\r\n\tThe aim of this book is to provide the reader with a comprehensive state-of-the-art in artificial neural networks, collecting many of the core concepts and cutting-edge application behind neural networks and deep learning.
",isbn:"978-1-83962-375-2",printIsbn:"978-1-83962-374-5",pdfIsbn:"978-1-83962-376-9",doi:null,price:0,priceEur:0,priceUsd:0,slug:null,numberOfPages:0,isOpenForSubmission:!1,hash:"5cc6cd7972551be6cfc4d3c87bf8fb5c",bookSignature:"Dr. Pier Luigi Mazzeo and Dr. Paolo Spagnolo",publishedDate:null,coverURL:"https://cdn.intechopen.com/books/images_new/10390.jpg",keywords:"Recurrent, Recursive Nets, Face Recognition, Crowd Analysis, Different Applications, Object Detection, Classification, Visual Tracking, Speech Recognition, Grams, Reinforcement Learning, 3-D Map",numberOfDownloads:75,numberOfWosCitations:0,numberOfCrossrefCitations:0,numberOfDimensionsCitations:0,numberOfTotalCitations:0,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"September 25th 2020",dateEndSecondStepPublish:"October 23rd 2020",dateEndThirdStepPublish:"December 22nd 2020",dateEndFourthStepPublish:"March 12th 2021",dateEndFifthStepPublish:"May 11th 2021",remainingDaysToSecondStep:"4 months",secondStepPassed:!0,currentStepOfPublishingProcess:4,editedByType:null,kuFlag:!1,biosketch:"Author and co-author of more than 80 works in national and international journals, conference proceedings, and book chapters, with Ph.D. in Computer Science Engineering.",coeditorOneBiosketch:"Dr. Spagnolo received the engineering degree in computer science from the University of Lecce, Italy. Since 2002 he has been with the Italian National Research Council. His work includes more than 80 publications on AI.",coeditorTwoBiosketch:null,coeditorThreeBiosketch:null,coeditorFourBiosketch:null,coeditorFiveBiosketch:null,editors:[{id:"17191",title:"Dr.",name:"Pier Luigi",middleName:null,surname:"Mazzeo",slug:"pier-luigi-mazzeo",fullName:"Pier Luigi Mazzeo",profilePictureURL:"https://mts.intechopen.com/storage/users/17191/images/system/17191.jpeg",biography:"Pier Luigi Mazzeo received the engineering degree in computer science from the University of Lecce, Lecce, Italy, in 2001. \nSince 2015 he has been with Institute of Applied Sciences and Intelligent Systems of the Italian National Research Council, Lecce, Italy. The most relevant topics, in which he is currently involved, include algorithms for video object tracking , face detection and recognition, facial expression recognition, deep neural network (CNN) and machine learning.\nHe has taken part in several national and international projects and he acts as a reviewer for several international journals and for some book publishers. He has been regularly invited to take part in the Scientific Committees of national and international conferences. \nDr. Mazzeo is author and co-author of more then 80 works in national and international journals, conference proceedings and book chapters.",institutionString:"Institute of Applied Sciences and Intelligent Systems (CNR)",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"1",totalChapterViews:"0",totalEditedBooks:"1",institution:{name:"Institute of Applied Science and Intelligent Systems",institutionURL:null,country:{name:"Italy"}}}],coeditorOne:{id:"20192",title:"Dr.",name:"Paolo",middleName:null,surname:"Spagnolo",slug:"paolo-spagnolo",fullName:"Paolo Spagnolo",profilePictureURL:"https://mts.intechopen.com/storage/users/20192/images/system/20192.jpg",biography:"Paolo Spagnolo received the engineering degree in computer science from the University of Lecce, Lecce, Italy, in 2002.\nSince then he has been with the Italian National Research Council.\nHe has been working on several research topics regarding Artificial Intelligence and Computer Vision studying techniques and methodologies for multidimensional digital signal processing; linear and non-linear signal characterization; signal features extraction; supervised and unsupervised classification of signals; deep neural network (CNN).\nDr. Spagnolo is an author of over 80 papers on Artificial Intelligence. He also acts as a reviewer for several international journals.\nHe has also participated in a number of international projects in the area of image and video analysis and has been regularly invited to take part in the Scientific Committees of national and international conferences.",institutionString:"Institute of Applied Sciences and Intelligent Systems (CNR)",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"1",totalChapterViews:"0",totalEditedBooks:"0",institution:{name:"Institute of Applied Science and Intelligent Systems",institutionURL:null,country:{name:"Italy"}}},coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"9",title:"Computer and Information Science",slug:"computer-and-information-science"}],chapters:[{id:"75265",title:"Deep Learning for Subtyping and Prediction of Diseases: Long-Short Term Memory",slug:"deep-learning-for-subtyping-and-prediction-of-diseases-long-short-term-memory",totalDownloads:32,totalCrossrefCites:0,authors:[{id:"179217",title:"Prof.",name:"Hayrettin",surname:"Okut",slug:"hayrettin-okut",fullName:"Hayrettin Okut"}]},{id:"75193",title:"The Digital Twin of an Organization by Utilizing Reinforcing Deep Learning",slug:"the-digital-twin-of-an-organization-by-utilizing-reinforcing-deep-learning",totalDownloads:32,totalCrossrefCites:0,authors:[null]},{id:"75329",title:"Risk Assessment and Automated Anomaly Detection Using a Deep Learning Architecture",slug:"risk-assessment-and-automated-anomaly-detection-using-a-deep-learning-architecture",totalDownloads:7,totalCrossrefCites:0,authors:[null]},{id:"75342",title:"Application of Deep Learning Methods for Detection and Tracking of Players",slug:"application-of-deep-learning-methods-for-detection-and-tracking-of-players",totalDownloads:13,totalCrossrefCites:0,authors:[null]}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},personalPublishingAssistant:{id:"297737",firstName:"Mateo",lastName:"Pulko",middleName:null,title:"Mr.",imageUrl:"https://mts.intechopen.com/storage/users/297737/images/8492_n.png",email:"mateo.p@intechopen.com",biography:"As an Author Service Manager my responsibilities include monitoring and facilitating all publishing activities for authors and editors. From chapter submission and review, to approval and revision, copyediting and design, until final publication, I work closely with authors and editors to ensure a simple and easy publishing process. I maintain constant and effective communication with authors, editors and reviewers, which allows for a level of personal support that enables contributors to fully commit and concentrate on the chapters they are writing, editing, or reviewing. I assist authors in the preparation of their full chapter submissions and track important deadlines and ensure they are met. I help to coordinate internal processes such as linguistic review, and monitor the technical aspects of the process. As an ASM I am also involved in the acquisition of editors. Whether that be identifying an exceptional author and proposing an editorship collaboration, or contacting researchers who would like the opportunity to work with IntechOpen, I establish and help manage author and editor acquisition and contact."}},relatedBooks:[{type:"book",id:"8725",title:"Visual Object Tracking with Deep Neural Networks",subtitle:null,isOpenForSubmission:!1,hash:"e0ba384ed4b4e61f042d5147c97ab168",slug:"visual-object-tracking-with-deep-neural-networks",bookSignature:"Pier Luigi Mazzeo, Srinivasan Ramakrishnan and Paolo Spagnolo",coverURL:"https://cdn.intechopen.com/books/images_new/8725.jpg",editedByType:"Edited by",editors:[{id:"17191",title:"Dr.",name:"Pier Luigi",surname:"Mazzeo",slug:"pier-luigi-mazzeo",fullName:"Pier Luigi Mazzeo"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1591",title:"Infrared Spectroscopy",subtitle:"Materials Science, Engineering and Technology",isOpenForSubmission:!1,hash:"99b4b7b71a8caeb693ed762b40b017f4",slug:"infrared-spectroscopy-materials-science-engineering-and-technology",bookSignature:"Theophile Theophanides",coverURL:"https://cdn.intechopen.com/books/images_new/1591.jpg",editedByType:"Edited by",editors:[{id:"37194",title:"Dr.",name:"Theophanides",surname:"Theophile",slug:"theophanides-theophile",fullName:"Theophanides Theophile"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3092",title:"Anopheles mosquitoes",subtitle:"New insights into malaria vectors",isOpenForSubmission:!1,hash:"c9e622485316d5e296288bf24d2b0d64",slug:"anopheles-mosquitoes-new-insights-into-malaria-vectors",bookSignature:"Sylvie Manguin",coverURL:"https://cdn.intechopen.com/books/images_new/3092.jpg",editedByType:"Edited by",editors:[{id:"50017",title:"Prof.",name:"Sylvie",surname:"Manguin",slug:"sylvie-manguin",fullName:"Sylvie Manguin"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3161",title:"Frontiers in Guided Wave Optics and Optoelectronics",subtitle:null,isOpenForSubmission:!1,hash:"deb44e9c99f82bbce1083abea743146c",slug:"frontiers-in-guided-wave-optics-and-optoelectronics",bookSignature:"Bishnu Pal",coverURL:"https://cdn.intechopen.com/books/images_new/3161.jpg",editedByType:"Edited by",editors:[{id:"4782",title:"Prof.",name:"Bishnu",surname:"Pal",slug:"bishnu-pal",fullName:"Bishnu Pal"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"72",title:"Ionic Liquids",subtitle:"Theory, Properties, New Approaches",isOpenForSubmission:!1,hash:"d94ffa3cfa10505e3b1d676d46fcd3f5",slug:"ionic-liquids-theory-properties-new-approaches",bookSignature:"Alexander Kokorin",coverURL:"https://cdn.intechopen.com/books/images_new/72.jpg",editedByType:"Edited by",editors:[{id:"19816",title:"Prof.",name:"Alexander",surname:"Kokorin",slug:"alexander-kokorin",fullName:"Alexander Kokorin"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1373",title:"Ionic Liquids",subtitle:"Applications and Perspectives",isOpenForSubmission:!1,hash:"5e9ae5ae9167cde4b344e499a792c41c",slug:"ionic-liquids-applications-and-perspectives",bookSignature:"Alexander Kokorin",coverURL:"https://cdn.intechopen.com/books/images_new/1373.jpg",editedByType:"Edited by",editors:[{id:"19816",title:"Prof.",name:"Alexander",surname:"Kokorin",slug:"alexander-kokorin",fullName:"Alexander Kokorin"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"57",title:"Physics and Applications of Graphene",subtitle:"Experiments",isOpenForSubmission:!1,hash:"0e6622a71cf4f02f45bfdd5691e1189a",slug:"physics-and-applications-of-graphene-experiments",bookSignature:"Sergey Mikhailov",coverURL:"https://cdn.intechopen.com/books/images_new/57.jpg",editedByType:"Edited by",editors:[{id:"16042",title:"Dr.",name:"Sergey",surname:"Mikhailov",slug:"sergey-mikhailov",fullName:"Sergey Mikhailov"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"371",title:"Abiotic Stress in Plants",subtitle:"Mechanisms and Adaptations",isOpenForSubmission:!1,hash:"588466f487e307619849d72389178a74",slug:"abiotic-stress-in-plants-mechanisms-and-adaptations",bookSignature:"Arun Shanker and B. Venkateswarlu",coverURL:"https://cdn.intechopen.com/books/images_new/371.jpg",editedByType:"Edited by",editors:[{id:"58592",title:"Dr.",name:"Arun",surname:"Shanker",slug:"arun-shanker",fullName:"Arun Shanker"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"878",title:"Phytochemicals",subtitle:"A Global Perspective of Their Role in Nutrition and Health",isOpenForSubmission:!1,hash:"ec77671f63975ef2d16192897deb6835",slug:"phytochemicals-a-global-perspective-of-their-role-in-nutrition-and-health",bookSignature:"Venketeshwer Rao",coverURL:"https://cdn.intechopen.com/books/images_new/878.jpg",editedByType:"Edited by",editors:[{id:"82663",title:"Dr.",name:"Venketeshwer",surname:"Rao",slug:"venketeshwer-rao",fullName:"Venketeshwer Rao"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"4816",title:"Face Recognition",subtitle:null,isOpenForSubmission:!1,hash:"146063b5359146b7718ea86bad47c8eb",slug:"face_recognition",bookSignature:"Kresimir Delac and Mislav Grgic",coverURL:"https://cdn.intechopen.com/books/images_new/4816.jpg",editedByType:"Edited by",editors:[{id:"528",title:"Dr.",name:"Kresimir",surname:"Delac",slug:"kresimir-delac",fullName:"Kresimir Delac"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},chapter:{item:{type:"chapter",id:"47460",title:"The Role of the Dialysate Flow Rate in Haemodialysis",doi:"10.5772/58878",slug:"the-role-of-the-dialysate-flow-rate-in-haemodialysis",body:'
1. Introduction
Modern dialysis devices such as the Fresenius FMC 5008 allow the relationship between the flow rates of blood QB and dialysate QD to be fixed at a set ratio (e.g. QD=1.2 QB oder QD=1.5 QB). The FMC-Genius®-Therapy System, which uses a double-sided peristaltic pump for both the patient\'s blood and the dialysis fluid (50…350 ml/min), even allows a ratio of QB=QD.
The relationship between the effectiveness of haemodialysis on the one hand, and the flows of blood and dialysate on the other, is guided by physical principles. These principles have been known for some time and have been widely discussed in the literature [1]. However, the fact that dialysis machines are completely automated makes it easy to neglect the underlying principles, so much so that knowledge of these may at times be lacking. There are also financial pressures that result in a desire to economise on water and dialysate concentrate, and a desire to work with as low a dialysate flow rate as possible.
The following sections will provide a brief summary of the theory behind the principles involved. In vitro and in vivo testing results from some of the more commonly available dialysers are used to provide a clearer picture of the theoretical principles involved. These measurements show that in spite of modern dialysis membranes and structural changes, it is not in fact possible to reduce the dialysate flow rate without also reducing the dialysis dose.
2. Theoretical principles
The connection between the dialyser\'s technical parameters and the flow rates involved (QB, QD in the counter current flow) is based on the following relationship [1]:
KOA=QB(1−QB/QD)ln[1−K/QD1−K/QB]aKOA=K(1−K/QB)bE1
\n\t\t\t
For QB=QD the following applies: KOA=K1−K/QB\n\t\t\t
where Ko is the "overall mass transfer coefficient“ and A is the dialyser membrane surface area.
In dialysis log sheets, the KoA-value is usually recorded for urea, thus allowing the calculation of urea-clearance in relation to blood and dialysate flow rates.
Figure 1.
Dependence of clearance K on the flow rates of blood QB and dialysate QD (KoA=1000 ml/min)
Fig. 1 shows how clearance rate K, derived from the KoA value for a low molecular substance (urea), changes in relation to blood flow rates, with the relationship demonstrated at different dialysate flow rates, and for a high-flux dialyser. At low dialysate flow rates, the dialysate compartment soon becomes saturated, leading to a large reduction in the concentration gradient. This in turn means that an increase in blood flow will no longer produce a substantial improvement in the rate of clearance. It is only when the dialysate flow rate is high enough for the substance in question to be removed quickly from the dialysate chamber that a higher blood flow rate can produce substantial improvements in the rate of clearance. This is effectively only ever the case when the dialysate flow rate QD is at least 1.5…2.0 times as high as the blood flow rate, QB.
This theoretical relationship requires the KoA value to be constant for all dialysate and blood flow rates. This does of course not apply in practice in cases where the total surface area of the dialyser\'s fibre bundle is not completely bathed in dialysate. This may happen when low dialysate flow rates lead to preferential channels being formed (please also refer to Sections 3 and 4). In the presence of relatively low dialysate flow rates, therefore, clearance values which may seem possible in theory are in fact unachievable in practice.
It must be emphasised, however, that these observations only apply to transport by diffusion, the most important transport mechanism for low molecular weight substances such as urea, creatinine and phosphate. As far as larger molecules are concerned, it is convective solute transport that becomes increasingly important as the molecular weight of the solute increases. With regard to the manner in which the overall clearance KT depends on both of these mechanisms, only an incomplete explanation can be provided. Werynski\'s equation [2] offers a reasonable approach:
As the value for clearance by diffusion, Kdiff in relation to blood flow rate, QB, decreases, the transmittance coefficient approaches the sieving coefficient, and the overall clearance KT is effectively determined by the ultrafiltration rate QF. It follows that the dialysate flow rate QD has less significance with regard to larger molecules than it does with regard to smaller ones.
3. Structural changes to allow optimisation of the dialysate compartment
Fig. 2 shows an enhanced ultrasound image depicting an unfortunate case of channelling observed in a test dialyser during the inflow of dialysate.
Figure 2.
Enhanced ultrasound image of inflowing dialysate at QD=500 ml/min (Dialyser Altair 12G, US-machine Logic 7, GE Medical Systems, contrast agent: Optison®)
In order to avoid, or at least reduce, this channelling phenomenon, different structural alterations are commonly applied:
Flat sheet arrangement of hollow fibres
Wave-shaped hollow fibres (Moiré structure)
Spacer yarns
Pinnacle structure in the dialysate inflow and outflow areas.
Although a number of manufacturers at one point utilised flat-plate arrangements of interweaved hollow fibres in their dialysers (e.g. HFD 1.0 by MLW), this method has since been abandoned-probably due to cost reasons. Almost all manufacturers prefer the Moiré structure of fibres in order to obtain adequate spacing. In some instances-and sometimes in addition to the Moiré structure-spacing filaments (spacer yarns) are added (e.g. Asahi PAN650SF, MTP VitaPES). Although these measures ensure improved dialysate flow distribution within the cross-sectional area of the dialyser, in vitro testing using CT imaging has revealed that some preferential channelling through peripheral areas of the dialysate compartment remains [3, 4, 5]. With its FX series, Fresenius Medical Care followed a different path. Via a pinnacle structure in the inflow and outflow tracts, the dialysate is forced into even distribution across the entire surface area [6]. In the early days, dialyser technology included a number of devices whose inlet and outlet headers were fitted diagonally to improve the distribution of dialysate across the fibre bundle (e.g. EMC TriEx). For reasons unknown, this very simple solution did not prevail.
4. In vitro analyses examining dialysate flow dependence of solute clearance
A dialysis machine (FMC 4008) was used to perform in vitro measurements of clearance rates in accordance with standard ISO 8637. A batch of 7.0 L stirred and thermostatically warmed dialysis liquid served as “blood” with dissolved urea and vitamin B12 as test substances. Measurements were carried out at different dialysate and blood flow rates, with each dialysate flow rate (QD=300, 500, 800 ml/min) being measured at blood flow rate settings of QB=100, 200, 300, 400 ml/min. These measurements were repeated for the 3 different types of dialysers.
