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Ponzio, Mili Mandal, Stella Elkabes, Pan Zhang, Junichi Sadoshima, Sayantani Basak, Peiyong Zhai and Robert Donnelly",authors:[{id:"158022",title:"Dr",name:null,middleName:null,surname:"Ponzio",fullName:"Ponzio",slug:"ponzio"}]},{id:"43452",title:"Valproic Acid in Autism Spectrum Disorder: From an Environmental Risk Factor to a Reliable Animal Model",slug:"valproic-acid-in-autism-spectrum-disorder-from-an-environmental-risk-factor-to-a-reliable-animal-mod",signatures:"Carmem Gottfried, Victorio Bambini-Junior, Diego Baronio, Geancarlo Zanatta, Roberta Bristot Silvestrin, Tamara Vaccaro and Rudimar Riesgo",authors:[{id:"31995",title:"Prof.",name:"Carmem",middleName:null,surname:"Gottfried",fullName:"Carmem Gottfried",slug:"carmem-gottfried"},{id:"43615",title:"Prof.",name:"Rudimar",middleName:null,surname:"Riesgo",fullName:"Rudimar Riesgo",slug:"rudimar-riesgo"},{id:"167294",title:"Prof.",name:"Victorio",middleName:null,surname:"Bambini-Junior",fullName:"Victorio Bambini-Junior",slug:"victorio-bambini-junior"},{id:"167295",title:"M.Sc.",name:"Diego",middleName:null,surname:"Baronio",fullName:"Diego Baronio",slug:"diego-baronio"},{id:"167296",title:"MSc.",name:"Geancarlo",middleName:null,surname:"Zanatta",fullName:"Geancarlo Zanatta",slug:"geancarlo-zanatta"},{id:"167297",title:"MSc.",name:"Roberta",middleName:null,surname:"Silvestrin",fullName:"Roberta Silvestrin",slug:"roberta-silvestrin"},{id:"167298",title:"MSc.",name:"Tamara",middleName:null,surname:"Vaccaro",fullName:"Tamara Vaccaro",slug:"tamara-vaccaro"}]},{id:"43451",title:"Mnesic Imbalance or Hyperthymestic Syndrome as Cause of Autism Symptoms in Shereshevskii",slug:"mnesic-imbalance-or-hyperthymestic-syndrome-as-cause-of-autism-symptoms-in-shereshevskii",signatures:"Miguel Ángel Romero-Munguía",authors:[{id:"32986",title:"Dr.",name:"Miguel Ángel",middleName:null,surname:"Romero-Munguía",fullName:"Miguel Ángel Romero-Munguía",slug:"miguel-angel-romero-munguia"}]},{id:"43450",title:"Genetic Evaluation of Individuals with Autism Spectrum Disorders",slug:"genetic-evaluation-of-individuals-with-autism-spectrum-disorders",signatures:"Eric C. 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Urbano, Kathrin Hartmann, Stephen I. Deutsch, Gina M. 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O’Malley, Susan D. Rich",authors:[{id:"155711",title:"Dr.",name:"Kieran D.",middleName:null,surname:"O'Malley",fullName:"Kieran D. O'Malley",slug:"kieran-d.-o'malley"}]},{id:"43427",title:"Autism Spectrum Disorders in People with Sensory and Intellectual Disabilities Symptom Overlap and Differentiating Characteristics",slug:"autism-spectrum-disorders-in-people-with-sensory-and-intellectual-disabilities-symptom-overlap-and-d",signatures:"Gitta De Vaan, Mathijs P.J. Vervloed, Harry Knoors and Ludo Verhoeven",authors:[{id:"156051",title:"M.Sc.",name:"Gitta",middleName:null,surname:"De Vaan",fullName:"Gitta De Vaan",slug:"gitta-de-vaan"},{id:"157224",title:"Dr.",name:"Mathijs",middleName:null,surname:"Vervloed",fullName:"Mathijs Vervloed",slug:"mathijs-vervloed"},{id:"166523",title:"Prof.",name:"Harry",middleName:null,surname:"Knoors",fullName:"Harry Knoors",slug:"harry-knoors"},{id:"166524",title:"Prof.",name:"Ludo",middleName:null,surname:"Verhoeven",fullName:"Ludo Verhoeven",slug:"ludo-verhoeven"}]},{id:"43421",title:"Empowering Families in the Treatment of Autism",slug:"empowering-families-in-the-treatment-of-autism",signatures:"Jennifer Elder",authors:[{id:"156987",title:"Dr.",name:"Jennifer",middleName:null,surname:"Elder",fullName:"Jennifer Elder",slug:"jennifer-elder"}]},{id:"43419",title:"Collaboration Between Parents of Children with Autism Spectrum Disorders and Mental Health Professionals",slug:"collaboration-between-parents-of-children-with-autism-spectrum-disorders-and-mental-health-professio",signatures:"Efrosini Kalyva",authors:[{id:"158901",title:"Dr.",name:"Efrosini",middleName:null,surname:"Kalyva",fullName:"Efrosini Kalyva",slug:"efrosini-kalyva"}]},{id:"43417",title:"Early Intensive Behavioural Intervention in Autism Spectrum Disorders",slug:"early-intensive-behavioural-intervention-in-autism-spectrum-disorders",signatures:"Olive Healy and Sinéad Lydon",authors:[{id:"156296",title:"Dr.",name:"Olive",middleName:null,surname:"Healy",fullName:"Olive Healy",slug:"olive-healy"}]},{id:"43414",title:"Feeding Issues Associated with the Autism Spectrum Disorders",slug:"feeding-issues-associated-with-the-autism-spectrum-disorders",signatures:"Geneviève Nadon, Debbie Feldman and Erika Gisel",authors:[{id:"157283",title:"Dr.",name:"Erika",middleName:"G",surname:"Gisel",fullName:"Erika Gisel",slug:"erika-gisel"},{id:"157379",title:"M.Sc.",name:"Genevieve",middleName:null,surname:"Nadon",fullName:"Genevieve Nadon",slug:"genevieve-nadon"}]},{id:"42649",title:"Clinical Approach in Autism: Management and Treatment",slug:"clinical-approach-in-autism-management-and-treatment",signatures:"Rudimar Riesgo, Carmem Gottfried and Michele Becker",authors:[{id:"31995",title:"Prof.",name:"Carmem",middleName:null,surname:"Gottfried",fullName:"Carmem Gottfried",slug:"carmem-gottfried"},{id:"43615",title:"Prof.",name:"Rudimar",middleName:null,surname:"Riesgo",fullName:"Rudimar Riesgo",slug:"rudimar-riesgo"},{id:"160959",title:"Dr.",name:"Michele",middleName:null,surname:"Becker",fullName:"Michele Becker",slug:"michele-becker"}]},{id:"43411",title:"Building an Alternative Communication System for Literacy of Children with Autism (SCALA) with Context-Centered Design of 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The aim of this integration is to achieve and provide high-efficiency thermal comfort or natural lighting. Passive system performances depend mostly on natural and environmental elements like the sun, wind, earth, and water. It is, therefore, significant to study and analyze how passive systems interact with natural elements and their relationship to a building site. Passive cooling systems, thereafter, need to be integrated within the design process, as their performance requirements are affected by orientation, height, materials, form, and characteristics of many architectural elements.
\nThe main two innovative ideas of this chapter are, first, to provide analysis of passive devices based on one or more of the cooling actions (store, avoid, remove, and slow (SARS)) and, second, to develop a design matrix based on SARS actions and analysis of examples of integrated passive systems.
\nPassive cooling systems were the main design driver in low energy architecture and vernacular architecture especially in hot climate regions. Buildings were designed and built to adapt to local environmental conditions and to use natural elements to provide occupants with the required thermal comfort around the year. However, the discovery of fossil fuels and the development of new construction materials the building industry became less respect to the surrounding environment and less dependent on passive techniques. Buildings become heavily dependent on energy to provide the indoor environment with the required thermal comfort. The use of fossil fuels on a large spreader scale resulted on many environmental and health problems that associated with the greenhouse emissions. These problems shifted architects’ awareness to environmental and climatic variables to be key drivers of the building design to provide the required thermal comfort and reduce energy consumptions.
