\\n\\n
More than half of the publishers listed alongside IntechOpen (18 out of 30) are Social Science and Humanities publishers. IntechOpen is an exception to this as a leader in not only Open Access content but Open Access content across all scientific disciplines, including Physical Sciences, Engineering and Technology, Health Sciences, Life Science, and Social Sciences and Humanities.
\\n\\nOur breakdown of titles published demonstrates this with 47% PET, 31% HS, 18% LS, and 4% SSH books published.
\\n\\n“Even though ItechOpen has shown the potential of sci-tech books using an OA approach,” other publishers “have shown little interest in OA books.”
\\n\\nAdditionally, each book published by IntechOpen contains original content and research findings.
\\n\\nWe are honored to be among such prestigious publishers and we hope to continue to spearhead that growth in our quest to promote Open Access as a true pioneer in OA book publishing.
\\n\\n\\n\\n
\\n"}]',published:!0,mainMedia:{caption:"IntechOpen Maintains",originalUrl:"/media/original/113"}},components:[{type:"htmlEditorComponent",content:'
Simba Information has released its Open Access Book Publishing 2020 - 2024 report and has again identified IntechOpen as the world’s largest Open Access book publisher by title count.
\n\nSimba Information is a leading provider for market intelligence and forecasts in the media and publishing industry. The report, published every year, provides an overview and financial outlook for the global professional e-book publishing market.
\n\nIntechOpen, De Gruyter, and Frontiers are the largest OA book publishers by title count, with IntechOpen coming in at first place with 5,101 OA books published, a good 1,782 titles ahead of the nearest competitor.
\n\nSince the first Open Access Book Publishing report published in 2016, IntechOpen has held the top stop each year.
\n\n\n\nMore than half of the publishers listed alongside IntechOpen (18 out of 30) are Social Science and Humanities publishers. IntechOpen is an exception to this as a leader in not only Open Access content but Open Access content across all scientific disciplines, including Physical Sciences, Engineering and Technology, Health Sciences, Life Science, and Social Sciences and Humanities.
\n\nOur breakdown of titles published demonstrates this with 47% PET, 31% HS, 18% LS, and 4% SSH books published.
\n\n“Even though ItechOpen has shown the potential of sci-tech books using an OA approach,” other publishers “have shown little interest in OA books.”
\n\nAdditionally, each book published by IntechOpen contains original content and research findings.
\n\nWe are honored to be among such prestigious publishers and we hope to continue to spearhead that growth in our quest to promote Open Access as a true pioneer in OA book publishing.
\n\n\n\n
\n'}],latestNews:[{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"},{slug:"introducing-intechopen-book-series-a-new-publishing-format-for-oa-books-20210915",title:"Introducing IntechOpen Book Series - A New Publishing Format for OA Books"}]},book:{item:{type:"book",id:"2915",leadTitle:null,fullTitle:"Finite Element Analysis - Applications in Mechanical Engineering",title:"Finite Element Analysis",subtitle:"Applications in Mechanical Engineering",reviewType:"peer-reviewed",abstract:"In the past few decades, the Finite Element Analysis (FEA) has been developed into a key indispensable technology in the modeling and simulation of various engineering systems. 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\r\n\tAnimal models are used to understand physiological, biochemical, and pathological mechanisms of cells, tissues, organs, and systems, to elucidate inter-system relations, to develop new diagnostic methods for diseases or functional disorders, and to develop new strategies for their treatment. When considering the ethical and legal constraints, the need to use animal models maintains its importance from past to present. The success of the research depends on the suitability of the chosen model. For example, while single-celled organisms such as yeast are a convenient model for the study of basic eukaryotic cell functions such as cell cycle regulation, vesicular transport, protein folding, and DNA repair, simple invertebrates such as Caenorhabditis elegans or Drosophila are regarded as good models in studies examining the coordinated functions of genes related to signal transmission or protein-protein interactions. Simple vertebrates (zebrafish, frogs, etc.) or mammals (rat, mouse, rabbit, guinea pig, etc.) are used to establish human disease models or to explain their effects at the organism level. In addition, the use of experimental animals is quite common in experimental medicine research, especially in pharmaceutical developments and molecular pathway studies.
\r\n\r\n\tThis book aims to discuss current developments such as the definition of model animals, the purposes of using model animals and the diseases in which they are used, the selection of appropriate models and subjects, and the technological methods used in the experimental model.
",isbn:"978-1-80356-654-2",printIsbn:"978-1-80356-653-5",pdfIsbn:"978-1-80356-655-9",doi:null,price:0,priceEur:0,priceUsd:0,slug:null,numberOfPages:0,isOpenForSubmission:!0,isSalesforceBook:!1,hash:"13081c55758b6bbcd126c71df34bd4a2",bookSignature:"Dr. Mahmut Karapehlivan, Associate Prof. Volkan Gelen and Dr. Abdulsamed Kükürt",publishedDate:null,coverURL:"https://cdn.intechopen.com/books/images_new/11711.jpg",keywords:"Animal Care and Feeding, Breeding, Environment, Physiological Parameters, Biochemical Parameter, Genetic and Transgenic Animals, Neuronal Activity, Brain IRI, Renal IRI, Therapeutic Agents, Hepatotoxicity, Immunity",numberOfDownloads:null,numberOfWosCitations:0,numberOfCrossrefCitations:null,numberOfDimensionsCitations:null,numberOfTotalCitations:null,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"March 18th 2022",dateEndSecondStepPublish:"May 27th 2022",dateEndThirdStepPublish:"July 26th 2022",dateEndFourthStepPublish:"October 14th 2022",dateEndFifthStepPublish:"December 13th 2022",remainingDaysToSecondStep:"8 days",secondStepPassed:!1,currentStepOfPublishingProcess:2,editedByType:null,kuFlag:!1,biosketch:"Dr. Karapehlivan is part of the university senate of Kafkas University. 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He worked as an assistant professor in the Department of Biochemistry from 2004 to 2009. He earned the title of Associate Professor of Biochemistry in the field of Health Sciences in 2009. He was appointed Professor in 2014. He is currently working as a Professor in the Department of Biochemistry at Kafkas University Faculty of Medicine.",institutionString:"Kafkas University",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"2",totalChapterViews:"0",totalEditedBooks:"0",institution:{name:"Kafkas University",institutionURL:null,country:{name:"Turkey"}}}],coeditorOne:{id:"178366",title:"Associate Prof.",name:"Volkan",middleName:null,surname:"Gelen",slug:"volkan-gelen",fullName:"Volkan Gelen",profilePictureURL:"https://mts.intechopen.com/storage/users/178366/images/system/178366.jpg",biography:"Volkan Gelen is a Physiology specialist who received his veterinary degree from Kafkas University in 2011. Between 2011-2015, he worked as an assistant at Atatürk University, Faculty of Veterinary Medicine, Department of Physiology. In 2016, he joined Kafkas University, Faculty of Veterinary Medicine, Department of Physiology as an assistant professor. Dr. Gelen has been engaged in various academic activities at Kafkas University since 2016. There he completed 5 projects and has 3 ongoing projects. He has 60 articles published in scientific journals and 20 poster presentations in scientific congresses. 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The journey continues and new designs of systems and technologies emerge more each day, and in the last few decades, research in this field has expanded quite rapidly. Artificial intelligence tries to simulate human abilities with the help of machines. This challenge, launched at the famous Dartmouth conference in 1956, has attracted a great deal of interest and effort from the research community over the last 50 years. While the community has not been able to accomplish the euphoric expectations presented at that conference even after so many years, a good number of accomplishments were achieved in this simulation of human capabilities with computers, embracing the progression of the artificial intelligence field.
