\r\n\tDegeneration of photoreceptors, the major light-sensing cells in the eye, is a primary cause of vision loss worldwide. Identifying the underlying causes surrounding photoreceptor cell death is dominant in order to develop new treatment strategies to prevent their loss. These pathologies can be roughly divided into those conditions that initially affect rod photoreceptors, such as retinitis pigmentosa, and those that initially affect cone photoreceptors, such as macular degeneration. Retinitis pigmentosa is a group of diseases in which a mutation in one of the large variety of genes causes death of rod photoreceptors. \r\n\tRetinal detachment and subsequent degeneration of the retina can lead to progressive visual decline due to photoreceptor cell death. Since photoreceptors are nondividing cells, their loss results in irreversible visual impairment even after successful retinal reattachment surgery. \r\n\tOxidative stress and free radical damage also impact on the photoreceptors and retinal pigmented epithelium cells in the ageing eye. Nevertheless, drug delivery to the neuroretina, and even more so to the retinal photoreceptors, still has inherent and important challenges that must be analyzed. \r\n\tThis book intends to provide the reader with a comprehensive overview of recent advances in Photoreceptors research. The book will cover the following topics:
\r\n
\r\n\t1. Structure And Function Of Photoreceptors \r\n\t2. Retinitis pigmentosa \r\n\t3. Macular degeneration \r\n\t4. Light-induced photoreceptor cell damage \r\n\t5. Pathologies associated to Photoreceptors \r\n\t6. Drug delivery to retinal photoreceptors
",isbn:null,printIsbn:"979-953-307-X-X",pdfIsbn:null,doi:null,price:0,priceEur:0,priceUsd:0,slug:null,numberOfPages:0,isOpenForSubmission:!1,isSalesforceBook:!1,hash:"6a73b3bad3f7278cabee8bd09a89d679",bookSignature:"Prof. Angel Catala",publishedDate:null,coverURL:"https://cdn.intechopen.com/books/images_new/8936.jpg",keywords:"photoreceptor, phototransduction, progressive vision loss, night blindness, age-related macular degeneration, basal laminar deposit, apoptosis, disulfide dimerization, genotype-phenotype correlation, inherited retinal dystrophy, liposomes, niosomes",numberOfDownloads:null,numberOfWosCitations:0,numberOfCrossrefCitations:0,numberOfDimensionsCitations:0,numberOfTotalCitations:0,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"August 27th 2019",dateEndSecondStepPublish:"September 17th 2019",dateEndThirdStepPublish:"November 16th 2019",dateEndFourthStepPublish:"February 4th 2020",dateEndFifthStepPublish:"April 4th 2020",remainingDaysToSecondStep:"3 years",secondStepPassed:!0,currentStepOfPublishingProcess:5,editedByType:null,kuFlag:!1,biosketch:null,coeditorOneBiosketch:null,coeditorTwoBiosketch:null,coeditorThreeBiosketch:null,coeditorFourBiosketch:null,coeditorFiveBiosketch:null,editors:[{id:"196544",title:"Prof.",name:"Angel",middleName:null,surname:"Catala",slug:"angel-catala",fullName:"Angel Catala",profilePictureURL:"https://mts.intechopen.com/storage/users/196544/images/system/196544.jpg",biography:"Angel Catalá studied chemistry at Universidad Nacional de La Plata, Argentina, where he received a Ph.D. in Chemistry (Biological Branch) in 1965. From 1964 to 1974, he worked as an Assistant in Biochemistry at the School of Medicine at the same university. From 1974 to 1976, he was a fellow of the National Institutes of Health (NIH) at the University of Connecticut, Health Center, USA. From 1985 to 2004, he served as a Full Professor of Biochemistry at the Universidad Nacional de La Plata. He is a member of the National Research Council (CONICET), Argentina, and the Argentine Society for Biochemistry and Molecular Biology (SAIB). His laboratory has been interested for many years in the lipid peroxidation of biological membranes from various tissues and different species. Dr. Catalá has directed twelve doctoral theses, published more than 100 papers in peer-reviewed journals, several chapters in books, and edited twelve books. He received awards at the 40th International Conference Biochemistry of Lipids 1999 in Dijon, France. 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Venkateswarlu",coverURL:"https://cdn.intechopen.com/books/images_new/371.jpg",editedByType:"Edited by",editors:[{id:"58592",title:"Dr.",name:"Arun",surname:"Shanker",slug:"arun-shanker",fullName:"Arun Shanker"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},chapter:{item:{type:"chapter",id:"78679",title:"Tracking Control of Unmanned Aerial Vehicle for Power Line Inspection",doi:"10.5772/intechopen.100067",slug:"tracking-control-of-unmanned-aerial-vehicle-for-power-line-inspection",body:'
1. Introduction
Electric power companies worldwide are obliged to guarantee disruptive electrical power supply. The power transmission facilities mainly include power lines, towers, and insulators. These facilities are exposed to thunderstorms, thermal deviations, ice, rain, pollutions like volcanic gases and sour rains: a severe environment that may lead to material fatigue, oxidation, and corrosion. Electric companies are required to inspect and maintain the power transmission equipment periodically. Ground patrols partially inspect these facilities, and, as shown in Figure 1, direct visual examination is carried out by skilled personnel climbing over de-energized power lines. As yet, visual inspection is time-expensive and labour-intensive. A common approach nowadays is to use helicopters equipped with high-resolution cameras, but in such inspection, helicopters cannot cover narrow mountainous regions due to regulatory constraints. According to the Statistical Report of the Federation of Electric Power Companies in Japan, the total length of high voltage power transmission lines in the country in 2010 is more than 100,000 km, and the number of power transmission towers is much more than 220,000 [1]. Most power transmission facilities in Japan are situated in mountainous regions with no ordinary roads, making the inspection time-consuming and costly.
Figure 1.
Power line inspection works.
Unmanned aerial vehicles (UAV) are a promising solution for power line inspection because of time and cost efficiency and because UAVs can approach and inspect energized lines safely. Hence, a significant amount of research is addressing this field. Many researchers have applied computer vision techniques for power transmission towers, and insulators recognition [2, 3, 4, 5, 6, 7, 8]. Image processing algorithms are also heavily employed to power lines recognition and tracking [2, 9, 10, 11, 12, 13, 14, 15, 16, 17]. However, in most of these studies, distance to the lines is not measured, and their robustness is challenging. In [2] a Region-Based Convolutional Neural Network (R-CNN) is used to localization of transmission towers, and their UAV navigation relies on real-time image processing. The authors of [2] claim that “It is the first time to navigate UAV simultaneously utilizing transmission towers and lines”. In [9, 15] after the quadrotor helicopter is navigated to the start point of inspection manually, the vehicle performs autonomous waypoint flight above power lines. Additionally, a Light Detection and Ranging (LiDAR) sensor detect and reconstruct the power line shape [15]. Nevertheless, such navigation may be applied to power distribution lines, but manual flight cannot be performed safely enough when there is a substantial distance to the inspection object. In [11] power transmission lines situated in a highly-populated area are successfully tracked in waypoint flight mode with an aerial speed of 8 m/s. Similar algorithms for power transmission line tracking using position-based visual servo controllers are developed in [10, 12, 13] and are evaluated through several simulations. In [16] an image-based visual servoing combined with a linear quadratic servo control is developed. Deep reinforcement learning is quite successfully applied to autonomous line tracking in [18]. However, network training is performed within a simulation environment, and the robustness of that approach in the real world remains a challenge. The distance to the power line in [18] is measured using a depth camera or stereo camera.
Because of the great significance of automated power lines inspection, power supply companies are rigorously approaching the problem, too [19, 20, 21, 22, 23]. However, as far as we know, UAVs are not yet deployed to inspect power line transmission facilities. Hydro-Québec [19] is developing a robot called LineRanger to inspect transmission line conductor bundles. The robot is directly attached to the power line bundle and automatically crosses obstacles like line separators and suspension insulators. LineRanger is equipped with a high-resolution camera and a LiDAR for vegetation monitoring. The system can cover several kilometers a day. They have also developed a similar robotic system called LineScout, capable of inspecting a single transmission line [20]. It can acquire visual information and measure the joints’ electrical resistance and monitor the corrosion level of the conductors. DJI M200 Series drones produced by DJI are effectively deployed for power line inspection mainly under manual operation [21]. Although manual vehicle guidance is not time-effective, such inspection is much better than the direct one. The University of KwaZulu-Natal is working with Eskom Holdings SOC Ltd. to develop a power line inspection robot [22], which can climb around jumpers and suspension clamps on a single power transmission line or ground wire. The Electric Power Research Institute (EPRI) is developing a transmission line inspection robot [23], known as “Ti,” that can be permanently installed to traverse about 130 km of transmission lines. The robot can transmit in real-time weather data, vegetation imaging, and detect any obstructions on lines. EPRI also worked with manufacturer RADēCO Inc. and Exyn Technologies to develop “an autonomous drone to inspect components in elevated hard-to-access areas, search for temperature anomalies, and collect dose rate surveys in radiological zones” [24]. With UAV’s Level 4 technology, the UAV can perform a free-flight exploration of complex spaces while collecting data from the environment [25, 26]. This technology will speed up the implementation of UAVs in the autonomous inspection.
This work presents a novel quadrotor-based system for power line inspection. An outline and some preliminary results of this research are presented in [27], but this paper describes the power line tracking algorithm and its effectiveness and applicability. The main contributions of this study are (1) the development of a quadrotor based system for autonomous inspection of electrical energy transmission and distribution assets. The presented in this paper system has almost Level 4 autonomy in the sense that it can perform flights beyond visual line of sight and without operator based navigation. (2) As far as we are concerned, this is the first time a quadrotor UAV is used in a real application for full autonomous inspection of power lines. (3) The developed system can be applied to almost any industrial multirotor helicopter able to carry the payload of sensors and cameras necessary for inspection.
The rest of the paper is organized as follows. Section 2 presents the quadrotor model used in this development. Section 3 describes the hardware and software configuration of the quadrotor system briefly. The quadrotor model described in Section 2 is evaluated in Section 4 and simulation and experimental results demonstrating the usability of the developed tracking system are depicted there. The last section concludes the paper and gives some plans for further expansion of this work.
2. Quadrotor helicopter dynamics and control
2.1 Quadrotor dynamics
The quadrotor configuration and its reference coordinate systems are shown in Figure 2. The vehicle model is acquired under the following assumptions:
The quadrotor construction is rigid and symmetrical.
The propellers are rigid.
The ground effect is neglected, and the centre of gravity of the vehicle lies at the origin of its body coordinate system.
Figure 2.
Quadrotor UAV body and world coordinate systems.
The world reference frame is On and the body fixed frame is Ob. The xb axis of body frame points at normal flight direction, yb is in starboard side, and zb axis is in descend direction. The absolute position of the quadrotor body frame pn=xnynznT is given by three coordinates of the center of mass in On, and its attitude is given by three Euler angles rb=ϕθψT standing for roll, pitch and yaw angles, respectively.
The dynamics of the quadrotor helicopter expressed in Newton–Euler notation [28, 29, 30, 31] as:
ṗn=vnE1
v̇n=m−1CbnFbE2
ṙb=ωbE3
ω̇b=J−1Mb+J−1ωb×Jωb,E4
where m is the mass of the quadrotor frame and Cbn is the rotation matrix to transform the body frame into world reference frame On. The quadrotor translational and rotational motions control is performed by properly changing the thrust FTi,i=1,..,4 of rotors. The thrust of the rotors varies by changing their angular speed. The rotor thrust is proportional to the square of the angular rotor speed:
FTi=CTωmi2,E5
where CT is a thrust coefficient, and the angular speed of the rotor is [28]:
ω̇mi=1JmkeRmUi−keωmi−ktFTi+Dωmi,i=1,..,4,E6
where Ui is the voltage applied to the motor, Jm is the moment of inertia of the armature and the propeller, Rm is the resistance of the armature coil, ke and kt are the electromotive force and torque constants, respectively, and D is the motor viscous friction constant.
The torque generated by the motor i is:
Mi=ktFTi=ktCTωmi2.E7
The total thrust Fz is:
Fz=∑i=14FTi,E8
and control torque vector produced by the four motors is:
where the viscous friction D in (6) is neglected. The frame control inputs become the motor drive voltages Ui.
2.2 Control scheme
The overall structure of the closed-loop control of the quadrotor frame is shown in Figure 3. The vehicle is an underactuated mechanical system with six degrees of freedom and only four control inputs. The controller consists of a set of cascaded PID controllers arranged in inner and outer loops. The inner loops control the attitude, yaw rate, and vertical velocity. The outer loop controls the altitude and heading. Both loops are designed similarly to those implemented in the actual quadrotor flight controller [33]. This control technique is called a time-scale separation [34] and works well when the inner loops are significantly faster than the outer ones. The MIXER block in Figure 3 forms the voltages applied to the motors:
3. Power line autonomous inspection system architecture
3.1 Hardware design
The hardware architecture of the quadrotor system is shown in Figure 4a. The power transmission lines are detected using a LiDAR pointing in a vertical direction. Measured distance to the power line by the same LiDAR is used to adjust the zoom and focus of the image acquisition camera. The obstacle avoidance algorithm uses an infrared Time-of-Flight (ToF) sensor having 360° range and pointing horizontally. Because the magnetic field generated by the power lines interferes with the internal compass of the flight controller, the heading of the vehicle is estimated through a moving baseline real-time kinematics (RTK) [35] technique. For safety reasons, a second GNSS module is added to the frame. A second camera pointing in the down direction performs the vegetation monitoring under the power line corridor. All sensors are connected to NVIDIA Jetson TX2 [36] companion computer, which controls the position of the vehicle via MAVLink protocol [37]. The real-time images from a first-person view (FPV) camera and the complete status of the quadrotor (position in the world and the local coordinate systems, battery level, GNSS status, magnetic field strength) are transmitted to the ground station computer in 1 s intervals for system monitoring. The wireless modem (SkyHopper PRO V [38]) performs all necessary communications between the quadrotor frame and the ground station. The aircraft is stabilized by a Pixhawk flight controller (FC) [39]. However, the altitude zb and lateral control xb during line tracking is performed using three outer loops realized on the companion computer as shown in Figure 4a. FC controls the forward speed with a reference command from the companion computer. The vision system estimates the yaw angle ψ. Figure 4b depicts the UAV appearance. The specifications of the quadrotor helicopter are given in Table 1.
