Simulation parameters.
\r\n\tThis book will consist of chapters that are an elegant mix of reviews and current developments on the subject that will be useful both to an expert on the subject as well as a newcomer to this area of research.
",isbn:"978-1-83969-076-1",printIsbn:"978-1-83969-075-4",pdfIsbn:"978-1-83969-092-1",doi:null,price:0,priceEur:0,priceUsd:0,slug:null,numberOfPages:0,isOpenForSubmission:!0,isSalesforceBook:!1,hash:"8a2fd9bbbbae283bf115881d9d5cc47a",bookSignature:"Dr. Ashim Kumar Dutta",publishedDate:null,coverURL:"https://cdn.intechopen.com/books/images_new/11857.jpg",keywords:"Frenkel Excitons, Wannier-Mott Excitons, Low Dimensional Solids, Molecular Crystals and Aggregates, Exciton Diffusion and Hopping, Exciton–Exciton Annihilation, Dynamics, Scaling Laws, Photoluminescence, Exciton Lifetime, Energy Harvesting, Semiconductors",numberOfDownloads:null,numberOfWosCitations:0,numberOfCrossrefCitations:null,numberOfDimensionsCitations:null,numberOfTotalCitations:null,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"April 19th 2022",dateEndSecondStepPublish:"May 17th 2022",dateEndThirdStepPublish:"July 16th 2022",dateEndFourthStepPublish:"October 4th 2022",dateEndFifthStepPublish:"December 3rd 2022",remainingDaysToSecondStep:"7 days",secondStepPassed:!0,currentStepOfPublishingProcess:3,editedByType:null,kuFlag:!1,biosketch:"Dr. Ashim Kumar Dutta received his Ph.D. in physical chemistry from the Indian Association for the Cultivation of Science (IACS). He has worked on various international post-doctoral fellowships in Japan, Canada, and USA. Dr. Dutta has worked as head of research and product development in several companies, and presently works as vice-president for India Glycols Limited. He has authored/co-authored 36 articles in international journals and 21 patents.",coeditorOneBiosketch:null,coeditorTwoBiosketch:null,coeditorThreeBiosketch:null,coeditorFourBiosketch:null,coeditorFiveBiosketch:null,editors:[{id:"277477",title:"Dr.",name:"Ashim",middleName:"Kumar",surname:"Dutta",slug:"ashim-dutta",fullName:"Ashim Dutta",profilePictureURL:"https://mts.intechopen.com/storage/users/277477/images/system/277477.jpg",biography:"Dr. Ashim Kumar Dutta presently works as the vice president (R&D) with India Glycols Limited, one of the largest manufacturers of Green Surfactants in South East Asia. Earlier, he had worked with Unilever as a senior researcher and product development manager in their Home and Personal Care Category, with United Phosphorus Limited and Indofil as their global head for agrochemical formulations. He has authored/co-authored 36 articles in international journals and 19 patents. He received his Ph.D in physical chemistry from Indian Association for the Cultivation of Science (IACS) – a premiere research institute in India in 1993. Dr. Dutta has worked on various international post-doctoral fellowships in Japan, Canada and USA. His research interests include supramolecular assemblies, ultrathin nanostructured films, nanoparticles, novel surfactants, surfactant-polymer interactions, bio-membranes and spectroscopy of Langmuir-Blodgett films, tribology and rheology of complex systems.",institutionString:"India Glycols Limited",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"1",totalChapterViews:"0",totalEditedBooks:"1",institution:null}],coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"20",title:"Physics",slug:"physics"}],chapters:null,productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},personalPublishingAssistant:{id:"440204",firstName:"Ana",lastName:"Cink",middleName:null,title:"Ms.",imageUrl:"https://mts.intechopen.com/storage/users/440204/images/20006_n.jpg",email:"ana.c@intechopen.com",biography:"As an Author Service Manager my responsibilities include monitoring and facilitating all publishing activities for authors and editors. From chapter submission and review, to approval and revision, copyediting and design, until final publication, I work closely with authors and editors to ensure a simple and easy publishing process. I maintain constant and effective communication with authors, editors and reviewers, which allows for a level of personal support that enables contributors to fully commit and concentrate on the chapters they are writing, editing, or reviewing. I assist authors in the preparation of their full chapter submissions and track important deadlines and ensure they are met. I help to coordinate internal processes such as linguistic review, and monitor the technical aspects of the process. As an ASM I am also involved in the acquisition of editors. 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As can be seen in the modern multi-processor system-on-chips and many core systems [1, 2, 3], this makes computing hardware devices equip with hundreds or thousands of processor cores for providing high computation power by parallel processing on a chip. For the implementation of such highly-integrated parallel systems, Network-on-Chip (NoC) has emerged as a promising paradigm. In NoCs, each node (i.e. a processor core with a router) is connected by an on-chip network and communication among them are done by transferring packets on the network. Using global interconnection structure reduces the difficulty of wiring design and latency of signal transmission and offers high scalability, in comparison with point-to-point signal wires or shared busses [4].
One of the most important and fundamental issues that must be addressed for NoCs is fault-tolerant routing. Definitely, routing of packets plays a key role in parallel systems because it has significant impact on the overall system performance. Meanwhile, the occurrence of faults during system fabrication and run time is inevitable, and it is almost impossible to completely remove their adverse effects from the systems even if some redundancy is incorporated. A single faulty node disrupts packet routing between many pairs of nodes, resulting in the failure of the entire system. Besides, a deadlock (i.e. circular waiting of packets) will occur if an adopted routing algorithm is imperfect. Once the deadlock occurs, packets can never proceed to the destinations, and thus resulting in the malfunction of the entire system. Therefore, designing an efficient fault-tolerant routing algorithm with the property of deadlock-freeness is crucial for realizing dependable NoC systems with high communication performance.
So far, extensive research has been devoted to fault-tolerant routing not only for NoCs but for traditional parallel computers. Although there exist several basic approaches, as we reviewed in Section 2, the common idea of the fault-tolerant routing remains unchanged from the earliest, and it has been undoubtedly to detour faulty nodes. This is quite natural because the purpose of the fault-tolerant routing is to route packets from source to destination nodes without entering faulty parts. Meanwhile, it is also obvious that detouring faulty nodes increases the communication latency as the packet is misrouted apart from the minimal path to the destination. One may consider that the increase in the communication latency is very little. This is true if packets are routed without interfered by other packets. However, it can be substantial increase under the situation where a number of packets are routed simultaneously and thus frequently blocked by others.
In this chapter, we introduce a novel approach for the design of fault-tolerant routing algorithms. In contrast to the common idea of detouring faulty nodes, our approach allows passing through them with the slight modification of NoC architecture. We provide a general methodology for designing a fault-tolerant routing algorithm with the passage of faulty nodes. As a design example, we describe an XY-based routing algorithm with the passage function. By computer simulations, we reveal the communication performance of the algorithm under the condition of with and without Virtual Channels (VCs), in comparison with well-known region-based routing algorithms.
The rest of this chapter is organized as follows: Section 2 presents the architecture of NoC, the basis of packet routing, and the related works of fault-tolerant routing algorithms. Section 3 presents the basic idea of the proposed approach and XY-based fault-tolerant routing algorithm, inclusive of the proof of the deadlock-freeness. Section 4 presents the results of the performance evaluation. Finally, Section 5 concludes the chapter with some possible direction of future research.
Target NoC topology in this chapter is a popular 2D mesh which has nodes of
Architecture of 2D mesh NoC.
Figure 2 shows the block diagram of the router. In the typical wormhole routing adopted in NoCs, a packet is divided into a sequence of fixed-size units of data, called flits, and transferred by routers one after another. Each router consists of five input/output units, five routing circuits, a VCs allocator, a crossbar switch, and a switch allocator. When a head flit (i.e. a flit having routing information) is transferred to a router and stored into a buffer in the input unit, the following processes are applied.
An output port to which the flit is forwarded is determined by the routing circuit.
A VC (i.e. buffer) to be used is determined by the VC allocator.
The crossbar switch is set up by the switch allocator to connect the input unit and the output unit associated with the determined output port.
The flit is moved from the input to the output units.
Finally, the flit is forwarded to the corresponding input unit of the next router.
Architecture of router.
The incoming head flit moves to the next router at the fifth cycle if there are no contentions, and the subsequent flits follow it in a pipeline fashion. This is a standard five-cycle router [5]. If no VC is used in an adopted routing algorithm, the router is reduced to a four-cycle router, as the second process (i.e. VC allocation) is omitted.
In routing packets in accordance with a routing algorithm, the algorithm must care about the occurrence of deadlocks. Deadlock is a situation where packets wait on one another to release the buffers. Figure 3 shows an example of a deadlock. In this example, a packet A is routed to the node
Example of a deadlock.
There have been two approaches to preventing deadlocks; approaches with and without VCs. In the approach with VCs, the original network is multiplexed into several virtual networks by VCs. For example, in Figure 3, if packets A and C are supposed to be routed on a virtual network with a VC and packets B and D are on a different virtual network with other VC, then the circular waiting is decomposed and packets get to proceed to the destinations. In the approach without VCs, a routing algorithm is carefully designed so that deadlocks never occur in the original physical network. For example, in Figure 3, if packets A and C are routed via
Fault-tolerant routing has been the subject of extensive research not only for NoCs but for traditional parallel computers over the past few decades. Most of the existing fault-tolerant routing algorithms for 2D mesh networks fall into the following three categories: (1) those employ a routing table, (2) those relax the constraints of guaranteed delivery or deadlock-freeness, and (3) those define some form of fault information on routers and detour paths.
In the first category, a routing table is employed in each router to route packets to the destinations. Routing tables contain routing information such as next hops for destinations, status of the network, and/or fault information. Hsin et al. [6] proposed an algorithm which employs ant colony optimization for traffic balancing. Liu et al. [7] proposed an algorithm which introduces coarse and fine-grained look-ahead schemes to obtain the information of other routers within the range of four hops. This algorithm requires two VCs for each input/output port to route packets. Zhao et al. [8] proposed an algorithm to provide minimal paths using the information of whole network. In general, those algorithms offer flexible route selection; however, they require a large amount of circuits to implement a routing table and complex calculation mechanism to create/update the table in all routers.
In the second category, constraints of guaranteed delivery or deadlock-freeness is relaxed to ease the design of routing algorithms. Janfaza et al. [9] proposed an adaptive routing algorithm which employs timeout and packet reinjection. Information of intermediate nodes is recorded in each packet and two VCs are used to route packets. Sinha et al. [10] proposed an algorithm based on the common XY and YX routing. This algorithm allows U-turn using several VCs. Wang et al. [11] proposed an algorithm which relaxes transmission accuracy for the applications that allow lossy communication. This algorithm discards conflicting approximate flits without retransmission and recovers them after packet transmission. Those algorithms are imperfect in that 100% packet reachability or deadlock-freeness are not guaranteed by the routing algorithms. Retransmission of packets generally results in a high communication latency.
In the third category, some form of fault information is defined for routers to detour faulty parts. Usually, clusters of faulty nodes, called fault blocks, are defined in the networks with the detour paths. Chen et al. [12], Holsmark et al. [13], Fu et al. [14], and Fukushima et al. [15] proposed routing algorithms which generate rectangular fault blocks and detour them without using VCs. Wu [16] and Chalasani et al. [17] proposed routing algorithms which can deal with convex and nonconvex fault blocks, respectively. In [17], four VCs are used to choose shorter detour paths. Those algorithms called region-based algorithms provide simple but strict routing rules to guarantee the deadlock-freeness and 100% packet reachability, and thus, they can be implemented as a small circuit in the routing circuit of each router. They are practical and suitable for NoCs. However, one drawback is that fault blocks may include several non-faulty nodes, which are to be deactivated (i.e. unused nodes); therefore, the number of unused nodes and the length of detour paths are prone to increase if there exist a number of faulty nodes in the network.