One of the cornerstones of simulating human abilities, without any doubt, is communication. Communication between humans, between machines, or between humans and machines can be realized in this scenario. In communication theory, communication between humans has indeed been studied for several years, communication between machines is still currently a major topic in conferences, with a peculiar focus on ontologies and communication acts. Finally, in the Human-Computer Interaction discipline, communication between humans and machines is being studied. The design, implementation and assessment of user interfaces are discussed in this discipline.
From the first command-based user interfaces to the most advanced graphical ones, the brief, but extremely active, history of computer science has witnessed a real revolution in user interfaces. The computational balance is now leaning towards interaction, cultivating an increasing interest in user interfaces. At the same time, the growing power and sophistication of user interfaces is encouraging the creation of techniques and modalities of interaction closer to human beings’ cognitive models. In the pursuit of these goals, several different artificial intelligence methods have been incorporated into user interfaces over the last fifty years to provide a more natural and efficient interaction between humans and computers.
One of the key parts of an application is the user interface. If it is designed correctly, when communicating with the computer, the user may feel relaxed. On the other hand, if an application is capable of performing the tasks for which it was intended, the application would still not be acceptable to users unless it is capable of interacting in an intelligible and functional way with the user. There is a real interest in enhancing communication between the user and the machine within the Human-Computer Interaction group, recognized by the large number of researchers dedicated to the study of techniques intended to improve usability [1] in a user interface.
The Human Computer Interaction research group is looking for how to enhance the user’s feeling from the user interface in the quest to build user interfaces with a high degree of usability. One main problem to be tackled in this pursuit is to make the interaction even more natural. This growing interest in making interaction even more natural means raising the standard of communication between humans and machines. The fundamental concepts of natural interaction have led to the exploration and implementation of a large number of techniques in interaction design coming from Artificial Intelligence, enabling, among many other things, more detailed responses to the actions of users. The term Intelligent User Interfaces have been created by this integration of Artificial Intelligence techniques within Human-Interaction Techniques, where this work is immersed.
The framework for the design of situation-aware interfaces are also covered in this chapter, in such a way that input information (context and environmental indications) can be specifically taken into consideration in the task specification [2]. It is believed that the designer adds abstract UI components to the task model to improve a concrete user interface (UI). This information is platform-independent, so that this information can ultimately be used by the rendering back-end to build a specific UI for different platforms. The next phase includes developing the model for dialogue. In order to simplify the work of designers, designers can be helped by automatically creating the state and transformations between the different individual dialogues. The method provides an algorithm to measure the various dialogues and transformations from the mission definition between dialogues. These transformations can be modified, incorporated or omitted by designers according to the outcome of a previous testing stage or the expertise of the designers. This allows situation-aware UI programmers to exploit transformations caused by changes in the situation. Therefore, programmers have power over the effect of the condition on the UIs’ usability. In [3] research focuses on developing experiences of visual context-aware services by integrating approaches from computer vision and artificial intelligence. It has close connections to the field of intelligent user interfaces.
The touchscreen keyboard is the most prevalent intelligent user interface on modern cell phones, and it is vital for mobile communication. Working to develop smarter, more effective, easy-to-learn, and enjoyable-to-use keyboards has raised a slew of intriguing IUI interface and research questions [4]. The progress and open research questions over the last decade in text input, emphasis on and directly dealt with through publications, including robotics and estimation cost-benefit equations [5], the significance of human performance models in the creation of error-correction algorithms and the potential of machine/statistical intelligence [6, 7, 8, 9, 10, 11], the ramifications of spatial scaling from a phone to a watch on human-machine labour separation, consumer behaviour and learning creativity, and the complexities of assessing the longitudinal impact of personalization and adaptation are discussed in [12, 13, 14, 15, 16, 17]. The aim of this study is to show that intelligent user interfaces, or the integration of artificial intelligence and human factors, are the future of human-computer interaction and information technology in general.
By varying decision factors’ forms, numbers, and values, this article [18] provides a mechanism for adaptive, measurable decision making for Multiple Attribute Decision Making (MADM). This research can be used to help designers create intelligent user interfaces for HCI decision-making applications that respond to user experience and decision-making efficiency. In [19], a Genetic Programming-based technology is proposed for automating crucial design phases. Designers can specify simple content elements and ways to merge them in this method, which will then be automatically composed and checked with actual users by a genetic algorithm to find optimal compositions.
The idea of Human-Computer Interaction/Interfacing (HCI) was automatically represented with the advent of the computer or, more generally, the system itself, also referred to as Man-Machine Interaction or Interfacing. In fact, the explanation is straightforward: most advanced machines are useless unless men can use them properly. The main ideas that should be considered in the development of HCI clearly present in this simple argument: functionality and usability [20].
In the end, why a system is actually built can be determined by what the system can really do, i.e. how a system’s function can assist in achieving the system’s purpose. A system’s functionality is characterized by the collection of actions or services it offers its users with. After all, the functionality value is only observable until it becomes feasible for the user to be used effectively [21]. The usability of a system with any functionality is the extent and degree to which the system can be used easily and reasonably by certain users to achieve specific objectives. If there is an appropriate equilibrium between the functionality and usability of a system, the real productivity of a system is achieved [22].
