In-Ga-Zn-O-TFT differential amplifier comparison.
\\n\\n
Released this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\\n\\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
\\n"}]',published:!0,mainMedia:{caption:"Highly Cited",originalUrl:"/media/original/117"}},components:[{type:"htmlEditorComponent",content:'IntechOpen is proud to announce that 191 of our authors have made the Clarivate™ Highly Cited Researchers List for 2020, ranking them among the top 1% most-cited.
\n\nThroughout the years, the list has named a total of 261 IntechOpen authors as Highly Cited. Of those researchers, 69 have been featured on the list multiple times.
\n\n\n\nReleased this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\n\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
\n'}],latestNews:[{slug:"intechopen-supports-asapbio-s-new-initiative-publish-your-reviews-20220729",title:"IntechOpen Supports ASAPbio’s New Initiative Publish Your Reviews"},{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"}]},book:{item:{type:"book",id:"465",leadTitle:null,fullTitle:"Carbon Nanotubes Applications on Electron Devices",title:"Carbon Nanotubes",subtitle:"Applications on Electron Devices",reviewType:"peer-reviewed",abstract:"Carbon nanotubes (CNTs), discovered in 1991, have been a subject of intensive research for a wide range of applications. In the past decades, although carbon nanotubes have undergone massive research, considering the success of silicon, it has, nonetheless, been difficult to appreciate the potential influence of carbon nanotubes in current technology. The main objective of this book is therefore to give a wide variety of possible applications of carbon nanotubes in many industries related to electron device technology. This should allow the user to better appreciate the potential of these innovating nanometer sized materials. Readers of this book should have a good background on electron devices and semiconductor device physics as this book presents excellent results on possible device applications of carbon nanotubes. This book begins with an analysis on fabrication techniques, followed by a study on current models, and it presents a significant amount of work on different devices and applications available to current technology.",isbn:null,printIsbn:"978-953-307-496-2",pdfIsbn:"978-953-51-4465-6",doi:"10.5772/977",price:159,priceEur:175,priceUsd:205,slug:"carbon-nanotubes-applications-on-electron-devices",numberOfPages:572,isOpenForSubmission:!1,isInWos:1,isInBkci:!0,hash:null,bookSignature:"Jose Mauricio Marulanda",publishedDate:"August 1st 2011",coverURL:"https://cdn.intechopen.com/books/images_new/465.jpg",numberOfDownloads:101717,numberOfWosCitations:113,numberOfCrossrefCitations:86,numberOfCrossrefCitationsByBook:14,numberOfDimensionsCitations:118,numberOfDimensionsCitationsByBook:17,hasAltmetrics:1,numberOfTotalCitations:317,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"October 12th 2010",dateEndSecondStepPublish:"November 9th 2010",dateEndThirdStepPublish:"March 16th 2011",dateEndFourthStepPublish:"April 15th 2011",dateEndFifthStepPublish:"June 14th 2011",currentStepOfPublishingProcess:5,indexedIn:"1,2,3,4,5,6,7,8",editedByType:"Edited by",kuFlag:!1,featuredMarkup:null,editors:[{id:"9142",title:"Prof.",name:"Jose Mauricio",middleName:null,surname:"Marulanda",slug:"jose-mauricio-marulanda",fullName:"Jose Mauricio Marulanda",profilePictureURL:"https://mts.intechopen.com/storage/users/9142/images/1746_n.jpg",biography:"Jose Mauricio Marulanda has a Doctor of Philosophy in Electrical Engineering from Louisiana State University. He has a Masters and a Bachelor of Science in Electrical Engineering as well. He is currently working as a Senior Hardware Engineer for the Research and Development Center at ABB, Inc. At ABB, he currently conducts research in the area of Electromagnetic Compatibility (EMC). His areas of expertise are Computer Aided Design, VLSI, integrated circuit modeling and design. He has experience with system level validation by qualifying products to be released into the market with zero defects. He has an extensive academic and research experience in VLSI, MOS and bipolar devices, semiconductor device physics, device modeling and carbon nanotubes. His work in carbon nanotubes includes generating models for the electron transport in carbon nanotubes and their implementation as field effect transistors, logic gates, biosensors and interconnects. 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to examine the Kalman Filter (KF), also known as the Kalman Bucy Filter (KBF), from the standpoint of its engineering implementation. The intended purpose of the book will be to extend the circle of users of the Kalman filter by considering it not as a means of theoretical analysis, but rather as a powerful tool for the design of a technical system. The editor accumulated experience of using suboptimal KF in various aerospace applications and would wish to share it with the pool of potential users and like-minded specialists. Instead of the formal programming of the recursive KF equations some simple and robust sub-optimal forms are proposed. For example, developed by the editor, suboptimal (KBF), with bounded grows of memory (FBGM) and its steady-state form- the time-invariant filter with constant coefficients is aimed to be considered. This allows the developer to use the KBF not only for system state estimation but for control as well. Proceeding in this way developer can be guaranteed the filter stability and robustness in many practically uncertain situations when the statistic characteristics of system disturbances and measured errors are not entirely known. A guaranteed approach with using an equivalent white noise is also aimed to be considered. Some representative examples from typical aerospace systems (the editor’s main professional field) are intended to be presented. Summarizing the above, it can be emphasized that when implementing the KF it is always useful to replace the art of programming with the experience of designing conventional robust systems having an idealistic estimate of maximum (best) of achievable performance. This would prevent the system's real-time computer from many possible situations with “empty “computations and even to the divergence of the computational process. It can also show that the filter is not a magic mill and cannot achieve the desired performance if it cannot be achieved in principle, better that it can be “promised” by the KF quadratic criterion minimum, or if some state vector components are not observable and controllable.
",isbn:"978-1-80356-576-7",printIsbn:"978-1-80356-575-0",pdfIsbn:"978-1-80356-577-4",doi:null,price:0,priceEur:0,priceUsd:0,slug:null,numberOfPages:0,isOpenForSubmission:!1,isSalesforceBook:!1,isNomenclature:!1,hash:"4c3e68adcaeaa44f9fbfe9bb19bdd55b",bookSignature:"Dr. Yuri Kim",publishedDate:null,coverURL:"https://cdn.intechopen.com/books/images_new/11504.jpg",keywords:"Separation Theorem, Extended Kalman Filter, Covariance Matrix, Riccati Equation, FBGM, Analytical Implementation Forms, Physical Implementation Forms, Steady State Filter, Inertial Navigation System, Global Positioning System, Controllability, Multisensory Navigation",numberOfDownloads:null,numberOfWosCitations:0,numberOfCrossrefCitations:null,numberOfDimensionsCitations:null,numberOfTotalCitations:null,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"March 15th 2022",dateEndSecondStepPublish:"June 2nd 2022",dateEndThirdStepPublish:"August 1st 2022",dateEndFourthStepPublish:"October 20th 2022",dateEndFifthStepPublish:"December 19th 2022",dateConfirmationOfParticipation:null,remainingDaysToSecondStep:"3 months",secondStepPassed:!0,areRegistrationsClosed:!0,currentStepOfPublishingProcess:4,editedByType:null,kuFlag:!1,biosketch:"Prof. Y.V. Kim is a Doctor of Technical Science, having a broad and wealthy international scientific, engineering, and teaching experience, obtained in the former USSR, Israel, and Canada. He has many scientific publications and implemented inventions dedicated to Aerospace GN&C.",coeditorOneBiosketch:null,coeditorTwoBiosketch:null,coeditorThreeBiosketch:null,coeditorFourBiosketch:null,coeditorFiveBiosketch:null,editors:[{id:"316140",title:"Dr.",name:"Yuri",middleName:null,surname:"Kim",slug:"yuri-kim",fullName:"Yuri Kim",profilePictureURL:"https://mts.intechopen.com/storage/users/316140/images/system/316140.jpg",biography:"Yuri Kim\n24 Buttenut, Gatineau, QC, Canada\nTel : 1-(514)- 466-1033, e-mail: yurikim@hotmail.ca\n\nHIGHLIGHTS OF QUALIFICATIONS:\n\nExperienced scientist, engineer and manager with internationally recognized achievements in area of Aerospace Avionics, (GN&C); Analysis, design (HW&SW), integration, testing and operation for various aerospace platforms and missions. \n\nGained a broad experience in preparation of technical documents for Joint (Industry-Customer) State Commissions for the acceptance (commissioning) of Aerospace Avionics, Navigation and Special application experimental equipment for further serial production, and operational support. Last works have been dedicated to R&D projects developing new Satellite Navigation Control Technology and customer support of Canadian satellites Control system design.\n\n\nACADEMIC DEGREES:\n\n 1991 *Doctor of Technical Science Diploma in Aerospace Vehicles Guidance \n Navigation and Control \n Scientific Council of State Institute of Automatic Systems, Ministry of Aviation\n Industry of USSR, Moscow\n (Recognized by Canadian Professional Counsel of Engineers) \n1982 * Senior Scientific Fellow Diploma in Gyroscopes and Navigation systems \n Capital Certification Commission of Scientists, Ministry of High Education of\n USSR, Moscow.\n (Recognized by Canadian Professional Counsel of Engineers)\n1974 * Candidate of Technical Science Diploma in Aerospace Navigation\n and Control Systems (Accredited as Ph.D by York University, Toronto.)\n Scientific Council of Moscow Aviation Institute, Moscow.\n1970 * Engineer Electromechanic Diploma in Gyro and Navigation systems,\n Faculty of Flight Apparatuses Control Systems, Moscow Aviation Institute, \n Moscow (Accredited as between Masters Degree and Bachelor Degree by\n York University, Toronto).\n1965 * Radio and TV Systems Technician Certificate, Dnepropetrovsk Technical School \n of preparation of technical specialists for Soviet Army, Military Aviation and \n Navy.\n\nMILITARY EDUCATION:\n\n1970 * Engineer in ballistic rocket control system, Military Faculty of MAI, last rank senior engineer-lieutenant (in reserve)\n\n\n\nEMPLOYMENT HISTORY:\nA. GOVERNMENT\n\nAt present - Canadian Space Agency, Space Science and Technology Division, David Florida Laboratory\n\n Senior Aerospace System engineer \n\n° Performing, developing and supporting phases of design, testing, commissioning and \n operation for space vehicle orbit and attitude control systems, in particular: Tecsas, Scope, \n J2Sat, Small satellite, M3Msat, Cassiopea, Neossat, RCM, PCW\n\n° Reviewing and commenting on Attitude Control systems design documentations, related to \n all phases of system development commissioning and operation\n \n° Supporting Aerospace Industry R&D projects funding by CSA (STDP) as Scientific\n Authority, in particular: Microwheel (Dynacon), LOCOOS (NGC), PCW (Bristol)\n\n° Providing expertise on new initiatives for Space Exploration and Utilization regarding \n Attitude and Orbital Control and possible development of Canadian space launcher\n\n° Developing basic mathematical (Simulink/Matlab) simulator for developing the \n requirements and expected performance of AODCS for new space vehicles\n\n° Developing new basic technology (based on Kalman Filter) for satellite attitude\n determination and sensor calibration, developing of FF test-bed equipment and GPS \n navigation in environment of CSA laboratory, developing of methods of ACS sensors\n calibration, measuring and compensation of satellite residual magnetic moment, experimental determination of satellite inertia matrix during ACS integration tests\n\n° Interacting with Space Industry and Universities in the problems, related to development of \n new methods and systems for space vehicle attitude and orbit determination and control\n \n° Sharing with International Aerospace community CSA achievements and experience in\n development of new technologies and methods for space vehicle attitude and orbit \n determination and control through publications, presentations and participation in scientific\n conferences, meetings and symposiums as well as maintaining an awareness about new \n technological advancements\n \n° Providing professional training for students and post. Graduates in the area of Orbital and\n Attitude Dynamic and Control\n\nB. INDUSTRIAL\n\nSept. 1998 – Feb. 1999 – Olympia Engineering Ltd. (Toronto)\n\nResearch and Development Engineer\n\n•\tDevelopment of measuring instrument for measuring remote measuring of micro- deformations of machinery (milling machine) equipment\n•\tResearch and testing of differential GPS survey equipment and antennas in environment of industrial facility for developing a new remote method for the measuring of machinery micro-deformations\n\n\n\n\nFeb.1999 – Jun.2002 – Saskatoon Engineering Division of Calian Company, \n Radarsat-1 Operation Team (CSA, Montreal)\n\nAttitude Control System Analyst\n\n•\tWorking as RADARSAT-1 Attitude Control System Analyst performing day-to-day operation TLM data analysis; reporting, monitoring and solving ACS flight anomaly problems, maintaining ACS software and performance \n•\tAuthor of many reports (see attached list of publications), devoted to solving of Radarsat-1 non-benign Safe Hold Mode problem, Momentum Wheel failure problems and improvement of the performance of attitude determination method with Magnetometer and Sun Sensor (back up, ADM3 mode for the case of potential failure of Horizon Scanner).