Summary of raster (bitmap) image file format.
\r\n\t2) Human sexual disorders in males and females.
\r\n\t3) Psychological aspects of the human sexual response cycle and its disorders.
\r\n\t4) The therapeutic aspects.
\r\n\tThe human sexual response cycle and human sexual behavior are interrelated. How this inter-relationship and its association to normal sexual health need to be delineated. In a world torn between sex and sexually transmitted disease, clear-cut scientific information in the form of a monograph is required to educate.
\r\n\r\n\tHuman sexuality, gender identity, and sexuo-erotic orientation play great roles in human health and disease. Sex education is the need of the hour and a reflection will be timely.
",isbn:"978-1-80355-151-7",printIsbn:"978-1-80355-150-0",pdfIsbn:"978-1-80355-152-4",doi:null,price:0,priceEur:0,priceUsd:0,slug:null,numberOfPages:0,isOpenForSubmission:!1,isSalesforceBook:!1,hash:"13af09c4cf93ae89789a3db597972cf6",bookSignature:"Dr. Dhastagir Sultan Sheriff",publishedDate:null,coverURL:"https://cdn.intechopen.com/books/images_new/11267.jpg",keywords:"Master and Johnson's Cycle, Sex Education, Premature Ejaculation, Orgasmic Disorders, Sexual Aversion Disorders, Dyspareunia, Vaginismus, Sex Hormones, Sexually Transmitted Diseases, Impotence, Low Libido, Blood Analyses",numberOfDownloads:99,numberOfWosCitations:0,numberOfCrossrefCitations:0,numberOfDimensionsCitations:0,numberOfTotalCitations:0,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"August 18th 2021",dateEndSecondStepPublish:"March 3rd 2022",dateEndThirdStepPublish:"May 2nd 2022",dateEndFourthStepPublish:"July 21st 2022",dateEndFifthStepPublish:"September 19th 2022",remainingDaysToSecondStep:"3 months",secondStepPassed:!0,currentStepOfPublishingProcess:4,editedByType:null,kuFlag:!1,biosketch:"Dr. Sheriff is a life counselor, sex educationist, and researcher with over 35 years of teaching experience, five authored books, and editorials written in the British Journal of Sexology and the Journal of Royal Society of Medicine. Dr. Sheriff is a life member of the European Society for Human Reproduction, and Early Human Development, American Association of Clinical Chemistry, Association of Physiologists and Pharmacologists of India, and a member of the National Academy of Medical Sciences.",coeditorOneBiosketch:null,coeditorTwoBiosketch:null,coeditorThreeBiosketch:null,coeditorFourBiosketch:null,coeditorFiveBiosketch:null,editors:[{id:"167875",title:"Dr.",name:"Dhastagir Sultan",middleName:null,surname:"Sheriff",slug:"dhastagir-sultan-sheriff",fullName:"Dhastagir Sultan Sheriff",profilePictureURL:"https://mts.intechopen.com/storage/users/167875/images/system/167875.jpg",biography:"Dhastagir Sultan Sheriff is a life member of the European Society for Human Reproduction and Early Human Development, Association of Physiologists and Pharmacologists of India, member of the National Academy of Medical Sciences, New Delhi, and resource person for UNESCO for Medical and Bioethics. 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From chapter submission and review to approval and revision, copyediting and design, until final publication, I work closely with authors and editors to ensure a simple and easy publishing process. I maintain constant and effective communication with authors, editors and reviewers, which allows for a level of personal support that enables contributors to fully commit and concentrate on the chapters they are writing, editing, or reviewing. I assist authors in the preparation of their full chapter submissions and track important deadlines and ensure they are met. I help to coordinate internal processes such as linguistic review, and monitor the technical aspects of the process. As an ASM I am also involved in the acquisition of editors. 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There has been a huge development in noninvasive medical imaging equipment. Since there are multiple medical equipment manufacturers, there is a strong need to develop a standard for storage and exchange of medical images. DICOM (Digital Imaging and Communications in Medicine) makes medical image exchange easier and independent of the imaging equipment manufacturer. The DICOM standard has been developed by ACR-NEMA to meet the needs of manufacturers and users of medical imaging equipment for interconnection of devices on standard networks. The DICOM technology is suitable when sending images between different departments within hospitals and/or other hospitals and the consultant. DICOM file contains both a header, which include text information such as patient’s name, modality, image size, etc., and image data in the same file. Hence DICOM standards are widely used in the integration of digital imaging systems in medicine. \nFigure 1\n shows the structure of DICOM image file. It has two main components. The first is header; it consists of 128 bytes of file preamble which is followed by string by 4-byte prefix, and it contains four-character string. The second is data set; it consists of multiple set of data elements. Each data element has four fields; these are tag, value representation, value length, and value field. The third is image pixel intensity data; it contains necessary medical image data display like number of frames, lines, columns, etc.