Figure 4.
Hardware architecture and vehicle appearance. (a) Hardware architecture, (b) appearance of the quadrotor system.
The control software is realized in Python language, and most of it runs under Robot Operating System (ROS) [40]. The software consists of modules for sensor data acquisition and processing, camera control node, and node for sensor data transmission to the control process and the same time to the base station computer. The control process receives power line position measured by the LiDAR pointing in the down position in the body coordinate system, GNSS coordinates of the tower to be inspected, GNSS receiver status, battery status, and FC status. The control process uses three PID controllers for altitude and yaw control, as shown in Figure 4a. It performs path generation as well as almost all necessary processing for realizing a safe flight.
Even though the vehicle control software communicates with the sensor relating nodes, it runs thoroughly independent from the ROS processes for safety reasons. Because of this autonomy, the control process can bring the vehicle safely back to the home position even if the whole ROS crashes or all sensors except one of the GPS modules get out of order.
3.3 Power line tracking
The inspection process includes the following actions. As shown in Figure 5, after taking off at safe altitude, the vehicle approaches the start tower of the inspection path using a priori information about the tower world coordinates and its height. Then the electrical line subject to inspection is detected by the LiDAR pointing in a downward direction. Next, the vehicle is positioned above the wire at a distance allowing it to acquire good quality images. While keeping a constant distance to the power line, the quadrotor moves along it at a constant speed and acquires high-resolution images of the wire and the vegetation below. After reaching the last tower subject of inspection, the quadrotor returns safely to the home position.
Figure 5.
Power line tracking concept.
The autonomous inspection consists of the following steps:
Selection of the inspection target using a graphical user interface (GUI) running on the base station computer (see Figure 6).
Using a priori data about the tower position in the world coordinate system and its mechanical construction, the vehicle takes off to a safe altitude. It approaches the top of the tower using GNSS measurements.
Search of the power line subject of the inspection. The search is performed using LiDAR readings of the power line position.
Power line tracking control at a certain velocity and constant distance, based on the LiDAR measurements and same time performing continuous image acquisition and image processing for detection of rust and defects on the power line. An additional camera monitors the vegetation under the power line corridor.
After finishing the inspection, the UAV returns safely back to the home position.
Figure 6.
GUI for power line inspection. GW: ground wire, L: left, R: right, RTL: return to launch.
The GUI is used to send the inspection subject to the quadrotor companion computer before the beginning of the inspection. It also displays the UAV status during the flight and its position on the map. The power transmission towers are displayed on the same map, too. Preflight safety tests of the vehicle and the control software can also be invoked from the same GUI. After the beginning of the inspection, communication from the aircraft only is performed. Only the Return to Launch (RTL) command can be transmitted from the GUI.
The GUI in Figure 6 shows a setting for a ground wire (GW) inspection. Images of the ground wire can be acquired from above and from a slant direction. The subject shown in the figure is a transmission tower with two ground wires. The left-side wire is selected, and the images from the top above are to be acquired. Left or right side GWs can also be inspected from slant direction: “R-Left” means right-side wire to be scanned from the left-side, “R-Right” means right-side wire to be scanned from the right-side and so on.
Figure 7 shows the UAV during autonomous ground wire inspection. The image in Figure 7 is acquired by a camera mounted on a second aircraft.
Figure 7.
Quadrotor system during power line autonomous inspection.
4. Simulation and experimental results
4.1 Step response simulation and experiments
In this section, the quadrotor model (Eq. (19)) is validated by simulation and experiments. The UAV specification is shown in Table 1. The parameters of the quadrotor are shown in Table 2 and PID controller parameters are depicted in Table 3. In these experiments, the model and actual vehicle are moved along body coordinates system axes at a constant speed. The simulation and experimental responses are compared in Figure 8. Figure 8a, c, and e show the responses during up-down, forward-backward, and left–right flights. The simulation and experimental results are very similar, showing that the model presents the actual vehicle’s behavior well. It can be seen that the actual vehicle in up-down flights tends to increase the altitude slightly, and we suppose that might exist some problem in tuning the flight controller filter parameters, causing error in the estimation of the altitude. In Figure 8b, d, and f the body roll and pitch angles are drawn. It can be observed that angles ϕ and θ during simulation and experiments slightly differ. Therefore, we can conclude that the experimental results demonstrate the theoretical expectations.
Parameter
Value
Description
U[V]
25.0
Maximum input voltage
Rm[Ω]
0.013
Armature resistance
ke[s/rad]
0.0306
Back EMF coefficient
kt
1.0×10−4
Torque coefficient
Jm[kg⋅m2]
6.68×10−4
Rotor moment of inertia
CT0[N/rad2]
3.37×10−5
Thrust coefficient
m[kg]
7.0
Total weight
lm[m]
0.275
Motor distance to the center of UAV
Jx[kg⋅ m2]
0.637
Moment of inertia (x-axis)
Jy[kg⋅ m2]
0.637
Moment of inertia (y-axis)
Jz[kg⋅ m2]
0.52
Moment of inertia (z-axis)
Cd,Fx
0.167
Drag coefficient (x-axis)
Cd,Fy
0.167
Drag coefficient (y-axis)
Cd,Fz
0.059
Drag coefficient (z-axis)
Cd,Mx
0.059
Rotational drag coefficient (x-axis)
Cd,My
0.059
Rotational drag coefficient (y-axis)
Cd,Mz
0.167
Rotational drag coefficient (z-axis)
Table 2.
UAV parameters.
Controller
P
I
D
Speed vxb
0.225
0.225
0.02
Speed vyb
0.225
0.225
0.02
Speed vzb
25.0
5.0
0.0
Roll ϕ
70.0
25.0
10.0
Pitch θ
70.0
25.0
10.0
Yaw ψ
100.0
3.5
150
Position yb
0.15
0.0
0.05
Position zb
0.5
0.03
0.05
Table 3.
PID controllers parameters.
Figure 8.
Step response simulations and experiment results. (a) Up-down movement, (b) roll and pitch angles during up-down flight, (c) flight in forward and backward directions, (d) roll and pitch during forward and backward flight, (e) left and right movement, (f) roll and pitch during left and right flight.
4.2 Power line tracking simulation
In this section, simulation and experimental results during power line tracking are presented. The simulation setting is given in Figure 9. The simulation conditions are as follows:
At the beginning of the simulation, the initial position of the UAV is 6 m above and 1 m on the port side of the power line.
After position adjustment above the line for 10 s is done, the vehicle performs a wire tracking flight.
The position of the power line in the vehicle coordinate system during tracking is set to z=3m and y=0m.
Figure 9.
Setup for power line tracking simulations and experiments.
To achieve good performance during the simulation, the control frequency of inner loops is 400 Hz while the outer loops are at 10 Hz (see Section 2.2).
In the simulations, the catenary shape of the power line is expressed as:
wz=coshawxn−wl/2+wh,E21
where wz is the vertical position of the power line in local coordinates, wl=90 is the distance between two towers the wire is attached to, and taking aw=0.03, wh=8 give a sag of 1 m with towers height of 10 m.
Simulation results are shown in Figure 10. It can be seen from the same figure that the position error is negligible and converges quite fast.
Figure 10.
Power line tracking simulation result. (a) Position error, (b) vehicle position vs power line, (c) vehicle speed, (d) roll and pitch body angles.
4.3 Ground wire tracking experiment
In this section, the experimental results of actual ground line tracking flight are shown. The experimental setting is the same as the simulation one (see Figure 9). The diameter of the wire is 8 mm. The flights were performed autonomously, as explained in Section 3.3. The experimental results are shown in Figures 11 and 12.
Figure 11.
Ground wire tracking experiment. (a) Position error, (b) UAV path.
Figure 12.
GW tracking experiment in presence of strong wind. (a) Position error, (b) wind speed and direction, (c) control input, (d) UAV path.
The graphs in Figure 11a depict the position errors. The error in the vertical direction is less than ±0.2 m and but the control quality is good. Figure 11b shows the vehicle trajectory—the catenary shape of the wire is well tracked. The vehicle speed was 0.7 m/s.
The graphs in Figure 12 are taken in the presence of quite strong wind. It can be seen from the graph shown in Figure 12a that the position error in a vertical direction is small, but the error in the horizontal direction is about ±0.5 m. Figure 12b shows the wind speed and direction measured using an anemometer mounted on the vehicle body. The wind speed and direction are measured in 0.33 s interval, and graphs present 1 s average values. However, there were sudden changes in the wind speed up to 9 m/s. Figure 12c and d depict the control input and the catenary shape of vehicle trajectory. The vehicle speed in this experiment was 1.4 m/s.
Two images acquired during vehicle flight are depicted in Figure 13. Some minor defects can be observed there.
Figure 13.
Images of ground wire. (a) Defect caused by a lightning strike. (b) Two minor defects.
5. Conclusions
This work aims to develop a reliable autonomous power line tracking and inspection system based on a quadrotor helicopter. The model of the UAV was presented and evaluated in simulation and experiments performed in the real environment. Classical PID controllers were deployed, and their performances were demonstrated during ground wire line tracking. It can be concluded that the PID controller had a good performance, but in windy weather conditions, the position error increases to some extend. The presented system has almost Level 4 autonomy in the sense that it can perform flights beyond visual line of sight and without operator based navigation.
As a part of future work, we will implement a fuzzy PID controller to explore if further performance improvement can be achieved. This system will be implemented on regular inspections and maintenance of power facilities in an electric power company in Japan.
Acknowledgments
This research is performed in cooperation with Electric Power Development Co., LTD. from Tokyo, Japan. The authors would like to thank for their financial support of this project. We want to thank Mr. K. Tanaka, Mr. T. Sugiyama and Mr. Y. Oota from the same company for their help and support in performing most of the experiments.