\n\t\t
\n\t\t
\n\t\t
\n\t\t
\n\t\t
\n\t\t\t
\n\t\t\t\tDialyser\n\t\t\t
\n\t\t\t
\n\t\t\t\tMembrane\n\t\t\t
\n\t\t\t
\n\t\t\t\tManufacturer\n\t\t\t
\n\t\t\t
\n\t\t\t\tKoA urea [ml/min]\n\t\t\t
\n\t\t
\n\t\t
\n\t\t\t
FDY-150 GW
\n\t\t\t
PEPA®\n\t\t\t
\n\t\t\t
Nikkiso
\n\t\t\t
874
\n\t\t
\n\t\t
\n\t\t\t
FX 60
\n\t\t\t
Helixone®\n\t\t\t
\n\t\t\t
FMC
\n\t\t\t
967
\n\t\t
\n\t\t
\n\t\t\t
VitaPES 150HF
\n\t\t\t
Purema®\n\t\t\t
\n\t\t\t
MTP Pirna
\n\t\t\t
1167
\n\t\t
\n\t
Table 1.
List of dialysers used for in vitro testing
Clearance data were obtained for one small molecule (urea, relative molecular weight=60) and one larger molecule (vitamin B12, relative molecular weight=1357). KoA values were then calculated according to GI. 1a, b and compared with the values provided by the manufacturers.
Fig. 3 shows that the measured characteristics generally followed the theoretical model (refer to Fig. 1). However, the clearance rates calculated using the catalogue KOA values were not achieved at low dialysate flow rates. It was not until QD=800 ml/min that the values obtained managed to improve slightly on the ones provided. Similar curves were obtained for the other types of dialysers. The KoA values calculated from clearance, QB and QD were dependent upon both blood flow rate of blood and dialysate flow rate. In an ideal scenario, this kind of relationship should not exist. The overall mass transfer coefficient, Ko, is a physical characteristic of the fibre bundle and does not vary with the flow rates that might exist on the blood-side or the dialysate-side. Different KoA values in the presence of different flow rates can be easily explained provided if the effective surface area A, which is involved in solute transport, fails to remain constant. Values that may be theoretically possible will of course not be achieved in situations where a low dialysate flow rate results in sections of the fibre bundle not being immersed in dialysate. Fig. 4 shows that the KoA value calculated for the dialyser FDY150GW depends upon the dialysate flow rate.
Figure 3.
Comparison of measured urea clearance values and urea clearance values derived from KoA data provided by the manufacturers.
Figure 4.
KoA values calculated based on clearance, QD and QB, using the dialyser FDY150GW as an example
In vitro KoA values [ml/min] for urea at different dialysate flow rates QD (mean values for different blood flow rates QB)
The dialyser FX60 showed the lowest degree of dialysate flow rate dependence of the KoA value. Although this was likely to be due to improved dialysate flow, the device still failed to achieve the manufacturer\'s catalogue value.
In summary, it has to be concluded that even modern high flux dialysers providing structural changes to optimise dialysate flow do not manage to negate the underlying relationship between the flow rates of blood and dialysate. Furthermore, full use of the fibre bundle\'s effective surface area A can only be guaranteed at high dialysate flow rates of around 800ml/min. Whilst this mirrors the results obtained by Leypolt [7], it contradicts the assumptions made by Golper and Ward, who concluded that structural improvements have made high dialysate flow rates unnecessary.
5. In vivo analyses examining the dialysate flow rate dependence of solute clearance
Naturally, in vitro investigations involving dialysers have to be treated with caution, with results not directly transferable to the clinical dialysis setting. Due to its viscosity and non-Newtonian flow properties, blood is a much more complex substance than an aqueous test solution. Also, unlike dialyser clearance rates, in vivo clearance rates depend upon physiological factors such as compartmentalisation of the blood and the uraemic toxins contained therein, fistula recirculation, cardiopulmonary recirculation, individual differences in haematocrit, as well as differences in protein and lipid concentrations. In spite of this, when looking at a sufficiently large number of patients and dialyses treatments, the basic principles discussed above should be mirrored in the clinical dialysis setting.
Figure 5.
(a): Dialysate flow rate dependence of the spKt/V value in dialyser FDY150GW (b): Dialysate flow rate dependence of the spKt/V value in dialyser FX60 (c): Dialysate flow rate dependence of the spKt/V value in dialyser VitaPES150HF
At a constant blood flow rate (QB=300 ml/min), a group of 6 patients received three treatments each at QD=300, 500 und 800 ml/min, with each set repeated for each of the 3 types of dialysers tested in vitro. In order to assess the effectiveness of treatment, the urea reduction ratio, single pool Kt/V (spKt/V) and equilibrated Kt/V (eqKt/V) were obtained (Daugirdas formula). In addition, OCM data were obtained for the dialysis machine FMC 5008 (Eff.Kt, Eff.Kt/V).
The figures show (as do the urea reduction ratios and eqKt/V results) that each step increase in dialysate flow can significantly improve the effectiveness of haemodialysis.
The interesting question for dialysis patients is of course the exact impact this may have on treatment time. A sample calculation using results from the FX60 dialyser will demonstrate this (see Table 3).
Time saved by using a dialysate flow rate of QD=500 ml/min or QD=800 ml/min instead of a dialysate flow rate of QD=300 ml/min
(Vcalc from OCM EffKt and measured Kt/V; tcalc=Kt/V(QD300)*V/K)
The same Kt/V value achieved at a dialysate flow rate QD=300 ml/min can be achieved at a dialysate flow rate of QD=500 ml/min, whilst treatment time can be reduced by between 13 and 25 minutes, depending on the individual patient\'s body mass and clearance. If a dialysate flow rate of QD=800 ml/min is used, treatment time will be reduced accordingly, namely by 26-36 min. Treatment time reduction of this order is certainly of interest to patients and should be able to outweigh the slight increase in costs incurred by higher dialysate flow rates. Naturally, if treatment time remains unchanged, a higher dialysate flow rate can also be used to improve the Kt/V value-as depicted in Fig. 5.
6. Summary
In vitro measurements obtained from a number of different modern high flux dialysers show that the characteristics "Clearance (QB, QD)“ manage to closely match theoretical scenarios of expected interdependence. However, in spite of a number of different structural improvements, the KoA value remains dependent upon the dialysate flow rate. A higher dialysate flow rate of around 800 ml/min ensures that the fibre bundle is bathed more evenly in dialysate, thus improving the effectiveness of dialysis.
In vivo investigations confirm that increases in dialysate flow rates are likely to produce significantly improved Kt/V values.
\n',keywords:null,chapterPDFUrl:"https://cdn.intechopen.com/pdfs/47460.pdf",chapterXML:"https://mts.intechopen.com/source/xml/47460.xml",downloadPdfUrl:"/chapter/pdf-download/47460",previewPdfUrl:"/chapter/pdf-preview/47460",totalDownloads:2644,totalViews:1458,totalCrossrefCites:0,totalDimensionsCites:1,hasAltmetrics:0,dateSubmitted:"June 4th 2014",dateReviewed:"July 16th 2014",datePrePublished:null,datePublished:"September 9th 2015",dateFinished:null,readingETA:"0",abstract:null,reviewType:"peer-reviewed",bibtexUrl:"/chapter/bibtex/47460",risUrl:"/chapter/ris/47460",book:{slug:"updates-in-hemodialysis"},signatures:"Peter Ahrenholz, Roland E. Winkler and Diego Zendeh-Zartochti",authors:[{id:"43902",title:"Dr.",name:"Roland",middleName:"E.",surname:"Winkler, M.B.A.",fullName:"Roland Winkler, M.B.A.",slug:"roland-winkler-m.b.a.",email:"roland.winkler@praxisverbund-rostock.de",position:"CEO",institution:null}],sections:[{id:"sec_1",title:"1. Introduction",level:"1"},{id:"sec_2",title:"2. Theoretical principles",level:"1"},{id:"sec_3",title:"3. Structural changes to allow optimisation of the dialysate compartment",level:"1"},{id:"sec_4",title:"4. In vitro analyses examining dialysate flow dependence of solute clearance",level:"1"},{id:"sec_5",title:"5. In vivo analyses examining the dialysate flow rate dependence of solute clearance",level:"1"},{id:"sec_6",title:"6. Summary",level:"1"}],chapterReferences:[{id:"B1",body:'Klein E, Autian J, Bower JD, Buffaloe G, Centella LJ, Colton CK, Darby TD, Farrell PC, Holland FF, Kennedy RS, et al.: Evaluation of hemodialyzers and dialysis membranes. Report of a study for the artificial kidney-chronic uremia program NIAMDD-1977. Artif Organs. 1978 Aug; 2(3):284-92.'},{id:"B2",body:'Weryński A: Evaluation of the impact of ultrafiltration on dialyzer clearance. Artif Organs. 1979 May;3(2):140-2.'},{id:"B3",body:'Ronco C, Bredolan A, Crepaldi C, Rodighiero M, Scabardi M: Blood and dialysate flow distributions in hollow-fiber hemodialyzers analyzed by computerized helical scanning technique. J Am Soc Nephrol 13: S53-S61, 2002'},{id:"B4",body:'Gastaldon F, Brendolan A, Crepaldi C, Frisone P, Zamboni S, d\'Intini V, Poulin S, Hector R, Granziero A, Martins K, Gellert R, Inguaggiato P, Ronco C: Effects of novel manufacturing technology on blood and dialysate flow distribution in a new low flux "alpha Polysulfone" hemodialyzer. Int J Artif Organs. 2003 Feb;26(2):105-112'},{id:"B5",body:'Kim JC, Kim JH, Kim HC, Kim KG, Lee JC, Kang E, Kim HC, Min BG, Ronco C: Three-dimensional dialysate flow analysis in a hollow-fiber dialyzer by perfusion computed tomography. Int J Artif Organs. 2008 Jun;31(6):553-60.'},{id:"B6",body:'Külz M, Nederlof B, Schneider H: In vitro and in vivo evaluation of a new dialyzer. Nephrol Dial Transplant (2002) 17: 1475-1479'},{id:"B7",body:'Leypoldt JK, Cheung AK, Agodoa LY, Daugirdas JT, Greene T, Keshaviah PR: Hemodialyzer mass transfer-area coefficients for urea increase at high dialysate flow rates. The Hemodialysis (HEMO) Study. Kidney Int. 1997 Jun;51(6):2013-7.'},{id:"B8",body:'Golper TA, Ward RA: Dialysate... Ho-hum! Clin J Am Soc Nephrol. 2009 Sep;4(9):1403-4. Epub 2009 Aug 20.'}],footnotes:[],contributors:[{corresp:null,contributorFullName:"Peter Ahrenholz",address:null,affiliation:'
BioArtProducts GmbH Rostock, Rostock, Germany
'},{corresp:"yes",contributorFullName:"Roland E. Winkler",address:"roland.winkler@praxisverbund-rostock.de",affiliation:'
Praxisverbund Dialyse und Apherese Rostock, Rostock, Germany
'}],corrections:null},book:{id:"4547",title:"Updates in Hemodialysis",subtitle:null,fullTitle:"Updates in Hemodialysis",slug:"updates-in-hemodialysis",publishedDate:"September 9th 2015",bookSignature:"Hiromichi Suzuki",coverURL:"https://cdn.intechopen.com/books/images_new/4547.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",editors:[{id:"156403",title:"Prof.",name:"Hiromichi",middleName:null,surname:"Suzuki",slug:"hiromichi-suzuki",fullName:"Hiromichi Suzuki"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},chapters:[{id:"47957",title:"Vascular Calcification in Patients with End-Stage Renal Disease",slug:"vascular-calcification-in-patients-with-end-stage-renal-disease",totalDownloads:1352,totalCrossrefCites:1,signatures:"Kosaku Nitta",authors:[{id:"172174",title:"Dr.",name:"Kosaku",middleName:null,surname:"Nitta",fullName:"Kosaku Nitta",slug:"kosaku-nitta"}]},{id:"47736",title:"Uremic Pruritus; Its Prevalence, Pathophysiology and Management",slug:"uremic-pruritus-its-prevalence-pathophysiology-and-management",totalDownloads:1481,totalCrossrefCites:3,signatures:"Pornanong Aramwit and Ouppatham Supasyndh",authors:[{id:"157050",title:"Prof.",name:"Dr. Pornanong",middleName:null,surname:"Aramwit",fullName:"Dr. Pornanong Aramwit",slug:"dr.-pornanong-aramwit"}]},{id:"47751",title:"Treatment Option for Uremic Pruritus",slug:"treatment-option-for-uremic-pruritus",totalDownloads:1321,totalCrossrefCites:0,signatures:"Hiromichi Suzuki, Hiroshi Omata and Hiroo Kumagai",authors:[{id:"156403",title:"Prof.",name:"Hiromichi",middleName:null,surname:"Suzuki",fullName:"Hiromichi Suzuki",slug:"hiromichi-suzuki"}]},{id:"47950",title:"Iatrogenic Iron Overload in Dialysis Patients",slug:"iatrogenic-iron-overload-in-dialysis-patients",totalDownloads:1347,totalCrossrefCites:0,signatures:"Guy Rostoker, Mireille Griuncelli, Christelle Loridon and Yves Cohen",authors:[{id:"155148",title:"Dr.",name:"Guy",middleName:null,surname:"Rostoker",fullName:"Guy Rostoker",slug:"guy-rostoker"}]},{id:"47719",title:"Bone Fragility in Hemodialysis Patients",slug:"bone-fragility-in-hemodialysis-patients",totalDownloads:928,totalCrossrefCites:0,signatures:"Shozo Yano",authors:[{id:"172372",title:"Dr.",name:"Shozo",middleName:null,surname:"Yano",fullName:"Shozo Yano",slug:"shozo-yano"}]},{id:"47788",title:"Dyspepsia — An Underestimated Problem among End-stage Renal Disease Patients",slug:"dyspepsia-an-underestimated-problem-among-end-stage-renal-disease-patients",totalDownloads:1164,totalCrossrefCites:0,signatures:"Paulo Roberto Santos",authors:[{id:"46690",title:"Ph.D.",name:"Paulo",middleName:"Roberto",surname:"Santos",fullName:"Paulo Santos",slug:"paulo-santos"}]},{id:"48132",title:"Aspects of Renal Disease Affecting Dental Management — Surgery in Patients Receiving Hemodyalisis",slug:"aspects-of-renal-disease-affecting-dental-management-surgery-in-patients-receiving-hemodyalisis",totalDownloads:1709,totalCrossrefCites:0,signatures:"M. Dencheva, E. Deliverska, A. Krasteva, J. Galabov and A. Kisselova",authors:[{id:"32422",title:"Dr.",name:"Asya",middleName:"Zaharieva",surname:"Krasteva",fullName:"Asya Krasteva",slug:"asya-krasteva"},{id:"48928",title:"Prof.",name:"Angelina",middleName:null,surname:"Kisselova",fullName:"Angelina Kisselova",slug:"angelina-kisselova"},{id:"172716",title:"Associate Prof.",name:"Elitsa",middleName:null,surname:"Deliverska",fullName:"Elitsa Deliverska",slug:"elitsa-deliverska"},{id:"173204",title:"Dr.",name:"Maria",middleName:null,surname:"Dencheva",fullName:"Maria Dencheva",slug:"maria-dencheva"},{id:"173205",title:"Dr.",name:"Jordan",middleName:null,surname:"Galabov",fullName:"Jordan Galabov",slug:"jordan-galabov"}]},{id:"48144",title:"Prevention and Management of Nosocomial Pneumonia in Hemodialysis Patients",slug:"prevention-and-management-of-nosocomial-pneumonia-in-hemodialysis-patients",totalDownloads:902,totalCrossrefCites:0,signatures:"Shu Wakino, Hitoshi Minakuchi, Hajime Inamoto and Hiroshi Itoh",authors:[{id:"172370",title:"Dr.",name:"Shu",middleName:null,surname:"Wakino",fullName:"Shu Wakino",slug:"shu-wakino"}]},{id:"47748",title:"Renal Cell Carcinoma in End-Stage Renal Disease",slug:"renal-cell-carcinoma-in-end-stage-renal-disease",totalDownloads:1299,totalCrossrefCites:0,signatures:"Yasukazu Nakanishi, Fumitaka Koga, Hiroshi Fukushima, Toru\nMotoi and Ken-ichi Tobisu",authors:[{id:"103104",title:"Dr.",name:"Fumitaka",middleName:null,surname:"Koga",fullName:"Fumitaka Koga",slug:"fumitaka-koga"}]},{id:"48020",title:"Dialysis Membranes — Physicochemical Structures and Features",slug:"dialysis-membranes-physicochemical-structures-and-features",totalDownloads:4580,totalCrossrefCites:3,signatures:"Akihiro C. Yamashita and Kenji Sakurai",authors:[{id:"171999",title:"Prof.",name:"Akihiro",middleName:null,surname:"Yamashita",fullName:"Akihiro Yamashita",slug:"akihiro-yamashita"}]},{id:"47460",title:"The Role of the Dialysate Flow Rate in Haemodialysis",slug:"the-role-of-the-dialysate-flow-rate-in-haemodialysis",totalDownloads:2644,totalCrossrefCites:0,signatures:"Peter Ahrenholz, Roland E. Winkler and Diego Zendeh-Zartochti",authors:[{id:"43902",title:"Dr.",name:"Roland",middleName:"E.",surname:"Winkler, M.B.A.",fullName:"Roland Winkler, M.B.A.",slug:"roland-winkler-m.b.a."}]},{id:"47753",title:"Principles and Practices of Haemodiafiltration",slug:"principles-and-practices-of-haemodiafiltration",totalDownloads:1647,totalCrossrefCites:0,signatures:"Eric T. Chou, Ross S. Francis, David W. Mudge, Carmel M. Hawley\nand David W. Johnson",authors:[{id:"50425",title:"Prof.",name:"David",middleName:null,surname:"Johnson",fullName:"David Johnson",slug:"david-johnson"},{id:"172327",title:"Dr.",name:"Eric",middleName:null,surname:"Chou",fullName:"Eric Chou",slug:"eric-chou"},{id:"172328",title:"Dr.",name:"David",middleName:null,surname:"Mudge",fullName:"David Mudge",slug:"david-mudge"},{id:"172329",title:"Dr.",name:"Carmel",middleName:null,surname:"Hawley",fullName:"Carmel Hawley",slug:"carmel-hawley"},{id:"172331",title:"Dr.",name:"Ross",middleName:null,surname:"Francis",fullName:"Ross Francis",slug:"ross-francis"}]},{id:"47722",title:"Water Treatment for Centre and Home-Based Haemodialysis",slug:"water-treatment-for-centre-and-home-based-haemodialysis",totalDownloads:2504,totalCrossrefCites:2,signatures:"Shyam Dheda, Carolyn Van Eps, Carmel Hawley and David W.