\nThe structure of a DICOM image file.
There are four major file formats in medical imaging, and they are Neuroimaging Informatics Technology Initiative (NIfTI), Analyze, DICOM, and MINC. The task of the image file format is to provide a standardized way to store the unique data in a much organized and systematic manner and showcase how the pixel data understood the correct loading, visualization, and analysis was derived by the software. The major file format currently useful in medical imaging is DICOM format. The DICOM format includes some information that can be useful for image registration, such as position and orientation of the image with respect to the data acquisition device and patient information with respect to voxel size. DICOM file format design consideration is based on the following concept such as pixel depth, photometric interpretation, metadata, and pixel data. The DICOM file format is created by addition of header size and pixel data. Mathematical equations are as follows:
\nThe more popular formats used in daily practice are the JPEG, JPEG 2000, TIFF, GIF, PNG, and BMP formats. The images saved in these formats can be accessed on any personal computer without the need of specific viewers. File format are designed with the help of image conversion technique and coding schemes.
\nThe rest of the chapter is organized as follows. Section 2 provides an overview of image file format and image standard used for medical image compression, and data hiding methods are described in the Section 3. Section 4 provides proposed work brief explanation. Section 5 discusses regarding results that are obtained after implementation of application. Finally, Section 6 concludes the chapter.
\nThe related work is a comprehensive summery of previous research on image file format, standard image compression using transform coding, and patient information integration into image for DICOM images. The more popular formats used in daily practice are the JPEG, JPEG 2000, TIFF, GIF, PNG, and BMP formats. The images saved in these formats can be accessed on any personal computer without the need of specific viewers. File formats are designed with the help of image conversion technique and coding schemes [1, 2, 3]. \nFigure 2\n shows the basic digital image file formats and its classification. The vector images are not commonly used in medical data processing.
\nBasic digital classification image file format.
\n\nTable 1\n gives the summary of various parameters of raster image file format [4, 5, 7, 8, 9, 10, 11]. \nTable 2\n gives a characteristic overview of the major file formats currently used in medical imaging, i.e., NIfTI, Analyze, DICOM, and MINC [6, 12, 13].
\nSr. no. | \nFile format | \nExtension | \nBit depth | \nCompression type | \nCompression performance | \nName of supported free image viewer | \n|
---|---|---|---|---|---|---|---|
\n | \n | \n | Gray | \nColor | \n\n | \n | \n |
1 | \nBMP | \nbmp | \n1,4,8 | \n1,4,8,24 | \nLossless | \nVery low | \nIrfanView, XnView, Osiris, ImageJ | \n
2 | \nDICOM | \ndcm | \n8, 16 | \n8, 24, 48 | \nLossless | \nLow | \nIrfanView, XnView, Osiris, ImageJ | \n
3 | \nGIF | \ngif | \n1, 4, 8 | \n1, 4, 8 | \nLossless | \nMedium | \nIrfanView, XnView, Osiris, ImageJ | \n
4 | \nJPEG | \njpg | \n8 | \n24 | \nLossy | \nAverage | \nIrfanView, XnView, Osiris, ImageJ | \n
5 | \nJPEG 2000 | \nJp2 | \n8, 16 | \n24, 48 | \nLossless | \nHigh | \nIrfanView, XnView | \n
6 | \nPNG | \npng | \n1, 4, 8, 16 | \n1, 4, 8, 24, 48 | \nLossless | \nHigh | \nIrfanView, XnView | \n
7 | \nTIFF | \ntiff | \n8, 16 | \n8, 24, 48 | \nLossless or lossy | \nVery high | \nIrfanView, XnView | \n
Summary of raster (bitmap) image file format.