Although extensive research has been devoted to designing fault-tolerant routing algorithms inclusive of the above ones, the common idea remains unchanged from the earliest, and it has been undoubtedly to detour faulty nodes. If a packet must detour a faulty node
Motivated by the problem presented in the previous section, we introduce a novel approach based on the opposite idea of the common approach; our approach allows packets to pass through the faulty nodes with slight modification of NoC architecture (originally proposed in [18]). Basic idea behind this approach is to reduce communication latency by saving detouring as much as possible.
Figure 4 shows the modified NoC architecture for supporting the proposed approach. Four electrical switches, bypass links, buffers to store one flit are added around each router. Each switch has two states, either normal or passage, as shown in this figure. In the state of passage, packets from the neighbor node are input to the bypass link not to the node. The switch states can be determined easily, once the node is tested and judged as faulty or not. In other words, they are determined so that the node becomes passage state if it is faulty or remains normal state otherwise. It is worth to note that buffers can be removed if packets are transmitted between routers in an asynchronous way.
Modified NoC architecture.
Here, we provide a design methodology for fault-tolerant routing algorithms based on the passage of faulty nodes.
First, we clarify the fault model. A common assumption is made for faults [6, 12, 13, 14, 15, 16, 18, 19]; that is, permanent faults are considered to be associated only with nodes. In practice, the probabilities of links, switches, and buffers being faulty are not zero, though they will be substantially small because of the simplicity of their circuits [19]. For the faults on those circuits, one can employ some popular redundancy technique such as duplication and triplication if necessary.
Below is the general methodology for designing fault-tolerant routing algorithms with the passage function.
As a design example, we introduce a new fault-tolerant routing algorithm based on the popular dimension order routing (i.e. XY routing for 2D meshes) [18]. In the following, we explain the details of each step in the design methodology.
In Step 1, we choose XY routing as a base routing algorithm. In XY routing, packets first proceed along x-direction until they reach the nodes having the same x-coordinates as the destinations, then proceed to the destinations along y-direction without changing the x-coordinates.
In Step 2, we must consider the case where passage must be restricted. For example, suppose that a packet moves from node
Then, we need to consider the case where a faulty node is on the south boundary of the network. In this case, packets cannot detour it through the south side, as they face the south boundary. To cope with this, we give the following definitions.
The process in Definition 2 is repeated until no SF nodes are generated. For SF nodes, we give a new routing rule such that packets must detour them through the north side.
In Step 3, we check the deadlock-freeness of the resultant routing algorithm
Example of a possible deadlock.
To cope with the deadlock, we give the following definitions.
For the newly generated SF nodes in Definition 3, the processes in Definitions 2 and 3 are repeated until no SF nodes are generated.
Figure 6 illustrates examples of the SF area. In the case of Figure 6 (a), faulty node (
SF area for xy-based routing algorithm.
By the above definitions, the deadlock in Figure 5 can be solved. By Definition 3, two faulty nodes in Figure 5 are changed to SF nodes and the SF area is defined as shown in Figure 7. Then, two packets detour the SF nodes, not faulty nodes, through the north side and get to proceed to the destinations as shown in the figure.
Routing example without deadlocks.
Figure 8 describes the finally obtained proposed routing algorithm. In this figure, C and D represent a current and a destination node, respectively. The proposed routing algorithm allows packets to pass through faulty and SF nodes in the movement of x-directions only if C and D are on the same row (i.e. lines 8 and 18 in Figure 8), while it always allows passage in the movement of y-directions.
A pseudo-code of the proposed routing algorithm.
Next, we prove the deadlock-freeness of the proposed algorithm described in Figure 8. First, we define turns of packets.
Possible eight turns of packets.
For the clockwise direction, we show that an SW turn is never aligned with an NE turn. The SW turn occurs in a non-SF area; however, the NE turn never occurs in the area because it only occurs in an SF area. Conversely, the NE turn occurs in an SF area; however, the SW turn only occurs in a non-SF area. From the above, circular waiting never occurs in the clockwise direction.
For the counter-clockwise direction, we omit the proof because it is symmetrical to the proof for the clockwise direction.
Thus, the proposed routing algorithm is proved to be deadlock-free.□
To investigate the effect of the proposed approach, we have conducted computer simulations with a cycle-accurate custom simulator developed in C. This simulator accurately simulates the behavior of flits in all routers in a 2D mesh NoC. As explained in Section 2, if there are no contentions, each flit takes five (or four) cycles to move to the next node when VCs are used (or not used) in the adopted routing algorithm. Note that, as flits are transmitted in a pipeline fashion, a subsequent flit moves to the next node one cycle after the movement of the precedent flit if buffer space is available in the input unit of the router. It also takes one cycle to pass through a faulty node, as a buffer is placed on the bypass link.
Following three methods are evaluated in the simulations with the parameters listed in Table 1.
Fukushima’s method [15]: packets detour
Chalasani’s method [17]: packets detour
Our method [18]: packets can
Parameter | Value | Unit |
---|---|---|
Network size | 10 | Nodes |
Fault rate ( | 2, 4, 6, 8, 10 | % |
Packet length | 16 | Flits |
Packet generation rate ( | 0.05 | Packets/cycle/network |
Input (Output) buffer depth | 8 (1) | Flits |
Simulation (Stabilization) cycle | 50,000 (5000) | Cycles |
Simulation parameters.
The number of VCs required for each algorithm is different, and VCs can also be employed in the algorithms which require no VCs for the purpose of congestion avoidance. We use the notation of
In the simulations, faulty nodes are generated randomly according to the fault rate
To make a quantitative evaluation of average latency, we define maximum latency reduction rate of an algorithm
where
where
Figures 10–14 show the average latency as a function of packet generation rate
Average latency for
Average latency for
Average latency for
Average latency for
Average latency for
Figure 15 shows the average node utilization rate.
Average node utilization rate vs. fault rate.
For the results shown in Figures 10–14, we make performance comparison of the routing algorithms in the following three conditions.
The average latency of the original routing algorithms is compared numerically (i.e. comparison of
−94 (0.55) | −93 (0.45) | −92 (0.40) | −91 (0.35) | −89 (0.30) | ||
82 (0.75) | 82 (0.60) | 79 (0.50) | 81 (0.45) | 83 (0.40) |
Maximum latency reduction rate
Next, the average latency of the three algorithms is compared by increasing the number of VCs twofold, threefold, and fourfold from the original (i.e. comparison of
With twofold VCs, the average latency can be reduced by about at least 66% and 33% for
Fourfold increase in the number of VCs have only a marginal effect in reducing average latency.
Effect of latency reduction is higher in the algorithms with no VCs (i.e.
2% | 4% | 6% | 8% | |||
67 (0.40) | 63 (0.40) | 55 (0.30) | 55 (0.30) | 55 (0.25) | ||
81 (0.45) | 75 (0.40) | 69 (0.35) | 67 (0.30) | 65 (0.30) | ||
84 (0.45) | 78 (0.40) | 73 (0.35) | 71 (0.30) | 69 (0.30) | ||
66 (0.70) | 54 (0.60) | 40 (0.45) | 35 (0.45) | 33 (0.35) | ||
73 (0.75) | 60 (0.60) | 47 (0.50) | 38 (0.45) | 41 (0.35) | ||
76 (0.75) | 62 (0.60) | 49 (0.50) | 40 (0.45) | 44 (0.35) | ||
88 (0.95) | 82 (0.75) | 78 (0.70) | 76 (0.60) | 75 (0.55) | ||
92 (1.00) | 90 (0.80) | 85 (0.70) | 85 (0.65) | 82 (0.55) | ||
92 (1.00) | 91 (0.80) | 89 (0.70) | 87 (0.65) | 86 (0.55) |
Maximum latency reduction rate
Finally, the average latency of the three algorithms is compared under the same number of VCs (i.e. comparison of
−76 (0.60) | −75 (0.45) | −76 (0.40) | −75 (0.35) | −69 (0.35) | ||
96 (0.90) | 96 (0.75) | 94 (0.70) | 94 (0.60) | 94 (0.50) |
Maximum latency reduction rate
From the above results, we can conclude that, for reducing average latency of packet transmission, the reduction of hop count by the passage of faulty nodes, not always detour, is more effective than the avoidance of congestion using additional VCs.
To evaluate the overhead of additional circuits such as switches, buffers, and links in the proposed approach, we designed two routers for
From the EDA tool, the router for
We have introduced a novel approach for the design of fault-tolerant routing algorithms in 2D mesh NoCs. In contrast to the common idea of detouring faulty nodes, our approach allows passing through them with the slight modification of NoC architecture. We have provided a general methodology for designing fault-tolerant routing algorithms with the passage of faulty nodes, and as a design example, we have described the XY-based routing algorithm, showing how to prevent deadlocks in the routing rules. The XY-based routing algorithm allows passage of faulty nodes in the x-directional movement if the current and destination nodes are on the same row, while always allows in the y-directional movement.
To demonstrate the effect of the XY-based routing algorithm, we measured the average latency of packet transmission by computer simulations and compared with those of the well-known region-based algorithms proposed by Fukushima et al. and Chalasani et al. The results revealed that the XY-based algorithm reduced average latency of Chalasani’s algorithm by about 79% without additional VCs and 94% with the same number of VCs. From the evaluation, we have found that passage is highly effective approach to reducing the average latency rather than employing VCs for congestion avoidance. We have also designed router circuit for the XY-based algorithm and showed that the overhead of additional circuit required for the proposed approach is substantially small compared with the overall router circuit.
As the passage of faulty nodes is a simple but effective approach, we have even more room to fully investigate the effect. For example, in this chapter, we selected popular XY routing as a base algorithm, which is a deterministic routing algorithm. Designing a new routing algorithm with the passage function based on some adaptive routing algorithm is a possible future research. As the passage is not limited to 2D mesh NoCs, designing passage-based fault-tolerant routing algorithms for other popular topology such as 2D torus, 3D mesh/torus is also one of the interesting future researches.
This work was supported by JSPS KAKENHI Grant Number JP18K11217.
Demand for computation power will never stop, and it is ever increasing year by year in a variety of scientific research fields. As can be seen in the modern multi-processor system-on-chips and many core systems [1, 2, 3], this makes computing hardware devices equip with hundreds or thousands of processor cores for providing high computation power by parallel processing on a chip. For the implementation of such highly-integrated parallel systems, Network-on-Chip (NoC) has emerged as a promising paradigm. In NoCs, each node (i.e. a processor core with a router) is connected by an on-chip network and communication among them are done by transferring packets on the network. Using global interconnection structure reduces the difficulty of wiring design and latency of signal transmission and offers high scalability, in comparison with point-to-point signal wires or shared busses [4].
