Questionnaire on THM prescriptions of TKM doctors.
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Nieto Nieto and Alejandro Sanchez Garcia",authors:[null]},{id:"12082",title:"Structure and Property of the Singularity Loci of Gough-Stewart Manipulator",slug:"structure-and-property-of-the-singularity-loci-of-gough-stewart-manipulator",signatures:"Yi Cao, Yanwen Li and Zhen Huang",authors:[null]}]}]},onlineFirst:{chapter:{type:"chapter",id:"68812",title:"The Utilization of Traditional Herbal Medicine for Treatment in Traditional Korean Medicine Clinics",doi:"10.5772/intechopen.88714",slug:"the-utilization-of-traditional-herbal-medicine-for-treatment-in-traditional-korean-medicine-clinics",body:'\nTraditional herbal medicines (THMs) are the most popular and preferred forms of traditional medicines (TMs) [1, 2, 3]. The World Health Organization (WHO) estimated that 80% of the population in developing countries rely on traditional herbs for their primary health care [4]. Compared with the developed countries, in the United States of America (USA), 19% of the population uses THMs for their treatment [5].
\nTHMs have gained an increasing popularity in the last two decades in the industrialized countries [6, 7, 8]. The Europe market for THMs is estimated to be valued at $5.18 billion in 2016 [9]. The American botanical council reported that the sales of THMs in the USA reached a total of $7.45 billion in 2016 [10]. Thus, the global THM market is expected to grow and reach $129.68 billion by 2023 [11].
\nTMs, such as traditional Chinese medicines (TCMs), Ayurveda, Kampo, traditional Korean medicines (TKMs), and Unani, have used herbal medicines for hundreds or even thousands of years worldwide [6, 12, 13, 14, 15]. Before Western medicine was introduced, TMs, especially herbal medicines, were used for preventing and treating diseases in many nations [16]. The use of THMs is well established, and it is widely known to be safe and effective [17].
\nTM practitioners in Asian countries, such as China, South Korea, and Taiwan, practice TM treatment in medical clinics as doctors defined by law [18, 19]. South Korea has the highest percentage (15.26%) of TM doctors in medical clinics in East Asia, followed by China (12.63%) and the Taiwan region (9.69%) [18].
\nKoreans have traditionally used herbs for treatment and prevention of diseases. In 1894, Je Ma Lee, a TKM doctor, established the theory of Sasang constitutional medicine (SCM), which is a unique TKM form [14, 20]. Based on the SCM theory, humans are categorized into four constitution types: Taeyangyin (Greater Yang type), Tae-eumin (Greater Yin type), Soyangyin (Lesser Yang type), and Soeumin (Lesser Yin type) [14, 20]. SCM has classified therapeutic THMs according to the four constitutions because THMs that respond to the characteristics of four constitutions are different [14, 20].
\nIn South Korea, TKM is legally institutionalized and covered by national insurance [18]. Since 1987 herbal extracts based on good manufacturing practice (GMP) are covered by health insurance, but the decoction type of traditional herbal medicines (THMs) which is combined with two or more medicinal herbs is still not insured yet [18]. In addition, as a member of the WHO Pharmacovigilance, Korea is monitoring adverse drug reactions, including THMs [21].
\nThe Korean Ministry of Food and Drug Safety (MFDS) introduced the Good Manufacturing Practice for herbs (hGMP) in 2012 and made it mandatory in 2015 [22]. Thus, medicinal herbs must be manufactured by the hGMP facilities that are licensed by the Korean MFDS [22].
\nStandards for commonly used herbal materials and preparations are included in the “Korean Pharmacopoeia (KP)” and “Korean Herbal Pharmacopoeia (KHP)” [23]. As of 2019, there are 601 kinds of herbal materials called medicinal herbs listed in the “Korean Pharmacopeia” and “Korean Herbal Pharmacopoeia” [24, 25]. The amount of hazardous substances (e.g., heavy metals, pesticides, aflatoxins, sulfur dioxide, and benzopyrene) in herbal materials is restricted by the “Regulations on Limits and Test Methods for Residues and Contaminants in Herbal Medicines” [26].
