\\n\\n
Released this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\\n\\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
\\n"}]',published:!0,mainMedia:{caption:"Highly Cited",originalUrl:"/media/original/117"}},components:[{type:"htmlEditorComponent",content:'IntechOpen is proud to announce that 191 of our authors have made the Clarivate™ Highly Cited Researchers List for 2020, ranking them among the top 1% most-cited.
\n\nThroughout the years, the list has named a total of 261 IntechOpen authors as Highly Cited. Of those researchers, 69 have been featured on the list multiple times.
\n\n\n\nReleased this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\n\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
\n'}],latestNews:[{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"},{slug:"introducing-intechopen-book-series-a-new-publishing-format-for-oa-books-20210915",title:"Introducing IntechOpen Book Series - A New Publishing Format for OA Books"}]},book:{item:{type:"book",id:"7455",leadTitle:null,fullTitle:"Primary Intracranial Tumors",title:"Primary Intracranial Tumors",subtitle:null,reviewType:"peer-reviewed",abstract:"This book covers specific chapters with fundamental and current concepts about the main primary intracranial tumors, aimed at general neurosurgeons, neurologists, oncologists, radiotherapists, and residents. They are everyday situations from the subspecialist routine that can become challenging for professionals outside referenced centers or working alone.",isbn:"978-1-78985-406-0",printIsbn:"978-1-78985-405-3",pdfIsbn:"978-1-83962-080-5",doi:"10.5772/intechopen.75418",price:119,priceEur:129,priceUsd:155,slug:"primary-intracranial-tumors",numberOfPages:140,isOpenForSubmission:!1,isInWos:null,isInBkci:!1,hash:"6b02d6151db3433e9ebc434101c9868b",bookSignature:"Erasmo Barros Da Silva Junior and Jerônimo Buzetti Milano",publishedDate:"March 13th 2019",coverURL:"https://cdn.intechopen.com/books/images_new/7455.jpg",numberOfDownloads:7880,numberOfWosCitations:1,numberOfCrossrefCitations:1,numberOfCrossrefCitationsByBook:0,numberOfDimensionsCitations:2,numberOfDimensionsCitationsByBook:0,hasAltmetrics:1,numberOfTotalCitations:4,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"March 13th 2018",dateEndSecondStepPublish:"April 3rd 2018",dateEndThirdStepPublish:"June 2nd 2018",dateEndFourthStepPublish:"August 21st 2018",dateEndFifthStepPublish:"October 20th 2018",currentStepOfPublishingProcess:5,indexedIn:"1,2,3,4,5,6",editedByType:"Edited by",kuFlag:!1,featuredMarkup:null,editors:[{id:"77927",title:"Dr.",name:"Erasmo Barros",middleName:null,surname:"Da Silva Junior",slug:"erasmo-barros-da-silva-junior",fullName:"Erasmo Barros Da Silva Junior",profilePictureURL:"https://mts.intechopen.com/storage/users/77927/images/6870_n.png",biography:"Dr. Erasmo Barros da Silva Junior is a Medical Graduate from Universidade Federal da Paraíba; he also received neurosurgical training from Neurological Institute of Curitiba, and has a Surgery MSc from Pontifícia Universidade Católica do Paraná. Dr. Erasmo Barros da Silva Junior is member of the Sociedade Brasileira de Neurocirurgia (SBN), Society of Neuro-Oncology, European Association of Neurosurgical Societies (EANS) and Academia Brasileira de Neurocirurgia (ABNC). He is neurosurgeon from Neurological Institute of Curitiba, Neurosurgery department, coordinator of Neurooncology division.",institutionString:null,position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"2",totalChapterViews:"0",totalEditedBooks:"1",institution:{name:"Instituto de Neurologia de Curitiba",institutionURL:null,country:{name:"Brazil"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:{id:"124581",title:"Dr.",name:"Jerônimo",middleName:null,surname:"Buzetti Milano",slug:"jeronimo-buzetti-milano",fullName:"Jerônimo Buzetti Milano",profilePictureURL:"https://mts.intechopen.com/storage/users/124581/images/6871_n.png",biography:"Dr. Jerônimo Buzetti Milano is a Medical Graduate from Universidade Federal do Paraná; he received a neurosurgical training from Neurological Institute of Curitiba, and holds a Neurology PhD from University of São Paulo. Dr. Jerônimo Buzetti Milano is member of the Sociedade Brasileira de Neurocirurgia (SBN), Spine Brazilian Society, North America Spine Society, AOSpine. He is neurosurgeon at Neurological Institute of Curitiba, Neurosurgery department, coordinator of Spine division.",institutionString:null,position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"1",totalChapterViews:"0",totalEditedBooks:"0",institution:null},coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"1085",title:"Neuro-Oncology",slug:"neuro-oncology"}],chapters:[{id:"64575",title:"Atypical and Anaplastic Meningiomas: Diagnosis and Treatment",doi:"10.5772/intechopen.81210",slug:"atypical-and-anaplastic-meningiomas-diagnosis-and-treatment",totalDownloads:912,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"The aim of this chapter is to describe the usefulness of surgical technologies such as neuronavigation, intraoperative MRI, fluorescence-guided surgery and intraoperative monitoring as a tool do make neurosurgical procedures to brain tumors more safe and effective. The main topics to be explored are: history of the specific technique, indications and contra indications, description of the technique, real case examples, pros and cons. The focus on the discussion besides practical aspects is going to be relevant literature regarding impact of their use in avoidance of complications, improve in survival rates, cost-effectiveness, some tips and tricks acquired in the experience of our department.",signatures:"Erasmo Barros da Silva Jr, Gustavo Simiano Jung,\nJoseph Franklin Chenisz da Silva and Ricardo Ramina",downloadPdfUrl:"/chapter/pdf-download/64575",previewPdfUrl:"/chapter/pdf-preview/64575",authors:[{id:"77927",title:"Dr.",name:"Erasmo Barros",surname:"Da Silva Junior",slug:"erasmo-barros-da-silva-junior",fullName:"Erasmo Barros Da Silva Junior"},{id:"46275",title:"Prof.",name:"Ricardo",surname:"Ramina",slug:"ricardo-ramina",fullName:"Ricardo Ramina"},{id:"259905",title:"Dr.",name:"Gustavo",surname:"Jung",slug:"gustavo-jung",fullName:"Gustavo Jung"},{id:"288137",title:"Dr.",name:"Joseph Franklin",surname:"Chenisz Da Silva",slug:"joseph-franklin-chenisz-da-silva",fullName:"Joseph Franklin Chenisz Da Silva"}],corrections:null},{id:"64931",title:"Molecular Diagnostics and Pathology of Major Brain Tumors",doi:"10.5772/intechopen.80856",slug:"molecular-diagnostics-and-pathology-of-major-brain-tumors",totalDownloads:1294,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:1,abstract:"Tumors of central nervous system (CNS) account for a small portion of tumors of human body, which include tumors occurring in the parenchyma of brain and spinal cord as well as their coverings. The following chapter covers some new development in some major brain tumors in both pediatric and adult populations, as well as some uncommon but diagnostic and management challenging tumors.",signatures:"Frank Y. Shan, E. Castro, Amelia Sybenga, Sanjib Mukherjee,\nErxi Wu, Karming Fung, The Li, Ekokobe Fonkem, Jason H. Huang and A. Rao",downloadPdfUrl:"/chapter/pdf-download/64931",previewPdfUrl:"/chapter/pdf-preview/64931",authors:[{id:"31811",title:"Prof.",name:"Renzhi",surname:"Wang",slug:"renzhi-wang",fullName:"Renzhi Wang"},{id:"224305",title:"Dr.",name:"Frank Y.",surname:"Shan",slug:"frank-y.-shan",fullName:"Frank Y. Shan"}],corrections:null},{id:"63710",title:"Potential Use of Long Noncoding RNAs as Biomarkers for Astrocytoma",doi:"10.5772/intechopen.80561",slug:"potential-use-of-long-noncoding-rnas-as-biomarkers-for-astrocytoma",totalDownloads:1120,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Noncoding RNAs represent a high proportion of the human genome and regulate gene expression by means of innumerable and unimaginable modes of action. Particularly, long noncoding RNAs have emerged as central regulators of gene expression and alterations on their function have been associated with many types of cancer, such as astrocytomas. Astrocytomas are the most common type of gliomas in the central nervous system, and glioblastoma multiforme is their most aggressive form. Although adult and pediatric astrocytomas exhibit certain molecular similarities, they are considered as distinct molecular entities. Since to date there is no effective treatments for these tumors, different efforts are being made to find molecular tools useful for this purpose. Studies have shown that both tumor and circulating expression of lncRNAs were altered in astrocytoma, which was useful to distinguish the patients with this neoplasia from those without cancer, as well as to determine different prognostic factors related to the disease. According to these studies, different “molecular signatures” of specific lncRNAs were established, and they have a potential use in the medical practice. From a system biological perspective, complex interaction networks, conformed by lncRNAs, microRNAs, mRNAs, and proteins, were elucidated and predicted to control many oncogenic processes.",signatures:"Ruth Ruiz Esparza-Garrido, Alicia Siordia-Reyes, Gerardo Sánchez,\nGriselda Ramírez and Miguel Velázquez-Flores",downloadPdfUrl:"/chapter/pdf-download/63710",previewPdfUrl:"/chapter/pdf-preview/63710",authors:[{id:"250070",title:"Dr.",name:"Miguel",surname:"Velázquez",slug:"miguel-velazquez",fullName:"Miguel Velázquez"},{id:"258220",title:"Dr.",name:"Ruth",surname:"Ruiz Esparza",slug:"ruth-ruiz-esparza",fullName:"Ruth Ruiz Esparza"},{id:"258501",title:"Dr.",name:"Alicia",surname:"Siordia",slug:"alicia-siordia",fullName:"Alicia Siordia"},{id:"258725",title:"Dr.",name:"Griselda",surname:"Ramírez",slug:"griselda-ramirez",fullName:"Griselda Ramírez"},{id:"258726",title:"Dr.",name:"Gerardo",surname:"Sánchez",slug:"gerardo-sanchez",fullName:"Gerardo Sánchez"}],corrections:null},{id:"63881",title:"Neurosurgical Tools to Improve Safety and Survival in Patients with Intracranial Tumors: Neuronavigation, MRI, and 5-ALA",doi:"10.5772/intechopen.81211",slug:"neurosurgical-tools-to-improve-safety-and-survival-in-patients-with-intracranial-tumors-neuronavigat",totalDownloads:792,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:1,abstract:"This chapter describes the usefulness of surgical technologies such as intraoperative MRI, 5-ALA fluorescence-guided surgery, and neuronavigation as tools to make brain tumor resections safer and more effective. The focuses are practical aspects and the relevant literature regarding the impact of their use in avoidance of complications, improvement in survival rates, and some tips and tricks acquired in the experience of our department. All three strategies have an important role in neuro-oncological surgery. The future probably will prove that the combination of these tools, selected case by case, is the best way to achieve the best results regarding safety and effectiveness.",signatures:"Luis Fernando Moura da Silva, Guilherme Augusto de Souza Machado\nand Ricardo Ramina",downloadPdfUrl:"/chapter/pdf-download/63881",previewPdfUrl:"/chapter/pdf-preview/63881",authors:[{id:"124582",title:"Dr.",name:"Luis Fernando",surname:"Moura Da Silva Jr.",slug:"luis-fernando-moura-da-silva-jr.",fullName:"Luis Fernando Moura Da Silva Jr."}],corrections:null},{id:"64925",title:"Management of Refractory/Aggressive Pituitary Adenomas Review of Current Treatment Options",doi:"10.5772/intechopen.81464",slug:"management-of-refractory-aggressive-pituitary-adenomas-review-of-current-treatment-options",totalDownloads:823,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Tumors of central nervous system (CNS) account for a small portion of tumors of human body, which includes tumors occurring in the parenchyma of brain and spinal cord as well as their coverings. 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In this chapter, we expanded the general discussion of vestibular schwannomas, discussing bases for an accurate diagnose and the technical aspects for the surgical approaches, drilling of internal auditory canal, and its reconstruction as well as the technical nuances when handling very small and large/residual tumors.",signatures:"Gustavo Jung and Ricardo Ramina",downloadPdfUrl:"/chapter/pdf-download/64569",previewPdfUrl:"/chapter/pdf-preview/64569",authors:[{id:"46275",title:"Prof.",name:"Ricardo",surname:"Ramina",slug:"ricardo-ramina",fullName:"Ricardo Ramina"},{id:"259905",title:"Dr.",name:"Gustavo",surname:"Jung",slug:"gustavo-jung",fullName:"Gustavo Jung"}],corrections:null},{id:"63100",title:"The Systemic Treatment of Glioma",doi:"10.5772/intechopen.80047",slug:"the-systemic-treatment-of-glioma",totalDownloads:971,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Gliomas have been treated by a specialized team including neurosurgery, radiation therapy, and neuro-oncology, as well as depending on integrated sophisticated facilities and multi-professional team. Despite these huge efforts to glioma treatment, glioblastoma, one of the most frequent gliomas, has median life expectance for just 15 months, so these results are still an unmet need. Related to the systemic treatment, some cancer approaches have been revolutionized with new strategies, such as immunotherapy, although in neuro-oncology, this alternative still has challenges to overcome. Throughout this chapter, relevant information and key points will be discussed to the best way to manage systemic treatment and improve glioma overall survival.",signatures:"Johnny Camargo",downloadPdfUrl:"/chapter/pdf-download/63100",previewPdfUrl:"/chapter/pdf-preview/63100",authors:[{id:"259778",title:"M.D.",name:"Johnny",surname:"Camargo",slug:"johnny-camargo",fullName:"Johnny Camargo"}],corrections:null},{id:"64101",title:"Role of Radiotherapy in High Grade Glioma",doi:"10.5772/intechopen.80923",slug:"role-of-radiotherapy-in-high-grade-glioma",totalDownloads:995,totalCrossrefCites:1,totalDimensionsCites:2,hasAltmetrics:0,abstract:"The aim of this review is to explore the changing utility of radiotherapy in the treatment of patients with glioblastoma over the past decades. Surgery and radiotherapy has always been the cornerstone of treatment of glioblastoma, but techniques have significantly advanced over this time. We selected the main studies that support the advances of radiotherapy in the present day as well as controversies in several aspects of the treatment will be approached; definition of the target volume in the magnetic resonance imaging (MRI) planning, size of the margins around the target volume; prescribed dose (satnadard vs. hypofactionated); management of glioblastoma in elderly; review role of radiosurgery past and new potential use in recurrence and the evidence of reirradiation in patients with local recurrence. 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However, in the case of irrigated paddy soil, there are several farmers’ fields in Japan which have not received any fertilizers for more than a decade but sustained rice yield at around 400 g m−2, i.e., about 80% of the conventionally fertilized fields [1, 2, 3].