One of the most important and fundamental issues that must be addressed for NoCs is fault-tolerant routing. Definitely, routing of packets plays a key role in parallel systems because it has significant impact on the overall system performance. Meanwhile, the occurrence of faults during system fabrication and run time is inevitable, and it is almost impossible to completely remove their adverse effects from the systems even if some redundancy is incorporated. A single faulty node disrupts packet routing between many pairs of nodes, resulting in the failure of the entire system. Besides, a deadlock (i.e. circular waiting of packets) will occur if an adopted routing algorithm is imperfect. Once the deadlock occurs, packets can never proceed to the destinations, and thus resulting in the malfunction of the entire system. Therefore, designing an efficient fault-tolerant routing algorithm with the property of deadlock-freeness is crucial for realizing dependable NoC systems with high communication performance.
So far, extensive research has been devoted to fault-tolerant routing not only for NoCs but for traditional parallel computers. Although there exist several basic approaches, as we reviewed in Section 2, the common idea of the fault-tolerant routing remains unchanged from the earliest, and it has been undoubtedly to detour faulty nodes. This is quite natural because the purpose of the fault-tolerant routing is to route packets from source to destination nodes without entering faulty parts. Meanwhile, it is also obvious that detouring faulty nodes increases the communication latency as the packet is misrouted apart from the minimal path to the destination. One may consider that the increase in the communication latency is very little. This is true if packets are routed without interfered by other packets. However, it can be substantial increase under the situation where a number of packets are routed simultaneously and thus frequently blocked by others.
In this chapter, we introduce a novel approach for the design of fault-tolerant routing algorithms. In contrast to the common idea of detouring faulty nodes, our approach allows passing through them with the slight modification of NoC architecture. We provide a general methodology for designing a fault-tolerant routing algorithm with the passage of faulty nodes. As a design example, we describe an XY-based routing algorithm with the passage function. By computer simulations, we reveal the communication performance of the algorithm under the condition of with and without Virtual Channels (VCs), in comparison with well-known region-based routing algorithms.
The rest of this chapter is organized as follows: Section 2 presents the architecture of NoC, the basis of packet routing, and the related works of fault-tolerant routing algorithms. Section 3 presents the basic idea of the proposed approach and XY-based fault-tolerant routing algorithm, inclusive of the proof of the deadlock-freeness. Section 4 presents the results of the performance evaluation. Finally, Section 5 concludes the chapter with some possible direction of future research.
Target NoC topology in this chapter is a popular 2D mesh which has nodes of
Architecture of 2D mesh NoC.
Figure 2 shows the block diagram of the router. In the typical wormhole routing adopted in NoCs, a packet is divided into a sequence of fixed-size units of data, called flits, and transferred by routers one after another. Each router consists of five input/output units, five routing circuits, a VCs allocator, a crossbar switch, and a switch allocator. When a head flit (i.e. a flit having routing information) is transferred to a router and stored into a buffer in the input unit, the following processes are applied.
An output port to which the flit is forwarded is determined by the routing circuit.
A VC (i.e. buffer) to be used is determined by the VC allocator.
The crossbar switch is set up by the switch allocator to connect the input unit and the output unit associated with the determined output port.
The flit is moved from the input to the output units.
Finally, the flit is forwarded to the corresponding input unit of the next router.
Architecture of router.
The incoming head flit moves to the next router at the fifth cycle if there are no contentions, and the subsequent flits follow it in a pipeline fashion. This is a standard five-cycle router [5]. If no VC is used in an adopted routing algorithm, the router is reduced to a four-cycle router, as the second process (i.e. VC allocation) is omitted.
In routing packets in accordance with a routing algorithm, the algorithm must care about the occurrence of deadlocks. Deadlock is a situation where packets wait on one another to release the buffers. Figure 3 shows an example of a deadlock. In this example, a packet A is routed to the node
Example of a deadlock.
There have been two approaches to preventing deadlocks; approaches with and without VCs. In the approach with VCs, the original network is multiplexed into several virtual networks by VCs. For example, in Figure 3, if packets A and C are supposed to be routed on a virtual network with a VC and packets B and D are on a different virtual network with other VC, then the circular waiting is decomposed and packets get to proceed to the destinations. In the approach without VCs, a routing algorithm is carefully designed so that deadlocks never occur in the original physical network. For example, in Figure 3, if packets A and C are routed via
Fault-tolerant routing has been the subject of extensive research not only for NoCs but for traditional parallel computers over the past few decades. Most of the existing fault-tolerant routing algorithms for 2D mesh networks fall into the following three categories: (1) those employ a routing table, (2) those relax the constraints of guaranteed delivery or deadlock-freeness, and (3) those define some form of fault information on routers and detour paths.
In the first category, a routing table is employed in each router to route packets to the destinations. Routing tables contain routing information such as next hops for destinations, status of the network, and/or fault information. Hsin et al. [6] proposed an algorithm which employs ant colony optimization for traffic balancing. Liu et al. [7] proposed an algorithm which introduces coarse and fine-grained look-ahead schemes to obtain the information of other routers within the range of four hops. This algorithm requires two VCs for each input/output port to route packets. Zhao et al. [8] proposed an algorithm to provide minimal paths using the information of whole network. In general, those algorithms offer flexible route selection; however, they require a large amount of circuits to implement a routing table and complex calculation mechanism to create/update the table in all routers.
In the second category, constraints of guaranteed delivery or deadlock-freeness is relaxed to ease the design of routing algorithms. Janfaza et al. [9] proposed an adaptive routing algorithm which employs timeout and packet reinjection. Information of intermediate nodes is recorded in each packet and two VCs are used to route packets. Sinha et al. [10] proposed an algorithm based on the common XY and YX routing. This algorithm allows U-turn using several VCs. Wang et al. [11] proposed an algorithm which relaxes transmission accuracy for the applications that allow lossy communication. This algorithm discards conflicting approximate flits without retransmission and recovers them after packet transmission. Those algorithms are imperfect in that 100% packet reachability or deadlock-freeness are not guaranteed by the routing algorithms. Retransmission of packets generally results in a high communication latency.
In the third category, some form of fault information is defined for routers to detour faulty parts. Usually, clusters of faulty nodes, called fault blocks, are defined in the networks with the detour paths. Chen et al. [12], Holsmark et al. [13], Fu et al. [14], and Fukushima et al. [15] proposed routing algorithms which generate rectangular fault blocks and detour them without using VCs. Wu [16] and Chalasani et al. [17] proposed routing algorithms which can deal with convex and nonconvex fault blocks, respectively. In [17], four VCs are used to choose shorter detour paths. Those algorithms called region-based algorithms provide simple but strict routing rules to guarantee the deadlock-freeness and 100% packet reachability, and thus, they can be implemented as a small circuit in the routing circuit of each router. They are practical and suitable for NoCs. However, one drawback is that fault blocks may include several non-faulty nodes, which are to be deactivated (i.e. unused nodes); therefore, the number of unused nodes and the length of detour paths are prone to increase if there exist a number of faulty nodes in the network.
Although extensive research has been devoted to designing fault-tolerant routing algorithms inclusive of the above ones, the common idea remains unchanged from the earliest, and it has been undoubtedly to detour faulty nodes. If a packet must detour a faulty node
Motivated by the problem presented in the previous section, we introduce a novel approach based on the opposite idea of the common approach; our approach allows packets to pass through the faulty nodes with slight modification of NoC architecture (originally proposed in [18]). Basic idea behind this approach is to reduce communication latency by saving detouring as much as possible.
Figure 4 shows the modified NoC architecture for supporting the proposed approach. Four electrical switches, bypass links, buffers to store one flit are added around each router. Each switch has two states, either normal or passage, as shown in this figure. In the state of passage, packets from the neighbor node are input to the bypass link not to the node. The switch states can be determined easily, once the node is tested and judged as faulty or not. In other words, they are determined so that the node becomes passage state if it is faulty or remains normal state otherwise. It is worth to note that buffers can be removed if packets are transmitted between routers in an asynchronous way.
Modified NoC architecture.
Here, we provide a design methodology for fault-tolerant routing algorithms based on the passage of faulty nodes.
First, we clarify the fault model. A common assumption is made for faults [6, 12, 13, 14, 15, 16, 18, 19]; that is, permanent faults are considered to be associated only with nodes. In practice, the probabilities of links, switches, and buffers being faulty are not zero, though they will be substantially small because of the simplicity of their circuits [19]. For the faults on those circuits, one can employ some popular redundancy technique such as duplication and triplication if necessary.
Below is the general methodology for designing fault-tolerant routing algorithms with the passage function.
As a design example, we introduce a new fault-tolerant routing algorithm based on the popular dimension order routing (i.e. XY routing for 2D meshes) [18]. In the following, we explain the details of each step in the design methodology.
In Step 1, we choose XY routing as a base routing algorithm. In XY routing, packets first proceed along x-direction until they reach the nodes having the same x-coordinates as the destinations, then proceed to the destinations along y-direction without changing the x-coordinates.
In Step 2, we must consider the case where passage must be restricted. For example, suppose that a packet moves from node
Then, we need to consider the case where a faulty node is on the south boundary of the network. In this case, packets cannot detour it through the south side, as they face the south boundary. To cope with this, we give the following definitions.
The process in Definition 2 is repeated until no SF nodes are generated. For SF nodes, we give a new routing rule such that packets must detour them through the north side.
In Step 3, we check the deadlock-freeness of the resultant routing algorithm
Example of a possible deadlock.
To cope with the deadlock, we give the following definitions.
For the newly generated SF nodes in Definition 3, the processes in Definitions 2 and 3 are repeated until no SF nodes are generated.
Figure 6 illustrates examples of the SF area. In the case of Figure 6 (a), faulty node (
SF area for xy-based routing algorithm.
By the above definitions, the deadlock in Figure 5 can be solved. By Definition 3, two faulty nodes in Figure 5 are changed to SF nodes and the SF area is defined as shown in Figure 7. Then, two packets detour the SF nodes, not faulty nodes, through the north side and get to proceed to the destinations as shown in the figure.
Routing example without deadlocks.
Figure 8 describes the finally obtained proposed routing algorithm. In this figure, C and D represent a current and a destination node, respectively. The proposed routing algorithm allows packets to pass through faulty and SF nodes in the movement of x-directions only if C and D are on the same row (i.e. lines 8 and 18 in Figure 8), while it always allows passage in the movement of y-directions.
A pseudo-code of the proposed routing algorithm.
Next, we prove the deadlock-freeness of the proposed algorithm described in Figure 8. First, we define turns of packets.
Possible eight turns of packets.
For the clockwise direction, we show that an SW turn is never aligned with an NE turn. The SW turn occurs in a non-SF area; however, the NE turn never occurs in the area because it only occurs in an SF area. Conversely, the NE turn occurs in an SF area; however, the SW turn only occurs in a non-SF area. From the above, circular waiting never occurs in the clockwise direction.
For the counter-clockwise direction, we omit the proof because it is symmetrical to the proof for the clockwise direction.
Thus, the proposed routing algorithm is proved to be deadlock-free.□
To investigate the effect of the proposed approach, we have conducted computer simulations with a cycle-accurate custom simulator developed in C. This simulator accurately simulates the behavior of flits in all routers in a 2D mesh NoC. As explained in Section 2, if there are no contentions, each flit takes five (or four) cycles to move to the next node when VCs are used (or not used) in the adopted routing algorithm. Note that, as flits are transmitted in a pipeline fashion, a subsequent flit moves to the next node one cycle after the movement of the precedent flit if buffer space is available in the input unit of the router. It also takes one cycle to pass through a faulty node, as a buffer is placed on the bypass link.
Following three methods are evaluated in the simulations with the parameters listed in Table 1.