\nPassive cooling or heating approaches play a major role in bringing architecture closer to the original green, environmental, and vernacular architecture by using surrounding environmental elements such as solar radiation and natural ventilation. Passive cooling is an approach that focuses on providing thermal comfort by controlling heat gains and heat dissipation without involving mechanical or electrical devices. The performance quality of this approach depends totally on the interaction of the building’s design and devices with the surrounding environmental factors, such as sun rays, ambient air temperature, wind, and humidity, to achieve energy balance for occupants. Therefore, conducting a thorough analysis of a building’s local climatic conditions is essential for any passive cooling approach to successfully fulfill its purpose and to maximize a specific action of SARS.
\nHeat gain sources include internal and external sources. The internal heat gains are produced from human activities, artificial lights, equipment, and appliances used by the occupants, while the external heat gains result from the interaction of the building with the outdoor environment. Heat gain or loss has four forms:
The interaction of the building with the environmental elements (author).
Lechner [1] presented many simple passive devices used for cooling in hot climates like simple courtyard, wind tower, thermal massing, windows, arcade, shading devices, and solar chimney. In addition the book discussed the ventilation principles and pattern. Many studies investigated in different approaches and methods the potential of passive cooling techniques in saving energy and cooling the indoor space in different climates. Nunes and Oliveira Panão [2] suggested a method to calculate the monthly cooling energy needs in zones where passive cooling systems are installed and applied on an office ventilated by passive devices like earth cooling and solar chimney. Kachkouch et al. [3] investigated three passive techniques in the real conditions in hot semiarid climate. The study tested the effect of three main techniques are, shading ceiling color and insulation on heat flux. The study concluded that these techniques helped to reduce heat flux with best results of white painted. Prieto et al. [4] showed how important it is to apply the passive strategies in early design stages and use active equipment after that if necessary. They studied, using simulation software, the effectiveness of selected passive cooling strategies like glazing, shading, color, and heat sink in commercial buildings in warm climates. The study concluded that the efficiency of the passive strategies conditioned to both the harshness of a given climate and design of different building parameters. Tejero-González et al. [5] reviewed many passive design techniques and parameters affecting applicability of such techniques. The study investigated how the climatic parameters are needed to be studied thoroughly to design and select passive cooling/heating techniques. Panchabikesan et al. [6] studied many passive design techniques like evaporative cooling, nocturnal radiative cooling, and phase change material (PCM) in different climatic conditions in India to reduce energy consumption. The study showed that these techniques best result in hot climates. Oropeza-Perez and Østergaard [7] review many passive and active cooling methods that could be used in residential buildings. They studied firstly many technologies in term of heat balance, secondly they scientifically analyzed the results, and finally they focused on feasibility and economic value of the findings. The study developed a decision-making program to find out the most suitable cooling method in dwelling design. Passive cooling focuses on controlling heat gain or heat loss in a building in order to reduce energy consumption and in order to create the indoor thermal comfort [8].
\nUnderstanding the sources of heat gains that affect thermal comfort in the building is essential for deciding the type of actions to be taken to avoid as much heat gains as possible, to slow the heating process to remove the uncontrolled gained heat, or to store cold air or elements. The four passive cooling actions include the following:
The four actions of passive cooling,
The required actions of implementation from designers in each design process, in stages of early stage (analysis), middle stage (design), and final stage (performance)
The building variables related to the devices and principles
The required conditions of using the device
Using case studies and examples of integration of devices and actions in the buildings’ design
Some passive systems have direct impact on the architecture design, like the design of an opened atrium or a courtyard, and some have less direct influence, like the type of material and use of louvers or shading systems. Therefore, the level of integration between these systems and the architectural elements varies among the different types of systems and actions. However, it is important to understand the requirements of the chosen passive systems and to make the right decisions of when and where to integrate them within the designing process.
\nStoring refers to keep cold air or low temperature object away from direct heat sources to be used to cool down interior spaces. Throughout architectural history, and particularly in hot climate regions, devices were developed for this purpose as storage design elements, like courtyards, earth spaces, basements combined with wind towers, thermal masses, and sunken courtyards. For the purpose of this research, courtyards are discussed as one of the most efficient devices in storing cold objects or air.
\nCourtyard is an opened space surrounded by rooms with openings on the conjoint wall between the rooms and the courtyard space, to allow air exchange daylight, and view. The courtyard as passive design device works as a modifier of the microclimate and acts as a heat sink and cold air storage. Buildings with internal courtyards are characterized as a suitable solution for cooling in hot climate regions to provide inner spaces with cold air and daylight.
\nThe working mechanism of the courtyard depends on the cycle of day and night, which results on a continuous change of air temperature and the difference in air temperature between the inside and outside of the courtyard (Figure 2). Therefore the performance quality of the courtyard house depends on the heat exchange processes between the indoor spaces and the courtyard and then between the courtyard space and the external open spaces. It consists of three main periods; during the first one, the cool night air sinks into the courtyard and flows to the surrounding rooms, and therefore the spaces and surfaces are cooled until noon time. During this period, the courtyard works as storage of cold air and cold air exchange with surrounding rooms. The second period starts at noon, when the sun strikes the floor of the courtyard directly and the temperature of air inside the court’s space starts increasing gradually, causing the hot air to move up, and consequently, air is drawn from surrounding rooms to the courtyard space through the openings, resulting in cooling the surrounding rooms. The last period starts when the courtyard and the surrounding rooms get warmer, and all cool air leaks out, which prepares the system for a new cycle in the next day.
\nThe three periods in the working mechanism of a courtyard (author).
The passive cooling performance of courtyards depends on three types of elements: the courtyard elements like walls, floor, and landscape greeneries; building elements like windows and built space characteristics; and finally site elements like location, climate, and orientation as summarized in Table 1. The cooling performance of courtyards depends on providing the enclosed spaces protection from direct solar radiation and controlled airflow by studying the orientation of the courtyard with regard to the solar path and providing trees for shades and designing with consideration of prevailing winds. Table 1 summarizes the different variables affecting the cooling performance of a courtyard that designers need to take in consideration in the designing process:
\nElements | \nVariables | \nHow to maximize storing action in hot climate | \n
---|---|---|
Walls, floor | \nHeight-to-width or to area ratio | \nHigh H/W ratio [11] | \n
Material, thickness, color | \nHigh thermal mass stores low temperature, heat absorbance, and reflection | \n|
Geometrical shape | \nInside stepped or tilted walls [27] | \nIncreases the shaded areas and improves courtyard’s thermal performance and storing action in hot regions | \n
Outside stepped or tilted [27] | \nIncreases surface exposure to sun and therefore reduces the shaded areas | \n|
Landscape | \nGreenery type, height | \nDefine the patterns of shade or expose shaded area on floor and walls | \n
Windows | \nLocation, window/wall ratio | \nAs the openings allow air to be drawn from the rooms to the courtyard | \n
Orientation | \nNorth–south or west–east | \nA balance based on prevailing winds and solar angles, to optimize shading and ventilation | \n
Courtyard design variables (author).
Optimizing the passive cooling performance of courtyards in hot regions depends mainly on how to design an efficient storage space by studying shading patterns, geometrical shape, and thermal mass material.
\nZamani et al. [9] studied how to improve the thermal performance of the courtyard by studying various design factors such as proportion, orientation, geometry, opening characteristics, and material. In addition they studied more variables like shading devices, vegetation, and water pools and their impact on heat mitigation.
\nSadafi et al. [10] explained how using internal courtyards in terraced houses in tropical regions improves the natural ventilation and thermal comfort. Meir et al. [11] investigated how two semi-enclosed attached courtyards will affect the microclimate in the enclosed courtyards and the attached built volume. Muhaisen [12] showed that courtyards’ shading performance depends on the form’s properties, location, latitude, and available climatic conditions. Berkovic et al. [13] studied the effect of courtyard design variables, like orientation, horizontal shadings, galleries, and trees, on the thermal comfort of the courtyard’s surrounding functions. Muhaisen and Gadi [14] investigated how courtyards’ proportions and surface colors considerably influence thermal comfort of the surrounding spaces. Al-dawoud and Clark [15] investigated how different design parameters of the courtyard affect the thermal comfort in spaces surrounding the courtyard. They approved that courtyards are more energy efficient in hot-dry and hot-humid climates in comparison to cold climates.