Sr. no. | \nFile format | \nExtension | \nData type | \nHeader | \nCompression scheme supported | \n||
---|---|---|---|---|---|---|---|
\n | \n | \n | Integer | \nFloat | \nComplex | \n\n | \n |
1 | \nDICOM | \n.dcm | \nSigned and unsigned (8 bit, 16 bit, 32 bit) | \nNot supported | \nNot supported | \nVariable length binary format | \nJPEG, RLE, JPEG-LS, MPEG2/MPEG4, JPEG XR | \n
2 | \nNIfTI | \n.nii | \nSigned and unsigned (8 bit to 64 bit) | \nSigned and unsigned (32 bit to 128 bit) | \nSigned and unsigned (64 bit to 256 bit) | \nFixed length (532 byte binary format) | \ngzip (it is a software application used to store compressed and decompressed file) | \n
3 | \nMINC | \n.mnc | \nSigned and unsigned (8 bit to 32 bit) | \nSigned and unsigned (32 bit to 64 bit) | \nSigned and unsigned (32 bit to 64 bit) | \nExtended binary format | \ngzip (it is a software application used to store compressed and decompressed file) | \n
4 | \nAnalyze | \n.hdr and .img | \nSigned (8 bit to 32 bit) and unsigned (8 bit) | \nSigned (32 bit to 64 bit) | \nSigned (64 bit) | \nFixed length (348 byte binary format) | \nHigh dynamic range (HDR) imaging uses sub-band coding technique which is an example of lossy technique | \n
Characteristics of medical image file format.
Two types of compression methods are classified. The lossless image has huge application in archival of medical and digital radiography document, where loss of information in original image could consider improper diagnosis. The medical imaging application required lossless image compression. Thus, medical image compression application development is a challenging problem. The survey paper [14] conveys that compression ratio 4:1 is possible using lossless compression. An increasing volume of data generated by new imaging modality, CT scan and MRI lossy compression technique are used to decrease the cost of storage and increase the efficiency of transmission over networks for teleradiology application [12]. There are two main categories of compression lossless (reversible) and lossy (irreversible). DICOM support lossless compression schemes like run-length encoding, Huffman coding, LZW coding, area coding, and arithmetic coding. The RLE is used for medical image compression in hybrid approach, where gray scale value gives certain interesting fact about the distribution in image. The background pixels of all the medical image are low values, and they differ by +3 or −3. The RLE is based on dynamic array implementation, no need to process whole image [8]. The paper served that the number of repeated zero count which is represented as “RUN” and appends the nonzero coefficients represented as “LEVEL” [15, 16]. The Huffman coding is a lossless compression technique, which is used for medical image compression. This works on variable length encoding principal, which includes calculation of length of unique codes. It generates a binary tree, which is also known as Huffman tree. Huffman algorithm gives higher compression ratio in the case of medical image compression. During the whole process of compression, there should not be any loss of information that will affect proper diagnosis [17, 18]. The Huffman code is designed to integrate the lowest probable symbols, and this integration is repeated until only two probabilities of two symbols are left. In this survey paper, certain improvements are discussed on the existing Huffman technique which will help to preserve any loss of information during compression that will affect proper diagnosis [19]. In lossy compression method, data are rejected during compression and cannot be recovered completely. This method reaches much greater compression performance than lossless compression. Wavelet and higher-level JPEG are the example of lossy compression technique where JPEG 2000 is a progressive lossless-to-lossy compression algorithm [20, 21, 22]. This article uses the concept of data hiding into image for data encryption. In order to enable large capacity of data hiding and maintaining good image quality, the data integration is applied on detail coefficients of high-frequency sub-bands. It works on transform domain of multilevel two-dimensional discrete wavelet transform. The objective of this implementation is to perform image compression as much as possible. It will help to reduce the redundancy of the image and to store or transmit data in an efficient form. As in telemedicine, the medical images are transmitted through advanced hyperlinks; medical image compression without any loss of useful information is of immense importance for the fast transfer of the medical data [23].