Taking these definitions into account and knowing that in this context, the term system, machine and computer are often used interchangeably, HCI is a design that should build a match between the user, the machine and the services needed in order to achieve a certain output both in terms of quality of service and optimality [23]. Most of it is subjective and context based to decide what makes a certain HCI design successful. An aircraft model design tool, for instance, must have precision in the display and design of the components, whereas graphics editing software doesn’t really require such accuracy. The technologies available may also have an effect on how various types of HCI are configured for the same reason. For example, commands, menus, graphical user interfaces (GUIs) or virtual reality can be used to access the information on a given device. A more detailed description of current techniques and technologies used to communicate with computers and the latest developments in the field is provided in the next section.
Intelligent user interfaces are human-machine interfaces whose purpose is to enhance the performance, affectivity, naturalness and, in general, usability of interactions between humans and machines representing, reasoning or performing on a collection of models (user, domain, dialog, voice, functions, etc.). The design of user interfaces is a multidisciplinary challenge due to the numerous models coming from different disciplines (see Figure 1). Artificial Intelligence leads to developing collaboration with intelligence modeling methods, Software Engineering corresponds to coherent systems, notations and formal languages. Consequently, the user’s concern leads to Human-Computer Interaction, and hence the strategies for designing practical user interfaces.
Various disciplines in the conception of intelligent user interfaces [
In order to fulfill the key purpose of intelligent user interfaces and to help them in various situations, they need to be able to reflect the information they have about users, the activities they are allowed to do across the user interface, the usage sense in which the user communicates with the program and has the ability to properly interpret the inputs and produce the outputs based on all the data gathered and the information they have [25]. The topic of usage is generally defined by presenting a model of the application users’ strengths, skills and interests, the channels on which those users communicate with the application (both the hardware and the software platform), and the physical world in which the interaction takes place, such as luminosity, noise level, etc. In [26], the task actually performed by the client is often included as a first order element in the scope of use. Since the current role is included in the framework of use, given a particular context of use, it is possible to better explain the reactions the machine would give. It can, for example, be used to build context-sensitive support systems quickly. It is very helpful to include the task in the context of use. It is not always feasible, though, to provide a high level of assurance about what the individual is actually carrying out. According to the interaction data obtained from the client, the authors add certain heuristics to a task model to figure out which is the task that is actually being done. The heuristics work on the premise that the possible tasks that the user executes at a given time are just the set of tasks “enabled” in the actual presentation in which the user communicates at all times [27].
In Figure 2 a few of the most critical issues encountered in intelligent user interfaces are illustrated [28]. These challenges are targeted at achieving the ultimate target of intelligent user interfaces: improving the overall usability of the machine.
The most common objectives seen in intelligent user interfaces [
As in Figure 2 the reader will observe that certain human capacities are included, such as understanding, adaptation, logic or simulation of the world. Many of those strengths are study lines established from the very beginning of this field of Artificial Intelligence. Many academic reports on artificial intelligence claims that intelligence is a program that can be executed regardless of the platform on which it is executed, irrespective of whether it is a machine or a brain. Two models, the user conceptual and the execution of one of the machines, must create a sort of equilibrium and comprehension when the user communicates with an item. The user uses a concrete vocabulary of operation defined by the input devices and the metaphor for which the user interface has been developed. On the other side, by conforming the contents, displaying it, the artifact must interpret the feedback and respond to the interaction, and it should also be able to determine the interaction mechanism itself and make conclusions as to how useful it is.
There are several areas of Artificial Intelligence that bring approaches, strategies and ideas of vital importance to the development of intelligent user interfaces. Methods for providing learning capacities such as neural networks or Bayesian networks can be used in Artificial Intelligence, knowledge representation methods such as semantic networks or frames, decision models such as fuzzy logic, expert systems, case-based reasoning and decision trees, etc. We may work on the user interface by applying these inputs to the intelligent user interface by facilitating transformation, making its use simpler, analyzing interaction, simulating activities, leading the user or assisting the developer of the user interface.
The most recent HCI study is unquestionably ubiquitous computing (Ubicomp). The phrase frequently used by ambient intelligence and pervasive computation interchangeably, refers to the ultimate human-computer interface techniques, which are the elimination of a desktop and the integrating of the computer in the environment in order to make it unseen to humans when covering them everywhere. Mark Weiser first proposed the concept of ubiquitous computing during his time as chief technologist at Xerox PARC’s Computer Science Lab in 1998. His vision was to incorporate machines into the world and ordinary objects anywhere so that individuals could connect with several computers at the same time because they are hidden to them and communicate with each other wirelessly [29].
The Third Era of computation has also been called Ubicomp. The first era was the mainframe era, with one machine and several people. Then it was the Second Era, one user, one computer, named the PC era, and now Ubicomp introduces more machines, one person era [29]. The major developments in computation are seen in Figure 3.
Major trends in computing [
The predominant trend since some years ago is model-based user interface development (MB-UID) in software product engineering and user interface is not an exception [30, 31]. The key concept behind this pattern is to define a set of templates representing the characteristics of the user, the activities, the domain, the sense of usage, and the user interface at various levels of abstraction in a declarative way. A model is a generalized representation of a portion of the world called the system. All of such models are typically stored in the description language of XML-based user interfaces. For intelligent user interfaces, XML has become a de facto
Knowledge bases store the information that the device has on both the program being performed and the sense of use. During the various stages of design, the information concerning the program is often collected. In our case, the meta-model used to store information is a slightly updated version of the usiXML1 definition language of the XML-based user interfaces. While description languages like XIML2 or UIML3 may be used for other user interfaces, too. The user interface information involves:
The
The
The
The
The
The user model contains certain user features important to the framework (preferences, skills, knowledge). Applying user-modeling techniques [38, 39] to the input data obtained by the sensors and the information already processed, this model is updated. For example, all the activities done by the client in the user interface are documented in the interaction log, so that the machine can use data mining or classification techniques to determine new user information to update the user model.
The platform model comprises the functionality (both hardware and software) of prospective system profiles where the program can be executed. By analyzing the input data from sensors, this model is also updated. For example, if the user increases the screen resolution, the visualization space available for viewing the contents is limited, and so the document structure, or even the contents themselves, is likely to change. Therefore, as the user modifies the screen resolution, the adjustment is identified by a device sensor so that the platform model can be changed accordingly.
The environment model contains the information about the physical world in which contact is performed. The potential amount of information collected from the surroundings would obviously be extremely large, and the developer must therefore determine which information is important because it has an effect on the application’s use. Once more, the data stored in this model is regularly updated by the incoming sensor data. Good relationship management means that all the information contained in the knowledge bases of the previously mentioned models is used efficiently and effectively.