\nThe design of courtyard with other devices and elements should be made to enhance storing effect and ventilation process, which include the opening, thermal mass, landscape, and building form. Elements that could be integrated should enhance storing action of the courtyard like thermal mass, wall geometry, and landscape. Moreover, to enhance heat exchange between the courtyard and surrounding spaces, other devices could be integrated with the courtyards like wind tower, solar chimney, basement, and opening design and bearing in mind the design requirements in early stages of design process. Therefore, design decisions will have direct impacts on the building’s form, orientation, area, zoning, function distribution, and relations with the outdoor and site design.
\nAvoidance, as a passive cooling action, refers to all the methods used to prevent and reduce the amounts of heat gains from direct solar radiation or wind. The key methods of avoidance include different shading devices, building’s form, and landscape. Additional factors, including building’s orientations and surfaces’ colors and textures, can help to prevent gained heat from reaching inner spaces.
\nCho et al. [16] presented an integrated approach for exterior shading device design analysis that included cooling energy performance and economic feasibility in high-rise residential buildings. The research investigated the effect of 48 exterior shading devices on the sunshading/daylighting performance. Palmero-Marrero and OLiveira [17] studied the effect of static louver shading devices on east, west, and south facades for various locations on the energy demands during cooling and heating seasons. The research concluded that the shading device reduced the total annual energy demands in buildings of countries with long dominant cooling seasons and high ambient temperatures and solar radiation.
\nDatta [18] studied the effect of external fixed horizontal louvers on the thermal performance in the buildings. The study was aimed for reducing the overall energy requirements for the entire year by maximizing the shading device system to reduce solar gains during summer and allow them during winter. The study used TRNSYS as a simulation to maximize the efficiency of the device, and different slat lengths and tilt angles were tested in four Italian cities. Yao [19] evaluated the effect of shading control strategies on the daylighting, visual comfort, and energy performance in buildings.
\nDesigning buildings with the passive approach requires integration of many factors together in the process, such as orientation, shading devices, and building form in order to reduce energy consumption in the building as a whole as seen in Table 2. Largely glazed facades and large windows have been increasingly used in new buildings, allowing access to daylight, solar heat gains, and external views. The increase in glazed surfaces requires significant attention in building design, regarding the impact they have on cooling, heating, and lighting loads demands. Therefore, it is important to provide these buildings with a proper shading design that would provide interior spaces with thermal comfort by controlling solar heat gains and reducing glare while maintaining the initial purpose of large glazed surfaces to provide external views and sufficient daylighting.
\nElements | \nVariables | \nHow to maximize avoidance actions | \n
---|---|---|
Types by | \nHorizontal louvers | \nSouthern windows block high solar angles | \n
Vertical louvers | \nEast and west windows block low solar angels | \n|
Diagonal or eggcrate | \nBlock low and high angles on east, south, and west directions | \n|
Overhangs, canopy | \nThe depth and height, considering solar noon in summer and winter | \n|
Device’s variables | \nSpace to depth | \nDepth-to-spacing ratio to balance between sunrays block and view out | \n
Material | \nTo reflect or to absorb sunrays | \n
Shading device variables (author).
Many researches were conducted to study the performance of shading devices in order to optimize their performance, save energy, and achieve the maximum thermal comfort. Datta [18] used computer simulation to study variables related to horizontal shading devices and their effect on the thermal performance in buildings in Italy. The study showed that shading devices could help save energy and improve the thermal performance of the buildings. Palmero-Marrero and OLiveira [17] proved that shading devices could improve thermal performance of buildings and save energy in many cities in different latitudes and climatic conditions.
\nA study that has been conducted at Jordan University of Science and Technology to design shading devices showed that the process of designing shading devices for an existing building required reflections of various parameters besides thermal comfort. Many tools were used to monitor the performance of shading devices like patterns of use and users’ behavior in the new setting. The study used real measurements, computer simulation, user’s survey, and observation usage. The study showed that user’s preferences like view out, natural lighting, illuminance levels, and thermal comfort were the most influential indicators in designing shading devices. Moreover, user’s behavior and patterns of use in the office in question were monitored and proved that a well-designed shading device can improve thermal comfort, user satisfaction, and user behavior from energy consumption point of view. The study was conducted in two stages: in the first stage, temporary materials were used to study the integration of all variables as seen in Figure 3. In the second stage, permanent materials were used, and long-term monitoring was conducted in order to generalize the best design for shading devices in offices with large windows at the university campus [20].
\nStages of designing shading devices in the existing building and their performance with reference to users’ preferences [
Hemsath and Alagheband Bandhosseini [21] stated that building form and orientation as early decisions in the design process could have a great impact on energy consumption, lighting, cooling, and heating load. Authors emphasized on the relation between the building’s forms, shapes, daylight, and energy consumption in the early design phase, instead of using mechanical and artificial light. Many non-rectangular shapes had been evaluated in terms of self-shading and energy consumption like an L or U shape that can offer solar advantages. Zhou et al. [22] studied how optimal building design could enable harvesting of the maximal micro-wind power around low-rise residential buildings.
\nZerefos et al. [23] compared polygonal and prismatic building envelopes to orthogonal building envelopes based on energy behavior and energy consumption in Mediterranean climates. The study showed that prismatic formed buildings gain lower solar than orthogonal forms and so consume less energy by an average of 7.88%. Moreover, Caruso et al. [24] used the mathematical theory of calculus of variation to find the best geometric form to minimize direct solar irradiation incident on the envelope. The paper also aimed at finding useful guidelines and rules for designers to follow during early decision-making stages to reduce the total amount of direct solar irradiation [24].
\nAzari et al. [25] showed that there are various architectural features of a building that could influence its indoor thermal comfort, daylight, and energy consumption, such as building shape, orientation, wall forms, window-to-wall area ratio, window size, glazing material, wall structure, and shading. They may increase solar gain and daylight duration during winter, which would be beneficial and could lead to overheating during summer. Yasa [26] studied the comfort conditions of different configurations of buildings like open courtyard configurations, closed courtyard configurations, and configurations of courtyards with apertures on the wall.
\nDesigners can use building’s forms as self-shading approach that shades the outside surface materials, windows, and glazed areas (Table 3). An example of a self-shading building is the library of the University of Nottingham, UK, which was designed with large glazing surfaces to utilize daylighting without causing glare as seen in Figure 4. The design was based on using self-shading form to protect inner spaces from direct sunrays.
\nElement’s construct | \nConcepts | \nVariables | \nNotes | \n
---|---|---|---|
Building’s elements | \nExterior wall tilt angle | \nWinter and summer solar angle | \nStudying the maximum and minimum solar angles to determine the optimum tilt angle of the external walls for the building to act as self-shading form | \n
Site’s elements | \nClimate | \nHot climates | \nSelf-shading forms for buildings with large glazed surfaces and high requirements of daylighting | \n
Cold climates | \nRequires less self-shading forms and increase of the direct heat gains | \n
Self-shading and building form variables.
Library building at University of Nottingham, UK (author).
Trees and landscape can improve the thermal environment and reduce the temperatures of interior spaces and surfaces in buildings. Monitoring tree effects on buildings showed that trees and landscapes do not only provide shade and reduce air temperature but also prevent buildings’ materials from gaining and storing heat and radiating it back later as seen in Table 4. A study conducted in Jordan University of Science and Technology compared two identical glazed corridors of orientation and materials, but one of them with trees and landscape providing shade, and one without trees. The study showed that shaded building’s surfaces with high trees recoded a lower temperature of 34°C than identical spaces with temperature of 41°C in summer day as seen in Figure 5.
\nVariables | \nNotes | \n
---|---|
Tree type | \nEvergreen or deciduous trees affect the periods and area of shading on buildings, walls, courtyards, and outdoor spaces in summer and winter | \n
Height and horizontal spread | \nThe pattern of shade provided by different types of trees | \n
Distance from building | \nLocation of shade on building, walls, walking area, and courtyards | \n
Landscape variables (author).