\nAccording to the Korea medical law, TKM clinics should utilize medicinal herbs certified by the Korean MFDS [22]. Since 2015, TKM clinics have been using THMs composed of medicinal herbs for treating diseases and promoting health.
\nTHMs are the second most commonly used treatment in South Korea, mainly utilized as a combination of two or more medicinal herbs [27, 28]. In addition, they are used in various forms, such as a decoction, powder, tablet, soft extract, paste, and pill [27].
\nIn previous studies related to Korean THMs, Fan [23] reviewed the role of MFDS in THM management: pre-market approval, post-market inspection, and management of the product quality system. Choi [29] reported that THMs are standardized, regulated, and quality controlled by MFDS guidelines such as KP and KHP. Park [18] investigated the TKM system and summarized development of TM system, policy, education system, medical insurance coverage, and herbal drug monitoring system. Yarnell [30] introduced herbal medicine market and modernized decoction device of TKM hospitals.
\nTo the best of our knowledge, this is the first study aims to shed some light on the overall status of THM usage in South Korea (TKM clinics). The objective of this research was to examine the medical use of THMs, particularly mixtures of THMs, in South Korea, a country with an extensive knowledge and experience in THM use for preventing and treating diseases.
\nThe cross-sectional study design has been used to address the research goals.
\nThe population of the study included TKM doctors who worked at the TKM clinics. Inclusion and exclusion criteria are as follows:
\nAll TKM doctors who used to prescribe THMs and provide their consent form have been included.
\nThe survey group of THM consumption included individuals who worked at TKM clinics, hospitals (TKM, long-term care, and general hospitals), traditional herbal medicine pharmacies, and community pharmacies. In the study, 1354 TKM doctors working in TKM clinics were included. Among them, 1346 respondents were selected for the final analysis, excluding 8 who said they do not prescribe THMs.
\nThe questionnaire adopted and used in this study has been developed by the Korea Ministry of Health and Welfare (MHW), and the National Statistics of Korea reviewed and approved the questionnaire [27]. The 10-page structured questionnaire contained questions on the use, experience, treatment, management status, preference form, number of prescriptions, prescription purpose, frequently prescribed THMs for treatment, ways to purchase herbs, reasons for difficulty in purchase herbs, and plans to expand the use of THMs [27].
\nThere are four sections used in the analysis: the number of THM prescriptions per year, prescription purpose when prescribing THMs, diseases treated with THMs, and THMs used for the disease [27]. The used questionnaire is shown in Table 1.
\n1. How many prescription cases are being used in the practice? (1) Decoction types of THMs: ______________ cases (2) Non-decoction types of THMs: ______________ cases | \n
2. What is the prescription purpose rate when prescribing herbal medicines? (total 100%) (1) Diseases treatment _________% (2) Health improvement _________% (3) Beauty _________% (4) Traffic accident _________% (5) Others _________% | \n
3. Which disease prescribed herbal medicine the most when treating the disease? (1) Which disease prescribed decoction types of THMs the most when treating the disease? ① Musculoskeletal disease ② Neurological disease ③ Cerebrovascular disease ④ Cardiovascular disease ⑤ Cancer ⑥ Endocrine disease ⑦ Digestive disease ⑧ Respiratory disease ⑨ Mental disease ⑩ Obstetrics and gynecology disease ⑪ Urogenital disease ⑫ Skin disease ⑬ Disease in eyes and ears ⑭ Others (2) Which disease prescribed non-decoction types of THMs the most when treating the disease? ① Musculoskeletal disease ② Neurological disease ③ Cerebrovascular disease ④ Cardiovascular disease ⑤ Cancer ⑥ Endocrine disease ⑦ Digestive disease ⑧ Respiratory disease ⑨ Mental disease ⑩ Obstetrics and gynecology disease ⑪ Urogenital disease ⑫ Skin disease ⑬ Disease in eyes and ears ⑭ Others | \n
4. Which disease prescribed herbal medicine the most when treating the disease? \n
| \n
Questionnaire on THM prescriptions of TKM doctors.