\nThis proposed compression approach deals with .dcm file of DICOM format. It splits .dcm file into patient data with bmp.txt extension and gray scale image with .bmp extension. Then N-level DWT using various wavelet types is applied to a gray image. Firstly, this splits the image into n number of high-frequency sub-bands (HLn, LHn, HHn) where n = 1, 2, 3…..N and one low-frequency sub-band (LLn) where n = maximum level (N). The high-frequency sub-bands at levels 1, 2, 3, and 4 are threshold and quantized and find detail coefficients are encoded directly through run-length encoding. Secondly, the one low-frequency sub-band is also threshold and quantized and find high-level approximate coefficient. Lastly, both the coefficients (detail coefficients, high-level approximate coefficient) are encoded by Huffman coding.
\nIn a gray scale image, each pixel is represented by 8-bit unsigned integer value. The minimum and maximum value of unsigned integer is 0 to 255. The 0 represented black and 255 represent white. In text file every text file is represented by ASCII value. The ASCII value is run between 0 and 128. The extended ASCII value is 8 bit, and it matched with 8-bit pixel intensity. So, both the entities are treated as normal integer. In this proposed system, we have practiced bitwise XOR approach for text integration into image. The proposed work deals ASCII conversion of patient data and multilevel two-dimensional discrete wavelet transform. Advantages of this work are high data integrity even with large patient data. Accepted levels of imperceptibility, excellent PSNR values, and high CR and good payload capacity are obtained. \nFigures 3\n and \n4\n represented the block diagram of compression and decompression with data integration scheme. The decompression process is the inverse process of DICOM image compression as shown in block diagram in \nFigure 4\n. The DICOM compressed image is recreated with acceptable quality through the abovementioned process.
\nBlock diagram of DICOM image compression and data integration method.
Block diagram of DICOM image decompression and data and image extraction.
\n
Select a proper Greyscale BMP image.
Select patient text file with .txt extension
Execute while loop (Number of Character Count in text file<= Number of pixels in the image)
Convert Character vector and pixel value into an unsigned 16-bit integer using function str2num and unit 16.
Integration of text in to Image Pixel = (Converted 16-bit unsigned pixel value) XORing_Bitwise (Converted 16-bit unsigned character value)
Increment Pixel value until last value.
Increment Character value until last value
Check the Character Count in text file = Character Count +1
End Loop
Rest of Integration of text in Image Pixel = original pixels of image
\n
Open the original image and Integration of text in to Image Pixel
Execute while loop (Number of Pixel Count in image file ≤ Number of pixels in the image)
Convert pixel value into 16-bit integer value
Integration of text in to Image Pixel = convert to 16-bit integer (Integration of text in to Image Pixel)
A = (Original value of Pixel) XORing_Bitwise (Integration of text in to Image Pixel)
if A = 0 then break, else extracted text file which is equal to A
Extract original Pixel = Next original Pixel in image
Integration of text in to Image Pixel = Next Integration of text in to Image Pixel
End Loop
We implement an N-level 2D DWT decomposition. At each level of decomposition, the LL sub-band from the previous level is obtained, and each previous level is replaced with four new sub-bands. Each new sub-band is half the width and half the height of the LL sub-band from its parent sub-bands. The formula to calculate the total number of sub-bands depends on the number of level n. The number of sub-bands is therefore 3n + 1, where HHn represent high-frequency band, LLn is low-frequency band, and LHn and HLn are middle-frequency bands. The coefficients in LL are dominant. If any of the coefficients in LLn frequency band are changed, observer can observe that the corresponding spatial domain image has been modified.