\n•\tPreparation and implementation of the solution for RADARSAT-1 operation without failed Momentum Wheels, that saved the satellite mission after the wheel failures\n(This work was prolonged after in CSA and awarded by the Canadian Government Award for the invention used by the Government)\n•\tDesign and implementation of new dynamic simulators (based on Simulink\ntoolbox) for Radarsat-1 ACS for operation support\n•\tPreparation for operation of new Canadian satellites Scisat and RADARSAT-2 \n\n\n\nJan. 1994 – Sep. 1997 – Israel Aviation Industry (IAI factories: TASHAN, LAHAV)\n\nAvionics system engineer\n\n•\tResearch and preliminary design of the Special Data Fusion System for a fighter-interceptor\n•\tIntegration of Inertial Navigation System with Global Position System into Upgraded Avionics Suit and installation in aircraft cockpit for A/C – trainer T-38\n\nNov. 1977 – Apr. 1993 – Moscow Research and Design Institute of Electromechanic and Automatic (formerly P/B: M5537, presently “Aviapribor” Corporation)\n\n \nHead of Division (R&D in Pilot-Navigation Systems)\n\n•\tLeadership of the Division, performing planning, financial and methodological duties, related to this position, reporting to the R&D deputy director of the Institute\n•\tResponsibility for Pilot-Navigation System integration, interaction, tests and transferring for serial production and operational support\n•\tInitiation and methodical leadership of innovative research and development projects\n•\tReviewing, commenting and implementation of Technical standards and Navigation norms\nas well as sharing progressive methods and results within Aerospace organizations within former USSR\n \n Head of Department (INS and Flight Management System SW Development)\n\n•\tLeadership and performing of duties of Head of Department \n•\tResponsibility for the prospective research and preliminary design of the Inertial Navigation Systems (INS) and Flight Management Systems (FMS)\n•\tDesign of the INS and FMS algorithms and simulation of expected performance\n•\tDevelopment of INS/FMS flight code\n•\tDevelopment of test procedures and simulators for FMS, and pilot nav.complexis for aircrafts \n•\tResponsibility for system performance analysis in the ground and flight tests\n\n Head of Sector (System Flight Test data analysis) \n\n•\tLeadership of the Sector\n•\tDevelopment of ground and flight test simulation procedures and requirements for test equipment and simulators, for flight test aircraft measuring equipment, installation and recorded data processing\n•\tDesign of Estimation and Identification algorithms for ground and flight data processing\n•\tTest data analysis, preparation of test results analysis reports and conclusions\n\n Senior Scientific Fellow\n\n•\tResearch, development and principal design of the special Suboptimal Kalman Filter for the fusion of data of various navigation sensors for aviation and space platforms\n•\tDevelopment of new Guidance and Navigation methods for aviation and space platforms\n•\tAnalysis of INS and FMS performance in ground and flight tests\n\nC. ACADEMIC \n\n1977–1993 – Moscow Aviation Institute, Moscow Institute of Instrument -\n Making, Aviation Industry Ministry Upgrade Qualification Institute\n(Part Time) Professor, Associate professor, Chairmen of State Diploma Commission,\n Member of Scientific Council\n•\tLecturer of the disciplines: Applied Oscillation, Theory (MIIM), Design of Instruments (MIIM), Integrated Navigation Systems (MUQI)\n•\tChairman of the State Diploma Commission -Gyro Instruments and Systems (MAI)\n•\tLeadership of postgraduates, participation in sessions of Scientific Council (MAI)\n•\tMethodical management of cathedra of Orientation and Navigation in MAI \n\n2009 McGill University, Montreal\n\nPart time lecturer for course (in English): Aircraft Performance, Stability and Control\n\n1970–1977 – Moscow Aviation Institute \n(Full Time) Associate Professor, Senior Researcher, Assistant Lecturer \n•\tLecturer of the courses: Spacecraft orbital mechanics and attitude determination and control, Inertial Navigation Systems, Gyro Instruments and Systems\n•\tResearch and development of suboptimal robust estimation methods for navigation data processing\n•\tResponsibility for the navigation systems laboratory\n•\tDeputy head of cathedra of Orientation and Navigation\n\nFIELDS OF THEORETICAL AND METHODOLOGIC EXPERTISE:\n \n•\tSpace vehicle Orbit and Attitude determination and control\n•\tGyro instruments and systems\n•\tRadio navigation systems\n•\tInertial Navigation systems\n•\tAirplane Navigation and Control\n•\tAnalytical mechanics \n•\tApplied oscillation theory\n•\tAutomatic control theory\n•\tStochastic estimation theory\n\nENGINEERING EXPERIENCE:\n\n•\tFlight and laboratory tests of Aerospace Avionics Equipment\n•\tDistribution of mission requirements between Aerospace vehicle subsystems, definition of functions and ICD \n•\tSpacecraft operation and performance maintenance\n•\tAvionics system (hardware and software) development and testing (autonomously and integration)\n•\tInertial navigation systems\n•\t Development of Avionics for Soviet Military aircrafts: Tu-142, Tu-95MC, An-124, An-70, A-40, Soviet Space shuttle “Buran” (responsibility for preliminary design of radio-navigation automatic landing system), \n•\tIsrael (IAI) upgrade of Avionics system for T-38 (USA Air force trainer) \n•\tOperation and modification in space Canadian Satellite RADARSAT-1 Attitude Control system\n•\tParticipation in commissioning of ACS of Canadian Satellite Scisat\n•\tDevelopment of a generic mathematical simulator for satellite AODCS analysis and simulation of expected performance for a family of Canadian new generation small satellites\n\nSCIENTIFIC EXPERIENCE:\n\n•\tTheoretical and experimental investigation in the fields of S/C Orbital and Attitude Control\n•\tKalman Filter suboptimization and robust guarantee estimation theory development: authorship of new Suboptimal Kalman Filter modification, methods of INS correction and calibration, 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Hiott",authors:[{id:"82511",title:"Dr.",name:"Charlene",middleName:null,surname:"Jackson",fullName:"Charlene Jackson",slug:"charlene-jackson"},{id:"114713",title:"Mr.",name:"John",middleName:null,surname:"Barrett",fullName:"John Barrett",slug:"john-barrett"},{id:"137245",title:"Mrs.",name:"Lori",middleName:null,surname:"Spicer",fullName:"Lori Spicer",slug:"lori-spicer"},{id:"137246",title:"MSc.",name:"Lari",middleName:null,surname:"Hiott",fullName:"Lari Hiott",slug:"lari-hiott"}]},{id:"35103",title:"The Use of Pulsed Field Gel Electrophoresis in Listeria monocytogenes Sub-Typing - Comparison with MLVA Method Coupled with Gel Electrophoresis",slug:"feasibility-of-the-mlva-method-coupled-with-agarose-gel-electrophoresis-for-subtyping-listeria-monoc",signatures:"Sophie Roussel, Marie-Leone Vignaud, Jonass T Larsson, Benjamin Felix, Aurore Rossignol,\r\nEva Moller Nielsen and Anne Brisabois",authors:[{id:"116745",title:"Dr.",name:"Sophie",middleName:null,surname:"Roussel",fullName:"Sophie Roussel",slug:"sophie-roussel"},{id:"118109",title:"Dr.",name:"Benjamin",middleName:null,surname:"Félix",fullName:"Benjamin Félix",slug:"benjamin-felix"}]},{id:"35104",title:"Restriction Fragment Length Polymorphism Analysis of PCR-Amplified Fragments (PCR-RFLP) and Gel Electrophoresis - Valuable Tool for Genotyping and Genetic Fingerprinting",slug:"restriction-fragment-length-polymorphism-analysis-of-pcr-amplified-fragments-pcr-rflp-and-related-te",signatures:"Henrik Berg Rasmussen",authors:[{id:"114068",title:"Dr.",name:"Henrik",middleName:null,surname:"Rasmussen",fullName:"Henrik Rasmussen",slug:"henrik-rasmussen"}]},{id:"35105",title:"Application of Two-Dimensional Gel Electrophoresis to Microbial Systems",slug:"application-of-two-dimensional-gel-electrophoresis-to-microbial-systems",signatures:"Fatemeh Tabandeh, Parvin Shariati and Mahvash Khodabandeh",authors:[{id:"115663",title:"Dr.",name:"Fatemeh",middleName:null,surname:"Tabandeh",fullName:"Fatemeh Tabandeh",slug:"fatemeh-tabandeh"},{id:"118100",title:"Dr.",name:"Parvin",middleName:null,surname:"Shariati",fullName:"Parvin Shariati",slug:"parvin-shariati"},{id:"118101",title:"Dr.",name:"Mahvash",middleName:null,surname:"Khodabandeh",fullName:"Mahvash Khodabandeh",slug:"mahvash-khodabandeh"}]}]}],publishedBooks:[{type:"book",id:"4529",title:"Biotechnology",subtitle:null,isOpenForSubmission:!1,hash:"187f1fe91150e1be30e641799522b977",slug:"biotechnology",bookSignature:"Deniz Ekinci",coverURL:"https://cdn.intechopen.com/books/images_new/4529.jpg",editedByType:"Edited by",editors:[{id:"13652",title:"Prof.",name:"Deniz",surname:"Ekinci",slug:"deniz-ekinci",fullName:"Deniz Ekinci"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"584",title:"Advances in Applied Biotechnology",subtitle:null,isOpenForSubmission:!1,hash:"fcc9fab84b820983f2a462d5145d2a0e",slug:"advances-in-applied-biotechnology",bookSignature:"Marian Petre",coverURL:"https://cdn.intechopen.com/books/images_new/584.jpg",editedByType:"Edited by",editors:[{id:"74654",title:"Prof.",name:"Marian",surname:"Petre",slug:"marian-petre",fullName:"Marian Petre"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1770",title:"Gel Electrophoresis",subtitle:"Principles and Basics",isOpenForSubmission:!1,hash:"279701f6c802cf02deef45103e0611ff",slug:"gel-electrophoresis-principles-and-basics",bookSignature:"Sameh Magdeldin",coverURL:"https://cdn.intechopen.com/books/images_new/1770.jpg",editedByType:"Edited by",editors:[{id:"123648",title:"Dr.",name:"Sameh",surname:"Magdeldin",slug:"sameh-magdeldin",fullName:"Sameh Magdeldin"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1910",title:"Oxidative Stress",subtitle:"Molecular Mechanisms and Biological Effects",isOpenForSubmission:!1,hash:"a5fc01580caefb2637f31d59b377032a",slug:"oxidative-stress-molecular-mechanisms-and-biological-effects",bookSignature:"Volodymyr Lushchak and Halyna M. Semchyshyn",coverURL:"https://cdn.intechopen.com/books/images_new/1910.jpg",editedByType:"Edited by",editors:[{id:"96151",title:"Dr.",name:"Volodymyr",surname:"Lushchak",slug:"volodymyr-lushchak",fullName:"Volodymyr Lushchak"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"2115",title:"Biotechnology",subtitle:"Molecular Studies and Novel Applications for Improved Quality of Human Life",isOpenForSubmission:!1,hash:"07ebd9c0af07dd6b0649bc67ae612b1e",slug:"biotechnology-molecular-studies-and-novel-applications-for-improved-quality-of-human-life",bookSignature:"Reda Helmy Sammour",coverURL:"https://cdn.intechopen.com/books/images_new/2115.jpg",editedByType:"Edited by",editors:[{id:"32232",title:"Dr.",name:"Reda",surname:"Sammour",slug:"reda-sammour",fullName:"Reda Sammour"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],publishedBooksByAuthor:[{type:"book",id:"956",title:"Cystic Fibrosis",subtitle:"Renewed Hopes Through Research",isOpenForSubmission:!1,hash:"703f0969078948d82535b7b0c08ab613",slug:"cystic-fibrosis-renewed-hopes-through-research",bookSignature:"Dinesh Sriramulu",coverURL:"https://cdn.intechopen.com/books/images_new/956.jpg",editedByType:"Edited by",editors:[{id:"91317",title:"Dr.",name:"Dinesh",surname:"Sriramulu",slug:"dinesh-sriramulu",fullName:"Dinesh Sriramulu"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"2303",title:"Gel Electrophoresis",subtitle:"Advanced Techniques",isOpenForSubmission:!1,hash:"99b6af88dfcbe43d82dc7293184207c1",slug:"gel-electrophoresis-advanced-techniques",bookSignature:"Sameh Magdeldin",coverURL:"https://cdn.intechopen.com/books/images_new/2303.jpg",editedByType:"Edited by",editors:[{id:"123648",title:"Dr.",name:"Sameh",surname:"Magdeldin",slug:"sameh-magdeldin",fullName:"Sameh Magdeldin"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3092",title:"Anopheles mosquitoes",subtitle:"New insights into malaria vectors",isOpenForSubmission:!1,hash:"c9e622485316d5e296288bf24d2b0d64",slug:"anopheles-mosquitoes-new-insights-into-malaria-vectors",bookSignature:"Sylvie Manguin",coverURL:"https://cdn.intechopen.com/books/images_new/3092.jpg",editedByType:"Edited by",editors:[{id:"50017",title:"Prof.",name:"Sylvie",surname:"Manguin",slug:"sylvie-manguin",fullName:"Sylvie Manguin"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},onlineFirst:{chapter:{type:"chapter",id:"72667",title:"AMOLED Displays with In-Pixel Photodetector",doi:"10.5772/intechopen.93016",slug:"amoled-displays-with-in-pixel-photodetector",body:'\nActive matrix OLED (AMOLED) displays are today’s mainstream consumer displays available in various form factors, such as smart watches, mobile displays, and large area television. They are highly appealing because of their wide viewing angles, nice color saturation and great potential for curved, flexible and/or rollable format. There are several options for (flexible) backplane technologies based on thin-film transistors (TFTs), namely, metal-oxide TFTs (such as indium gallium zinc oxide or IGZO), low-temperature polycrystalline silicon (LTPS) TFTs, or a combination of IGZO and LTPS, more precisely LTPO or low-temperature polycrystalline silicon and metal oxide. All these technologies have their pros and cons. Among others, IGZO semiconductors are n-type only which is sufficient for a backplane driving an OLED but is less adequate for peripheral circuits. Another key important asset of IGZO is the ultralow source-drain leakage current due to the large bandgap of the semiconductor, enabling long retention times of data storing, i.e., pixels are not leaking. In contrary, LTPS has both n- and p-type devices and thus the capability of CMOS circuits. LTPS transistors can drive larger currents due to the intrinsically higher mobility, enabling complex in-pixel compensation schemes and peripheral circuits. However, with LTPS transistors the leakage will be larger. This is a key reason why LTPO has been developed: this technology combines the ultralow leakage current of IGZO and a p-type LTPS transistor resulting in a hybrid complementary technology. An OLED is an organic LED emitting light directly proportional to its forward current. Therefore it requires a current source as driver in the pixel. In many cases, this is achieved by placing a TFT in series with the OLED and driving it in saturation.