TKM: Traditional Korean medicine
THM: Traditional herbal medicine
Descriptive statistics (mean and proportions) were used to describe the characteristics of the representatives of TKM clinics in the sample. Cross-analysis was used to determine the relationships between the high frequency of disease and prescription. All data analyses were performed using SPSS software (version 21.0 for Windows; IBM cop., Armonk, United States).
\nA total number of 1346 TKM doctors participated in this study, 1204 were men (89.5%) and 142 were women (10.5%). Most of them (73.5%) aged between 41 and 60. Out of the 1346 clinics, 779 (57.9%) were located in the capital area, while the rest 567 (42.1%) were located in the noncapital area. Majority of the participants 882 (65.5%) were with less than 20 years of clinical experience, 417 (31.0%) were with 21–38 years of treatment experience, and 47 (3.5%) of them were with 39–56 years of experience, as shown in Table 2.
\nFactors | \nN (%) | \n
---|---|
Gender | \n|
Male | \n1204 (89.5) | \n
Female | \n142 (10.5) | \n
Age (years) | \n|
30–40 | \n191 (14.2) | \n
41–50 | \n550 (40.8) | \n
51–60 | \n440 (32.7) | \n
≥61 | \n165 (12.3) | \n
Place of work | \n|
Capital area | \n779 (57.9) | \n
Chungcheong Province | \n122 (9.1) | \n
Gyeongsang Province | \n287 (21.3) | \n
Jeolla Province | \n158 (11.7) | \n
Clinical experience | \n|
≤20 | \n882 (65.5) | \n
21–38 | \n417 (31.0) | \n
39–56 | \n47 (3.5) | \n
Demographics of participating TKM doctors.
TKM: Traditional Korean medicine
Results showed that 1346 of the TKM doctors prescribed an average of 590.4 ± 1105.5 decoction types of THMs/year, and the prescription distribution was as follows: 378 (28.1%) had ≤200 cases, 428 (31.8%) had 201–400 cases, 256 (19.0%) had 401–600 cases, and 284 (21.1%) had ≥601 cases (Table 3).
\nPrescription frequency | \nN (%) | \nMean ± SD | \n
---|---|---|
≤200 | \n378 (28.1) | \n590.4 ± 1105.5 | \n
201–400 | \n428 (31.8) | \n|
401–600 | \n256 (19.0) | \n|
≥601 | \n284 (21.1) | \n
Decoction types of THMs prescribed in TKM clinics.
THM: Traditional herbal medicine
TKM: Traditional Korean medicine
Out of the total 1346 respondents, 1070 TKM doctors prescribed non-decoction types of THMs. The average of prescription cases was 1775.9 ± 2349.1 non-decoction types of THMs/year, and prescription distribution was as follows: 222 (20.7%) had ≤200 cases, 120 (11.2%) had 201–400 cases, 92 (8.6%) had 401–600 cases, and 636 (59.4%) had ≥601 cases (Table 4).
\nPrescription frequency | \nN (%) | \nMean ± SD | \n
---|---|---|
≤200 | \n222 (20.7) | \n1775.9 ± 2349.1 | \n
201–400 | \n120 (11.2) | \n|
401–600 | \n92 (8.6) | \n|
≥601 | \n636 (59.4) | \n
Non-decoction types of THMs prescribed in TKM clinics.
THM: Traditional herbal medicine
TKM: Traditional Korean medicine
Decoction types of THMs have been prescribed in the TKM clinics for various reasons: disease treatment (62.5%), health promotion (21.9%), traffic accidents (8.6%), beauty (5.9%), and others (1.1%). It was found that most TKM clinics prescribe decoction of Korean medicine herbs for treatment of diseases, as shown in Table 5.
\nPrescription purpose | \nMean ± SD | \n
---|---|
Disease treatment | \n62.5 ± 24.7 | \n
Health improvement | \n21.9 ± 19.6 | \n
Traffic accidents | \n8.6 ± 12.5 | \n
Beauty | \n5.9 ± 12.5 | \n
Others | \n1.1 ± 4.6 | \n
Purpose of prescribed decoction types of THMs.