\n\n\nFigure 5\n shows the process of character integration in LHn sub-band, and it generates wavelet coefficients. It shows the scale and orientation selectivity of the DWT. Greatest energy is contained in the LLn sub-band, and the least energy is in the HHn sub-band. The HLn sub-band contains the vertical edges, and the LHn sub-band contains the horizontal edges. In this proposed work, we focus on data integration in LHn sub-bands because this band has high energy distribution as compared to other bands like HLn and HHn. The finest wavelet type and the appropriate coefficient selection method using threshold and quantization.
\nThe process of character integration in LHn sub-bands and generation of wavelet coefficients.
Let n × n be matrix of an original image; noise observation can be written as \n
If
\nwhere y (i) is the input and noise wavelet coefficients, λ is the Threshold Valu, \n
We define the PCDZ parameter; this parameter is required to calculate the percentage of nonzero DWT coefficients.
\nwhere NBz = number of zeros in DWT coefficients.
\nLy = Number of Coefficients in DWT.
\nThe proposed method used in the global threshold value that is derived by Donoho [19, 20] is given by the equation below. It is known to have a universal threshold.
\nwhere Ly is the number of pixels in the medical image and σ is the noise variance.
\nThe quantization of each level permits to collect the set of nearest values. The uniform quantization on thresholded DWT coefficients in sub-bands will be transformed and to be contained in the interval width for quantization is between 0\n
In this implementation, hierarchical relationship of wavelet structure is explored to arrange wavelet coefficients into odd rows and even rows. The wavelet coefficients odd rows contain an ordering of wavelet coefficient that acts as approximate (smooth) value, and even rows contain different sign data that act as detail values. After evaluated many zeros in different orders of wavelets, by applying hard thresholding condition Eqs. (4), (5) on wavelet coefficients. In this whole process, separated approximate coefficients contain best information, while detail coefficients contain information like shapes and edges of image. The threshold condition chooses fixed threshold value to obtain desired quality of reconstructed image. After classifying threshold coefficients, need to transmit those coefficients using lossless method which will further be used for decompression purpose. Now encoded detail coefficients with run-length encoding excluding the highest approximate coefficient LL3 sub-bands, because LL3 sub-band does not have much long run of zeros. To convert repetitive data into bit stream, Huffman encoder has been used in this implementation. Huffman code is an example of optimum prefix code; these codes are generated using variable code length where a number of bits are essential. This will be helpful in average code length calculations, and thus the data compression is taking place where sometimes compressed image is smaller than original image.
\nThe performances of implemented method are based on few essential criteria: the obtained compression ratio (CR), compression gain, and the quality of the reconstructed image using PSNR, MSE (mean squared error), and SNR. Data compression equations are given below.
\nData compression ratio = Uncompressed size/Compressed size
\nSpace saving (%) determines performance of transformation efficiency over storage of data bits for original bit size to unprocessed bit size. It is like compression ratio; however it reflects percentage of how much data space is saved following compression [21]. It is given by the following equation:
\nPercentage of Compression Gain = 1 – Compressed size/Uncompressed Size
\nThe calculated peak signal to noise ratio between maximum values is power of signal and power of distorting noise which affects the quality of its representation. The PSNR is generally expressed in terms of logarithmic decibel scale [22].
\n\n\n
where the MSE
\nwhere f is the matrix data of our original image. g is the matrix data of our degraded image. m is the numbers of rows of pixels of the images. i is the index of that row. n is the number of columns of pixels of the image. j is the index of that column.