Fukushima’s method [15]: packets detour
Chalasani’s method [17]: packets detour
Our method [18]: packets can
Parameter | Value | Unit |
---|---|---|
Network size | 10 | Nodes |
Fault rate ( | 2, 4, 6, 8, 10 | % |
Packet length | 16 | Flits |
Packet generation rate ( | 0.05 | Packets/cycle/network |
Input (Output) buffer depth | 8 (1) | Flits |
Simulation (Stabilization) cycle | 50,000 (5000) | Cycles |
Simulation parameters.
The number of VCs required for each algorithm is different, and VCs can also be employed in the algorithms which require no VCs for the purpose of congestion avoidance. We use the notation of
In the simulations, faulty nodes are generated randomly according to the fault rate
To make a quantitative evaluation of average latency, we define maximum latency reduction rate of an algorithm
where
where
Figures 10–14 show the average latency as a function of packet generation rate
Average latency for
Average latency for
Average latency for
Average latency for
Average latency for
Figure 15 shows the average node utilization rate.
Average node utilization rate vs. fault rate.
For the results shown in Figures 10–14, we make performance comparison of the routing algorithms in the following three conditions.
The average latency of the original routing algorithms is compared numerically (i.e. comparison of
−94 (0.55) | −93 (0.45) | −92 (0.40) | −91 (0.35) | −89 (0.30) | ||
82 (0.75) | 82 (0.60) | 79 (0.50) | 81 (0.45) | 83 (0.40) |
Maximum latency reduction rate
Next, the average latency of the three algorithms is compared by increasing the number of VCs twofold, threefold, and fourfold from the original (i.e. comparison of
With twofold VCs, the average latency can be reduced by about at least 66% and 33% for
Fourfold increase in the number of VCs have only a marginal effect in reducing average latency.
Effect of latency reduction is higher in the algorithms with no VCs (i.e.
2% | 4% | 6% | 8% | |||
67 (0.40) | 63 (0.40) | 55 (0.30) | 55 (0.30) | 55 (0.25) | ||
81 (0.45) | 75 (0.40) | 69 (0.35) | 67 (0.30) | 65 (0.30) | ||
84 (0.45) | 78 (0.40) | 73 (0.35) | 71 (0.30) | 69 (0.30) | ||
66 (0.70) | 54 (0.60) | 40 (0.45) | 35 (0.45) | 33 (0.35) | ||
73 (0.75) | 60 (0.60) | 47 (0.50) | 38 (0.45) | 41 (0.35) | ||
76 (0.75) | 62 (0.60) | 49 (0.50) | 40 (0.45) | 44 (0.35) | ||
88 (0.95) | 82 (0.75) | 78 (0.70) | 76 (0.60) | 75 (0.55) | ||
92 (1.00) | 90 (0.80) | 85 (0.70) | 85 (0.65) | 82 (0.55) | ||
92 (1.00) | 91 (0.80) | 89 (0.70) | 87 (0.65) | 86 (0.55) |
Maximum latency reduction rate
Finally, the average latency of the three algorithms is compared under the same number of VCs (i.e. comparison of
−76 (0.60) | −75 (0.45) | −76 (0.40) | −75 (0.35) | −69 (0.35) | ||
96 (0.90) | 96 (0.75) | 94 (0.70) | 94 (0.60) | 94 (0.50) |
Maximum latency reduction rate
From the above results, we can conclude that, for reducing average latency of packet transmission, the reduction of hop count by the passage of faulty nodes, not always detour, is more effective than the avoidance of congestion using additional VCs.
To evaluate the overhead of additional circuits such as switches, buffers, and links in the proposed approach, we designed two routers for
From the EDA tool, the router for
We have introduced a novel approach for the design of fault-tolerant routing algorithms in 2D mesh NoCs. In contrast to the common idea of detouring faulty nodes, our approach allows passing through them with the slight modification of NoC architecture. We have provided a general methodology for designing fault-tolerant routing algorithms with the passage of faulty nodes, and as a design example, we have described the XY-based routing algorithm, showing how to prevent deadlocks in the routing rules. The XY-based routing algorithm allows passage of faulty nodes in the x-directional movement if the current and destination nodes are on the same row, while always allows in the y-directional movement.
To demonstrate the effect of the XY-based routing algorithm, we measured the average latency of packet transmission by computer simulations and compared with those of the well-known region-based algorithms proposed by Fukushima et al. and Chalasani et al. The results revealed that the XY-based algorithm reduced average latency of Chalasani’s algorithm by about 79% without additional VCs and 94% with the same number of VCs. From the evaluation, we have found that passage is highly effective approach to reducing the average latency rather than employing VCs for congestion avoidance. We have also designed router circuit for the XY-based algorithm and showed that the overhead of additional circuit required for the proposed approach is substantially small compared with the overall router circuit.
As the passage of faulty nodes is a simple but effective approach, we have even more room to fully investigate the effect. For example, in this chapter, we selected popular XY routing as a base algorithm, which is a deterministic routing algorithm. Designing a new routing algorithm with the passage function based on some adaptive routing algorithm is a possible future research. As the passage is not limited to 2D mesh NoCs, designing passage-based fault-tolerant routing algorithms for other popular topology such as 2D torus, 3D mesh/torus is also one of the interesting future researches.
This work was supported by JSPS KAKENHI Grant Number JP18K11217.
Authors are listed below with their open access chapters linked via author name:
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\\n\\n\\n\\n\\n\\n\\n\\n\\n\\nJocelyn Chanussot (chapter to be published soon...)
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\\n\\nIoannis Xenarios 2017, 2018
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\\n\\nXin-She Yang 2017, 2018
\\n\\nYulong Yin 2015, 2017, 2018
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\n\n\n\n\n\n\n\n\n\nJocelyn Chanussot (chapter to be published soon...)
\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nYuekun Lai
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\n\nKhalil Amine 2017, 2018
\n\nEwan Birney 2015-18
\n\nFrede Blaabjerg 2015-18
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\n\nMohamed Oukka 2016-18
\n\nBiswajeet Pradhan 2016-18
\n\nDirk Raes 2017, 2018
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\n\nLong Wang 2017, 2018
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HVAC systems can be classified into central and local systems according to multiple zones, location, and distribution. Primary HVAC equipment includes heating equipment, ventilation equipment, and cooling or air-conditioning equipment. Central HVAC systems locate away from buildings in a central equipment room and deliver the conditioned air by a delivery ductwork system. Central HVAC systems contain all-air, air-water, all-water systems. Two systems should be considered as central such as heating and cooling panels and water-source heat pumps. Local HVAC systems can be located inside a conditioned zone or adjacent to it and no requirement for ductwork. Local systems include local heating, local air-conditioning, local ventilation, and split systems.",book:{id:"6807",slug:"hvac-system",title:"HVAC System",fullTitle:"HVAC System"},signatures:"Shaimaa Seyam",authors:[{id:"247650",title:"M.Sc.",name:"Shaimaa",middleName:null,surname:"Seyam",slug:"shaimaa-seyam",fullName:"Shaimaa Seyam"},{id:"257733",title:"MSc.",name:"Shaimaa",middleName:null,surname:"Seyam",slug:"shaimaa-seyam",fullName:"Shaimaa Seyam"},{id:"395618",title:"Dr.",name:"Shaimaa",middleName:null,surname:"Seyam",slug:"shaimaa-seyam",fullName:"Shaimaa Seyam"}]},{id:"35256",title:"Gearbox Simulation Models with Gear and Bearing Faults",slug:"gearbox-simulation-models-with-gear-and-bearings-faults",totalDownloads:15011,totalCrossrefCites:12,totalDimensionsCites:16,abstract:null,book:{id:"1982",slug:"mechanical-engineering",title:"Mechanical Engineering",fullTitle:"Mechanical Engineering"},signatures:"Endo Hiroaki and Sawalhi Nader",authors:[{id:"113887",title:"Dr.",name:"Hiroaki",middleName:null,surname:"Endo",slug:"hiroaki-endo",fullName:"Hiroaki Endo"},{id:"113892",title:"Dr.",name:"Nader",middleName:null,surname:"Sawalhi",slug:"nader-sawalhi",fullName:"Nader Sawalhi"}]},{id:"35280",title:"Mechanical Engineering Education: Preschool to Graduate School",slug:"mechanical-engineering-education",totalDownloads:3230,totalCrossrefCites:0,totalDimensionsCites:0,abstract:null,book:{id:"1982",slug:"mechanical-engineering",title:"Mechanical Engineering",fullTitle:"Mechanical Engineering"},signatures:"Emily M. Hunt, Pamela Lockwood-Cooke and Michelle L. Pantoya",authors:[{id:"28270",title:"Prof.",name:"Michelle",middleName:null,surname:"Pantoya",slug:"michelle-pantoya",fullName:"Michelle Pantoya"},{id:"101001",title:"Dr.",name:"Emily",middleName:null,surname:"Hunt",slug:"emily-hunt",fullName:"Emily Hunt"},{id:"101003",title:"Dr.",name:"Pam",middleName:null,surname:"Lockwood",slug:"pam-lockwood",fullName:"Pam Lockwood"}]},{id:"54521",title:"Basic Design Methods of Heat Exchanger",slug:"basic-design-methods-of-heat-exchanger",totalDownloads:7091,totalCrossrefCites:3,totalDimensionsCites:4,abstract:"Heat exchangers are devices that transfer energy between fluids at different temperatures by heat transfer. These devices can be used widely both in daily life and industrial applications such as steam generators in thermal power plants, distillers in chemical industry, evaporators and condensers in HVAC applications and refrigeration process, heat sinks, automobile radiators and regenerators in gas turbine engines. This chapter discusses the basic design methods for two fluid heat exchangers.",book:{id:"5395",slug:"heat-exchangers-design-experiment-and-simulation",title:"Heat Exchangers",fullTitle:"Heat Exchangers - Design, Experiment and Simulation"},signatures:"Cüneyt Ezgi",authors:[{id:"187086",title:"Associate Prof.",name:"Cüneyt",middleName:null,surname:"Ezgi",slug:"cuneyt-ezgi",fullName:"Cüneyt Ezgi"}]}],onlineFirstChaptersFilter:{topicId:"121",limit:6,offset:0},onlineFirstChaptersCollection:[{id:"81716",title:"Groove Shape Optimization on Dry Gas Seals",slug:"groove-shape-optimization-on-dry-gas-seals",totalDownloads:7,totalDimensionsCites:0,doi:"10.5772/intechopen.103088",abstract:"In this paper, a topological optimum design for the shape of a groove in a dry gas seal is described. Dry gas seals are widely used in high speed and high pressure rotating machinery such as gas turbines, compressors, and so on because of their high reliability compared to other types of seals. However, recent requirements for reducing emission with further control of leakage are in order. With this background, we propose applying topological optimization to the groove shape in a dry gas seal to reduce its leakage while keeping its stiffness for safe operation. First, the method of topological optimum design as applied to the groove of a dry gas seal is explained via numerical analysis. Next, results of the topological optimization are shown via categorizing an optimum shape map. Finally, the mechanism of reducing the gas leakage with an optimized seal is discussed based on the prediction of the flow field using a CFD analysis.",book:{id:"10848",title:"Tribology of Machine Elements - Fundamentals and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/10848.jpg"},signatures:"Masayuki Ochiai and Yuki Sato"},{id:"81426",title:"Quality and Fatigue Assessment of Welded Railway Bridge Components by Testing",slug:"quality-and-fatigue-assessment-of-welded-railway-bridge-components-by-testing",totalDownloads:15,totalDimensionsCites:0,doi:"10.5772/intechopen.104439",abstract:"During a decades-long program from 1953 to 1990, the quality of welded joints in railway bridges in Poland was assessed and quantified. It was discovered that many welded joints have technological cracks, and their quality is poor, especially in old constructions. Nearly, 200 bridges were tested using X-ray examination. The number of joints tested was over 15,000; cracks were discovered in 400 welded joints in the 34 bridges tested. To solve the problem, repeated examinations on welded joints with imperfections were undertaken and laboratory fatigue tests were performed. The tests and numerical analysis allowed fatigue behavior and tensile stresses in welded butt splices with cover plates to be recognized and excluded such a structural solution in bridges. The existing discontinuities and imperfections in welded joints following many years in service show no growths or forming of new cracks, as the applied stresses are below the threshold fatigue strength. As a result of decades of service, steel bridges undergo functional aging, and their structural steels undergo structural aging. There is a need to both harmonize differentiated procedures and create national recommendations to assess their safe endurance. Therefore, of