\n',keywords:"power line tracking, UAV navigation, power line inspection, quadrotor helicopter, field robotics",chapterPDFUrl:"https://cdn.intechopen.com/pdfs/78679.pdf",chapterXML:"https://mts.intechopen.com/source/xml/78679.xml",downloadPdfUrl:"/chapter/pdf-download/78679",previewPdfUrl:"/chapter/pdf-preview/78679",totalDownloads:198,totalViews:0,totalCrossrefCites:0,totalDimensionsCites:0,totalAltmetricsMentions:0,impactScore:0,impactScorePercentile:43,impactScoreQuartile:2,hasAltmetrics:0,dateSubmitted:null,dateReviewed:"August 23rd 2021",datePrePublished:"September 20th 2021",datePublished:"January 26th 2022",dateFinished:"September 20th 2021",readingETA:"0",abstract:"This work presents some results about power transmission line tracking control and a full autonomous inspection using a quadrotor helicopter. The presented in this paper power line autonomous inspection allows detecting power line defects caused by thunderstorms, corrosion, insulator malfunctions, and same time monitoring of vegetation under the power line corridor. Traditional inspection is performed by helicopters equipped with high-resolution cameras or by direct visual examination carried out by highly skilled staff climbing over de-energized power lines. However, the visual inspection is time-expensive and costly. Moreover, due to regulatory constraints, the helicopters cannot cover narrow mountainous areas. Unmanned aerial vehicles (UAV) are an attractive alternative for power line inspection. In this work, a mathematical model for the quadrotor helicopter used in the autonomous inspection is presented. The model is successfully evaluated through simulations and flight experiments. Next, the construction of a quadrotor helicopter system and its application to power line autonomous inspection is introduced. Simulation and experimental results demonstrate the efficiency and applicability of that system. The results of this research are in the process of implementation for regular inspection of electrical transmission lines.",reviewType:"peer-reviewed",bibtexUrl:"/chapter/bibtex/78679",risUrl:"/chapter/ris/78679",book:{id:"10655",slug:"motion-planning"},signatures:"Kenta Takaya, Hiroshi Ohta, Keishi Shibayama and Valeri Kroumov",authors:[{id:"68141",title:"Prof.",name:"Valeri",middleName:null,surname:"Kroumov",fullName:"Valeri Kroumov",slug:"valeri-kroumov",email:"val@ee.ous.ac.jp",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:{name:"Okayama University of Science",institutionURL:null,country:{name:"Japan"}}},{id:"417213",title:"Mr.",name:"Kenta",middleName:null,surname:"Takaya",fullName:"Kenta Takaya",slug:"kenta-takaya",email:"kenta@kids.ee.ous.ac.jp",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:{name:"Okayama University of Science",institutionURL:null,country:{name:"Japan"}}},{id:"417214",title:"Dr.",name:"Hiroshi",middleName:null,surname:"Ohta",fullName:"Hiroshi Ohta",slug:"hiroshi-ohta",email:"ohta@ee.ous.ac.jp",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:{name:"Okayama University of Science",institutionURL:null,country:{name:"Japan"}}},{id:"417216",title:"Dr.",name:"Keishi",middleName:null,surname:"Shibayama",fullName:"Keishi Shibayama",slug:"keishi-shibayama",email:"keishi@scale-ag.jp",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null}],sections:[{id:"sec_1",title:"1. Introduction",level:"1"},{id:"sec_2",title:"2. Quadrotor helicopter dynamics and control",level:"1"},{id:"sec_2_2",title:"2.1 Quadrotor dynamics",level:"2"},{id:"sec_3_2",title:"2.2 Control scheme",level:"2"},{id:"sec_5",title:"3. Power line autonomous inspection system architecture",level:"1"},{id:"sec_5_2",title:"3.1 Hardware design",level:"2"},{id:"sec_6_2",title:"3.2 Software",level:"2"},{id:"sec_7_2",title:"3.3 Power line tracking",level:"2"},{id:"sec_9",title:"4. Simulation and experimental results",level:"1"},{id:"sec_9_2",title:"4.1 Step response simulation and experiments",level:"2"},{id:"sec_10_2",title:"4.2 Power line tracking simulation",level:"2"},{id:"sec_11_2",title:"4.3 Ground wire tracking experiment",level:"2"},{id:"sec_13",title:"5. 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Rada",authors:[{id:"114650",title:"Dr",name:"Eugen",middleName:null,surname:"Culea",fullName:"Eugen Culea",slug:"eugen-culea"},{id:"114653",title:"Dr.",name:"Simona",middleName:null,surname:"Rada",fullName:"Simona Rada",slug:"simona-rada"}]},{id:"36169",title:"Water in Rocks and Minerals - Species, Distributions, and Temperature Dependences",slug:"water-in-rocks-and-minerals-species-distributions-and-temperature-dependences",signatures:"Jun-ichi Fukuda",authors:[{id:"105384",title:"Dr.",name:"Jun-Ichi",middleName:null,surname:"Fukuda",fullName:"Jun-Ichi Fukuda",slug:"jun-ichi-fukuda"}]},{id:"36170",title:"Attenuated Total Reflection - Infrared Spectroscopy Applied to the Study of Mineral - Aqueous Electrolyte Solution Interfaces: A General Overview and a Case Study",slug:"attenuated-total-reflection-infrared-spectroscopy-applied-to-the-study-of-mineral-aqueous-el",signatures:"Grégory Lefèvre, Tajana Preočanin and Johannes Lützenkirchen",authors:[{id:"108416",title:"Dr.",name:"Johannes",middleName:null,surname:"Lützenkirchen",fullName:"Johannes Lützenkirchen",slug:"johannes-lutzenkirchen"},{id:"111675",title:"Dr.",name:"Gregory",middleName:null,surname:"Lefevre",fullName:"Gregory Lefevre",slug:"gregory-lefevre"},{id:"111676",title:"Prof.",name:"Tajana",middleName:null,surname:"Preocanin",fullName:"Tajana Preocanin",slug:"tajana-preocanin"}]},{id:"36171",title:"Research of Calcium Phosphates Using Fourier Transform Infrared Spectroscopy",slug:"research-of-calcium-phosphates-using-fourier-transformation-infrared-spectroscopy",signatures:"Liga Berzina-Cimdina and Natalija Borodajenko",authors:[{id:"110522",title:"Prof.",name:"Liga",middleName:null,surname:"Berzina-Cimdina",fullName:"Liga Berzina-Cimdina",slug:"liga-berzina-cimdina"},{id:"112181",title:"MSc.",name:"Natalija",middleName:null,surname:"Borodajenko",fullName:"Natalija Borodajenko",slug:"natalija-borodajenko"}]},{id:"36172",title:"FTIR Spectroscopy of Adsorbed Probe Molecules for Analyzing the Surface Properties of Supported Pt (Pd) Catalysts",slug:"ftir-spectroscopy-of-adsorbed-probe-molecules-for-analyzing-the-surface-properties-of-supported-pt-p",signatures:"Olga B. 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1. Introduction
Light is a major abiotic factor acts as energy source and signalling for plants growth and developments. Sun light is the prime source of energy on this planet and regulates number of essential functions in living organisms. Among them, primary producer as plants, blue green algae and photoautotrophs absorb these lights (especially 400-700 nm refereed as photosynthetically active radiation) and convert into energy source (starch, sucrose and other complex organic compound as food reserve) through the mechanism of photosynthesis [1]. Moreover, other living organisms like heterotrophs (primary consumer and secondary consumers) fulfil their energy requirements via feeding the primary producer food reserves. Therefore, light is an essential factor for all living organism to fulfil their energy requirements. Another important function of light is to act as regulator of signalling along with growth and development functions of plant. For example, photomorphogenesis (light regulated morphogenesis), phototropism (light mediated movements), circadian rhythm (light regulated biological rhythms) and many other crucial processes are under control of light [2]. Light characteristics such as intensity, duration, and wavelength affect the living organisms including plant in positive and negative way. Similarly, from millions of years plants are adaptive themselves to the diurnal changes of light–dark timings and many of the research concluded that change in light–dark duration affect plant growth mild to very drastic levels [3]. However, recent advancement in human development such as highway, buildings, LEDs lightening technology, product advertisements and industries progression lead to generation of excess light in the surrounding which causes anthropogenic accelerated light pollutions. Unlike natural ecosystems, where daily activities are scheduled by natural light–dark diurnal cycles [4], cities are heavily lit to enable performance of a wide array of activities after dark [5]. As artificial light at night (ALAN) becomes more reliable, efficient and affordable, living organisms become increasingly exposed to drastic and pervasive effects of “light pollution.”
According to Encyclopaedia Britannica, “light pollution” is “unwanted or excessive artificial light” during night hours. The introduction of ALAN into the environment majorly through electric light sources related to domestic purpose, industrial areas, transportation and street lights. The artificial night light altered the natural light cycle through its beneficial along with harmful effects on the plant ecosystem. Its beneficial impacts imply reduced the risk of night-road accident, the crime rate at night (approximately 30%), and increased working hours and scientific research areas such as speed breeding and tissue culture [6]. Therefore, there is a need to balance the positive and negative impacts of ALAN. Biology can be a science of timing/duration, for example all organisms experience the drastic results due to change in natural light cycle variations [6]. They are the utmost important physical factors for time. These include common daily activities (e.g. photosynthetic activity, stomatal movements, enzyme activity, flower opening, sleep movements, fragrance emission, dark recovery and repair). Indeed, the lunar cycle and the yearly/seasonal cycle dominate and regulate the lives of most organisms. Influences on biological life history have repeatedly been found to create events that occur later in life. Climatic changes can cause food and reproductive capacity to become mismatched, which in turn leads to organisms projecting highly developed phenology [7]. Likewise, plant-environment interaction is very important to decide the present and future growth of living organisms including plants. It has been documented that ALAN affects the micro-environment attributes such as light, soil biology, humidity, biotic community and their interactions surrounding the living organisms including plant [8, 9]. Moreover, in few recent studies it was showed that ALAN not only limited to light area but it can affect the living organism beyond this and can drastically affects the ecosystem services and biodiversity [10]. Consequently, pollination, net primary productivity, flowering, ecosystem services and nutrient recycling are the important eco-physiological functions, which are influenced by ALAN. The effect of ALAN in living organisms such as animals and humans are studied very well and several studies, and meta-analyses showed the effects on as behaviour (sleep, food, foraging, and flying), reproduction, vigilance and many other important activities [11, 12]. However, the effect of ALAN are very limited till date, only in last few years scientists are working on the ALAN and plant processes relationships and achieved some milestones. While considering the above facts, this chapter covers the present advances in ALAN research on plants specific to biorhythms and eco-physiological functions. Consequently, this analysis point out on some important strategies which are crucial for minimizing the extent of this pollution in environment.
2. Artificial light at night (ALAN) current status and anthropogenic sources of ALAN
Human development is continuous and complex process, also crucial for their existence for long term on this planet. This process culminates a number of novel pollutants (also known as anthropogenic pollutants) and creates a problem of other living organisms also environment sustainability. Although, this emerging pollution is global problem but the conditions might be severe when the pollution affects the endangered species in protected areas and natural hotspots [13]. Therefore, researchers tried to quantifying the ALAN worldwide by data generated from remote sensing technology, geographical information system, hyperspectral, visual infrared imaging radiometer, day/night band, and satellites [14, 15, 16]. In the year 2001, the first globe atlas of artificial night sky brightness based on US air force satellite data, which reported that the brightness of sky is increasing continuously and in world nearly two-third of world population living in an area where ALAN is higher than threshold limits (when the artificial night light brightness is greater than 10% of natural brightness). Also, many countries such as US had this value much higher and above 99% population facing this problem [17]. Consequently, the new world atlas on artificial night light brightness by using satellite data, day/night band, and Suomi national polar orbiting partnership satellite, which improve the resolution and accuracy reported that in new world 80% of world population facing the problem of excess night light brightness (brightness >14μcd/m2) [15]. Therefore, ALAN is spreading swiftly and considered as global problem and now every countries trying to study the trend of light brightness in their protected area using advanced technology. For example, India analyse the trend from 1993–2013 using defense meteorological satellite programme, which help in identifying the sensitive sites such as protected areas and setting the new light policies and priorities [18]. Although the ALAN varies in intensity, colour, timing, and wavelengths and also vary with the particular country and location. A list of ten highly polluted night light brightness cities of world and India are showed in Figure 1(a,b). In the represented figures, data on light brightness using light pollution map reveals that the situation of some cities in world such as Doha, Abu Dhabi, and Kuwait are very crucial as they have light brightness >160nW/cm2*Sr., which is 3–4 times higher than highly night light polluted brightness (50nW/cm2*Sr. considered as highly light polluted area).
Figure 1.
(a, b) Represent the list of top ten world highly night light brighten cities (mean value of 28.27 km2 area at 10 km elevation) of world, (highest value is near to 185 which is very high), and India during the year 2019-2020. Data procured from https://www.lightpollutionmap.info/.
The natural sky glow during night consists of comes from moon light, integrated starlight’s, zodiacal light and airglow. In the recent times due to anthropogenic activities excess light generated in the surrounding that causes disappearance of natural darkness, artificial glow in sky, and loss in visibility of the stars and Milky Way’s [19]. There are several anthropogenic factors that are responsible for pollution in night light such as decorative lightening during various festivals, lightening in buildings, malls and in homes, traffic light (consist of four wheeler, two wheeler light), road/highway light (to reduce accidents), advertisement light (to enhance marketing of different products), ship and aeroplane light, and street lightening [20]. These artificial lights vary in wavelength, timing (few minutes to whole night), colour (violet to red) and intensity (very low to very high). Also, the origin of this lightening varies such as LEDs light (light emitting diode), halogen light, tungsten bulb, and florescent light (tube lights). Moreover, it varies with the locations such as market area having light for 3 to 4 hours, home lights early evening hours and road light (whole night).
3. Plant biorhythms or circadian rhythms and their response under light and dark cycle
Biorhythms are known as adjustment mechanism in living systems that keep body homeostatis, adaptive processes and dynamic equilibrium. Biological rhythms are endogenous and closely linked with external environmental elements but regulated by endogenously such as genes. Phytochrome and cryptochrome pigment plays a key role in coordination and regulation of plant biorhythms [21, 22]. Phytocrome repons to red and far-red light, while crytochrome responds to ultra violet/blue light. Arabidopsis has five phytochrome PHYA to PHYE and two crytochrome CRY1 and CRY2 [21, 22]. Plant biorhthms are mostly classified as (a) cicadian rhythms; (around or approximately; dies meaning day), (b) circaseptan rhythms; (weekly), (c) circalunar rhythms; (monthly), (d) circannual rhythm; (annual) [21, 23, 24]. In different way, biorhythms classified on the basis of duration for example, (a) short duration; on the order of seconds or minutes for example water and ion exchange across the cell membranes, (b) long duration; varies from days to months for example complex sequence of events and the quantitative changes regulated at cell, tissue and organ level [25, 26, 27, 28]. Moreover other classification of biorthyms include (a) ecological rhythms; monthly, seasonal or diurnal (b) Physiological rhythms; based on various organs bioelectric activity [29, 30].
Among the all known rhythms, circadian thythms are very well known and documented by many reserchers. Circadian clocks are the biological oscillators that enable the organism to coordinate their physiology and behavior under periodic environmental fluctuations and also evolved in organisms in response to the daily rotation of the earth [23]. Circadian clock can influence diverse plant crucial processes like leaf movement, photosynthesis, stem extension, stomatal opening and hormonal regulations [23]. The circadian clock constitutes of three components: input, central oscillator and output pathways. Each component contains a number of genes i. e., PHYs (PHYTOCHROMEs), CRYs (CRYPTOCHROMEs) and PHOTs (PHOTOTROPINs) are the very well recognized light receptor genes of input pathways and transmit external light stimuli into the central oscillator [31]. Phytochrome interacting factor 3 (PIF3), ZEITLUPE (ZTL), PSUEDO-RESPONSE REGULATOR (PRR) have important role during light signalling and affects the circadian clock [32]. Free running period (FRP) is the period length of cercadian rhythms measured under constant conditions and varies among tissues, organisms and even cells of the same cell type [32]. In circadian of Arabidopsis thaliana oscillator consist of interlocking transcriptional feedback loops and control signicant process such as growth and metabolism. Circadian rhythms defined by three fundamental parameters: Periodicity; time to complete one cycle of 24 hours [33], Entrainability; circadian rhythms are self-sustaining and endogenously generated, therefore they maintain under constant environmental conditions like constant light or dark and temperature, Temperature compensation; the period remain relatively constant over a range of ambient temperature.