The human-computer interaction utilizes the nature of intelligent user interfaces, leading to the problems that a user interface should still have about access and quality of use [40].
An outline of the design process is given in this section (Figure 4). Describing the situation-aware user interface, the design process encourages the layout of declarative abstract models [2].
Situation-aware Design Process for User Interface.
To export these models to the runtime, the aggregate of the models can be serialized. The corresponding UI can be created in the form of a prototype to check the responsiveness of the device in order to evaluate the outcome of these models. Considering the prototype, certain adjustments may be made to the templates in the modeling process to improve the appearance of the UI, for example, or how changes in the scenario can affect the UI.
Today, the development of intelligent user interfaces causes challenges equivalent to those encountered in Artificial Intelligence. It is well known that the optimal user interface is not the actual one in the area of human computer interaction. Currently, however, it is important to provide an intermediate between the wishes of the individual and the application of such intentions. It doesn’t matter how elegant a user interface is, it will still be there to provide the user with a mental workload.
The potential machine, according to A. van Dam or T. Furness [42], would be a great butler who knows my setting, my preferences and my character, and without needing clear orders, gets ahead of my needs in a subtle way. When the user communicates with this butler, movements, facial expressions [43, 44] and other means of human speech, such as designing drafts, will mostly talk about the interaction. A goal of Artificial Intelligence from its very beginning, 50 years ago, is to be able to provide objects that facilitate learning, development or connectivity peer to peer with an individual.
To actually come true, by applying computer vision techniques or speech recognition to perceive and understand natural language, certain agents may be able to translate gestures and emotions. The inference engine for such agents would be Artificial Intelligence and knowledge-based technologies. They would do so in a friendly way when these agents speak with the user, and potentially modulate their voice according to the mood of the user at a given point in time.
The complexities of this technology can be separated into three areas: input, inference and output and, more precisely, the analysis of human language expressions, the depiction and control of knowledge of the world and, ultimately, the perception of human beings as social beings.
In [45], a virtual companion-based interface was proposed by the authors to simplify the mobile interface for the elderly. This interface shows menus through a virtual agent as per the scenario and the request of users and animates information in a 3-dimensional layout. To collect input from users, the authors used speech recognition technologies from smartphones and wearable devices. To imagine suitable actions based on user feedback, virtual avatars were chosen. The authors predict that this mobile interface might be the future of the next user interface for smartphones.
In the treatment and healing process, IUI is often used in tasks of determining the functional status of an individual. The performance of functional state estimation is dependent on combined data from the accelerometer and the EEG [46].
Computer products today have the potential to provide information to us, to entertain us or to make our lives easier, but whether the user interface provided is limited or difficult to use, they may also slow down our job. A vision of how various approaches from different fields, including Artificial Intelligence, Software Engineering and Computer-Human Interaction, have been added over the years to help establish a successful user interaction experience, increasing the overall usability of the device, has been seen in this chapter. In [47] the authors explore the community’s evolving tacit viewpoint on intelligence characteristics in intelligent user interfaces and provide suggestions for expressing one’s own perception of intelligence more clearly.
User interfaces can be as normal in the future as listening to a human. We should also note that Human-Computer Interaction’s main aim is to reduce the mental distance between the user and his activities, dimming the interface until it becomes unseen. None the less, to get to the stage where we can provide users with virtual interfaces, there is always a long way to go. Computer-based automated interpretation of human sentiment and effect is generally predicted to play a significant role in future Intelligent User Interfaces, as it carries the potential of supplying immersive applications with emotional intelligence [48].
Another key of the study is that adding context to input in situation-aware systems results in automatic adjustment in awareness of the situation and action list, making the UI adapt to the actual operator’s unique needs. In addition, adaptation can only actually happen where the context and climate adjustment is sufficiently important to result in the transition between two possible user interface statuses. Adapting the interface to the actual scenario as defined in this prototype and providing reusable tasks with a reduced number of commands, clicks and choices decreases the operator’s cognitive burden and hence encourages interactions [49].
The artisanal fisheries of marine invertebrates in the archipelago of Madeira (NE Atlantic) target mainly gastropods and cephalopods. The main gastropod species harvested are the limpets
The artisanal harvest of gastropods in the archipelago of Madeira is a low-cost activity, usually carried out by the owner of the vessel accompanied by professional snorkelers. This activity is one of the most important small-scale fisheries in this region, due to the economic and social benefits it provides directly to the coastal communities and indirectly to the whole community. This fishery dates back to the fifteenth century when the Portuguese colonized the archipelago. The good accessibility to the rocky shores prompted the exploitation of marine shellfish resources along the coast. The harvest activity becomes progressively more intensive with the demographic increase of human settlement around the islands’ coasts and with the technological progresses that simplify the access to the coast at previously inaccessible areas [1, 2]. This long-term exploitation has changed the population dynamics, due to shifts on the abundance and/or size structure and density of the exploited marine gastropods over the years [3].
In the past, four species of the genus
Concerning topshell exploitation, two species of the genus
Both limpet consumption and topshell consumption in Madeira archipelago are part of the gastronomic cultural heritage of this region, appreciated by the local population and tourists alike, and have a high socioeconomic importance. Therefore, harvesting pressure on these resources is one of the greatest concerns. As such, a sustainable exploitation, based on suitable regulation considering the biological and ecological specificities of these species in their particular habitat, is crucial to promote the preservation of species and habitats at medium and long terms.
The aim of present work is to compile and characterize the harvest of limpets and topshells in the archipelago of Madeira, considering and discussing the evolution of the landings and economic values and describing the activity, fishing fleets, exploited species, and yields for a period of 27 years (1990–2017). Additionally, the impact of this activity on selected aspects of limpet and topshell population dynamics is analyzed and discussed.
The implemented management measures regulating the harvest of marine molluscs in the archipelago of Madeira are characterized in detail and their impact on the exploited stocks critically discussed through a comparative analysis of any relevant available data on these species from this region. Finally, the economic and social contextualization of this fishery is made in the overall fisheries sector in the region.
The archipelago of Madeira is located in the northeastern Atlantic Ocean and is included in the Macaronesian biogeographical region together with the Azores, Canary, and Cape Verde (Figure 1). The islands of these archipelagos are of volcanic origin, resulting from the activity of several geological hotspots and sharing the oceanic nature, the geographic location, and the climatic regime. However, with specific characteristics according to the proximity of the islands to the mainland regions [6].
Representation of the southern part of the Northeastern Atlantic showing the study area, the archipelago of Madeira, included in the Macaronesian biogeographical region.