\nJohnson",authors:[{id:"50425",title:"Prof.",name:"David",middleName:null,surname:"Johnson",fullName:"David Johnson",slug:"david-johnson"},{id:"172329",title:"Dr.",name:"Carmel",middleName:null,surname:"Hawley",fullName:"Carmel Hawley",slug:"carmel-hawley"},{id:"172514",title:"Dr.",name:"Shyam",middleName:null,surname:"Dheda",fullName:"Shyam Dheda",slug:"shyam-dheda"}]},{id:"47729",title:"Vascular Access and New Trends",slug:"vascular-access-and-new-trends",totalDownloads:1541,totalCrossrefCites:1,signatures:"Eirini Grapsa and Konstantinos Pantelias",authors:[{id:"49421",title:"Prof.",name:"Eirini",middleName:null,surname:"Grapsa",fullName:"Eirini Grapsa",slug:"eirini-grapsa"},{id:"52276",title:"Dr.",name:"Konstantinos",middleName:null,surname:"Pantelias",fullName:"Konstantinos Pantelias",slug:"konstantinos-pantelias"}]}]},relatedBooks:[{type:"book",id:"3267",title:"Hemodialysis",subtitle:null,isOpenForSubmission:!1,hash:"960f1c2998be5bdb86d0b9412f13fb0b",slug:"hemodialysis",bookSignature:"Hiromichi Suzuki",coverURL:"https://cdn.intechopen.com/books/images_new/3267.jpg",editedByType:"Edited by",editors:[{id:"156403",title:"Prof.",name:"Hiromichi",surname:"Suzuki",slug:"hiromichi-suzuki",fullName:"Hiromichi Suzuki"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"},chapters:[{id:"42994",title:"Cardiovascular Disease in Hemodialysis Patients",slug:"cardiovascular-disease-in-hemodialysis-patients",signatures:"Han Li and Shixiang Wang",authors:[{id:"157642",title:"Dr",name:null,middleName:null,surname:"Wang",fullName:"Wang",slug:"wang"}]},{id:"42054",title:"Medical Nutrition Therapy for Hemodialysis Patients",slug:"medical-nutrition-therapy-for-hemodialysis-patients",signatures:"F. Esra Günes",authors:[{id:"163743",title:"Ph.D.",name:"Esra",middleName:"Fatma",surname:"Güneş",fullName:"Esra Güneş",slug:"esra-gunes"}]},{id:"42995",title:"Rare Inherited Diseases Among Hemodialysis Patients",slug:"rare-inherited-diseases-among-hemodialysis-patients",signatures:"Ane Cláudia Fernandes Nunes, Fernanda de Souza Messias and Elvino José Guardão Barros",authors:[{id:"55270",title:"Prof.",name:"Ane C.F.",middleName:null,surname:"Nunes",fullName:"Ane C.F. Nunes",slug:"ane-c.f.-nunes"},{id:"166503",title:"Ms.",name:"Fernanda",middleName:null,surname:"Messias",fullName:"Fernanda Messias",slug:"fernanda-messias"},{id:"166504",title:"Prof.",name:"Elvino",middleName:null,surname:"Barros",fullName:"Elvino Barros",slug:"elvino-barros"}]},{id:"43000",title:"Bleeding Diathesis in Hemodialysis Patients",slug:"bleeding-diathesis-in-hemodialysis-patients",signatures:"Gülsüm Özkan and Şükrü Ulusoy",authors:[{id:"48454",title:"Dr.",name:"Gülsüm",middleName:null,surname:"Özkan",fullName:"Gülsüm Özkan",slug:"gulsum-ozkan"},{id:"51497",title:"Prof.",name:"Şükrü",middleName:null,surname:"Ulusoy",fullName:"Şükrü Ulusoy",slug:"sukru-ulusoy"}]},{id:"43011",title:"Pathogenesis and Treatment of Chronic Kidney Disease- Mineral and Bone Disorder",slug:"pathogenesis-and-treatment-of-chronic-kidney-disease-mineral-and-bone-disorder",signatures:"Yasuo Imanishi, Yoshiki Nishizawa and Masaaki Inaba",authors:[{id:"156222",title:"Dr.",name:"Yasuo",middleName:null,surname:"Imanishi",fullName:"Yasuo Imanishi",slug:"yasuo-imanishi"},{id:"166318",title:"Prof.",name:"Yoshiki",middleName:null,surname:"Nishizawa",fullName:"Yoshiki Nishizawa",slug:"yoshiki-nishizawa"},{id:"166319",title:"Prof.",name:"Masaaki",middleName:null,surname:"Inaba",fullName:"Masaaki Inaba",slug:"masaaki-inaba"}]},{id:"43014",title:"Lipid Abnormalities in Hemodialysis Patients",slug:"lipid-abnormalities-in-hemodialysis-patients",signatures:"Şükrü Ulusoy and Gülsüm Özkan",authors:[{id:"48454",title:"Dr.",name:"Gülsüm",middleName:null,surname:"Özkan",fullName:"Gülsüm Özkan",slug:"gulsum-ozkan"},{id:"51497",title:"Prof.",name:"Şükrü",middleName:null,surname:"Ulusoy",fullName:"Şükrü Ulusoy",slug:"sukru-ulusoy"}]},{id:"40473",title:"Remnant Proteinuria in Chronic Hemodialysis",slug:"remnant-proteinuria-in-chronic-hemodialysis",signatures:"Hernán Trimarchi",authors:[{id:"56043",title:"Dr.",name:"Hernan",middleName:null,surname:"Trimarchi",fullName:"Hernan Trimarchi",slug:"hernan-trimarchi"}]},{id:"43024",title:"Glycemic Control in Diabetic Patients on Long-Term Maintenance Dialysis",slug:"glycemic-control-in-diabetic-patients-on-long-term-maintenance-dialysis",signatures:"Pornanong Aramwit and Bancha Satirapoj",authors:[{id:"54460",title:"Dr.",name:"Bancha",middleName:null,surname:"Satirapoj",fullName:"Bancha Satirapoj",slug:"bancha-satirapoj"},{id:"157050",title:"Prof.",name:"Dr. Pornanong",middleName:null,surname:"Aramwit",fullName:"Dr. Pornanong Aramwit",slug:"dr.-pornanong-aramwit"}]},{id:"43028",title:"Epidemiology of Chronic Dialysis Patients in the Intensive Care Unit",slug:"epidemiology-of-chronic-dialysis-patients-in-the-intensive-care-unit",signatures:"Melanie Chan and Marlies Ostermann",authors:[{id:"39346",title:"Dr.",name:"Marlies",middleName:null,surname:"Ostermann",fullName:"Marlies Ostermann",slug:"marlies-ostermann"},{id:"158556",title:"Dr.",name:"Melanie",middleName:null,surname:"Chan",fullName:"Melanie Chan",slug:"melanie-chan"}]},{id:"43030",title:"Disturbances in Acid-Base Balance in Patients on Hemodialysis",slug:"disturbances-in-acid-base-balance-in-patients-on-hemodialysis",signatures:"Alexandre Braga Libório and Tacyano Tavares Leite",authors:[{id:"157228",title:"Prof.",name:"Alexandre",middleName:null,surname:"Liborio",fullName:"Alexandre Liborio",slug:"alexandre-liborio"}]},{id:"41865",title:"More than Half of Patients Receiving Hemodialysis with Leg Ulcer Require Amputation",slug:"more-than-half-of-patients-receiving-hemodialysis-with-leg-ulcer-require-amputation",signatures:"Masaki Fujioka",authors:[{id:"53197",title:"Prof.",name:"Masaki",middleName:null,surname:"Fujioka",fullName:"Masaki Fujioka",slug:"masaki-fujioka"}]},{id:"41897",title:"Helicobacterpylori Infection for Hemodialysis Patients",slug:"helicobacterpylori-infection-for-hemodialysis-patients",signatures:"Yoshiaki Kawaguchi and Tetsuya Mine",authors:[{id:"57911",title:"Dr.",name:"Yoshiaki",middleName:null,surname:"Kawaguchi",fullName:"Yoshiaki Kawaguchi",slug:"yoshiaki-kawaguchi"}]},{id:"43079",title:"Site and Size of Vascular Calcifications Are Different in Dialysis Patients with Various Underlying Diseases",slug:"site-and-size-of-vascular-calcifications-are-different-in-dialysis-patients-with-various-underlying-",signatures:"H. Suzuki, T. Inoue, H. Okada, T. Takenaka, Kunihiko Hayashi, Jyunnichi Nishiyama, Takashi Yamazaki, Yuji Nishiyama and Keiko Kaneko",authors:[{id:"156403",title:"Prof.",name:"Hiromichi",middleName:null,surname:"Suzuki",fullName:"Hiromichi Suzuki",slug:"hiromichi-suzuki"}]},{id:"43083",title:"Colloids in Dialytic Refractory Hypotension",slug:"colloids-in-dialytic-refractory-hypotension",signatures:"Guy Rostoker",authors:[{id:"155148",title:"Dr.",name:"Guy",middleName:null,surname:"Rostoker",fullName:"Guy Rostoker",slug:"guy-rostoker"}]},{id:"40441",title:"Current Anemia Treatment in Hemodialysis Patients: The Challenge for Secure Use of Erythropoietin-Stimulating Agents",slug:"current-anemia-treatment-in-hemodialysis-patients-the-challenge-for-secure-use-of-erythropoietin-sti",signatures:"Paulo Roberto Santos",authors:[{id:"46690",title:"Ph.D.",name:"Paulo",middleName:"Roberto",surname:"Santos",fullName:"Paulo Santos",slug:"paulo-santos"}]},{id:"43085",title:"rhEPO for the Treatment of Erythropoietin Resistant Anemia in Hemodialysis Patients – Risks and Benefits",slug:"rhepo-for-the-treatment-of-erythropoietin-resistant-anemia-in-hemodialysis-patients-risks-and-benefi",signatures:"Sandra Ribeiro, Elísio Costa, Luís Belo, Flávio Reis and Alice Santos- Silva",authors:[{id:"157678",title:"Ph.D.",name:"Elísio",middleName:null,surname:"Costa",fullName:"Elísio Costa",slug:"elisio-costa"}]},{id:"40538",title:"Management of Anemia on Hemodialysis",slug:"management-of-anemia-on-hemodialysis",signatures:"Konstantinos Pantelias and Eirini Grapsa",authors:[{id:"49421",title:"Prof.",name:"Eirini",middleName:null,surname:"Grapsa",fullName:"Eirini Grapsa",slug:"eirini-grapsa"},{id:"52276",title:"Dr.",name:"Konstantinos",middleName:null,surname:"Pantelias",fullName:"Konstantinos Pantelias",slug:"konstantinos-pantelias"}]},{id:"43087",title:"Analysis of the Dialysis Dose in Different Clinical Situations: A Simulation-Based Approach",slug:"analysis-of-the-dialysis-dose-in-different-clinical-situations-a-simulation-based-approach",signatures:"Rodolfo Valtuille, Manuel Sztejnberg and Elmer. A. Fernandez",authors:[{id:"50757",title:"Prof.",name:"Elmer",middleName:"Andres",surname:"Fernandez",fullName:"Elmer Fernandez",slug:"elmer-fernandez"},{id:"59435",title:"Prof.",name:"Rodolfo",middleName:"Amilcar",surname:"Valtuille",fullName:"Rodolfo Valtuille",slug:"rodolfo-valtuille"},{id:"166642",title:"Dr.",name:"Manuel",middleName:null,surname:"Sztejnberg",fullName:"Manuel Sztejnberg",slug:"manuel-sztejnberg"}]},{id:"43103",title:"Adsorption in Extracorporeal Blood Purification: How to Enhance Solutes Removal Beyond Diffusion and Convection",slug:"adsorption-in-extracorporeal-blood-purification-how-to-enhance-solutes-removal-beyond-diffusion-and-",signatures:"Fabio Grandi, Piergiorgio Bolasco, Giuseppe Palladino, Luisa Sereni, Marialuisa Caiazzo, Mauro Atti and Paolo Maria Ghezzi",authors:[{id:"50721",title:"Dr",name:"Fabio",middleName:null,surname:"Grandi",fullName:"Fabio Grandi",slug:"fabio-grandi"},{id:"165439",title:"Dr.",name:"Piergiorgio",middleName:null,surname:"Bolasco",fullName:"Piergiorgio Bolasco",slug:"piergiorgio-bolasco"},{id:"165440",title:"Ph.D.",name:"Giuseppe",middleName:null,surname:"Palladino",fullName:"Giuseppe Palladino",slug:"giuseppe-palladino"},{id:"165441",title:"Mrs.",name:"Luisa",middleName:null,surname:"Sereni",fullName:"Luisa Sereni",slug:"luisa-sereni"},{id:"165442",title:"Dr.",name:"Paolo Maria",middleName:null,surname:"Ghezzi",fullName:"Paolo Maria Ghezzi",slug:"paolo-maria-ghezzi"},{id:"165445",title:"Ph.D.",name:"Marialuisa",middleName:null,surname:"Caiazzo",fullName:"Marialuisa Caiazzo",slug:"marialuisa-caiazzo"},{id:"165817",title:"Dr.",name:"Mauro",middleName:null,surname:"Atti",fullName:"Mauro Atti",slug:"mauro-atti"}]},{id:"43105",title:"Advances in Hemodialysis Techniques",slug:"advances-in-hemodialysis-techniques",signatures:"Ayman Karkar",authors:[{id:"156627",title:"Dr.",name:"Ayman",middleName:null,surname:"Karkar",fullName:"Ayman Karkar",slug:"ayman-karkar"}]},{id:"43116",title:"Implementation and Management of Strategies to Set and to Achieve Clinical Targets",slug:"implementation-and-management-of-strategies-to-set-and-to-achieve-clinical-targets",signatures:"Bernard Canaud, Ciro Tetta, Daniele Marcelli, Guido Giordana, Stefano Stuard, Katrin Koehler, Flavio Mari, Carlo Barbieri, Miryana Dobreva, Andrea Stopper and Emanuele Gatti",authors:[{id:"53161",title:"Prof.",name:"Ciro",middleName:null,surname:"Tetta",fullName:"Ciro Tetta",slug:"ciro-tetta"},{id:"58896",title:"Prof.",name:"Emanuele",middleName:null,surname:"Gatti",fullName:"Emanuele Gatti",slug:"emanuele-gatti"}]},{id:"43102",title:"Push/Pull Based Renal Replacement Treatments",slug:"push-pull-based-renal-replacement-treatments",signatures:"Kyungsoo Lee",authors:[{id:"53225",title:"Dr.",name:"Kyungsoo",middleName:null,surname:"Lee",fullName:"Kyungsoo Lee",slug:"kyungsoo-lee"}]},{id:"41914",title:"Select Ion and Preparation of Patients for Dialysis",slug:"select-ion-and-preparation-of-patients-for-dialysis",signatures:"Pierpaolo Di Cocco, Antonio Famulari, Francesco Pisani, Linda De Luca, Vinicio Rizza and Katia Clemente",authors:[{id:"40458",title:"Dr.",name:"Pierpaolo",middleName:null,surname:"Di Cocco",fullName:"Pierpaolo Di Cocco",slug:"pierpaolo-di-cocco"},{id:"40460",title:"Prof.",name:"Antonio",middleName:null,surname:"Famulari",fullName:"Antonio Famulari",slug:"antonio-famulari"},{id:"40461",title:"Prof.",name:"Francesco",middleName:null,surname:"Pisani",fullName:"Francesco Pisani",slug:"francesco-pisani"},{id:"84933",title:"Dr.",name:"Katia",middleName:null,surname:"Clemente",fullName:"Katia Clemente",slug:"katia-clemente"},{id:"128362",title:"Dr.",name:"Linda",middleName:null,surname:"De Luca",fullName:"Linda De Luca",slug:"linda-de-luca"},{id:"166021",title:"Dr.",name:"Vinicio",middleName:null,surname:"Rizza",fullName:"Vinicio Rizza",slug:"vinicio-rizza"}]},{id:"43095",title:"Reduction of Heparin and Oxidative Potential by Means of Citrasate® in High-Flux Dialysis (HFD) and Online Hemodiafiltration (olHDF) in Pre and Postdilution",slug:"reduction-of-heparin-and-oxidative-potential-by-means-of-citrasate-in-high-flux-dialysis-hfd-and-onl",signatures:"Roland E. Winkler, Peter Ahrenholz, Wolfgang Paetow, Grit Waitz and Hartmut Wolf",authors:[{id:"43902",title:"Dr.",name:"Roland",middleName:"E.",surname:"Winkler, M.B.A.",fullName:"Roland Winkler, M.B.A.",slug:"roland-winkler-m.b.a."},{id:"50745",title:"Dr.",name:"Peter",middleName:null,surname:"Ahrenholz",fullName:"Peter Ahrenholz",slug:"peter-ahrenholz"},{id:"165534",title:"Dr.",name:"Wolfgang",middleName:null,surname:"Paetow",fullName:"Wolfgang Paetow",slug:"wolfgang-paetow"},{id:"165535",title:"Dr.",name:"Grit",middleName:null,surname:"Waitz",fullName:"Grit Waitz",slug:"grit-waitz"},{id:"165536",title:"Prof.",name:"Hartmut",middleName:null,surname:"Wolf",fullName:"Hartmut Wolf",slug:"hartmut-wolf"}]},{id:"43093",title:"The Controversial Vascular Access for Hemodialysis – Own Experience",slug:"the-controversial-vascular-access-for-hemodialysis-own-experience",signatures:"M. Dziekiewicz, G. Kade, Z. Wańkowicz and M. Maruszyński",authors:[{id:"155836",title:"Ph.D.",name:"Miroslaw",middleName:null,surname:"Dziekiewicz",fullName:"Miroslaw Dziekiewicz",slug:"miroslaw-dziekiewicz"},{id:"167396",title:"Dr.",name:"Grzegorz",middleName:null,surname:"Kade",fullName:"Grzegorz Kade",slug:"grzegorz-kade"},{id:"167397",title:"Prof.",name:"Zofia",middleName:null,surname:"Wańkowicz",fullName:"Zofia Wańkowicz",slug:"zofia-wankowicz"},{id:"167398",title:"Prof.",name:"Marek",middleName:null,surname:"Maruszynski",fullName:"Marek Maruszynski",slug:"marek-maruszynski"}]},{id:"43091",title:"Vascular Access With or Without Synthetic GOR-TEX",slug:"vascular-access-with-or-without-synthetic-gor-tex",signatures:"Seyed Reza Mousavi",authors:[{id:"44950",title:"Prof.",name:"Seyed Reza",middleName:null,surname:"Mousavi",fullName:"Seyed Reza Mousavi",slug:"seyed-reza-mousavi"}]},{id:"43097",title:"A Holistic Approach to Vascular Access in Hemodialysis",slug:"a-holistic-approach-to-vascular-access-in-hemodialysis",signatures:"Naushad Junglee, Anna Owen, Mahdi Jibani and Dean Williams",authors:[{id:"156552",title:"Dr.",name:"Naushad",middleName:"Ali",surname:"Junglee",fullName:"Naushad Junglee",slug:"naushad-junglee"},{id:"157440",title:"Dr.",name:"Mahdi",middleName:null,surname:"Jibani",fullName:"Mahdi Jibani",slug:"mahdi-jibani"},{id:"157442",title:"Ms.",name:"Anna",middleName:null,surname:"Owen",fullName:"Anna Owen",slug:"anna-owen"},{id:"157443",title:"Mr.",name:"Dean",middleName:null,surname:"Williams",fullName:"Dean Williams",slug:"dean-williams"}]},{id:"43084",title:"Vascular Access for Hemodialysis - How to Maintain in Clinical Practice",slug:"vascular-access-for-hemodialysis-how-to-maintain-in-clinical-practice",signatures:"Hossam Elwakeel and Khaled Elalfy",authors:[{id:"156088",title:"Dr.",name:"Hossam",middleName:null,surname:"Elwakeel",fullName:"Hossam Elwakeel",slug:"hossam-elwakeel"}]},{id:"43075",title:"Single-Needle Hemodialysis on Native Fistulae",slug:"single-needle-hemodialysis-on-native-fistulae",signatures:"Guy Rostoker",authors:[{id:"155148",title:"Dr.",name:"Guy",middleName:null,surname:"Rostoker",fullName:"Guy Rostoker",slug:"guy-rostoker"}]},{id:"42590",title:"Complications of Autogenous Arteriovenous Fistulas",slug:"complications-of-autogenous-arteriovenous-fistulas",signatures:"Lucian Florin Dorobanţu, Ovidiu Ştiru, Cristian Bulescu, Şerban Bubenek and Vlad Anton Iliescu",authors:[{id:"48397",title:"Dr.",name:"Lucian Florin",middleName:null,surname:"Dorobantu",fullName:"Lucian Florin Dorobantu",slug:"lucian-florin-dorobantu"}]},{id:"41864",title:"Hemodialysis Access: Initial Considerations and the Difficult Patient",slug:"hemodialysis-access-initial-considerations-and-the-difficult-patient",signatures:"Laura A. Peterson, Maria Litzendorf, Hooman Khabiri and Stanislaw P. A. Stawicki",authors:[{id:"44943",title:"Prof.",name:"Stanislaw P. A.",middleName:null,surname:"Stawicki",fullName:"Stanislaw P. A. Stawicki",slug:"stanislaw-p.