The wonder of sustaining rice yield without fertilizer input may be explained by the unconscious input of nutrients to lowland fields through irrigation, rainfall, and biological nitrogen (N) fixation [4]. The advantage of lowland rice over upland rice can be found in the nutrient omission trials carried out throughout the country before chemical fertilizer was prevailed [5]. As shown in Figure 1, N was the most limiting element for both lowland and upland rice. For lowland rice, however, the percentage of yield loss caused by the omission of fertilizers differed with the growth conditions; 22 and 47% under field and pot conditions, respectively. Such a discrepancy was not observed for upland rice. With a closer look at the response of lowland rice to the omission of potassium (K) and phosphorus (P) under field conditions, the omission of these elements also caused more than 10% decrease of the yield in more than 20% of the paddy fields surveyed (Figure 2). Accordingly, K or P began to limit rice yield in some of the paddy fields when N limitation was removed by the application of N fertilizer.
Response of the yield of lowland rice and upland rice to the omission of N, P, and K fertilizers in Japan (adapted from [
Response of the yield of lowland rice to the omission of N, P, and K fertilizers in Japan (adapted from [
These results contributed to predict the necessary amount and type of chemical fertilizers applied to paddy fields. Figure 3 shows the temporal changes in the average rates of chemical fertilizer applied to paddy fields in Japan [6]. In 1950, N was applied at a higher rate than P and K. With time, the rates of P and K became comparable to the rate of N. This is probably because of the alleviation of N limitation and the use of compound fertilizer containing N and other nutrients. In 1970, more than 60% of N, P, and K were applied together in the form of compound fertilizer. The application rates of all nutrients increased rapidly by 1970 and reached a plateau around 1980. Then, the rates decreased from 1990 to 2015. The amount of N applied in 2011–2015 (60 kg ha−1) became smaller than the amount of N applied in 1950 (65 kg ha−1). This would be partly because the percentage of fertilizer N recovered by rice plants was significantly increased by the development of new techniques, e.g., side-dressing of polyolefin-coated urea that can supply N to rice roots according to crop demand. But a more plausible reason is the introduction of the
Rates of chemical fertilizer application to paddy fields in Japan from 1950 to 2015. The values before 1970 were cited from FAO [
From these backgrounds, rice and other crops produced with reduced input of chemical fertilizers and agrochemicals have been attracting more attention by consumers. In 2001, the Japanese government established the guidelines for the certification of crops produced with chemical fertilizers and agrochemicals at less than 50% of the conventional dosage in each region. The area of production of such crops amounted to 0.12 million ha (2.6% of total arable land) in 2017. Organic farming, where chemical fertilizer is fully replaced with organic fertilizer, is also increasing gradually, although the area of organic-farming fields is still 0.5% of the total area of arable land in 2017. The most extreme way of farming is the production of crops without using any chemical fertilizers and agrochemicals. Such no-input farming is called
These histories clearly show that no-input farming in Japan has been developed as a result of the past high-input farming, and it does not represent various types of no-input farming systems in the world. Almost all no-input paddy fields in Japan had received chemical fertilizers and agrochemicals before no-input farming was introduced, and these fields are different from the absolutely no-input fields in other countries that have not received any chemicals since land reclamation.
Recently, no-input rice farming in Japan has been recognized as an economically feasible farming system. Due to the very limited availability, rice produced by no-input farming has been sold at twice or more the price of rice produced by conventional farming [10]. Besides the price of the products, the level of rice yield and its sustainability are also important for farmers [1]. Several researchers have compared rice yield among no-input paddy fields with different periods after introducing no-input farming [1, 2, 3]. However, most of the previous studies have used a space-for-time substitution approach instead of monitoring rice yield and soil fertility over years. Thus, it is uncertain how much and how long such no-input farming can sustain rice yield and soil fertility under various environmental conditions.
In order to better understand the sustainability of no-input rice farming in Japan, I briefly review previous results obtained from the long-term field experiments including our no-input trial. The main topics in this review are (1) rice yield and soil fertility under no-input farming, (2) the environmental factors affecting rice growth and soil fertility under no-input farming, and (3) the dynamics of soil K under no-input and high-input rice farming systems.
In 1990, Neera et al. [1] surveyed 542 no-input fields in 17 prefectures in Japan and compared rice yield with the average yield by conventional farming according to the corresponding municipal statistics. The sampling of rice plants was performed at one representative site in a paddy field at the rate of 30 hills per field [11]. On average of the surveyed fields, the period of no-input farming was 10.7 years, and the yield of brown rice by no-input farming (445 g m−2) amounted to 87% of the yield by conventional farming (511 g m−2). When the results were compared among different regions, the yield by no-input farming was significantly lower than the yield by conventional farming at six prefectures in Tohoku district located in northern Japan (Figure 4). The yield was relatively high in Tohoku district, and the average yield after no-input farming for 28–40 years amounted to 456 g m−2 (
Relationship between rice yields obtained from municipal statistics and from no-input farming (adapted from [
Following this pioneering work, however, only a few researchers have attempted to identify the factors affecting rice yield under no-input farming. Hosoya and Sugiyama [2] surveyed 16 no-input fields in four prefectures (Aomori, Iwate, Miyagi, and Niigata) in northern Japan. The yield of brown rice in no-input fields was positively correlated with the number of panicles (
Compared to rice yield, much less attention has been paid to soil fertility under no-input farming. When the results in the above two reports [3, 12] were combined, total N content in the surface soil showed a large variation among the fields (Figure 5), and the coefficient of variation became 47%. The content was similar to or higher than the national average (2.39 g kg−1) in several fields with a no-input history for more than 5 years. The highest content was recorded in a field with no fertilizer input for 21 years. The soil in this field was classified as one of the Andosols, whereas the soil in all the other fields was classified as non-Andosols according to the digital soil map of Japan [13].
Relationship between the period after ceasing fertilization to paddy fields and the content of total N in the surface soil (adapted from [
For other soil properties, Kuwamura [8] evaluated the characteristics of soil chemical properties under no-input farming by using a space-for-time substitution approach. An extensive survey was conducted by analyzing 654 soil samples collected from no-input paddy fields throughout Japan from 1992 to 1996. The period of no-input farming ranged from 0 to 49 years. The results were compared with the contemporary national soil inventory data (third survey from 1989 to 1993 in [14]). The average depth of a plow layer in no-input fields (18.5 cm) was larger than that in the conventional paddy fields (14.6 cm). The average content of total N in the surface soil (2.6 g kg−1) was slightly higher than the national average (2.42 g kg−1). On the other hand, the average content of mineralizable N in the surface soil (118 mg kg−1) was slightly lower than the national average (145 mg kg−1). The average content of available P (Truog P) in the surface soil (126 mgP2O5 kg−1) was much lower than the national average (298 mgP2O5 kg−1). When the soil samples were limited to those classified as non-Andosols (
The above results were obtained from the one-time survey of no-input fields. Due to the lack of long-term monitoring data, it is difficult to make a simple conclusion. Nevertheless, it can be roughly concluded that rice yield and soil fertility in no-input paddy fields were influenced not only by the period of no-input farming but also by various environmental and management factors operating at regional and field scales.
In this section, I introduce our results obtained from a 5-year no-input trial [15]. To estimate the environmental factors that enable soil fertility to be maintained without fertilization, application of fertilizers to a paddy field at Kyoto University Farm in Takatsuki, Japan, was ceased in 2010. Both planted and unplanted plots were installed in the field (Figure 6). Then, changes in rice yield and soil fertility in the field were evaluated until 2015. Surface soil samples were collected from both planted and unplanted plots before transplanting and after harvesting of rice plants. At harvesting, rice straw was also removed from the field. The physicochemical properties of the samples were monitored. Rice yield and the uptake of N and K by rice plants were also analyzed. The soil in this field was classified as non-Andosol (Gley lowland soil) according to Digital Soil Map of Japan [13]. The surface soil was relatively sandy (sand content higher than 60%) and had the following properties at the start of the experiment: pH(H2O)—5.95; total C—20.2 g kg−1; total N—1.99 g kg−1; mineralizable N—156 mg kg−1, available P (Bray no.2 P)—484 mgP kg−1; and cation exchange capacity—10.4 cmolc kg−1. As the soil was relatively rich in available P due to the long-term application of chemical fertilizers, we focused on the dynamics of N and K in this field.
Rice plants (cv. Hinohikari) at panicle initiation stage grown without fertilization in Kyoto University farm (right side). In the field with an area of 10 a, two unplanted plots were equipped next to the planted plots. The color of rice leaves in this field was yellower than the color in a fertilized field (left side), suggesting that N was the most limiting nutrient in the unfertilized field. The photograph was taken by the author on July 30, 2012, the third year after ceasing fertilization to this field.
During the experimental period, the yield of unhulled rice was relatively stable; 630, 621, 618, 551, and 639 g m−2 from 2010 to 2014, respectively. On the other hand, the levels of mineralizable N, total N, and nonexchangeable K (boiling 1 mol L−1 HNO3-extractable K minus exchangeable K) in the surface soil of both planted and unplanted plots began to significantly decrease after three cropping seasons (Figure 7). The amount of total N and boiling HNO3-extractable K (exchangeable K plus nonexchangeable K) decreased from the surface soil (0–10 cm) of the unplanted plot during the 5 years was estimated to be 55 and 7.2 g m−2, respectively, assuming a bulk density of 1.0 g cm−3. On the other hand, the amount of N and K taken up by a single cropping of rice plants in 2012 was 8.3 and 11.5 g m−2, respectively. Accordingly, N was lost from the unplanted plots with the magnitude comparable to the removal of N by rice plants. The results in Figure 7 also indicated that the continuous removal of N and K from soil caused the significant depletions of mineralizable N and nonexchangeable K but not of more readily extractable fractions (NH4+-N and exchangeable K). By more frequent soil sampling and analysis conducted in 2012, it was revealed that the concentration of exchangeable K in soil decreased from transplanting to the maximum tillering stage and then recovered to the initial level from the booting stage to winter [15]. The reason for the lack of depletion of exchangeable K after continuous removal of K is discussed in the last section.
Temporal changes of surface soil properties at planted (open circle) and unplanted (filled circle) plots in the unfertilized field (adapted from [
In 2013, the fourth year after ceasing fertilization, fertilizer trials with N or K application were conducted under both field and pot conditions to identify which element limited rice growth (Figure 8). Distilled water was used for irrigation in the pot experiment, whereas river or underground water was used for irrigation in the field experiment; total N and K concentration was measured at each irrigation event. The fertilizer trials demonstrated that the element limiting rice growth was K or N under pot or field conditions, respectively (Figure 8). To confirm this result, another nutrient omission trial was conducted in 2016 by using the surface soil collected after six harvests of rice without fertilization. Among the nutrients omitted (N, K, and Si), K was the most limiting nutrient when distilled water was used for irrigation (Figure 9). These results indicate that K, but not N, was the most limiting nutrient in the unfertilized soil and that the amount of K supplied by irrigation was sufficient to overcome the low K status of the unfertilized soil and meet plant demand. This should be the main reason why fertilizer responses were different between pot and field conditions. In other words, previous results on the nutrient omission trials (Figures 1 and 2) may have overestimated the ability of soil to supply nutrients to rice plants by allowing the external input of nutrients through irrigation.