use may be the findings presented in the chapter.",book:{id:"11080",title:"Engineering Principles - Welding and Residual Stresses",coverURL:"https://cdn.intechopen.com/books/images_new/11080.jpg"},signatures:"Janusz Hołowaty and Bernard Wichtowski"},{id:"81430",title:"Engineering Challenges Associated with Welding Field Repairs",slug:"engineering-challenges-associated-with-welding-field-repairs",totalDownloads:15,totalDimensionsCites:0,doi:"10.5772/intechopen.104263",abstract:"Welding as technology exists in two worlds. Manufacturers execute designs typically based on professional society-backed standards. Repair service centers that administer field repairs where welding applications are required can sometimes have staff members with little formal education. The challenges of a technical manager seeking welded field repairs to equipment are significant and numerous. This chapter will seek to outline the process of executing a successful welding field repair by breaking down the analysis into three parts—(1) the identification of the engineering challenges associated with a specific job, including significant stresses, difficult materials or locations, and adequate piece preparation to ensure of weld integrity; (2) the ability to properly specify the type of repair, including knowledge of the types of weld junctions and preparations, the various types of welding processes and their features, weld types and associated drawing symbols, and the repair design and repair support process; and (3) the challenges for field engineers and technical managers in identifying weld defects, executing measures, and providing adequate examination and evaluation of weld quality in the field. This chapter tries to bridge the gap between the formal, engineered welds used in manufacturing and the sometimes-needed expediency of fieldwork.",book:{id:"11080",title:"Engineering Principles - Welding and Residual Stresses",coverURL:"https://cdn.intechopen.com/books/images_new/11080.jpg"},signatures:"Tyler J. McPheron and Robert M. Stwalley III"},{id:"81191",title:"Remote Nondestructive Thermal Control of Elastic Abrasive Cutting",slug:"remote-nondestructive-thermal-control-of-elastic-abrasive-cutting",totalDownloads:18,totalDimensionsCites:0,doi:"10.5772/intechopen.103115",abstract:"High temperatures during abrasive cutting lead to increased harmful gas emissions released into the environment, intensified cut-off wheel wear, microstructural changes in the machined material, and occurrence of thermal flaws. Temperature measurement in abrasive cutting is difficult due to the small size of the heated area (only tenths of mm2), high temperatures (above 1000°C), continuous change of the conditions within one cut-off cycle, large temperature gradient (more than 200°C), high cutting speed (above 50 m/s) and high mechanical load. The infrared thermography (IRT) application for thermal control of elastic abrasive cutting have been studied. The performed thermal measurements have been verified with the results obtained from the temperature models of workpiece, cut-off wheel, and cut piece depending on the conditions in elastic abrasive cutting of two structural steels C45 and 42Cr4. The parameters of effective abrasive cutting have been determined by applying multi-objective optimization.",book:{id:"10848",title:"Tribology of Machine Elements - Fundamentals and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/10848.jpg"},signatures:"Anna Stoynova, Irina Aleksandrova and Anatoliy Aleksandrov"},{id:"80933",title:"Center Stir Zone Investigations of Dissimilar AA6082, AA2014 and AA7075 Welds",slug:"center-stir-zone-investigations-of-dissimilar-aa6082-aa2014-and-aa7075-welds",totalDownloads:23,totalDimensionsCites:0,doi:"10.5772/intechopen.102652",abstract:"The study compares the mechanical and metallurgical properties of AA6082, AA2014, and AA7075 dissimilar friction stir welded aluminum 6 mm plates. The alloys AA2014 and AA7075 are aerospace grade, whereas AA6082 is structural grade. The AA6082/AA7075, AA6082/AA2014, and AA2014/AA7075 joints were formed with optimized parameters of 2° tilt angle, 900 rpm rotational speed, and 80 mm/min feed rate with a constant axial force of 20 kN. Then, to investigate the stir zone properties of the joints, the tensile strength, microstructural, and hardness variations across the weld were revealed. Despite the fact that the strength of each joint was varied, the fine grain in the stir zone across the weld and advancing side weld/HAZ failure in tensile failure were studied for all welds. Further EBSD analysis revealed fine grains for the formation of its center stir zone due to dynamic recovery recrystallization during welding.",book:{id:"11080",title:"Engineering Principles - Welding and Residual Stresses",coverURL:"https://cdn.intechopen.com/books/images_new/11080.jpg"},signatures:"K.T. Thilagham and S. Muthukumaran"},{id:"80882",title:"Use of Hybrid Methods (Hole-Drilling and Ring-Core) for the Analysis of the RS on Welded Joints",slug:"use-of-hybrid-methods-hole-drilling-and-ring-core-for-the-analysis-of-the-rs-on-welded-joints",totalDownloads:25,totalDimensionsCites:0,doi:"10.5772/intechopen.102051",abstract:"The hybrid methods (HMs) for the residual stress (RS) analysis, such as the well-known hole-drilling method (HDM) and the ring-core method (RCM), have been widely developed since 80’. They are mechanical methods based on the partial relaxation of the RSs that occur when a proper geometry variation of the analysed component is introduced by drilling a hole (HDM) or a proper annular groove (RCM). The RS computation is performed by measuring the strains relaxed on surface and then by combine properly such measured strains with the influence coefficients previously computed accurately by using a numerical codes that consider the geometry of the particular component to be examined. In such a manner, the HMs can be potentially applied to any RS distribution independently from the cause that have caused them. In more detail, the HMs can be used for the analysis of the RS on welded joint by using both classical welding methods, as MIG or TIG processes, or modern methods as friction stir welding, etc. In the present chapter, after a brief presentation of the theory of the HMs, their application to various cases of welding joints are treated, and the possible limitation are discussed.",book:{id:"11080",title:"Engineering Principles - Welding and Residual Stresses",coverURL:"https://cdn.intechopen.com/books/images_new/11080.jpg"},signatures:"Bernardo Zuccarello"}],onlineFirstChaptersTotal:20},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:87,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:98,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:27,numberOfPublishedChapters:287,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:9,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:139,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:129,numberOfOpenTopics:0,numberOfUpcomingTopics:2,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!1},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:107,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:10,numberOfPublishedChapters:103,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:12,numberOfOpenTopics:2,numberOfUpcomingTopics:1,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:0,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!1},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:11,numberOfOpenTopics:4,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}},{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}}]},series:{item:{id:"11",title:"Biochemistry",doi:"10.5772/intechopen.72877",issn:"2632-0983",scope:"Biochemistry, the study of chemical transformations occurring within living organisms, impacts all areas of life sciences, from molecular crystallography and genetics to ecology, medicine, and population biology. 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Dr. Blumenberg’s research is focused on the epidermis, expression of keratin genes, transcription profiling, keratinocyte differentiation, inflammatory diseases and cancers, and most recently the effects of the microbiome on the skin. 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Other positions she has held at the university include Vice-Dean of Master Programs, Vice-Dean of the Degree in Biology and Vice-Dean for Mobility and Enterprise and Engagement at the Faculty of Science (University of Alicante). She received her Bachelor in Biology in 1998 (University of Alicante) and her PhD in 2003 (Biochemistry, University of Alicante). She undertook post-doctoral research at the University of East Anglia (Norwich, U.K. 2004-2005; 2007-2008).\nHer multidisciplinary research focuses on investigating archaea and their potential applications in biotechnology. She has an H-index of 21. She has authored one patent and has published more than 70 indexed papers and around 60 book chapters.\nShe has contributed to more than 150 national and international meetings during the last 15 years. Her research interests include archaea metabolism, enzymes purification and characterization, gene regulation, carotenoids and bioplastics production, antioxidant\ncompounds, waste water treatments, and brines bioremediation.\nRosa María’s other roles include editorial board member for several journals related\nto biochemistry, reviewer for more than 60 journals (biochemistry, molecular biology, biotechnology, chemistry and microbiology) and president of several organizing committees in international meetings related to the N-cycle or respiratory processes.",institutionString:null,institution:{name:"University of Alicante",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null},{id:"15",title:"Chemical Biology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/15.jpg",isOpenForSubmission:!0,editor:{id:"441442",title:"Dr.",name:"Şükrü",middleName:null,surname:"Beydemir",slug:"sukru-beydemir",fullName:"Şükrü Beydemir",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003GsUoIQAV/Profile_Picture_1634557147521",biography:"Dr. Şükrü Beydemir obtained a BSc in Chemistry in 1995 from Yüzüncü Yıl University, MSc in Biochemistry in 1998, and PhD in Biochemistry in 2002 from Atatürk University, Turkey. He performed post-doctoral studies at Max-Planck Institute, Germany, and University of Florence, Italy in addition to making several scientific visits abroad. He currently works as a Full Professor of Biochemistry in the Faculty of Pharmacy, Anadolu University, Turkey. Dr. Beydemir has published over a hundred scientific papers spanning protein biochemistry, enzymology and medicinal chemistry, reviews, book chapters and presented several conferences to scientists worldwide. He has received numerous publication awards from various international scientific councils. He serves in the Editorial Board of several international journals. 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He is a member of the Turkish Biochemical Society, American Chemical Society, and German Genetics society. Dr. Ekinci published around ninety scientific papers, reviews and book chapters, and presented several conferences to scientists. He has received numerous publication awards from several scientific councils. 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He worked on the structure-function relationships of glycoconjugates and his main project was the investigations on the biological roles of the de-N-glycosylation enzymes (Endo-N-acetyl-β-D-glucosaminidase and peptide-N4-(N-acetyl-β-glucosaminyl) asparagine amidase). From 2002 he contributes to the understanding of the Blood-brain barrier functioning using proteomics approaches. He has published more than 70 papers. 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Since then, he has been working as an Adjunct Professor in the same Department at the University of Pavia. His research activity during the first years was primarily focused on the purification and structural characterization of enzymes from animal and plant sources. During this period, Prof. Iadarola familiarized himself with the conventional techniques used in column chromatography, spectrophotometry, manual Edman degradation, and electrophoresis). Since 1995, he has been working on: i) the determination in biological fluids (serum, urine, bronchoalveolar lavage, sputum) of proteolytic activities involved in the degradation processes of connective tissue matrix, and ii) on the identification of biological markers of lung diseases. 