The archipelago of Madeira comprises the islands of Madeira (741 km2 of area), Porto Santo (42 km2), Desertas (14 km2), and the Selvagens islands (3 km2). The island of Madeira is located approximately at 635 km from Morocco and at 900 km from the Portuguese mainland. The Selvagens islands are the southernmost territory of Portugal at 239 km from the island of Madeira and at 375 km from the coast of Morocco. This subtropical archipelago is influenced by the Azores anticyclone, the Gulf and the Canary currents, the continental anticyclonic center of Northwest Africa and Western Europe, and the frontal systems associated with the lower pressure center of the polar front [7].
The islands of Madeira and Desertas represent the most recent islands of the archipelago of Madeira with 4.6 and 3.6 million years, respectively. Porto Santo has an estimated age of 14.3 million years and the Selvages islands an estimated age between 24 and 29 million years [8, 9].
The population living in the archipelago of Madeira in 2017 was
Data on the landings (i.e., species, day, weight, and economic value) and on the artisanal fleet (i.e., length of the fishing vessel, tonnage, capacity, métier, fishery license) were obtained from the Regional Fisheries Department of Autonomous Region of Madeira (DRP-RAM) for both limpets and topshells.
Logbook data analyses were only available to characterize the limpet harvesting activity (i.e., harvesting area, typology of bottom, depth of harvesting, number of divers, number of snorkelers per vessel, and landing place and time), since it is mandatory to fill the logbooks according to the regulation of the limpet harvest in the archipelago of Madeira. For topshells these data are not available due to this activity not being regulated.
Landings data were compiled and analyzed covering the period from 1990 to 2017 and the logbook data from 2008 to 2017, concerning the period after the regulation of the harvesting of limpets that required the filling of all the harvesting information in logbooks.
The fisheries sector should protect fish resources and environment through an effective legal regulation and an appropriate compliance and enforcement to ensure the sustainable resource exploitation [10]. Based on this principle, the regulation of limpet harvesting in the archipelago of Madeira sets the basis for a sustainable and responsible exploitation of these resources.
The rules of governing the harvesting of limpets in Madeira were initially set by the necessity to establish proper measures to the regional specificities, with regard to the practice of underwater hunting. These measures were implemented through the article 6 of the Regional Government under the Regional Legislative Decree No 11/1995/M on 21 June 1995 and setting a maximum allowable catch of 3 kg/day per person for limpets. This was the first management action regarding the harvesting of gastropods in the archipelago of Madeira.
The legal regulation of the limpets’ harvesting method was decreed by the Legislative order No 1102-B/2000, 22 November 2000, which established the tools and instruments to be used in limpet harvesting.
The current limpets’ management in Madeira was based in technical measures implemented by the Regional Government under the Regional Legislative Decree No 11/2006/M, 18 April 2006, which establishes the legal regime for the harvesting of these gastropods in this region [3]. The management measures were implemented in 2006 based on the knowledge obtained from studies on the biology, population dynamics, and assessment of the stocks and intended to advise a precautionary approach capable of harmonizing the need to protect stocks with the preservation of the economic activities associated with their capture and gastronomic use [11]. For this purpose, regulators established several management measures for the traditional and commercial exploitation of the species
Additionally, the Legislative Orders No 80/2006 and No 81/2006, 17 June 2006, set the establishment of a closed season between November 1 and January 31 to avoid limpet harvest during the reproductive season and the rules concerning the harvesting card.
In 2009, based on continuous population monitoring, the closed season was changed to become effective between December 1 and February 28 (Legislative Order No 5/2009, 4 July 2009). In 2016, the closed season was extended through the Legislative Order No 40/2016, 17 February 2016, in result of the data obtained from the continuous monitoring of the stocks, in order to more efficiently provide protection to these heavily exploited species, now lasting from December 1 to March 31. The extension of the closed season is intended to result in biological benefits, allowing greater protection of spawning, larvae development, and settlement and to increase the success of annual recruitment and subsequent development of limpets. Additionally, the competent authorities implemented a reduction in the number of harvesting licenses aiming to diminishing the pressure on the resource [3, 12].
Since the implementation of limpet harvest regulation, the non-compliance of the imposed management measures is punishable with administrative offenses and penalties. The sanctions include monetary fines (between 49.88 € and 44,891.81 €), harvesting prohibition, and suspension of harvesting licenses. Nevertheless, poaching continues to occur during the closed season, without abiding the minimum catch size of 40 mm of shell length [3].
The regulation of limpets in the archipelago of Madeira allowed safeguarding the peak of reproduction, the immature specimens, and the catches of both
Currently, topshell harvest in the archipelago of Madeira is not regulated, with the exception of harvest ban on MPAs [2]. As such, the effort exerted and the shifts on the populations’ dynamics of the harvested populations, exploited for more than 500 years, are unknown. However, management measures based on recent studies [2] are in progress and shall enter into force during the year 2019, aiming to promote both profitable and sustainable harvest. The establishment of a maximum catch of 2 kg per day for noncommercial use and 20 kg per day for commercial use, the implementation of landing obligations and first sale at auction, the establishment of a minimum catch size of 15 mm shell length, and the establishment of a closed season between February and May are recommended [2].
Further European legislation through the European Community Council Regulation No 199/2008, 25 February 2008, prompted an increase in the knowledge regarding the fisheries sector in the European Union, including smaller sections such as limpet harvest, meeting the demands generated by the necessity to evolve toward a sustainable fisheries sector, with its management based on the fleet and fishing areas rather than based on fish stocks. As such, the collection of data and their availability by region will provide the basis for the better scientific advice.
Limpets and topshells are collected by hand, in the intertidal zone by the local population (traditional harvesting) and in the subtidal zone by snorkelers executing several dives per day (commercial harvesting), from 1 to 6 m deep (x ̅= 1.74 ± 1.31). The harvesting fleet operates preferentially on the northern coast of Madeira and Desertas Islands (Figure 2), the least accessible zones, while traditional harvesters collect limpets from all around the island preferably in areas with easy access and milder sea conditions.
Proportion of harvesting events of limpets per zone based on data from logbooks.
The harvest of limpets in the archipelago of Madeira is operated from April to November for limpets and all year round for topshells mostly by small vessels (<10 m). Between 1990 and 2017, the number of vessels operating on the harvesting of gastropods was reduced from 17 (1990) to 9 (2017) (Figure 3). The observed reduction in the number of vessels and licenses results from the implementation of regulation, which among other management measures included the gradual reduction in the number of fishing licenses and vessels in order to reduce the harvesting pressure on limpet stocks.