\nwhere SNR is given as the ratio of the mean value of the signal and the standard deviation of the noise.
\nTo analyze the performance of our proposed method, we take \nTable 3\n as an input MR image for evaluation of various parameters, and their information are as follows:
\nImage name | \nInput size (in KB) | \nLevel of decomposition (N) | \nNoise variance (\n | \nThe size of the DWT coefficient arrays (Ly) | \nThreshold value (\n | \n
---|---|---|---|---|---|
1.2.840.113619.2.5.1762583153.215519.978957063.122.dcm | \n522 | \n3,4 | \nσ = 1 | \n266,539 | \n3.29416477 | \n
Input MR image for evaluation of various parameters.
\n\nFigure 6\n shows that pop-up message is generated after compression of DICOM input image, and it displayed warning dialog that image is compressed successfully, and then after pressing the ok button, compressed image is stored in image folder with. Hdwt extension (\nFigure 7\n).
\nGraphical user interface of DICOM image 1.2.840.113619.2.5.1762583153.215519.978957063.122.dcm of 522 KB for N = 3 and after pressing pop-up button of image compression successfully with size.
Graphical user interface of DICOM image 1.2.840.113619.2.5.1762583153.215519.978957063.122.dcm of 522 KB for N = 4 has displayed PSNR, MSE, and SNR parameters after pressing pop-up button of decompression.
\n\nFigure 8\n shows that if input image size is 522 KB, then Biorthogonal DWT give highest compressed size, and Reverse Biorthogonal DWT gives lowest compressed size. The decomposition level = 4 gives better result than N = 3.
\nThe plot for size of compressed image in KB vs wavelet types for N = 3 and 4.
\n\nFigure 9\n plot shows comparison of compression ratio when decomposition level is 3 or 4 for various wavelet types where size of input MRI is 522 KB. Biorthogonal DWT gives higher compression ratio, and Discrete Meyer DWT and Reverse Biorthogonal DWT give lower compression size. N = 4 gives better compression ratio (15:1 for Biorthogonal DWT and 10:1 Daubechies DWT) than N = 3.
\nThe plot for compression ratio vs wavelet types For image size of input(MRI) image size 522 KB, when N = 3 and 4 compare.
In \nFigure 10\n, figure graph shows comparison of compression gain when decomposition level is 3 or 4 for various wavelet types where size of input MRI is 522 KB. Biorthogonal DWT gives higher compression gain, and Discrete Meyer DWT and Reverse Biorthogonal DWT give lower compression gain. N = 4 gives better compression gain (93.6781% for Biorthogonal DWT and 90.6130% for Daubechies DWT) than N = 3 (\nFigure 11\n).
\nThe plot for compression gain vs wavelet types where image size of input (MRI) image size 522 KB for N = 3 and 4.
The 36 KB of input .dcm file, compressed HDWT file, text file, and patient data integrated into the image file for Biorthogonal DWT.
\n\nTable 4\n shows comparison of image quality parameters when application run at decomposition levels 3 and 4 for various wavelet types where size of input MRI is 522 KB. Daubechies DWT gives higher PSNR (42.0998db) where MSE is (35.2626db) and SNR is (28.3993 db). So, picture quality is good for N = 3. When we consider N = 4 decomposition level, we can choose Daubechies DWT for compression to achieve higher quality of medical image. This tool does not work on Haar DWT; there is no output for Haar wavelet type.