The effects of trees on surface and air temperatures in identical spaces (author).
Designing with avoidance systems requires analysis of the solar angles laterally with the dimensions and orientation of the building’s site to identify the type of shading devices with integration and function and daylight strategies. Designer’s decision of the building’s form should consider self-shading building, orientation, elevation design, and relation to landscape to enhance avoidance actions. Performance evaluation of avoidance actions required integration of cooling decisions with all building elements, such as glazing area, orientation form and mass design, facade design, and opening.
\nRemoving, as a passive cooling action, refers to the removal of undesirable gained heat in interior or exterior spaces in a building. Natural ventilation normally is the main strategy used to take unwanted heat out of the buildings. It depends mostly on pressure differences to circulate air between inner and outer spaces, allowing air to enter or escape from buildings. Devices like windows, openings, wind towers, sunspaces, earth tunnels, and roof openings are used to move air through a building.
\nNatural ventilation follows three main principles that designers should understand well in order to induce passive ventilation into any building’s design, which includes stack ventilation, Bernoulli’s effect, and the Venturi effect. These three principles uses air pressure differences due to height, air temperature, or wind speed, to pull air to or from buildings. Therefore, the main concept of passive ventilation design is achieved by maximizing the use of one or more of the three principles in order to induce natural ventilation.
\nStack effect depends on temperature differences to circulate air, as hot air rises up and cool air sinks down (Figure 6). The design for ventilation that depends on stack principles is achieved by letting hot air rise up within spaces or specific devices and exhausting it from upper openings, which allows it to be replaced by cooler air from lower openings. The designer’s role in the process is represented in designing air movement and its exhaustion and penetration, which includes the following methods:
Accelerating the rising of hot air by designing a long vertical space that crosses through the building section, like atriums, double-skin facades, solar chimneys, or wind towers
Designing inlet openings for cold air to enter the building from a well-planned and controlled cold space like shaded courtyards or urban spaces, basements, etc.
Increasing warm air to activate the stack effect and accelerate the ventilation process using devices like sunspaces, solar chimneys, and skylights in the building’s design
Stack effect (author).
Bernoulli’s effect depends on the reduction of air pressure associated with the wind speed. In buildings, designers use wind speed differences to circulate air inside or around the building Figure 7. Air movement around and above buildings creates positive and negative pressures, causing fresh air to be sucked through specific openings into the buildings at the same time allowing hot air to escape though designate openings and locations. The designer’s role in the process is represented in planning and designing air movements with regard to the negative and positive air pressures zones, and it includes the following methods:
Designing the building’s surroundings with the least possible obstructions to allow air flow around, creating the necessary positive and negative pressure zones.
Designing the building’s form to go with the direction of the wind rather than obstructing it; this is to increase wind speed around the building and create positive and negative pressures.
Designing openings in the areas of positive and negative pressures with integration with the interior space distributions to maximize ventilation process.
Bernoulli’s effect (author).
Venturi effect causes acceleration in air speed when it passes from a wide section area to a thinner section area, developing a negative pressure zone at the thinning points, which help suck the air from near spaces as seen in Figure 8. Designers can make use of this effect in building’s designs by:
Designing urban settings, landscape, and group buildings with regard to the large scale to allow them to capture wind and increase its speed
Using upper openings in atriums and skylights to improve the performance of the effect
Using elements like ventilation ducts and pipes to improve the performance of the effect
Venturi effect (author).
Wind towers are used to catch air from higher levels and push it into the interior spaces of a building. A cooling process takes place by heat exchange between the walls of the tower and the hot collected air or by using evaporative cooling at the bottom of the wind tower. Fresh cold air flows to the inner spaces through an opening at the end of the wind tower. At night, wind tower works as a chimney to suck the hot and exhausted air from the room to the outside environment, causing cooler air to replace hot air from other openings. The performance of wind towers can be improved by implementing a water source, like a fountain, at the bottom of the wind tower, which helps cool the gathered air. Additionally, the wind tower can be combined with courtyards and underground tunnels to increase the cooling process of the collected air. A wind tower operates in various ways depending on different factors like the time of day, the presence or absence of wind, and the difference of air temperature inside and outside the building (Table 5). The fundamental principle of wind tower operation system lies in changing the temperature of the air inside the tower, therefore changing the density, which is a key factor in circulating air and improving the device’s performance.
\nElement’s construct | \nVariables | \nNotes | \n
---|---|---|
Device’s elements | \nOrientation | \nThe openings to be orientated toward the wind | \n
Height | \nAffects the wind speed entering the tower and building and heat absorption by menials | \n|
Material | \nThermal mass material cooled hot air | \n|
Inlet opening | \nThe size of inlet and outlet openings affects the amount of collected winds, its speed in the tower itself, and its speed as it enters spaces | \n|
Outlet openings | \n||
Integration with inner spaces | \nAffects the patterns of air distribution inside the building | \n
Wind tower variables (author).
Solar chimney helps to increase the airflow from interior to upper level and to be replaced by cold air from outdoor shaded area like courtyards or basements.
\nSlowing, as a passive cooling action, refers to the reduction of heat transfer through the building’s surfaces by conduction. It depends on the interaction of the building’s envelope with the outdoor environment by receiving and absorbing heat and then transferring it to the inner spaces. The performance of slowing as a cooling action depends on many key factors in the building’s envelope, such as thermal insulation, thermal masses, building’s volume-to-surface area ratio, building materials, and double glazing. These variables control the amount of heat transfer from outdoor environment to inner spaces and therefore reduce the need for heat removal and the associated cooling loads.
\nThe two main factors designers should take into consideration when choosing a thermal mass material and surface are
where QA = thickness × density × specific heat and R = thickness/conductivity.
\nIn calculating the TTC per area, (TTCA) for a composite wall, the QA × R of each layer, including the outside and inside air film layers, is calculated in sequence, and they are calculated for each layer from the external wall to the center of the section in question. A high value of TTC means a high thermal inertia of the building, and it results in a low interior temperature swings. The
Optimizing the performance of passive cooling devices and techniques can be achieved by identifying their relation to building design process, where these devices can be implemented and integrated with other architectural and cooling elements to accomplish more than one function. This integration encourages designers to take into consideration the implementation of passive cooling devices and techniques as an integrated stage within the designing process, like analysis, planning, and evaluation stages.
and strategies in the early stage (analysis) of the design process give the passive cooling an essential part in the design performance values. Considering such strategies as design variables will develop building design and create integrated relations between architectural elements and passive cooling devices. Therefore, find creative solutions for passive cooling, and improve the performance of traditional techniques to be easily practiced in modern designs. In addition, considering cooling performance of a building under the designing process as performance criteria in building design process will help designers reevaluate their decisions on passive cooling performance. To do so, computer simulation software can be used to identify which decisions, devices, and variables need to be reviewed during the evaluation stage.
\nCombining more than one device or principle of passive cooling in building design requires designers to consider passive cooling strategies in all designing processes. The integrated design will create cooling strategies that have a significant and direct impact on building form, plans, sections, and functional distribution, and user’s interaction and behavior in the building as seen in (Figure 9). Therefore, an integrated building design approach is needed to make the architectural systems, passive cooling systems, and active systems work together within a complete integrated framework to improve performance and save energy, as cooling loads can be minimized through environmental designs that involve judicious use and implementation of shading devices, vegetation, colors, materials, and insulation.
\nExample of integration of storage devices and removal devices: (1) combining wind tower with base ment, (2)combining solar chimney with courtyards, and (3) combining two courtyard sunny with shaded one (author).
This paper presents a guideline for implementing passive cooling systems and devices by discussing the four passive cooling actions, which designers should take into consideration in the process of creating a building. It discusses the various variables affecting each device within each action, and it explains in details the major issues that need to be considered for each device and action in the three design stages of any building. This integration of passive cooling principles in the design stages represents a new invention in architectural technology and a guideline of passive cooling design for designers and architects. Table 6 summarizes the required passive cooling actions and design solution that are used to minimize the effects of various heat sources and their implementation considerations in each of the three design stages.