Dry matter weight of rice shoot (cv. Hinohikari) at maturity stage as influenced by the fertilizer application and growth conditions (adapted from [
Rice plants (cv. Hinohikari) at milk ripe stage grown in Takatsuki soil collected from the field without fertilizer application for 6 years (Moritsuka, unpublished). Distilled water was used for irrigation. The values indicate the average ± standard deviation of the shoot dry matter weight (g pot−1,
In our field, the average concentration of K in irrigation water was 3.8 mg L−1 in 2013. If the amount of irrigation was assumed to be 1000 kg m−2, the input of K to the field through irrigation becomes 3.8 g m−2. This amount is slightly higher than the amount of K in rice panicles at maturity stage (3.0 g m−2 in our study). Thus, the input of K by irrigation may meet the plant’s demand if rice straw is not removed from the fields and the irrigation water is rich in K (>2 mg L−1).
Figure 10 shows the average K concentration in river water sampled from 225 rivers throughout Japan [16]. The sampling was carried out in 1940s and 1950s, when the eutrophication of river water was not a serious problem. The national average of the K concentration in river water was 1.20 mg L−1 with a large spatial variation (coefficient of variation = 57%). The concentration of K was higher than 2 mg L−1 in 24 rivers (10.7%), and 13 out of 24 rivers were located in Kyushu district in southern Japan. Several rivers originating from the Aso and Kirishima volcanic areas in Kyushu district showed very high concentrations of both K and Si. These results suggest that, in some of the watersheds in Japan, the input of K by irrigation of river water can meet the plant’s demand even without the application of K fertilizer.
Average K concentration in river water sampled from 225 rivers in Japan (adapted from [
In contrast to K, the national average of inorganic N (NH4+ and NO3−) concentration in river water was 0.28 mgN L−1 (coefficient of variation = 99%) [16]. The input of N by irrigation cannot meet the plant’s demand unless river water is polluted by eutrophication. As shown in Figure 5, there was a large variation in total N content in no-input paddy soils even when an outlier classified as an Andosol was removed. Such a large variation may have originated from the capacity of soil clay particles to accumulate organic matter containing N. This is because a significant negative correlation was observed between the sand content and the total N content in agricultural surface soils frequently used for paddy fields (Figure 11) [17].
Relationship between the sand content and the total N content in soils frequently used for paddy fields (adapted from [
Summarizing the results of this section, the input of K through irrigation and high-clay content in soil were considered the key environmental factors that enable to continue no-input farming. These factors are indebted to geographical conditions. Furthermore, the accumulation of fertilizer-derived P in the surface soil before ceasing fertilization may be another important factor. As a result of the alleviation of K and P deficiencies in the field, N became the most limiting nutrient in our experimental field. Enhancing the biological N fixation by growing leguminous plants after rice harvest and returning the plant residue to soil before transplanting may help to alleviate the N limitation to rice growth.
In the last section, I focus on the dynamics of K in paddy soil. In our experimental field, the concentration of nonexchangeable K in soil decreased significantly by the no-input farming, whereas the concentration of exchangeable K in soil was relatively constant and tended to increase from harvest to next transplanting (Figure 7). In this section, these observations are compared with previous results.
Srinivasa Rao et al. [18] evaluated the long-term changes in soil K forms under rice-rice cropping system with different fertilizer management. The experiment was carried out at Hyderabad in India. Surface soils were collected four times over 20 years, and the samples were analyzed for the different forms of K, including nonexchangeable K (boiling 1 mol L−1 HNO3-extractable K minus exchangeable K). Figure 12 shows the temporal changes in the concentrations of soluble, exchangeable, and nonexchangeable K in surface paddy soil as influenced by different fertilizer treatments. Among the three K forms, nonexchangeable K showed the largest depletion over 20 years (Figure 12). The amount of HNO3-extractable K decreased over 20 years was quantitatively comparable to the net output of K estimated from the total amount of crop removal and fertilization. Thus, continuous cropping of rice caused a significant depletion of nonexchangeable K, while the concentrations of more readily extractable K fractions were relatively constant. In a soil test, we usually measure the sum of soluble and exchangeable K by extracting soil with neutral 1 mol L−1 ammonium acetate. However, compared with nonexchangeable K, these K forms were much less sensitive to the long-term removal of K by rice plants. Based on these results, the authors concluded that the analysis of nonexchangeable K in soil should be added to a conventional soil test for better predicting K fertilizer requirements for long-term operation.
Effect of 20 years of rice-rice cropping and fertilizer application on the concentrations of soluble, exchangeable, and nonexchangeable K in surface paddy soil (adapted from [
The results of Srinivasa Rao et al. [18] agree well with our results (Figure 7) and also with the results from an extensive survey by Khan et al. [19]. By reviewing previous results from the long-term field experiments in the world and comparing the net changes of exchangeable K in the surface soil at the beginning and end of the study period with the net inputs of K due to long-term fertilization and crop removal, Khan et al. [19] revealed that the changes in the soil exchangeable K pool during the study period were much smaller than the net input of K to the field estimated from the total amount of K added and removed (Figure 13). In the case of our field, the net decrease of soil exchangeable K during the 5-year experiment amounted to only 5.2% of the cumulative K removed by rice plants (Figure 13). From these results, the authors concluded that a one-time measurement of soil exchangeable K cannot account for the highly dynamic interchange of K between exchangeable and nonexchangeable pools. Khan et al. [19]) also reported that the concentration of exchangeable K in soil was increased significantly by air-drying soil samples to the soil moisture content below 50 g kg−1, which is a conventional soil pretreatment required for sample homogenization.
Relationship between the net input of K due to long-term fertilization and crop removal and the net change of soil exchangeable K (adapted from [
In the case of Srinivasa Rao et al. [18], the application of farmyard manure in combination with chemical fertilizer contributed to recover the concentration of HNO3-extractable K to some extent (Figure 12). However, a few researchers have reported contrasting results; the co-application of manure over long periods did not necessarily increase the concentration of nonexchangeable K in soil [20, 21]. For example, Kitajima et al. [20] evaluated the effect of long-term co-application of farmyard manure on the K forms in the surface soil at three locations in Japan. As shown in Figure 14, the co-application of farmyard manure increased the concentration of exchangeable K (including soluble K) but decreased the concentration of nonexchangeable K (boiling 1 mol L−1 HNO3-extractable K minus exchangeable K) at all the locations. The authors suggested that farmyard manure accelerated the dissolution of K-bearing minerals in soil, by which nonexchangeable K was irreversibly transformed to exchangeable K. Regardless of the processes involved, the results in Figure 14 cannot be explained by the dynamic equilibrium between the exchangeable K and the nonexchangeable K which operates to minimize the concentration changes of both K forms.
Effect of long-term co-application of farmyard manure (FYM) on the concentrations of exchangeable and nonexchangeable K in surface paddy soil (adapted from [
Yamashita et al. [22] recently reported that microbial biomass K in the surface paddy soil is detectable by the conventional fumigation-extraction approach and that the concentration of microbial biomass K was increased by the continuous application of compost to paddy fields. Combining these results with those by Khan et al. [19], it is plausible to consider that exchangeable K pool evaluated by using air-dried soil samples inevitably includes microbial biomass K. The increase of exchangeable K by the long-term application of farmyard manure (Figure 14) may be due to the contamination of microbial biomass K in the exchangeable K fraction. From these interpretations, the dynamics of soil K forms in the soil-plant-microbe systems are depicted in Figure 15 by referring to the concept proposed by Asakawa and Yamashita [23]. The soundness and practical usefulness of this concept need to be evaluated in future experiments.
Dynamics of K in the surface agricultural soil driven by crop plants, soil microbes, and fertilization (adapted from [
In summary, our results on soil K dynamics agreed well with previous results from long-term field experiments. Accordingly, it can be generally concluded that soil K depletion caused by long-term exhaustive cropping should be evaluated by monitoring the decrease of soil nonexchangeable K rather than that of exchangeable K. Furthermore, I hypothesized that the dynamics of soil microbial biomass K may cause the fluctuations of soil exchangeable K measured after air-drying pretreatment.
In this review, no-input rice farming in Japan was evaluated from the viewpoint of soil sustainability. It can be concluded that soil fertility under this farming system has been supported by various environmental and management factors, especially the input of K through irrigation, high-clay content in soil, and accumulation of fertilizer P applied previously to the soil. In the case of our no-input trial for 5 years, a significant depletion of mineralizable N and nonexchangeable K was observed after three cropping seasons, and rice growth was limited by soil K supply when the input of K by irrigation was restricted. These results highlight the importance of monitoring the dynamics of multiple soil nutrients for several years.
This is a brief overview of the main steps involved in publishing with IntechOpen Compacts, Monographs and Edited Books. Once you submit your proposal you will be appointed a Author Service Manager who will be your single point of contact and lead you through all the described steps below.
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Catalysis particularly using supported gold nanoparticles (AuNPs) has attracted immense research interest due to their unique properties and greater potentiality that is directly related to their particle size. The primary objective of this chapter is to provide comprehensive overview about gold metal nanoparticles (AuNPs) and their application as promising catalysts. This chapter contains six sections in total. Section 1 starts with a general introduction, recent progress, and brief summary of the application of supported AuNPs as promising catalysts for different applications. Section 2 briefs the properties and stability of gold nanoparticles. Section 3 reviews the preparation methods of supported AuNPs for a wide range of catalytic applications. Section 4 describes briefly some of the most commonly reported supported AuNPs for different applications. Section 5 concentrates on our own results related to the application of supported AuNPs in heterogeneous catalysis. In this section, the oxidation of cyclohexane (CH) and benzyl alcohol (BA) to adipic acid (AA), benzaldehyde (BAl), and ammoxidation of 2-methylpyrazine to 2-cyanopyrazine are discussed. Finally, Section 6 describes, main points and outlook are summarized.",book:{id:"5310",slug:"catalytic-application-of-nano-gold-catalysts",title:"Catalytic Application of Nano-Gold Catalysts",fullTitle:"Catalytic Application of Nano-Gold Catalysts"},signatures:"Ahmad Alshammari and Venkata Narayana Kalevaru",authors:[{id:"178547",title:"Dr.",name:"Ahmad",middleName:null,surname:"Alshammari",slug:"ahmad-alshammari",fullName:"Ahmad Alshammari"},{id:"180753",title:"Dr.",name:"V. Narayana",middleName:null,surname:"Kalevaru",slug:"v.