The circadian rhythm is closely associated to the light–dark cycle. Circadian rhythms remain consistent in response to no time cues but can be entrained by ambient conditions. But it’s been clear that different stimuli have varying effects on our circadian rhythms. Many environmental parameters provide stimulus to the clock, where the best characterized and most potent entraining stimulus is light in plants [34, 35]. Further, it is shows that shoot tip sends an unknown signal to the roots so root maintain circadian rhythm. While the lack of shoot apex signals loss of rhythmicity in the decapitated root, which can be overcome by direct exposure of root to LD cycles (light: dark) even as low intensities. It is clear that roots are entrained by light in preference to shoot apex derived signals [36]. In the context of photoperiodism, the circadian rhythm is combined with light signaling. The photoperiod sensor permits plants to respond to the annual cycle of day length, by the production of flowers, tubers and frost tolerant buds in appropriate seasons [37]. Accurate entrainment is important for photoperiodism, certainly general physiology shows that the crucial difference between light dominant plants (most of the flowering in long days) and dark dominant plants (most flowering in short days) is in the entrainment of their photoperiodic rhythm [38]. In light signaling pathways both phytochrome (phy) and cryptochrome (cry) regulate clock components to attain entrainment in plants [39]. The phytochrome responds to a red light and the cryptochrome absorbs in the UV-A/blue wavelength. Recognition of variations in day length confers plants seasonal flowering. This mechanism includes a time-keeping mechanism that integrates intimation of light environment to estimate the duration of day or night. Time-keeping activity is the outcome of the circadian clock. In Arabidopsis, an increase in flowering under long days (LD) happens through transcriptional induction of florigen gene FLOWERING LOCUS T (FT) specifically under LD conditions. The FT promoter binds with CONSTANS (CO) transcription factor which directly confer its LD-specific induction [40]. CONSTANS characterizes as a photoperiodic timer gene with its transcript level being managed by the circadian clock. CO proteins accumulate in response to exposure to light [41].
4. Impact of the artificial light at night time on circadian rhythms
As sessile plant receive light as signal and resource. Diurnal cycle of dark and light period is vital for regulating numerous processes in plants such as daily events of enzymes activity, gas exchange, photoperiodic movements, metabolism, stomatal movements, flowering opening, dark repair recovery and photosynthesis. The impact of artificial lighting on the body clock and its circadian rhythms is an important research topic. Night shifts introduction has changed the natural 24-hour cycle. There are multiple different categories of artificial lighting that are being utilized. It is various forms, from brief pulse to long lasting night glow, from narrow emission spectra to broad emission spectra, from low emission intensity to high intensity emission, and from local emission focus to glowing of sky. Effect of ALAN on some plant circadian process are disused thoroughly and represented in Figure 2.
Figure 2.
Represents the impact of artificial light at night on plant circadian and eco-physiological processes.
4.1 Enzyme activity or metabolism
It is very well documented that enzymes are essential for optimum growth and development of plant. Also, they help in regulating all the physiological, biochemical processes in plants. Important physiological and biochemical processes of plant include such as seed germination, photosynthesis, respiration, and translocation. In this regards an experiment conducted in rice using the different light intensity (from low to high) during night hours and observed that ALAN drastically reduce the germination capacity by reducing the activity of α-amylase enzyme [42]. Moreover, a recent study conducted perennial ryegrass using the different duration of light as light/dark hr. (24/0, 22/2, 20/4, 18/6, 16/8, and 14/10) and they had found that seed germination percentage (67 to 33%), soluble carbohydrates (27.48 to 9.16 mg/g fresh weight) and soluble protein (13.85 to 10.59 mg/g fresh weight) are lowest in 24/0 conditions as compared to 16/0 light/dark conditions, which showed the drastic effect on the future growth of plant [43]. In this array, a study conducted in yellow poplar using different light intensity from low 1 to high 50 μmol m−2 s−1 showed that in ALAN leading to reduction in starch turnover (74.7 to 11.4%) via affecting the starch synthesis activity and lower rate of respiration [44, 45]. Therefore, from these studies, it can be concluded that ALAN affect the metabolism of plant at early and late growth stages.
4.2 Stomatal movement and biomass
The stomata are very important for gas exchange and water transpiration in plants. It is also well documented that stomatal movement is circadian rhythm which is also influenced by the intensity and quality of light. In this regard, an experiment conducted using different photon flux density (1, 3, and 50 μmol m−2 s−1) and different light sources low pressure sodium lamp, high pressure sodium lamp and LEDs and they found shorter, narrower stomatal aperture, change in osmotic pressure and reduced stomatal size with increased stomatal density and the higher intensity more drastically affect the stomatal attributes in comparison with lower intensity of ALAN. Further, it is also found that the stomatal conductance is reduced under ALAN condition and affects the biomass accumulation and gas exchange [44, 45]. ALAN reduces the both above and below ground fresh and dry weight. Such as in the presence of 50 μmol m−2 s−1 in ryegrass during night time reduces the below ground fresh and dry weight by 48 and 46% respectively. Similarly, the reduction in above ground fresh and dry weight are 27 and 46% respectively. Therefore, it is expected that in future the result of ALAN might be more drastic and influence stomatal behaviours in plants.
4.3 Photosynthesis
Photosynthesis is the most crucial physiological process in autotrophs and essential for sustaining life on this planet. Earlier, it is documented that the sunlight is the prime source of energy for photosynthesis processes but in recent years many studies conducted using ALAN and found that it hampers the photosynthetic processes. In this aspect a recent experiment conducted using the street light having ALAN intensity near to 340-360lux and exhibited that plant under street light have lower photosynthetic quantum yield (Fv/Fm), non-photochemical quenching (NPQ) values, which ultimately affects the photosynthetic rate drastically [46]. Similarly, a study conducted in yellow poplar using different light intensity and quality during night hours reveals that total chlorophyll content reduced up to 35%, water use efficiency 23%, and photosynthetic rate 42 to 45% [45]. Another study reported in yellow poplar showed that the ALAN affect the ultrastructure of chloroplast by multiplying number of thylakoid membrane stack, reducing thylakoid stacking, and increasing number and size of plasoglobuli [44]. These modifications in chloroplast ultrastructure lead to early senescence, chloric and abnormal leaves. Consequently, ALAN in ryegrass influences the Chl a, chl b and total chlorophyll content, Fv/Fm ration, and electron transport chain. Further, they also ended up that the ALAN act as stressor and influence the photosynthetic efficiency of plants [43]. Therefore, it can be concluded that ALAN act as a stressor for photosynthetic phenomena and expected that in future it may be a global problem of road side trees.
4.4 Photoperiodic movements
The impact of relative length of flowering during day and night is refereed as photoperiodism. On the basis of day and night length plants are categorised into long day plant (required longer day length than critical period), short day plant (required shorter than crucial photoperiod) and day neutral plant (do not affect by day length). Therefore, flowering mechanism is very sensitive to critical day length. In the recent years it is found that ALAN severely affects the flowering mechanism in plants. For example, under ALAN and average spring temperature conditions at timing of budburst in deciduous tree species recorded and observed the budburst occurrence about 7.5 days earlier as compared to the normal UK conditions [47]. A long term experiment conducted to observe the impact of ALAN on wild species in natural and semi-natural grassland and authors found that the lightening affects the trajectory of vegetation cover, leading to change in plant biomass and the composition of dominant wild species. Further, they also suggested that the ALAN significantly alters the flowering phenology by shortening or lengthening of flowering period varies from 4 day earlier to 12 day late compared to control conditions [48]. Nevertheless, authors observed the non-significant relationship of ALAN with vegetation composition and flower density in grassland vegetation species. Further, they observed early flowering (about 4 days) in Agrostis tenuis and delayed flowering (about 7 days) in Anthoxanthum odoratum [49]. Thus, flowering behaviour of the plant species varies with ALAN (timing, duration, intensity, and spectrum etc.). Similarly, a study conducted on foredune vegetation such as Traganum moquinii receiving various light intensities during the year and author suggested that vegetation which face direct light or close to light source affected more and their flower and seed production is reduced drastically compared to species which located far from light source [50]. Also the flowering period can vary (reduced or increased) under ALAN, depend upon the type of plant species with their genetic constituents. For example, an experiment conducted using 1000-4000 lx light using LEDs and found that trees flowering are more susceptible than shrub species and plant species are more susceptible than evergreen species [51]. Therefore, it might be possible that in future the photoperiodism phenomenon affected more and can be responsible for evolutionary changes. The responses of plant circadian and ecological processes are represented in Figure 2.
5. Impact of ALAN on eco-physiological processes
As earlier mentioned ALAN is a global problem and it act as a stressor for living organisms including plant. Also, some recent studies exhibited that the impact of ALAN can be amplified with unfavourable conditions as pollution. Moreover, the living organisms or plants connected with environmental phenomenon and adaptive themselves. Many plant processes are associated to environment such as transpiration which depends upon the atmosphere humidity. Some of eco-physiological processes influenced by ALAN condition are followed and represented in Figure 2.
5.1 Plant growth and development
It is very well documented that the growth and development of plant is highly influenced by the environmental conditions. Also, a positive plant-environment interaction is necessary to grow plant under different environmental circumstances. The night hour lightening has great impact on the plant phenology, physiology, growth and development, reproduction and behaviours [52]. The light pollution is an emerging global phenomenon and accelerated by rapid urbanization, which affects both plant and animal fitness in both developed and developing countries, however the impact are very serious in urban areas. Contrary, it is observed that delayed autumn phenophases in the crown part of two tree species (Acer pseudoplatanus L. and Rhus typhina L.) positioned next to light source by 13 to 22 days and also deferred duration by 6–9 days. They also observed delayed leaf colouring duration by 6 to 9 days and leaf fall by 6 to 7 days due to ALAN [53]. A recent study conducted using ALAN in perennial wildflower regarding to observe the effect on growth and developments and they concluded that ALAN modulates the growth by interaction with abiotic factors such as soil moisture and affect plant density [8]. Likewise, recent study on the ecophysiological responses of ALAN in plants concluded that this had potential to alter the number of aspects such as germination, photosynthesis, biomass and yield [54]. In these consequences a recent study conducted using the different light intensities during night in rice and authors found out that the harmful impacts of light during night increased with light intensities and drastically reduces the seed germination (−14%), seedling vigour (16.83 to 12.51), root length (8.63 to 7.03) and early growth attributes such as seedling length (17.72 to 13.72 cm), mean time of germination (1.21 to 1.28), coefficient velocity of germination (82.61 to 78.07), germination index (526 to 465), germination rate index (87.83 to 78.50%/day) and mean germination rate (0.83 to 0.78) under artificial light conditions as compared to control, which directly associated the future growth of plant [42]. Moreover, in ryegrass reported that different intensity of light affects the leaf length (20.82 to 16.19 cm), leaf weight (1.02 to 0.58 g/10plants) and physiological parameters, which ultimately affects the growth in negative ways [43]. Therefore, it is expected that ALAN significantly hampers the growth and development of plant.
5.2 Pollination
Globally, pollinators are indispensable source of pollination in both agriculturally important crops and wild plants [55]. Anthropogenic activities such as intensive agriculture, use of extensive pesticides, habitat change, invasive alien species and climate change has substantially reduced population of pollinators [56]. Moreover, ALAN has emerged a new threat to plant reproductive success by disturbing plant-pollinator ecosystem balance. For example, authors witnessed the reduction of nocturnal pollinators visit by 62% in ALAN areas compared to the dark areas and yield was reduced by 13% [57]. They also observed visit of diurnal pollinators at night with nocturnal pollinators under ALAN. The pollinator-population dynamics and plant-pollinator communities are being adversely affected by artificial night lightening. Furthermore, ecological functionality and stability has been challenged by artificial night lightening throughout the world. Also the pollution effect of ALAN by nocturnal moths (Lepidoptera) and concluded that pollination is an ecosystem driven process that can be disturbed by increase of light pollution [58]. Similarly, recent study observed the negative relationship between direct ALAN and reproductive out in Epilobium angustifolium, plant species. This result can be due to disturb of pollination services in plants at nigh time by direct light illumination and cannot be compensated by day time pollinators [59]. Antagonistically, it is reported that there is no direct effect of light pollution on the reproductive output of Silene latifolia and possible only if diurnal pollinators compensate the decrease in pollination at night and another reason can be development of mechanism in pollinators which can manage the adverse effect of light pollution [59]. Thus, effect and extent of ALAN varies with plant species, and the behaviour of pollinators. Further, it can affect plant and animal biodiversity, species interaction particularly plant and pollinators, ecosystem balance and functioning.
5.3 ALAN as stressor
As sessile in nature plant faces a number of stressor throughout their life cycle such as abiotic stress (drought, heat, flood, cold, salinity, elevated CO2, and heavy metals), pollutions (air pollution, soil pollution), biotic stresses (insect, and pathogen), and most of times these stress are in combined from and cause for detrimental loss in their optimum growth and developments. All of these are act as stressor for plant and affect plant by changing the physiological, biochemical and molecular processes [60]. Likewise, this light also an important environmental factor and low and high light both act as stressor [42, 61]. Recent studies shows that ALAN also act as stressor and found out that it increases the lipid peroxidation, and reduces total antioxidant capacity in autotrophic red sea corals [62]. Further, an experiment in perennial ryegrass showed that ALAN increases the malondialdehyde (MDA) content and reduce leaf heat stability [43]. Similarly, it is observed that yellow poplar plant accumulate hydrogen peroxide, superoxide radicles and reduced abscisic content under ALAN conditions [44, 45]. Therefore, from these studies it may be concluded that ALAN act as a stressor and responsible for oxidative stress.
5.4 Ecosystem services under ALAN
Abiotic and biotic component of ecosystem coordinate to each other which provide important ecosystem services to humans. Also, the stability of ecosystems is key for sustaining of life on this planet. However, in the recent past due to uncontrolled anthropogenic activities ecosystem and biodiversity services of ecosystems are losing continuously. Among the anthropogenic activities, ALAN is one of the swiftly expanding activity, which is now become a global problem for ecosystem and biodiversity services [10, 63]. It is suggested that ALAN affect the organisms flux across the ecosystems and key driver of ecosystem community structure and can modify the ecosystem functioning beyond the affected area [64]. Moreover, the effects of ALAN are not limited to plants but also it affects the aquatic, forest, desert, terrestrial, mountain and agriculture ecosystem from lower to higher levels [10, 59]. Further it has been found the ALAN had drastic impact of ecosystem services such as foraging, vision, reproduction, signalling and behaviour. Therefore, it can be concluded that ALAN had serious impact on ecosystem services of stable ecosystems.