\nSources of heat | \nActions required | \nDesign solution | \nDesign stage | \n
---|---|---|---|
Direct heat gain from solar radiation on building envelope materials | \nAvoidance | \n\n
| \n\n
| \n
Slowing | \n\n
| \n\n
| \n|
Direct heat gain from solar radiation on windows and glazed surfaces | \nAvoidance | \n\n
| \n\n
| \n
Slowing | \n\n
| \n\n
| \n|
Indirect heat gain by conduction with outdoor environment through building envelope | \nAvoidance | \n\n
| \n\n
| \n
Slowing | \n\n
| \n\n
| \n|
Removal | \n\n
| \n\n
| \n|
Indirect heat gain by convection through the ventilation and infiltration currents | \nAvoidance | \n\n
| \n\n
| \n
Slowing | \n\n
| \n\n
| \n|
Internal heat gains by human activities, equipment, machines, and lighting | \nRemoval | \n\n
| \n\n
| \n
Avoidance | \n\n
| \n\n
| \n
Design matrix in relation to cooling actions (author).
The combination of two principles or devices will be discussed in a way to improve performance, increase efficiency, and integrate devices with building design. Many devices can be combined together to perform more than one function and shift cooling and passive design to be as a comprehensive and integrated design approach. The momentum of passive and green architecture helps to develop new devices that perform more functions and help other devices to perform better.
\nThe design process of such composite design required multi-dimensional analysis of each device and how it could be integrated with other devices.
Analysis stage: for each device the working mechanism and condition required to perform well should be thoroughly analyzed.
Design stages: design the devices to perform more than one function. In addition design the device to improve the function of other devices
Performance stage: reevaluate the integration between devices and architectural systems and how they performed together using experiments or computer simulations.
The following discussion will show how some devices have been integrated and designed with other devices to improve their performance and to become as innovative passive design approaches.
\nThe design of wall geometries of the courtyard could help to improve its cooling performance. Freewan [27] showed that the design of wall geometries helps to control direct incident of sunrays on the courtyard’s floor, reduce glare, and improve both daylight quality and quantity. It helped to reduce heat gain from artificial light as it introduces daylight from shaded area. The study showed how wall geometries increase the shading area and time and therefore help to store cold air for long time to ventilate inner spaces with fresh cold air. These configurations as seen in Table 7 improved courtyard design especially in regions with hot and clear sky [27].
\nCourtyard configurations [27].
Advanced and modern wind towers were used in university building at the University of Nottingham to be cooling and daylighting devices. They were developed to have rotatable head to maximize the efficiency. The new wind towers were designed in integration with atrium and opening figure. The towers were used as wind tower, stairs, daylight devices with large glazed area at top part. They were designed with integration with atrium for maximum performance Figure 10.
\nCombining wind catcher with atrium and daylight elements (author).
A study [28] has been conducted at Jordan University of Science and Technology to design adjustable shading devices for existing and new buildings in mild climate with hot summer and cold winter. The research aimed at designing optimized double-positioned external shading device systems that help to reduce energy consumption in buildings and provide thermal and visual comfort during both hot and cold seasons. The design was based on comparison of performance of many variables to determine the best fit characteristics for two positions of adjustable horizontal louvers on south facade or vertical fins on east and west facades for summer and winter conditions. The adjustable shading systems can be applied for new or retrofitted office or housing buildings. The optimized shading devices for summer and winter positions helped to reduce the net annual energy consumption compared to a base case space with no shading device or with curtains and compared to fix shading devices.
\nFreewan and Abdallah [29] studied integration of many devices to improve ventilation process in university classrooms. The study showed that integration of wind tower with side windows or side horizontal ventilation duct with side windows helped to improve the natural ventilation in classrooms, activate stack effect, and increase the air velocity (Figure 11).
\nIntegration of windows with wind tower and horizontal duct.
Freewan [30] studied how the building’s form and wall geometries could help to reduce energy consumption and improve thermal and visual comfort. Inward and outward tilted south and north facing facades were studied in the study. Thermal energy performance and daylighting were investigated for many inward and outward angles for both south and north directions. The tilted configurations were achieved as an acceptable balance between cooling, heating energy consumption, and daylighting performance and compared to vertical facades to provide best solar shading, energy consumption, and daylight performance. Many variables were monitored and studied like self-shading, time and period of exposure to sun rays, and how the tilted facade performed. The results showed outward tilted facades for the south orientation performed well as they reduced cooling load and improve both daylight quality and quantity. On the other hand, inward facades for north orientation performed well in terms of daylight compared to vertical facade (Table 8).
\nForm configurations [30].
Wind tower as ventilation and heat removing tools was integrated with courtyard or basement to increase airflow rate and bring cold air to be stored. Configurations like these can be found in Iraq and Egypt, which help activate the stack effect to circulate the cold air to the occupied spaces (Figure 12). In modern design wind tower can be integrated with wind tunnel as the wind tower is used to circulate the air, while the tunnel is used to cool the air.
\nCombining wind towers with courtyards and basements (author).
In Beddington Zero Energy Development (BedZED) in the UK, wind catchers with routable head were designed in integration with the buildings’ form, sun space, space articulation, and functional zoning (Figure 13). The BedZED climatic design was based on more than ventilation principles.
\nBedZED design and wind catcher (author).
Shading devices and light shelf were studied to be integrated with ceiling geometries in order to maximize shading and daylight performance in hot climate to save energy (Figure 14). Many ceiling geometries were investigated to find maximum daylight performance while keeping the optimum shading effects [31, 32].
\nCombing shading devices with ceiling geometries [
Light pipe is an advanced daylighting technology used to bring light to a space with no direct contact to outside. It is a cylindrical tube connected to a collecting unit and a diffusing unit. The literature review shows that many researchers have studied the light pipe. Elmualim et al. [33] used dichroic material to develop the light pipe’s performance as an integrated system for daylighting and ventilation. The integration is based on using two concentric channels for both daylighting and natural ventilation; the inner one will guide sunlight and daylight into occupied spaces, while the outer one enables passive stack ventilation (Figure 15).
\nWorking mechanism of light pipe as daylighting devices and ventilation devices (author).
Implementing passive cooling systems in building design has many advantages over using the fossil fuel-based cooling systems, as they produce no environmental impacts and GHG emissions. The implementation of passive cooling devices in any building design requires many considerations and analyzation of the various variables affecting the cooling performance, and these considerations need to be taken from the earliest design stages and not only at the end of the architectural project, to allow these systems to reach the fullest possible potentials and to be integrated within the design itself, rather than being an additional solution that is forced into a building.