\nIn this chapter, we will investigate the potential to embed additional functionalities in the display. Therefore, several strategies will be discussed focusing on improving the resolution of the current displays, by technology optimization introducing photolithography patterning of the OLED and by design evaluating external compensation vs. internal compensation. The extra space in the pixel, due to the combination of photolithography and simple pixel circuit, provides opportunities to include extra functions at the same original area. The focus in this book chapter is to add a photosensitive detector for fingerprint and palmprint readout.
\nResolution (number of pixels) and pixel pitch (size and spacing of pixels) are two main parameters defining the architecture of the display arrays. The first, expressed typically in megapixels, is standardized by the content type, resulting in different generations of TVs: VGA, full HD, 4K, and, most recently, 8K. The latter, expressed typically in pixels per inch (ppi) or pixels per degree (ppd), is used as a benchmark for smartphones, with high-end models featuring densities in the range of 600 ppi. This is a value that gives a good enough image quality for hand-held devices, with the viewing distance of approximately 30 cm (1 foot). At the same time, future near-to-eye augmented reality/virtual reality (AR/VR) displays impose ultrahigh definition, as the pixel density needs to be beyond the pattern resolving capabilities of the human retina (30 cycles per degree) [1, 2]. The resolution should be maximized to provide the highest possible output within the eye box in any given point of the 180° field of view (FOV), also to enable foveated rendering. An aperture ratio close to unity will eliminate the screen door effect and ensure natural experience. Transparency is necessary to avoid sense of isolation from the real-world view and to diversify from the virtual reality (VR) headsets (Figure 1). To realize all of the above, we need both the microdisplay-like pixel pitch down-scaling [3] and the flat-panel-display-like (FPD) backplane size up-scaling [4, 5]. Switching to advanced nodes in flat panel backplane manufacturing can result in ultrahigh-definition, direct-view AR displays fabricated in a cost-effective way.
\nColor-by-white vs. RGB OLED frontplane can be fabricated on top of CMOS or TFT backplane. Each combination is suitable for different applications.
In order to realize an ultrahigh resolution display, all elements of the system (backplane, frontplane, and driving) need to provide appropriate pixel density. On the frontplane side, several options for the light source can be chosen (Figure 2). OLED technology currently dominates the smartphone display industry not only with performance but also with the cost structure. In this case, the colors are defined by depositing separate device stacks for each color, which is typically referred to as side-by-side, red-green-blue (RGB) array. In OLED TVs, one common white OLED stack is combined with a color filter array (CFA). The limitation of the side-by-side RGB array is the pixel density, limited by the fine metal masking (FMM) technology, which uses deposition through a metal mesh. The white OLED array can achieve very small pixel pitch, which is only limited by the backplane and CFA resolution but imposes brightness loss due to CF transmission. Patterning multicolor OLEDs by photolithography can address the needs of ultralow pixel pitch for the future AR displays by realizing side-by-side OLED stacks with extreme density.
\nVarious display configuration options.
Patterning OLEDs by photolithography is an emerging, disruptive fabrication technique. The main challenge is the extreme chemical sensitivity of OLED materials with solvent, moisture, air, and temperature exposure responsible for performance degradation. The choice of appropriate photolithography chemistry is crucial, with fluorinated [6] or non-fluorinated systems [7] as the dominant options. Figure 3 shows the concept of using a negative-type photoresist to define patterns on top of OLED in a subtractive approach. First, the OLED stack is deposited as a plain layer over the entire substrate, on top of a pixel definition layer (PDL). This defines the active area of the light emitter. Second, photoresist is deposited on top of the entire substrate. Then, it is exposed through a lithography mask and developed to obtain the required pattern. Afterwards, the OLED layers that are not covered by the photoresist are etched away (typically with dry etching, such as reactive ion etch). In the end, the photoresist is stripped to achieve patterned OLED islands.
\nProcess flow for photolithography patterning of OLED stacks.
Photolithography allows pattern transfer beyond 1 μm resolution, enabling high-density lines and spaces. Transfer of small islands means that, with appropriate alignment (e.g., with an i-line stepper), a pixel density of a few thousand pixels per inch (ppi) can be realized. Transfer of openings means that pixel spacing can be minimized, resulting in a high aspect ratio. This is applicable for both TFT-based flat panel displays and CMOS-based microdisplays. Tests on patterning the OLED emission layer have shown that it is possible to achieve 1 μm pitch lines and spaces (Figure 4). Furthermore, the photoluminescence signal of the EML is maintained proving compatibility of this process with OLED material. 1 μm presented here is not a fundamental limit of the approach but rather a limit of the lithography mask design used in the experiment.
\nOLED patterns of 1, 2, 3 and 4 μm: optical and corresponding photoluminescence pictures of red EML patterned as lines (left) and spaces (right).
The achievable pixel density of the frontplane is limited not only by the photoresist used but also by the critical dimension (CD) and alignment/overlay accuracy of the litho tools used. In the i-line steppers typical for flat panel manufacturing, the achievable CD is 1.5 μm with an overlay between 0.25 and 0.5 μm. In contrast, CMOS fabs used for microdisplay manufacturing feature more advanced semiconductor nodes, with 248 nm KrF or 193 nm ArF light sources. Assuming a minimum PDL opening (defining the active area) of 500 nm, a 1.5 μm node imposes a density limit of 3500 ppi (for RGB) with an aperture ratio below 5%. Going to KrF steppers, the achievable density increases to 10,000 ppi while keeping the aperture ratio above 35%. This demonstrates the need of a tooling upgrade for future AR displays, both for the frontplane and the backplane. Denser and more efficient packing of pixels requires scaling down of the technology node, especially in FPD manufacturing.
\nOLED patterning by photolithography means that the deposition of the stack is interrupted (vacuum break) and the photoresist interacts with the organic materials. In the most simple case, the photolithography process is performed in a clean room in ambient atmosphere. The devices are loaded back into the glove box after the etch step for each color and after the photoresist strip when all colors are finished. This raises a serious challenge for the device lifetime. If the process is not optimized for compatibility with the stack, the current-voltage-luminance (IVL) curve shifts to the right (increased turn-on voltage) and to the bottom (reduced luminance). As a consequence, the brightness of the patterned OLED drops very fast and disappears even after a few minutes (Figure 5). Optimization of the photoresist system, of the OLED stack [8] and of the fabrication process, is needed to achieve OLED performance enabling implementation into devices. At imec, we demonstrated phosphorescent green OLED with T90 lifetime of >150 h at the starting brightness of 1000 nit. Efficiency remained above 85 cd/A before and after patterning. Current performance is considered an important step on the path to industrial technology readiness level, estimated to be T97 of at least 1000 h (for the green stack) [8].
\nIVL and lifetime curves for reference OLED and the possible effects of degradation by patterning.
\nFigure 6 shows an example comparison of unpatterned and patterned OLED lifetime curve at initial brightness of 1000 nit. The performance improvement can bring the two curves closer together.
\nLifetime curves of a phosphorescent green OLED at 1000 nit starting brightness for unpatterned and patterned stack.
OLED photolithography was used to fabricate passive displays with a 1400 × 1400 pixel array (almost 2 megapixels). 6 μm metal lines and 10 μm line pitch with SiN pixel definition layer (PDL) were used on glass substrate. Green and red OLED stacks were deposited by thermal evaporation in ultrahigh vacuum. After deposition of the first color (until above emission layer), photoresist was spin-coated, baked, exposed, and developed. Then, the OLED stack not covered by the photoresist was removed by dry etching. After that, the sample went back to the ultrahigh vacuum chamber for second color deposition, and the patterning process was repeated, this time finishing with stripping the photoresist. A semitransparent top contact stack was subsequently deposited, and the display was encapsulated with cavity glass. Both colors can be driven separately, and the PDL design allows for emission of a fixed image specified for each color (Figure 7). Subpixel pitch of 10 μm resulted in smooth edges and excellent feature representation. The device was tested for tens of hours with both colors on. No drop of brightness nor appearance of defects could be observed [9].
\nPassive 1250 ppi patterned OLED display with 1400 × 1400 pixels, 10 μm subpixel pitch, and independent color driving: general view (left) and detailed view for different color drivings (right).
This fabrication process is compatible with both CMOS backplanes and flexible TFT backplanes. The frontplane can thus be implemented in an active matrix display. Of course, photolithography can be used several times to realize more colors for a full-color display.
\nTo increase the display resolution, not only the technology (backplane and frontplane) but also the pixel driving techniques should be optimized. The OLED light output is dependent on the drain current of the driving TFTs of the AMOLED displays. Due to inherent variations in AMOLED displays, some compensation methods to the drain current of the TFTs are required to achieve uniform brightness. This can be implemented through either in-pixel compensation [10] or external compensation [11, 12]. Since in-pixel compensation schemes typically require more transistors inside the pixel, external compensation methods are preferred for high-resolution applications. Figure 8 shows pixel circuits and a possible layout for in-pixel compensation, using an 8T1C [10] pixel, and external compensation using a 3T2C [11] and, respectively, a 2T1C [12] pixel. For all these layouts, the same design rules were used. It is clear from this figure that a display with external compensation, especially the 2T1C pixel circuit, can achieve a much higher pixel density.
\nPixel circuits and corresponding layouts for (left) 8T1C, (middle) 3T2C, and (right) 2T1C pixels.
The achievable pixel density depends on both the pixel circuit and the design rules imposed by the technology, such as the critical dimension (CD) of the lithography tool. Figure 9 compares the achievable resolutions for different CDs for the 8T1C, the 3T2C, and the 2T1C pixel circuit. Although the CD of 1.5 μm, as currently achievable with typical i-line steppers, only yields a maximum pixel density of 565 ppi for the 8T1C pixel circuit, the same CD already yields a significant improvement for the pixel circuits using external compensation, namely, 847 ppi for the 3T2C pixel circuit and 1210 ppi for the 2T1C pixel circuit, respectively. Furthermore, improvements in technology allowing smaller CD will even further increase the achievable pixel density, up to 9070 ppi for the 2T1C pixel circuit, when using a CD of 0.2 μm.
\nPixel resolution vs. critical dimension (CD) for various pixel schemes.
The compensation principle for the 3T2C pixel circuit relies on the fact that applying a voltage on the backgate of a transistor will shift the threshold voltage (VT) of that transistor. By applying the correct compensation voltage to the backgate of the drive transistor of each pixel, all VT variations can be eliminated, resulting in a more uniform display. This compensation method uses three different modes of operation for the display. The first mode of operation is the calibration mode. In this mode, the correct compensation voltage is determined for each pixel by applying a certain reference voltage to the frontgate and measuring the current through the pixel while varying the backgate. When the measured current matches a predetermined reference current, the voltage on the backgate is the correct compensation voltage, which will be stored both on the capacitor connected to the backgate and in external memory. Once the correct backgate voltage is set for every pixel, the display can be switched to normal operation. In this mode, the display is driven with the normal video data, which is written to the frontgate of each pixel. Since the CAL signal is low in this mode, the charge on the capacitor will remain, and hence the backgate voltage will be the compensated voltage. However, due to leakage, this charge will slowly change over time. Therefore, a third mode of operation is added, namely, the calibration refresh. In this mode, the SEL signal is kept low, but the CAL signal is running through the display, while the compensation data is applied to the data lines. This way the compensation voltage is restored on the backgate, to ensure the VT uniformity remains over time. This compensation method shows a significant improvement in current variation, as demonstrated in Figure 10.
\nCurrent variation of a 3T2C display before and after compensation.
