Chapters authored
Anticancer Effect of Capsaicin and Its Analogues
Potent biomolecules from natural products from plants, animals, and minerals are the fundamental basis of the ailment of mankind. Capsicum or red pepper plants were grouped under the kingdom Plantae and family Solanaceae. It is used widely throughout the world in foods for their pungent flavor and aroma, and to prolong food spoilage. This chapter presents a frame of a concise compilation of the anticancer and cytotoxic potentials of Capsicum, its analogs, and related compounds. Capsaicin (trans-8-methyl-N-vanillyl-6-nonenamide) is the most predominant and naturally occurring alkaloid from the Capsicum species. It also details the anticancer efficacy of capsaicin and its analogs like capsaicinoids and capsiates which possess antioxidants and targets multiple signaling pathways, ontogenesis, and tumor-suppressor genes in various types of cancer models. Capsaicin is a major ingredient and has been linked to suppression of growth in various cancer cells. The data available strongly indicate the significant anticancer benefits of capsaicin and its potent analog molecules. It shows a significant effect on cancer cell proliferation, apoptosis, cancer cell surveillance, growth arrest, and metastasis. This chapter also predominantly focuses on the combinational use of capsaicin with other natural dietary compounds as a measure of synergistic anticancer activities.
Part of the book: Capsicum
Dengue Fever: An Overview
Dengue fever is a disease caused by a family of viruses transmitted by mosquitoes. Dengue virus (DENV), a member of the Flaviviridae family, causes the most widespread mosquito-borne viral infection in humans around the world today. Dengue can affect anyone but tends to be more severe in people with compromised immune systems. Dengue hemorrhagic fever is a more severe form of a viral illness. Symptoms include headache, fever, rash, and evidence of bleeding (hemorrhage) in the body. This form of dengue fever can be life-threatening and can progress to the most severe form of the illness, dengue shock syndrome. This chapter reviews the etiology, epidemiology, diagnosis, pathophysiology, transmissions, manifestations, diagnosis, treatment, and prevention of dengue.
Part of the book: Dengue Fever in a One Health Perspective