\nThis chapter represented a guideline and innovations in building design process on a comprehensive level that take into consideration the four passive cooling actions,
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Later, he completed his postdoctoral research at the Center of Molecular Biosciences, University of the Ryukyus, Japan, as a recipient of the Japan Society for the Promotion of Science (JSPS) postdoctoral fellowship. He was also the recipient of the Australian Government Endeavour Research Fellowship for postdoctoral research as an adjunct senior researcher at the University of Tasmania, Australia. Dr. Hasanuzzaman’s current work is focused on the physiological and molecular mechanisms of environmental stress tolerance. Dr. Hasanuzzaman has published more than 150 articles in peer-reviewed journals. He has edited ten books and written more than forty book chapters on important aspects of plant physiology, plant stress tolerance, and crop production. According to Scopus, Dr. Hasanuzzaman’s publications have received more than 10,500 citations with an h-index of 53. He has been named a Highly Cited Researcher by Clarivate. He is an editor and reviewer for more than fifty peer-reviewed international journals and was a recipient of the “Publons Peer Review Award” in 2017, 2018, and 2019. He has been honored by different authorities for his outstanding performance in various fields like research and education, and he has received the World Academy of Science Young Scientist Award (2014) and the University Grants Commission (UGC) Award 2018. He is a fellow of the Bangladesh Academy of Sciences (BAS) and the Royal Society of Biology.",institutionString:"Sher-e-Bangla Agricultural University",institution:{name:"Sher-e-Bangla Agricultural University",country:{name:"Bangladesh"}}},{id:"187859",title:"Prof.",name:"Kusal",middleName:"K.",surname:"Das",slug:"kusal-das",fullName:"Kusal Das",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSBDeQAO/Profile_Picture_1623411145568",biography:"Kusal K. Das is a Distinguished Chair Professor of Physiology, Shri B. M. Patil Medical College and Director, Centre for Advanced Medical Research (CAMR), BLDE (Deemed to be University), Vijayapur, Karnataka, India. Dr. Das did his M.S. and Ph.D. in Human Physiology from the University of Calcutta, Kolkata. His area of research is focused on understanding of molecular mechanisms of heavy metal activated low oxygen sensing pathways in vascular pathophysiology. He has invented a new method of estimation of serum vitamin E. His expertise in critical experimental protocols on vascular functions in experimental animals was well documented by his quality of publications. He was a Visiting Professor of Medicine at University of Leeds, United Kingdom (2014-2016) and Tulane University, New Orleans, USA (2017). For his immense contribution in medical research Ministry of Science and Technology, Government of India conferred him 'G.P. Chatterjee Memorial Research Prize-2019” and he is also the recipient of 'Dr.Raja Ramanna State Scientist Award 2015” by Government of Karnataka. He is a Fellow of the Royal Society of Biology (FRSB), London and Honorary Fellow of Karnataka Science and Technology Academy, Department of Science and Technology, Government of Karnataka.",institutionString:"BLDE (Deemed to be University), India",institution:null},{id:"243660",title:"Dr.",name:"Mallanagouda Shivanagouda",middleName:null,surname:"Biradar",slug:"mallanagouda-shivanagouda-biradar",fullName:"Mallanagouda Shivanagouda Biradar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/243660/images/system/243660.jpeg",biography:"M. S. Biradar is Vice Chancellor and Professor of Medicine of\nBLDE (Deemed to be University), Vijayapura, Karnataka, India.\nHe obtained his MD with a gold medal in General Medicine and\nhas devoted himself to medical teaching, research, and administrations. He has also immensely contributed to medical research\non vascular medicine, which is reflected by his numerous publications including books and book chapters. Professor Biradar was\nalso Visiting Professor at Tulane University School of Medicine, New Orleans, USA.",institutionString:"BLDE (Deemed to be University)",institution:{name:"BLDE University",country:{name:"India"}}},{id:"289796",title:"Dr.",name:"Swastika",middleName:null,surname:"Das",slug:"swastika-das",fullName:"Swastika Das",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/289796/images/system/289796.jpeg",biography:"Swastika N. Das is Professor of Chemistry at the V. P. Dr. P. G.\nHalakatti College of Engineering and Technology, BLDE (Deemed\nto be University), Vijayapura, Karnataka, India. She obtained an\nMSc, MPhil, and PhD in Chemistry from Sambalpur University,\nOdisha, India. Her areas of research interest are medicinal chemistry, chemical kinetics, and free radical chemistry. She is a member\nof the investigators who invented a new modified method of estimation of serum vitamin E. She has authored numerous publications including book\nchapters and is a mentor of doctoral curriculum at her university.",institutionString:"BLDEA’s V.P.Dr.P.G.Halakatti College of Engineering & Technology",institution:{name:"BLDE University",country:{name:"India"}}},{id:"248459",title:"Dr.",name:"Akikazu",middleName:null,surname:"Takada",slug:"akikazu-takada",fullName:"Akikazu Takada",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/248459/images/system/248459.png",biography:"Akikazu Takada was born in Japan, 1935. After graduation from\nKeio University School of Medicine and finishing his post-graduate studies, he worked at Roswell Park Memorial Institute NY,\nUSA. He then took a professorship at Hamamatsu University\nSchool of Medicine. In thrombosis studies, he found the SK\npotentiator that enhances plasminogen activation by streptokinase. He is very much interested in simultaneous measurements\nof fatty acids, amino acids, and tryptophan degradation products. By using fatty\nacid analyses, he indicated that plasma levels of trans-fatty acids of old men were\nfar higher in the US than Japanese men. . He also showed that eicosapentaenoic acid\n(EPA) and docosahexaenoic acid (DHA) levels are higher, and arachidonic acid\nlevels are lower in Japanese than US people. By using simultaneous LC/MS analyses\nof plasma levels of tryptophan metabolites, he recently found that plasma levels of\nserotonin, kynurenine, or 5-HIAA were higher in patients of mono- and bipolar\ndepression, which are significantly different from observations reported before. In\nview of recent reports that plasma tryptophan metabolites are mainly produced by\nmicrobiota. He is now working on the relationships between microbiota and depression or autism.",institutionString:"Hamamatsu University School of Medicine",institution:{name:"Hamamatsu University School of Medicine",country:{name:"Japan"}}},{id:"137240",title:"Prof.",name:"Mohammed",middleName:null,surname:"Khalid",slug:"mohammed-khalid",fullName:"Mohammed Khalid",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/137240/images/system/137240.png",biography:"Mohammed Khalid received his B.S. degree in chemistry in 2000 and Ph.D. degree in physical chemistry in 2007 from the University of Khartoum, Sudan. He moved to School of Chemistry, Faculty of Science, University of Sydney, Australia in 2009 and joined Dr. Ron Clarke as a postdoctoral fellow where he worked on the interaction of ATP with the phosphoenzyme of the Na+/K+-ATPase and dual mechanisms of allosteric acceleration of the Na+/K+-ATPase by ATP; then he went back to Department of Chemistry, University of Khartoum as an assistant professor, and in 2014 he was promoted as an associate professor. In 2011, he joined the staff of Department of Chemistry at Taif University, Saudi Arabia, where he is currently an assistant professor. His research interests include the following: P-Type ATPase enzyme kinetics and mechanisms, kinetics and mechanisms of redox reactions, autocatalytic reactions, computational enzyme kinetics, allosteric acceleration of P-type ATPases by ATP, exploring of allosteric sites of ATPases, and interaction of ATP with ATPases located in cell membranes.",institutionString:"Taif University",institution:{name:"Taif University",country:{name:"Saudi Arabia"}}},{id:"63810",title:"Prof.",name:"Jorge",middleName:null,surname:"Morales-Montor",slug:"jorge-morales-montor",fullName:"Jorge Morales-Montor",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/63810/images/system/63810.png",biography:"Dr. Jorge Morales-Montor was recognized with the Lola and Igo Flisser PUIS Award for best graduate thesis at the national level in the field of parasitology. He received a fellowship from the Fogarty Foundation to perform postdoctoral research stay at the University of Georgia. He has 153 journal articles to his credit. He has also edited several books and published more than fifty-five book chapters. He is a member of the Mexican Academy of Sciences, Latin American Academy of Sciences, and the National Academy of Medicine. He has received more than thirty-five awards and has supervised numerous bachelor’s, master’s, and Ph.D. students. Dr. Morales-Montor is the past president of the Mexican Society of Parasitology.",institutionString:"National Autonomous University of Mexico",institution:{name:"National Autonomous University