The current through the drive TFT (IDS), and thus through the OLED, when operating in saturation regime can be calculated for a certain data voltage (VGS) by using Eq. (1):
\nCompensating only for VT can eliminate variations in current for one gray level; however, if the β-factor is different for each pixel, the current will still vary for different gray values, even after VT compensation. This is shown in Figure 11 for the 3T2C pixel. As a consequence, we propose a new compensation method to compensate for both β and VT variations. Similarly as the previous described compensation method, we will first characterize the current through each pixel for multiple data voltages, whereafter the measurements are fitted to Eq. (1).
\nCurrent variation of a 3T2C and 2T1C display before and after compensation.
For each pixel, the extracted β and VT values are stored. Based on these values, the VGS voltages can be calculated for each pixel by the driver IC for each desired gray level by using Eq. (2):
\nThis calculation is relative simple and straightforward, as it only requires a multiplication, a subtraction, and a square root calculation, which enables to display real-time video content by using this methodology. Figure 11 shows the current variation improvements directly obtained from our AMOLED displays, by utilizing the VT-only compensation method and comparing it to the VT and β compensation method. As mentioned above, the simple VT compensation method provides good variation results for a small range, whereas the combined parameter method improves the variation across all desired gray levels.
\nFingerprint sensor arrays (Figure 5.1) [13] are becoming a mainstream security mechanism for mobile devices and are today available as autonomous silicon-based component. The integration of the fingerprint sensor array together with AMOLED displays [14, 15, 16] would benefit the footprint of the mobile device and the functionality, enabling detection of multiple fingers at once or even a palmprint.
\nFingerprint sensors combined with AMOLED displays can be realized in three different configurations for the sensor pixels: (1) in the same plane of the display pixels and (2) under and (3) over the display pixels (Figure 12). With sensors in the same plane, the display module gains optical sensing capability by incorporating photodetector pixels between OLED pixels. Sensors, under or above the display, require a separate fingerprint module. A fingerprint module under the display would need a semitransparent display and light scattering management. A fingerprint module over the display requires a transparent imager to avoid changes in display emission. In the previous section, we have demonstrated that a higher resolution backplane can be achieved at the same critical dimension by introducing external compensation methods. This combined with the photolitho-based patterning method of OPD and OLED will the crucial enablers for such a configuration as analyzed in Paragraph 3.
\nFingerprint integration configurations in AMOLED displays.
The pixel circuit architecture of the sensor array can be either passive or active [17]. The passive pixel is depicted in Figure 13 and is comprised by the photoelement, a capacitor, and a select TFT. The main difference of the active pixel is that it requires an extra TFT acting as a local amplifier. For high-resolution applications, the active pixel is not recommended, since its footprint is larger than the footprint of passive pixels.
\nBlock diagram of the proposed in-panel fingerprint sensor array with integrated CSA for each line, multiplexer (MUX), and ADC. Power and driving electronics remain off-panel.
The integration of peripheral readout circuitry in panel side-by-side with the display peripherals is beneficial for resolution, connectivity, and potential lower system cost of the device. In this paragraph TFT-based integrated readout is demonstrated by using our IGZO n-type only TFTs.
\nThe necessary blocks to implement an in-panel readout system are a charge sense amplifier (CSA), a multiplexer (MUX), and an analog to digital converter (ADC). The CSA is reading out the charge stored in each pixel of the array. The MUX is multiplexing the CSA outputs directly to the ADC, decreasing the number of the required ADC converters. The ADC is converting the analog voltage received from the CSA to a digital code. Various TFT-based analog blocks have been demonstrated in the literature [18, 19, 20, 21, 22, 23, 24]. Metal-oxide TFT technologies are preferable due to uniformity over large areas, very low leakage currents, and lower cost over area. In the following section, fast and small footprint ADCs and charge sense amplifiers (CSA) are discussed to meet the specifications of an in-panel fingerprint array.
\nIn Figure 13, the high-level block diagram of the in-panel readout system is shown. The five main blocks are detailed: a two-dimensional (2-D) image sensor array, the CSAs connect on each row of the array, a multiplexer connects four or more rows (MUX), and ADC connects to every MUX and off-panel power and driving electronics. Each column of the 2D image sensor array is readout from the corresponding row by a CSA. The pixels are readout subsequently enabled by the “SELECT” signals from the columns and converted to digital code through the MUX and an ADC. The MUX enables a larger footprint for the ADC, up to 4 to 8 times larger compared to a single line (50 μm). Hence, the ADC and MUX needs to be 4 to 8 times faster than the CSA. A 1–2 fps readout of 1M pixel imager (1000 × 1000 pixels) sets a readout speed of 1–2 kS/s per line for each CSA. This translates to 4–8 kS/s for the ADC if a 4:1 MUX is used or 8–16 kS/s for a 8:1 MUX. The slower ADC configuration sets the specification limitation to the width of the ADC to 200 μm, whereby the faster allows a width of 400 μm.
\n\nFigure 14 (a) depicts the cross section of the dual-gate self-aligned metal-oxide (MO) technology on a 15-μm-thick polyimide film [25, 26]. The metal-oxide (IGZO or ITZO) TFTs are fabricated with two metal gates (M0, M1) and source-drain metal contacts (M2). An additional metal layer (M3), not shown in the cross section, is beneficial for footprint but also for performance and noise. The CSA experimental results shown in the following sections are designed with an extra metal layer, also used as anode layer.
\n(a) Cross section of dual-gate self-aligned metal-oxide technology on flexible polyimide substrate and (b) extracted on-current (ION) from experimental data of 480/20 (μm/μm) dual-gate self-aligned ITZO (red) and IGZO (orange) TFTs.
\nFigure 14(b) shows the distribution of the extracted on-current (ION) from the measured transfer characteristics of 480/20 (μm/μm) IGZO (red) and ITZO (orange) dual-gate TFTs. The IGZO TFTs exhibits a median ION of 54.4 μA, whereas the ITZO dual-gate TFT exhibits a median of 250.4 μA. Although the ION of the ITZO TFT is 5 times larger, the normalized spread of ION to the median over the wafer is double (15.4% for ITZO and 8.8% for IGZO). Threshold voltage is also extracted from the same measurements, yielding 1.16 V (and σVt = 242 mV) for ITZO and 1.77 V (and σVt = 94 mV) for IGZO TFTs. The 480/20 TFT is the largest footprint TFT used in the implemented designs. In Figure 15, microphotos of the (a) ADC and (b) the L = 3 μm CSA are shown.
\nMicrophotos of the (a) ADC and (b) L = 3 μm CSA on flexible substrate.
The schematic of the CSA is shown in the Figure 16(a). The schematic of the operational amplifier (OPAMP) used in the CSA is shown in Figure 16(b). The OPAMP comprises a differential pair and a load that is driven by a two-stage buffer, initiated by a start-up circuit. The driver consists of two diode-connected load inverters as input and output stages. The output stage is driven by a start-up circuit to initialize the operation and provide ~1 loop gain positive feedback bias to the n-type load of the differential amplifier such that gate voltage follows source voltage. A buffer is also included at the output nodes A and B to increase the speed of the amplifier.
\nSchematic of (a) charge sense amplifier (CSA) and (b) the OPAMP schematic using dual-gate self-aligned TFTs used in the CSA in (a).
The experimental results of open-loop experiments of the OPAMP are shown in Figure 17 for dual-gate self-aligned IGZO TFTs of minimum channel length of L = 5 μm. The maximum gain for the 5 μm design is 43.2 dB with a phase margin of 52°. Both parameters are critical for stable closed-loop operation of an OPAMP. The obtained bandwidth (BW) is 1.4 kHz, and gain-bandwidth reaches 205 kHz. These specs are compared to other publications in the state-of-the-art Table 1 using TFTs. The footprint of the CSA is 0.28 mm2 with the capacitors. The footprint of the CSA can be decreased to 0.07 mm2 if 3 μm design is implemented. These footprints will result in a bezel width of 5.5 mm (L = 5 μm) and 1.3 mm (L = 3 μm) [27] for a 50 μm pixel size.
\nExperimental bode plots of the OPAMP using dual-gate self-aligned IGZO technology for L = 5 μm.
Circuit | \nThis work | \n2018 [11] | \n2012 [8] | \n2013 [10] | \n2014 [9] | \n
---|---|---|---|---|---|
Supply (V) | \n15 | \n10.5 | \n5 | \n50 | \n|
Gain (dB) | \n32 | \n~21 | \n18.7 | \n19.2 | \n|
GBW (kHz) | \n140 | \n2 | \n472 | \n100\n*\n\n | \n|
pm (o) | \n53 | \n50\n*\n\n | \nneg | \n46 | \n|
Area (mm2) | \n0.3 | \n\n | \n2.08 | \n— | \n|
Substrate | \nPI | \n\n | PI | \nGlass | \n|
L (μm) | \n5 | \n10 | \n6 | \n10 | \n
In-Ga-Zn-O-TFT differential amplifier comparison.
Estimated.
The successive approximation C-2C architecture is selected as ADC architecture, due to the low power dissipation and the 0.1% uniformity of metal-insulator-metal capacitors across large-area thin-film wafers. The schematic of the ADC is shown in Figure 18. The comparator is the most critical building block of the ADC for speed and accuracy. To improve the accuracy of the comparator, open-loop offset cancelation [28] is used. The response of a L = 5 μm dual-gate self-aligned TFT-based comparator at 10 kHz for two inputs ΔVin = 0 and 10 mV is shown in Figure 19. The offset of the comparator is minimized to less than 10 mV using open-loop cancelation, even though the Vt variation of the TFTs is one order larger.
\nThe implemented SADG TFT ADC block diagram driven with offset compensation.
Measured comparator output with auto-zero offset cancelation for designs using TFTs of minimum L = 5 μm at 10 kHz.
The experimental results of the reconstructed samples from a sinusoidal analog wave applied at the input of the IGZO ADC are shown in Figure 20(a). The IGZO ADC achieves 6-bit resolution at a sampling speed of 133 S/s at 15 V power supply using a L = 20 μm comparator. The clock speed of the IGZO ADC is at 2 kHz matching the bandwidth of the comparator, and 15 clocks are required to complete the conversion. Two options are available to increase the sampling speed of the ADC as set by the specification for 1–2 fps fingerprint readout: channel length downscaling and/or change of TFT technology or change of ADC architecture to flash but then for 6-bit the area might increase dramatically due to the multiple resistors needed and 64 comparators.
\n(a) The applied analog input of 2.061 Hz sinewave signal to the ADC and the reconstructed output points from the digital output of the ADC at a clock frequency of 2 kHz for IGZO and (b) the applied analog input of 15.625 Hz sinewave to the 15 kHz clocked ITZO ADC and the reconstructed output.
The minimum length of the TFTs of the measured ADC is L = 20 μm. The length of the TFT of the comparator of the ADC defines the speed of the circuit. In Figure 19 the response of the L = 5 μm comparator is shown validating 10 kHz operation, 5 times faster compared to the 20 μm comparator used in the ADC. This indicates that 5 μm comparator can increase the sampling speed by 5 times.
\nAnother option to enable a larger increase of the ADC speed is to introduce ITZO TFT for the ADC. ITZO TFT exhibits 5 times larger ION which leads to faster responses [Figure 20(b)]. The ITZO ADC achieves a similar bit resolution of the applied sinusoidal wave at 1 kS/s sampling speed and at 10 V supply voltage. Combining both ITZO and downscaling of the length of the TFTs of the comparator will lead to sampling speeds above 4 kS/s as required for the in-panel readout system of 1 fps. The power dissipation of the ITZO ADC is at 550 μW at 10 V power supply and at 110 μW at 15 V power supply for the IGZO implementation.
\nIn conclusion, TFT-based in-panel analog circuits for 1 fps readout of a fingerprint or palmprints array is presented in this paragraph. The circuit blocks can be integrated side-by-side to the flat panel display with integrated sensor array. Two analog blocks are discussed, being an analog to digital converter and charge sense amplifier. ADCs and CSA downscaling to 5 μm including a 500% ION boost of the ITZO TFTs enable the 4 kS/s operation specifications for the in-panel readout circuits. The use of complementary technologies such as LTPS or LTPO would result an increased performance for important parameters such as the gain-bandwidth and the resolution and speed of the ADC. This will enable a better optimized system for this application.
\nIn this book chapter, we have discussed a roadmap to include additional functionalities on displays by adding a fourth pixel to the display. The purpose of the fourth pixel in this work was a photodetector pixel to realize an in-panel fingerprint or palmprinting function. Several options have been discussed to enable this roadmap. At first, we have elaborated several techniques to realize higher-resolution frontplane (OLED) and TFT backplanes. For the frontplanes, photolitho patterning of the OLED was introduced as a disruptive technology impacting significantly the frontplane resolution. External compensation techniques for the backplane when driving OLEDs are proposed in this book chapter, resulting in a uniform and higher-resolution display by using only 2T1C schemes. As photodetector pixel, we proposed a passive 1 T pixel, with included peripheral circuits to enable a lower system cost.