Number of fishing vessels operating in the harvesting of limpets from 1990 to 2017 in the archipelago of Madeira.
The majority of the fishing vessels have less than 10 m length (78%), and the remaining ranges between 10 and 12 m (11%) and between 12 and 18 m (11%). This artisanal fleet includes vessels of low tonnage (0.74–17.28 gross tonnage) and capacity between 11 and 136 KW, usually operating in nearby areas reachable in a short time.
Limpet harvest is deeply rooted in the local community and particularly on coastal fishing communities representing an additional revenue source for many families, thus contributing to the local economy. The number of snorkelers per fishing vessel, between 2008 and 2017, varied between two and eight depending on the vessel size (x ̅=4.9 ± 1.29). The number of professional harvesters registered per vessel and nonprofessional harvesters (15 kg/person/day) decreased over the study period following the management measures implemented (Figure 4).
Number of professional and nonprofessional harvesters registered in the archipelago of Madeira between 2016 and 2018.
A remarkable proportion of the Madeiran fishing fleet focuses solely on the harvesting of gastropods; nevertheless due to the implementation of a closed season, some fishing fleets operate with two or three métiers. In 2017, 56% of the fishing fleet operated exclusively in the harvesting of gastropods; 33% operated with 3 métiers and 11% with 2 métiers (Figure 5). The complementary métiers were essentially directed to the capture of tuna fish and demersal fish.
Proportion of métiers operated by the fishing vessels involved in the harvesting of gastropods in the archipelago of Madeira.
In the archipelago of Madeira, limpets are mostly harvested by scuba diving in a mixed exploitation of
The commercial landings in weight of limpets harvest varied from
Representation of landings (tonnes) and economic value (1000 euros) of limpets from 1990 to 2017 in the archipelago of Madeira.
The limpets landed in Madeira are for internal consumption and, to a minor extent, for exportation, mainly to the archipelago of Azores. However, data on the exportations of limpets are not available and as such are not possible to determine accurately.
The average annual value of limpets per kg landed in the archipelago of Madeira fluctuated considerably, from 1990 to 2017, increasing from 1.80 € in 1990 to 3.65 € in 2017 (x ̅=3.33 ± 1.25 €). For this period the average annual price varied from 1.21 € in 1990 to 5.90 € in 2008 (Figure 7). Since 2008, the value per kg decreased due to the increase in landings and the demand for this resource. Even so, the value per kg is still very attractive for the professionals involved in this activity.
Average annual price of the limpets landed in the archipelago of Madeira from 1990 to 2017.
The harvesting effort, represented by the number of days employed in the harvest of limpets, decreased from 1448 days in 2008 to 655 days in 2017. However, in general the reduction in fishing effort contrary to what would be expected led to an increase in the landings (
Landings and harvesting effort from 2008 to 2017 in the harvesting of limpets in the archipelago of Madeira.
The highest proportion of landings of limpets, for the considered time period, occurred from May to August, corresponding to the months with better sea conditions in the archipelago of Madeira (Figure 9). The comparison between monthly landings before and after the implementation of the closed season showed that the highest proportion of landings remained identical between the two periods, except for the months of the closed season, when limpet harvesting is not allowed.
Proportion of landings of limpets per month before (1990–2007) and after (2008–2017) the implementation of management measures in the archipelago of Madeira.
In the archipelago of Madeira, landings of limpet commercially harvested, between 1990 and 2017, occurred in 10 ports, namely, Funchal, Câmara de Lobos, Calheta, Madalena do Mar, Paúl do Mar, Porto Moniz, Santa Cruz, Machico, Caniçal, and Porto Santo. The total landings per port in tonnes are represented in Figure 10. During this period, Porto Moniz, Funchal, Caniçal, and Paúl do Mar were the most important ports representing approximately 96% of the limpets landed in 1990 and 100% of the limpets landed in 2017. Porto Moniz showed the highest annual limpet landings with 1.9 tonnes in 1990 and 76 tonnes in 2017, representing approximately 69% of the total landings of limpets in 2017 (Figure 11). Six fishing vessels landed
Total landings of limpets per port between 1990 and 2017.
Landings of limpets per year considering the landing port.
The commercial landings of limpets (in weight) in the archipelago of Madeira increased from 12% in 1990 to 96% of the total of molluscs landed in this region (Figure 12). Since 1998, limpets represent >90% of the landed molluscs in weight, increasing in importance over the years.
Landings of limpets and the landings of the total molluscs per year, between 1990 and 2017 in the archipelago of Madeira.
The economic importance of limpets in the fisheries sector of the archipelago of Madeira gradually increased over the years. In 1990, limpets represented approximately 26% of the total economic value landed for molluscs and in 2017 approximately 96%. Since 1991, limpets represent the majority of the landed value for molluscs. From 1998 to 2017, this resource represents over 90% of the landings of molluscs (Figure 13).
Economic value of the landings of limpets and the economic value of the landings of the other molluscs per year, between 1990 and 2017 in the archipelago of Madeira.
The traditional harvesting of limpets carried out by the local populations is not represented in the landings since current harvesting regulation does not require first auction sale for this activity (<3 kg/day/person), thus making it difficult to quantify the real impact of the traditional harvest on the exploited populations. Also, illegal harvest is not considered on the total of landings. Nonetheless, it is known that commercial harvest occurs preferentially on certain locations (north coast of Madeira Island and around the Desertas), and, for these regions at least there is a better understanding of the harvesting effort on the exploited stocks.
The topshell (
Landings and economic value of topshells from 1990 to 2017 in the archipelago of Madeira.
Specific stock assessments for limpets in the archipelago of Madeira begun in the mid-2000s and were the basis for regulation of shellfish harvest in the region [11]. Nevertheless, due to the increasing interest in these molluscs, preliminary monitoring of limpet populations began in 1996. More recently, studies on the biology and stock assessment of
The stocks of
Presently, some concerns persist regarding the management of the commercial exploitation of these two species in the region, namely, the lack of knowledge on the genetic connectivity between populations. In this sense, studies in this field are ongoing to establish proper conservation strategies considering connectivity or isolation of the populations. Another important concern relates to illegal poaching in the closed season and in MPAs and new conservation policies raising public awareness using innovative approaches involving not only decisionmakers but also the local communities which will be pivotal for the conservation of these species [12].
The first approach to assess the status of the stock of the topshell
The implementation of limpet harvest management measures in the archipelago of Madeira was of paramount importance due to the life history traits of these species allied to their economic importance that results in a high harvesting pressure on these resources.