-narayana-kalevaru",fullName:"V. Narayana Kalevaru"}]},{id:"50852",doi:"10.5772/63729",title:"Synthesis of Gold Nanoparticles Using Amino Acids by Light Irradiation",slug:"synthesis-of-gold-nanoparticles-using-amino-acids-by-light-irradiation",totalDownloads:3602,totalCrossrefCites:3,totalDimensionsCites:10,abstract:"The synthesis of nanoparticles is generally carried out by chemical reduction, which is effective but uses a number of toxic substances, making the process potentially harmful to the environment. Thus, as part of the search for environmentally friendly or green synthetic methods, this chapter aimed to present the synthesis of gold nanoparticles (AuNPs) using only HAuCl4, Milli-Q water, white light from a xenon lamp, and amino acids. A total of 21 amino acids were studied, and the shapes and sizes of the resultant nanoparticles were evaluated. The products were characterized by ultraviolet-visible (UV-Vis) and fluorescence spectroscopy, zeta potential measurements, and transmission electron microscopy. The synthesis of the AuNPs was successful with 18 amino acids, and the best results were obtained with aspartic acid, arginine, threonine, tryptophan, and valine. The nanoparticles were spherical and their sizes ranged from 5 to 100 nm. Changes in pH were required to improve the stability of the colloidal suspensions.",book:{id:"5310",slug:"catalytic-application-of-nano-gold-catalysts",title:"Catalytic Application of Nano-Gold Catalysts",fullTitle:"Catalytic Application of Nano-Gold Catalysts"},signatures:"Lilia Coronato Courrol and Ricardo Almeida de Matos",authors:[{id:"183894",title:"Ph.D.",name:"Lilia",middleName:null,surname:"Courrol",slug:"lilia-courrol",fullName:"Lilia Courrol"},{id:"185446",title:"MSc.",name:"Ricardo",middleName:null,surname:"Matos",slug:"ricardo-matos",fullName:"Ricardo Matos"}]},{id:"51091",doi:"10.5772/64081",title:"Nanoporous Gold Films as Catalyst",slug:"nanoporous-gold-films-as-catalyst",totalDownloads:2029,totalCrossrefCites:2,totalDimensionsCites:6,abstract:"Nanoporous gold (NPG) is reviewed as a catalyst. Various preparation methods were first reviewed for NPG and its structure. Applications of this catalyst in CO oxidation, hydrogen oxidation, hydrogen production are discussed. Regarding CO oxidation, detailed studies on reaction mechanism and density functional theory (DFT) calculations were also reviewed. Not only as a model reaction but also practical aspects of removing CO residue in hydrogen stream are discussed. Beyond those simple reactions, the application of NPG to more complicated reactions such as alcohol oxidation is reviewed. Selective aerobic oxidation of gas‐phase alcohols is first reviewed and reactions in liquid phase are discussed. Finally, future prospects of NPG as a catalyst for more complicated reactions such as organic synthesis are briefly discussed.",book:{id:"5310",slug:"catalytic-application-of-nano-gold-catalysts",title:"Catalytic Application of Nano-Gold Catalysts",fullTitle:"Catalytic Application of Nano-Gold Catalysts"},signatures:"Sang Hoon Kim",authors:[{id:"183817",title:"Dr.",name:"Sang Hoon",middleName:null,surname:"Kim",slug:"sang-hoon-kim",fullName:"Sang Hoon Kim"}]},{id:"51939",doi:"10.5772/64770",title:"Electrochemical Reactivity at Free and Supported Gold Nanocatalysts Surface",slug:"electrochemical-reactivity-at-free-and-supported-gold-nanocatalysts-surface",totalDownloads:2112,totalCrossrefCites:2,totalDimensionsCites:2,abstract:"This chapter presents an overview on size, structure, morphology, composition as well as the effect of the support on the electrocatalytic properties of gold nanoparticles (AuNPs). It was found that the electrocatalytic properties of unsupported AuNPs strongly depend on their size and shape. Consequently, the electrocatalytic properties of AuNPs can be tuned. Furthermore, to design high-performance electrocatalysts with minimal precious metal content and cost, the direct immobilization of metal NPs onto carbon-based substrates during their synthesis constitutes another elegant alternative and has been thoroughly examined. These “easy-to-use” supports as scaffolds for AuNPs, namely carbon black, carbon paper, etc., offer beneficial contributions. Indeed, thanks to their high available surface area, good electronic conductivity and synergistic effect between the chemical species present on their surface and the loaded NPs, carbon-based supports enable maximizing the efficient utilization of the catalysts toward drastic enhancement in both activity and durability. We also examined different judicious combinations of (electro)analytical techniques for the unambiguous determination of the reaction product(s) over the Au-based nanocatalysts, using glucose as model molecule given its importance in electrocatalysis. The performances of carbon-supported AuNPs as anode materials in direct glucose fuel cell in alkaline medium were also discussed.",book:{id:"5310",slug:"catalytic-application-of-nano-gold-catalysts",title:"Catalytic Application of Nano-Gold Catalysts",fullTitle:"Catalytic Application of Nano-Gold Catalysts"},signatures:"Seydou Hebié, Yaovi Holade, Karine Servat, Boniface K. Kokoh and\nTêko W. Napporn",authors:[{id:"28387",title:"Prof.",name:"Boniface",middleName:null,surname:"Kokoh",slug:"boniface-kokoh",fullName:"Boniface Kokoh"},{id:"29443",title:"Dr.",name:"Karine",middleName:null,surname:"Servat",slug:"karine-servat",fullName:"Karine Servat"},{id:"30682",title:"Dr.",name:"Teko",middleName:null,surname:"Napporn",slug:"teko-napporn",fullName:"Teko Napporn"},{id:"183917",title:"Dr.",name:"Seydou",middleName:null,surname:"Hebie",slug:"seydou-hebie",fullName:"Seydou Hebie"},{id:"183918",title:"Dr.",name:"Yaovi",middleName:null,surname:"Holade",slug:"yaovi-holade",fullName:"Yaovi Holade"}]},{id:"51930",doi:"10.5772/64103",title:"Gold-Catalysed Reactions",slug:"gold-catalysed-reactions",totalDownloads:1937,totalCrossrefCites:0,totalDimensionsCites:1,abstract:"In recent years, there have been three significant pieces of research which helped propel gold catalysis research into the forefront: the discoveries that gold/silica can catalyse the hydrogenation of pentene, that gold on carbon can be used in the hydrochlorination of acetylene and that deposition-precipitation (DP) methods can be used to prepare nanogold on titania capable of enabling the oxidation of CO at very low temperatures. The synthesis of small gold particles, their characterisation and peculiar properties are considered together with their behaviour as heterogeneous catalysts for a variety of reactions. Some of the issues concerning the practical application of gold catalysts are also discussed.",book:{id:"5310",slug:"catalytic-application-of-nano-gold-catalysts",title:"Catalytic Application of Nano-Gold Catalysts",fullTitle:"Catalytic Application of Nano-Gold Catalysts"},signatures:"J.A. Moma, T.A. Ntho and Michael Scurrell",authors:[{id:"179872",title:"Prof.",name:"Mike",middleName:null,surname:"Scurrell",slug:"mike-scurrell",fullName:"Mike Scurrell"},{id:"183973",title:"Dr.",name:"John",middleName:null,surname:"Moma",slug:"john-moma",fullName:"John Moma"},{id:"183974",title:"Dr.",name:"Thabang",middleName:"Abraham",surname:"Ntho",slug:"thabang-ntho",fullName:"Thabang Ntho"}]}],mostDownloadedChaptersLast30Days:[{id:"51930",title:"Gold-Catalysed Reactions",slug:"gold-catalysed-reactions",totalDownloads:1934,totalCrossrefCites:0,totalDimensionsCites:1,abstract:"In recent years, there have been three significant pieces of research which helped propel gold catalysis research into the forefront: the discoveries that gold/silica can catalyse the hydrogenation of pentene, that gold on carbon can be used in the hydrochlorination of acetylene and that deposition-precipitation (DP) methods can be used to prepare nanogold on titania capable of enabling the oxidation of CO at very low temperatures. The synthesis of small gold particles, their characterisation and peculiar properties are considered together with their behaviour as heterogeneous catalysts for a variety of reactions. Some of the issues concerning the practical application of gold catalysts are also discussed.",book:{id:"5310",slug:"catalytic-application-of-nano-gold-catalysts",title:"Catalytic Application of Nano-Gold Catalysts",fullTitle:"Catalytic Application of Nano-Gold Catalysts"},signatures:"J.A. Moma, T.A. Ntho and Michael Scurrell",authors:[{id:"179872",title:"Prof.",name:"Mike",middleName:null,surname:"Scurrell",slug:"mike-scurrell",fullName:"Mike Scurrell"},{id:"183973",title:"Dr.",name:"John",middleName:null,surname:"Moma",slug:"john-moma",fullName:"John Moma"},{id:"183974",title:"Dr.",name:"Thabang",middleName:"Abraham",surname:"Ntho",slug:"thabang-ntho",fullName:"Thabang Ntho"}]},{id:"52066",title:"Supported Gold Nanoparticles as Promising Catalysts",slug:"supported-gold-nanoparticles-as-promising-catalysts",totalDownloads:3092,totalCrossrefCites:5,totalDimensionsCites:11,abstract:"In recent times, gold nanoparticles (AuNPs) either in the form of colloids or as supported nanoparticles are being extensively used as efficient redox catalyst materials. Catalysis particularly using supported gold nanoparticles (AuNPs) has attracted immense research interest due to their unique properties and greater potentiality that is directly related to their particle size. The primary objective of this chapter is to provide comprehensive overview about gold metal nanoparticles (AuNPs) and their application as promising catalysts. This chapter contains six sections in total. Section 1 starts with a general introduction, recent progress, and brief summary of the application of supported AuNPs as promising catalysts for different applications. Section 2 briefs the properties and stability of gold nanoparticles. Section 3 reviews the preparation methods of supported AuNPs for a wide range of catalytic applications. Section 4 describes briefly some of the most commonly reported supported AuNPs for different applications. Section 5 concentrates on our own results related to the application of supported AuNPs in heterogeneous catalysis. In this section, the oxidation of cyclohexane (CH) and benzyl alcohol (BA) to adipic acid (AA), benzaldehyde (BAl), and ammoxidation of 2-methylpyrazine to 2-cyanopyrazine are discussed. Finally, Section 6 describes, main points and outlook are summarized.",book:{id:"5310",slug:"catalytic-application-of-nano-gold-catalysts",title:"Catalytic Application of Nano-Gold Catalysts",fullTitle:"Catalytic Application of Nano-Gold Catalysts"},signatures:"Ahmad Alshammari and Venkata Narayana Kalevaru",authors:[{id:"178547",title:"Dr.",name:"Ahmad",middleName:null,surname:"Alshammari",slug:"ahmad-alshammari",fullName:"Ahmad Alshammari"},{id:"180753",title:"Dr.",name:"V. Narayana",middleName:null,surname:"Kalevaru",slug:"v.-narayana-kalevaru",fullName:"V. Narayana Kalevaru"}]},{id:"50852",title:"Synthesis of Gold Nanoparticles Using Amino Acids by Light Irradiation",slug:"synthesis-of-gold-nanoparticles-using-amino-acids-by-light-irradiation",totalDownloads:3602,totalCrossrefCites:3,totalDimensionsCites:9,abstract:"The synthesis of nanoparticles is generally carried out by chemical reduction, which is effective but uses a number of toxic substances, making the process potentially harmful to the environment. Thus, as part of the search for environmentally friendly or green synthetic methods, this chapter aimed to present the synthesis of gold nanoparticles (AuNPs) using only HAuCl4, Milli-Q water, white light from a xenon lamp, and amino acids. A total of 21 amino acids were studied, and the shapes and sizes of the resultant nanoparticles were evaluated. The products were characterized by ultraviolet-visible (UV-Vis) and fluorescence spectroscopy, zeta potential measurements, and transmission electron microscopy. The synthesis of the AuNPs was successful with 18 amino acids, and the best results were obtained with aspartic acid, arginine, threonine, tryptophan, and valine. The nanoparticles were spherical and their sizes ranged from 5 to 100 nm. Changes in pH were required to improve the stability of the colloidal suspensions.",book:{id:"5310",slug:"catalytic-application-of-nano-gold-catalysts",title:"Catalytic Application of Nano-Gold Catalysts",fullTitle:"Catalytic Application of Nano-Gold Catalysts"},signatures:"Lilia Coronato Courrol and Ricardo Almeida de Matos",authors:[{id:"183894",title:"Ph.D.",name:"Lilia",middleName:null,surname:"Courrol",slug:"lilia-courrol",fullName:"Lilia Courrol"},{id:"185446",title:"MSc.",name:"Ricardo",middleName:null,surname:"Matos",slug:"ricardo-matos",fullName:"Ricardo Matos"}]},{id:"51091",title:"Nanoporous Gold Films as Catalyst",slug:"nanoporous-gold-films-as-catalyst",totalDownloads:2026,totalCrossrefCites:2,totalDimensionsCites:6,abstract:"Nanoporous gold (NPG) is reviewed as a catalyst. Various preparation methods were first reviewed for NPG and its structure. Applications of this catalyst in CO oxidation, hydrogen oxidation, hydrogen production are discussed. Regarding CO oxidation, detailed studies on reaction mechanism and density functional theory (DFT) calculations were also reviewed. Not only as a model reaction but also practical aspects of removing CO residue in hydrogen stream are discussed. Beyond those simple reactions, the application of NPG to more complicated reactions such as alcohol oxidation is reviewed. Selective aerobic oxidation of gas‐phase alcohols is first reviewed and reactions in liquid phase are discussed. Finally, future prospects of NPG as a catalyst for more complicated reactions such as organic synthesis are briefly discussed.",book:{id:"5310",slug:"catalytic-application-of-nano-gold-catalysts",title:"Catalytic Application of Nano-Gold Catalysts",fullTitle:"Catalytic Application of Nano-Gold Catalysts"},signatures:"Sang Hoon Kim",authors:[{id:"183817",title:"Dr.",name:"Sang Hoon",middleName:null,surname:"Kim",slug:"sang-hoon-kim",fullName:"Sang Hoon Kim"}]},{id:"51939",title:"Electrochemical Reactivity at Free and Supported Gold Nanocatalysts Surface",slug:"electrochemical-reactivity-at-free-and-supported-gold-nanocatalysts-surface",totalDownloads:2111,totalCrossrefCites:2,totalDimensionsCites:2,abstract:"This chapter presents an overview on size, structure, morphology, composition as well as the effect of the support on the electrocatalytic properties of gold nanoparticles (AuNPs). It was found that the electrocatalytic properties of unsupported AuNPs strongly depend on their size and shape. Consequently, the electrocatalytic properties of AuNPs can be tuned. Furthermore, to design high-performance electrocatalysts with minimal precious metal content and cost, the direct immobilization of metal NPs onto carbon-based substrates during their synthesis constitutes another elegant alternative and has been thoroughly examined. These “easy-to-use” supports as scaffolds for AuNPs, namely carbon black, carbon paper, etc., offer beneficial contributions. Indeed, thanks to their high available surface area, good electronic conductivity and synergistic effect between the chemical species present on their surface and the loaded NPs, carbon-based supports enable maximizing the efficient utilization of the catalysts toward drastic enhancement in both activity and durability. We also examined different judicious combinations of (electro)analytical techniques for the unambiguous determination of the reaction product(s) over the Au-based nanocatalysts, using glucose as model molecule given its importance in electrocatalysis. The performances of carbon-supported AuNPs as anode materials in direct glucose fuel cell in alkaline medium were also discussed.",book:{id:"5310",slug:"catalytic-application-of-nano-gold-catalysts",title:"Catalytic