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',metaTitle:"Odredbe i uvjeti",metaDescription:"Ove Odredbe i uvjeti ističu pravila i regulacije u svezi korištenja IntechOpenove stranice www.intechopen.com i svih poddomena u vlasništvu IntechOpena, tvrtke sa sjedištem u 5 Princes Gate Court, London, SW7 2QJ, Ujedinjeno Kraljevstvo.",metaKeywords:null,canonicalURL:"/page/cro-terms-and-conditions",contentRaw:'[{"type":"htmlEditorComponent","content":"Pristupom na stranicu www.intechopen.com slažete se s ovim odredbama, sa svim primjenjivim zakonskim odredbama, te se slažete s poštovanjem svih lokalnih zakona. Korištenje i/ili pristup ovoj stranici temelji se na potpunom prihvaćanju ovih odredbi. Svi materijali na ovoj stranici zaštićeni su primjenjivim zakonima o autorskim pravima i žigu.
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\n\nSljedeća terminologija odnosi se na Odredbe i uvjete, te na sve naše ugovore:
\n\nKlijent, stranka, vi, vaš odnosi se na vas, osobu koja pristupa ovoj stranici i prihvaća IntechOpenove Odredbe i uvjete;
\n\nKompanija, tvrtka, mi, naše odnosi se na tvrtku IntechOpen;
\n\nStranke, strane odnosi se na klijenta i na nas, ili samo na klijenta ili nas.
\n\nSve odredbe koje se odnose na ponudu, prihvat ili razmatranje plaćanja, a za koja mi pružamo asistenciju klijentu, bilo na ugovoreni ili fiksni način, a s ciljem da se ostvare potrebe i želje klijenta u svezi s našim uslugama, su podložne zakonskim odredbama Ujedinjenog Kraljevstva.
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\n\nMaterijali koji se pojavljuju na IntechOpenovoj stranici mogu sadržavati manje greške, tipfelere ili fotografske greške. IntechOpen može napraviti promjene na bilo kojem materijalu koji se nalazi na stranici u bilo koje vrijeme.
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\n"}]},successStories:{items:[]},authorsAndEditors:{filterParams:{},profiles:[{id:"396",title:"Dr.",name:"Vedran",middleName:null,surname:"Kordic",slug:"vedran-kordic",fullName:"Vedran Kordic",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/396/images/7281_n.png",biography:"After obtaining his Master's degree in Mechanical Engineering he continued his education at the Vienna University of Technology where he obtained his PhD degree in 2004. He worked as a researcher at the Automation and Control Institute, Faculty of Electrical Engineering, Vienna University of Technology until 2008. His studies in robotics lead him not only to a PhD degree but also inspired him to co-found and build the International Journal of Advanced Robotic Systems - world's first Open Access journal in the field of robotics.",institutionString:null,institution:{name:"TU Wien",country:{name:"Austria"}}},{id:"441",title:"Ph.D.",name:"Jaekyu",middleName:null,surname:"Park",slug:"jaekyu-park",fullName:"Jaekyu Park",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/441/images/1881_n.jpg",biography:null,institutionString:null,institution:{name:"LG Corporation (South Korea)",country:{name:"Korea, South"}}},{id:"465",title:"Dr.",name:"Christian",middleName:null,surname:"Martens",slug:"christian-martens",fullName:"Christian Martens",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Rheinmetall (Germany)",country:{name:"Germany"}}},{id:"479",title:"Dr.",name:"Valentina",middleName:null,surname:"Colla",slug:"valentina-colla",fullName:"Valentina Colla",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/479/images/358_n.jpg",biography:null,institutionString:null,institution:{name:"Sant'Anna School of Advanced Studies",country:{name:"Italy"}}},{id:"494",title:"PhD",name:"Loris",middleName:null,surname:"Nanni",slug:"loris-nanni",fullName:"Loris Nanni",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/494/images/system/494.jpg",biography:"Loris Nanni received his Master Degree cum laude on June-2002 from the University of Bologna, and the April 26th 2006 he received his Ph.D. in Computer Engineering at DEIS, University of Bologna. On September, 29th 2006 he has won a post PhD fellowship from the university of Bologna (from October 2006 to October 2008), at the competitive examination he was ranked first in the industrial engineering area. He extensively served as referee for several international journals. He is author/coauthor of more than 100 research papers. He has been involved in some projects supported by MURST and European Community. His research interests include pattern recognition, bioinformatics, and biometric systems (fingerprint classification and recognition, signature verification, face recognition).",institutionString:null,institution:null},{id:"496",title:"Dr.",name:"Carlos",middleName:null,surname:"Leon",slug:"carlos-leon",fullName:"Carlos Leon",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Seville",country:{name:"Spain"}}},{id:"512",title:"Dr.",name:"Dayang",middleName:null,surname:"Jawawi",slug:"dayang-jawawi",fullName:"Dayang Jawawi",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Technology Malaysia",country:{name:"Malaysia"}}},{id:"528",title:"Dr.",name:"Kresimir",middleName:null,surname:"Delac",slug:"kresimir-delac",fullName:"Kresimir Delac",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/528/images/system/528.jpg",biography:"K. Delac received his B.Sc.E.E. degree in 2003 and is currentlypursuing a Ph.D. degree at the University of Zagreb, Faculty of Electrical Engineering andComputing. His current research interests are digital image analysis, pattern recognition andbiometrics.",institutionString:null,institution:{name:"University of Zagreb",country:{name:"Croatia"}}},{id:"557",title:"Dr.",name:"Andon",middleName:"Venelinov",surname:"Topalov",slug:"andon-topalov",fullName:"Andon Topalov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/557/images/1927_n.jpg",biography:"Dr. Andon V. Topalov received the MSc degree in Control Engineering from the Faculty of Information Systems, Technologies, and Automation at Moscow State University of Civil Engineering (MGGU) in 1979. He then received his PhD degree in Control Engineering from the Department of Automation and Remote Control at Moscow State Mining University (MGSU), Moscow, in 1984. From 1985 to 1986, he was a Research Fellow in the Research Institute for Electronic Equipment, ZZU AD, Plovdiv, Bulgaria. In 1986, he joined the Department of Control Systems, Technical University of Sofia at the Plovdiv campus, where he is presently a Full Professor. He has held long-term visiting Professor/Scholar positions at various institutions in South Korea, Turkey, Mexico, Greece, Belgium, UK, and Germany. And he has coauthored one book and authored or coauthored more than 80 research papers in conference proceedings and journals. His current research interests are in the fields of intelligent control and robotics.",institutionString:null,institution:{name:"Technical University of Sofia",country:{name:"Bulgaria"}}},{id:"585",title:"Prof.",name:"Munir",middleName:null,surname:"Merdan",slug:"munir-merdan",fullName:"Munir Merdan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/585/images/system/585.jpg",biography:"Munir Merdan received the M.Sc. degree in mechanical engineering from the Technical University of Sarajevo, Bosnia and Herzegovina, in 2001, and the Ph.D. degree in electrical engineering from the Vienna University of Technology, Vienna, Austria, in 2009.Since 2005, he has been at the Automation and Control Institute, Vienna University of Technology, where he is currently a Senior Researcher. 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He won the “Catedra Telefonica” Awards in Modality of Knowledge Transfer, 2017, 2018, and 2019 editions, and awards in Modality of COVID Research in 2020.\n\nPublic References:\nResearcher ID http://www.researcherid.com/rid/N-5967-2014\nORCID https://orcid.org/0000-0002-4621-2768 \nScopus Author ID https://www.scopus.com/authid/detail.uri?authorId=6602376272\nScholar Google https://scholar.google.es/citations?user=G1ks9nIAAAAJ&hl=en \nResearchGate https://www.researchgate.net/profile/Carlos_Travieso",institutionString:null,institution:{name:"University of Las Palmas de Gran Canaria",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null},{id:"23",title:"Computational Neuroscience",coverUrl:"https://cdn.intechopen.com/series_topics/covers/23.jpg",isOpenForSubmission:!0,editor:{id:"14004",title:"Dr.",name:"Magnus",middleName:null,surname:"Johnsson",slug:"magnus-johnsson",fullName:"Magnus Johnsson",profilePictureURL:"https://mts.intechopen.com/storage/users/14004/images/system/14004.png",biography:"Dr Magnus Johnsson is a cross-disciplinary scientist, lecturer, scientific editor and AI/machine learning consultant from Sweden. \n\nHe is currently at Malmö University in Sweden, but also held positions at Lund University in Sweden and at Moscow Engineering Physics Institute. \nHe holds editorial positions at several international scientific journals and has served as a scientific editor for books and special journal issues. \nHis research interests are wide and include, but are not limited to, autonomous systems, computer modeling, artificial neural networks, artificial intelligence, cognitive neuroscience, cognitive robotics, cognitive architectures, cognitive aids and the philosophy of mind. \n\nDr. Johnsson has experience from working in the industry and he has a keen interest in the application of neural networks and artificial intelligence to fields like industry, finance, and medicine. \n\nWeb page: www.magnusjohnsson.se",institutionString:null,institution:{name:"Malmö University",institutionURL:null,country:{name:"Sweden"}}},editorTwo:null,editorThree:null},{id:"24",title:"Computer Vision",coverUrl:"https://cdn.intechopen.com/series_topics/covers/24.jpg",isOpenForSubmission:!0,editor:{id:"294154",title:"Prof.",name:"George",middleName:null,surname:"Papakostas",slug:"george-papakostas",fullName:"George Papakostas",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002hYaGbQAK/Profile_Picture_1624519712088",biography:"George A. 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He has (co)authored more than 150 publications in indexed journals, international conferences and book chapters, 1 book (in Greek), 3 edited books, and 5 journal special issues. His publications have more than 2100 citations with h-index 27 (GoogleScholar). His research interests include computer/machine vision, machine learning, pattern recognition, computational intelligence. \nDr. Papakostas served as a reviewer in numerous journals, as a program\ncommittee member in international conferences and he is a member of the IAENG, MIR Labs, EUCogIII, INSTICC and the Technical Chamber of Greece (TEE).",institutionString:null,institution:{name:"International Hellenic University",institutionURL:null,country:{name:"Greece"}}},editorTwo:null,editorThree:null},{id:"25",title:"Evolutionary Computation",coverUrl:"https://cdn.intechopen.com/series_topics/covers/25.jpg",isOpenForSubmission:!0,editor:{id:"136112",title:"Dr.",name:"Sebastian",middleName:null,surname:"Ventura Soto",slug:"sebastian-ventura-soto",fullName:"Sebastian Ventura Soto",profilePictureURL:"https://mts.intechopen.com/storage/users/136112/images/system/136112.png",biography:"Sebastian Ventura is a Spanish researcher, a full professor with the Department of Computer Science and Numerical Analysis, University of Córdoba. 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In the last five years, he has published more than 60 papers in international journals indexed in the JCR (around 70% of them belonging to first quartile journals) and he has edited some Springer books “Supervised Descriptive Pattern Mining” (2018), “Multiple Instance Learning - Foundations and Algorithms” (2016), and “Pattern Mining with Evolutionary Algorithms” (2016). He has also been involved in more than 20 research projects supported by the Spanish and Andalusian governments and the European Union. He currently belongs to the editorial board of PeerJ Computer Science, Information Fusion and Engineering Applications of Artificial Intelligence journals, being also associate editor of Applied Computational Intelligence and Soft Computing and IEEE Transactions on Cybernetics. Finally, he is editor-in-chief of Progress in Artificial Intelligence. 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He is currently a principal researcher in data analytics and optimisation at TECNALIA (Spain), a visiting fellow at the Basque Center for Applied Mathematics (BCAM) and a part-time lecturer at the University of the Basque Country (UPV/EHU). His research interests gravitate on the use of descriptive, prescriptive and predictive algorithms for data mining and optimization in a diverse range of application fields such as Energy, Transport, Telecommunications, Health and Industry, among others. In these fields he has published more than 240 articles, co-supervised 8 Ph.D. theses, edited 6 books, coauthored 7 patents and participated/led more than 40 research projects. 