The continuous monitoring of the limpet populations over time allowed the regulators to readjust harvesting regulation in Madeira, namely, the closed season period that initially lasted from November to January and presently ranges from December to March, to protect more effectively the breeding period of limpet species. This continuous monitoring clearly maximizes the returns that can be achieved through the regulation of this activity; since the responses of exploited stocks to harvest are continually changing, regulation has to adapt to these changes in order to promote its sustainability. The reduction of the number of harvesting licenses, the prohibition to capture immature individuals (<40 mm shell length), and the catch limits have also contributed to the increase of the mean size of the specimens, to the recovery of the size composition and to the increase of the abundance of the limpets’ populations, in the archipelago of Madeira [3].
Conservation measures prompted an overall improvement of the exploited stocks on both exploited limpet species in Madeira. Comparative studies on the effectiveness of the implemented management measures demonstrated that the stocks of
The implemented management measures and the current levels of enforcement in the archipelago of Madeira showed positive results contrarily to those in the archipelago of Azores and the Canaries where management and enforcement were insufficient to protect the exploited limpet populations [15, 16].
The management measures led to an increase of 14% in proportion of reproductive individuals and to an increase in the size and age of first maturity for both species. A shift from a biased sex ratio before harvesting regulation to a balanced sex ratio after regulation occurred for
Marine protected areas also contributed to the protection of limpet populations in the archipelago of Madeira. The increase of size-at-first maturity, shell size, balanced size composition, and capture per unit effort (CPUE) is evident in MPAs when compared to exploited populations. Also in the oldest and well-enforced MPAs, a high representation of large adults and more balanced populations for both limpet species (R.S., per. Obs.) was found. In fact, MPAs play a pivotal role in the recovery of the exploited stocks of limpets in the archipelago of Madeira, considering their potential to promote replenishment and recruitment in nearby coastal areas where limpets are or have been heavily exploited. However, further studies are required to confirm this possible positive effect of MPAs on limpet stocks.
The harvesting of limpets in the archipelago of Madeira is protected by legislation that provides the basis for a sustainable exploitation. However, it is still very common for violations to the current management policies and regulations which are punishable with the application of penalties when detected by the local authorities to occur. The two major weaknesses in this regard are the lack of compliance by the fishermen, which is mostly due to the lack of knowledge about the importance of the implemented management measures, and the poor enforcement by the regional authorities. A greater effort in the enforcement of regulations is required to ensure compliance of the fishing communities and an increase of the surveillance by the authorities to discourage illegal harvesting of these molluscs. Concerning topshells it is crucial to establish management measures on the harvesting of this resource to promote a sustainable exploitation in a medium and long term.
The ecological role that these key resources play in the coastal ecosystem and the importance of their survival not only from a conservational perspective but also economical needs to clearly transmitted to the fishermen and the general public, stakeholders, and authorities. This can be achieved through a proximity approach promoting training and involvement of all interested parties in the management and protection of these species. Promoting the awareness and advice to consumers in order to reduce illegal harvesting. Also, by instilling entrepreneurial spirit in fishermen by complementing their fishing activity with tourism through vessel trips and dives, adding value to these resources and increasing the fishermen income.
The implementation of obligatory species-specific landings for limpets is urgent to more accurately quantify the landings of each species and monitor the exploited stocks, since they are landed together as a mixed exploitation.
The encouragement of aquaculture investments and post-harvest facilities will reduce fishing pressure on exploited gastropods in the archipelago of Madeira and open the possibility of stock replenishment by reintroduction of cultured individuals to their natural habitat. This would also positively contribute to the socioeconomic development of the region, not only through production but also through job creation.
The authors are grateful to the Fisheries Research Service (DSI) of the Regional Directorate of Fisheries of the Autonomous Region of Madeira for providing the information used in this work. The first author (RS) was supported by a grant from ARDITI OOM/2016/010 (M1420-01-0145-FEDER-000001-Observatório Oceânico da Madeira-OOM) and the second author (JV) by a grant from FCT (SFRH/BSAB/143056/2018). The present study has been also supported by the UE European Regional Development Fund in the framework of the Projects MARISCOMAC (MAC/2.3d/097), MACAROFOOD (MAC/2.3d/015), the Regional Government of Madeira, and FCT through the strategic project UID/MAR/04292/2019 granted to MARE.
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\\n\\n1.2. REMOVALS AND CANCELLATIONS
\\n\\n2. STATEMENTS OF CONCERN
\\n\\nA Statement of Concern detailing alleged misconduct will be issued by the Academic Editor or publisher following a 3rd party report of scientific misconduct when:
\\n\\nIntechOpen believes that the number of occasions on which a Statement of Concern is issued will be very few in number. In all cases when such a decision has been taken by the Academic Editor the decision will be reviewed by another editor to whom the author can make representations.
\\n\\n3. CORRECTIONS
\\n\\nA Correction will be issued by the Academic Editor when:
\\n\\n3.1. ERRATUM
\\n\\nAn Erratum will be issued by the Academic Editor when it is determined that a mistake in a Chapter originates from the production process handled by the publisher.
\\n\\nA published Erratum will adhere to the Retraction Notice publishing guidelines outlined above.
\\n\\n3.2. CORRIGENDUM
\\n\\nA Corrigendum will be issued by the Academic Editor when it is determined that a mistake in a Chapter is a result of an Author’s miscalculation or oversight. A published Corrigendum will adhere to the Retraction Notice publishing guidelines outlined above.
\\n\\n4. FINAL REMARKS
\\n\\nIntechOpen wishes to emphasize that the final decision on whether a Retraction, Statement of Concern, or a Correction will be issued rests with the Academic Editor. The publisher is obliged to act upon any reports of scientific misconduct in its publications and to make a reasonable effort to facilitate any subsequent investigation of such claims.
\\n\\nIn the case of Retraction or removal of the Work, the publisher will be under no obligation to refund the APC.
\\n\\nThe general principles set out above apply to Retractions and Corrections issued in all IntechOpen publications.
\\n\\nAny suggestions or comments on this Policy are welcome and may be sent to permissions@intechopen.com.
\\n\\nPolicy last updated: 2017-09-11
\\n"}]'},components:[{type:"htmlEditorComponent",content:'IntechOpen’s Retraction and Correction Policy has been developed in accordance with the Committee on Publication Ethics (COPE) publication guidelines relating to scientific misconduct and research ethics:
\n\n1. RETRACTIONS
\n\nA Retraction of a Chapter will be issued by the Academic Editor, either following an Author’s request to do so or when there is a 3rd party report of scientific misconduct. Upon receipt of a report by a 3rd party, the Academic Editor will investigate any allegations of scientific misconduct, working in cooperation with the Author(s) and their institution(s).