6. Minimizing strategy of ALAN
6.1 Street light pollution
Street lights should be replaced with energy-efficient LEDs and proper shielding of light in streets and by managing their angels. Street lights should be installed where needed Indian standards [65] has classified the roads according to the traffic density. By considering the road category according to traffic density engineers can design the street light plan and provide the installation specifications. To a report from [66], the Bruhat Bengaluru Mahanagara Palike (BBMP) projected a plan to replace the existing 4.8 lakh city street lights with high energy-efficient LED lights. A number studies conducted to showing their impact on plants ecosystems and hot spots and most of cases it affect in negative way. Although, some of researcher are concerned and documented about the impact of ALAN but there is no progress in changing the street lights. However, in recent time some countries follow the new light policies, where they replaced the old lights with more efficient lights and change the angle and height of light source to reduce the tree passes.
6.2 Buildings lights
This can be minimize using smart building architecture to decrease the use of excessive outdoor and indoor lights. The utilisation of LEDs, compact fluorescents (CFS) and warm coloured bulbs should be used to minimise energy use and by this way somehow we can protect our environment. The dimmers, motion-sensors and timers contribute a lot to energy saving. Turning-off the unnecessary indoor along with outdoor lights in houses and offices. Avoid Blue light during night time. International Dark Sky-Association (IDA) recommends use only warm lights for outdoor that includes low-pressure sodium (LPS), high-pressured Sodium (HPS) and low-colour LEDs. By using warm or filtered LEDs (CCT < 3,000 K; S/P ratio < 1.2) can reduce the blue light emission [67].
6.3 Government policies for ALAN
Artificial light pollution is now emerging pollution and governments has also considered it and have provided certain guidelines to decrease the energy wastage, damage to agro-ecological and wildlife ecosystem. During the 13th meeting of the Conference of the Parties, Gandhinagar, India Agenda No. 26.4 “the guidelines for light pollution for wildlife including marine turtle, seabirds and migratory shorebirds” under the Convention on the migratory species (prepared by the Government of Australia) [68]. By seeing the threat of sky glow and emerging challenges of increasing artificial light pollution to the marine species government has taken a proactive approach to develop artificial light in night pollution guidelines. These kinds of initiatives need to be taken by every country to combat artificial night light pollution. Artificial light at night became an unavoidable technology from the societies however this indispensable tool has harmful side effect in term of light pollution [69]. One can understand that artificial light at night is necessary to highlight the scenic beauties of the cities and to provide safety on roads however where artificial light at night is easily available at very low cost there it is over utilized which leads to discomfort in society with a view to disturbing the natural habitats, underline the beauty of skyline etc. Therefore now we can understand that ALAN has two phases of its representation. The detrimental effect can be seen through alteration in the sky glow which is an important constituent of biosphere [70]. According to one study, around one fifth of the global population affected by artificial sky brightness [17]. Challenge that we have is how we can use the ALAN in such a way that maximize the social benefits and reduce the impact of its pollution.
In this regards several articles are available at public domain [71, 72, 73, 74, 75, 76, 77, 78, 79]. They have summarized the solution like protecting species rich areas in their natural habitat, policy making on threshold and upper limit of light emission, environmental specific custom based light brightness which is adapted to vicinity of that area, time control of light emission, diurnal adapted colour spectrum and reducing the trespass of lightening. Apart from this, it is suggested that the five ways to minimize the harmful effect of ALAN viz. improving light fixtures to direct the light where it needed, switch the light off whenever it is not needed, dim the light and choose the appropriate Illuminants, colour spectra and filters, shade the light to protect the neighbor and learn from nature to maintain its sustainability [69]. Further, suggested to use the decreased height of light poles and increased spacing between light poles to reduce the pollution from ALAN [80]. It is also strongly recommended that environmental impact need to be considered in addition to energy consumption [81]. Moreover, considering the nature and landscape protection, protection of breeding sites and resting places of highly sensitive biological organism, assessing or measurement technology of ALAN pollution must improve to reduce the impact [82]. In addition to above explained policies author suggest that existing lighting plans must be evaluated and can be improved, reducing the decorative lightening, using of covered bulbs that face downwards, use of automatic system to turn off street light at certain times, outdoor lights with glare should be replaced with low glare, use of IDA approved light fixtures and use of motion sensors on important outdoor lights to reduce the impact of pollution caused by ALAN. Although, there are no specific light policy for reducing impact of street light on plant and living organisms but it may expected that in near future countries will adopt some new light policies. However, some of points can be considered under future light policies to reduce the impact of ALAN on plants, which are followed.
Reduce the height of light source to reduce tress passes
Change the angle and position of light source
Light source could be away from trees
Growing light insensitive tress and crops o road side areas such as day neutral species
Avoid short day plants near to highways
Promote self-pollinated species as compared to cross pollinated
Avoid cross-pollinated species especially which nocturnal pollinated
This approach can be milestone to reduce the impact of ALAN on plants.
7. Conclusion
Human population is continuously expanding and degradation of natural resources is also increasing with human development activities. ALAN has important role during the human development process as it increases the working hours, work efficiency, reduce crime and accidents but due to excess use and accumulation in environment cause a problem of artificial night light pollution. ALAN pollution is anthropogenic and increasing swiftly and has global impact. In the presented chapter we tried to explore the impact of ALAN on plant biological rhythms and ecophysiological processes. Therefore, this study comprises of the recent status of ALAN in world and their sources. In this we concluded that many countries are facing the problem of ALAN and continue expanding their area. Further, we discussed about the plant biorhythms and their regulation by diurnal cycles and concluded that the plant biorhythms are highly sensitive too change in light/dark periods. Thereafter, we provide the some details regarding the plant circadian rhythm, which are affected by ALAN and concluded that ALAN had negatively associated with them. Later on, we detail the some ecophysiological functions under ALAN and concluded that ALAN had drastic effects on plant processes and in future it can be a global problem. In the last we discussed the some strategies and approaches to minimize the effect of ALAN. Therefore, in this chapter we tried to comprise all the recent information, which help scientist to explore more about in this area of research.
\n',keywords:"artificial night light pollution, minimizing strategies, photosynthesis, pollination, plant growth and development, plant movements",chapterPDFUrl:"https://cdn.intechopen.com/pdfs/75498.pdf",chapterXML:"https://mts.intechopen.com/source/xml/75498.xml",downloadPdfUrl:"/chapter/pdf-download/75498",previewPdfUrl:"/chapter/pdf-preview/75498",totalDownloads:268,totalViews:0,totalCrossrefCites:0,dateSubmitted:"January 9th 2021",dateReviewed:"February 5th 2021",datePrePublished:"March 2nd 2021",datePublished:"March 30th 2022",dateFinished:"March 2nd 2021",readingETA:"0",abstract:"Light is crucial environmental factor for primary resource and signalling in plants and provide optimum fitness under fluctuating environments from millions of year. However, due to urbanization, and human development activities lot of excess light generated in environment during night time and responsible for anthropogenic generated pollution (ALAN; artificial night light pollution). This pollution has cause for serious problem in plants as it affects their processes and functions which are under the control of light or diurnal cycle. Plant biorhythms mostly diurnal rhythms such as stomatal movements, photosynthetic activity, and many more metabolic processes are under the control of period of light and dark, which are crucially affected by artificial light at night. Similarly, the crucial plant processes such as pollination, flowering, and yield determining processes are controlled by the diurnal cycle and ALAN affects these processes and ultimately hampers the plant fitness and development. To keep in mind the effect of artificial light at night on plant biorhythm and eco-physiological processes, this chapter will focus on the status of global artificial night light pollution and the responsible factors. Further, we will explore the details mechanisms of plant biorhythm and eco-physiological processes under artificial light at night and how this mechanism can be a global threat. Then at the end we will focus on the ANLP reducing strategies such as new light policy, advanced lightening technology such as remote sensing and lightening utilisation optimisation.",reviewType:"peer-reviewed",bibtexUrl:"/chapter/bibtex/75498",risUrl:"/chapter/ris/75498",signatures:"Rekha Sodani, Udit Nandan Mishra, Subhash Chand, Indu, Hirdayesh Anuragi, Kailash Chandra, Jyoti Chauhan, Bandana Bose, Vivek Kumar, Gopal Shankar Singh, Devidutta Lenka and Rajesh Kumar Singhal",book:{id:"9653",type:"book",title:"Light Pollution, Urbanization and Ecology",subtitle:null,fullTitle:"Light Pollution, Urbanization and Ecology",slug:"light-pollution-urbanization-and-ecology",publishedDate:"March 30th 2022",bookSignature:"Levente Hufnagel",coverURL:"https://cdn.intechopen.com/books/images_new/9653.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",isbn:"978-1-83880-973-7",printIsbn:"978-1-83880-972-0",pdfIsbn:"978-1-83880-974-4",isAvailableForWebshopOrdering:!0,editors:[{id:"10864",title:"Dr.",name:"Levente",middleName:null,surname:"Hufnagel",slug:"levente-hufnagel",fullName:"Levente Hufnagel"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}},authors:[{id:"249796",title:"Dr.",name:"Kailash",middleName:null,surname:"Chandra",fullName:"Kailash Chandra",slug:"kailash-chandra",email:"kailash5026@gmail.com",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/249796/images/14922_n.jpg",institution:{name:"Sri Karan Narendra Agriculture University, Jobner",institutionURL:null,country:{name:"India"}}},{id:"320400",title:"Dr.",name:"Rajesh",middleName:null,surname:"Singhal",fullName:"Rajesh Singhal",slug:"rajesh-singhal",email:"rajasinghal151@gmail.com",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"326742",title:"Dr.",name:"Subhash",middleName:null,surname:"Chand",fullName:"Subhash Chand",slug:"subhash-chand",email:"subhashchand5415@gmail.com",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"332315",title:"Dr.",name:"Indu",middleName:null,surname:null,fullName:"Indu null",slug:"indu",email:"indubachchan24@gmail.com",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"337943",title:"Dr.",name:"Rekha",middleName:null,surname:"Sodani",fullName:"Rekha Sodani",slug:"rekha-sodani",email:"rekha.sodani093@gmail.com",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"338585",title:"Dr.",name:"Udit Nandan",middleName:null,surname:"Mishra",fullName:"Udit Nandan Mishra",slug:"udit-nandan-mishra",email:"muditnandan@gmail.com",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"338588",title:"Ms.",name:"Devidutta",middleName:null,surname:"Lenka",fullName:"Devidutta Lenka",slug:"devidutta-lenka",email:"devidutta.lenka16@gmail.com",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:{name:"Assam Agricultural University",institutionURL:null,country:{name:"India"}}},{id:"345755",title:"Mr.",name:"Hirdayesh",middleName:null,surname:"Anuragi",fullName:"Hirdayesh Anuragi",slug:"hirdayesh-anuragi",email:"heartyanuragi@gmail.com",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"345756",title:"Dr.",name:"Jyoti",middleName:null,surname:"Chauhan",fullName:"Jyoti Chauhan",slug:"jyoti-chauhan",email:"jc6173000@gmail.com",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"345757",title:"Prof.",name:"Bandana",middleName:null,surname:"Bose",fullName:"Bandana Bose",slug:"bandana-bose",email:"bbosebhu@gmail.com",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:{name:"Banaras Hindu University",institutionURL:null,country:{name:"India"}}},{id:"345758",title:"Mr.",name:"Vivek",middleName:null,surname:"Kumar",fullName:"Vivek Kumar",slug:"vivek-kumar",email:"vkvivekmdl@gmail.com",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:{name:"Banaras Hindu University",institutionURL:null,country:{name:"India"}}},{id:"345759",title:"Prof.",name:"Gopal Shankar",middleName:null,surname:"Singh",fullName:"Gopal Shankar Singh",slug:"gopal-shankar-singh",email:"gopalsingh.bhu@gmail.com",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:{name:"Banaras Hindu University",institutionURL:null,country:{name:"India"}}}],sections:[{id:"sec_1",title:"1. Introduction",level:"1"},{id:"sec_2",title:"2. Artificial light at night (ALAN) current status and anthropogenic sources of ALAN",level:"1"},{id:"sec_3",title:"3. Plant biorhythms or circadian rhythms and their response under light and dark cycle",level:"1"},{id:"sec_4",title:"4. Impact of the artificial light at night time on circadian rhythms",level:"1"},{id:"sec_4_2",title:"4.1 Enzyme activity or metabolism",level:"2"},{id:"sec_5_2",title:"4.2 Stomatal movement and biomass",level:"2"},{id:"sec_6_2",title:"4.3 Photosynthesis",level:"2"},{id:"sec_7_2",title:"4.4 Photoperiodic movements",level:"2"},{id:"sec_9",title:"5. Impact of ALAN on eco-physiological processes",level:"1"},{id:"sec_9_2",title:"5.1 Plant growth and development",level:"2"},{id:"sec_10_2",title:"5.2 Pollination",level:"2"},{id:"sec_11_2",title:"5.3 ALAN as stressor",level:"2"},{id:"sec_12_2",title:"5.4 Ecosystem services under ALAN",level:"2"},{id:"sec_14",title:"6. Minimizing strategy of ALAN",level:"1"},{id:"sec_14_2",title:"6.1 Street light pollution",level:"2"},{id:"sec_15_2",title:"6.2 Buildings lights",level:"2"},{id:"sec_16_2",title:"6.3 Government policies for ALAN",level:"2"},{id:"sec_18",title:"7. Conclusion",level:"1"}],chapterReferences:[{id:"B1",body:'Sharkey TD. Emerging research in plant photosynthesis. Emerging topics in life sciences. 2020; 4(2): 137-150'},{id:"B2",body:'Kami C, Lorrain S, Hornitschek P, Fankhauser C. Light-regulated plant growth and development. In Current topics in developmental biology. CRC Academic Press. 2010: 29-66'},{id:"B3",body:'Nozue K, Maloof JN. Diurnal regulation of plant growth. Plant Cell and Environment. 2006; 29(3): 396-408'},{id:"B4",body:'Svechkina A, Portnov BA, Trop T. The impact of artificial light at night on human and ecosystem health: a systematic literature review. Landscape Ecology. 2020: 1-18'},{id:"B5",body:'Haim A, Portnov BA. 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Working with inadequate tools: Legislative shortcomings in protection against ecological effects of artificial light at night. Sustainability 2020; 12(6), 2551'}],footnotes:[],contributors:[{corresp:null,contributorFullName:"Rekha Sodani",address:null,affiliation:'