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He also obtained an MSc in Molecular and Genetic Medicine, and a Ph.D. in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also completed a short-term fellowship in Pediatric Clinical Immunology and Bone Marrow Transplantation at Newcastle General Hospital, England. Dr. Rezaei is a Full Professor of Immunology and Vice Dean of International Affairs and Research, at the School of Medicine, Tehran University of Medical Sciences, and the co-founder and head of the Research Center for Immunodeficiencies. He is also the founding president of the Universal Scientific Education and Research Network (USERN). Dr. Rezaei has directed more than 100 research projects and has designed and participated in several international collaborative projects. He is an editor, editorial assistant, or editorial board member of more than forty international journals. He has edited more than 50 international books, presented more than 500 lectures/posters in congresses/meetings, and published more than 1,100 scientific papers in international journals.",institutionString:"Tehran University of Medical Sciences",institution:{name:"Tehran University of Medical Sciences",country:{name:"Iran"}}},{id:"180733",title:"Dr.",name:"Jean",middleName:null,surname:"Engohang-Ndong",slug:"jean-engohang-ndong",fullName:"Jean Engohang-Ndong",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/180733/images/system/180733.png",biography:"Dr. Jean Engohang-Ndong was born and raised in Gabon. After obtaining his Associate Degree of Science at the University of Science and Technology of Masuku, Gabon, he continued his education in France where he obtained his BS, MS, and Ph.D. in Medical Microbiology. He worked as a post-doctoral fellow at the Public Health Research Institute (PHRI), Newark, NJ for four years before accepting a three-year faculty position at Brigham Young University-Hawaii. Dr. Engohang-Ndong is a tenured faculty member with the academic rank of Full Professor at Kent State University, Ohio, where he teaches a wide range of biological science courses and pursues his research in medical and environmental microbiology. Recently, he expanded his research interest to epidemiology and biostatistics of chronic diseases in Gabon.",institutionString:"Kent State University",institution:{name:"Kent State University",country:{name:"United States of America"}}},{id:"188773",title:"Prof.",name:"Emmanuel",middleName:null,surname:"Drouet",slug:"emmanuel-drouet",fullName:"Emmanuel Drouet",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/188773/images/system/188773.png",biography:"Emmanuel Drouet, PharmD, is a Professor of Virology at the Faculty of Pharmacy, the University Grenoble-Alpes, France. As a head scientist at the Institute of Structural Biology in Grenoble, Dr. Drouet’s research investigates persisting viruses in humans (RNA and DNA viruses) and the balance with our host immune system. He focuses on these viruses’ effects on humans (both their impact on pathology and their symbiotic relationships in humans). He has an excellent track record in the herpesvirus field, and his group is engaged in clinical research in the field of Epstein-Barr virus diseases. He is the editor of the online Encyclopedia of Environment and he coordinates the Universal Health Coverage education program for the BioHealth Computing Schools of the European Institute of Science.",institutionString:null,institution:{name:"Grenoble Alpes University",country:{name:"France"}}},{id:"131400",title:"Prof.",name:"Alfonso J.",middleName:null,surname:"Rodriguez-Morales",slug:"alfonso-j.-rodriguez-morales",fullName:"Alfonso J. Rodriguez-Morales",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/131400/images/system/131400.png",biography:"Dr. Rodriguez-Morales is an expert in tropical and emerging diseases, particularly zoonotic and vector-borne diseases (especially arboviral diseases). He is the president of the Travel Medicine Committee of the Pan-American Infectious Diseases Association (API), as well as the president of the Colombian Association of Infectious Diseases (ACIN). He is a member of the Committee on Tropical Medicine, Zoonoses, and Travel Medicine of ACIN. He is a vice-president of the Latin American Society for Travel Medicine (SLAMVI) and a Member of the Council of the International Society for Infectious Diseases (ISID). Since 2014, he has been recognized as a Senior Researcher, at the Ministry of Science of Colombia. He is a professor at the Faculty of Medicine of the Fundacion Universitaria Autonoma de las Americas, in Pereira, Risaralda, Colombia. He is an External Professor, Master in Research on Tropical Medicine and International Health, Universitat de Barcelona, Spain. He is also a professor at the Master in Clinical Epidemiology and Biostatistics, Universidad Científica del Sur, Lima, Peru. In 2021 he has been awarded the “Raul Isturiz Award” Medal of the API. Also, in 2021, he was awarded with the “Jose Felix Patiño” Asclepius Staff Medal of the Colombian Medical College, due to his scientific contributions to COVID-19 during the pandemic. He is currently the Editor in Chief of the journal Travel Medicine and Infectious Diseases. His Scopus H index is 47 (Google Scholar H index, 68).",institutionString:"Institución Universitaria Visión de las Américas, Colombia",institution:null},{id:"332819",title:"Dr.",name:"Chukwudi Michael",middleName:"Michael",surname:"Egbuche",slug:"chukwudi-michael-egbuche",fullName:"Chukwudi Michael Egbuche",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/332819/images/14624_n.jpg",biography:"I an Dr. Chukwudi Michael Egbuche. I am a Senior Lecturer in the Department of Parasitology and Entomology, Nnamdi Azikiwe University, Awka.",institutionString:null,institution:{name:"Nnamdi Azikiwe University",country:{name:"Nigeria"}}},{id:"284232",title:"Mr.",name:"Nikunj",middleName:"U",surname:"Tandel",slug:"nikunj-tandel",fullName:"Nikunj Tandel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/284232/images/8275_n.jpg",biography:'Mr. Nikunj Tandel has completed his Master\'s degree in Biotechnology from VIT University, India in the year of 2012. He is having 8 years of research experience especially in the field of malaria epidemiology, immunology, and nanoparticle-based drug delivery system against the infectious diseases, autoimmune disorders and cancer. He has worked for the NIH funded-International Center of Excellence in Malaria Research project "Center for the study of complex malaria in India (CSCMi)" in collaboration with New York University. The preliminary objectives of the study are to understand and develop the evidence-based tools and interventions for the control and prevention of malaria in different sites of the INDIA. Alongside, with the help of next-generation genomics study, the team has studied the antimalarial drug resistance in India. Further, he has extended his research in the development of Humanized mice for the study of liver-stage malaria and identification of molecular marker(s) for the Artemisinin resistance. At present, his research focuses on understanding the role of B cells in the activation of CD8+ T cells in malaria. Received the CSIR-SRF (Senior Research Fellow) award-2018, FIMSA (Federation of Immunological Societies of Asia-Oceania) Travel Bursary award to attend the IUIS-IIS-FIMSA Immunology course-2019',institutionString:"Nirma University",institution:{name:"Nirma University",country:{name:"India"}}},{id:"334383",title:"Ph.D.",name:"Simone",middleName:"Ulrich",surname:"Ulrich Picoli",slug:"simone-ulrich-picoli",fullName:"Simone Ulrich Picoli",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/334383/images/15919_n.jpg",biography:"Graduated in Pharmacy from Universidade Luterana do Brasil (1999), Master in Agricultural and Environmental Microbiology from Federal University of Rio Grande do Sul (2002), Specialization in Clinical Microbiology from Universidade de São Paulo, USP (2007) and PhD in Sciences in Gastroenterology and Hepatology (2012). She is currently an Adjunct Professor at Feevale University in Medicine and Biomedicine courses and a permanent professor of the Academic Master\\'s Degree in Virology. She has experience in the field of Microbiology, with an emphasis on Bacteriology, working mainly on the following topics: bacteriophages, bacterial resistance, clinical microbiology and food microbiology.",institutionString:null,institution:{name:"Universidade Feevale",country:{name:"Brazil"}}},{id:"229220",title:"Dr.",name:"Amjad",middleName:"Islam",surname:"Aqib",slug:"amjad-aqib",fullName:"Amjad Aqib",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/229220/images/system/229220.png",biography:"Dr. Amjad Islam Aqib obtained a DVM and MSc (Hons) from University of Agriculture Faisalabad (UAF), Pakistan, and a PhD from the University of Veterinary and Animal Sciences Lahore, Pakistan. Dr. Aqib joined the Department of Clinical Medicine and Surgery at UAF for one year as an assistant professor where he developed a research laboratory designated for pathogenic bacteria. Since 2018, he has been Assistant Professor/Officer in-charge, Department of Medicine, Manager Research Operations and Development-ORIC, and President One Health Club at Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Pakistan. He has nearly 100 publications to his credit. His research interests include epidemiological patterns and molecular analysis of antimicrobial resistance and modulation and vaccine development against animal pathogens of public health concern.",institutionString:"Cholistan University of Veterinary and Animal Sciences",institution:null},{id:"62900",title:"Prof.",name:"Fethi",middleName:null,surname:"Derbel",slug:"fethi-derbel",fullName:"Fethi Derbel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/62900/images/system/62900.jpeg",biography:"Professor Fethi Derbel was born in 1960 in Tunisia. He received his medical degree from the Sousse Faculty of Medicine at Sousse, University of Sousse, Tunisia. He completed his surgical residency in General Surgery at the University Hospital Farhat Hached of Sousse and was a member of the Unit of Liver Transplantation in the University of Rennes, France. He then worked in the Department of Surgery at the Sahloul University Hospital in Sousse. Professor Derbel is presently working at the Clinique les Oliviers, Sousse, Tunisia. His hospital activities are mostly concerned with laparoscopic, colorectal, pancreatic, hepatobiliary, and gastric surgery. He is also very interested in hernia surgery and performs ventral hernia repairs and inguinal hernia repairs. He has been a member of the GREPA and Tunisian Hernia Society (THS). During his residency, he managed patients suffering from diabetic foot, and he was very interested in this pathology. For this reason, he decided to coordinate a book project dealing with the diabetic foot. Professor Derbel has published many articles in journals and collaborates intensively with IntechOpen Access Publisher as an editor.",institutionString:"Clinique les Oliviers",institution:null},{id:"300144",title:"Dr.",name:"Meriem",middleName:null,surname:"Braiki",slug:"meriem-braiki",fullName:"Meriem Braiki",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/300144/images/system/300144.jpg",biography:"Dr. Meriem Braiki is a specialist in pediatric surgeon from Tunisia. She was born in 1985. She received her medical degree from the University of Medicine at Sousse, Tunisia. She achieved her surgical residency training periods in Pediatric Surgery departments at University Hospitals in Monastir, Tunis and France.\r\nShe is currently working at the Pediatric surgery department, Sidi Bouzid Hospital, Tunisia. Her hospital activities are mostly concerned with laparoscopic, parietal, urological and digestive surgery. She has published several articles in diffrent journals.",institutionString:"Sidi Bouzid Regional Hospital",institution:null},{id:"229481",title:"Dr.",name:"Erika M.",middleName:"Martins",surname:"de Carvalho",slug:"erika-m.-de-carvalho",fullName:"Erika M. de Carvalho",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/229481/images/6397_n.jpg",biography:null,institutionString:null,institution:{name:"Oswaldo Cruz Foundation",country:{name:"Brazil"}}},{id:"186537",title:"Prof.",name:"Tonay",middleName:null,surname:"Inceboz",slug:"tonay-inceboz",fullName:"Tonay Inceboz",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/186537/images/system/186537.jfif",biography:"I was graduated from Ege University of Medical Faculty (Turkey) in 1988 and completed his Med. PhD degree in Medical Parasitology at the same university. I became an Associate Professor in 2008 and Professor in 2014. I am currently working as a Professor at the Department of Medical Parasitology at Dokuz Eylul University, Izmir, Turkey.\n\nI have given many lectures, presentations in different academic meetings. I have more than 60 articles in peer-reviewed journals, 18 book chapters, 1 book editorship.