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Radiotherapy and Nuclear Medicine Technology has always been my aspiration and my life. As years passed I accumulated a tremendous amount of skills and knowledge in Radiotherapy and Nuclear Medicine, Conventional Radiology, Radiation Protection, Bioinformatics Technology, PACS, Image processing, clinically and lecturing that will enable me to provide a valuable service to the community as a Researcher and Consultant in this field. My method of translating this into day to day in clinical practice is non-exhaustible and my habit of exchanging knowledge and expertise with others in those fields is the code and secret of success.",institutionString:null,institution:{name:"Majmaah University",country:{name:"Saudi Arabia"}}},{id:"313277",title:"Dr.",name:"Bartłomiej",middleName:null,surname:"Płaczek",slug:"bartlomiej-placzek",fullName:"Bartłomiej Płaczek",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/313277/images/system/313277.jpg",biography:"Bartłomiej Płaczek, MSc (2002), Ph.D. (2005), Habilitation (2016), is a professor at the University of Silesia, Institute of Computer Science, Poland, and an expert from the National Centre for Research and Development. His research interests include sensor networks, smart sensors, intelligent systems, and image processing with applications in healthcare and medicine. He is the author or co-author of more than seventy papers in peer-reviewed journals and conferences as well as the co-author of several books. He serves as a reviewer for many scientific journals, international conferences, and research foundations. Since 2010, Dr. Placzek has been a reviewer of grants and projects (including EU projects) in the field of information technologies.",institutionString:"University of Silesia",institution:{name:"University of Silesia",country:{name:"Poland"}}},{id:"35000",title:"Prof.",name:"Ulrich H.P",middleName:"H.P.",surname:"Fischer",slug:"ulrich-h.p-fischer",fullName:"Ulrich H.P Fischer",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/35000/images/3052_n.jpg",biography:"Academic and Professional Background\nUlrich H. P. has Diploma and PhD degrees in Physics from the Free University Berlin, Germany. He has been working on research positions in the Heinrich-Hertz-Institute in Germany. Several international research projects has been performed with European partners from France, Netherlands, Norway and the UK. He is currently Professor of Communications Systems at the Harz University of Applied Sciences, Germany.\n\nPublications and Publishing\nHe has edited one book, a special interest book about ‘Optoelectronic Packaging’ (VDE, Berlin, Germany), and has published over 100 papers and is owner of several international patents for WDM over POF key elements.\n\nKey Research and Consulting Interests\nUlrich’s research activity has always been related to Spectroscopy and Optical Communications Technology. Specific current interests include the validation of complex instruments, and the application of VR technology to the development and testing of measurement systems. He has been reviewer for several publications of the Optical Society of America\\'s including Photonics Technology Letters and Applied Optics.\n\nPersonal Interests\nThese include motor cycling in a very relaxed manner and performing martial arts.",institutionString:null,institution:{name:"Charité",country:{name:"Germany"}}},{id:"341622",title:"Ph.D.",name:"Eduardo",middleName:null,surname:"Rojas Alvarez",slug:"eduardo-rojas-alvarez",fullName:"Eduardo Rojas Alvarez",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/341622/images/15892_n.jpg",biography:null,institutionString:null,institution:{name:"University of Cuenca",country:{name:"Ecuador"}}},{id:"215610",title:"Prof.",name:"Muhammad",middleName:null,surname:"Sarfraz",slug:"muhammad-sarfraz",fullName:"Muhammad Sarfraz",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/215610/images/system/215610.jpeg",biography:"Muhammad Sarfraz is a professor in the Department of Information Science, Kuwait University. His research interests include computer graphics, computer vision, image processing, machine learning, pattern recognition, soft computing, data science, intelligent systems, information technology, and information systems. Prof. Sarfraz has been a keynote/invited speaker on various platforms around the globe. He has advised various students for their MSc and Ph.D. theses. He has published more than 400 publications as books, journal articles, and conference papers. He is a member of various professional societies and a chair and member of the International Advisory Committees and Organizing Committees of various international conferences. Prof. Sarfraz is also an editor-in-chief and editor of various international journals.",institutionString:"Kuwait University",institution:{name:"Kuwait University",country:{name:"Kuwait"}}},{id:"32650",title:"Prof.",name:"Lukas",middleName:"Willem",surname:"Snyman",slug:"lukas-snyman",fullName:"Lukas Snyman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/32650/images/4136_n.jpg",biography:"Lukas Willem Snyman received his basic education at primary and high schools in South Africa, Eastern Cape. He enrolled at today's Nelson Metropolitan University and graduated from this university with a BSc in Physics and Mathematics, B.Sc Honors in Physics, MSc in Semiconductor Physics, and a Ph.D. in Semiconductor Physics in 1987. After his studies, he chose an academic career and devoted his energy to the teaching of physics to first, second, and third-year students. After positions as a lecturer at the University of Port Elizabeth, he accepted a position as Associate Professor at the University of Pretoria, South Africa.\r\n\r\nIn 1992, he motivates the concept of 'television and computer-based education” as means to reach large student numbers with only the best of teaching expertise and publishes an article on the concept in the SA Journal of Higher Education of 1993 (and later in 2003). The University of Pretoria subsequently approved a series of test projects on the concept with outreach to Mamelodi and Eerste Rust in 1993. In 1994, the University established a 'Unit for Telematic Education ' as a support section for multiple faculties at the University of Pretoria. In subsequent years, the concept of 'telematic education” subsequently becomes well established in academic circles in South Africa, grew in popularity, and is adopted by many universities and colleges throughout South Africa as a medium of enhancing education and training, as a method to reaching out to far out communities, and as a means to enhance study from the home environment.\r\n\r\nProfessor Snyman in subsequent years pursued research in semiconductor physics, semiconductor devices, microelectronics, and optoelectronics.\r\n\r\nIn 2000 he joined the TUT as a full professor. Here served for a period as head of the Department of Electronic Engineering. Here he makes contributions to solar energy development, microwave and optoelectronic device development, silicon photonics, as well as contributions to new mobile telecommunication systems and network planning in SA.\r\n\r\nCurrently, he teaches electronics and telecommunications at the TUT to audiences ranging from first-year students to Ph.D. level.\r\n\r\nFor his research in the field of 'Silicon Photonics” since 1990, he has published (as author and co-author) about thirty internationally reviewed articles in scientific journals, contributed to more than forty international conferences, about 25 South African provisional patents (as inventor and co-inventor), 8 PCT international patent applications until now. Of these, two USA patents applications, two European Patents, two Korean patents, and ten SA patents have been granted. A further 4 USA patents, 5 European patents, 3 Korean patents, 3 Chinese patents, and 3 Japanese patents are currently under consideration.\r\n\r\nRecently he has also published an extensive scholarly chapter in an internet open access book on 'Integrating Microphotonic Systems and MOEMS into standard Silicon CMOS Integrated circuitry”.\r\n\r\nFurthermore, Professor Snyman recently steered a new initiative at the TUT by introducing a 'Laboratory for Innovative Electronic Systems ' at the Department of Electrical Engineering. The model of this laboratory or center is to primarily combine outputs as achieved by high-level research with lower-level system development and entrepreneurship in a technical university environment. Students are allocated to projects at different levels with PhDs and Master students allocated to the generation of new knowledge and new technologies, while students at the diploma and Baccalaureus level are allocated to electronic systems development with a direct and a near application for application in industry or the commercial and public sectors in South Africa.\r\n\r\nProfessor Snyman received the WIRSAM Award of 1983 and the WIRSAM Award in 1985 in South Africa for best research papers by a young scientist at two international conferences on electron microscopy in South Africa. He subsequently received the SA Microelectronics Award for the best dissertation emanating from studies executed at a South African university in the field of Physics and Microelectronics in South Africa in 1987. In October of 2011, Professor Snyman received the prestigious Institutional Award for 'Innovator of the Year” for 2010 at the Tshwane University of Technology, South Africa. This award was based on the number of patents recognized and granted by local and international institutions as well as for his contributions concerning innovation at the TUT.",institutionString:null,institution:{name:"University of South Africa",country:{name:"South Africa"}}},{id:"317279",title:"Mr.",name:"Ali",middleName:"Usama",surname:"Syed",slug:"ali-syed",fullName:"Ali Syed",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/317279/images/16024_n.png",biography:"A creative, talented, and innovative young professional who is dedicated, well organized, and capable research fellow with two years of experience in graduate-level research, published in engineering journals and book, with related expertise in Bio-robotics, equally passionate about the aesthetics of the mechanical and electronic system, obtained expertise in the use of MS Office, MATLAB, SolidWorks, LabVIEW, Proteus, Fusion 360, having a grasp on python, C++ and assembly language, possess proven ability in acquiring research grants, previous appointments with social and educational societies with experience in administration, current affiliations with IEEE and Web of Science, a confident presenter at conferences and teacher in classrooms, able to explain complex information to audiences of all levels.",institutionString:null,institution:{name:"Air University",country:{name:"Pakistan"}}},{id:"75526",title:"Ph.D.",name:"Zihni Onur",middleName:null,surname:"Uygun",slug:"zihni-onur-uygun",fullName:"Zihni Onur Uygun",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/75526/images/12_n.jpg",biography:"My undergraduate education and my Master of Science educations at Ege University and at Çanakkale Onsekiz Mart University have given me a firm foundation in Biochemistry, Analytical Chemistry, Biosensors, Bioelectronics, Physical Chemistry and Medicine. After obtaining my degree as a MSc in analytical chemistry, I started working as a research assistant in Ege University Medical Faculty in 2014. In parallel, I enrolled to the MSc program at the Department of Medical Biochemistry at Ege University to gain deeper knowledge on medical and biochemical sciences as well as clinical chemistry in 2014. In my PhD I deeply researched on biosensors and bioelectronics and finished in 2020. Now I have eleven SCI-Expanded Index published papers, 6 international book chapters, referee assignments for different SCIE journals, one international patent pending, several international awards, projects and bursaries. In parallel to my research assistant position at Ege University Medical Faculty, Department of Medical Biochemistry, in April 2016, I also founded a Start-Up Company (Denosens Biotechnology LTD) by the support of The Scientific and Technological Research Council of Turkey. Currently, I am also working as a CEO in Denosens Biotechnology. The main purposes of the company, which carries out R&D as a research center, are to develop new generation biosensors and sensors for both point-of-care diagnostics; such as glucose, lactate, cholesterol and cancer biomarker detections. My specific experimental and instrumental skills are Biochemistry, Biosensor, Analytical Chemistry, Electrochemistry, Mobile phone based point-of-care diagnostic device, POCTs and Patient interface designs, HPLC, Tandem Mass Spectrometry, Spectrophotometry, ELISA.",institutionString:null,institution:{name:"Ege University",country:{name:"Turkey"}}},{id:"267434",title:"Dr.",name:"Rohit",middleName:null,surname:"Raja",slug:"rohit-raja",fullName:"Rohit Raja",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/267434/images/system/267434.jpg",biography:"Dr. Rohit Raja received Ph.D. in Computer Science and Engineering from Dr. CVRAMAN University in 2016. His main research interest includes Face recognition and Identification, Digital Image Processing, Signal Processing, and Networking. Presently he is working as Associate Professor in IT Department, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur (CG), India. He has authored several Journal and Conference Papers. He has good Academics & Research experience in various areas of CSE and IT. He has filed and successfully published 27 Patents. He has received many time invitations to be a Guest at IEEE Conferences. He has published 100 research papers in various International/National Journals (including IEEE, Springer, etc.) and Proceedings of the reputed International/ National Conferences (including Springer and IEEE). He has been nominated to the board of editors/reviewers of many peer-reviewed and refereed Journals (including IEEE, Springer).",institutionString:"Guru Ghasidas Vishwavidyalaya",institution:{name:"Guru Ghasidas Vishwavidyalaya",country:{name:"India"}}},{id:"246502",title:"Dr.",name:"Jaya T.",middleName:"T",surname:"Varkey",slug:"jaya-t.