-a.-stawicki"},{id:"157927",title:"Dr.",name:"Laura",middleName:null,surname:"Peterson",fullName:"Laura Peterson",slug:"laura-peterson"},{id:"157928",title:"Dr.",name:"Hooman",middleName:null,surname:"Khabiri",fullName:"Hooman Khabiri",slug:"hooman-khabiri"},{id:"166321",title:"Dr.",name:"Maria",middleName:null,surname:"Litzendorf",fullName:"Maria Litzendorf",slug:"maria-litzendorf"}]},{id:"40903",title:"Vascular Access for Hemodialysis - Overview and Emphasis on Complications",slug:"vascular-access-for-hemodialysis-overview-and-emphasis-on-complications",signatures:"Octavio J. Salgado",authors:[{id:"157170",title:"Dr.",name:"Octavio",middleName:"J.",surname:"Salgado",fullName:"Octavio Salgado",slug:"octavio-salgado"}]},{id:"43069",title:"Catheter-Related Sheaths (CRS): Pathophysiology and Treatment Strategies",slug:"catheter-related-sheaths-crs-pathophysiology-and-treatment-strategies",signatures:"Robert Percarpio, Elizabeth T. Chorney and Andrew R. Forauer",authors:[{id:"157540",title:"Dr.",name:"Andrew",middleName:null,surname:"Forauer",fullName:"Andrew Forauer",slug:"andrew-forauer"},{id:"157543",title:"Dr.",name:"Robert",middleName:null,surname:"Percarpio",fullName:"Robert Percarpio",slug:"robert-percarpio"},{id:"166202",title:"Dr.",name:"Elizabeth",middleName:null,surname:"Chorney",fullName:"Elizabeth Chorney",slug:"elizabeth-chorney"}]},{id:"43066",title:"Arteriovenous Fistula or Catheter: Creating an Optimal Vascular Access for Hemodialysis",slug:"arteriovenous-fistula-or-catheter-creating-an-optimal-vascular-access-for-hemodialysis",signatures:"Joëlle Cridlig, Michèle Kessler and Thanh Cao-Huu",authors:[{id:"62828",title:"Ms.",name:"Michčle",middleName:null,surname:"Kessler",fullName:"Michčle Kessler",slug:"michcle-kessler"},{id:"166071",title:"Dr.",name:"Hervé",middleName:null,surname:"Boccaccini",fullName:"Hervé Boccaccini",slug:"herve-boccaccini"},{id:"166072",title:"Dr.",name:"Sylvie",middleName:null,surname:"Béot",fullName:"Sylvie Béot",slug:"sylvie-beot"},{id:"166893",title:"Dr.",name:"Joëlle",middleName:null,surname:"Cridlig",fullName:"Joëlle Cridlig",slug:"joelle-cridlig"}]},{id:"43064",title:"Renal Rehabilitation: Present and Future Perspectives",slug:"renal-rehabilitation-present-and-future-perspectives",signatures:"Masahiro Kohzuki",authors:[{id:"155814",title:"Prof.",name:"Masahiro",middleName:null,surname:"Kohzuki",fullName:"Masahiro Kohzuki",slug:"masahiro-kohzuki"}]},{id:"43052",title:"Exercise Therapy – Additional Tool for Managing Physical and Psychological Problems on Hemodialysis",slug:"exercise-therapy-additional-tool-for-managing-physical-and-psychological-problems-on-hemodialysis",signatures:"Andrea Mahrova and Klara Svagrova",authors:[{id:"155058",title:"Dr.",name:"Andrea",middleName:null,surname:"Mahrova",fullName:"Andrea Mahrova",slug:"andrea-mahrova"},{id:"156505",title:"MSc.",name:"Klara",middleName:null,surname:"Svagrova",fullName:"Klara Svagrova",slug:"klara-svagrova"}]},{id:"41913",title:"Quality of Life in Patients Undergoing Hemodialysis",slug:"quality-of-life-in-patients-undergoing-hemodialysis",signatures:"Mukadder Mollaoğlu",authors:[{id:"43900",title:"Prof.",name:"Mukadder",middleName:null,surname:"Mollaoğlu",fullName:"Mukadder Mollaoğlu",slug:"mukadder-mollaoglu"}]},{id:"43050",title:"Physiotherapy in the Patients on Hemodialysis",slug:"physiotherapy-in-the-patients-on-hemodialysis",signatures:"S. Ufuk Yurdalan",authors:[{id:"83844",title:"Prof.",name:"Ufuk",middleName:"Saadet",surname:"Yurdalan",fullName:"Ufuk Yurdalan",slug:"ufuk-yurdalan"}]}]}]},onlineFirst:{chapter:{type:"chapter",id:"75032",title:"Optimization Directions for Monitoring of Ground Freezing Process for Grzegorz Shaft Sinking",doi:"10.5772/intechopen.95885",slug:"optimization-directions-for-monitoring-of-ground-freezing-process-for-grzegorz-shaft-sinking",body:'
1. Introduction. Grzegorz shaft: The first shaft in Silesian Coal Basin sunk using ground freezing method in 21st century
Grzegorz shaft is one of the biggest today’s projects in Polish mining industry. Difficult conditions in its geological cross-section forced application of special shaft sinking method, which is ground freezing. This method was in common use in Silesian Coal Basin back in the days, but nowadays it is rarely used, mostly because of a small number of new shafts sunk. This venture was entrusted to Shaft Sinking Company (PBSz S.A.), part of the JSW Group and a leader of highly specialized mining services market in Poland. Company has got 75 years of experience in shaft sinking, including projects in extremely hard conditions, as well as in use of ground freezing method [1].
Application of typical shaft sinking method in case of Grzegorz shaft is impossible because of high rock mass’ water accumulation and rock’s low soaking resilience. Utilization of different methods, such as rock mass drainage and grouting, were analyzed, but expected low effectiveness effected in their abandonment. As the most effective, safe and reliable, ground freezing method was chosen for purpose of Grzegorz shaft sinking. Its essence is creating a column of frozen ground and it is realized by pumping freezing medium to boreholes. Mine shaft is sunk in such prepared rock mass using traditional methods, such as drill sand blasts. Column of frozen soils and rocks prevents shaft heading from flooding. It can also play a role of sidewall’s support, as frozen rocks and soils are characterized by higher strength than those in natural state. Principles of ground freezing method and solution used for Grzegorz shaft sinking was described in details in following sections [1, 2, 3].
Grzegorz shaft was designed as a downcast, man and material shaft. Its inner cross-section is circle with a diameter of 7,5 m. Ordinate of surface level is +258,0 m and its depth is 870,0 m [3].
Shaft sinking is a huge and complicated venture, especially in terms of difficult geological conditions. However, Grzegorz shaft sinking is characterized by high level of innovativeness. One of the biggest innovations is application of the same head frame for both processes of sinking and regular operation of Grzegorz shaft. It is a first such case in Polish coal mining. Up to now, every mine shaft in Polish collieries was sunk using head frame of special construction, which were then disassembled and final head frame was built. But innovative way of thinking applies also to other areas of design and construction of Grzegorz shaft. Geophysical survey was conducted to determine new directions of optimization for processes of shaft sinking in a frozen rock mass and monitoring of ground freezing process [3].
2. Ground freezing method
The essence of special method of shaft sinking, which is ground freezing method is freezing of aquifers and then shaft sinking in frozen rock mass, using traditional methods, such as drills and blasts. It was primarily used in 1862 in England. Rock mass was frozen by freezing medium flow through a spiral pipe placed on a surface of quicksand’s layer. In 1883 in Archibald mine, located near Schneidlingen, rock mass was frozen using technology similar to the one used nowadays. In Siberia’s gold mines in 1940’s shaft sinking method utilizing natural ground freezing was commonly used. It was then neglected, because of low effectiveness [4].
Low temperatures needed for freezing of soils and rocks around sunk shaft are obtained by heat of freezing medium transition from liquid to gas. The most common freezing medium is ammonia NH3. Freezing boreholes are drilled around contour of the shaft. Distance between them is 0,9 to 1,2 m. They are equipped with casing pipe, so called freezing pipes, with diameter between 100 and 160 mm and pipes with diameter of 25–45 mm inside the freezing pipes. They are called inlet or inflow pipes, and are shorter than borehole depth (pipe do not reach borehole’s bottom). Freezing medium is brought to a freezing ring on the surface, where it is distributed to freezing boreholes. It is then pumped into the boreholes through inflow pipes. Freezing medium flows between casing and inlet pipes, cooling rocks and soils via conduction. Constant rock mass cooling leads to freezing of water inside soils and rocks. Column of frozen ground develops around the freezing borehole. Such columns around numerous boreholes combine with each other, which effects in development of one cylinder of frozen ground around the outline of the shaft. This column of frozen soils and rocks prevents shaft heading from flooding and resists pressure of water and rock mass [4, 5, 6, 7, 8, 9, 10, 11].
Various liquids can be pumped into freezing boreholes, such as aqueous solutions of calcium, sodium or magnesium chloride. All of them are characterized by low freezing temperature. The role of refrigerant is heat carrying, transferring it from rock mass to evaporator. It flows through freezing pipes in boreholes, collector and evaporator, where it is cooled down [4].
Strength of frozen rock or soil is higher than in natural state. The highest compressive strength characterizes frozen gravel and coarse-grained sand. Fine-grained sands and clays have lower compressive strength. Strength of frozen ground is also dependent on ice strength, which is related to ice grains’ size and freezing time. As rule of thumb, the faster freezing process the higher ice strength. Time of freezing depends on conductivity of casing pipes, freezing installation effectiveness and amount of heat to transfer [4, 5, 6, 7].
Project of ground freezing has to be preceded by precise geological and hydrogeological measurements in the vicinity of designed shaft. In particular, it is important to identify hydrogeological conditions, such as number of aquifers, their depth and range, water pressure and its chemism [4, 8].
3. Geological conditions
3.1 Geological structure
Hydrogeological, geological and engineering conditions were determined on basis of data collected from boreholes G-8 and G-8bis, drilled specifically for this purpose. Stratigraphic profile in axis of the designed Grzegorz shaft consists of:
Quaternary formations between 0,00 and 40,43 m – layers of sands, clay and aggregate;
Tertiary formations between 40,43 and 114,43 m – layers of slit, clay, aggregate, claystone and limestone;
Triassic formations between 114,3 and 234,93 m – layers of dolomite, limestone, clay, sandstone and mudstone;
Carboniferous formations below 234,93 m – layers of sandstone, claystone and hard coal.
3.2 Hydrogeological conditions
Four aquifers with sixteen water bearing horizons are located in Grzegorz shaft profile. In quaternary formations there are two water bearing horizons, both with confined water table. It is fed by rainwater. Reservoir rocks are clays, sands and aggregates. Tertiary aquifer consists of single water bearing horizon with confined water table. It is also fed by rainwater. Reservoir rock is a limestone. Three water bearing horizons occur in Triassic aquifer, all of them with confined water table, also fed by rainwater. Reservoir rocks are dolomite, limestone, mudstone and sandstone. There are ten water bearing horizons in Carboniferous aquifer. Reservoir rock for all of them is sandstone. All horizons are also characterized by confined water table. There are fed by water infiltrating from upper stratigraphic layers.
Estimated water infiltration to the shaft heading from different aquifers varies between 0,057 to 0,926 m3/min. Total expected water supply is equal 5,957 m3/min.
3.3 Engineering conditions
According to observations made during drilling G-8bis borehole and laboratory tests of core sample there are seven different geotechnical zones, characterized with different geotechnical parameters.
It was found that there are extremely difficult geological conditions in zones I, III, V and VI, caused by low soaking resilience of rocks and high accumulation of water. Shaft sinking in such conditions is impossible without utilization of special methods, because there is a real threat of problems with sidewalls’ stability. Occurrence of these geotechnical zones enforced utilization of ground freezing method for Grzegorz shaft sinking.
4. Freezing installation and boreholes’ construction
4.1 Freezing installation
Freezing installation consists of refrigeration plant (primary system) and secondary system and it is suited for cooling calcium chloride aqueous solution to −35°C [1, 3].
Primary system includes three freezing units, so called chillers PAC SAB 283 E eco, which freezing medium is ammonia. They are cooled by cooling towers Evapco AT 18-3 M14. Refrigeration plant consist also of isolated pipes for brine transfer, brine tank, discharge tank, water treatment station, eight pumps and armature. Model of refrigeration plant is presented on Figure 1.
Figure 1.
Refrigeration plant [3].
Secondary system is basically a channel used to transfer coolant from refrigeration plant to freezing boreholes. The channel consists of two main parts, one of them is a circle channel around the shaft outline (containing freezing ring), the other one is a channel between freezing ring and refrigeration plant.
Freezing channel contains two pipelines with diameter of 350 mm – inlet and outlet pipelines and one venting pipeline with diameter of 65 mm. Around the shaft outline, pipelines are circle-shaped and form so-called freezing ring. Freezing boreholes’ pipes are connected directly to the freezing ring. Model of secondary system of freezing installation and cross-sections of channels are shown on Figure 2.
Figure 2.
Freezing channel [3]. a) Freezing channel model, b) cross-section of freezing channel between refrigeration plant and shaft; c) freezing channel around the shaft; 1: Inlet pipeline, 2: Outlet pipeline, 3: Rack.
4.2 Freezing boreholes
For purpose of Grzegorz shaft sinking, 40 freezing and 3 control boreholes were designed and drilled. They are marked with numbers from M1 to M40 (freezing boreholes) and from T1 to T3 (control boreholes; one of them is previously drilled borehole G-8bis). Control boreholes are located on common axis, out of the freezing boreholes’ circle. Their task is to inspect shape and size of frozen ground column. Depth of all boreholes is equal 485 m (bottom 10 meters are filled with concrete) [12].
Distance between freezing boreholes varies in practice between 0,9 and 1,3 m. It is determined according to:
required size of frozen ground cylinder,
economic factors,
time required.
In case of Grzegorz shaft sinking distance between freezing boreholes was calculated at about 1,25 m. Parameters of freezing boreholes are presented in Table 1.
No.
Parameter
Value
1.
Number of freezing boreholes
40 pcs
2.
Distance between boerholes
1,25 m
3.
Diameter of freezing boreholes circle
16 m
4.
Depth of freezing boreholes
485 m (including 10 m of concrete)
5.
Casing pipes diameter
Ø139,7 mm × 8,0 mm
6.
Inflow pipes diameter
Ø75,0 × 4,5 mm
7.
Refrigerant
CaCl2 aqueous solution
Table 1.
Parameters of freezing boreholes.
Construction of freezing boreholes:
0–2,0 m – lining pipe Ø508 mm (20″)
2,0–40,0 m – borehole’s diameter Ø311 mm – 12 1/4″ (rotary drill bit Ø311 mm)
40–485 m – borehole’s diameter Ø216 mm – 8 1/2″ (rotary drill bit Ø216 mm)
Figure 3. presents arrangement of freezing and control boreholes and Grzegorz shaft’s cross-section. Description of shaft’s elements represents state of construction at the moment of beginning of drilling.
Figure 3.
Arrangement of freezing and control boreholes and cross-section of Grzegorz shaft [1].