THM: Traditional herbal medicine
Same as above, non-decoction types of THMs have been prescribed for several reasons: disease treatment (89.0%), health promotion (6.0%), car accidents (2.8%), beauty (1.4%), and others (0.9%), as shown in Table 6.
\nPurpose of prescription | \nMean ± SD | \n
---|---|
Disease treatment | \n89.0 ± 19.3 | \n
Health improvement | \n6.0 ± 13.3 | \n
Beauty | \n2.8 ± 6.5 | \n
Traffic accidents | \n1.4 ± 9.1 | \n
Others | \n0.9 ± 5.1 | \n
Purpose of prescribed non-decoction types of THMs.
THM: Traditional herbal medicine
The decoction types of THMs were prescribed for patients suffering from musculoskeletal diseases (56.0%), digestive diseases (21.3%), respiratory diseases (6.3%), and obstetrics and gynecology disease (4.2%).
\nResults showed that decoction types of THMs frequently used for musculoskeletal diseases were Ojeoksan (22.5%), Bojungikgitang (10.3%), and Sipjeondaebotang (7.5%); for digestive diseases were Bojungikgitang (12.5%), Sipjeondaebotang (8.8%), and Ojeoksan (8.8%); for respiratory diseases were Bojungikgitang (9.9%), Socheongryongtang (9.9%), Sipjeondaebotang (8.6%), and Ojeoksan (8.6%); for obstetrics and gynecology diseases were Jogyeongjongogtang (11.1%), Ojeoksan (9.3%), and Bojungikgitang (7.4%); for skin diseases (n = 38) were Ojeoksan (10.5%) and Bojungikgitang (7.9%); for neurological diseases were Ojeoksan (16.7%), Galgeuntang (8.3%), and Yukmijihwangtang (8.3%); for cerebrovascular diseases were Ojeoksan (18.8%), Ganghwangyupungtang (12.5%), and Sipjeondaebotang (9.4%); for mental diseases were Gamiondamtang (11.5%), Kwibitang (7.7%), Bunsimgieum (7.7%), and Ojeoksan (7.7%); for cardiovascular diseases was Gamiondamtang (30.0%); for endocrine diseases was Sipjeondaebotang (25.0%); for urogenital diseases were Ssanghwatang (33.3%), Ojeoksan (33.3%), and Yukmijihwangtang (33.3%); for diseases in eyes and ears was Ojeoksan (100.0%); and for cancer was Banhasasimtang (100.0%), as shown in Table 7.
\nTypes of diseases | \nTop 3 used THMs | \nN (%) | \n
---|---|---|
Musculoskeletal disease (n = 716) | \nOjeoksan (五積散) | \n161 (22.5) | \n
Bojungikgitang (補中益氣湯) | \n74 (10.3) | \n|
Sipjeondaebotang (十全大補湯) | \n54 (7.5) | \n|
Digestive disease (n = 272) | \nBojungikgitang (補中益氣湯) | \n34 (12.5) | \n
Sipjeondaebotang (十全大補湯) Ojeoksan (五積散) | \n24 (8.8) | \n|
Respiratory disease (n = 81) | \nBojungikgitang (補中益氣湯) Socheongryongtang (小靑龍湯) | \n8 (9.9) | \n
Sipjeondaebotang (十全大補湯) Ojeoksan (五積散) | \n7 (8.6) | \n|
Obstetrics and gynecology disease (n = 54) | \nJogyeongjongogtang (調經種玉湯) | \n6 (11.1) | \n
Ojeoksan (五積散) | \n5 (9.3) | \n|
Bojungikgitang (補中益氣湯) | \n4 (7.4) | \n|