-varkey",fullName:"Jaya T. Varkey",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/246502/images/11160_n.jpg",biography:"Jaya T. Varkey, PhD, graduated with a degree in Chemistry from Cochin University of Science and Technology, Kerala, India. She obtained a PhD in Chemistry from the School of Chemical Sciences, Mahatma Gandhi University, Kerala, India, and completed a post-doctoral fellowship at the University of Minnesota, USA. She is a research guide at Mahatma Gandhi University and Associate Professor in Chemistry, St. Teresa’s College, Kochi, Kerala, India.\nDr. Varkey received a National Young Scientist award from the Indian Science Congress (1995), a UGC Research award (2016–2018), an Indian National Science Academy (INSA) Visiting Scientist award (2018–2019), and a Best Innovative Faculty award from the All India Association for Christian Higher Education (AIACHE) (2019). She Hashas received the Sr. Mary Cecil prize for best research paper three times. She was also awarded a start-up to develop a tea bag water filter. \nDr. Varkey has published two international books and twenty-seven international journal publications. She is an editorial board member for five international journals.",institutionString:"St. Teresa’s College",institution:null},{id:"250668",title:"Dr.",name:"Ali",middleName:null,surname:"Nabipour Chakoli",slug:"ali-nabipour-chakoli",fullName:"Ali Nabipour Chakoli",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/250668/images/system/250668.jpg",biography:"Academic Qualification:\r\n•\tPhD in Materials Physics and Chemistry, From: Sep. 2006, to: Sep. 2010, School of Materials Science and Engineering, Harbin Institute of Technology, Thesis: Structure and Shape Memory Effect of Functionalized MWCNTs/poly (L-lactide-co-ε-caprolactone) Nanocomposites. Supervisor: Prof. Wei Cai,\r\n•\tM.Sc in Applied Physics, From: 1996, to: 1998, Faculty of Physics & Nuclear Science, Amirkabir Uni. of Technology, Tehran, Iran, Thesis: Determination of Boron in Micro alloy Steels with solid state nuclear track detectors by neutron induced auto radiography, Supervisors: Dr. M. Hosseini Ashrafi and Dr. A. Hosseini.\r\n•\tB.Sc. in Applied Physics, From: 1991, to: 1996, Faculty of Physics & Nuclear Science, Amirkabir Uni. of Technology, Tehran, Iran, Thesis: Design of shielding for Am-Be neutron sources for In Vivo neutron activation analysis, Supervisor: Dr. M. Hosseini Ashrafi.\r\n\r\nResearch Experiences:\r\n1.\tNanomaterials, Carbon Nanotubes, Graphene: Synthesis, Functionalization and Characterization,\r\n2.\tMWCNTs/Polymer Composites: Fabrication and Characterization, \r\n3.\tShape Memory Polymers, Biodegradable Polymers, ORC, Collagen,\r\n4.\tMaterials Analysis and Characterizations: TEM, SEM, XPS, FT-IR, Raman, DSC, DMA, TGA, XRD, GPC, Fluoroscopy, \r\n5.\tInteraction of Radiation with Mater, Nuclear Safety and Security, NDT(RT),\r\n6.\tRadiation Detectors, Calibration (SSDL),\r\n7.\tCompleted IAEA e-learning Courses:\r\nNuclear Security (15 Modules),\r\nNuclear Safety:\r\nTSA 2: Regulatory Protection in Occupational Exposure,\r\nTips & Tricks: Radiation Protection in Radiography,\r\nSafety and Quality in Radiotherapy,\r\nCourse on Sealed Radioactive Sources,\r\nCourse on Fundamentals of Environmental Remediation,\r\nCourse on Planning for Environmental Remediation,\r\nKnowledge Management Orientation Course,\r\nFood Irradiation - Technology, Applications and Good Practices,\r\nEmployment:\r\nFrom 2010 to now: Academic staff, Nuclear Science and Technology Research Institute, Kargar Shomali, Tehran, Iran, P.O. Box: 14395-836.\r\nFrom 1997 to 2006: Expert of Materials Analysis and Characterization. Research Center of Agriculture and Medicine. Rajaeeshahr, Karaj, Iran, P. O. Box: 31585-498.",institutionString:"Atomic Energy Organization of Iran",institution:{name:"Atomic Energy Organization of Iran",country:{name:"Iran"}}},{id:"248279",title:"Dr.",name:"Monika",middleName:"Elzbieta",surname:"Machoy",slug:"monika-machoy",fullName:"Monika Machoy",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/248279/images/system/248279.jpeg",biography:"Monika Elżbieta Machoy, MD, graduated with distinction from the Faculty of Medicine and Dentistry at the Pomeranian Medical University in 2009, defended her PhD thesis with summa cum laude in 2016 and is currently employed as a researcher at the Department of Orthodontics of the Pomeranian Medical University. She expanded her professional knowledge during a one-year scholarship program at the Ernst Moritz Arndt University in Greifswald, Germany and during a three-year internship at the Technical University in Dresden, Germany. She has been a speaker at numerous orthodontic conferences, among others, American Association of Orthodontics, European Orthodontic Symposium and numerous conferences of the Polish Orthodontic Society. She conducts research focusing on the effect of orthodontic treatment on dental and periodontal tissues and the causes of pain in orthodontic patients.",institutionString:"Pomeranian Medical University",institution:{name:"Pomeranian Medical University",country:{name:"Poland"}}},{id:"252743",title:"Prof.",name:"Aswini",middleName:"Kumar",surname:"Kar",slug:"aswini-kar",fullName:"Aswini Kar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/252743/images/10381_n.jpg",biography:"uploaded in cv",institutionString:null,institution:{name:"KIIT University",country:{name:"India"}}},{id:"204256",title:"Dr.",name:"Anil",middleName:"Kumar",surname:"Kumar Sahu",slug:"anil-kumar-sahu",fullName:"Anil Kumar Sahu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/204256/images/14201_n.jpg",biography:"I have nearly 11 years of research and teaching experience. I have done my master degree from University Institute of Pharmacy, Pt. Ravi Shankar Shukla University, Raipur, Chhattisgarh India. I have published 16 review and research articles in international and national journals and published 4 chapters in IntechOpen, the world’s leading publisher of Open access books. I have presented many papers at national and international conferences. I have received research award from Indian Drug Manufacturers Association in year 2015. My research interest extends from novel lymphatic drug delivery systems, oral delivery system for herbal bioactive to formulation optimization.",institutionString:null,institution:{name:"Chhattisgarh Swami Vivekanand Technical University",country:{name:"India"}}},{id:"253468",title:"Dr.",name:"Mariusz",middleName:null,surname:"Marzec",slug:"mariusz-marzec",fullName:"Mariusz Marzec",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/253468/images/system/253468.png",biography:"An assistant professor at Department of Biomedical Computer Systems, at Institute of Computer Science, Silesian University in Katowice. Scientific interests: computer analysis and processing of images, biomedical images, databases and programming languages. He is an author and co-author of scientific publications covering analysis and processing of biomedical images and development of database systems.",institutionString:"University of Silesia",institution:{name:"University of Silesia",country:{name:"Poland"}}},{id:"212432",title:"Prof.",name:"Hadi",middleName:null,surname:"Mohammadi",slug:"hadi-mohammadi",fullName:"Hadi Mohammadi",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/212432/images/system/212432.jpeg",biography:"Dr. Hadi Mohammadi is a biomedical engineer with hands-on experience in the design and development of many engineering structures and medical devices through various projects that he has been involved in over the past twenty years. Dr. Mohammadi received his BSc. and MSc. degrees in Mechanical Engineering from Sharif University of Technology, Tehran, Iran, and his PhD. degree in Biomedical Engineering (biomaterials) from the University of Western Ontario. He was a postdoctoral trainee for almost four years at University of Calgary and Harvard Medical School. He is an industry innovator having created the technology to produce lifelike synthetic platforms that can be used for the simulation of almost all cardiovascular reconstructive surgeries. He’s been heavily involved in the design and development of cardiovascular devices and technology for the past 10 years. He is currently an Assistant Professor with the University of British Colombia, Canada.",institutionString:"University of British Columbia",institution:{name:"University of British Columbia",country:{name:"Canada"}}},{id:"254463",title:"Prof.",name:"Haisheng",middleName:null,surname:"Yang",slug:"haisheng-yang",fullName:"Haisheng Yang",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/254463/images/system/254463.jpeg",biography:"Haisheng Yang, Ph.D., Professor and Director of the Department of Biomedical Engineering, College of Life Science and Bioengineering, Beijing University of Technology. He received his Ph.D. degree in Mechanics/Biomechanics from Harbin Institute of Technology (jointly with University of California, Berkeley). Afterwards, he worked as a Postdoctoral Research Associate in the Purdue Musculoskeletal Biology and Mechanics Lab at the Department of Basic Medical Sciences, Purdue University, USA. He also conducted research in the Research Centre of Shriners Hospitals for Children-Canada at McGill University, Canada. Dr. Yang has over 10 years research experience in orthopaedic biomechanics and mechanobiology of bone adaptation and regeneration. He earned an award from Beijing Overseas Talents Aggregation program in 2017 and serves as Beijing Distinguished Professor.",institutionString:null,institution:{name:"Beijing University of Technology",country:{name:"China"}}},{id:"89721",title:"Dr.",name:"Mehmet",middleName:"Cuneyt",surname:"Ozmen",slug:"mehmet-ozmen",fullName:"Mehmet Ozmen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/89721/images/7289_n.jpg",biography:null,institutionString:null,institution:{name:"Gazi University",country:{name:"Turkey"}}},{id:"265335",title:"Mr.",name:"Stefan",middleName:"Radnev",surname:"Stefanov",slug:"stefan-stefanov",fullName:"Stefan Stefanov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/265335/images/7562_n.jpg",biography:null,institutionString:null,institution:{name:"Medical University Plovdiv",country:{name:"Bulgaria"}}},{id:"242893",title:"Ph.D. Student",name:"Joaquim",middleName:null,surname:"De Moura",slug:"joaquim-de-moura",fullName:"Joaquim De Moura",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/242893/images/7133_n.jpg",biography:"Joaquim de Moura received his degree in Computer Engineering in 2014 from the University of A Coruña (Spain). In 2016, he received his M.Sc degree in Computer Engineering from the same university. He is currently pursuing his Ph.D degree in Computer Science in a collaborative project between ophthalmology centers in Galicia and the University of A Coruña. His research interests include computer vision, machine learning algorithms and analysis and medical imaging processing of various kinds.",institutionString:null,institution:{name:"University of A Coruña",country:{name:"Spain"}}},{id:"294334",title:"B.Sc.",name:"Marc",middleName:null,surname:"Bruggeman",slug:"marc-bruggeman",fullName:"Marc Bruggeman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/294334/images/8242_n.jpg",biography:"Chemical engineer graduate, with a passion for material science and specific interest in polymers - their near infinite applications intrigue me. \n\nI plan to continue my scientific career in the field of polymeric biomaterials as I am fascinated by intelligent, bioactive and biomimetic materials for use in both consumer and medical applications.",institutionString:null,institution:null},{id:"255757",title:"Dr.",name:"Igor",middleName:"Victorovich",surname:"Lakhno",slug:"igor-lakhno",fullName:"Igor Lakhno",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/255757/images/system/255757.jpg",biography:"Igor Victorovich Lakhno was born in 1971 in Kharkiv (Ukraine). \nMD – 1994, Kharkiv National Medical Univesity.\nOb&Gyn; – 1997, master courses in Kharkiv Medical Academy of Postgraduate Education.\nPh.D. – 1999, Kharkiv National Medical Univesity.