College of Agriculture, Nagur, Agriculture University, India
ICAR-Indian Grassland and Fodder Research Institute, India
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This is followed by a brief discussion of the signal processing required to obtain energy consumption data from sensing. We then present two energy measurement systems that are based on sensing techniques. Both can be used to directly measure the energy consumed by software running on embedded systems without the need to modify the hardware. As an alternative, regression-based techniques can be used to infer energy consumption based on monitoring events during program execution using counters monitors offered by the hardware. We introduce the foundations of regression analysis and illustrate how an energy model for an ARM processor can be built using linear regression. 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Paul is the director of the JWNC in the School of Engineering at the University of Glasgow, and he was awarded an EPSRC Quantum Technology Fellowship in 2015. He won the Institute of Physics President’s Medal in 2014 for ‘his outstanding contribution to the translation of university physics research into advanced technology’. He has been a PI on £22.8M of research grants and a co-I on £56.2M of projects inside collaborative projects with a total value of £133.7M from industry, EPSRC, EC, DARPA and others. He has 3 patents and over 223 publications and gave over 20 invited talks at international meetings in the last 12 months. He works on nanofabrication, quantum technology, photonics, energy harvesting and MEMS gravimeters. He has worked with over 70 companies in a wide range of research and development projects.",institutionString:null,institution:{name:"University of Glasgow",institutionURL:null,country:{name:"United Kingdom"}}},{id:"185597",title:"Mr.",name:"Martin",surname:"Wlotzka",slug:"martin-wlotzka",fullName:"Martin Wlotzka",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Heidelberg University",institutionURL:null,country:{name:"Germany"}}},{id:"185803",title:"Prof.",name:"Kerstin",surname:"Eder",slug:"kerstin-eder",fullName:"Kerstin Eder",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/185803/images/5332_n.jpg",biography:"Kerstin Eder is Professor of Computer Science at the University of Bristol, UK. She set up the Energy Aware COmputing (EACO) initiative (http://www.cs.bris.ac.uk/Research/eaco/) and leads the Verification and Validation for Safety in Robots research theme at the Bristol Robotics Laboratory (http://www.brl.ac.uk/vv). Her research is focused on specification, verification and analysis techniques which allow engineers to design a system and to verify/explore its behaviour in terms of functional correctness, performance and energy efficiency. Kerstin has gained extensive experience of verifying complex microelectronic designs while working with leading semiconductor design and Electronic Design Automation companies. In her research she seeks novel combinations of techniques to achieve solutions that make a difference in practice. Her most recent work includes intelligent, agent-based testing of code for robots that directly interact with humans, using assertion checks and theorem proving to verify control system designs, energy modelling of software and static analysis to predict energy consumption of programs. She is particularly interested in safety assurance for learning machines. \n\nKerstin was a Principal Investigator of the EC FP7 FET MINECC (Minimizing Energy Consumption of Computing to the Limit) collaborative research project ENTRA (Whole Systems Energy Transparency), which developed techniques to promote energy efficiency to a first class software design goal utilizing advanced energy modelling and static analysis techniques. At the Bristol Robotics Laboratory she is the Principal Investigator of two EPSRC projects: RIVERAS (Robust Integrated Verification of Autonomous Systems) and ROBOSAFE (Trustworthy Robotic Assistants). Kerstin has co-authored over 70 internationally refereed publications and was awarded a Royal Academy of Engineering \\Excellence in Engineering\\ prize. She holds a PhD in Computational Logic, an MSc in Artificial Intelligence and an MEng in Informatics.",institutionString:null,institution:{name:"University of Bristol",institutionURL:null,country:{name:"United Kingdom"}}},{id:"186363",title:"Dr.",name:"Azam",surname:"Seyedi",slug:"azam-seyedi",fullName:"Azam Seyedi",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Barcelona Supercomputing Center",institutionURL:null,country:{name:"Spain"}}},{id:"187818",title:"Prof.",name:"John P.",surname:"Gallagher",slug:"john-p.-gallagher",fullName:"John P. Gallagher",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/187818/images/5269_n.jpg",biography:"John P. Gallagher received his BA (Mathematics with Philosophy) and PhD (Computer Science) degrees from Trinity College, Dublin, in 1976 and 1983, respectively. He held post-doc positions in Trinity College, Dublin, Weizmann Institute of Science, Israel, and Katholieke Universiteit Leuven, Belgium, and performed research and development in a software company in Hamburg, Germany. Between 1990 and 2002, he was at the University of Bristol, UK. Since 2002, he has been a professor at the University of Roskilde, Denmark, in the research group Programming, Logic and Intelligent Systems and holds a dual appointment as research professor at the IMDEA Software Institute since February 2007. He is an area editor for the journal Theory and Practice of Logic Programming. His research interests focus on programme transformation, software analysis, semantics-based emulation of languages and systems and verification using abstraction, and he has participated in several national and European research projects on these topics.",institutionString:null,institution:{name:"Roskilde University",institutionURL:null,country:{name:"Denmark"}}},{id:"188048",title:"Prof.",name:"Vincent",surname:"Heuveline",slug:"vincent-heuveline",fullName:"Vincent Heuveline",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"188049",title:"Dr.",name:"Manuel F.",surname:"Dolz",slug:"manuel-f.-dolz",fullName:"Manuel F. Dolz",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Carlos III University of Madrid",institutionURL:null,country:{name:"Spain"}}},{id:"189880",title:"Dr.",name:"Dirk",surname:"Pesch",slug:"dirk-pesch",fullName:"Dirk Pesch",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Cork Institute of Technology",institutionURL:null,country:{name:"Ireland"}}},{id:"191964",title:"Dr.",name:"David",surname:"Boyle",slug:"david-boyle",fullName:"David Boyle",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"209333",title:"Dr.",name:"Steve",surname:"Kerrison",slug:"steve-kerrison",fullName:"Steve Kerrison",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/209333/images/5494_n.jpg",biography:"Steve Kerrison has worked in various areas relating to embedded systems and computer architecture, including verification, simulation, energy modeling and network-on-chip, as well as industrial applications for the Internet of Things. He was a researcher on the EC FP7 ENTRA (Whole Systems Energy Transparency - http://entraproject.eu/) project,\nstrengthening the links of understanding between software and its affect on device energy consumption. Steve has researched predictable Network on Chip implementations as part of the ARTEMIS Joint Undertaking project EMC2 (http://www.artemis-emc2.eu/), a project composed of over one hundred partners, all with an interest in advancing multi-core technology into embedded mixed criticality systems and associated industrial sectors. He has also been involved in the EC FET coordination action ICT-Energy (http://www.ict-energy.eu/), furthering the discussion of techniques for ICT energy reduction between experts across disciplines, as well as seeking to engage the public and new researchers.",institutionString:null,institution:null}]},generic:{page:{slug:"unsubscribe-successful",title:"Unsubscribe Successful",intro:"
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",metaTitle:"Unsubscribe Successful",metaDescription:"You have been successfully unsubscribed.",metaKeywords:null,canonicalURL:"/page/unsubscribe-successful",contentRaw:'[{"type":"htmlEditorComponent","content":""}]'},components:[{type:"htmlEditorComponent",content:""}]},successStories:{items:[]},authorsAndEditors:{filterParams:{},profiles:[{id:"396",title:"Dr.",name:"Vedran",middleName:null,surname:"Kordic",slug:"vedran-kordic",fullName:"Vedran Kordic",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/396/images/7281_n.png",biography:"After obtaining his Master's degree in Mechanical Engineering he continued his education at the Vienna University of Technology where he obtained his PhD degree in 2004. He worked as a researcher at the Automation and Control Institute, Faculty of Electrical Engineering, Vienna University of Technology until 2008. His studies in robotics lead him not only to a PhD degree but also inspired him to co-found and build the International Journal of Advanced Robotic Systems - world's first Open Access journal in the field of robotics.",institutionString:null,institution:{name:"TU Wien",country:{name:"Austria"}}},{id:"441",title:"Ph.D.",name:"Jaekyu",middleName:null,surname:"Park",slug:"jaekyu-park",fullName:"Jaekyu Park",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/441/images/1881_n.jpg",biography:null,institutionString:null,institution:{name:"LG Corporation (South Korea)",country:{name:"Korea, South"}}},{id:"465",title:"Dr",name:"Christian",middleName:null,surname:"Martens",slug:"christian-martens",fullName:"Christian Martens",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"479",title:"Dr.",name:"Valentina",middleName:null,surname:"Colla",slug:"valentina-colla",fullName:"Valentina Colla",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/479/images/358_n.jpg",biography:null,institutionString:null,institution:{name:"Sant'Anna School of Advanced Studies",country:{name:"Italy"}}},{id:"494",title:"PhD",name:"Loris",middleName:null,surname:"Nanni",slug:"loris-nanni",fullName:"Loris Nanni",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/494/images/system/494.jpg",biography:"Loris Nanni received his Master Degree cum laude on June-2002 from the University of Bologna, and the April 26th 2006 he received his Ph.D. in Computer Engineering at DEIS, University of Bologna. On September, 29th 2006 he has won a post PhD fellowship from the university of Bologna (from October 2006 to October 2008), at the competitive examination he was ranked first in the industrial engineering area. He extensively served as referee for several international journals. He is author/coauthor of more than 100 research papers. He has been involved in some projects supported by MURST and European Community. 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Delac received his B.Sc.E.E. degree in 2003 and is currentlypursuing a Ph.D. degree at the University of Zagreb, Faculty of Electrical Engineering andComputing. His current research interests are digital image analysis, pattern recognition andbiometrics.",institutionString:null,institution:{name:"University of Zagreb",country:{name:"Croatia"}}},{id:"557",title:"Dr.",name:"Andon",middleName:"Venelinov",surname:"Topalov",slug:"andon-topalov",fullName:"Andon Topalov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/557/images/1927_n.jpg",biography:"Dr. Andon V. Topalov received the MSc degree in Control Engineering from the Faculty of Information Systems, Technologies, and Automation at Moscow State University of Civil Engineering (MGGU) in 1979. He then received his PhD degree in Control Engineering from the Department of Automation and Remote Control at Moscow State Mining University (MGSU), Moscow, in 1984. From 1985 to 1986, he was a Research Fellow in the Research Institute for Electronic Equipment, ZZU AD, Plovdiv, Bulgaria. In 1986, he joined the Department of Control Systems, Technical University of Sofia at the Plovdiv campus, where he is presently a Full Professor. He has held long-term visiting Professor/Scholar positions at various institutions in South Korea, Turkey, Mexico, Greece, Belgium, UK, and Germany. And he has coauthored one book and authored or coauthored more than 80 research papers in conference proceedings and journals. His current research interests are in the fields of intelligent control and robotics.",institutionString:null,institution:{name:"Technical University of Sofia",country:{name:"Bulgaria"}}},{id:"585",title:"Prof.",name:"Munir",middleName:null,surname:"Merdan",slug:"munir-merdan",fullName:"Munir Merdan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/585/images/system/585.jpg",biography:"Munir Merdan received the M.Sc. degree in mechanical engineering from the Technical University of Sarajevo, Bosnia and Herzegovina, in 2001, and the Ph.D. degree in electrical engineering from the Vienna University of Technology, Vienna, Austria, in 2009.Since 2005, he has been at the Automation and Control Institute, Vienna University of Technology, where he is currently a Senior Researcher. His research interests include the application of agent technology for achieving agile control in the manufacturing environment.",institutionString:null,institution:null},{id:"605",title:"Prof",name:"Dil",middleName:null,surname:"Hussain",slug:"dil-hussain",fullName:"Dil Hussain",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/605/images/system/605.jpg",biography:"Dr. Dil Muhammad Akbar Hussain is a professor of Electronics Engineering & Computer Science at the Department of Energy Technology, Aalborg University Denmark. Professor Akbar has a Master degree in Digital Electronics from Govt. College University, Lahore Pakistan and a P-hD degree in Control Engineering from the School of Engineering and Applied Sciences, University of Sussex United Kingdom. Aalborg University has Two Satellite Campuses, one in Copenhagen (Aalborg University Copenhagen) and the other in Esbjerg (Aalborg University Esbjerg).\n· He is a member of prestigious IEEE (Institute of Electrical and Electronics Engineers), and IAENG (International Association of Engineers) organizations. \n· He is the chief Editor of the Journal of Software Engineering.\n· He is the member of the Editorial Board of International Journal of Computer Science and Software Technology (IJCSST) and International Journal of Computer Engineering and Information Technology. \n· He is also the Editor of Communication in Computer and Information Science CCIS-20 by Springer.\n· Reviewer For Many Conferences\nHe is the lead person in making collaboration agreements between Aalborg University and many universities of Pakistan, for which the MOU’s (Memorandum of Understanding) have been signed.