Skin disease (n = 38) | \nOjeoksan (五積散) | \n4 (10.5) | \n
Bojungikgitang (補中益氣湯) | \n3 (7.9) | \n|
Dangguisusan (當歸鬚散) Wolbitang (越婢湯) Hwangryunhaedoktang (黃蓮解毒湯) | \n2 (5.3) | \n|
Neurological disease (n = 36) | \nOjeoksan (五積散) | \n6 (16.7) | \n
Galgeuntang (葛根湯) Yukmijihwangtang (六味地黃湯) | \n3 (8.3) | \n|
Cerebrovascular disease (n = 32) | \nOjeoksan (五積散) | \n6 (18.8) | \n
Ganghwangyupungtang (羌活愈風湯) | \n4 (12.5) | \n|
Sipjeondaebotang (十全大補湯) | \n3 (9.4) | \n|
Mental disease (n = 26) | \nGamiondamtang (加味溫膽湯) | \n3 (11.5) | \n
Kwibitang (歸脾湯) Bunsimgieum (分心氣飮) Ojeoksan (五積散) | \n2 (7.7) | \n|
Cardiovascular disease (n = 10) | \nGamiondamtang (加味溫膽湯) | \n3 (30.0) | \n
Ganghwangyupungtang (羌活愈風湯) Bojungikgitang (補中益氣湯) Sipjeondaebotang (十全大補湯) Ojeoksan (五積散) Yukmijihwangtang (六味地黃湯) Insamnyangyeongtang (人蔘養榮湯) Galgeuntang (葛根湯) | \n1 (10.0) | \n|
Endocrine disease (n = 8) | \nSipjeondaebotang (十全大補湯) | \n2 (25.0) | \n
Gwakhyangjunggisan (藿香正氣散) Banhasasimtang (半夏瀉心湯) Bangpungtongseongsan (防風通聖散) Yukgunjatang (六君子湯) Yukmijihwangtang (六味地黃湯) Palmultang (八物湯) | \n1 (12.5) | \n|
Urogenital disease (n = 3) | \nSsanghwatang (雙和湯) Ojeoksan (五積散) Yukmijihwangtang (六味地黃湯) | \n1 (33.3) | \n
Disease in eyes and ears (n = 1) | \nOjeoksan (五積散) | \n1 (100.0) | \n
Cancer (n = 1) | \nBanhasasimtang (半夏瀉心湯) | \n1 (100.0) | \n
Disease proportions and pattern of prescribed decoction types of THMs.
THM: Traditional herbal medicine
The non-decoction types of THMs were prescribed for patients suffering from musculoskeletal diseases (55.6%), respiratory diseases (20.5%), and digestive diseases (18.1%).
\nResults showed that decoction types of THMs frequently used for musculoskeletal diseases were Ojeoksan (36.5%), Gunghatang (15.6%), and Ijintang (7.6%); for respiratory diseases were Ojeoksan (16.1%), Samsoeum (13.8%), and Socheongryongtang (13.8%); for digestive diseases were Pyeongwisan (19.8%), Ojeoksan (19.3%), and Hyangsapyungwisan (10.9%); for neurological diseases was Socheongryongtang (18.8%); for cerebrovascular diseases were Ojeoksan (27.3%) and Yeongyopaedoksan (18.2%); for cardiovascular diseases was Banhabackchulchunmatang (22.2%); for obstetrics and gynecology diseases was Ojeoksan (25.0%); for skin diseases were Gamisoyosan (20.0%), Gunghatang (20.0%), Ojeoksan (20.0%), Insampaedoksan (20.0%), and Pyeongwisan (20.0%); for mental diseases was Ojeoksan (40.0%); for urogenital diseases were Ojeoksan (66.7%) and Pyeongwisan (33.3%); for endocrine diseases were Gumiganghwaltang (50.0%) and Pyeongwisan (50.0%); for diseases in eyes and ears was Ojeoksan (100.0%); and for cancer (n = 1) was Gunghatang (100.0%), as shown in Table 8.