5. Geophysical measurements
Monitoring of phenomena occurring in frozen rock mass is crucial for safety of the whole process of shaft sinking using ground freezing method. It is not an easy task, though. Number of geophysical measurements were conducted on Grzegorz shaft’s construction plant in order to optimize process of ground freezing and monitoring of frozen rock mass. On a basis of gathered data, practical aspects of presented methods were analyzed.
Potential measuring methods assumed possible to use for Grzegorz shaft monitoring were [13]:
vertical seismic profiling,
transmission tomography,
seismic interferometry,
surface wave analysis,
reflection seismology.
Surface waves analysis allows estimation of velocity of transverse wave behind the shaft lining, within few meters. Utilization of reflection seismology helps to anticipate geological faults and some of the parameters of rock mass. Especially prior recognition of faults plays critical role in safety of miners working in the shaft’s heading, as well as for economic factors. Application of proposed methods has to be carefully considered and tested in real-life condition. Unfortunately, it was impossible, because of the small depth (20 meters) of Grzegorz shaft during measurement session. Initial assumptions involve utilization of geophones in short distance from shaft’s heading [13].
An objective of tomography test is estimation of 2D wave velocity field between adjacent boreholes. Tests were carried out using vibration source of special construction, made especially for purpose of these tests. This device is presented on Figure 4. Two tests were made, first of them with utilization of probe consisting of four hydrophones with own frequency of 500 Hz and another one with using two probes equipped with three hydrophones with own frequency of 100 Hz [13].
Figure 4.
A view of vibration source prototype.
The results obtained prove that monitoring of the frozen rock mass column using probes and vibration source is possible. High financial expenditures needed for vibration source construction (prototype used for tests is suited for use in control boreholes, final vibration source for use in freezing boreholes has to be constructed) and problematic technology of testing caused neglecting of further development of such solution [13].
Utilization of scattered waves allows monitoring of deformational phenomena occurring in rock mass. The appearance of cracks, rifts and microfractures affects velocity of wave propagation and its amplitude. What is even more important in case of ground freezing is high sensitivity of coda wave velocity for (even small) temperature changes in rock mass [13, 14, 15, 16].
Utilization of seismic interferometry was proposed for purpose of monitoring of phenomena occurring in frozen rock mass caused by temperature changes in the vicinity of the Grzegorz shaft. Sources of seismic noise, which is needed for such measurements, are operating freezing boreholes. This method of monitoring provides near real-time information.
Tests were conducted to prove correctness of initial assumptions. Measurements were carried out using two probes consisting of three hydrophones with own frequency of 100 Hz each. Figure 5. presents 5-minute record of seismic noise. Channels 0, 1 and 2 represent hydrophones located in control borehole T2, channels 3, 4 and 5 represent hydrophones used in borehole T1, located closer to freezing boreholes. High amplitude values about 13:02 are caused by tests of vibration source used in the tomography measurements.
Figure 5.
Example of seismic noise record.
From the practical point of view, the most relevant is the period of stationary seismic noise. It is probably an effect of freezing boreholes operation and its frequency varies between 10 and 200 Hz. Figure 6. Presents record and spectrogram of channel 0. Spectrogram’s scale upper limit is 300 Hz.
Figure 6.
Record and spectrogram of channel 0.
On the basis of scattered wave interferometry correlation functions, representing estimated scattered wave propagation between hydrophones, were obtained. Further tests and analysis are required for purpose of utilization of this method for real life application, including tests covering long time period of measurement.
To sum up, coda wave interferometry method can be used in practice, for monitoring of ground freezing process and become convenient and reliable monitoring method. High sensitivity for temperature changes can prevent potential unexpected failures, which are real threat for miners working in the shaft heading and for shaft itself. However, this method has to be tested in long period tests, spanning for several days, as well as in situation of controlled stoppage of operation of freezing borehole, to check if the monitoring system work well in hazardous situation [13].
The most promising data was obtained in a test of vertical seismic profiling. Tests were conducted using device with parameters presented in Table 2. The source of seismic wave was generated on the surface in the near vicinity of a borehole by a 5 kg sledgehammer [13, 17, 18].
Figure 7 presents results of seismic record initial analysis for single measurement in the borehole T1. Traces were filtered in frequency range between 150 and 800 Hz and normalized to common average. Regular amplitudes, effecting from wave propagation, can be observed in the figure.
Figure 7.
Example of seismic record in the borehole T1; vertical axis – Numbers of traces, horizontal axis – Time in ms.
Basing on data obtained from profiling boreholes T1, T2 and T3, a collective map of wave velocity distribution was computed. It is limited to a depth where data obtained is characterized by high quality. Resulting map is shown in Figure 8.
Figure 8.
Map of wave velocity distribution.
There is a relationship between temperature (data collected at the beginning of ground freezing process), presented in Figure 9., and velocity distribution, shown in Figure 10. Data obtained from borehole T1 was chosen for presentation, because of the shortest distance to freezing boreholes.
Figure 9.
Temperature in the borehole T1.
Figure 10.
Velocity in the borehole T1.
Temperature and wave velocity were also compared on one graph, presented in Figure 11. Relationship between them was estimated.
Figure 11.
Relationship between temperature and velocity.
Non-linear, polynomial function with constant parameters was obtained. Function was suited with high correlation factor, equal 0,82. It is clear that there is a relationship between temperature and velocity.
Consequently, graphical correlation of frozen rock mass column development, temperature curve and map of velocity distribution was prepared. It is shown in Figure 12. Blue sections represent temperature and velocity drops, red color indicates temperature and velocity rises. Relationship is clear [13].
Figure 12.
Graphical correlation between velocity distribution, temperature and frozen rock mass cylinder shape.
1,5 months after test described above, another measurements were carried out, within the stage II of the research. Another map of velocity distribution was made. This map, together with the previous one (Figure 9.) are presented in the Figure 13 [18].
Figure 13.
Maps of velocity distribution.
On the basis of conducted research, conclusions were made [13, 18]:
there is a clear relationship between frozen rock mass temperature changes and wave velocity measured. Ground-freezing process monitoring can be conducted using seismic methods.
development of frozen rock mass column is correlated with velocity. It is in stronger relationship with velocity than just temperature, because temperature value only does not give complete information about geomechanical state of rock mass.
relative temperature and velocity changes are complementary. Their correlation might have an impact on rock mass imaging state.
6. Summary
Number of seismic methods can be used for measurements of frozen rock mass parameters, such as frozen ground cylinder shape and size during shaft sinking. However, some of them might be too expensive or problematic in use, not effective enough, etc. Important factor is also time needed for measurements.
Different methods were proposed for the purpose of frozen rock mass column monitoring during Grzegorz shaft sinking. Scattered waves interferometry and vertical seismic profiling were assumed the most convenient.
Seismic interferometry method is favorable because of possibility of conducting near real-time monitoring. High sensitivity for temperature changes can provide accurate indication of failures in freezing installation operation. However, technology of such measurements needs further research, spanning for a long time and covering controlled stoppage of freezing installation operation. Financial aspect of this kind of technology is also an issue to consider.
Vertical seismic profiling provides information about shape and size of frozen ground column. Constant measure is impossible, but periodic measurements might find application, because of possibility of determination of shape of frozen rock mass cylinder for tens of meters forward the shaft heading. Therefore, it helps to forecast potential hazards before the beginning of successive sinking stages. Similar to seismic interferometry method, vertical seismic profiling needs further development and analysis of economic factors. However, this method is considered prospective.
To sum up, geophysical methods of frozen ground column monitoring are prospective direction of research. Technological aspects of these methods should be analyzed and developed to make them economically reasonable.
Acknowledgments
This research received no external funding.
Conflict of interest
The author declares no conflict of interests.
\n',keywords:"mine shaft, ground freezing, mine safety, geophysics measurements, monitoring methods in mining and civil engineering",chapterPDFUrl:"https://cdn.intechopen.com/pdfs/75032.pdf",chapterXML:"https://mts.intechopen.com/source/xml/75032.xml",downloadPdfUrl:"/chapter/pdf-download/75032",previewPdfUrl:"/chapter/pdf-preview/75032",totalDownloads:29,totalViews:0,totalCrossrefCites:0,dateSubmitted:"November 29th 2020",dateReviewed:"January 7th 2021",datePrePublished:"February 1st 2021",datePublished:null,dateFinished:"February 1st 2021",readingETA:"0",abstract:"Grzegorz shaft is the first mine shaft sunk in 21st century in Silesian Coal Basin in USA of ground freezing method. Work carried out by Shaft Sinking Company (PBSz S.A.) is characterized by high level of innovativeness. Geophysical measurements were conducted to find directions of optimization of ground freezing process and its monitoring. Data gathered during research is a starting point for finding directions of optimization of particular fields during Grzegorz shaft sinking, as well as to be used in future similar ventures. Proposed solutions might have bring real improvements for safety and effectiveness of work and also for economic factors. Conducted tests and analysis aim at improvement of monitoring of shape, size and quality of frozen rock mass column in a safe and reliable manner.",reviewType:"peer-reviewed",bibtexUrl:"/chapter/bibtex/75032",risUrl:"/chapter/ris/75032",signatures:"Paweł Kamiński",book:{id:"9965",title:"Computational Optimization Techniques and Applications",subtitle:null,fullTitle:"Computational Optimization Techniques and Applications",slug:null,publishedDate:null,bookSignature:"Prof. Muhammad Sarfraz and Mr. Samsul Ariffin B Abdul Karim",coverURL:"https://cdn.intechopen.com/books/images_new/9965.jpg",licenceType:"CC BY 3.0",editedByType:null,editors:[{id:"215610",title:"Prof.",name:"Muhammad",middleName:null,surname:"Sarfraz",slug:"muhammad-sarfraz",fullName:"Muhammad Sarfraz"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}},authors:null,sections:[{id:"sec_1",title:"1. Introduction. Grzegorz shaft: The first shaft in Silesian Coal Basin sunk using ground freezing method in 21st century",level:"1"},{id:"sec_2",title:"2. Ground freezing method",level:"1"},{id:"sec_3",title:"3. Geological conditions",level:"1"},{id:"sec_3_2",title:"3.1 Geological structure",level:"2"},{id:"sec_4_2",title:"3.2 Hydrogeological conditions",level:"2"},{id:"sec_5_2",title:"3.3 Engineering conditions",level:"2"},{id:"sec_7",title:"4. Freezing installation and boreholes’ construction",level:"1"},{id:"sec_7_2",title:"4.1 Freezing installation",level:"2"},{id:"sec_8_2",title:"4.2 Freezing boreholes",level:"2"},{id:"sec_10",title:"5. Geophysical measurements",level:"1"},{id:"sec_11",title:"6. Summary",level:"1"},{id:"sec_12",title:"Acknowledgments",level:"1"},{id:"sec_15",title:"Conflict of interest",level:"1"}],chapterReferences:[{id:"B1",body:'Jara Ł., Beck M., Drabek J., Kuźma K., Wójcik P., Martyka J., Hajok M., Kamiński P. (2020) Szyb Grzegorz – raport z budowy, Inżynieria Górnicza 1/2020, s. 32-37'},{id:"B2",body:'Izydorczyk P., Kamiński P., Cichoń P. (2018) Szyb Grzegorz – raport z budowy. Wieża wyciągowa oraz górnicze wyciągi szybowe, Inżynieria Górnicza 4/2018, s. 60-62'},{id:"B3",body:'Jara Ł., Beck M., Kamiński P. (2018) Szyb Grzegorz – raport z budowy. Instalacja mrożeniowa, Inżynieria Górnicza 2-3/2018, s. 47-49'},{id:"B4",body:'Kostrz J. (1964) Głębienie szybów metodami specjalnymi, Wydawnictwo „Śląsk”, Katowice 1964'},{id:"B5",body:'Kostrz J. (2014) Głębienie szybów, Biblioteka Szkoły Eksploatacji Podziemnej, Kraków, 2014'},{id:"B6",body:'Harris J.S. (1995) Ground Freezing in Practice. DOI:10.1016/0148-9062(96)91728-3'},{id:"B7",body:'Więckowski A., Hajto D., Proficz P. (2018) Technika zamrażania gruntów i skał luźnych, Przegląd budowlany, 3/2018, PZITB Warszawa'},{id:"B8",body:'Alzoubi M.A., Xu M., Hassani F., Poncet S., & Sasmito A. (2020). Artificial ground freezing: A review of thermal and hydraulic aspects. Tunnelling and Underground Space Technology, 104, 103534'},{id:"B9",body:'Schmall P., Braun B. (2006). Ground Freezing — A Viable and Versatile Construction Technique. Proceedings of the International Conference on Cold Regions Engineering. 1-11. 10.1061/40836(210)29'},{id:"B10",body:'Sanger, F.J. (1968). Ground Freezing in Construction. Journal of the Soil Mechanics and Foundations Division, 94, 131-158'},{id:"B11",body:'Williams P. (2005). Frozen Ground Engineering (Second edition). Chichester: John Wiley & Sons. xii 363 p, illustrated, hard cover. ISBN 0-471-61549-8. Polar Record, 41(2), 174-175. doi:10.1017/S003224740529441X'},{id:"B12",body:'Owczarek D., Wójcik P. (2019) Wiercenie otworów mrożeniowych, In: Proceedings of the International Mining Forum 2019, 11-12.04.2019, Katowice, Poland'},{id:"B13",body:'Matuła R., Czarny R. (2019) Raport. Wyniki zastosowania metod sejsmicznych podczas drążenia szybu Grzegorz. Etap I, praca niepublikowana'},{id:"B14",body:'Sato H., Fehler M.C., Maeda T. (2012) Seismic Wave Propagation and Scattering in the Heterogeneous Earth: Second Edition. Vol 9783642230.; 2012'},{id:"B15",body:'Snieder R., Gret A., Douma H., Scales J. (2002) Coda Wave Interferometry for in Seismic Velocity. Science (80) ;295(March):2253-2255'},{id:"B16",body:'Czarny R. (2017). Ocena budowy i właściwości sprężystych górotworu metodą interferometrii sejsmicznej, PhD dissertation, IGSMiE, AGH University of Science and Technology, Kraków'},{id:"B17",body:'Buske S., Gutjahr S., Sick C. (2009). Fresnel volume migration of single-component seismic data. Geophysics, 74(6, S), WCA47-WCA55'},{id:"B18",body:'Matuła R. (2019) Raport. Wykorzystanie metod sejsmicznych podczas drążenia szybu Grzegorz. Etap II, praca niepublikowana'}],footnotes:[],contributors:[{corresp:"yes",contributorFullName:"Paweł Kamiński",address:"pkamin@agh.edu.pl",affiliation:'
Faculty of Mining and Geoengineering, AGH University of Science and Technology, Krakow, Poland
'}],corrections:null},book:{id:"9965",title:"Computational Optimization Techniques and Applications",subtitle:null,fullTitle:"Computational Optimization Techniques and Applications",slug:null,publishedDate:null,bookSignature:"Prof. Muhammad Sarfraz and Mr. Samsul Ariffin B Abdul Karim",coverURL:"https://cdn.intechopen.com/books/images_new/9965.jpg",licenceType:"CC BY 3.0",editedByType:null,editors:[{id:"215610",title:"Prof.",name:"Muhammad",middleName:null,surname:"Sarfraz",slug:"muhammad-sarfraz",fullName:"Muhammad Sarfraz"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}}},profile:{item:{id:"286369",title:"Dr.",name:"Abdulkareem",middleName:null,surname:"Shehab Diab",email:"dr.kariem2006@yahoo.com",fullName:"Abdulkareem Shehab Diab",slug:"abdulkareem-shehab-diab",position:null,biography:null,institutionString:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",totalCites:0,totalChapterViews:"0",outsideEditionCount:0,totalAuthoredChapters:"1",totalEditedBooks:"0",personalWebsiteURL:null,twitterURL:null,linkedinURL:null,institution:null},booksEdited:[],chaptersAuthored:[{title:"Antioxidant Categories and Mode of Action",slug:"antioxidant-categories-and-mode-of-action",abstract:"Oxidative stress has received a considerable scientific attention as a mediator in the etiology of many human diseases. Oxidative stress is the result of an imbalance between free radicals and antioxidants. Cells can be damaged by free radicals that are considered to play a main role in the aging process and diseases development. Antioxidants are the first line of defense against the detrimental effects of free radical damage, and it is essential to maintain optimal health via different mechanisms of action. Types of antioxidants range from those generated endogenously by the body cells, to exogenous agents such as dietary supplements. Antioxidant insufficiency can be developed as a result of decreased antioxidant intake, synthesis of endogenous enzymes, or increased antioxidant utilization. To maintain optimal body function, antioxidant supplementation has become an increasingly popular practice through improving free radical protection. In this chapter, we first elucidate the oxidative stress, and then define the antioxidant and its categories. Finally, introduce the antioxidants mode of actions for cell protection from free radicals.",signatures:"Manal Azat Aziz, Abdulkareem Shehab Diab and Abeer Abdulrazak Mohammed",authors:[{id:"276717",title:"Associate Prof.",name:"Manal",surname:"Azat Aziz",fullName:"Manal Azat Aziz",slug:"manal-azat-aziz",email:"manalbazaz@yahoo.com"},{id:"286369",title:"Dr.",name:"Abdulkareem",surname:"Shehab Diab",fullName:"Abdulkareem Shehab Diab",slug:"abdulkareem-shehab-diab",email:"dr.kariem2006@yahoo.com"},{id:"312155",title:"Dr.",name:"Abeer Abdulrazak",surname:"Mohammed",fullName:"Abeer Abdulrazak Mohammed",slug:"abeer-abdulrazak-mohammed",email:"abemoh777@gmail.com"}],book:{title:"Antioxidants",slug:"antioxidants",productType:{id:"1",title:"Edited Volume"}}}],collaborators:[{id:"154732",title:"Dr.",name:"Jorge A.",surname:"Mendoza-Pérez",slug:"jorge-a.-mendoza-perez",fullName:"Jorge A. Mendoza-Pérez",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"154908",title:"Dr.",name:"Tomás A.",surname:"Fregoso-Aguilar",slug:"tomas-a.-fregoso-aguilar",fullName:"Tomás A. Fregoso-Aguilar",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"272889",title:"Dr.",name:"Narendra",surname:"Maddu",slug:"narendra-maddu",fullName:"Narendra Maddu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/272889/images/10758_n.jpg",biography:null,institutionString:null,institution:null},{id:"273582",title:"Dr.",name:"Sergio O.",surname:"Flores-Valle",slug:"sergio-o.-flores-valle",fullName:"Sergio O. Flores-Valle",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"276717",title:"Associate Prof.",name:"Manal",surname:"Azat Aziz",slug:"manal-azat-aziz",fullName:"Manal Azat Aziz",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"277367",title:"M.Sc.",name:"Daniel Martin",surname:"Márquez López",slug:"daniel-martin-marquez-lopez",fullName:"Daniel Martin Márquez López",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/277367/images/7909_n.jpg",biography:"Msc Daniel Martin Márquez López has a bachelor degree in Industrial Chemical Engineering, a Master of science degree in the same área and he is a PhD candidate for the Instituto Politécnico Nacional. His Works are realted to the Green chemistry field, biolubricants, biodiesel, transesterification reactions for biodiesel production and the manipulation of oils for therapeutic purposes.",institutionString:null,institution:{name:"Instituto Politécnico Nacional",institutionURL:null,country:{name:"Mexico"}}},{id:"279139",title:"Prof.",name:"Vadim A.",surname:"Kosolapov",slug:"vadim-a.-kosolapov",fullName:"Vadim A. Kosolapov",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"286027",title:"Prof.",name:"Alexander",surname:"Spasov",slug:"alexander-spasov",fullName:"Alexander Spasov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/no_image.jpg",biography:null,institutionString:null,institution:{name:"Volgograd State Medical University",institutionURL:null,country:{name:"Russia"}}},{id:"286031",title:"Prof.",name:"Olga N.",surname:"Zhukovskaya",slug:"olga-n.-zhukovskaya",fullName:"Olga N. Zhukovskaya",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"286074",title:"Prof.",name:"Vera A.",surname:"Anisimova",slug:"vera-a.-anisimova",fullName:"Vera A. Anisimova",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null}]},generic:{page:{slug:"open-access-funding-funders-list",title:"List of Funders by Country",intro:"
If your research is financed through any of the below-mentioned funders, please consult their Open Access policies or grant ‘terms and conditions’ to explore ways to cover your publication costs (also accessible by clicking on the link in their title).