\nProfessor Akbar is working in Academia since 1990, he started his career as a Lab demonstrator/TA at the University of Sussex. After finishing his P. hD degree in 1992, he served in the Industry as a Scientific Officer and continued his academic career as a visiting scholar for a number of educational institutions. In 1996 he joined National University of Science & Technology Pakistan (NUST) as an Associate Professor; NUST is one of the top few universities in Pakistan. In 1999 he joined an International Company Lineo Inc, Canada as Manager Compiler Group, where he headed the group for developing Compiler Tool Chain and Porting of Operating Systems for the BLACKfin processor. The processor development was a joint venture by Intel and Analog Devices. In 2002 Lineo Inc., was taken over by another company, so he joined Aalborg University Denmark as an Assistant Professor.\nProfessor Akbar has truly a multi-disciplined career and he continued his legacy and making progress in many areas of his interests both in teaching and research. He has contributed in stochastic estimation of control area especially, in the Multiple Target Tracking and Interactive Multiple Model (IMM) research, Ball & Beam Control Problem, Robotics, Levitation Control. He has contributed in developing Algorithms for Fingerprint Matching, Computer Vision and Face Recognition. He has been supervising Pattern Recognition, Formal Languages and Distributed Processing projects for several years. He has reviewed many books on Management, Computer Science. Currently, he is an active and permanent reviewer for many international conferences and symposia and the program committee member for many international conferences.\nIn teaching he has taught the core computer science subjects like, Digital Design, Real Time Embedded System Programming, Operating Systems, Software Engineering, Data Structures, Databases, Compiler Construction. 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Beloborodova",profilePictureURL:"https://mts.intechopen.com/storage/users/199461/images/system/199461.jpg",institutionString:"Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology",institution:null}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"9731",title:"Oxidoreductase",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/9731.jpg",slug:"oxidoreductase",publishedDate:"February 17th 2021",editedByType:"Edited by",bookSignature:"Mahmoud Ahmed Mansour",hash:"852e6f862c85fc3adecdbaf822e64e6e",volumeInSeries:19,fullTitle:"Oxidoreductase",editors:[{id:"224662",title:"Prof.",name:"Mahmoud Ahmed",middleName:null,surname:"Mansour",slug:"mahmoud-ahmed-mansour",fullName:"Mahmoud Ahmed Mansour",profilePictureURL:"https://mts.intechopen.com/storage/users/224662/images/system/224662.jpg",institutionString:"King Saud bin Abdulaziz University for Health Sciences",institution:{name:"King Saud bin Abdulaziz University for Health Sciences",institutionURL:null,country:{name:"Saudi Arabia"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"9742",title:"Ubiquitin",subtitle:"Proteasome Pathway",coverURL:"https://cdn.intechopen.com/books/images_new/9742.jpg",slug:"ubiquitin-proteasome-pathway",publishedDate:"December 9th 2020",editedByType:"Edited by",bookSignature:"Xianquan Zhan",hash:"af6880d3a5571da1377ac8f6373b9e82",volumeInSeries:18,fullTitle:"Ubiquitin - Proteasome Pathway",editors:[{id:"223233",title:"Prof.",name:"Xianquan",middleName:null,surname:"Zhan",slug:"xianquan-zhan",fullName:"Xianquan Zhan",profilePictureURL:"https://mts.intechopen.com/storage/users/223233/images/system/223233.png",institutionString:"Shandong First Medical University",institution:{name:"Affiliated Hospital of Shandong Academy of Medical Sciences",institutionURL:null,country:{name:"China"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"9002",title:"Glutathione System and Oxidative Stress in Health and Disease",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/9002.jpg",slug:"glutathione-system-and-oxidative-stress-in-health-and-disease",publishedDate:"August 26th 2020",editedByType:"Edited by",bookSignature:"Margarete Dulce Bagatini",hash:"127defed0a50ad5ed92338dc96e1e10e",volumeInSeries:17,fullTitle:"Glutathione System and Oxidative Stress in Health and Disease",editors:[{id:"217850",title:"Dr.",name:"Margarete Dulce",middleName:null,surname:"Bagatini",slug:"margarete-dulce-bagatini",fullName:"Margarete Dulce Bagatini",profilePictureURL:"https://mts.intechopen.com/storage/users/217850/images/system/217850.jpeg",institutionString:"Universidade Federal da Fronteira Sul",institution:{name:"Universidade Federal da Fronteira Sul",institutionURL:null,country:{name:"Brazil"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},subseriesFiltersForPublishedBooks:[{group:"subseries",caption:"Proteomics",value:18,count:3},{group:"subseries",caption:"Metabolism",value:17,count:6},{group:"subseries",caption:"Cell and Molecular Biology",value:14,count:8},{group:"subseries",caption:"Chemical Biology",value:15,count:10}],publicationYearFilters:[{group:"publicationYear",caption:"2022",value:2022,count:3},{group:"publicationYear",caption:"2021",value:2021,count:7},{group:"publicationYear",caption:"2020",value:2020,count:12},{group:"publicationYear",caption:"2019",value:2019,count:3},{group:"publicationYear",caption:"2018",value:2018,count:2}],authors:{paginationCount:301,paginationItems:[{id:"116250",title:"Dr.",name:"Nima",middleName:null,surname:"Rezaei",slug:"nima-rezaei",fullName:"Nima Rezaei",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/116250/images/system/116250.jpg",biography:"Professor Nima Rezaei obtained an MD from Tehran University of Medical Sciences, Iran. He also obtained an MSc in Molecular and Genetic Medicine, and a Ph.D. in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also completed a short-term fellowship in Pediatric Clinical Immunology and Bone Marrow Transplantation at Newcastle General Hospital, England. Dr. Rezaei is a Full Professor of Immunology and Vice Dean of International Affairs and Research, at the School of Medicine, Tehran University of Medical Sciences, and the co-founder and head of the Research Center for Immunodeficiencies. He is also the founding president of the Universal Scientific Education and Research Network (USERN). Dr. Rezaei has directed more than 100 research projects and has designed and participated in several international collaborative projects. He is an editor, editorial assistant, or editorial board member of more than forty international journals. He has edited more than 50 international books, presented more than 500 lectures/posters in congresses/meetings, and published more than 1,100 scientific papers in international journals.",institutionString:"Tehran University of Medical Sciences",institution:{name:"Tehran University of Medical Sciences",country:{name:"Iran"}}},{id:"180733",title:"Dr.",name:"Jean",middleName:null,surname:"Engohang-Ndong",slug:"jean-engohang-ndong",fullName:"Jean Engohang-Ndong",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/180733/images/system/180733.png",biography:"Dr. Jean Engohang-Ndong was born and raised in Gabon. After obtaining his Associate Degree of Science at the University of Science and Technology of Masuku, Gabon, he continued his education in France where he obtained his BS, MS, and Ph.D. in Medical Microbiology. He worked as a post-doctoral fellow at the Public Health Research Institute (PHRI), Newark, NJ for four years before accepting a three-year faculty position at Brigham Young University-Hawaii. Dr. Engohang-Ndong is a tenured faculty member with the academic rank of Full Professor at Kent State University, Ohio, where he teaches a wide range of biological science courses and pursues his research in medical and environmental microbiology. Recently, he expanded his research interest to epidemiology and biostatistics of chronic diseases in Gabon.",institutionString:"Kent State University",institution:{name:"Kent State University",country:{name:"United States of America"}}},{id:"188773",title:"Prof.",name:"Emmanuel",middleName:null,surname:"Drouet",slug:"emmanuel-drouet",fullName:"Emmanuel Drouet",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/188773/images/system/188773.png",biography:"Emmanuel Drouet, PharmD, is a Professor of Virology at the Faculty of Pharmacy, the University Grenoble-Alpes, France. As a head scientist at the Institute of Structural Biology in Grenoble, Dr. Drouet’s research investigates persisting viruses in humans (RNA and DNA viruses) and the balance with our host immune system. He focuses on these viruses’ effects on humans (both their impact on pathology and their symbiotic relationships in humans). He has an excellent track record in the herpesvirus field, and his group is engaged in clinical research in the field of Epstein-Barr virus diseases. He is the editor of the online Encyclopedia of Environment and he coordinates the Universal Health Coverage education program for the BioHealth Computing Schools of the European Institute of Science.",institutionString:null,institution:{name:"Grenoble Alpes University",country:{name:"France"}}},{id:"131400",title:"Prof.",name:"Alfonso J.",middleName:null,surname:"Rodriguez-Morales",slug:"alfonso-j.-rodriguez-morales",fullName:"Alfonso J. Rodriguez-Morales",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/131400/images/system/131400.png",biography:"Dr. Rodriguez-Morales is an expert in tropical and emerging diseases, particularly zoonotic and vector-borne diseases (especially arboviral diseases). He is the president of the Travel Medicine Committee of the Pan-American Infectious Diseases Association (API), as well as the president of the Colombian Association of Infectious Diseases (ACIN). He is a member of the Committee on Tropical Medicine, Zoonoses, and Travel Medicine of ACIN. He is a vice-president of the Latin American Society for Travel Medicine (SLAMVI) and a Member of the Council of the International Society for Infectious Diseases (ISID). Since 2014, he has been recognized as a Senior Researcher, at the Ministry of Science of Colombia. He is a professor at the Faculty of Medicine of the Fundacion Universitaria Autonoma de las Americas, in Pereira, Risaralda, Colombia. He is an External Professor, Master in Research on Tropical Medicine and International Health, Universitat de Barcelona, Spain. He is also a professor at the Master in Clinical Epidemiology and Biostatistics, Universidad Científica del Sur, Lima, Peru. In 2021 he has been awarded the “Raul Isturiz Award” Medal of the API. Also, in 2021, he was awarded with the “Jose Felix Patiño” Asclepius Staff Medal of the Colombian Medical College, due to his scientific contributions to COVID-19 during the pandemic. He is currently the Editor in Chief of the journal Travel Medicine and Infectious Diseases. His Scopus H index is 47 (Google Scholar H index, 68).",institutionString:"Institución Universitaria Visión de las Américas, Colombia",institution:null},{id:"332819",title:"Dr.",name:"Chukwudi Michael",middleName:"Michael",surname:"Egbuche",slug:"chukwudi-michael-egbuche",fullName:"Chukwudi Michael Egbuche",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/332819/images/14624_n.jpg",biography:"I an Dr. Chukwudi Michael Egbuche. I am a Senior Lecturer in the Department of Parasitology and Entomology, Nnamdi Azikiwe University, Awka.",institutionString:null,institution:{name:"Nnamdi Azikiwe University",country:{name:"Nigeria"}}},{id:"284232",title:"Mr.",name:"Nikunj",middleName:"U",surname:"Tandel",slug:"nikunj-tandel",fullName:"Nikunj Tandel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/284232/images/8275_n.jpg",biography:'Mr. Nikunj Tandel has completed his Master\'s degree in Biotechnology from VIT University, India in the year of 2012. He is having 8 years of research experience especially in the field of malaria epidemiology, immunology, and nanoparticle-based drug delivery system against the infectious diseases, autoimmune disorders and cancer. He has worked for the NIH funded-International Center of Excellence in Malaria Research project "Center for the study of complex malaria in India (CSCMi)" in collaboration with New York University. The preliminary objectives of the study are to understand and develop the evidence-based tools and interventions for the control and prevention of malaria in different sites of the INDIA. Alongside, with the help of next-generation genomics study, the team has studied the antimalarial drug resistance in India. Further, he has extended his research in the development of Humanized mice for the study of liver-stage malaria and identification of molecular marker(s) for the Artemisinin resistance. At present, his research focuses on understanding the role of B cells in the activation of CD8+ T cells in malaria. Received the CSIR-SRF (Senior Research Fellow) award-2018, FIMSA (Federation of Immunological Societies of Asia-Oceania) Travel Bursary award to attend the IUIS-IIS-FIMSA Immunology course-2019',institutionString:"Nirma University",institution:{name:"Nirma University",country:{name:"India"}}},{id:"334383",title:"Ph.D.",name:"Simone",middleName:"Ulrich",surname:"Ulrich Picoli",slug:"simone-ulrich-picoli",fullName:"Simone Ulrich Picoli",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/334383/images/15919_n.jpg",biography:"Graduated in Pharmacy from Universidade Luterana do Brasil (1999), Master in Agricultural and Environmental Microbiology from Federal University of Rio Grande do Sul (2002), Specialization in Clinical Microbiology from Universidade de São Paulo, USP (2007) and PhD in Sciences in Gastroenterology and Hepatology (2012). She is currently an Adjunct Professor at Feevale University in Medicine and Biomedicine courses and a permanent professor of the Academic Master\\'s Degree in Virology. She has experience in the field of Microbiology, with an emphasis on Bacteriology, working mainly on the following topics: bacteriophages, bacterial resistance, clinical microbiology and food microbiology.",institutionString:null,institution:{name:"Universidade Feevale",country:{name:"Brazil"}}},{id:"229220",title:"Dr.",name:"Amjad",middleName:"Islam",surname:"Aqib",slug:"amjad-aqib",fullName:"Amjad Aqib",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/229220/images/system/229220.png",biography:"Dr. Amjad Islam Aqib obtained a DVM and MSc (Hons) from University of Agriculture Faisalabad (UAF), Pakistan, and a PhD from the University of Veterinary and Animal Sciences Lahore, Pakistan. Dr. Aqib joined the Department of Clinical Medicine and Surgery at UAF for one year as an assistant professor where he developed a research laboratory designated for pathogenic bacteria. Since 2018, he has been Assistant Professor/Officer in-charge, Department of Medicine, Manager Research Operations and Development-ORIC, and President One Health Club at Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Pakistan. He has nearly 100 publications to his credit. His research interests include epidemiological patterns and molecular analysis of antimicrobial resistance and modulation and vaccine development against animal pathogens of public health concern.",institutionString:"Cholistan University of Veterinary and Animal Sciences",institution:null},{id:"62900",title:"Prof.",name:"Fethi",middleName:null,surname:"Derbel",slug:"fethi-derbel",fullName:"Fethi Derbel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/62900/images/system/62900.jpeg",biography:"Professor Fethi Derbel was born in 1960 in Tunisia. He received his medical degree from the Sousse Faculty of Medicine at Sousse, University of Sousse, Tunisia. He completed his surgical residency in General Surgery at the University Hospital Farhat Hached of Sousse and was a member of the Unit of Liver Transplantation in the University of Rennes, France. He then worked in the Department of Surgery at the Sahloul University Hospital in Sousse. Professor Derbel is presently working at the Clinique les Oliviers, Sousse, Tunisia. His hospital activities are mostly concerned with laparoscopic, colorectal, pancreatic, hepatobiliary, and gastric surgery. He is also very interested in hernia surgery and performs ventral hernia repairs and inguinal hernia repairs. He has been a member of the GREPA and Tunisian Hernia Society (THS). During his residency, he managed patients suffering from diabetic foot, and he was very interested in this pathology. For this reason, he decided to coordinate a book project dealing with the diabetic foot. Professor Derbel has published many articles in journals and collaborates intensively with IntechOpen Access Publisher as an editor.",institutionString:"Clinique les Oliviers",institution:null},{id:"300144",title:"Dr.",name:"Meriem",middleName:null,surname:"Braiki",slug:"meriem-braiki",fullName:"Meriem Braiki",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/300144/images/system/300144.jpg",biography:"Dr. Meriem Braiki is a specialist in pediatric surgeon from Tunisia. She was born in 1985. She received her medical degree from the University of Medicine at Sousse, Tunisia. She achieved her surgical residency training periods in Pediatric Surgery departments at University Hospitals in Monastir, Tunis and France.