Emmanuel Drouet

Université Grenoble-Alpes

Expertise : Human Virology & Microbiology - NAME : DROUET Given name : Emmanuel Degree : PhD, PharmD Current position : Full Professor CEX1 Teaching & Education Professor at School of Pharmacy, UGA http://www.univ-grenoble-alpes.fr/en/ Research :Institut de Biologie Structurale (IBS), Univ. Grenoble Alpes, CEA, CNRS, http://www.ibs.fr/ Postal address CIBB-IBS 38044 Grenoble, France 71 Rue des Martyrs, 38000 Grenoble, France Principal investigator in more than 20 research projects in virology since 2000 Member of the CNU ('Conseil National des Universités” nominated by Ministère de l’Enseignement Supérieur et Recherche, France or French ministry of higher education and research, 87th section)) (2012-) – Expert at the AERES (Evaluation Agency for Research and Higher Education, France) Collaborations: University Medical Center, Utrecht (NL), University of Heidelberg (D) Research interest : Main activities : Research as group leader in the French Institution CNRS and european EMBL. Principal investigator in more than 20 research projects since 1994 Subjects : (i) Pathobiology of the viruses belonging to the Flaviviridae family (Hepatitis C Virus) (ii) Innovative diagnosis markers for Herpesviruses and immune response (iii) Virus- associated Cancers Teaching in Medical Microbiology (Bacteriology, Virology, and Immunity) (School of Pharmacy students of bachelor & master level) 5 main publications (key-words: Hepatitis C Virus, Epstein-Barr Virus, Cancer biomarkers) Habib M, et al., Morand P, Drouet E (2017) Lytic EBV infection investigated by detection of Soluble Epstein-Barr virus ZEBRA in the serum of patients with PTLD Nature Sci Rep 7: 10479 | DOI:10.1038/s41598-017-09798-7 1 Le Berre L, Rousse J, Gourraud PA, Imbert-Marcille BM, Salama A, Evanno G, Semana G, Nicot A, Dugast E, Guérif P, Adjaoud C, Freour T, Brouard S, Agbalika F, Marignier R, Brassat D, Laplaud DA, Drouet E, Van Pesch V, Soulillou JPDecrease of blood anti-α1,3 Galactose Abs levels in multiple sclerosis (MS) and clinically isolated syndrome (CIS) patients. Clin Immunol. 2017 Jul;180:128-135. Fallecker C, et al. Petit MA, Drouet E (2017) New insights into HCV replication in original cells from Aedes mosquitoes Virology Journal 14:161 DOI 10.1186/s12985-017-0828-z Souii A, Elargoubi A, Fallecker C, Mastouri M, Drouet EHepatitis C Genotype Prevalence in Monastir Region, Tunisia: Correlation between 5' Untranslated Region (5'UTR), Non-structural 5B (NS5B), and Core Sequences in HCV Subtyping. Curr Microbiol. 2016 Sep;73(3):324-334. doi: 10.1007/s00284-016-1064-2. Epub 2016 May 17. Marrão G, et al., Drouet E (2014). Epstein-Barr virus infection and clinical outcome in breast cancer patients correlate with immune cell TNF-α/IFN-γ response. BMC Cancer. Sep 11;14:665. doi: 10.1186/1471-2407-14-665 Pérard J, et al., Drouet E, Jamin M (2013). Structure of the full-length HCV IRES in solution. Nature Comm. 4: 1612. doi: 10.1038/ncomms2611 Rothe R, et al. Drouet E, Lenormand J-L. (2010). Characterization of the Cell-penetrating Properties of the Epstein-Barr Virus ZEBRA trans-Activator. J. Biol. Chem. 285:20224–20233. Book chapter (most recent) https://www.intechopen.com/online-first/the-role-of-the-epstein-barr-virus-lytic-cycle-in-tumor-progression-consequences-in-diagnosis-and-th