\n\n
IMPORTANT: You must be a member or grantee of the listed funders in order to apply for their Open Access publication funds. Do not attempt to contact the funders if this is not the case.
",metaTitle:"List of Funders by Country",metaDescription:"If your research is financed through any of the below-mentioned funders, please consult their Open Access policies or grant ‘terms and conditions’ to explore ways to cover your publication costs (also accessible by clicking on the link in their title).",metaKeywords:null,canonicalURL:"/page/open-access-funding-funders-list",contentRaw:'[{"type":"htmlEditorComponent","content":"
UK Research and Innovation (former Research Councils UK (RCUK) - including AHRC, BBSRC, ESRC, EPSRC, MRC, NERC, STFC.) Processing charges for books/book chapters can be covered through RCUK block grants which are allocated to most universities in the UK, which then handle the OA publication funding requests. It is at the discretion of the university whether it will approve the request.)
UK Research and Innovation (former Research Councils UK (RCUK) - including AHRC, BBSRC, ESRC, EPSRC, MRC, NERC, STFC.) Processing charges for books/book chapters can be covered through RCUK block grants which are allocated to most universities in the UK, which then handle the OA publication funding requests. It is at the discretion of the university whether it will approve the request.)
Wellcome Trust (Funding available only to Wellcome-funded researchers/grantees)
\n
\n'}]},successStories:{items:[]},authorsAndEditors:{filterParams:{sort:"featured,name"},profiles:[{id:"6700",title:"Dr.",name:"Abbass A.",middleName:null,surname:"Hashim",slug:"abbass-a.-hashim",fullName:"Abbass A. Hashim",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/6700/images/1864_n.jpg",biography:"Currently I am carrying out research in several areas of interest, mainly covering work on chemical and bio-sensors, semiconductor thin film device fabrication and characterisation.\nAt the moment I have very strong interest in radiation environmental pollution and bacteriology treatment. The teams of researchers are working very hard to bring novel results in this field. I am also a member of the team in charge for the supervision of Ph.D. students in the fields of development of silicon based planar waveguide sensor devices, study of inelastic electron tunnelling in planar tunnelling nanostructures for sensing applications and development of organotellurium(IV) compounds for semiconductor applications. I am a specialist in data analysis techniques and nanosurface structure. I have served as the editor for many books, been a member of the editorial board in science journals, have published many papers and hold many patents.",institutionString:null,institution:{name:"Sheffield Hallam University",country:{name:"United Kingdom"}}},{id:"54525",title:"Prof.",name:"Abdul Latif",middleName:null,surname:"Ahmad",slug:"abdul-latif-ahmad",fullName:"Abdul Latif Ahmad",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"20567",title:"Prof.",name:"Ado",middleName:null,surname:"Jorio",slug:"ado-jorio",fullName:"Ado Jorio",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Universidade Federal de Minas Gerais",country:{name:"Brazil"}}},{id:"47940",title:"Dr.",name:"Alberto",middleName:null,surname:"Mantovani",slug:"alberto-mantovani",fullName:"Alberto Mantovani",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"12392",title:"Mr.",name:"Alex",middleName:null,surname:"Lazinica",slug:"alex-lazinica",fullName:"Alex Lazinica",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/12392/images/7282_n.png",biography:"Alex Lazinica is the founder and CEO of IntechOpen. After obtaining a Master's degree in Mechanical Engineering, he continued his PhD studies in Robotics at the Vienna University of Technology. Here he worked as a robotic researcher with the university's Intelligent Manufacturing Systems Group as well as a guest researcher at various European universities, including the Swiss Federal Institute of Technology Lausanne (EPFL). During this time he published more than 20 scientific papers, gave presentations, served as a reviewer for major robotic journals and conferences and most importantly he co-founded and built the International Journal of Advanced Robotic Systems- world's first Open Access journal in the field of robotics. Starting this journal was a pivotal point in his career, since it was a pathway to founding IntechOpen - Open Access publisher focused on addressing academic researchers needs. Alex is a personification of IntechOpen key values being trusted, open and entrepreneurial. Today his focus is on defining the growth and development strategy for the company.",institutionString:null,institution:{name:"TU Wien",country:{name:"Austria"}}},{id:"19816",title:"Prof.",name:"Alexander",middleName:null,surname:"Kokorin",slug:"alexander-kokorin",fullName:"Alexander Kokorin",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/19816/images/1607_n.jpg",biography:"Alexander I. Kokorin: born: 1947, Moscow; DSc., PhD; Principal Research Fellow (Research Professor) of Department of Kinetics and Catalysis, N. Semenov Institute of Chemical Physics, Russian Academy of Sciences, Moscow.\r\nArea of research interests: physical chemistry of complex-organized molecular and nanosized systems, including polymer-metal complexes; the surface of doped oxide semiconductors. He is an expert in structural, absorptive, catalytic and photocatalytic properties, in structural organization and dynamic features of ionic liquids, in magnetic interactions between paramagnetic centers. The author or co-author of 3 books, over 200 articles and reviews in scientific journals and books. He is an actual member of the International EPR/ESR Society, European Society on Quantum Solar Energy Conversion, Moscow House of Scientists, of the Board of Moscow Physical Society.",institutionString:null,institution:{name:"Semenov Institute of Chemical Physics",country:{name:"Russia"}}},{id:"62389",title:"PhD.",name:"Ali Demir",middleName:null,surname:"Sezer",slug:"ali-demir-sezer",fullName:"Ali Demir Sezer",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/62389/images/3413_n.jpg",biography:"Dr. Ali Demir Sezer has a Ph.D. from Pharmaceutical Biotechnology at the Faculty of Pharmacy, University of Marmara (Turkey). He is the member of many Pharmaceutical Associations and acts as a reviewer of scientific journals and European projects under different research areas such as: drug delivery systems, nanotechnology and pharmaceutical biotechnology. Dr. Sezer is the author of many scientific publications in peer-reviewed journals and poster communications. Focus of his research activity is drug delivery, physico-chemical characterization and biological evaluation of biopolymers micro and nanoparticles as modified drug delivery system, and colloidal drug carriers (liposomes, nanoparticles etc.).",institutionString:null,institution:{name:"Marmara University",country:{name:"Turkey"}}},{id:"61051",title:"Prof.",name:"Andrea",middleName:null,surname:"Natale",slug:"andrea-natale",fullName:"Andrea Natale",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"100762",title:"Prof.",name:"Andrea",middleName:null,surname:"Natale",slug:"andrea-natale",fullName:"Andrea Natale",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"St David's Medical Center",country:{name:"United States of America"}}},{id:"107416",title:"Dr.",name:"Andrea",middleName:null,surname:"Natale",slug:"andrea-natale",fullName:"Andrea Natale",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Texas Cardiac Arrhythmia",country:{name:"United States of America"}}},{id:"64434",title:"Dr.",name:"Angkoon",middleName:null,surname:"Phinyomark",slug:"angkoon-phinyomark",fullName:"Angkoon Phinyomark",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/64434/images/2619_n.jpg",biography:"My name is Angkoon Phinyomark. I received a B.Eng. degree in Computer Engineering with First Class Honors in 2008 from Prince of Songkla University, Songkhla, Thailand, where I received a Ph.D. degree in Electrical Engineering. My research interests are primarily in the area of biomedical signal processing and classification notably EMG (electromyography signal), EOG (electrooculography signal), and EEG (electroencephalography signal), image analysis notably breast cancer analysis and optical coherence tomography, and rehabilitation engineering. I became a student member of IEEE in 2008. During October 2011-March 2012, I had worked at School of Computer Science and Electronic Engineering, University of Essex, Colchester, Essex, United Kingdom. In addition, during a B.Eng. I had been a visiting research student at Faculty of Computer Science, University of Murcia, Murcia, Spain for three months.\n\nI have published over 40 papers during 5 years in refereed journals, books, and conference proceedings in the areas of electro-physiological signals processing and classification, notably EMG and EOG signals, fractal analysis, wavelet analysis, texture analysis, feature extraction and machine learning algorithms, and assistive and rehabilitative devices. I have several computer programming language certificates, i.e. Sun Certified Programmer for the Java 2 Platform 1.4 (SCJP), Microsoft Certified Professional Developer, Web Developer (MCPD), Microsoft Certified Technology Specialist, .NET Framework 2.0 Web (MCTS). I am a Reviewer for several refereed journals and international conferences, such as IEEE Transactions on Biomedical Engineering, IEEE Transactions on Industrial Electronics, Optic Letters, Measurement Science Review, and also a member of the International Advisory Committee for 2012 IEEE Business Engineering and Industrial Applications and 2012 IEEE Symposium on Business, Engineering and Industrial Applications.",institutionString:null,institution:{name:"Joseph Fourier University",country:{name:"France"}}},{id:"55578",title:"Dr.",name:"Antonio",middleName:null,surname:"Jurado-Navas",slug:"antonio-jurado-navas",fullName:"Antonio Jurado-Navas",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/55578/images/4574_n.png",biography:"Antonio Jurado-Navas received the M.S. degree (2002) and the Ph.D. degree (2009) in Telecommunication Engineering, both from the University of Málaga (Spain). He first worked as a consultant at Vodafone-Spain. From 2004 to 2011, he was a Research Assistant with the Communications Engineering Department at the University of Málaga. In 2011, he became an Assistant Professor in the same department. From 2012 to 2015, he was with Ericsson Spain, where he was working on geo-location\ntools for third generation mobile networks. Since 2015, he is a Marie-Curie fellow at the Denmark Technical University. His current research interests include the areas of mobile communication systems and channel modeling in addition to atmospheric optical communications, adaptive optics and statistics",institutionString:null,institution:{name:"University of Malaga",country:{name:"Spain"}}}],filtersByRegion:[{group:"region",caption:"North America",value:1,count:5766},{group:"region",caption:"Middle and South America",value:2,count:5227},{group:"region",caption:"Africa",value:3,count:1717},{group:"region",caption:"Asia",value:4,count:10367},{group:"region",caption:"Australia and Oceania",value:5,count:897},{group:"region",caption:"Europe",value:6,count:15790}],offset:12,limit:12,total:118189},chapterEmbeded:{data:{}},editorApplication:{success:null,errors:{}},ofsBooks:{filterParams:{sort:"dateEndThirdStepPublish"},books:[{type:"book",id:"6216",title:"Complexity in Biological and Physical Systems",subtitle:"Bifurcations, Solitons and Fractals",isOpenForSubmission:!0,hash:"c511a26efc1b9c0638c8f9244240cb93",slug:"complexity-in-biological-and-physical-systems-bifurcations-solitons-and-fractals",bookSignature:"Ricardo López-Ruiz",coverURL:"https://cdn.intechopen.com/books/images_new/6216.jpg",editedByType:"Edited by",editors:[{id:"9849",title:"Prof.",name:"Ricardo",surname:"Lopez-Ruiz",slug:"ricardo-lopez-ruiz",fullName:"Ricardo Lopez-Ruiz"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10178",title:"Environmental Emissions",subtitle:null,isOpenForSubmission:!0,hash:"febf21ec717bfe20ae25a9dab9b5d438",slug:"environmental-emissions",bookSignature:"Richard Viskup",coverURL:"https://cdn.intechopen.com/books/images_new/10178.jpg",editedByType:"Edited by",editors:[{id:"103742",title:"Dr.",name:"Richard",surname:"Viskup",slug:"richard-viskup",fullName:"Richard Viskup"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10231",title:"Proton Therapy",subtitle:null,isOpenForSubmission:!0,hash:"f4a9009287953c8d1d89f0fa9b7597b0",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/10231.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10652",title:"Visual Object Tracking",subtitle:null,isOpenForSubmission:!0,hash:"96f3ee634a7ba49fa195e50475412af4",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/10652.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10653",title:"Optimization Algorithms",subtitle:null,isOpenForSubmission:!0,hash:"753812dbb9a6f6b57645431063114f6c",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/10653.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10655",title:"Motion Planning",subtitle:null,isOpenForSubmission:!0,hash:"809b5e290cf2dade9e7e0a5ae0ef3df0",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/10655.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10657",title:"Service Robots",subtitle:null,isOpenForSubmission:!0,hash:"5f81b9eea6eb3f9af984031b7af35588",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/10657.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10662",title:"Pedagogy",subtitle:null,isOpenForSubmission:!0,hash:"c858e1c6fb878d3b895acbacec624576",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/10662.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10673",title:"The Psychology of Trust",subtitle:null,isOpenForSubmission:!0,hash:"1f6cac41fd145f718ac0866264499cc8",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/10673.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10675",title:"Hydrostatics",subtitle:null,isOpenForSubmission:!0,hash:"c86c2fa9f835d4ad5e7efd8b01921866",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/10675.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10677",title:"Topology",subtitle:null,isOpenForSubmission:!0,hash:"85eac84b173d785f989522397616124e",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/10677.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10678",title:"Biostatistics",subtitle:null,isOpenForSubmission:!0,hash:"f63db439474a574454a66894db8b394c",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/10678.