Application of Nano-Gold Catalysts",fullTitle:"Catalytic Application of Nano-Gold Catalysts"},signatures:"Seydou Hebié, Yaovi Holade, Karine Servat, Boniface K. Kokoh and\nTêko W. Napporn",authors:[{id:"28387",title:"Prof.",name:"Boniface",middleName:null,surname:"Kokoh",slug:"boniface-kokoh",fullName:"Boniface Kokoh"},{id:"29443",title:"Dr.",name:"Karine",middleName:null,surname:"Servat",slug:"karine-servat",fullName:"Karine Servat"},{id:"30682",title:"Dr.",name:"Teko",middleName:null,surname:"Napporn",slug:"teko-napporn",fullName:"Teko Napporn"},{id:"183917",title:"Dr.",name:"Seydou",middleName:null,surname:"Hebie",slug:"seydou-hebie",fullName:"Seydou Hebie"},{id:"183918",title:"Dr.",name:"Yaovi",middleName:null,surname:"Holade",slug:"yaovi-holade",fullName:"Yaovi Holade"}]}],onlineFirstChaptersFilter:{topicId:"382",limit:6,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:89,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:104,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:32,numberOfPublishedChapters:318,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:12,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:141,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:133,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:113,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:107,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:5,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:15,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}},{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}}]},series:{item:{id:"6",title:"Infectious Diseases",doi:"10.5772/intechopen.71852",issn:"2631-6188",scope:"This series will provide a comprehensive overview of recent research trends in various Infectious Diseases (as per the most recent Baltimore classification). Topics will include general overviews of infections, immunopathology, diagnosis, treatment, epidemiology, etiology, and current clinical recommendations for managing infectious diseases. Ongoing issues, recent advances, and future diagnostic approaches and therapeutic strategies will also be discussed. This book series will focus on various aspects and properties of infectious diseases whose deep understanding is essential for safeguarding the human race from losing resources and economies due to pathogens.",coverUrl:"https://cdn.intechopen.com/series/covers/6.jpg",latestPublicationDate:"June 25th, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:13,editor:{id:"131400",title:"Prof.",name:"Alfonso J.",middleName:null,surname:"Rodriguez-Morales",slug:"alfonso-j.-rodriguez-morales",fullName:"Alfonso J. 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He is an External Professor, Master in Research on Tropical Medicine and International Health, Universitat de Barcelona, Spain. He is also a professor at the Master in Clinical Epidemiology and Biostatistics, Universidad Científica del Sur, Lima, Peru. In 2021 he has been awarded the “Raul Isturiz Award” Medal of the API. Also, in 2021, he was awarded with the “Jose Felix Patiño” Asclepius Staff Medal of the Colombian Medical College, due to his scientific contributions to COVID-19 during the pandemic. He is currently the Editor in Chief of the journal Travel Medicine and Infectious Diseases. His Scopus H index is 47 (Google Scholar H index, 68).",institutionString:"Institución Universitaria Visión de las Américas, Colombia",institution:null},editorTwo:null,editorThree:null},subseries:{paginationCount:4,paginationItems:[{id:"3",title:"Bacterial Infectious Diseases",coverUrl:"https://cdn.intechopen.com/series_topics/covers/3.jpg",isOpenForSubmission:!1,annualVolume:null,editor:null,editorTwo:null,editorThree:null},{id:"4",title:"Fungal Infectious Diseases",coverUrl:"https://cdn.intechopen.com/series_topics/covers/4.jpg",isOpenForSubmission:!0,annualVolume:11400,editor:{id:"174134",title:"Dr.",name:"Yuping",middleName:null,surname:"Ran",slug:"yuping-ran",fullName:"Yuping Ran",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bS9d6QAC/Profile_Picture_1630330675373",biography:"Dr. Yuping Ran, Professor, Department of Dermatology, West China Hospital, Sichuan University, Chengdu, China. Completed the Course Medical Mycology, the Centraalbureau voor Schimmelcultures (CBS), Fungal Biodiversity Centre, Netherlands (2006). International Union of Microbiological Societies (IUMS) Fellow, and International Emerging Infectious Diseases (IEID) Fellow, Centers for Diseases Control and Prevention (CDC), Atlanta, USA. Diploma of Dermatological Scientist, Japanese Society for Investigative Dermatology. Ph.D. of Juntendo University, Japan. Bachelor’s and Master’s degree, Medicine, West China University of Medical Sciences. Chair of Sichuan Medical Association Dermatology Committee. General Secretary of The 19th Annual Meeting of Chinese Society of Dermatology and the Asia Pacific Society for Medical Mycology (2013). In charge of the Annual Medical Mycology Course over 20-years authorized by National Continue Medical Education Committee of China. Member of the board of directors of the Asia-Pacific Society for Medical Mycology (APSMM). Associate editor of Mycopathologia. Vice-chief of the editorial board of Chinses Journal of Mycology, China. Board Member and Chair of Mycology Group of Chinese Society of Dermatology.",institutionString:null,institution:{name:"Sichuan University",institutionURL:null,country:{name:"China"}}},editorTwo:null,editorThree:null},{id:"5",title:"Parasitic Infectious Diseases",coverUrl:"https://cdn.intechopen.com/series_topics/covers/5.jpg",isOpenForSubmission:!0,annualVolume:11401,editor:{id:"67907",title:"Dr.",name:"Amidou",middleName:null,surname:"Samie",slug:"amidou-samie",fullName:"Amidou Samie",profilePictureURL:"https://mts.intechopen.com/storage/users/67907/images/system/67907.jpg",biography:"Dr. Amidou Samie is an Associate Professor of Microbiology at the University of Venda, in South Africa, where he graduated for his PhD in May 2008. He joined the Department of Microbiology the same year and has been giving lectures on topics covering parasitology, immunology, molecular biology and industrial microbiology. He is currently a rated researcher by the National Research Foundation of South Africa at category C2. He has published widely in the field of infectious diseases and has overseen several MSc’s and PhDs. His research activities mostly cover topics on infectious diseases from epidemiology to control. His particular interest lies in the study of intestinal protozoan parasites and opportunistic infections among HIV patients as well as the potential impact of childhood diarrhoea on growth and child development. He also conducts research on water-borne diseases and water quality and is involved in the evaluation of point-of-use water treatment technologies using silver and copper nanoparticles in collaboration with the University of Virginia, USA. He also studies the use of medicinal plants for the control of infectious diseases as well as antimicrobial drug resistance.",institutionString:null,institution:{name:"University of Venda",institutionURL:null,country:{name:"South Africa"}}},editorTwo:null,editorThree:null},{id:"6",title:"Viral Infectious Diseases",coverUrl:"https://cdn.intechopen.com/series_topics/covers/6.jpg",isOpenForSubmission:!0,annualVolume:11402,editor:{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",biography:"Professor Dr. Shailendra K. Saxena is a vice dean and professor at King George's Medical University, Lucknow, India. His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research work has been published in various high-impact factor journals (Science, PNAS, Nature Medicine) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. Dr. Saxena is a fellow of various international societies/academies including the Royal College of Pathologists, United Kingdom; Royal Society of Medicine, London; Royal Society of Biology, United Kingdom; Royal Society of Chemistry, London; and Academy of Translational Medicine Professionals, Austria. He was named a Global Leader in Science by The Scientist. He is also an international opinion leader/expert in vaccination for Japanese encephalitis by IPIC (UK).",institutionString:"King George's Medical University",institution:{name:"King George's Medical University",institutionURL:null,country:{name:"India"}}},editorTwo:null,editorThree:null}]},overviewPageOFChapters:{paginationCount:58,paginationItems:[{id:"81961",title:"Antioxidants as an Adjuncts to Periodontal Therapy",doi:"10.5772/intechopen.105016",signatures:"Sura Dakhil Jassim and Ali Abbas Abdulkareem",slug:"antioxidants-as-an-adjuncts-to-periodontal-therapy",totalDownloads:3,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Dental Trauma",coverURL:"https://cdn.intechopen.com/books/images_new/11567.jpg",subseries:{id:"2",title:"Prosthodontics and Implant Dentistry"}}},{id:"82357",title:"Caries Management Aided by Fluorescence-Based Devices",doi:"10.5772/intechopen.105567",signatures:"Atena Galuscan, Daniela Jumanca and Aurora Doris Fratila",slug:"caries-management-aided-by-fluorescence-based-devices",totalDownloads:4,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Dental Caries - The Selection of Restoration Methods and Restorative Materials",coverURL:"https://cdn.intechopen.com/books/images_new/11565.jpg",subseries:{id:"1",title:"Oral Health"}}},{id:"81894",title:"Diet and Nutrition and Their Relationship with Early Childhood Dental Caries",doi:"10.5772/intechopen.105123",signatures:"Luanna Gonçalves Ferreira, Giuliana de Campos Chaves Lamarque and Francisco Wanderley Garcia Paula-Silva",slug:"diet-and-nutrition-and-their-relationship-with-early-childhood-dental-caries",totalDownloads:11,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Dental Caries - The Selection of Restoration Methods and Restorative Materials",coverURL:"https://cdn.intechopen.com/books/images_new/11565.jpg",subseries:{id:"1",title:"Oral Health"}}},{id:"81595",title:"Prosthetic Concepts in Dental Implantology",doi:"10.5772/intechopen.104725",signatures:"Ivica Pelivan",slug:"prosthetic-concepts-in-dental-implantology",totalDownloads:27,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Current Concepts in Dental Implantology - From Science to Clinical Research",coverURL:"https://cdn.intechopen.com/books/images_new/10808.jpg",subseries:{id:"2",title:"Prosthodontics and Implant Dentistry"}}}]},overviewPagePublishedBooks:{paginationCount:8,paginationItems:[{type:"book",id:"6668",title:"Dental Caries",subtitle:"Diagnosis, Prevention and Management",coverURL:"https://cdn.intechopen.com/books/images_new/6668.jpg",slug:"dental-caries-diagnosis-prevention-and-management",publishedDate:"September 19th 2018",editedByType:"Edited by",bookSignature:"Zühre Akarslan",hash:"b0f7667770a391f772726c3013c1b9ba",volumeInSeries:1,fullTitle:"Dental Caries - Diagnosis, Prevention and Management",editors:[{id:"171887",title:"Prof.",name:"Zühre",middleName:null,surname:"Akarslan",slug:"zuhre-akarslan",fullName:"Zühre Akarslan",profilePictureURL:"https://mts.intechopen.com/storage/users/171887/images/system/171887.jpg",biography:"Zühre Akarslan was born in 1977 in Cyprus. She graduated from Gazi University Faculty of Dentistry, Ankara, Turkey in 2000. \r\nLater she received her Ph.D. degree from the Oral Diagnosis and Radiology Department; which was recently renamed as Oral and Dentomaxillofacial Radiology, from the same university. \r\nShe is working as a full-time Associate Professor and is a lecturer and an academic researcher. \r\nHer expertise areas are dental caries, cancer, dental fear and anxiety, gag reflex in dentistry, oral medicine, and dentomaxillofacial radiology.",institutionString:"Gazi University",institution:{name:"Gazi University",institutionURL:null,country:{name:"Turkey"}}}]},{type:"book",id:"7139",title:"Current Approaches in Orthodontics",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7139.jpg",slug:"current-approaches-in-orthodontics",publishedDate:"April 10th 2019",editedByType:"Edited by",bookSignature:"Belma Işık Aslan and Fatma Deniz Uzuner",hash:"2c77384eeb748cf05a898d65b9dcb48a",volumeInSeries:2,fullTitle:"Current Approaches in Orthodontics",editors:[{id:"42847",title:"Dr.",name:"Belma",middleName:null,surname:"Işik Aslan",slug:"belma-isik-aslan",fullName:"Belma Işik Aslan",profilePictureURL:"https://mts.intechopen.com/storage/users/42847/images/system/42847.jpg",biography:"Dr. Belma IşIk Aslan was born in 1976 in Ankara-TURKEY. After graduating from TED Ankara College in 1994, she attended to Gazi University, Faculty of Dentistry in Ankara. She completed her PhD in orthodontic education at Gazi University between 1999-2005. Dr. Işık Aslan stayed at the Providence Hospital Craniofacial Institude and Reconstructive Surgery in Michigan, USA for three months as an observer. She worked as a specialist doctor at Gazi University, Dentistry Faculty, Department of Orthodontics between 2005-2014. She was appointed as associate professor in January, 2014 and as professor in 2021. Dr. Işık Aslan still works as an instructor at the same faculty. She has published a total of 35 articles, 10 book chapters, 39 conference proceedings both internationally and nationally. Also she was the academic editor of the international book 'Current Advances in Orthodontics'. She is a member of the Turkish Orthodontic Society and Turkish Cleft Lip and Palate Society. She is married and has 2 children. Her knowledge of English is at an advanced level.",institutionString:"Gazi University Dentistry Faculty Department of Orthodontics",institution:null}]},{type:"book",id:"7572",title:"Trauma in Dentistry",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7572.jpg",slug:"trauma-in-dentistry",publishedDate:"July 3rd 2019",editedByType:"Edited by",bookSignature:"Serdar Gözler",hash:"7cb94732cfb315f8d1e70ebf500eb8a9",volumeInSeries:3,fullTitle:"Trauma in Dentistry",editors:[{id:"204606",title:"Dr.",name:"Serdar",middleName:null,surname:"Gözler",slug:"serdar-gozler",fullName:"Serdar Gözler",profilePictureURL:"https://mts.intechopen.com/storage/users/204606/images/system/204606.jpeg",biography:"Dr. Serdar Gözler has completed his undergraduate studies at the Marmara University Faculty of Dentistry in 1978, followed by an assistantship in the Prosthesis Department of Dicle University Faculty of Dentistry. Starting his PhD work on non-resilient overdentures with Assoc. Prof. Hüsnü Yavuzyılmaz, he continued his studies with Prof. Dr. Gürbüz Öztürk of Istanbul University Faculty of Dentistry Department of Prosthodontics, this time on Gnatology. He attended training programs on occlusion, neurology, neurophysiology, EMG, radiology and biostatistics. In 1982, he presented his PhD thesis \\Gerber and Lauritzen Occlusion Analysis Techniques: Diagnosis Values,\\ at Istanbul University School of Dentistry, Department of Prosthodontics. As he was also working with Prof. Senih Çalıkkocaoğlu on The Physiology of Chewing at the same time, Gözler has written a chapter in Çalıkkocaoğlu\\'s book \\Complete Prostheses\\ entitled \\The Place of Neuromuscular Mechanism in Prosthetic Dentistry.