\n\nMy research interests are Echinococcus granulosus, Echinococcus multilocularis (diagnosis, life cycle, in vitro and in vivo cultivation), and Trichomonas vaginalis (diagnosis, PCR, and in vitro cultivation).",institutionString:"Dokuz Eylül University",institution:{name:"Dokuz Eylül University",country:{name:"Turkey"}}},{id:"71812",title:"Prof.",name:"Hanem Fathy",middleName:"Fathy",surname:"Khater",slug:"hanem-fathy-khater",fullName:"Hanem Fathy Khater",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/71812/images/1167_n.jpg",biography:"Prof. Khater is a Professor of Parasitology at Benha University, Egypt. She studied for her doctoral degree, at the Department of Entomology, College of Agriculture, Food and Natural Resources, University of Missouri, Columbia, USA. She has completed her Ph.D. degrees in Parasitology in Egypt, from where she got the award for “the best scientific Ph.D. dissertation”. She worked at the School of Biological Sciences, Bristol, England, the UK in controlling insects of medical and veterinary importance as a grant from Newton Mosharafa, the British Council. Her research is focused on searching of pesticides against mosquitoes, house flies, lice, green bottle fly, camel nasal botfly, soft and hard ticks, mites, and the diamondback moth as well as control of several parasites using safe and natural materials to avoid drug resistances and environmental contamination.",institutionString:null,institution:{name:"Banha University",country:{name:"Egypt"}}},{id:"99780",title:"Prof.",name:"Omolade",middleName:"Olayinka",surname:"Okwa",slug:"omolade-okwa",fullName:"Omolade Okwa",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/99780/images/system/99780.jpg",biography:"Omolade Olayinka Okwa is presently a Professor of Parasitology at Lagos State University, Nigeria. She has a PhD in Parasitology (1997), an MSc in Cellular Parasitology (1992), and a BSc (Hons) Zoology (1990) all from the University of Ibadan, Nigeria. She teaches parasitology at the undergraduate and postgraduate levels. She was a recipient of a Commonwealth fellowship supported by British Council tenable at the Centre for Entomology and Parasitology (CAEP), Keele University, United Kingdom between 2004 and 2005. She was awarded an Honorary Visiting Research Fellow at the same university from 2005 to 2007. \nShe has been an external examiner to the Department of Veterinary Microbiology and Parasitology, University of Ibadan, MSc programme between 2010 and 2012. She is a member of the Nigerian Society of Experimental Biology (NISEB), Parasitology and Public Health Society of Nigeria (PPSN), Science Association of Nigeria (SAN), Zoological Society of Nigeria (ZSN), and is Vice Chairperson of the Organisation of Women in Science (OWSG), LASU chapter. She served as Head of Department of Zoology and Environmental Biology, Lagos State University from 2007 to 2010 and 2014 to 2016. She is a reviewer for several local and international journals such as Unilag Journal of Science, Libyan Journal of Medicine, Journal of Medicine and Medical Sciences, and Annual Research and Review in Science. \nShe has authored 45 scientific research publications in local and international journals, 8 scientific reviews, 4 books, and 3 book chapters, which includes the books “Malaria Parasites” and “Malaria” which are IntechOpen access publications.",institutionString:"Lagos State University",institution:{name:"Lagos State University",country:{name:"Nigeria"}}},{id:"273100",title:"Dr.",name:"Vijay",middleName:null,surname:"Gayam",slug:"vijay-gayam",fullName:"Vijay Gayam",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/273100/images/system/273100.jpeg",biography:"Dr. Vijay Bhaskar Reddy Gayam is currently practicing as an internist at Interfaith Medical Center in Brooklyn, New York, USA. He is also a Clinical Assistant Professor at the SUNY Downstate University Hospital and Adjunct Professor of Medicine at the American University of Antigua. He is a holder of an M.B.B.S. degree bestowed to him by Osmania Medical College and received his M.D. at Interfaith Medical Center. His career goals thus far have heavily focused on direct patient care, medical education, and clinical research. He currently serves in two leadership capacities; Assistant Program Director of Medicine at Interfaith Medical Center and as a Councilor for the American\r\nFederation for Medical Research. As a true academician and researcher, he has more than 50 papers indexed in international peer-reviewed journals. He has also presented numerous papers in multiple national and international scientific conferences. His areas of research interest include general internal medicine, gastroenterology and hepatology. He serves as an editor, editorial board member and reviewer for multiple international journals. His research on Hepatitis C has been very successful and has led to multiple research awards, including the 'Equity in Prevention and Treatment Award” from the New York Department of Health Viral Hepatitis Symposium (2018) and the 'Presidential Poster Award” awarded to him by the American College of Gastroenterology (2018). He was also awarded 'Outstanding Clinician in General Medicine” by Venus International Foundation for his extensive research expertise and services, perform over and above the standard expected in the advancement of healthcare, patient safety and quality of care.",institutionString:"Interfaith Medical Center",institution:{name:"Interfaith Medical Center",country:{name:"United States of America"}}},{id:"93517",title:"Dr.",name:"Clement",middleName:"Adebajo",surname:"Meseko",slug:"clement-meseko",fullName:"Clement Meseko",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/93517/images/system/93517.jpg",biography:"Dr. Clement Meseko obtained DVM and PhD degree in Veterinary Medicine and Virology respectively. He has worked for over 20 years in both private and public sectors including the academia, contributing to knowledge and control of infectious disease. Through the application of epidemiological skill, classical and molecular virological skills, he investigates viruses of economic and public health importance for the mitigation of the negative impact on people, animal and the environment in the context of Onehealth. \r\nDr. Meseko’s field experience on animal and zoonotic diseases and pathogen dynamics at the human-animal interface over the years shaped his carrier in research and scientific inquiries. He has been part of the investigation of Highly Pathogenic Avian Influenza incursions in sub Saharan Africa and monitors swine Influenza (Pandemic influenza Virus) agro-ecology and potential for interspecies transmission. He has authored and reviewed a number of journal articles and book chapters.",institutionString:"National Veterinary Research Institute",institution:{name:"National Veterinary Research Institute",country:{name:"Nigeria"}}},{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",biography:"Professor Dr. Shailendra K. Saxena is a vice dean and professor at King George's Medical University, Lucknow, India. His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research work has been published in various high-impact factor journals (Science, PNAS, Nature Medicine) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. Dr. Saxena is a fellow of various international societies/academies including the Royal College of Pathologists, United Kingdom; Royal Society of Medicine, London; Royal Society of Biology, United Kingdom; Royal Society of Chemistry, London; and Academy of Translational Medicine Professionals, Austria. He was named a Global Leader in Science by The Scientist. He is also an international opinion leader/expert in vaccination for Japanese encephalitis by IPIC (UK).",institutionString:"King George's Medical University",institution:{name:"King George's Medical University",country:{name:"India"}}},{id:"94928",title:"Dr.",name:"Takuo",middleName:null,surname:"Mizukami",slug:"takuo-mizukami",fullName:"Takuo Mizukami",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/94928/images/6402_n.jpg",biography:null,institutionString:null,institution:{name:"National Institute of Infectious Diseases",country:{name:"Japan"}}},{id:"233433",title:"Dr.",name:"Yulia",middleName:null,surname:"Desheva",slug:"yulia-desheva",fullName:"Yulia Desheva",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/233433/images/system/233433.png",biography:"Dr. Yulia Desheva is a leading researcher at the Institute of Experimental Medicine, St. Petersburg, Russia. She is a professor in the Stomatology Faculty, St. Petersburg State University. She has expertise in the development and evaluation of a wide range of live mucosal vaccines against influenza and bacterial complications. Her research interests include immunity against influenza and COVID-19 and the development of immunization schemes for high-risk individuals.",institutionString:'Federal State Budgetary Scientific Institution "Institute of Experimental Medicine"',institution:null},{id:"238958",title:"Mr.",name:"Atamjit",middleName:null,surname:"Singh",slug:"atamjit-singh",fullName:"Atamjit Singh",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/238958/images/6575_n.jpg",biography:null,institutionString:null,institution:null},{id:"333753",title:"Dr.",name:"Rais",middleName:null,surname:"Ahmed",slug:"rais-ahmed",fullName:"Rais Ahmed",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/333753/images/20168_n.jpg",biography:null,institutionString:null,institution:null},{id:"252058",title:"M.Sc.",name:"Juan",middleName:null,surname:"Sulca",slug:"juan-sulca",fullName:"Juan Sulca",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/252058/images/12834_n.jpg",biography:null,institutionString:null,institution:null},{id:"191392",title:"Dr.",name:"Marimuthu",middleName:null,surname:"Govindarajan",slug:"marimuthu-govindarajan",fullName:"Marimuthu Govindarajan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/191392/images/5828_n.jpg",biography:"Dr. M. 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He serves as an editorial board member in various national and international scientific journals.",institutionString:null,institution:null},{id:"274660",title:"Dr.",name:"Damodar",middleName:null,surname:"Paudel",slug:"damodar-paudel",fullName:"Damodar Paudel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/274660/images/8176_n.jpg",biography:"I am DrDamodar Paudel,currently working as consultant Physician in Nepal police Hospital.",institutionString:null,institution:null},{id:"241562",title:"Dr.",name:"Melvin",middleName:null,surname:"Sanicas",slug:"melvin-sanicas",fullName:"Melvin Sanicas",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/241562/images/6699_n.jpg",biography:null,institutionString:null,institution:null},{id:"337446",title:"Dr.",name:"Maria",middleName:null,surname:"Zavala-Colon",slug:"maria-zavala-colon",fullName:"Maria Zavala-Colon",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Puerto Rico, Medical Sciences Campus",country:{name:"United States of America"}}},{id:"338856",title:"Mrs.",name:"Nur Alvira",middleName:null,surname:"Pascawati",slug:"nur-alvira-pascawati",fullName:"Nur Alvira Pascawati",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Universitas Respati Yogyakarta",country:{name:"Indonesia"}}},{id:"441116",title:"Dr.",name:"Jovanka M.",middleName:null,surname:"Voyich",slug:"jovanka-m.-voyich",fullName:"Jovanka M. 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Many parasitic diseases are classified as neglected tropical diseases because they have received minimal funding over recent years and, in many cases, are under-reported despite the critical role they play in morbidity and mortality among human and animal hosts. The current topic, Parasitic Infectious Diseases, in the Infectious Diseases Series aims to publish studies on the systematics, epidemiology, molecular biology, genomics, pathogenesis, genetics, and clinical significance of parasitic diseases from blood borne to intestinal parasites as well as zoonotic parasites. We hope to cover all aspects of parasitic diseases to provide current and relevant research data on these very important diseases. In the current atmosphere of the Coronavirus pandemic, communities around the world, particularly those in different underdeveloped areas, are faced with the growing challenges of the high burden of parasitic diseases. At the same time, they are faced with the Covid-19 pandemic leading to what some authors have called potential syndemics that might worsen the outcome of such infections. Therefore, it is important to conduct studies that examine parasitic infections in the context of the coronavirus pandemic for the benefit of all communities to help foster more informed decisions for the betterment of human and animal health.