\nInitial size of image: 522 KB (image name: 1.2.840.113619.2.5.1762583153.215519.978957063.122.dcm) | \nImage quality parameter for N = 3 (in decibels) | \nImage quality parameter for N = 4 (in decibels) | \n||||
---|---|---|---|---|---|---|
Wavelet types | \nPSNR | \nMSE | \nSNR | \nPSNR | \nMSE | \nSNR | \n
Biorthogonal DWT | \n35.3358 | \n35.2626 | \n21.6352 | \n30.7777 | \n35.3626 | \n17.0771 | \n
Haar DWT | \n\n | \n | \n | \n | \n | \n |
Daubechies DWT | \n42.0998 | \n35.2626 | \n28.3993 | \n39.6729 | \n35.3626 | \n25.9723 | \n
Symlets DWT | \n39.0696 | \n35.3626 | \n25.3691 | \n36.6956 | \n35.3626 | \n22.995 | \n
Coiflets DWT | \n40.4769 | \n35.3626 | \n26.7763 | \n36.1026 | \n35.3626 | \n22.402 | \n
Reverse Biorthogonal DWT | \n32.0256 | \n35.3626 | \n18.325 | \n26.3603 | \n35.3626 | \n12.6597 | \n
Discrete Meyer DWT | \n40.6572 | \n35.3626 | \n26.9566 | \n32.5428 | \n35.3626 | \n18.8423 | \n
Input MRI .dcm file input having 522 KB size for evaluation of various image quality parameters.
\n\nTable 5\n indicates that Daubechies, Symlets, and Coiflets DWT give higher compressed image size (9 KB) and highest compression ratio (4) and gain (75%). Decompression is working in this input size (36 KB). So, when the small-size input .dcm file, image reconstruction is required, this implementation work will be applicable. This application gives good PSNR (45.1486) and better MSE (29.88) and SNR (30.0124) for Daubechies DWT.
\nSr. no. | \nWavelet type | \nSize of compressed image (in KB) | \nCR | \n% of CG | \nPSNR (in db) | \nMSE (in db) | \nSNR (in db) | \n
---|---|---|---|---|---|---|---|
1 | \nBiorthogonal DWT | \n15 | \n2.4 | \n58.33333 | \n35.2407 | \n19.9722 | \n39.0124 | \n
2 | \nHaar DWT | \n11 | \n3.272727 | \n69.44444 | \n44.8457 | \n29.5771 | \n30.0124 | \n
3 | \nDaubechies DWT | \n9 | \n4 | \n75 | \n45.1486 | \n29.88 | \n30.0124 | \n
4 | \nSymlets DWT | \n9 | \n4 | \n75 | \n44.9406 | \n29.6721 | \n39.0124 | \n
5 | \nCoiflets DWT | \n9 | \n4 | \n75 | \n38.9493 | \n23.6808 | \n39.0124 | \n
6 | \nReverse Biorthogonal DWT | \n18 | \n2 | \n50 | \n35.7811 | \n20.5126 | \n39.0124 | \n
7 | \nDiscrete Meyer DWT | \n15 | \n2.4 | \n58.33333 | \n44.6503 | \n29.3818 | \n39.0124 | \n
Compression and image quality performance of input (CT scan) image size 36 KB for different wavelet types.
\n\nTable 6\n indicates that Biorthogonal DWT gives higher compressed image size (2 KB) and highest compression ratio (18:1) for threshold value = 50. But image quality is degraded due to PSNR value = 32.7496.
\nParameters | \nλ =3 | \nλ =10 | \nλ = 20 | \nλ = 30 | \nλ = 50 | \n
---|---|---|---|---|---|
Compressed image in KB | \n9 | \n5 | \n4 | \n3 | \n2 | \n
Compression ratio | \n4 | \n7.2 | \n9 | \n12 | \n18 | \n
PSNR | \n35.1707 | \n34.5081 | \n33.673 | \n33.1783 | \n32.7496 | \n
MSE | \n19.9022 | \n19.2396 | \n18.4 | \n17.9098 | \n17.9098 | \n
SNR | \n39.0124 | \n39.0124 | \n39.0124 | \n39.0124 | \n39.0124 | \n
Compression and image quality performance of input (CT scan) image size 36 KB (gray scale) for different threshold values on Biorthogonal DWT using proposed method.
\n\nTable 7\n shows that CT0081 gives good compression result for implemented method, but other input CT images give less compression ratio than .jpg file format. The obtained result shows that.