\\ The book was published five times since by the Istanbul University Publications. Having presented in various conferences about occlusion analysis until 1998, Dr. Gözler has also decided to use the T-Scan II occlusion analysis method. Having been personally trained by Dr. Robert Kerstein on this method, Dr. Gözler has been lecturing on the T-Scan Occlusion Analysis Method in conferences both in Turkey and abroad. Dr. Gözler has various articles and presentations on Digital Occlusion Analysis methods. He is now Head of the TMD Clinic at Prosthodontic Department of Faculty of Dentistry , Istanbul Aydın University , Turkey.",institutionString:"Istanbul Aydin University",institution:{name:"Istanbul Aydın University",institutionURL:null,country:{name:"Turkey"}}}]},{type:"book",id:"7060",title:"Gingival Disease",subtitle:"A Professional Approach for Treatment and Prevention",coverURL:"https://cdn.intechopen.com/books/images_new/7060.jpg",slug:"gingival-disease-a-professional-approach-for-treatment-and-prevention",publishedDate:"October 23rd 2019",editedByType:"Edited by",bookSignature:"Alaa Eddin Omar Al Ostwani",hash:"b81d39988cba3a3cf746c1616912cf41",volumeInSeries:4,fullTitle:"Gingival Disease - A Professional Approach for Treatment and Prevention",editors:[{id:"240870",title:"Ph.D.",name:"Alaa Eddin Omar",middleName:null,surname:"Al Ostwani",slug:"alaa-eddin-omar-al-ostwani",fullName:"Alaa Eddin Omar Al Ostwani",profilePictureURL:"https://mts.intechopen.com/storage/users/240870/images/system/240870.jpeg",biography:"Dr. Al Ostwani Alaa Eddin Omar received his Master in dentistry from Damascus University in 2010, and his Ph.D. in Pediatric Dentistry from Damascus University in 2014. Dr. Al Ostwani is an assistant professor and faculty member at IUST University since 2014. \nDuring his academic experience, he has received several awards including the scientific research award from the Union of Arab Universities, the Syrian gold medal and the international gold medal for invention and creativity. Dr. Al Ostwani is a Member of the International Association of Dental Traumatology and the Syrian Society for Research and Preventive Dentistry since 2017. 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He also obtained an MSc in Molecular and Genetic Medicine, and a Ph.D. in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also completed a short-term fellowship in Pediatric Clinical Immunology and Bone Marrow Transplantation at Newcastle General Hospital, England. Dr. Rezaei is a Full Professor of Immunology and Vice Dean of International Affairs and Research, at the School of Medicine, Tehran University of Medical Sciences, and the co-founder and head of the Research Center for Immunodeficiencies. He is also the founding president of the Universal Scientific Education and Research Network (USERN). Dr. Rezaei has directed more than 100 research projects and has designed and participated in several international collaborative projects. He is an editor, editorial assistant, or editorial board member of more than forty international journals. He has edited more than 50 international books, presented more than 500 lectures/posters in congresses/meetings, and published more than 1,100 scientific papers in international journals.",institutionString:"Tehran University of Medical Sciences",institution:{name:"Tehran University of Medical Sciences",country:{name:"Iran"}}},{id:"180733",title:"Dr.",name:"Jean",middleName:null,surname:"Engohang-Ndong",slug:"jean-engohang-ndong",fullName:"Jean Engohang-Ndong",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/180733/images/system/180733.png",biography:"Dr. Jean Engohang-Ndong was born and raised in Gabon. After obtaining his Associate Degree of Science at the University of Science and Technology of Masuku, Gabon, he continued his education in France where he obtained his BS, MS, and Ph.D. in Medical Microbiology. He worked as a post-doctoral fellow at the Public Health Research Institute (PHRI), Newark, NJ for four years before accepting a three-year faculty position at Brigham Young University-Hawaii. Dr. Engohang-Ndong is a tenured faculty member with the academic rank of Full Professor at Kent State University, Ohio, where he teaches a wide range of biological science courses and pursues his research in medical and environmental microbiology. Recently, he expanded his research interest to epidemiology and biostatistics of chronic diseases in Gabon.",institutionString:"Kent State University",institution:{name:"Kent State University",country:{name:"United States of America"}}},{id:"188773",title:"Prof.",name:"Emmanuel",middleName:null,surname:"Drouet",slug:"emmanuel-drouet",fullName:"Emmanuel Drouet",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/188773/images/system/188773.png",biography:"Emmanuel Drouet, PharmD, is a Professor of Virology at the Faculty of Pharmacy, the University Grenoble-Alpes, France. As a head scientist at the Institute of Structural Biology in Grenoble, Dr. Drouet’s research investigates persisting viruses in humans (RNA and DNA viruses) and the balance with our host immune system. He focuses on these viruses’ effects on humans (both their impact on pathology and their symbiotic relationships in humans). He has an excellent track record in the herpesvirus field, and his group is engaged in clinical research in the field of Epstein-Barr virus diseases. He is the editor of the online Encyclopedia of Environment and he coordinates the Universal Health Coverage education program for the BioHealth Computing Schools of the European Institute of Science.",institutionString:null,institution:{name:"Grenoble Alpes University",country:{name:"France"}}},{id:"131400",title:"Prof.",name:"Alfonso J.",middleName:null,surname:"Rodriguez-Morales",slug:"alfonso-j.-rodriguez-morales",fullName:"Alfonso J. Rodriguez-Morales",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/131400/images/system/131400.png",biography:"Dr. Rodriguez-Morales is an expert in tropical and emerging diseases, particularly zoonotic and vector-borne diseases (especially arboviral diseases). He is the president of the Travel Medicine Committee of the Pan-American Infectious Diseases Association (API), as well as the president of the Colombian Association of Infectious Diseases (ACIN). He is a member of the Committee on Tropical Medicine, Zoonoses, and Travel Medicine of ACIN. He is a vice-president of the Latin American Society for Travel Medicine (SLAMVI) and a Member of the Council of the International Society for Infectious Diseases (ISID). Since 2014, he has been recognized as a Senior Researcher, at the Ministry of Science of Colombia. He is a professor at the Faculty of Medicine of the Fundacion Universitaria Autonoma de las Americas, in Pereira, Risaralda, Colombia. He is an External Professor, Master in Research on Tropical Medicine and International Health, Universitat de Barcelona, Spain. He is also a professor at the Master in Clinical Epidemiology and Biostatistics, Universidad Científica del Sur, Lima, Peru. In 2021 he has been awarded the “Raul Isturiz Award” Medal of the API. Also, in 2021, he was awarded with the “Jose Felix Patiño” Asclepius Staff Medal of the Colombian Medical College, due to his scientific contributions to COVID-19 during the pandemic. He is currently the Editor in Chief of the journal Travel Medicine and Infectious Diseases. His Scopus H index is 47 (Google Scholar H index, 68).",institutionString:"Institución Universitaria Visión de las Américas, Colombia",institution:null},{id:"332819",title:"Dr.",name:"Chukwudi Michael",middleName:"Michael",surname:"Egbuche",slug:"chukwudi-michael-egbuche",fullName:"Chukwudi Michael Egbuche",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/332819/images/14624_n.jpg",biography:"I an Dr. Chukwudi Michael Egbuche. I am a Senior Lecturer in the Department of Parasitology and Entomology, Nnamdi Azikiwe University, Awka.",institutionString:null,institution:{name:"Nnamdi Azikiwe University",country:{name:"Nigeria"}}},{id:"284232",title:"Mr.",name:"Nikunj",middleName:"U",surname:"Tandel",slug:"nikunj-tandel",fullName:"Nikunj Tandel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/284232/images/8275_n.jpg",biography:'Mr. Nikunj Tandel has completed his Master\'s degree in Biotechnology from VIT University, India in the year of 2012. He is having 8 years of research experience especially in the field of malaria epidemiology, immunology, and nanoparticle-based drug delivery system against the infectious diseases, autoimmune disorders and cancer. He has worked for the NIH funded-International Center of Excellence in Malaria Research project "Center for the study of complex malaria in India (CSCMi)" in collaboration with New York University. The preliminary objectives of the study are to understand and develop the evidence-based tools and interventions for the control and prevention of malaria in different sites of the INDIA. Alongside, with the help of next-generation genomics study, the team has studied the antimalarial drug resistance in India. Further, he has extended his research in the development of Humanized mice for the study of liver-stage malaria and identification of molecular marker(s) for the Artemisinin resistance. At present, his research focuses on understanding the role of B cells in the activation of CD8+ T cells in malaria. Received the CSIR-SRF (Senior Research Fellow) award-2018, FIMSA (Federation of Immunological Societies of Asia-Oceania) Travel Bursary award to attend the IUIS-IIS-FIMSA Immunology course-2019',institutionString:"Nirma University",institution:{name:"Nirma University",country:{name:"India"}}},{id:"334383",title:"Ph.D.",name:"Simone",middleName:"Ulrich",surname:"Ulrich Picoli",slug:"simone-ulrich-picoli",fullName:"Simone Ulrich Picoli",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/334383/images/15919_n.jpg",biography:"Graduated in Pharmacy from Universidade Luterana do Brasil (1999), Master in Agricultural and Environmental Microbiology from Federal University of Rio Grande do Sul (2002), Specialization in Clinical Microbiology from Universidade de São Paulo, USP (2007) and PhD in Sciences in Gastroenterology and Hepatology (2012). She is currently an Adjunct Professor at Feevale University in Medicine and Biomedicine courses and a permanent professor of the Academic Master\\'s Degree in Virology. She has experience in the field of Microbiology, with an emphasis on Bacteriology, working mainly on the following topics: bacteriophages, bacterial resistance, clinical microbiology and food microbiology.",institutionString:null,institution:{name:"Universidade Feevale",country:{name:"Brazil"}}},{id:"229220",title:"Dr.",name:"Amjad",middleName:"Islam",surname:"Aqib",slug:"amjad-aqib",fullName:"Amjad Aqib",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/229220/images/system/229220.png",biography:"Dr. Amjad Islam Aqib obtained a DVM and MSc (Hons) from University of Agriculture Faisalabad (UAF), Pakistan, and a PhD from the University of Veterinary and Animal Sciences Lahore, Pakistan. Dr. Aqib joined the Department of Clinical Medicine and Surgery at UAF for one year as an assistant professor where he developed a research laboratory designated for pathogenic bacteria. Since 2018, he has been Assistant Professor/Officer in-charge, Department of Medicine, Manager Research Operations and Development-ORIC, and President One Health Club at Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Pakistan. He has nearly 100 publications to his credit. His research interests include epidemiological patterns and molecular analysis of antimicrobial resistance and modulation and vaccine development against animal pathogens of public health concern.",institutionString:"Cholistan University of Veterinary and Animal Sciences",institution:null},{id:"62900",title:"Prof.",name:"Fethi",middleName:null,surname:"Derbel",slug:"fethi-derbel",fullName:"Fethi Derbel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/62900/images/system/62900.jpeg",biography:"Professor Fethi Derbel was born in 1960 in Tunisia. He received his medical degree from the Sousse Faculty of Medicine at Sousse, University of Sousse, Tunisia. He completed his surgical residency in General Surgery at the University Hospital Farhat Hached of Sousse and was a member of the Unit of Liver Transplantation in the University of Rennes, France. He then worked in the Department of Surgery at the Sahloul University Hospital in Sousse. Professor Derbel is presently working at the Clinique les Oliviers, Sousse, Tunisia. His hospital activities are mostly concerned with laparoscopic, colorectal, pancreatic, hepatobiliary, and gastric surgery. He is also very interested in hernia surgery and performs ventral hernia repairs and inguinal hernia repairs. He has been a member of the GREPA and Tunisian Hernia Society (THS). During his residency, he managed patients suffering from diabetic foot, and he was very interested in this pathology. For this reason, he decided to coordinate a book project dealing with the diabetic foot. Professor Derbel has published many articles in journals and collaborates intensively with IntechOpen Access Publisher as an editor.",institutionString:"Clinique les Oliviers",institution:null},{id:"300144",title:"Dr.",name:"Meriem",middleName:null,surname:"Braiki",slug:"meriem-braiki",fullName:"Meriem Braiki",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/300144/images/system/300144.jpg",biography:"Dr. Meriem Braiki is a specialist in pediatric surgeon from Tunisia. She was born in 1985. She received her medical degree from the University of Medicine at Sousse, Tunisia. She achieved her surgical residency training periods in Pediatric Surgery departments at University Hospitals in Monastir, Tunis and France.