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],filtersByTopic:[{group:"topic",caption:"Agricultural and Biological Sciences",value:5,count:15},{group:"topic",caption:"Biochemistry, Genetics and Molecular Biology",value:6,count:3},{group:"topic",caption:"Business, Management and Economics",value:7,count:1},{group:"topic",caption:"Chemistry",value:8,count:7},{group:"topic",caption:"Computer and Information Science",value:9,count:6},{group:"topic",caption:"Earth and Planetary Sciences",value:10,count:7},{group:"topic",caption:"Engineering",value:11,count:15},{group:"topic",caption:"Environmental Sciences",value:12,count:2},{group:"topic",caption:"Immunology and Microbiology",value:13,count:3},{group:"topic",caption:"Materials Science",value:14,count:5},{group:"topic",caption:"Mathematics",value:15,count:1},{group:"topic",caption:"Medicine",value:16,count:26},{group:"topic",caption:"Neuroscience",value:18,count:1},{group:"topic",caption:"Pharmacology, Toxicology and Pharmaceutical Science",value:19,count:2},{group:"topic",caption:"Physics",value:20,count:2},{group:"topic",caption:"Psychology",value:21,count:4},{group:"topic",caption:"Social Sciences",value:23,count:2},{group:"topic",caption:"Technology",value:24,count:1},{group:"topic",caption:"Veterinary Medicine and Science",value:25,count:1},{group:"topic",caption:"Environmental Pollution",value:133,count:1},{group:"topic",caption:"Dynamical Systems Theory",value:966,count:1}],offset:12,limit:12,total:192},popularBooks:{featuredBooks:[{type:"book",id:"9385",title:"Renewable Energy",subtitle:"Technologies and Applications",isOpenForSubmission:!1,hash:"a6b446d19166f17f313008e6c056f3d8",slug:"renewable-energy-technologies-and-applications",bookSignature:"Tolga Taner, Archana Tiwari and Taha Selim Ustun",coverURL:"https://cdn.intechopen.com/books/images_new/9385.jpg",editors:[{id:"197240",title:"Associate Prof.",name:"Tolga",middleName:null,surname:"Taner",slug:"tolga-taner",fullName:"Tolga Taner"}],equalEditorOne:{id:"186791",title:"Dr.",name:"Archana",middleName:null,surname:"Tiwari",slug:"archana-tiwari",fullName:"Archana Tiwari",profilePictureURL:"https://mts.intechopen.com/storage/users/186791/images/system/186791.jpg",biography:"Dr. Archana Tiwari is Associate Professor at Amity University, India. Her research interests include renewable sources of energy from microalgae and further utilizing the residual biomass for the generation of value-added products, bioremediation through microalgae and microbial consortium, antioxidative enzymes and stress, and nutraceuticals from microalgae. She has been working on algal biotechnology for the last two decades. She has published her research in many international journals and has authored many books and chapters with renowned publishing houses. She has also delivered talks as an invited speaker at many national and international conferences. Dr. Tiwari is the recipient of several awards including Researcher of the Year and Distinguished Scientist.",institutionString:"Amity University",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"3",totalChapterViews:"0",totalEditedBooks:"1",institution:{name:"Amity University",institutionURL:null,country:{name:"India"}}},equalEditorTwo:{id:"197609",title:"Prof.",name:"Taha Selim",middleName:null,surname:"Ustun",slug:"taha-selim-ustun",fullName:"Taha Selim Ustun",profilePictureURL:"https://mts.intechopen.com/storage/users/197609/images/system/197609.jpeg",biography:"Dr. Taha Selim Ustun received a Ph.D. in Electrical Engineering from Victoria University, Melbourne, Australia. He is a researcher with the Fukushima Renewable Energy Institute, AIST (FREA), where he leads the Smart Grid Cybersecurity Laboratory. Prior to that, he was a faculty member with the School of Electrical and Computer Engineering, Carnegie Mellon University, Pittsburgh, PA, USA. His current research interests include power systems protection, communication in power networks, distributed generation, microgrids, electric vehicle integration, and cybersecurity in smart grids. He serves on the editorial boards of IEEE Access, IEEE Transactions on Industrial Informatics, Energies, Electronics, Electricity, World Electric Vehicle and Information journals. Dr. Ustun is a member of the IEEE 2004 and 2800, IEC Renewable Energy Management WG 8, and IEC TC 57 WG17. He has been invited to run specialist courses in Africa, India, and China. He has delivered talks for the Qatar Foundation, the World Energy Council, the Waterloo Global Science Initiative, and the European Union Energy Initiative (EUEI). His research has attracted funding from prestigious programs in Japan, Australia, the European Union, and North America.",institutionString:"Fukushima Renewable Energy Institute, AIST (FREA)",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"1",totalChapterViews:"0",totalEditedBooks:"0",institution:{name:"National Institute of Advanced Industrial Science and Technology",institutionURL:null,country:{name:"Japan"}}},equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"8985",title:"Natural Resources Management and Biological Sciences",subtitle:null,isOpenForSubmission:!1,hash:"5c2e219a6c021a40b5a20c041dea88c4",slug:"natural-resources-management-and-biological-sciences",bookSignature:"Edward R. Rhodes and Humood Naser",coverURL:"https://cdn.intechopen.com/books/images_new/8985.jpg",editors:[{id:"280886",title:"Prof.",name:"Edward R",middleName:null,surname:"Rhodes",slug:"edward-r-rhodes",fullName:"Edward R Rhodes"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9027",title:"Human Blood Group Systems and Haemoglobinopathies",subtitle:null,isOpenForSubmission:!1,hash:"d00d8e40b11cfb2547d1122866531c7e",slug:"human-blood-group-systems-and-haemoglobinopathies",bookSignature:"Osaro Erhabor and Anjana Munshi",coverURL:"https://cdn.intechopen.com/books/images_new/9027.jpg",editors:[{id:"35140",title:null,name:"Osaro",middleName:null,surname:"Erhabor",slug:"osaro-erhabor",fullName:"Osaro Erhabor"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"7841",title:"New Insights Into Metabolic Syndrome",subtitle:null,isOpenForSubmission:!1,hash:"ef5accfac9772b9e2c9eff884f085510",slug:"new-insights-into-metabolic-syndrome",bookSignature:"Akikazu Takada",coverURL:"https://cdn.intechopen.com/books/images_new/7841.jpg",editors:[{id:"248459",title:"Dr.",name:"Akikazu",middleName:null,surname:"Takada",slug:"akikazu-takada",fullName:"Akikazu Takada"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"8558",title:"Aerodynamics",subtitle:null,isOpenForSubmission:!1,hash:"db7263fc198dfb539073ba0260a7f1aa",slug:"aerodynamics",bookSignature:"Mofid Gorji-Bandpy and Aly-Mousaad Aly",coverURL:"https://cdn.intechopen.com/books/images_new/8558.jpg",editors:[{id:"35542",title:"Prof.",name:"Mofid",middleName:null,surname:"Gorji-Bandpy",slug:"mofid-gorji-bandpy",fullName:"Mofid Gorji-Bandpy"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9668",title:"Chemistry and Biochemistry of Winemaking, Wine Stabilization and Aging",subtitle:null,isOpenForSubmission:!1,hash:"c5484276a314628acf21ec1bdc3a86b9",slug:"chemistry-and-biochemistry-of-winemaking-wine-stabilization-and-aging",bookSignature:"Fernanda Cosme, Fernando M. Nunes and Luís Filipe-Ribeiro",coverURL:"https://cdn.intechopen.com/books/images_new/9668.jpg",editors:[{id:"186819",title:"Prof.",name:"Fernanda",middleName:null,surname:"Cosme",slug:"fernanda-cosme",fullName:"Fernanda Cosme"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"7847",title:"Medical Toxicology",subtitle:null,isOpenForSubmission:!1,hash:"db9b65bea093de17a0855a1b27046247",slug:"medical-toxicology",bookSignature:"Pınar Erkekoglu and Tomohisa Ogawa",coverURL:"https://cdn.intechopen.com/books/images_new/7847.jpg",editors:[{id:"109978",title:"Prof.",name:"Pınar",middleName:null,surname:"Erkekoglu",slug:"pinar-erkekoglu",fullName:"Pınar Erkekoglu"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"8620",title:"Mining Techniques",subtitle:"Past, Present and Future",isOpenForSubmission:!1,hash:"b65658f81d14e9e57e49377869d3a575",slug:"mining-techniques-past-present-and-future",bookSignature:"Abhay Soni",coverURL:"https://cdn.intechopen.com/books/images_new/8620.jpg",editors:[{id:"271093",title:"Dr.",name:"Abhay",middleName:null,surname:"Soni",slug:"abhay-soni",fullName:"Abhay Soni"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9660",title:"Inland Waters",subtitle:"Dynamics and Ecology",isOpenForSubmission:!1,hash:"975c26819ceb11a926793bc2adc62bd6",slug:"inland-waters-dynamics-and-ecology",bookSignature:"Adam Devlin, Jiayi Pan and Mohammad Manjur Shah",coverURL:"https://cdn.intechopen.com/books/images_new/9660.jpg",editors:[{id:"280757",title:"Dr.",name:"Adam",middleName:"Thomas",surname:"Devlin",slug:"adam-devlin",fullName:"Adam Devlin"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9122",title:"Cosmetic Surgery",subtitle:null,isOpenForSubmission:!1,hash:"207026ca4a4125e17038e770d00ee152",slug:"cosmetic-surgery",bookSignature:"Yueh-Bih Tang",coverURL:"https://cdn.intechopen.com/books/images_new/9122.jpg",editors:[{id:"202122",title:"Prof.",name:"Yueh-Bih",middleName:null,surname:"Tang",slug:"yueh-bih-tang",fullName:"Yueh-Bih Tang"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9043",title:"Parenting",subtitle:"Studies by an Ecocultural and Transactional Perspective",isOpenForSubmission:!1,hash:"6d21066c7438e459e4c6fb13217a5c8c",slug:"parenting-studies-by-an-ecocultural-and-transactional-perspective",bookSignature:"Loredana Benedetto and Massimo Ingrassia",coverURL:"https://cdn.intechopen.com/books/images_new/9043.jpg",editors:[{id:"193200",title:"Prof.",name:"Loredana",middleName:null,surname:"Benedetto",slug:"loredana-benedetto",fullName:"Loredana Benedetto"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9731",title:"Oxidoreductase",subtitle:null,isOpenForSubmission:!1,hash:"852e6f862c85fc3adecdbaf822e64e6e",slug:"oxidoreductase",bookSignature:"Mahmoud Ahmed Mansour",coverURL:"https://cdn.intechopen.com/books/images_new/9731.jpg",editors:[{id:"224662",title:"Prof.",name:"Mahmoud Ahmed",middleName:null,surname:"Mansour",slug:"mahmoud-ahmed-mansour",fullName:"Mahmoud Ahmed Mansour"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}}],offset:12,limit:12,total:5227},hotBookTopics:{hotBooks:[],offset:0,limit:12,total:null},publish:{},publishingProposal:{success:null,errors:{}},books:{featuredBooks:[{type:"book",id:"9385",title:"Renewable Energy",subtitle:"Technologies and Applications",isOpenForSubmission:!1,hash:"a6b446d19166f17f313008e6c056f3d8",slug:"renewable-energy-technologies-and-applications",bookSignature:"Tolga Taner, Archana Tiwari and Taha Selim Ustun",coverURL:"https://cdn.intechopen.com/books/images_new/9385.jpg",editors:[{id:"197240",title:"Associate Prof.",name:"Tolga",middleName:null,surname:"Taner",slug:"tolga-taner",fullName:"Tolga Taner"}],equalEditorOne:{id:"186791",title:"Dr.",name:"Archana",middleName:null,surname:"Tiwari",slug:"archana-tiwari",fullName:"Archana Tiwari",profilePictureURL:"https://mts.intechopen.com/storage/users/186791/images/system/186791.jpg",biography:"Dr. Archana Tiwari is Associate Professor at Amity University, India. Her research interests include renewable sources of energy from microalgae and further utilizing the residual biomass for the generation of value-added products, bioremediation through microalgae and microbial consortium, antioxidative enzymes and stress, and nutraceuticals from microalgae. She has been working on algal biotechnology for the last two decades. She has published her research in many international journals and has authored many books and chapters with renowned publishing houses. She has also delivered talks as an invited speaker at many national and international conferences. Dr. Tiwari is the recipient of several awards including Researcher of the Year and Distinguished Scientist.",institutionString:"Amity University",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"3",totalChapterViews:"0",totalEditedBooks:"1",institution:{name:"Amity University",institutionURL:null,country:{name:"India"}}},equalEditorTwo:{id:"197609",title:"Prof.",name:"Taha Selim",middleName:null,surname:"Ustun",slug:"taha-selim-ustun",fullName:"Taha Selim Ustun",profilePictureURL:"https://mts.intechopen.com/storage/users/197609/images/system/197609.jpeg",biography:"Dr. Taha Selim Ustun received a Ph.D. in Electrical Engineering from Victoria University, Melbourne, Australia. He is a researcher with the Fukushima Renewable Energy Institute, AIST (FREA), where he leads the Smart Grid Cybersecurity Laboratory. Prior to that, he was a faculty member with the School of Electrical and Computer Engineering, Carnegie Mellon University, Pittsburgh, PA, USA. His current research interests include power systems protection, communication in power networks, distributed generation, microgrids, electric vehicle integration, and cybersecurity in smart grids. He serves on the editorial boards of IEEE Access, IEEE Transactions on Industrial Informatics, Energies, Electronics, Electricity, World Electric Vehicle and Information journals. Dr. Ustun is a member of the IEEE 2004 and 2800, IEC Renewable Energy Management WG 8, and IEC TC 57 WG17. He has been invited to run specialist courses in Africa, India, and China. He has delivered talks for the Qatar Foundation, the World Energy Council, the Waterloo Global Science Initiative, and the European Union Energy Initiative (EUEI). His research has attracted funding from prestigious programs in Japan, Australia, the European Union, and North America.",institutionString:"Fukushima Renewable Energy Institute, AIST (FREA)",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"1",totalChapterViews:"0",totalEditedBooks:"0",institution:{name:"National Institute of Advanced Industrial Science and Technology",institutionURL:null,country:{name:"Japan"}}},equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"8985",title:"Natural Resources Management and Biological Sciences",subtitle:null,isOpenForSubmission:!1,hash:"5c2e219a6c021a40b5a20c041dea88c4",slug:"natural-resources-management-and-biological-sciences",bookSignature:"Edward R. Rhodes and Humood Naser",coverURL:"https://cdn.intechopen.com/books/images_new/8985.jpg",editors:[{id:"280886",title:"Prof.",name:"Edward R",middleName:null,surname:"Rhodes",slug:"edward-r-rhodes",fullName:"Edward R Rhodes"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9027",title:"Human Blood Group Systems and Haemoglobinopathies",subtitle:null,isOpenForSubmission:!1,hash:"d00d8e40b11cfb2547d1122866531c7e",slug:"human-blood-group-systems-and-haemoglobinopathies",bookSignature:"Osaro Erhabor and Anjana Munshi",coverURL:"https://cdn.intechopen.com/books/images_new/9027.jpg",editors:[{id:"35140",title:null,name:"Osaro",middleName:null,surname:"Erhabor",slug:"osaro-erhabor",fullName:"Osaro Erhabor"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"7841",title:"New Insights Into Metabolic Syndrome",subtitle:null,isOpenForSubmission:!1,hash:"ef5accfac9772b9e2c9eff884f085510",slug:"new-insights-into-metabolic-syndrome",bookSignature:"Akikazu Takada",coverURL:"https://cdn.intechopen.com/books/images_new/7841.jpg",editors:[{id:"248459",title:"Dr.",name:"Akikazu",middleName:null,surname:"Takada",slug:"akikazu-takada",fullName:"Akikazu Takada"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"8558",title:"Aerodynamics",subtitle:null,isOpenForSubmission:!1,hash:"db7263fc198dfb539073ba0260a7f1aa",slug:"aerodynamics",bookSignature:"Mofid Gorji-Bandpy and Aly-Mousaad Aly",coverURL:"https://cdn.intechopen.com/books/images_new/8558.jpg",editors:[{id:"35542",title:"Prof.",name:"Mofid",middleName:null,surname:"Gorji-Bandpy",slug:"mofid-gorji-bandpy",fullName:"Mofid Gorji-Bandpy"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9668",title:"Chemistry and Biochemistry of Winemaking, Wine Stabilization and Aging",subtitle:null,isOpenForSubmission:!1,hash:"c5484276a314628acf21ec1bdc3a86b9",slug:"chemistry-and-biochemistry-of-winemaking-wine-stabilization-and-aging",bookSignature:"Fernanda Cosme, Fernando M. Nunes and Luís Filipe-Ribeiro",coverURL:"https://cdn.intechopen.com/books/images_new/9668.jpg",editors:[{id:"186819",title:"Prof.",name:"Fernanda",middleName:null,surname:"Cosme",slug:"fernanda-cosme",fullName:"Fernanda Cosme"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"7847",title:"Medical Toxicology",subtitle:null,isOpenForSubmission:!1,hash:"db9b65bea093de17a0855a1b27046247",slug:"medical-toxicology",bookSignature:"Pınar Erkekoglu and Tomohisa Ogawa",coverURL:"https://cdn.intechopen.com/books/images_new/7847.jpg",editors:[{id:"109978",title:"Prof.",name:"Pınar",middleName:null,surname:"Erkekoglu",slug:"pinar-erkekoglu",fullName:"Pınar Erkekoglu"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"8620",title:"Mining Techniques",subtitle:"Past, Present and Future",isOpenForSubmission:!1,hash:"b65658f81d14e9e57e49377869d3a575",slug:"mining-techniques-past-present-and-future",bookSignature:"Abhay Soni",coverURL:"https://cdn.intechopen.com/books/images_new/8620.jpg",editors:[{id:"271093",title:"Dr.",name:"Abhay",middleName:null,surname:"Soni",slug:"abhay-soni",fullName:"Abhay Soni"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9660",title:"Inland Waters",subtitle:"Dynamics and Ecology",isOpenForSubmission:!1,hash:"975c26819ceb11a926793bc2adc62bd6",slug:"inland-waters-dynamics-and-ecology",bookSignature:"Adam Devlin, Jiayi Pan and Mohammad Manjur Shah",coverURL:"https://cdn.intechopen.com/books/images_new/9660.jpg",editors:[{id:"280757",title:"Dr.",name:"Adam",middleName:"Thomas",surname:"Devlin",slug:"adam-devlin",fullName:"Adam Devlin"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9122",title:"Cosmetic Surgery",subtitle:null,isOpenForSubmission:!1,hash:"207026ca4a4125e17038e770d00ee152",slug:"cosmetic-surgery",bookSignature:"Yueh-Bih Tang",coverURL:"https://cdn.intechopen.com/books/images_new/9122.jpg",editors:[{id:"202122",title:"Prof.",name:"Yueh-Bih",middleName:null,surname:"Tang",slug:"yueh-bih-tang",fullName:"Yueh-Bih Tang"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}}],latestBooks:[{type:"book",id:"9550",title:"Entrepreneurship",subtitle:"Contemporary Issues",isOpenForSubmission:!1,hash:"9b4ac1ee5b743abf6f88495452b1e5e7",slug:"entrepreneurship-contemporary-issues",bookSignature:"Mladen Turuk",coverURL:"https://cdn.intechopen.com/books/images_new/9550.jpg",editedByType:"Edited by",editors:[{id:"319755",title:"Prof.",name:"Mladen",middleName:null,surname:"Turuk",slug:"mladen-turuk",fullName:"Mladen Turuk"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10065",title:"Wavelet Theory",subtitle:null,isOpenForSubmission:!1,hash:"d8868e332169597ba2182d9b004d60de",slug:"wavelet-theory",bookSignature:"Somayeh Mohammady",coverURL:"https://cdn.intechopen.com/books/images_new/10065.jpg",editedByType:"Edited by",editors:[{id:"109280",title:"Dr.",name:"Somayeh",middleName:null,surname:"Mohammady",slug:"somayeh-mohammady",fullName:"Somayeh Mohammady"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9313",title:"Clay Science and Technology",subtitle:null,isOpenForSubmission:!1,hash:"6fa7e70396ff10620e032bb6cfa6fb72",slug:"clay-science-and-technology",bookSignature:"Gustavo Morari Do Nascimento",coverURL:"https://cdn.intechopen.com/books/images_new/9313.jpg",editedByType:"Edited by",editors:[{id:"7153",title:"Prof.",name:"Gustavo",middleName:null,surname:"Morari Do Nascimento",slug:"gustavo-morari-do-nascimento",fullName:"Gustavo