Only 1% of the spinal neurofibromas are intramedullary located. The total taking of the single solitary neurofibroma surgically is relatively easier. But, the difficulties can be encountered in taking these tumors surgically since they are characterized by the multiple tumors in the plexiform neurofibromas, especially accompanying to the NF1. In this chapter, the surgical difficulties encountered in the region in which the tumor is localized and different surgical approaches are developed in the course of time in order to exceed these difficulties are described.

Part of the book: Brain and Spinal Tumors

Introductory Chapter: Significant Updates for Brain Tumors to the 2021 WHO Classification of the CNS Tumors (WHO CNS5) and Clinical Overview – Molecular Translation of the Brain Tumors

By Feyzi Birol Sarica

Part of the book: Central Nervous System Tumors

Surgical Principles for Spinal Meningiomas

By Feyzi Birol Sarica

Spinal meningiomas, which are usually benign character, rarely show an invasive course. Since they grow slowly in the intradural extramedullary space, clinical symptoms also progress slowly. It is usually diagnosed in the later periods, when the tumor reaches to large size. They most commonly show location in the thoracic region. Although it does not have a real capsule, they can be removed completely or close to total by microsurgical methods, since they are well-demarcated solitary tumors. The most important factor in the complete and safe removal of spinal meningioma is the selection of the surgical approach suitable for the size, localization, and topography of the tumor. In the postoperative period, improvement in neurological functions is observed generally and their prognosis is good. In this study, the natural history of the tumor is explained in detail, by examining the pathogenesis and predisposing factors and clinical symptomatology in the spinal meningiomas. Moreover, it has been also focused on describing the surgical approaches and operative techniques to be used in the complete and safe removal of the spinal meningioma, according to the localization and topography of the tumor.

Part of the book: Central Nervous System Tumors

Feyzi Birol Sarica

Latest work with IntechOpen by Feyzi Birol Sarica

Central Nervous System Tumors

Chapters authored

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