\r\nShe is currently working at the Pediatric surgery department, Sidi Bouzid Hospital, Tunisia. Her hospital activities are mostly concerned with laparoscopic, parietal, urological and digestive surgery. She has published several articles in diffrent journals.",institutionString:"Sidi Bouzid Regional Hospital",institution:null},{id:"229481",title:"Dr.",name:"Erika M.",middleName:"Martins",surname:"de Carvalho",slug:"erika-m.-de-carvalho",fullName:"Erika M. de Carvalho",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/229481/images/6397_n.jpg",biography:null,institutionString:null,institution:{name:"Oswaldo Cruz Foundation",country:{name:"Brazil"}}},{id:"186537",title:"Prof.",name:"Tonay",middleName:null,surname:"Inceboz",slug:"tonay-inceboz",fullName:"Tonay Inceboz",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/186537/images/system/186537.jfif",biography:"I was graduated from Ege University of Medical Faculty (Turkey) in 1988 and completed his Med. PhD degree in Medical Parasitology at the same university. I became an Associate Professor in 2008 and Professor in 2014. I am currently working as a Professor at the Department of Medical Parasitology at Dokuz Eylul University, Izmir, Turkey.\n\nI have given many lectures, presentations in different academic meetings. I have more than 60 articles in peer-reviewed journals, 18 book chapters, 1 book editorship.\n\nMy research interests are Echinococcus granulosus, Echinococcus multilocularis (diagnosis, life cycle, in vitro and in vivo cultivation), and Trichomonas vaginalis (diagnosis, PCR, and in vitro cultivation).",institutionString:"Dokuz Eylül University",institution:{name:"Dokuz Eylül University",country:{name:"Turkey"}}},{id:"71812",title:"Prof.",name:"Hanem Fathy",middleName:"Fathy",surname:"Khater",slug:"hanem-fathy-khater",fullName:"Hanem Fathy Khater",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/71812/images/1167_n.jpg",biography:"Prof. Khater is a Professor of Parasitology at Benha University, Egypt. She studied for her doctoral degree, at the Department of Entomology, College of Agriculture, Food and Natural Resources, University of Missouri, Columbia, USA. She has completed her Ph.D. degrees in Parasitology in Egypt, from where she got the award for “the best scientific Ph.D. dissertation”. She worked at the School of Biological Sciences, Bristol, England, the UK in controlling insects of medical and veterinary importance as a grant from Newton Mosharafa, the British Council. Her research is focused on searching of pesticides against mosquitoes, house flies, lice, green bottle fly, camel nasal botfly, soft and hard ticks, mites, and the diamondback moth as well as control of several parasites using safe and natural materials to avoid drug resistances and environmental contamination.",institutionString:null,institution:{name:"Banha University",country:{name:"Egypt"}}},{id:"99780",title:"Prof.",name:"Omolade",middleName:"Olayinka",surname:"Okwa",slug:"omolade-okwa",fullName:"Omolade Okwa",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/99780/images/system/99780.jpg",biography:"Omolade Olayinka Okwa is presently a Professor of Parasitology at Lagos State University, Nigeria. She has a PhD in Parasitology (1997), an MSc in Cellular Parasitology (1992), and a BSc (Hons) Zoology (1990) all from the University of Ibadan, Nigeria. She teaches parasitology at the undergraduate and postgraduate levels. She was a recipient of a Commonwealth fellowship supported by British Council tenable at the Centre for Entomology and Parasitology (CAEP), Keele University, United Kingdom between 2004 and 2005. She was awarded an Honorary Visiting Research Fellow at the same university from 2005 to 2007. \nShe has been an external examiner to the Department of Veterinary Microbiology and Parasitology, University of Ibadan, MSc programme between 2010 and 2012. She is a member of the Nigerian Society of Experimental Biology (NISEB), Parasitology and Public Health Society of Nigeria (PPSN), Science Association of Nigeria (SAN), Zoological Society of Nigeria (ZSN), and is Vice Chairperson of the Organisation of Women in Science (OWSG), LASU chapter. She served as Head of Department of Zoology and Environmental Biology, Lagos State University from 2007 to 2010 and 2014 to 2016. She is a reviewer for several local and international journals such as Unilag Journal of Science, Libyan Journal of Medicine, Journal of Medicine and Medical Sciences, and Annual Research and Review in Science. \nShe has authored 45 scientific research publications in local and international journals, 8 scientific reviews, 4 books, and 3 book chapters, which includes the books “Malaria Parasites” and “Malaria” which are IntechOpen access publications.",institutionString:"Lagos State University",institution:{name:"Lagos State University",country:{name:"Nigeria"}}},{id:"273100",title:"Dr.",name:"Vijay",middleName:null,surname:"Gayam",slug:"vijay-gayam",fullName:"Vijay Gayam",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/273100/images/system/273100.jpeg",biography:"Dr. Vijay Bhaskar Reddy Gayam is currently practicing as an internist at Interfaith Medical Center in Brooklyn, New York, USA. He is also a Clinical Assistant Professor at the SUNY Downstate University Hospital and Adjunct Professor of Medicine at the American University of Antigua. He is a holder of an M.B.B.S. degree bestowed to him by Osmania Medical College and received his M.D. at Interfaith Medical Center. His career goals thus far have heavily focused on direct patient care, medical education, and clinical research. He currently serves in two leadership capacities; Assistant Program Director of Medicine at Interfaith Medical Center and as a Councilor for the American\r\nFederation for Medical Research. As a true academician and researcher, he has more than 50 papers indexed in international peer-reviewed journals. He has also presented numerous papers in multiple national and international scientific conferences. His areas of research interest include general internal medicine, gastroenterology and hepatology. He serves as an editor, editorial board member and reviewer for multiple international journals. His research on Hepatitis C has been very successful and has led to multiple research awards, including the 'Equity in Prevention and Treatment Award” from the New York Department of Health Viral Hepatitis Symposium (2018) and the 'Presidential Poster Award” awarded to him by the American College of Gastroenterology (2018). He was also awarded 'Outstanding Clinician in General Medicine” by Venus International Foundation for his extensive research expertise and services, perform over and above the standard expected in the advancement of healthcare, patient safety and quality of care.",institutionString:"Interfaith Medical Center",institution:{name:"Interfaith Medical Center",country:{name:"United States of America"}}},{id:"93517",title:"Dr.",name:"Clement",middleName:"Adebajo",surname:"Meseko",slug:"clement-meseko",fullName:"Clement Meseko",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/93517/images/system/93517.jpg",biography:"Dr. Clement Meseko obtained DVM and PhD degree in Veterinary Medicine and Virology respectively. He has worked for over 20 years in both private and public sectors including the academia, contributing to knowledge and control of infectious disease. Through the application of epidemiological skill, classical and molecular virological skills, he investigates viruses of economic and public health importance for the mitigation of the negative impact on people, animal and the environment in the context of Onehealth. \r\nDr. Meseko’s field experience on animal and zoonotic diseases and pathogen dynamics at the human-animal interface over the years shaped his carrier in research and scientific inquiries. He has been part of the investigation of Highly Pathogenic Avian Influenza incursions in sub Saharan Africa and monitors swine Influenza (Pandemic influenza Virus) agro-ecology and potential for interspecies transmission. He has authored and reviewed a number of journal articles and book chapters.",institutionString:"National Veterinary Research Institute",institution:{name:"National Veterinary Research Institute",country:{name:"Nigeria"}}},{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",biography:"Professor Dr. Shailendra K. Saxena is a vice dean and professor at King George's Medical University, Lucknow, India. His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. 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Many parasitic diseases are classified as neglected tropical diseases because they have received minimal funding over recent years and, in many cases, are under-reported despite the critical role they play in morbidity and mortality among human and animal hosts. The current topic, Parasitic Infectious Diseases, in the Infectious Diseases Series aims to publish studies on the systematics, epidemiology, molecular biology, genomics, pathogenesis, genetics, and clinical significance of parasitic diseases from blood borne to intestinal parasites as well as zoonotic parasites. We hope to cover all aspects of parasitic diseases to provide current and relevant research data on these very important diseases. In the current atmosphere of the Coronavirus pandemic, communities around the world, particularly those in different underdeveloped areas, are faced with the growing challenges of the high burden of parasitic diseases. At the same time, they are faced with the Covid-19 pandemic leading to what some authors have called potential syndemics that might worsen the outcome of such infections. Therefore, it is important to conduct studies that examine parasitic infections in the context of the coronavirus pandemic for the benefit of all communities to help foster more informed decisions for the betterment of human and animal health.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/5.jpg",keywords:"Blood Borne Parasites, Intestinal Parasites, Protozoa, Helminths, Arthropods, Water Born Parasites, Epidemiology, Molecular Biology, Systematics, Genomics, Proteomics, Ecology"},{id:"6",title:"Viral Infectious Diseases",scope:"The Viral Infectious Diseases Book Series aims to provide a comprehensive overview of recent research trends and discoveries in various viral infectious diseases emerging around the globe. The emergence of any viral disease is hard to anticipate, which often contributes to death. A viral disease can be defined as an infectious disease that has recently appeared within a population or exists in nature with the rapid expansion of incident or geographic range. This series will focus on various crucial factors related to emerging viral infectious diseases, including epidemiology, pathogenesis, host immune response, clinical manifestations, diagnosis, treatment, and clinical recommendations for managing viral infectious diseases, highlighting the recent issues with future directions for effective therapeutic strategies.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/6.jpg",keywords:"Novel Viruses, Virus Transmission, Virus Evolution, Molecular Virology, Control and Prevention, Virus-host Interaction"}],annualVolumeBook:{},thematicCollection:[{type:"book",id:"11672",title:"Chemokines Updates",subtitle:null,isOpenForSubmission:!0,hash:"c00855833476a514d37abf7c846e16e9",slug:null,bookSignature:"Prof. Murat Şentürk",coverURL:"https://cdn.intechopen.com/books/images_new/11672.jpg",editedByType:null,submissionDeadline:"May 6th 2022",editors:[{id:"14794",title:"Prof.",name:"Murat",middleName:null,surname:"Şentürk",slug:"murat-senturk",fullName:"Murat Şentürk",profilePictureURL:"https://mts.intechopen.com/storage/users/14794/images/system/14794.jpeg",biography:"Dr. Murat Şentürk obtained a baccalaureate degree in Chemistry in 2002, a master’s degree in Biochemistry in 2006, and a doctorate degree in Biochemistry in 2009 from Atatürk University, Turkey. Dr. Şentürk currently works as an professor of Biochemistry in the Department of Basic Pharmacy Sciences, Faculty of Pharmacy, Ağri Ibrahim Cecen University, Turkey. \nDr. Şentürk published over 120 scientific papers, reviews, and book chapters and presented several conferences to scientists. \nHis research interests span enzyme inhibitor or activator, protein expression, purification and characterization, drug design and synthesis, toxicology, and pharmacology. \nHis research work has focused on neurodegenerative diseases and cancer treatment. Dr. Şentürk serves as the editorial board member of several international journals.",institutionString:"Ağrı İbrahim Çeçen University",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"2",totalChapterViews:"0",totalEditedBooks:"1",institution:{name:"Ağrı İbrahim Çeçen University",institutionURL:null,country:{name:"Turkey"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}],selectedSeries:{title:"Infectious Diseases",id:"6"},selectedSubseries:null},seriesLanding:{item:{id:"11",title:"Biochemistry",doi:"10.5772/intechopen.72877",issn:"2632-0983",scope:"Biochemistry, the study of chemical transformations occurring within living organisms, impacts all areas of life sciences, from molecular crystallography and genetics to ecology, medicine, and population biology. Biochemistry examines macromolecules - proteins, nucleic acids, carbohydrates, and lipids – and their building blocks, structures, functions, and interactions. Much of biochemistry is devoted to enzymes, proteins that catalyze chemical reactions, enzyme