Morari Do Nascimento"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9888",title:"Nuclear Power Plants",subtitle:"The Processes from the Cradle to the Grave",isOpenForSubmission:!1,hash:"c2c8773e586f62155ab8221ebb72a849",slug:"nuclear-power-plants-the-processes-from-the-cradle-to-the-grave",bookSignature:"Nasser Awwad",coverURL:"https://cdn.intechopen.com/books/images_new/9888.jpg",editedByType:"Edited by",editors:[{id:"145209",title:"Prof.",name:"Nasser",middleName:"S",surname:"Awwad",slug:"nasser-awwad",fullName:"Nasser Awwad"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8098",title:"Resources of Water",subtitle:null,isOpenForSubmission:!1,hash:"d251652996624d932ef7b8ed62cf7cfc",slug:"resources-of-water",bookSignature:"Prathna Thanjavur Chandrasekaran, Muhammad Salik Javaid, Aftab Sadiq",coverURL:"https://cdn.intechopen.com/books/images_new/8098.jpg",editedByType:"Edited by",editors:[{id:"167917",title:"Dr.",name:"Prathna",middleName:null,surname:"Thanjavur Chandrasekaran",slug:"prathna-thanjavur-chandrasekaran",fullName:"Prathna Thanjavur Chandrasekaran"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9644",title:"Glaciers and the Polar Environment",subtitle:null,isOpenForSubmission:!1,hash:"e8cfdc161794e3753ced54e6ff30873b",slug:"glaciers-and-the-polar-environment",bookSignature:"Masaki Kanao, Danilo Godone and Niccolò Dematteis",coverURL:"https://cdn.intechopen.com/books/images_new/9644.jpg",editedByType:"Edited by",editors:[{id:"51959",title:"Dr.",name:"Masaki",middleName:null,surname:"Kanao",slug:"masaki-kanao",fullName:"Masaki Kanao"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10432",title:"Casting Processes and Modelling of Metallic Materials",subtitle:null,isOpenForSubmission:!1,hash:"2c5c9df938666bf5d1797727db203a6d",slug:"casting-processes-and-modelling-of-metallic-materials",bookSignature:"Zakaria Abdallah and Nada Aldoumani",coverURL:"https://cdn.intechopen.com/books/images_new/10432.jpg",editedByType:"Edited by",editors:[{id:"201670",title:"Dr.",name:"Zak",middleName:null,surname:"Abdallah",slug:"zak-abdallah",fullName:"Zak Abdallah"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9671",title:"Macrophages",subtitle:null,isOpenForSubmission:!1,hash:"03b00fdc5f24b71d1ecdfd75076bfde6",slug:"macrophages",bookSignature:"Hridayesh Prakash",coverURL:"https://cdn.intechopen.com/books/images_new/9671.jpg",editedByType:"Edited by",editors:[{id:"287184",title:"Dr.",name:"Hridayesh",middleName:null,surname:"Prakash",slug:"hridayesh-prakash",fullName:"Hridayesh Prakash"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8415",title:"Extremophilic Microbes and Metabolites",subtitle:"Diversity, Bioprospecting and Biotechnological Applications",isOpenForSubmission:!1,hash:"93e0321bc93b89ff73730157738f8f97",slug:"extremophilic-microbes-and-metabolites-diversity-bioprospecting-and-biotechnological-applications",bookSignature:"Afef Najjari, Ameur Cherif, Haïtham Sghaier and Hadda Imene Ouzari",coverURL:"https://cdn.intechopen.com/books/images_new/8415.jpg",editedByType:"Edited by",editors:[{id:"196823",title:"Dr.",name:"Afef",middleName:null,surname:"Najjari",slug:"afef-najjari",fullName:"Afef Najjari"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9731",title:"Oxidoreductase",subtitle:null,isOpenForSubmission:!1,hash:"852e6f862c85fc3adecdbaf822e64e6e",slug:"oxidoreductase",bookSignature:"Mahmoud Ahmed Mansour",coverURL:"https://cdn.intechopen.com/books/images_new/9731.jpg",editedByType:"Edited by",editors:[{id:"224662",title:"Prof.",name:"Mahmoud Ahmed",middleName:null,surname:"Mansour",slug:"mahmoud-ahmed-mansour",fullName:"Mahmoud Ahmed Mansour"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},subject:{topic:{id:"80",title:"Urban Economics",slug:"urban-economics",parent:{title:"Business, Management and Economics",slug:"business-management-and-economics"},numberOfBooks:4,numberOfAuthorsAndEditors:53,numberOfWosCitations:16,numberOfCrossrefCitations:21,numberOfDimensionsCitations:44,videoUrl:null,fallbackUrl:null,description:null},booksByTopicFilter:{topicSlug:"urban-economics",sort:"-publishedDate",limit:12,offset:0},booksByTopicCollection:[{type:"book",id:"7624",title:"Smart Urban Development",subtitle:null,isOpenForSubmission:!1,hash:"455e3fe68e90610076558c6db2a591e1",slug:"smart-urban-development",bookSignature:"Vito Bobek",coverURL:"https://cdn.intechopen.com/books/images_new/7624.jpg",editedByType:"Edited by",editors:[{id:"128342",title:"Prof.",name:"Vito",middleName:null,surname:"Bobek",slug:"vito-bobek",fullName:"Vito Bobek"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9359",title:"Urbanization in Northern Corridor Economic Region in Malaysia",subtitle:null,isOpenForSubmission:!1,hash:"ef5cad7092e96bcfc8de3e1dfae4a5e6",slug:"urbanization-in-northern-corridor-economic-region-in-malaysia",bookSignature:"Noraniza Yusoff",coverURL:"https://cdn.intechopen.com/books/images_new/9359.jpg",editedByType:"Authored by",editors:[{id:"290742",title:"Dr.",name:"Noraniza",middleName:null,surname:"Yusoff",slug:"noraniza-yusoff",fullName:"Noraniza Yusoff"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"4",chapterContentType:"compact",authoredCaption:"Authored by"}},{type:"book",id:"7470",title:"An Overview of Urban and Regional Planning",subtitle:null,isOpenForSubmission:!1,hash:"cf8ba0e06f5b39eebaeb6e0dec33d28e",slug:"an-overview-of-urban-and-regional-planning",bookSignature:"Yasar Bahri Ergen",coverURL:"https://cdn.intechopen.com/books/images_new/7470.jpg",editedByType:"Edited by",editors:[{id:"167276",title:"Associate Prof.",name:"Yasar",middleName:"Bahri",surname:"Ergen",slug:"yasar-ergen",fullName:"Yasar Ergen"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"905",title:"Urban Development",subtitle:null,isOpenForSubmission:!1,hash:"624f51e81d00fc386649ae34890144a4",slug:"urban-development",bookSignature:"Serafeim Polyzos",coverURL:"https://cdn.intechopen.com/books/images_new/905.jpg",editedByType:"Edited by",editors:[{id:"106057",title:"Dr.",name:"Serafeim",middleName:null,surname:"Polyzos",slug:"serafeim-polyzos",fullName:"Serafeim Polyzos"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],booksByTopicTotal:4,mostCitedChapters:[{id:"34598",doi:"10.5772/35133",title:"Reappraising Urban Planning and Urban Sustainability in East Africa",slug:"reappraising-urban-planning-and-urban-sustainability-in-east-africa",totalDownloads:4836,totalCrossrefCites:3,totalDimensionsCites:7,book:{slug:"urban-development",title:"Urban Development",fullTitle:"Urban Development"},signatures:"Shuaib Lwasa and Cecilia Kinuthia-Njenga",authors:[{id:"103098",title:"Dr.",name:"Shuaib",middleName:null,surname:"Lwasa",slug:"shuaib-lwasa",fullName:"Shuaib Lwasa"},{id:"115349",title:"MSc.",name:"Cecilia",middleName:null,surname:"Kinuthia-Njenga",slug:"cecilia-kinuthia-njenga",fullName:"Cecilia Kinuthia-Njenga"}]},{id:"34611",doi:"10.5772/38884",title:"The Evolution and Spatial Dynamics of Coastal Cities in Greece",slug:"the-evolution-and-spatial-dynamics-of-coastal-cities-in-greece",totalDownloads:1601,totalCrossrefCites:1,totalDimensionsCites:6,book:{slug:"urban-development",title:"Urban Development",fullTitle:"Urban Development"},signatures:"Serafeim Polyzos and Dimitrios Tsiotas",authors:[{id:"106057",title:"Dr.",name:"Serafeim",middleName:null,surname:"Polyzos",slug:"serafeim-polyzos",fullName:"Serafeim Polyzos"}]},{id:"34601",doi:"10.5772/37760",title:"Emerging Technologies for Urban Traffic Management",slug:"emerging-technologies-for-urban-traffic-management",totalDownloads:2793,totalCrossrefCites:4,totalDimensionsCites:4,book:{slug:"urban-development",title:"Urban Development",fullTitle:"Urban Development"},signatures:"Antonio Guerrero-Ibanez, Carlos Flores-Cortes, Pedro Damian-Reyes, M. Andrade-Arechiga and J. R. G. Pulido",authors:[{id:"114219",title:"Ph.D.",name:"Juan",middleName:"Antonio",surname:"Guerrero-Ibáñez",slug:"juan-guerrero-ibanez",fullName:"Juan Guerrero-Ibáñez"},{id:"116071",title:"Dr.",name:"Carlos",middleName:null,surname:"Flores-Cortés",slug:"carlos-flores-cortes",fullName:"Carlos Flores-Cortés"},{id:"116072",title:"Dr.",name:"Pedro",middleName:null,surname:"Damián Reyes",slug:"pedro-damian-reyes",fullName:"Pedro Damián Reyes"},{id:"116073",title:"MSc.",name:"María",middleName:null,surname:"Andrade Aréchiga",slug:"maria-andrade-arechiga",fullName:"María Andrade Aréchiga"},{id:"116075",title:"Dr.",name:"Jorge Rafael",middleName:null,surname:"Gutiérrez Pulido",slug:"jorge-rafael-gutierrez-pulido",fullName:"Jorge Rafael Gutiérrez Pulido"}]}],mostDownloadedChaptersLast30Days:[{id:"69772",title:"Smart Rainwater Management: New Technologies and Innovation",slug:"smart-rainwater-management-new-technologies-and-innovation",totalDownloads:820,totalCrossrefCites:0,totalDimensionsCites:1,book:{slug:"smart-urban-development",title:"Smart Urban Development",fullTitle:"Smart Urban Development"},signatures:"Raseswari Pradhan and Jayaprakash Sahoo",authors:null},{id:"63405",title:"Restructuring Gauteng City Region in South Africa: Is a Transportation Solution the Answer?",slug:"restructuring-gauteng-city-region-in-south-africa-is-a-transportation-solution-the-answer-",totalDownloads:1235,totalCrossrefCites:2,totalDimensionsCites:2,book:{slug:"an-overview-of-urban-and-regional-planning",title:"An Overview of Urban and Regional Planning",fullTitle:"An Overview of Urban and Regional Planning"},signatures:"James Chakwizira, Peter Bikam and Thompson A. Adeboyejo",authors:[{id:"250792",title:"Dr.",name:"James",middleName:null,surname:"Chakwizira",slug:"james-chakwizira",fullName:"James Chakwizira"},{id:"265387",title:"Prof.",name:"Peter",middleName:null,surname:"Bikam",slug:"peter-bikam",fullName:"Peter Bikam"},{id:"265388",title:"Prof.",name:"Thompson A",middleName:null,surname:"Adeboyejo",slug:"thompson-a-adeboyejo",fullName:"Thompson A Adeboyejo"}]},{id:"61829",title:"Models of Implementation of Spatial Plans: Theoretical Approach and Case Studies for Spatial Plans for the Special Purpose Area",slug:"models-of-implementation-of-spatial-plans-theoretical-approach-and-case-studies-for-spatial-plans-fo",totalDownloads:932,totalCrossrefCites:1,totalDimensionsCites:1,book:{slug:"an-overview-of-urban-and-regional-planning",title:"An Overview of Urban and Regional Planning",fullTitle:"An Overview of Urban and Regional Planning"},signatures:"Nebojša Stefanović, Boško Josimović and Nataša Danilović Hristić",authors:[{id:"125578",title:"Dr.",name:"Bosko",middleName:null,surname:"Josimovic",slug:"bosko-josimovic",fullName:"Bosko Josimovic"},{id:"249446",title:"Ph.D.",name:"Nebojša",middleName:null,surname:"Stefanović",slug:"nebojsa-stefanovic",fullName:"Nebojša Stefanović"},{id:"255858",title:"Dr.",name:"Nataša",middleName:null,surname:"Dabnilović Hristić",slug:"natasa-dabnilovic-hristic",fullName:"Nataša Dabnilović Hristić"}]},{id:"62114",title:"Urban Noise as an Environmental Impact Factor in the Urban Planning Process",slug:"urban-noise-as-an-environmental-impact-factor-in-the-urban-planning-process",totalDownloads:710,totalCrossrefCites:0,totalDimensionsCites:1,book:{slug:"an-overview-of-urban-and-regional-planning",title:"An Overview of Urban and Regional Planning",fullTitle:"An Overview of Urban and Regional Planning"},signatures:"Elaine Carvalho da Paz, Thomas Jeferson Vieira and Paulo Henrique Trombetta Zannin",authors:[{id:"66572",title:"Prof.",name:"Paulo Henrique Trombetta",middleName:null,surname:"Zannin",slug:"paulo-henrique-trombetta-zannin",fullName:"Paulo Henrique Trombetta Zannin"},{id:"257807",title:"MSc.",name:"Elaine Carvalho",middleName:null,surname:"Da Paz",slug:"elaine-carvalho-da-paz",fullName:"Elaine Carvalho Da Paz"},{id:"257814",title:"Mrs.",name:"Thomas Jeferson",middleName:null,surname:"Vieira",slug:"thomas-jeferson-vieira",fullName:"Thomas Jeferson Vieira"}]},{id:"34607",title:"Istanbul's Backbone - A Chain of Central Business Districts (CBDs)",slug:"istanbul-s-backbone-a-chain-of-cbd-areas",totalDownloads:3064,totalCrossrefCites:0,totalDimensionsCites:2,book:{slug:"urban-development",title:"Urban Development",fullTitle:"Urban Development"},signatures:"Martin Seger",authors:[{id:"108365",title:"Prof.",name:"Martin",middleName:null,surname:"Seger",slug:"martin-seger",fullName:"Martin Seger"}]},{id:"67106",title:"Symmetrical Aspects of Urban Regeneration in Seoul",slug:"symmetrical-aspects-of-urban-regeneration-in-seoul",totalDownloads:316,totalCrossrefCites:0,totalDimensionsCites:0,book:{slug:"smart-urban-development",title:"Smart Urban Development",fullTitle:"Smart Urban Development"},signatures:"Mi-Sun Park, Seunghee Lee and Uk Kim",authors:null},{id:"34598",title:"Reappraising Urban Planning and Urban Sustainability in East Africa",slug:"reappraising-urban-planning-and-urban-sustainability-in-east-africa",totalDownloads:4842,totalCrossrefCites:3,totalDimensionsCites:7,book:{slug:"urban-development",title:"Urban Development",fullTitle:"Urban Development"},signatures:"Shuaib Lwasa and Cecilia Kinuthia-Njenga",authors:[{id:"103098",title:"Dr.",name:"Shuaib",middleName:null,surname:"Lwasa",slug:"shuaib-lwasa",fullName:"Shuaib Lwasa"},{id:"115349",title:"MSc.",name:"Cecilia",middleName:null,surname:"Kinuthia-Njenga",slug:"cecilia-kinuthia-njenga",fullName:"Cecilia Kinuthia-Njenga"}]},{id:"66438",title:"Urbanization in Northern Corridor Economic Region in Malaysia",slug:"urbanization-in-northern-corridor-economic-region-in-malaysia",totalDownloads:625,totalCrossrefCites:0,totalDimensionsCites:0,book:{slug:"urbanization-in-northern-corridor-economic-region-in-malaysia",title:"Urbanization in Northern Corridor Economic Region in Malaysia",fullTitle:"Urbanization in Northern Corridor Economic Region in Malaysia"},signatures:"Noraniza Yusoff",authors:[{id:"290742",title:"Dr.",name:"Noraniza",middleName:null,surname:"Yusoff",slug:"noraniza-yusoff",fullName:"Noraniza Yusoff"}]},{id:"62248",title:"Urban Renewal and Sustainable Development in Jamaica: Progress, Challenges and New Directions",slug:"urban-renewal-and-sustainable-development-in-jamaica-progress-challenges-and-new-directions",totalDownloads:907,totalCrossrefCites:0,totalDimensionsCites:0,book:{slug:"an-overview-of-urban-and-regional-planning",title:"An Overview of Urban and Regional Planning",fullTitle:"An Overview of Urban and Regional Planning"},signatures:"Jasneth Mullings, Leith Dunn, Mona Sue Ho, Rainford Wilks and Carol Archer",authors:[{id:"248594",title:"Ph.D.",name:"Jasneth",middleName:null,surname:"Mullings",slug:"jasneth-mullings",fullName:"Jasneth Mullings"},{id:"258761",title:"Dr.",name:"Leith",middleName:null,surname:"Dunn",slug:"leith-dunn",fullName:"Leith Dunn"},{id:"258762",title:"Mrs.",name:"Mona",middleName:null,surname:"Sue Ho",slug:"mona-sue-ho",fullName:"Mona Sue Ho"},{id:"258763",title:"Prof.",name:"Rainford",middleName:null,surname:"Wilks",slug:"rainford-wilks",fullName:"Rainford Wilks"},{id:"258764",title:"Dr.",name:"Carol",middleName:null,surname:"Archer",slug:"carol-archer",fullName:"Carol Archer"}]},{id:"63048",title:"Absence of Metropolitan Planning Institutes and Territorial Disorganization",slug:"absence-of-metropolitan-planning-institutes-and-territorial-disorganization",totalDownloads:501,totalCrossrefCites:0,totalDimensionsCites:0,book:{slug:"an-overview-of-urban-and-regional-planning",title:"An Overview of Urban and Regional Planning",fullTitle:"An Overview of Urban and Regional Planning"},signatures:"Miguel Etinger de Araujo Junior, Eliane Tomiasi Paulino and Tânia Maria Fresca",authors:[{id:"248195",title:"Dr.",name:"Miguel Etinger",middleName:null,surname:"de Araujo Junior",slug:"miguel-etinger-de-araujo-junior",fullName:"Miguel Etinger de Araujo Junior"},{id:"248913",title:"Dr.",name:"Tania",middleName:null,surname:"Fresca",slug:"tania-fresca",fullName:"Tania Fresca"},{id:"248914",title:"Dr.",name:"Eliane",middleName:null,surname:"Paulino",slug:"eliane-paulino",fullName:"Eliane Paulino"}]}],onlineFirstChaptersFilter:{topicSlug:"urban-economics",limit:3,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[{type:"book",id:"10176",title:"Microgrids and Local Energy Systems",subtitle:null,isOpenForSubmission:!0,hash:"c32b4a5351a88f263074b0d0ca813a9c",slug:null,bookSignature:"Prof. Nick Jenkins",coverURL:"https://cdn.intechopen.com/books/images_new/10176.jpg",editedByType:null,editors:[{id:"55219",title:"Prof.",name:"Nick",middleName:null,surname:"Jenkins",slug:"nick-jenkins",fullName:"Nick Jenkins"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}}],offset:8,limit:8,total:1},route:{name:"onlineFirst.detail",path:"/online-first/optimization-directions-for-monitoring-of-ground-freezing-process-for-grzegorz-shaft-sinking",hash:"",query:{},params:{chapter:"optimization-directions-for-monitoring-of-ground-freezing-process-for-grzegorz-shaft-sinking"},fullPath:"/online-first/optimization-directions-for-monitoring-of-ground-freezing-process-for-grzegorz-shaft-sinking",meta:{},from:{name:null,path:"/",hash:"",query:{},params:{},fullPath:"/",meta:{}}}},function(){var e;(e=document.currentScript||document.scripts[document.scripts.length-1]).parentNode.removeChild(e)}()