\n\nA formal Retraction will be issued when there is clear and conclusive evidence of any of the following:
\n\nPublishing of a Retraction Notice will adhere to the following guidelines:
\n\n1.2. REMOVALS AND CANCELLATIONS
\n\n2. STATEMENTS OF CONCERN
\n\nA Statement of Concern detailing alleged misconduct will be issued by the Academic Editor or publisher following a 3rd party report of scientific misconduct when:
\n\nIntechOpen believes that the number of occasions on which a Statement of Concern is issued will be very few in number. In all cases when such a decision has been taken by the Academic Editor the decision will be reviewed by another editor to whom the author can make representations.
\n\n3. CORRECTIONS
\n\nA Correction will be issued by the Academic Editor when:
\n\n3.1. ERRATUM
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\n\nA published Erratum will adhere to the Retraction Notice publishing guidelines outlined above.
\n\n3.2. CORRIGENDUM
\n\nA Corrigendum will be issued by the Academic Editor when it is determined that a mistake in a Chapter is a result of an Author’s miscalculation or oversight. A published Corrigendum will adhere to the Retraction Notice publishing guidelines outlined above.
\n\n4. FINAL REMARKS
\n\nIntechOpen wishes to emphasize that the final decision on whether a Retraction, Statement of Concern, or a Correction will be issued rests with the Academic Editor. The publisher is obliged to act upon any reports of scientific misconduct in its publications and to make a reasonable effort to facilitate any subsequent investigation of such claims.
\n\nIn the case of Retraction or removal of the Work, the publisher will be under no obligation to refund the APC.
\n\nThe general principles set out above apply to Retractions and Corrections issued in all IntechOpen publications.
\n\nAny suggestions or comments on this Policy are welcome and may be sent to permissions@intechopen.com.
\n\nPolicy last updated: 2017-09-11
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Analysis of the results shows the success of the developed system in the competition arena of two of the largest outdoor robotics challenges. Throughout the chapter, we highlight the evolution of the robotic system based on the experience gained in the ERL competition. We conclude the chapter with key findings and additional improvement ideas to advance the state of the art in search and rescue applications of heterogeneous robotic teams.",book:{id:"10821",title:"Automation and Control - Theories and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/10821.jpg"},signatures:"Barbara Arbanas, Frano Petric, Ana Batinović, Marsela Polić, Ivo Vatavuk, Lovro Marković, Marko Car, Ivan Hrabar, Antun Ivanović and Stjepan Bogdan"}],onlineFirstChaptersTotal:4},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:0,limit:8,total:null},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:87,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:98,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:27,numberOfPublishedChapters:287,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:9,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:139,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:129,numberOfOpenTopics:0,numberOfUpcomingTopics:2,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!1},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:106,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:10,numberOfPublishedChapters:103,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:12,numberOfOpenTopics:2,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:0,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!1},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:9,numberOfOpenTopics:4,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. 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Biochemistry examines macromolecules - proteins, nucleic acids, carbohydrates, and lipids – and their building blocks, structures, functions, and interactions. Much of biochemistry is devoted to enzymes, proteins that catalyze chemical reactions, enzyme structures, mechanisms of action and their roles within cells. Biochemistry also studies small signaling molecules, coenzymes, inhibitors, vitamins, and hormones, which play roles in life processes. Biochemical experimentation, besides coopting classical chemistry methods, e.g., chromatography, adopted new techniques, e.g., X-ray diffraction, electron microscopy, NMR, radioisotopes, and developed sophisticated microbial genetic tools, e.g., auxotroph mutants and their revertants, fermentation, etc. More recently, biochemistry embraced the ‘big data’ omics systems. Initial biochemical studies have been exclusively analytic: dissecting, purifying, and examining individual components of a biological system; in the apt words of Efraim Racker (1913 –1991), “Don’t waste clean thinking on dirty enzymes.” Today, however, biochemistry is becoming more agglomerative and comprehensive, setting out to integrate and describe entirely particular biological systems. The ‘big data’ metabolomics can define the complement of small molecules, e.g., in a soil or biofilm sample; proteomics can distinguish all the comprising proteins, e.g., serum; metagenomics can identify all the genes in a complex environment, e.g., the bovine rumen. 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Dr. Blumenberg’s research is focused on the epidermis, expression of keratin genes, transcription profiling, keratinocyte differentiation, inflammatory diseases and cancers, and most recently the effects of the microbiome on the skin. 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He worked on the structure-function relationships of glycoconjugates and his main project was the investigations on the biological roles of the de-N-glycosylation enzymes (Endo-N-acetyl-β-D-glucosaminidase and peptide-N4-(N-acetyl-β-glucosaminyl) asparagine amidase). From 2002 he contributes to the understanding of the Blood-brain barrier functioning using proteomics approaches. He has published more than 70 papers. 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Since 1983, he has been a faculty member of the RO Perelman Department of Dermatology, NYU School of Medicine, where he is codirector of a training grant in cutaneous biology. Dr. Blumenberg’s research is focused on the epidermis, expression of keratin genes, transcription profiling, keratinocyte differentiation, inflammatory diseases and cancers, and most recently the effects of the microbiome on the skin. He has published more than 100 peer-reviewed research articles and graduated numerous Ph.D. and postdoctoral students.",institutionString:null,institution:{name:"New York University Langone Medical Center",institutionURL:null,country:{name:"United States of America"}}}]},{type:"book",id:"7978",title:"Vitamin A",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7978.jpg",slug:"vitamin-a",publishedDate:"May 15th 2019",editedByType:"Edited by",bookSignature:"Leila Queiroz Zepka, Veridiana Vera de Rosso and Eduardo Jacob-Lopes",hash:"dad04a658ab9e3d851d23705980a688b",volumeInSeries:3,fullTitle:"Vitamin A",editors:[{id:"261969",title:"Dr.",name:"Leila",middleName:null,surname:"Queiroz Zepka",slug:"leila-queiroz-zepka",fullName:"Leila Queiroz Zepka",profilePictureURL:"https://mts.intechopen.com/storage/users/261969/images/system/261969.png",biography:"Prof. Dr. Leila Queiroz Zepka is currently an associate professor in the Department of Food Technology and Science, Federal University of Santa Maria, Brazil. 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