Monica Fedele

National Research Council Italy

Monica Fedele (Naples, 03/23/69) received her Ph.D. in Cellular and Molecular Biology and Pathology at the Medical School of the University of Naples Federico II, Italy, working in the laboratory of Alfredo Fusco. Then, she was a postdoctoral investigator in the laboratory of Carlo M. Croce, at the Kimmel Cancer Institute in Philadelphia, USA, focusing on the development of transgenic and knockout mice for the HMGA and other related genes. Now she is a group leader at the Istituto di Endocrinologia e Oncologia Sperimentale (IEOS) of the National Council of the Research (CNR) in Italy and her main interest is the role of chromatinic proteins in cancer. Her main scientific achievements are the isolation and characterization of the putative tumor suppressor gene PATZ, the demonstration of the oncogenic activity of the chromatinic proteins HMGA1 and HMGA2 in vitro and in vivo, and the discovery of their critical role in the development of pituitary adenomas.

Monica Fedele

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Latest work with IntechOpen by Monica Fedele

This book covers a selected number of hot topics in endocrine and hormone-related pathologies, discussed by eminent scientists and clinicians coming from different countries of the world. It deals with advanced recent trends in the field, including neuroendocrine and pituitary tumors, thyroid dysfunctions, diabetes and a series of endocrine-related diseases, such as those related to the anabolic effects of testosterone, obesity, cancer, the liver complications of diabetes and the pediatric nonalcoholic fatty liver disease. The readers should be able to have a basic, as well as critic and advanced, overview of these selected hot pathologies of the endocrine system.

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