\nTypes of diseases | \nTop 3 used THMs | \nN (%) | \n
---|---|---|
Musculoskeletal disease (n = 591) | \nOjeoksan (五積散) | \n216 (36.5) | \n
Gunghatang (芎夏湯) | \n92 (15.6) | \n|
Ijintang (二陳湯) | \n45 (7.6) | \n|
Respiratory disease (n = 218) | \nOjeoksan (五積散) | \n35 (16.1) | \n
Samsoeum (蔘蘇飮) | \n30 (13.8) | \n|
Socheongryongtang (小靑龍湯) | \n||
Digestive disease (n = 192) | \nPyeongwisan (平胃散) | \n38 (19.8) | \n
Ojeoksan (五積散) | \n37 (19.3) | \n|
Hyangsapyungwisan (香砂平胃散) | \n21 (10.9) | \n|
Neurological disease (n = 16) | \nSocheongryongtang (小靑龍湯) | \n3 (18.8) | \n
Galgeuntang (葛根湯) | \n2 (12.5) | \n|
Ojeoksan (五積散) | \n||
Gumiganghwaltang (九味羌活湯) | \n||
Samsoeum (蔘蘇飮) | \n||
Pyeongwisan (平胃散) | \n||
Cerebrovascular disease (n = 11) | \nOjeoksan (五積散) | \n3 (27.3) | \n
Yeongyopaedoksan (蓮翹敗毒散) | \n2 (18.2) | \n|
Gunghatang (芎夏湯) | \n1 (9.1) | \n|
Bojungikgi-tang (補中益氣湯) | \n||
Socheongryongtang (小靑龍湯) | \n||
Ijintang (二陳湯) | \n||
Jaeumganghwatang (滋陰降火湯) | \n||
Pyeongwisan (平胃散) | \n||
Cardiovascular disease (n = 9) | \nBanhabackchulchunmatang (半夏白朮天麻湯) | \n2 (22.2) | \n
Gumiganghwaltang (九味羌活湯) | \n1 (11.1) | \n|
Gunghatang (芎夏湯) | \n||
Bojungikgitang (補中益氣湯) | \n||
Sosihotang (小柴胡湯) | \n||
Ijungtang (理中湯) | \n||
Ijintang (二陳湯) | \n||
Pyeongwisan (平胃散) | \n||
Obstetrics and gynecology disease (n = 8) | \nOjeoksan (五積散) | \n2 (25.0) | \n
Gamisoyosan (加味逍遙散) | \n1 (12.5) | \n|
Gunghatang (芎夏湯) | \n||
Bulhwangeumjeonggisan (不換金正氣散) | \n||
Samsoeum (蔘蘇飮) | \n||
Ijintang (二陳湯) | \n||
Pyeongwisan (平胃散) | \n||
Skin disease (n = 5) | \nGamisoyosan (加味逍遙散) | \n1 (20.0) | \n
Gunghatang (芎夏湯) | \n||
Ojeoksan (五積散) | \n||
Insampaedoksan (人蔘敗毒散) | \n||
Pyeongwisan (平胃散) | \n||
Mental disease (n = 5) | \nOjeoksan (五積散) | \n2 (40.0) | \n
Gamisoyosan (加味逍遙散) | \n1 (20.0) | \n|
Gumiganghwaltang (九味羌活湯) | \n||
Daecheongnyongtang (大靑龍湯) | \n||
Urogenital disease (n = 3) | \nOjeoksan (五積散) | \n2 (66.7) | \n
Pyeongwisan (平胃散) | \n1 (33.3) | \n|
Endocrine disease (n = 2) | \nGumiganghwaltang (九味羌活湯) | \n1 (50.0) | \n
Pyeongwisan (平胃散) | \n||
Disease in eyes and ears (n = 1) | \nOjeoksan (五積散) | \n1 (100.0) | \n
Cancer (n = 1) | \nGunghatang (芎夏湯) | \n1 (100.0) | \n
Disease proportions and pattern of prescribed non-decoction types of THMs.
THM: Traditional herbal medicine
This study investigated the use of THMs in TKM clinics in South Korea.
\nResults showed that average prescription cases of 590.4 ± 1105.5 decoction types of THMs and 1775.9 ± 2349.1 non-decoction types of THMs had been prescribed by doctors per year in the TKM clinics. According to the Korean national survey [27], the use of decoction types of THMs was 54.8%, and non-decoction types of THMs with the exception of insurance herbal extracts was 45.2% [27].