of Mexico",country:{name:"Mexico"}}},{id:"217215",title:"Dr.",name:"Palash",middleName:null,surname:"Mandal",slug:"palash-mandal",fullName:"Palash Mandal",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/217215/images/system/217215.jpeg",biography:null,institutionString:"Charusat University",institution:null},{id:"49739",title:"Dr.",name:"Leszek",middleName:null,surname:"Szablewski",slug:"leszek-szablewski",fullName:"Leszek Szablewski",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/49739/images/system/49739.jpg",biography:"Leszek Szablewski is a professor of medical sciences. He received his M.S. in the Faculty of Biology from the University of Warsaw and his PhD degree from the Institute of Experimental Biology Polish Academy of Sciences. He habilitated in the Medical University of Warsaw, and he obtained his degree of Professor from the President of Poland. Professor Szablewski is the Head of Chair and Department of General Biology and Parasitology, Medical University of Warsaw. Professor Szablewski has published over 80 peer-reviewed papers in journals such as Journal of Alzheimer’s Disease, Biochim. Biophys. Acta Reviews of Cancer, Biol. Chem., J. Biomed. Sci., and Diabetes/Metabol. Res. Rev, Endocrine. He is the author of two books and four book chapters. He has edited four books, written 15 scripts for students, is the ad hoc reviewer of over 30 peer-reviewed journals, and editorial member of peer-reviewed journals. Prof. Szablewski’s research focuses on cell physiology, genetics, and pathophysiology. He works on the damage caused by lack of glucose homeostasis and changes in the expression and/or function of glucose transporters due to various diseases. He has given lectures, seminars, and exercises for students at the Medical University.",institutionString:"Medical University of Warsaw",institution:{name:"Medical University of Warsaw",country:{name:"Poland"}}},{id:"173123",title:"Dr.",name:"Maitham",middleName:null,surname:"Khajah",slug:"maitham-khajah",fullName:"Maitham Khajah",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/173123/images/system/173123.jpeg",biography:"Dr. Maitham A. Khajah received his degree in Pharmacy from Faculty of Pharmacy, Kuwait University, in 2003 and obtained his PhD degree in December 2009 from the University of Calgary, Canada (Gastrointestinal Science and Immunology). Since January 2010 he has been assistant professor in Kuwait University, Faculty of Pharmacy, Department of Pharmacology and Therapeutics. His research interest are molecular targets for the treatment of inflammatory bowel disease (IBD) and the mechanisms responsible for immune cell chemotaxis. He cosupervised many students for the MSc Molecular Biology Program, College of Graduate Studies, Kuwait University. Ever since joining Kuwait University in 2010, he got various grants as PI and Co-I. He was awarded the Best Young Researcher Award by Kuwait University, Research Sector, for the Year 2013–2014. He was a member in the organizing committee for three conferences organized by Kuwait University, Faculty of Pharmacy, as cochair and a member in the scientific committee (the 3rd, 4th, and 5th Kuwait International Pharmacy Conference).",institutionString:"Kuwait University",institution:{name:"Kuwait University",country:{name:"Kuwait"}}},{id:"195136",title:"Dr.",name:"Aya",middleName:null,surname:"Adel",slug:"aya-adel",fullName:"Aya Adel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/195136/images/system/195136.jpg",biography:"Dr. Adel works as an Assistant Lecturer in the unit of Phoniatrics, Department of Otolaryngology, Ain Shams University in Cairo, Egypt. Dr. Adel is especially interested in joint attention and its impairment in autism spectrum disorder",institutionString:"Ain Shams University",institution:{name:"Ain Shams University",country:{name:"Egypt"}}},{id:"94911",title:"Dr.",name:"Boulenouar",middleName:null,surname:"Mesraoua",slug:"boulenouar-mesraoua",fullName:"Boulenouar Mesraoua",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/94911/images/system/94911.png",biography:"Dr Boulenouar Mesraoua is the Associate Professor of Clinical Neurology at Weill Cornell Medical College-Qatar and a Consultant Neurologist at Hamad Medical Corporation at the Neuroscience Department; He graduated as a Medical Doctor from the University of Oran, Algeria; he then moved to Belgium, the City of Liege, for a Residency in Internal Medicine and Neurology at Liege University; after getting the Belgian Board of Neurology (with high marks), he went to the National Hospital for Nervous Diseases, Queen Square, London, United Kingdom for a fellowship in Clinical Neurophysiology, under Pr Willison ; Dr Mesraoua had also further training in Epilepsy and Continuous EEG Monitoring for two years (from 2001-2003) in the Neurophysiology department of Zurich University, Switzerland, under late Pr Hans Gregor Wieser ,an internationally known epileptologist expert. \n\nDr B. Mesraoua is the Director of the Neurology Fellowship Program at the Neurology Section and an active member of the newly created Comprehensive Epilepsy Program at Hamad General Hospital, Doha, Qatar; he is also Assistant Director of the Residency Program at the Qatar Medical School. \nDr B. Mesraoua's main interests are Epilepsy, Multiple Sclerosis, and Clinical Neurology; He is the Chairman and the Organizer of the well known Qatar Epilepsy Symposium, he is running yearly for the past 14 years and which is considered a landmark in the Gulf region; He has also started last year , together with other epileptologists from Qatar, the region and elsewhere, a yearly International Epilepsy School Course, which was attended by many neurologists from the Area.\n\nInternationally, Dr Mesraoua is an active and elected member of the Commission on Eastern Mediterranean Region (EMR ) , a regional branch of the International League Against Epilepsy (ILAE), where he represents the Middle East and North Africa(MENA ) and where he holds the position of chief of the Epilepsy Epidemiology Section; Dr Mesraoua is a member of the American Academy of Neurology, the Europeen Academy of Neurology and the American Epilepsy Society.\n\nDr Mesraoua's main objectives are to encourage frequent gathering of the epileptologists/neurologists from the MENA region and the rest of the world, promote Epilepsy Teaching in the MENA Region, and encourage multicenter studies involving neurologists and epileptologists in the MENA region, particularly epilepsy epidemiological studies. \n\nDr. Mesraoua is the recipient of two research Grants, as the Lead Principal Investigator (750.000 USD and 250.000 USD) from the Qatar National Research Fund (QNRF) and the Hamad Hospital Internal Research Grant (IRGC), on the following topics : “Continuous EEG Monitoring in the ICU “ and on “Alpha-lactoalbumin , proof of concept in the treatment of epilepsy” .Dr Mesraoua is a reviewer for the journal \"seizures\" (Europeen Epilepsy Journal ) as well as dove journals ; Dr Mesraoua is the author and co-author of many peer reviewed publications and four book chapters in the field of Epilepsy and Clinical Neurology",institutionString:"Weill Cornell Medical College in Qatar",institution:{name:"Weill Cornell Medical College in Qatar",country:{name:"Qatar"}}},{id:"282429",title:"Prof.",name:"Covanis",middleName:null,surname:"Athanasios",slug:"covanis-athanasios",fullName:"Covanis Athanasios",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/282429/images/system/282429.jpg",biography:null,institutionString:"Neurology-Neurophysiology Department of the Children Hospital Agia Sophia",institution:null},{id:"190980",title:"Prof.",name:"Marwa",middleName:null,surname:"Mahmoud Saleh",slug:"marwa-mahmoud-saleh",fullName:"Marwa Mahmoud Saleh",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/190980/images/system/190980.jpg",biography:"Professor Marwa Mahmoud Saleh is a doctor of medicine and currently works in the unit of Phoniatrics, Department of Otolaryngology, Ain Shams University in Cairo, Egypt. She got her doctoral degree in 1991 and her doctoral thesis was accomplished in the University of Iowa, United States. Her publications covered a multitude of topics as videokymography, cochlear implants, stuttering, and dysphagia. She has lectured Egyptian phonology for many years. Her recent research interest is joint attention in autism.",institutionString:"Ain Shams University",institution:{name:"Ain Shams University",country:{name:"Egypt"}}},{id:"259190",title:"Dr.",name:"Syed Ali Raza",middleName:null,surname:"Naqvi",slug:"syed-ali-raza-naqvi",fullName:"Syed Ali Raza Naqvi",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259190/images/system/259190.png",biography:"Dr. Naqvi is a radioanalytical chemist and is working as an associate professor of analytical chemistry in the Department of Chemistry, Government College University, Faisalabad, Pakistan. Advance separation techniques, nuclear analytical techniques and radiopharmaceutical analysis are the main courses that he is teaching to graduate and post-graduate students. In the research area, he is focusing on the development of organic- and biomolecule-based radiopharmaceuticals for diagnosis and therapy of infectious and cancerous diseases. Under the supervision of Dr. Naqvi, three students have completed their Ph.D. degrees and 41 