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/5.jpg",keywords:"Blood Borne Parasites, Intestinal Parasites, Protozoa, Helminths, Arthropods, Water Born Parasites, Epidemiology, Molecular Biology, Systematics, Genomics, Proteomics, Ecology"},{id:"6",title:"Viral Infectious Diseases",scope:"The Viral Infectious Diseases Book Series aims to provide a comprehensive overview of recent research trends and discoveries in various viral infectious diseases emerging around the globe. The emergence of any viral disease is hard to anticipate, which often contributes to death. A viral disease can be defined as an infectious disease that has recently appeared within a population or exists in nature with the rapid expansion of incident or geographic range. 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Biochemistry examines macromolecules - proteins, nucleic acids, carbohydrates, and lipids – and their building blocks, structures, functions, and interactions. Much of biochemistry is devoted to enzymes, proteins that catalyze chemical reactions, enzyme structures, mechanisms of action and their roles within cells. Biochemistry also studies small signaling molecules, coenzymes, inhibitors, vitamins, and hormones, which play roles in life processes. Biochemical experimentation, besides coopting classical chemistry methods, e.g., chromatography, adopted new techniques, e.g., X-ray diffraction, electron microscopy, NMR, radioisotopes, and developed sophisticated microbial genetic tools, e.g., auxotroph mutants and their revertants, fermentation, etc. More recently, biochemistry embraced the ‘big data’ omics systems. Initial biochemical studies have been exclusively analytic: dissecting, purifying, and examining individual components of a biological system; in the apt words of Efraim Racker (1913 –1991), “Don’t waste clean thinking on dirty enzymes.” Today, however, biochemistry is becoming more agglomerative and comprehensive, setting out to integrate and describe entirely particular biological systems. The ‘big data’ metabolomics can define the complement of small molecules, e.g., in a soil or biofilm sample; proteomics can distinguish all the comprising proteins, e.g., serum; metagenomics can identify all the genes in a complex environment, e.g., the bovine rumen. This Biochemistry Series will address the current research on biomolecules and the emerging trends with great promise.",coverUrl:"https://cdn.intechopen.com/series/covers/11.jpg",latestPublicationDate:"May 18th, 2022",hasOnlineFirst:!0,numberOfOpenTopics:4,numberOfPublishedChapters:287,numberOfPublishedBooks:27,editor:{id:"31610",title:"Dr.",name:"Miroslav",middleName:null,surname:"Blumenberg",fullName:"Miroslav Blumenberg",profilePictureURL:"https://mts.intechopen.com/storage/users/31610/images/system/31610.jpg",biography:"Miroslav Blumenberg, Ph.D., was born in Subotica and received his BSc in Belgrade, Yugoslavia. He completed his Ph.D. at MIT in Organic Chemistry; he followed up his Ph.D. with two postdoctoral study periods at Stanford University. Since 1983, he has been a faculty member of the RO Perelman Department of Dermatology, NYU School of Medicine, where he is codirector of a training grant in cutaneous biology. Dr. Blumenberg’s research is focused on the epidermis, expression of keratin genes, transcription profiling, keratinocyte differentiation, inflammatory diseases and cancers, and most recently the effects of the microbiome on the skin. He has published more than 100 peer-reviewed research articles and graduated numerous Ph.D. and postdoctoral students.",institutionString:null,institution:{name:"New York University Langone Medical Center",institutionURL:null,country:{name:"United States of America"}}},subseries:[{id:"14",title:"Cell and Molecular Biology",keywords:"Omics (Transcriptomics; Proteomics; Metabolomics), Molecular Biology, Cell Biology, Signal Transduction and Regulation, Cell Growth and Differentiation, Apoptosis, Necroptosis, Ferroptosis, Autophagy, Cell Cycle, Macromolecules and Complexes, Gene Expression",scope:"The Cell and Molecular Biology topic within the IntechOpen Biochemistry Series aims to rapidly publish contributions on all aspects of cell and molecular biology, including aspects related to biochemical and genetic research (not only in humans but all living beings). We encourage the submission of manuscripts that provide novel and mechanistic insights that report significant advances in the fields. Topics include, but are not limited to: Advanced techniques of cellular and molecular biology (Molecular methodologies, imaging techniques, and bioinformatics); Biological activities at the molecular level; Biological processes of cell functions, cell division, senescence, maintenance, and cell death; Biomolecules interactions; Cancer; Cell biology; Chemical biology; Computational biology; Cytochemistry; Developmental biology; Disease mechanisms and therapeutics; DNA, and RNA metabolism; Gene functions, genetics, and genomics; Genetics; Immunology; Medical microbiology; Molecular biology; Molecular genetics; Molecular processes of cell and organelle dynamics; Neuroscience; Protein biosynthesis, degradation, and functions; Regulation of molecular interactions in a cell; Signalling networks and system biology; Structural biology; Virology and microbiology.",annualVolume:11410,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/14.jpg",editor:{id:"165627",title:"Dr.",name:"Rosa María",middleName:null,surname:"Martínez-Espinosa",fullName:"Rosa María Martínez-Espinosa",profilePictureURL:"https://mts.intechopen.com/storage/users/165627/images/system/165627.jpeg",institutionString:null,institution:{name:"University of Alicante",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"79367",title:"Dr.",name:"Ana Isabel",middleName:null,surname:"Flores",fullName:"Ana Isabel Flores",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRpIOQA0/Profile_Picture_1632418099564",institutionString:null,institution:{name:"Hospital Universitario 12 De Octubre",institutionURL:null,country:{name:"Spain"}}},{id:"328234",title:"Ph.D.",name:"Christian",middleName:null,surname:"Palavecino",fullName:"Christian Palavecino",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000030DhEhQAK/Profile_Picture_1628835318625",institutionString:null,institution:{name:"Central University of Chile",institutionURL:null,country:{name:"Chile"}}},{id:"186585",title:"Dr.",name:"Francisco Javier",middleName:null,surname:"Martin-Romero",fullName:"Francisco Javier Martin-Romero",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSB3HQAW/Profile_Picture_1631258137641",institutionString:null,institution:{name:"University of Extremadura",institutionURL:null,country:{name:"Spain"}}}]},{id:"15",title:"Chemical Biology",keywords:"Phenolic Compounds, Essential Oils, Modification of Biomolecules, Glycobiology, Combinatorial Chemistry, Therapeutic peptides, Enzyme Inhibitors",scope:"Chemical biology spans the fields of chemistry and biology involving the application of biological and chemical molecules and techniques. In recent years, the application of chemistry to biological molecules has gained significant interest in medicinal and pharmacological studies. This topic will be devoted to understanding the interplay between biomolecules and chemical compounds, their structure and function, and their potential applications in related fields. Being a part of the biochemistry discipline, the ideas and concepts that have emerged from Chemical Biology have affected other related areas. This topic will closely deal with all emerging trends in this discipline.",annualVolume:11411,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/15.jpg",editor:{id:"441442",title:"Dr.",name:"Şükrü",middleName:null,surname:"Beydemir",fullName:"Şükrü Beydemir",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003GsUoIQAV/Profile_Picture_1634557147521",institutionString:null,institution:{name:"Anadolu University",institutionURL:null,country:{name:"Turkey"}}},editorTwo:{id:"13652",title:"Prof.",name:"Deniz",middleName:null,surname:"Ekinci",fullName:"Deniz Ekinci",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYLT1QAO/Profile_Picture_1634557223079",institutionString:null,institution:{name:"Ondokuz Mayıs University",institutionURL:null,country:{name:"Turkey"}}},editorThree:null,editorialBoard:[{id:"241413",title:"Dr.",name:"Azhar",middleName:null,surname:"Rasul",fullName:"Azhar Rasul",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRT1oQAG/Profile_Picture_1635251978933",institutionString:null,institution:{name:"Government College University, Faisalabad",institutionURL:null,country:{name:"Pakistan"}}},{id:"178316",title:"Ph.D.",name:"Sergey",middleName:null,surname:"Sedykh",fullName:"Sergey Sedykh",profilePictureURL:"https://mts.intechopen.com/storage/users/178316/images/system/178316.jfif",institutionString:null,institution:{name:"Novosibirsk State University",institutionURL:null,country:{name:"Russia"}}}]},{id:"17",title:"Metabolism",keywords:"Biomolecules Metabolism, Energy Metabolism, Metabolic Pathways, Key Metabolic Enzymes, Metabolic Adaptation",scope:"Metabolism is frequently defined in biochemistry textbooks as the overall process that allows living systems to acquire and use the free energy they need for their vital functions or the chemical processes that occur within a living organism to maintain life. Behind these definitions are hidden all the aspects of normal and pathological functioning of all processes that the topic ‘Metabolism’ will cover within the Biochemistry Series. 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Thus proteomics, an area of research that detects all protein forms expressed in an organism, including splice isoforms and post-translational modifications, is more suitable than genomics for a comprehensive understanding of the biochemical processes that govern life. The most common proteomics applications are currently in the clinical field for the identification, in a variety of biological matrices, of biomarkers for diagnosis and therapeutic intervention of disorders. From the comparison of proteomic profiles of control and disease or different physiological states, which may emerge, changes in protein expression can provide new insights into the roles played by some proteins in human pathologies. Understanding how proteins function and interact with each other is another goal of proteomics that makes this approach even more intriguing. Specialized technology and expertise are required to assess the proteome of any biological sample. Currently, proteomics relies mainly on mass spectrometry (MS) combined with electrophoretic (1 or 2-DE-MS) and/or chromatographic techniques (LC-MS/MS). MS is an excellent tool that has gained popularity in proteomics because of its ability to gather a complex body of information such as cataloging protein expression, identifying protein modification sites, and defining protein interactions. The Proteomics topic aims to attract contributions on all aspects of MS-based proteomics that, by pushing the boundaries of MS capabilities, may address biological problems that have not been resolved yet.",annualVolume:11414,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/18.jpg",editor:{id:"200689",title:"Prof.",name:"Paolo",middleName:null,surname:"Iadarola",fullName:"Paolo Iadarola",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSCl8QAG/Profile_Picture_1623568118342",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorTwo:{id:"201414",title:"Dr.",name:"Simona",middleName:null,surname:"Viglio",fullName:"Simona Viglio",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRKDHQA4/Profile_Picture_1630402531487",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorThree:null,editorialBoard:[{id:"72288",title:"Dr.",name:"Arli Aditya",middleName:null,surname:"Parikesit",fullName:"Arli Aditya Parikesit",profilePictureURL:"https://mts.intechopen.com/storage/users/72288/images/system/72288.jpg",institutionString:null,institution:{name:"Indonesia International Institute for Life Sciences",institutionURL:null,country:{name:"Indonesia"}}},{id:"40928",title:"Dr.",name:"Cesar",middleName:null,surname:"Lopez-Camarillo",fullName:"Cesar Lopez-Camarillo",profilePictureURL:"https://mts.intechopen.com/storage/users/40928/images/3884_n.png",institutionString:null,institution:{name:"Universidad Autónoma de la Ciudad de México",institutionURL:null,country:{name:"Mexico"}}},{id:"81926",title:"Dr.",name:"Shymaa",middleName:null,surname:"Enany",fullName:"Shymaa Enany",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRqB9QAK/Profile_Picture_1626163237970",institutionString:null,institution:{name:"Suez Canal University",institutionURL:null,country:{name:"Egypt"}}}]}]}},libraryRecommendation:{success:null,errors:{},institutions:[]},route:{name:"chapter.detail",path:"/chapters/74294",hash:"",query:{},params:{id:"74294"},fullPath:"/chapters/74294",meta:{},from:{name:null,path:"/",hash:"",query:{},params:{},fullPath:"/",meta:{}}}},function(){var e;(e=document.currentScript||document.scripts[document.scripts.length-1]).parentNode.removeChild(e)}()