\nThe reason for the preference for decoction types of THMs in South Korea is that the traditional way to boil herbs is familiar to the people, and it is possible to prescribe customized prescription according to the symptoms of the patients [31]. Non-decoction types of THMs such as granule, pill, tablet, soft extract, paste, and powder are convenient to store and carry because it is smaller in size than the decoction types of THMs [27]. In the case of the same prescription, the non-decoction types of THMs found to be cheaper than decoction types of THMs, so that patients may prefer non-decoction types of THMs for economic reason [27].
\nAccording to the 2017 national survey, Koreans responded that decoction types of THMs were too expensive (44.3%) and required health insurance coverage with a top priority (55.2%) [27]. This point will be solved soon since the Korean MHW has a plan to conduct a pilot program for insurance coverage expansion to the THMs in the latter half of 2019 [32].
\nThe Korean MHW has a plan to conduct a pilot program for insurance coverage expansion to the THMs in the latter half of 2019 [32]. This point will make decoction types of THMs more affordable; this is mainly because the decoction type is found to be more potent and used in a wide range than the non-decoction type. As mentioned by Yoo and Son [33], unlike the non-decoction types of THMs, which were mostly used for therapeutic purposes (89.0%), the decoction types of THMs were not only used for the purpose of treatment of diseases (62.5%) but also for health improvement purposes (21.9%). THMs, especially decoction types of THMs, have played an important role in the prevention of diseases and health promotion in people in South Korea [33]. It is related to the viewpoint of TKM, which improves the vitality by correcting the imbalance of the human body, and the traditional way of boiling herbs reflects this [33].
\nIn respiratory diseases, non-decoction types of THMs (20.5%) were more frequently prescribed than decoction types of THMs (6.3%). It is important to take the medication early during a cold, because of the need to combat the virus. It relieves symptoms such as cough, nasal congestion, and rhinorrhea [34]. The decoction types of THMs require about 1 day of preparation time because it takes time to boil the mixed herbs. In the case of non-decoction types of THMs, it is presumed that it is used in respiratory diseases such as cold, because it can be prepared in advance, or ready-made products (pharmaceutical products) can be prescribed immediately.
\nKoreans suffer from digestive diseases due to the preference of spicy and salty Foods, and frequent use of antibiotics [35, 36]. In general, decoction types of THMs are used for treating digestive diseases [27]. The reason for using decoction types of THMs for treating digestive diseases is related to drug manufacturing method and patient’s digestive condition [37]. As a result of that, decoction types of THMs seem to be more preferable and suitable for digestive diseases [27, 37].
\nThere are several limitations in this study. First, some data were limited or deficient due to their limited sources, and the information may be biased despite our efforts to obtain objective data. Since this study was particularly purposed to identify the prescription of THMs for each disease, there is a limitation to the analysis by excluding “other” diseases.
\nSecond, we could not analyze the results of the use of all Korean THMs because the questionnaire was designed specifically for decoction types of THMs. In addition, we could not assess the utilization status of different THM forms (e.g., granule, pill, tablet, soft extract, paste, and powder) and their target diseases, except for the decoction types of THMs. The dosage has an important influence on the treatment [38]. In order to examine the whole use and status of dosage forms of THMs, the questionnaire needs to be revised in a future survey.
\nThird, we investigated the disease categories, not the specific diseases that THMs were prescribed for. In the 2020 national survey, the questionnaire needs to be corrected so that the respondents can reply in regard to specific diseases.
\nOur study, based on a national survey of TKM doctors, presented the overall status of medical use of THMs in South Korea. However, the 2017 national survey was conducted separately for decoction and non-decoction types of THMs. Therefore, we could not assess the whole status of THM usage and therapeutic effects of each THM formulation. In future survey, we hope to be able to assess the details of medical use of THMs in South Korea.
\nThis work was supported by the Policy Support Project for the Development of Traditional Korean Medicine funded by the Ministry of Health and Welfare.