students have completed their MS degrees. He has completed three research projects and is currently working on 2 projects entitled “Radiolabeling of fluoroquinolone derivatives for the diagnosis of deep-seated bacterial infections” and “Radiolabeled minigastrin peptides for diagnosis and therapy of NETs”. He has published about 100 research articles in international reputed journals and 7 book chapters. Pakistan Institute of Nuclear Science & Technology (PINSTECH) Islamabad, Punjab Institute of Nuclear Medicine (PINM), Faisalabad and Institute of Nuclear Medicine and Radiology (INOR) Abbottabad are the main collaborating institutes.",institutionString:"Government College University",institution:{name:"Government College University, Faisalabad",country:{name:"Pakistan"}}},{id:"58390",title:"Dr.",name:"Gyula",middleName:null,surname:"Mozsik",slug:"gyula-mozsik",fullName:"Gyula Mozsik",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/58390/images/system/58390.png",biography:"Gyula Mózsik MD, Ph.D., ScD (med), is an emeritus professor of Medicine at the First Department of Medicine, Univesity of Pécs, Hungary. He was head of this department from 1993 to 2003. His specializations are medicine, gastroenterology, clinical pharmacology, clinical nutrition, and dietetics. His research fields are biochemical pharmacological examinations in the human gastrointestinal (GI) mucosa, mechanisms of retinoids, drugs, capsaicin-sensitive afferent nerves, and innovative pharmacological, pharmaceutical, and nutritional (dietary) research in humans. He has published about 360 peer-reviewed papers, 197 book chapters, 692 abstracts, 19 monographs, and has edited 37 books. He has given about 1120 regular and review lectures. He has organized thirty-eight national and international congresses and symposia. He is the founder of the International Conference on Ulcer Research (ICUR); International Union of Pharmacology, Gastrointestinal Section (IUPHAR-GI); Brain-Gut Society symposiums, and gastrointestinal cytoprotective symposiums. He received the Andre Robert Award from IUPHAR-GI in 2014. Fifteen of his students have been appointed as full professors in Egypt, Cuba, and Hungary.",institutionString:"University of Pécs",institution:{name:"University of Pecs",country:{name:"Hungary"}}},{id:"277367",title:"M.Sc.",name:"Daniel",middleName:"Martin",surname:"Márquez López",slug:"daniel-marquez-lopez",fullName:"Daniel Márquez López",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/277367/images/7909_n.jpg",biography:"Msc Daniel Martin Márquez López has a bachelor degree in Industrial Chemical Engineering, a Master of science degree in the same área and he is a PhD candidate for the Instituto Politécnico Nacional. His Works are realted to the Green chemistry field, biolubricants, biodiesel, transesterification reactions for biodiesel production and the manipulation of oils for therapeutic purposes.",institutionString:null,institution:{name:"Instituto Politécnico Nacional",country:{name:"Mexico"}}},{id:"196544",title:"Prof.",name:"Angel",middleName:null,surname:"Catala",slug:"angel-catala",fullName:"Angel Catala",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/196544/images/system/196544.jpg",biography:"Angel Catalá studied chemistry at Universidad Nacional de La Plata, Argentina, where he received a Ph.D. in Chemistry (Biological Branch) in 1965. From 1964 to 1974, he worked as an Assistant in Biochemistry at the School of Medicine at the same university. From 1974 to 1976, he was a fellow of the National Institutes of Health (NIH) at the University of Connecticut, Health Center, USA. From 1985 to 2004, he served as a Full Professor of Biochemistry at the Universidad Nacional de La Plata. He is a member of the National Research Council (CONICET), Argentina, and the Argentine Society for Biochemistry and Molecular Biology (SAIB). His laboratory has been interested for many years in the lipid peroxidation of biological membranes from various tissues and different species. Dr. Catalá has directed twelve doctoral theses, published more than 100 papers in peer-reviewed journals, several chapters in books, and edited twelve books. He received awards at the 40th International Conference Biochemistry of Lipids 1999 in Dijon, France. He is the winner of the Bimbo Pan-American Nutrition, Food Science and Technology Award 2006 and 2012, South America, Human Nutrition, Professional Category. In 2006, he won the Bernardo Houssay award in pharmacology, in recognition of his meritorious works of research. Dr. Catalá belongs to the editorial board of several journals including Journal of Lipids; International Review of Biophysical Chemistry; Frontiers in Membrane Physiology and Biophysics; World Journal of Experimental Medicine and Biochemistry Research International; World Journal of Biological Chemistry, Diabetes, and the Pancreas; International Journal of Chronic Diseases & Therapy; and International Journal of Nutrition. He is the co-editor of The Open Biology Journal and associate editor for Oxidative Medicine and Cellular Longevity.",institutionString:"Universidad Nacional de La Plata",institution:{name:"National University of La Plata",country:{name:"Argentina"}}},{id:"186585",title:"Dr.",name:"Francisco Javier",middleName:null,surname:"Martin-Romero",slug:"francisco-javier-martin-romero",fullName:"Francisco Javier Martin-Romero",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSB3HQAW/Profile_Picture_1631258137641",biography:"Francisco Javier Martín-Romero (Javier) is a Professor of Biochemistry and Molecular Biology at the University of Extremadura, Spain. He is also a group leader at the Biomarkers Institute of Molecular Pathology. Javier received his Ph.D. in 1998 in Biochemistry and Biophysics. At the National Cancer Institute (National Institute of Health, Bethesda, MD) he worked as a research associate on the molecular biology of selenium and its role in health and disease. After postdoctoral collaborations with Carlos Gutierrez-Merino (University of Extremadura, Spain) and Dario Alessi (University of Dundee, UK), he established his own laboratory in 2008. The interest of Javier's lab is the study of cell signaling with a special focus on Ca2+ signaling, and how Ca2+ transport modulates the cytoskeleton, migration, differentiation, cell death, etc. He is especially interested in the study of Ca2+ channels, and the role of STIM1 in the initiation of pathological events.",institutionString:null,institution:{name:"University of Extremadura",country:{name:"Spain"}}},{id:"217323",title:"Prof.",name:"Guang-Jer",middleName:null,surname:"Wu",slug:"guang-jer-wu",fullName:"Guang-Jer Wu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/217323/images/8027_n.jpg",biography:null,institutionString:null,institution:null},{id:"148546",title:"Dr.",name:"Norma Francenia",middleName:null,surname:"Santos-Sánchez",slug:"norma-francenia-santos-sanchez",fullName:"Norma Francenia Santos-Sánchez",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/148546/images/4640_n.jpg",biography:null,institutionString:null,institution:null},{id:"272889",title:"Dr.",name:"Narendra",middleName:null,surname:"Maddu",slug:"narendra-maddu",fullName:"Narendra Maddu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/272889/images/10758_n.jpg",biography:null,institutionString:null,institution:null},{id:"242491",title:"Prof.",name:"Angelica",middleName:null,surname:"Rueda",slug:"angelica-rueda",fullName:"Angelica Rueda",position:"Investigador Cinvestav 3B",profilePictureURL:"https://mts.intechopen.com/storage/users/242491/images/6765_n.jpg",biography:null,institutionString:null,institution:null},{id:"88631",title:"Dr.",name:"Ivan",middleName:null,surname:"Petyaev",slug:"ivan-petyaev",fullName:"Ivan Petyaev",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Lycotec (United Kingdom)",country:{name:"United Kingdom"}}},{id:"423869",title:"Ms.",name:"Smita",middleName:null,surname:"Rai",slug:"smita-rai",fullName:"Smita Rai",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Integral University",country:{name:"India"}}},{id:"424024",title:"Prof.",name:"Swati",middleName:null,surname:"Sharma",slug:"swati-sharma",fullName:"Swati Sharma",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Integral University",country:{name:"India"}}},{id:"439112",title:"MSc.",name:"Touseef",middleName:null,surname:"Fatima",slug:"touseef-fatima",fullName:"Touseef Fatima",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Integral University",country:{name:"India"}}},{id:"424836",title:"Dr.",name:"Orsolya",middleName:null,surname:"Borsai",slug:"orsolya-borsai",fullName:"Orsolya Borsai",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca",country:{name:"Romania"}}},{id:"422262",title:"Ph.D.",name:"Paola Andrea",middleName:null,surname:"Palmeros-Suárez",slug:"paola-andrea-palmeros-suarez",fullName:"Paola Andrea Palmeros-Suárez",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Guadalajara",country:{name:"Mexico"}}}]}},subseries:{item:{id:"12",type:"subseries",title:"Human Physiology",keywords:"Anatomy, Cells, Organs, Systems, Homeostasis, Functions",scope:"Human physiology is the scientific exploration of the various functions (physical, biochemical, and mechanical properties) of humans, their organs, and their constituent cells. 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