\nDSC – 2019, PL Shupik National Academy of Postgraduate Education \nProfessor – 2021, Department of Obstetrics and Gynecology of VN Karazin Kharkiv National University\nHead of Department – 2021, Department of Perinatology, Obstetrics and gynecology of Kharkiv Medical Academy of Postgraduate Education\nIgor Lakhno has been graduated from international training courses on reproductive medicine and family planning held at Debrecen University (Hungary) in 1997. Since 1998 Lakhno Igor has worked as an associate professor in the department of obstetrics and gynecology of VN Karazin National University and an associate professor of the perinatology, obstetrics, and gynecology department of Kharkiv Medical Academy of Postgraduate Education. Since June 2019 he’s been a professor in the department of obstetrics and gynecology of VN Karazin National University and a professor of the perinatology, obstetrics, and gynecology department. He’s affiliated with Kharkiv Medical Academy of Postgraduate Education as a Head of Department from November 2021. Igor Lakhno has participated in several international projects on fetal non-invasive electrocardiography (with Dr. J. A. Behar (Technion), Prof. D. Hoyer (Jena University), and José Alejandro Díaz Méndez (National Institute of Astrophysics, Optics, and Electronics, Mexico). He’s an author of about 200 printed works and there are 31 of them in Scopus or Web of Science databases. Igor Lakhno is a member of the Editorial Board of Reproductive Health of Woman, Emergency Medicine, and Technology Transfer Innovative Solutions in Medicine (Estonia). He is a medical Editor of “Z turbotoyu pro zhinku”. Igor Lakhno is a reviewer of the Journal of Obstetrics and Gynaecology (Taylor and Francis), British Journal of Obstetrics and Gynecology (Wiley), Informatics in Medicine Unlocked (Elsevier), The Journal of Obstetrics and Gynecology Research (Wiley), Endocrine, Metabolic & Immune Disorders-Drug Targets (Bentham Open), The Open Biomedical Engineering Journal (Bentham Open), etc. He’s defended a dissertation for a DSc degree “Pre-eclampsia: prediction, prevention, and treatment”. Three years ago Igor Lakhno has participated in a training course on innovative technologies in medical education at Lublin Medical University (Poland). Lakhno Igor has participated as a speaker in several international conferences and congresses (International Conference on Biological Oscillations April 10th-14th 2016, Lancaster, UK, The 9th conference of the European Study Group on Cardiovascular Oscillations). His main scientific interests: are obstetrics, women’s health, fetal medicine, and cardiovascular medicine. \nIgor Lakhno is a consultant at Kharkiv municipal perinatal center. He’s graduated from training courses on endoscopy in gynecology. He has 28 years of practical experience in the field.",institutionString:null,institution:null},{id:"244950",title:"Dr.",name:"Salvatore",middleName:null,surname:"Di Lauro",slug:"salvatore-di-lauro",fullName:"Salvatore Di Lauro",position:null,profilePictureURL:"https://intech-files.s3.amazonaws.com/0030O00002bSF1HQAW/ProfilePicture%202021-12-20%2014%3A54%3A14.482",biography:"Name:\n\tSALVATORE DI LAURO\nAddress:\n\tHospital Clínico Universitario Valladolid\nAvda Ramón y Cajal 3\n47005, Valladolid\nSpain\nPhone number: \nFax\nE-mail:\n\t+34 983420000 ext 292\n+34 983420084\nsadilauro@live.it\nDate and place of Birth:\nID Number\nMedical Licence \nLanguages\t09-05-1985. Villaricca (Italy)\n\nY1281863H\n474707061\nItalian (native language)\nSpanish (read, written, spoken)\nEnglish (read, written, spoken)\nPortuguese (read, spoken)\nFrench (read)\n\t\t\nCurrent position (title and company)\tDate (Year)\nVitreo-Retinal consultant in ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl. National Health System.\nVitreo-Retinal consultant in ophthalmology. Instituto Oftalmologico Recoletas. Red Hospitalaria Recoletas. Private practise.\t2017-today\n\n2019-today\n\t\n\t\nEducation (High school, university and postgraduate training > 3 months)\tDate (Year)\nDegree in Medicine and Surgery. University of Neaples 'Federico II”\nResident in Opthalmology. Hospital Clinico Universitario Valladolid\nMaster in Vitreo-Retina. IOBA. University of Valladolid\nFellow of the European Board of Ophthalmology. Paris\nMaster in Research in Ophthalmology. University of Valladolid\t2003-2009\n2012-2016\n2016-2017\n2016\n2012-2013\n\t\nEmployments (company and positions)\tDate (Year)\nResident in Ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl.\nFellow in Vitreo-Retina. IOBA. University of Valladolid\nVitreo-Retinal consultant in ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl. National Health System.\nVitreo-Retinal consultant in ophthalmology. Instituto Oftalmologico Recoletas. Red Hospitalaria Recoletas. \n\t2012-2016\n2016-2017\n2017-today\n\n2019-Today\n\n\n\t\nClinical Research Experience (tasks and role)\tDate (Year)\nAssociated investigator\n\n' FIS PI20/00740: DESARROLLO DE UNA CALCULADORA DE RIESGO DE\nAPARICION DE RETINOPATIA DIABETICA BASADA EN TECNICAS DE IMAGEN MULTIMODAL EN PACIENTES DIABETICOS TIPO 1. Grant by: Ministerio de Ciencia e Innovacion \n\n' (BIO/VA23/14) Estudio clínico multicéntrico y prospectivo para validar dos\nbiomarcadores ubicados en los genes p53 y MDM2 en la predicción de los resultados funcionales de la cirugía del desprendimiento de retina regmatógeno. Grant by: Gerencia Regional de Salud de la Junta de Castilla y León.\n' Estudio multicéntrico, aleatorizado, con enmascaramiento doble, en 2 grupos\nparalelos y de 52 semanas de duración para comparar la eficacia, seguridad e inmunogenicidad de SOK583A1 respecto a Eylea® en pacientes con degeneración macular neovascular asociada a la edad' (CSOK583A12301; N.EUDRA: 2019-004838-41; FASE III). Grant by Hexal AG\n\n' Estudio de fase III, aleatorizado, doble ciego, con grupos paralelos, multicéntrico para comparar la eficacia y la seguridad de QL1205 frente a Lucentis® en pacientes con degeneración macular neovascular asociada a la edad. (EUDRACT: 2018-004486-13). Grant by Qilu Pharmaceutical Co\n\n' Estudio NEUTON: Ensayo clinico en fase IV para evaluar la eficacia de aflibercept en pacientes Naive con Edema MacUlar secundario a Oclusion de Vena CenTral de la Retina (OVCR) en regimen de tratamientO iNdividualizado Treat and Extend (TAE)”, (2014-000975-21). Grant by Fundacion Retinaplus\n\n' Evaluación de la seguridad y bioactividad de anillos de tensión capsular en conejo. Proyecto Procusens. Grant by AJL, S.A.\n\n'Estudio epidemiológico, prospectivo, multicéntrico y abierto\\npara valorar la frecuencia de la conjuntivitis adenovírica diagnosticada mediante el test AdenoPlus®\\nTest en pacientes enfermos de conjuntivitis aguda”\\n. National, multicenter study. Grant by: NICOX.\n\nEuropean multicentric trial: 'Evaluation of clinical outcomes following the use of Systane Hydration in patients with dry eye”. Study Phase 4. Grant by: Alcon Labs'\n\nVLPs Injection and Activation in a Rabbit Model of Uveal Melanoma. Grant by Aura Bioscience\n\nUpdating and characterization of a rabbit model of uveal melanoma. Grant by Aura Bioscience\n\nEnsayo clínico en fase IV para evaluar las variantes genéticas de la vía del VEGF como biomarcadores de eficacia del tratamiento con aflibercept en pacientes con degeneración macular asociada a la edad (DMAE) neovascular. Estudio BIOIMAGE. IMO-AFLI-2013-01\n\nEstudio In-Eye:Ensayo clínico en fase IV, abierto, aleatorizado, de 2 brazos,\nmulticçentrico y de 12 meses de duración, para evaluar la eficacia y seguridad de un régimen de PRN flexible individualizado de 'esperar y extender' versus un régimen PRN según criterios de estabilización mediante evaluaciones mensuales de inyecciones intravítreas de ranibizumab 0,5 mg en pacientes naive con neovascularización coriodea secunaria a la degeneración macular relacionada con la edad. CP: CRFB002AES03T\n\nTREND: Estudio Fase IIIb multicéntrico, randomizado, de 12 meses de\nseguimiento con evaluador de la agudeza visual enmascarado, para evaluar la eficacia y la seguridad de ranibizumab 0.5mg en un régimen de tratar y extender comparado con un régimen mensual, en pacientes con degeneración macular neovascular asociada a la edad. CP: CRFB002A2411 Código Eudra CT:\n2013-002626-23\n\n\n\nPublications\t\n\n2021\n\n\n\n\n2015\n\n\n\n\n2021\n\n\n\n\n\n2021\n\n\n\n\n2015\n\n\n\n\n2015\n\n\n2014\n\n\n\n\n2015-16\n\n\n\n2015\n\n\n2014\n\n\n2014\n\n\n\n\n2014\n\n\n\n\n\n\n\n2014\n\nJose Carlos Pastor; Jimena Rojas; Salvador Pastor-Idoate; Salvatore Di Lauro; Lucia Gonzalez-Buendia; Santiago Delgado-Tirado. Proliferative vitreoretinopathy: A new concept of disease pathogenesis and practical\nconsequences. Progress in Retinal and Eye Research. 51, pp. 125 - 155. 03/2016. DOI: 10.1016/j.preteyeres.2015.07.005\n\n\nLabrador-Velandia S; Alonso-Alonso ML; Di Lauro S; García-Gutierrez MT; Srivastava GK; Pastor JC; Fernandez-Bueno I. Mesenchymal stem cells provide paracrine neuroprotective resources that delay degeneration of co-cultured organotypic neuroretinal cultures.Experimental Eye Research. 185, 17/05/2019. DOI: 10.1016/j.exer.2019.05.011\n\nSalvatore Di Lauro; Maria Teresa Garcia Gutierrez; Ivan Fernandez Bueno. Quantification of pigment epithelium-derived factor (PEDF) in an ex vivo coculture of retinal pigment epithelium cells and neuroretina.\nJournal of Allbiosolution. 2019. ISSN 2605-3535\n\nSonia Labrador Velandia; Salvatore Di Lauro; Alonso-Alonso ML; Tabera Bartolomé S; Srivastava GK; Pastor JC; Fernandez-Bueno I. Biocompatibility of intravitreal injection of human mesenchymal stem cells in immunocompetent rabbits. Graefe's archive for clinical and experimental ophthalmology. 256 - 1, pp. 125 - 134. 01/2018. DOI: 10.1007/s00417-017-3842-3\n\n\nSalvatore Di Lauro, David Rodriguez-Crespo, Manuel J Gayoso, Maria T Garcia-Gutierrez, J Carlos Pastor, Girish K Srivastava, Ivan Fernandez-Bueno. A novel coculture model of porcine central neuroretina explants and retinal pigment epithelium cells. Molecular Vision. 2016 - 22, pp. 243 - 253. 01/2016.\n\nSalvatore Di Lauro. Classifications for Proliferative Vitreoretinopathy ({PVR}): An Analysis of Their Use in Publications over the Last 15 Years. Journal of Ophthalmology. 2016, pp. 1 - 6. 01/2016. DOI: 10.1155/2016/7807596\n\nSalvatore Di Lauro; Rosa Maria Coco; Rosa Maria Sanabria; Enrique Rodriguez de la Rua; Jose Carlos Pastor. Loss of Visual Acuity after Successful Surgery for Macula-On Rhegmatogenous Retinal Detachment in a Prospective Multicentre Study. Journal of Ophthalmology. 2015:821864, 2015. DOI: 10.1155/2015/821864\n\nIvan Fernandez-Bueno; Salvatore Di Lauro; Ivan Alvarez; Jose Carlos Lopez; Maria Teresa Garcia-Gutierrez; Itziar Fernandez; Eva Larra; Jose Carlos Pastor. Safety and Biocompatibility of a New High-Density Polyethylene-Based\nSpherical Integrated Porous Orbital Implant: An Experimental Study in Rabbits. Journal of Ophthalmology. 2015:904096, 2015. DOI: 10.1155/2015/904096\n\nPastor JC; Pastor-Idoate S; Rodríguez-Hernandez I; Rojas J; Fernandez I; Gonzalez-Buendia L; Di Lauro S; Gonzalez-Sarmiento R. Genetics of PVR and RD. Ophthalmologica. 232 - Suppl 1, pp. 28 - 29. 2014\n\nRodriguez-Crespo D; Di Lauro S; Singh AK; Garcia-Gutierrez MT; Garrosa M; Pastor JC; Fernandez-Bueno I; Srivastava GK. Triple-layered mixed co-culture model of RPE cells with neuroretina for evaluating the neuroprotective effects of adipose-MSCs. Cell Tissue Res. 358 - 3, pp. 705 - 716. 2014.\nDOI: 10.1007/s00441-014-1987-5\n\nCarlo De Werra; Salvatore Condurro; Salvatore Tramontano; Mario Perone; Ivana Donzelli; Salvatore Di Lauro; Massimo Di Giuseppe; Rosa Di Micco; Annalisa Pascariello; Antonio Pastore; Giorgio Diamantis; Giuseppe Galloro. Hydatid disease of the liver: thirty years of surgical experience.Chirurgia italiana. 59 - 5, pp. 611 - 636.\n(Italia): 2007. ISSN 0009-4773\n\nChapters in books\n\t\n' Salvador Pastor Idoate; Salvatore Di Lauro; Jose Carlos Pastor Jimeno. PVR: Pathogenesis, Histopathology and Classification. Proliferative Vitreoretinopathy with Small Gauge Vitrectomy. Springer, 2018. ISBN 978-3-319-78445-8\nDOI: 10.1007/978-3-319-78446-5_2. \n\n' Salvatore Di Lauro; Maria Isabel Lopez Galvez. Quistes vítreos en una mujer joven. Problemas diagnósticos en patología retinocoroidea. Sociedad Española de Retina-Vitreo. 2018.\n\n' Salvatore Di Lauro; Salvador Pastor Idoate; Jose Carlos Pastor Jimeno. iOCT in PVR management. OCT Applications in Opthalmology. pp. 1 - 8. INTECH, 2018. DOI: 10.5772/intechopen.78774.\n\n' Rosa Coco Martin; Salvatore Di Lauro; Salvador Pastor Idoate; Jose Carlos Pastor. amponadores, manipuladores y tinciones en la cirugía del traumatismo ocular.Trauma Ocular. Ponencia de la SEO 2018..\n\n' LOPEZ GALVEZ; DI LAURO; CRESPO. OCT angiografia y complicaciones retinianas de la diabetes. PONENCIA SEO 2021, CAPITULO 20. (España): 2021.\n\n' Múltiples desprendimientos neurosensoriales bilaterales en paciente joven. Enfermedades Degenerativas De Retina Y Coroides. SERV 04/2016. \n' González-Buendía L; Di Lauro S; Pastor-Idoate S; Pastor Jimeno JC. Vitreorretinopatía proliferante (VRP) e inflamación: LA INFLAMACIÓN in «INMUNOMODULADORES Y ANTIINFLAMATORIOS: MÁS ALLÁ DE LOS CORTICOIDES. RELACION DE PONENCIAS DE LA SOCIEDAD ESPAÑOLA DE OFTALMOLOGIA. 10/2014.",institutionString:null,institution:null},{id:"243698",title:"Dr.",name:"Xiaogang",middleName:null,surname:"Wang",slug:"xiaogang-wang",fullName:"Xiaogang Wang",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/243698/images/system/243698.png",biography:"Dr. Xiaogang Wang, a faculty member of Shanxi Eye Hospital specializing in the treatment of cataract and retinal disease and a tutor for postgraduate students of Shanxi Medical University, worked in the COOL Lab as an international visiting scholar under the supervision of Dr. David Huang and Yali Jia from October 2012 through November 2013. Dr. Wang earned an MD from Shanxi Medical University and a Ph.D. from Shanghai Jiao Tong University. Dr. Wang was awarded two research project grants focused on multimodal optical coherence tomography imaging and deep learning in cataract and retinal disease, from the National Natural Science Foundation of China. He has published around 30 peer-reviewed journal papers and four book chapters and co-edited one book.",institutionString:null,institution:null},{id:"7227",title:"Dr.",name:"Hiroaki",middleName:null,surname:"Matsui",slug:"hiroaki-matsui",fullName:"Hiroaki Matsui",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Tokyo",country:{name:"Japan"}}},{id:"312999",title:"Dr.",name:"Bernard O.",middleName:null,surname:"Asimeng",slug:"bernard-o.-asimeng",fullName:"Bernard O. 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This will ensure that we discover ways to live in our world that allows us and other beings to flourish. We can no longer rely on medicalized approaches to health that wait for people to become ill before attempting to treat them. We need to live in harmony with nature and rediscover the beauty and balance in our everyday lives and surroundings, which contribute to our well-being and that of all other creatures on the planet. This topic will provide insights and knowledge into how to achieve this change in health care that is based on ecologically sustainable practices.
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