\nThe authors declare no conflict of interest.
THM | Traditional herbal medicine |
TM | Traditional medicine |
TKM | Traditional Korean medicine |
MFDS | Ministry of Food and Drug Safety |
MHW | Ministry of Health and Welfare |
IntechOpen implements a robust policy to minimize and deal with instances of fraud or misconduct. As part of our general commitment to transparency and openness, and in order to maintain high scientific standards, we have a well-defined editorial policy regarding Retractions and Corrections.
",metaTitle:"Retraction and Correction Policy",metaDescription:"Retraction and Correction Policy",metaKeywords:null,canonicalURL:"/page/retraction-and-correction-policy",contentRaw:'[{"type":"htmlEditorComponent","content":"IntechOpen’s Retraction and Correction Policy has been developed in accordance with the Committee on Publication Ethics (COPE) publication guidelines relating to scientific misconduct and research ethics:
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\\n\\nIntechOpen wishes to emphasize that the final decision on whether a Retraction, Statement of Concern, or a Correction will be issued rests with the Academic Editor. The publisher is obliged to act upon any reports of scientific misconduct in its publications and to make a reasonable effort to facilitate any subsequent investigation of such claims.
\\n\\nIn the case of Retraction or removal of the Work, the publisher will be under no obligation to refund the APC.
\\n\\nThe general principles set out above apply to Retractions and Corrections issued in all IntechOpen publications.
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\\n\\nPolicy last updated: 2017-09-11
\\n"}]'},components:[{type:"htmlEditorComponent",content:'IntechOpen’s Retraction and Correction Policy has been developed in accordance with the Committee on Publication Ethics (COPE) publication guidelines relating to scientific misconduct and research ethics:
\n\n1. RETRACTIONS
\n\nA Retraction of a Chapter will be issued by the Academic Editor, either following an Author’s request to do so or when there is a 3rd party report of scientific misconduct. Upon receipt of a report by a 3rd party, the Academic Editor will investigate any allegations of scientific misconduct, working in cooperation with the Author(s) and their institution(s).
\n\nA formal Retraction will be issued when there is clear and conclusive evidence of any of the following:
\n\nPublishing of a Retraction Notice will adhere to the following guidelines:
\n\n1.2. REMOVALS AND CANCELLATIONS
\n\n2. STATEMENTS OF CONCERN
\n\nA Statement of Concern detailing alleged misconduct will be issued by the Academic Editor or publisher following a 3rd party report of scientific misconduct when:
\n\nIntechOpen believes that the number of occasions on which a Statement of Concern is issued will be very few in number. In all cases when such a decision has been taken by the Academic Editor the decision will be reviewed by another editor to whom the author can make representations.
\n\n3. CORRECTIONS
\n\nA Correction will be issued by the Academic Editor when:
\n\n3.1. ERRATUM
\n\nAn Erratum will be issued by the Academic Editor when it is determined that a mistake in a Chapter originates from the production process handled by the publisher.
\n\nA published Erratum will adhere to the Retraction Notice publishing guidelines outlined above.
\n\n3.2. CORRIGENDUM
\n\nA Corrigendum will be issued by the Academic Editor when it is determined that a mistake in a Chapter is a result of an Author’s miscalculation or oversight. A published Corrigendum will adhere to the Retraction Notice publishing guidelines outlined above.
\n\n4. FINAL REMARKS
\n\nIntechOpen wishes to emphasize that the final decision on whether a Retraction, Statement of Concern, or a Correction will be issued rests with the Academic Editor. The publisher is obliged to act upon any reports of scientific misconduct in its publications and to make a reasonable effort to facilitate any subsequent investigation of such claims.
\n\nIn the case of Retraction or removal of the Work, the publisher will be under no obligation to refund the APC.
\n\nThe general principles set out above apply to Retractions and Corrections issued in all IntechOpen publications.
\n\nAny suggestions or comments on this Policy are welcome and may be sent to permissions@intechopen.com.
\n\nPolicy last updated: 2017-09-11
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