\r\nShe is currently working at the Pediatric surgery department, Sidi Bouzid Hospital, Tunisia. Her hospital activities are mostly concerned with laparoscopic, parietal, urological and digestive surgery. She has published several articles in diffrent journals.",institutionString:"Sidi Bouzid Regional Hospital",institution:null},{id:"229481",title:"Dr.",name:"Erika M.",middleName:"Martins",surname:"de Carvalho",slug:"erika-m.-de-carvalho",fullName:"Erika M. de Carvalho",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/229481/images/6397_n.jpg",biography:null,institutionString:null,institution:{name:"Oswaldo Cruz Foundation",country:{name:"Brazil"}}},{id:"186537",title:"Prof.",name:"Tonay",middleName:null,surname:"Inceboz",slug:"tonay-inceboz",fullName:"Tonay Inceboz",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/186537/images/system/186537.jfif",biography:"I was graduated from Ege University of Medical Faculty (Turkey) in 1988 and completed his Med. PhD degree in Medical Parasitology at the same university. I became an Associate Professor in 2008 and Professor in 2014. I am currently working as a Professor at the Department of Medical Parasitology at Dokuz Eylul University, Izmir, Turkey.\n\nI have given many lectures, presentations in different academic meetings. I have more than 60 articles in peer-reviewed journals, 18 book chapters, 1 book editorship.\n\nMy research interests are Echinococcus granulosus, Echinococcus multilocularis (diagnosis, life cycle, in vitro and in vivo cultivation), and Trichomonas vaginalis (diagnosis, PCR, and in vitro cultivation).",institutionString:"Dokuz Eylül University",institution:{name:"Dokuz Eylül University",country:{name:"Turkey"}}},{id:"71812",title:"Prof.",name:"Hanem Fathy",middleName:"Fathy",surname:"Khater",slug:"hanem-fathy-khater",fullName:"Hanem Fathy Khater",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/71812/images/1167_n.jpg",biography:"Prof. Khater is a Professor of Parasitology at Benha University, Egypt. She studied for her doctoral degree, at the Department of Entomology, College of Agriculture, Food and Natural Resources, University of Missouri, Columbia, USA. She has completed her Ph.D. degrees in Parasitology in Egypt, from where she got the award for “the best scientific Ph.D. dissertation”. She worked at the School of Biological Sciences, Bristol, England, the UK in controlling insects of medical and veterinary importance as a grant from Newton Mosharafa, the British Council. Her research is focused on searching of pesticides against mosquitoes, house flies, lice, green bottle fly, camel nasal botfly, soft and hard ticks, mites, and the diamondback moth as well as control of several parasites using safe and natural materials to avoid drug resistances and environmental contamination.",institutionString:null,institution:{name:"Banha University",country:{name:"Egypt"}}},{id:"99780",title:"Prof.",name:"Omolade",middleName:"Olayinka",surname:"Okwa",slug:"omolade-okwa",fullName:"Omolade Okwa",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/99780/images/system/99780.jpg",biography:"Omolade Olayinka Okwa is presently a Professor of Parasitology at Lagos State University, Nigeria. She has a PhD in Parasitology (1997), an MSc in Cellular Parasitology (1992), and a BSc (Hons) Zoology (1990) all from the University of Ibadan, Nigeria. She teaches parasitology at the undergraduate and postgraduate levels. She was a recipient of a Commonwealth fellowship supported by British Council tenable at the Centre for Entomology and Parasitology (CAEP), Keele University, United Kingdom between 2004 and 2005. She was awarded an Honorary Visiting Research Fellow at the same university from 2005 to 2007. \nShe has been an external examiner to the Department of Veterinary Microbiology and Parasitology, University of Ibadan, MSc programme between 2010 and 2012. She is a member of the Nigerian Society of Experimental Biology (NISEB), Parasitology and Public Health Society of Nigeria (PPSN), Science Association of Nigeria (SAN), Zoological Society of Nigeria (ZSN), and is Vice Chairperson of the Organisation of Women in Science (OWSG), LASU chapter. She served as Head of Department of Zoology and Environmental Biology, Lagos State University from 2007 to 2010 and 2014 to 2016. She is a reviewer for several local and international journals such as Unilag Journal of Science, Libyan Journal of Medicine, Journal of Medicine and Medical Sciences, and Annual Research and Review in Science. \nShe has authored 45 scientific research publications in local and international journals, 8 scientific reviews, 4 books, and 3 book chapters, which includes the books “Malaria Parasites” and “Malaria” which are IntechOpen access publications.",institutionString:"Lagos State University",institution:{name:"Lagos State University",country:{name:"Nigeria"}}},{id:"273100",title:"Dr.",name:"Vijay",middleName:null,surname:"Gayam",slug:"vijay-gayam",fullName:"Vijay Gayam",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/273100/images/system/273100.jpeg",biography:"Dr. Vijay Bhaskar Reddy Gayam is currently practicing as an internist at Interfaith Medical Center in Brooklyn, New York, USA. He is also a Clinical Assistant Professor at the SUNY Downstate University Hospital and Adjunct Professor of Medicine at the American University of Antigua. He is a holder of an M.B.B.S. degree bestowed to him by Osmania Medical College and received his M.D. at Interfaith Medical Center. His career goals thus far have heavily focused on direct patient care, medical education, and clinical research. He currently serves in two leadership capacities; Assistant Program Director of Medicine at Interfaith Medical Center and as a Councilor for the American\r\nFederation for Medical Research. As a true academician and researcher, he has more than 50 papers indexed in international peer-reviewed journals. He has also presented numerous papers in multiple national and international scientific conferences. His areas of research interest include general internal medicine, gastroenterology and hepatology. He serves as an editor, editorial board member and reviewer for multiple international journals. His research on Hepatitis C has been very successful and has led to multiple research awards, including the 'Equity in Prevention and Treatment Award” from the New York Department of Health Viral Hepatitis Symposium (2018) and the 'Presidential Poster Award” awarded to him by the American College of Gastroenterology (2018). He was also awarded 'Outstanding Clinician in General Medicine” by Venus International Foundation for his extensive research expertise and services, perform over and above the standard expected in the advancement of healthcare, patient safety and quality of care.",institutionString:"Interfaith Medical Center",institution:{name:"Interfaith Medical Center",country:{name:"United States of America"}}},{id:"93517",title:"Dr.",name:"Clement",middleName:"Adebajo",surname:"Meseko",slug:"clement-meseko",fullName:"Clement Meseko",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/93517/images/system/93517.jpg",biography:"Dr. Clement Meseko obtained DVM and PhD degree in Veterinary Medicine and Virology respectively. He has worked for over 20 years in both private and public sectors including the academia, contributing to knowledge and control of infectious disease. Through the application of epidemiological skill, classical and molecular virological skills, he investigates viruses of economic and public health importance for the mitigation of the negative impact on people, animal and the environment in the context of Onehealth. \r\nDr. Meseko’s field experience on animal and zoonotic diseases and pathogen dynamics at the human-animal interface over the years shaped his carrier in research and scientific inquiries. He has been part of the investigation of Highly Pathogenic Avian Influenza incursions in sub Saharan Africa and monitors swine Influenza (Pandemic influenza Virus) agro-ecology and potential for interspecies transmission. He has authored and reviewed a number of journal articles and book chapters.",institutionString:"National Veterinary Research Institute",institution:{name:"National Veterinary Research Institute",country:{name:"Nigeria"}}},{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",biography:"Professor Dr. Shailendra K. Saxena is a vice dean and professor at King George's Medical University, Lucknow, India. His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research work has been published in various high-impact factor journals (Science, PNAS, Nature Medicine) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. Dr. Saxena is a fellow of various international societies/academies including the Royal College of Pathologists, United Kingdom; Royal Society of Medicine, London; Royal Society of Biology, United Kingdom; Royal Society of Chemistry, London; and Academy of Translational Medicine Professionals, Austria. He was named a Global Leader in Science by The Scientist. He is also an international opinion leader/expert in vaccination for Japanese encephalitis by IPIC (UK).",institutionString:"King George's Medical University",institution:{name:"King George's Medical University",country:{name:"India"}}},{id:"94928",title:"Dr.",name:"Takuo",middleName:null,surname:"Mizukami",slug:"takuo-mizukami",fullName:"Takuo Mizukami",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/94928/images/6402_n.jpg",biography:null,institutionString:null,institution:{name:"National Institute of Infectious Diseases",country:{name:"Japan"}}},{id:"233433",title:"Dr.",name:"Yulia",middleName:null,surname:"Desheva",slug:"yulia-desheva",fullName:"Yulia Desheva",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/233433/images/system/233433.png",biography:"Dr. Yulia Desheva is a leading researcher at the Institute of Experimental Medicine, St. Petersburg, Russia. She is a professor in the Stomatology Faculty, St. Petersburg State University. She has expertise in the development and evaluation of a wide range of live mucosal vaccines against influenza and bacterial complications. 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Topics include, but are not limited to: Advanced techniques of cellular and molecular biology (Molecular methodologies, imaging techniques, and bioinformatics); Biological activities at the molecular level; Biological processes of cell functions, cell division, senescence, maintenance, and cell death; Biomolecules interactions; Cancer; Cell biology; Chemical biology; Computational biology; Cytochemistry; Developmental biology; Disease mechanisms and therapeutics; DNA, and RNA metabolism; Gene functions, genetics, and genomics; Genetics; Immunology; Medical microbiology; Molecular biology; Molecular genetics; Molecular processes of cell and organelle dynamics; Neuroscience; Protein biosynthesis, degradation, and functions; Regulation of molecular interactions in a cell; Signalling networks and system biology; Structural biology; Virology and microbiology.",annualVolume:11410,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/14.jpg",editor:{id:"165627",title:"Dr.",name:"Rosa María",middleName:null,surname:"Martínez-Espinosa",fullName:"Rosa María Martínez-Espinosa",profilePictureURL:"https://mts.intechopen.com/storage/users/165627/images/system/165627.jpeg",institutionString:null,institution:{name:"University of Alicante",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"79367",title:"Dr.",name:"Ana Isabel",middleName:null,surname:"Flores",fullName:"Ana Isabel Flores",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRpIOQA0/Profile_Picture_1632418099564",institutionString:null,institution:{name:"Hospital Universitario 12 De Octubre",institutionURL:null,country:{name:"Spain"}}},{id:"328234",title:"Ph.D.",name:"Christian",middleName:null,surname:"Palavecino",fullName:"Christian Palavecino",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000030DhEhQAK/Profile_Picture_1628835318625",institutionString:null,institution:{name:"Central University of Chile",institutionURL:null,country:{name:"Chile"}}},{id:"186585",title:"Dr.",name:"Francisco Javier",middleName:null,surname:"Martin-Romero",fullName:"Francisco Javier Martin-Romero",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSB3HQAW/Profile_Picture_1631258137641",institutionString:null,institution:{name:"University of Extremadura",institutionURL:null,country:{name:"Spain"}}}]},{id:"15",title:"Chemical Biology",keywords:"Phenolic Compounds, Essential Oils, Modification of Biomolecules, Glycobiology, Combinatorial Chemistry, Therapeutic peptides, Enzyme Inhibitors",scope:"Chemical biology spans the fields of chemistry and biology involving the application of biological and chemical molecules and techniques. 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Behind these definitions are hidden all the aspects of normal and pathological functioning of all processes that the topic ‘Metabolism’ will cover within the Biochemistry Series. 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Thus proteomics, an area of research that detects all protein forms expressed in an organism, including splice isoforms and post-translational modifications, is more suitable than genomics for a comprehensive understanding of the biochemical processes that govern life. The most common proteomics applications are currently in the clinical field for the identification, in a variety of biological matrices, of biomarkers for diagnosis and therapeutic intervention of disorders. From the comparison of proteomic profiles of control and disease or different physiological states, which may emerge, changes in protein expression can provide new insights into the roles played by some proteins in human pathologies. Understanding how proteins function and interact with each other is another goal of proteomics that makes this approach even more intriguing. Specialized technology and expertise are required to assess the proteome of any biological sample. 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