structures, mechanisms of action and their roles within cells. Biochemistry also studies small signaling molecules, coenzymes, inhibitors, vitamins, and hormones, which play roles in life processes. Biochemical experimentation, besides coopting classical chemistry methods, e.g., chromatography, adopted new techniques, e.g., X-ray diffraction, electron microscopy, NMR, radioisotopes, and developed sophisticated microbial genetic tools, e.g., auxotroph mutants and their revertants, fermentation, etc. More recently, biochemistry embraced the ‘big data’ omics systems. Initial biochemical studies have been exclusively analytic: dissecting, purifying, and examining individual components of a biological system; in the apt words of Efraim Racker (1913 –1991), “Don’t waste clean thinking on dirty enzymes.” Today, however, biochemistry is becoming more agglomerative and comprehensive, setting out to integrate and describe entirely particular biological systems. The ‘big data’ metabolomics can define the complement of small molecules, e.g., in a soil or biofilm sample; proteomics can distinguish all the comprising proteins, e.g., serum; metagenomics can identify all the genes in a complex environment, e.g., the bovine rumen. This Biochemistry Series will address the current research on biomolecules and the emerging trends with great promise.",coverUrl:"https://cdn.intechopen.com/series/covers/11.jpg",latestPublicationDate:"June 29th, 2022",hasOnlineFirst:!0,numberOfOpenTopics:4,numberOfPublishedChapters:318,numberOfPublishedBooks:32,editor:{id:"31610",title:"Dr.",name:"Miroslav",middleName:null,surname:"Blumenberg",fullName:"Miroslav Blumenberg",profilePictureURL:"https://mts.intechopen.com/storage/users/31610/images/system/31610.jpg",biography:"Miroslav Blumenberg, Ph.D., was born in Subotica and received his BSc in Belgrade, Yugoslavia. He completed his Ph.D. at MIT in Organic Chemistry; he followed up his Ph.D. with two postdoctoral study periods at Stanford University. Since 1983, he has been a faculty member of the RO Perelman Department of Dermatology, NYU School of Medicine, where he is codirector of a training grant in cutaneous biology. Dr. Blumenberg’s research is focused on the epidermis, expression of keratin genes, transcription profiling, keratinocyte differentiation, inflammatory diseases and cancers, and most recently the effects of the microbiome on the skin. He has published more than 100 peer-reviewed research articles and graduated numerous Ph.D. and postdoctoral students.",institutionString:null,institution:{name:"New York University Langone Medical Center",institutionURL:null,country:{name:"United States of America"}}},subseries:[{id:"14",title:"Cell and Molecular Biology",keywords:"Omics (Transcriptomics; Proteomics; Metabolomics), Molecular Biology, Cell Biology, Signal Transduction and Regulation, Cell Growth and Differentiation, Apoptosis, Necroptosis, Ferroptosis, Autophagy, Cell Cycle, Macromolecules and Complexes, Gene Expression",scope:"The Cell and Molecular Biology topic within the IntechOpen Biochemistry Series aims to rapidly publish contributions on all aspects of cell and molecular biology, including aspects related to biochemical and genetic research (not only in humans but all living beings). We encourage the submission of manuscripts that provide novel and mechanistic insights that report significant advances in the fields. Topics include, but are not limited to: Advanced techniques of cellular and molecular biology (Molecular methodologies, imaging techniques, and bioinformatics); Biological activities at the molecular level; Biological processes of cell functions, cell division, senescence, maintenance, and cell death; Biomolecules interactions; Cancer; Cell biology; Chemical biology; Computational biology; Cytochemistry; Developmental biology; Disease mechanisms and therapeutics; DNA, and RNA metabolism; Gene functions, genetics, and genomics; Genetics; Immunology; Medical microbiology; Molecular biology; Molecular genetics; Molecular processes of cell and organelle dynamics; Neuroscience; Protein biosynthesis, degradation, and functions; Regulation of molecular interactions in a cell; Signalling networks and system biology; Structural biology; Virology and microbiology.",annualVolume:11410,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/14.jpg",editor:{id:"165627",title:"Dr.",name:"Rosa María",middleName:null,surname:"Martínez-Espinosa",fullName:"Rosa María Martínez-Espinosa",profilePictureURL:"https://mts.intechopen.com/storage/users/165627/images/system/165627.jpeg",institutionString:null,institution:{name:"University of Alicante",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"79367",title:"Dr.",name:"Ana Isabel",middleName:null,surname:"Flores",fullName:"Ana Isabel Flores",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRpIOQA0/Profile_Picture_1632418099564",institutionString:null,institution:{name:"Hospital Universitario 12 De Octubre",institutionURL:null,country:{name:"Spain"}}},{id:"328234",title:"Ph.D.",name:"Christian",middleName:null,surname:"Palavecino",fullName:"Christian Palavecino",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000030DhEhQAK/Profile_Picture_1628835318625",institutionString:null,institution:{name:"Central University of Chile",institutionURL:null,country:{name:"Chile"}}},{id:"186585",title:"Dr.",name:"Francisco Javier",middleName:null,surname:"Martin-Romero",fullName:"Francisco Javier Martin-Romero",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSB3HQAW/Profile_Picture_1631258137641",institutionString:null,institution:{name:"University of Extremadura",institutionURL:null,country:{name:"Spain"}}}]},{id:"15",title:"Chemical Biology",keywords:"Phenolic Compounds, Essential Oils, Modification of Biomolecules, Glycobiology, Combinatorial Chemistry, Therapeutic peptides, Enzyme Inhibitors",scope:"Chemical biology spans the fields of chemistry and biology involving the application of biological and chemical molecules and techniques. In recent years, the application of chemistry to biological molecules has gained significant interest in medicinal and pharmacological studies. This topic will be devoted to understanding the interplay between biomolecules and chemical compounds, their structure and function, and their potential applications in related fields. Being a part of the biochemistry discipline, the ideas and concepts that have emerged from Chemical Biology have affected other related areas. This topic will closely deal with all emerging trends in this discipline.",annualVolume:11411,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/15.jpg",editor:{id:"441442",title:"Dr.",name:"Şükrü",middleName:null,surname:"Beydemir",fullName:"Şükrü Beydemir",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003GsUoIQAV/Profile_Picture_1634557147521",institutionString:null,institution:{name:"Anadolu University",institutionURL:null,country:{name:"Turkey"}}},editorTwo:{id:"13652",title:"Prof.",name:"Deniz",middleName:null,surname:"Ekinci",fullName:"Deniz Ekinci",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYLT1QAO/Profile_Picture_1634557223079",institutionString:null,institution:{name:"Ondokuz Mayıs University",institutionURL:null,country:{name:"Turkey"}}},editorThree:null,editorialBoard:[{id:"219081",title:"Dr.",name:"Abdulsamed",middleName:null,surname:"Kükürt",fullName:"Abdulsamed Kükürt",profilePictureURL:"https://mts.intechopen.com/storage/users/219081/images/system/219081.png",institutionString:null,institution:{name:"Kafkas University",institutionURL:null,country:{name:"Turkey"}}},{id:"241413",title:"Dr.",name:"Azhar",middleName:null,surname:"Rasul",fullName:"Azhar Rasul",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRT1oQAG/Profile_Picture_1635251978933",institutionString:null,institution:{name:"Government College University, Faisalabad",institutionURL:null,country:{name:"Pakistan"}}},{id:"178316",title:"Ph.D.",name:"Sergey",middleName:null,surname:"Sedykh",fullName:"Sergey Sedykh",profilePictureURL:"https://mts.intechopen.com/storage/users/178316/images/system/178316.jfif",institutionString:null,institution:{name:"Novosibirsk State University",institutionURL:null,country:{name:"Russia"}}}]},{id:"17",title:"Metabolism",keywords:"Biomolecules Metabolism, Energy Metabolism, Metabolic Pathways, Key Metabolic Enzymes, Metabolic Adaptation",scope:"Metabolism is frequently defined in biochemistry textbooks as the overall process that allows living systems to acquire and use the free energy they need for their vital functions or the chemical processes that occur within a living organism to maintain life. Behind these definitions are hidden all the aspects of normal and pathological functioning of all processes that the topic ‘Metabolism’ will cover within the Biochemistry Series. Thus all studies on metabolism will be considered for publication.",annualVolume:11413,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/17.jpg",editor:{id:"138626",title:"Dr.",name:"Yannis",middleName:null,surname:"Karamanos",fullName:"Yannis Karamanos",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002g6Jv2QAE/Profile_Picture_1629356660984",institutionString:null,institution:{name:"Artois University",institutionURL:null,country:{name:"France"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"243049",title:"Dr.",name:"Anca",middleName:null,surname:"Pantea Stoian",fullName:"Anca Pantea Stoian",profilePictureURL:"https://mts.intechopen.com/storage/users/243049/images/system/243049.jpg",institutionString:null,institution:{name:"Carol Davila University of Medicine and Pharmacy",institutionURL:null,country:{name:"Romania"}}},{id:"203824",title:"Dr.",name:"Attilio",middleName:null,surname:"Rigotti",fullName:"Attilio Rigotti",profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institutionString:null,institution:{name:"Pontifical Catholic University of Chile",institutionURL:null,country:{name:"Chile"}}},{id:"300470",title:"Dr.",name:"Yanfei (Jacob)",middleName:null,surname:"Qi",fullName:"Yanfei (Jacob) Qi",profilePictureURL:"https://mts.intechopen.com/storage/users/300470/images/system/300470.jpg",institutionString:null,institution:{name:"Centenary Institute of Cancer Medicine and Cell Biology",institutionURL:null,country:{name:"Australia"}}}]},{id:"18",title:"Proteomics",keywords:"Mono- and Two-Dimensional Gel Electrophoresis (1-and 2-DE), Liquid Chromatography (LC), Mass Spectrometry/Tandem Mass Spectrometry (MS; MS/MS), Proteins",scope:"With the recognition that the human genome cannot provide answers to the etiology of a disorder, changes in the proteins expressed by a genome became a focus in research. Thus proteomics, an area of research that detects all protein forms expressed in an organism, including splice isoforms and post-translational modifications, is more suitable than genomics for a comprehensive understanding of the biochemical processes that govern life. The most common proteomics applications are currently in the clinical field for the identification, in a variety of biological matrices, of biomarkers for diagnosis and therapeutic intervention of disorders. From the comparison of proteomic profiles of control and disease or different physiological states, which may emerge, changes in protein expression can provide new insights into the roles played by some proteins in human pathologies. Understanding how proteins function and interact with each other is another goal of proteomics that makes this approach even more intriguing. Specialized technology and expertise are required to assess the proteome of any biological sample. Currently, proteomics relies mainly on mass spectrometry (MS) combined with electrophoretic (1 or 2-DE-MS) and/or chromatographic techniques (LC-MS/MS). MS is an excellent tool that has gained popularity in proteomics because of its ability to gather a complex body of information such as cataloging protein expression, identifying protein modification sites, and defining protein interactions. The Proteomics topic aims to attract contributions on all aspects of MS-based proteomics that, by pushing the boundaries of MS capabilities, may address biological problems that have not been resolved yet.",annualVolume:11414,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/18.jpg",editor:{id:"200689",title:"Prof.",name:"Paolo",middleName:null,surname:"Iadarola",fullName:"Paolo Iadarola",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSCl8QAG/Profile_Picture_1623568118342",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorTwo:{id:"201414",title:"Dr.",name:"Simona",middleName:null,surname:"Viglio",fullName:"Simona Viglio",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRKDHQA4/Profile_Picture_1630402531487",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorThree:null,editorialBoard:[{id:"72288",title:"Dr.",name:"Arli Aditya",middleName:null,surname:"Parikesit",fullName:"Arli Aditya Parikesit",profilePictureURL:"https://mts.intechopen.com/storage/users/72288/images/system/72288.jpg",institutionString:null,institution:{name:"Indonesia International Institute for Life Sciences",institutionURL:null,country:{name:"Indonesia"}}},{id:"40928",title:"Dr.",name:"Cesar",middleName:null,surname:"Lopez-Camarillo",fullName:"Cesar Lopez-Camarillo",profilePictureURL:"https://mts.intechopen.com/storage/users/40928/images/3884_n.png",institutionString:null,institution:{name:"Universidad Autónoma de la Ciudad de México",institutionURL:null,country:{name:"Mexico"}}},{id:"81926",title:"Dr.",name:"Shymaa",middleName:null,surname:"Enany",fullName:"Shymaa Enany",profilePictureURL:"https://mts.intechopen.com/storage/users/81926/images/system/81926.png",institutionString:"Suez Canal University",institution:{name:"Suez Canal University",institutionURL:null,country:{name:"Egypt"}}}]}]}},libraryRecommendation:{success:null,errors:{},institutions:[]},route:{name:"chapter.detail",path:"/chapters/843",hash:"",query:{},params:{id:"843"},fullPath:"/chapters/843",meta:{},from:{name:null,path:"/",hash:"",query:{},params:{},fullPath:"/",meta:{}}}},function(){var e;(e=document.currentScript||document.scripts[document.scripts.length-1]).parentNode.removeChild(e)}()