\nSr. no. | \nImage ID | \nDimension | \nDepth in bit | \nInput file size in KB | \nDICOM size in KB | \n.jpg file size in KB | \nImplemented method .hdwt size in KB | \n
---|---|---|---|---|---|---|---|
1 | \nCT0014 | \n512 × 512 | \n24 | \n1030 | \n769 | \n25 | \n29 | \n
2 | \nCT0051 | \n512 × 200 | \n24 | \n204 | \n301 | \n17 | \n22 | \n
3 | \nCT0052 | \n250 × 512 | \n24 | \n254 | \n376 | \n17 | \n26 | \n
4 | \nCT0059 | \n350 × 512 | \n24 | \n353 | \n526 | \n23 | \n46 | \n
5 | \nCT0074 | \n512 × 512 | \n24 | \n5130 | \n769 | \n61 | \n67 | \n
6 | \nCT0081 | \n888 × 733 | \n24 | \n2547 | \n1908 | \n167 | \n165 | \n
7 | \nCT0090 | \n512 × 512 | \n24 | \n3591 | \n769 | \n93 | \n152 | \n
8 | \nCT0101 | \n512 × 512 | \n24 | \n516 | \n769 | \n92 | \n71 | \n
9 | \nCT102 | \n512 × 605 | \n24 | \n609 | \n909 | \n153 | \n162 | \n
10 | \nCT110 | \n512 × 512 | \n24 | \n4616 | \n769 | \n61 | \n68 | \n
Comparison of implemented method and .JPG format for 10 CT scan DICOM images.
Compression and decompression are necessary tasks in medical imaging applications. This implementation provides patient data integration within the medical image. It is very important to maintain the patient data security. This implementation work is very helpful to hide and recover patient information within the medical image and follow compression/decompression without any data loss. In this implanted work, 2D DWT and N-level decomposition are applied on medical image, and then the extracted detail coefficients are firstly encoded by RLE. Secondly, the extracted approximate coefficient and encoded detailed coefficients are encoded by Huffman encoder. The generated result shown that Biorthogonal DWT gives better compression size, compression ratio, and compression gain for higher decomposition level (N = 4), but image quality parameters like PSNR and MSE are degraded. After comparison with JPEG file format and implemented work, this work gives less compression size. We conclude that for medical image compression, we can select N = 3, decomposition level with λ = 3, threshold value, and Biorthogonal DWT for good image quality.
\nAuthors thank Dr. S.V. Dudal, HOD, Department of Applied Electronics, SGBA University, Amravati, India, for providing all kind of facilities and support.
\nThe authors declare that there is no conflict of interests, financial, potential, or otherwise associated with this manuscript.
3D printing is an additive manufacturing (AM) process that enables the manufacturing of components with complex geometries in a layer-by-layer fashion. 3D printing became popular after the first machine was introduced to the market in 1986 by Hull [1]. Charles Hull created the first stereolithography (SLA) manufacturing method which he used for the rapid design and manufacturing of small prototype plastic parts. Stereolithography uses light to activate polymers within a resin (photopolymerization) to create 3D, complex shapes [2, 3]. This SLA system was commercialized in 1987 by the company 3D Systems. Since this breakthrough invention, there has been great effort in producing machines that can process a variety of plastics. Some of the machines currently in the market are fused deposition modeling (FDM) [4, 5] and direct ink write (DIW) for extrusion-based processes [6, 7]. Powder bed fusion (PBF) and laser sintering (SLS) are used for processes requiring a laser to cure or fuse polymeric materials [8]. Inkjet printers also use light to photopolymerize ink drops into complex shapes [9]. Extensive reviews on these processing and 3D printing technologies have been published elsewhere [4, 5, 10, 11, 12, 13, 14]. This chapter focuses on applications that use AM for the 3D printing of polymeric materials.
\nSince the 1980s, 3D printing has become very popular as a result of the rapid manufacturing of components with architectures designed to meet specific applications. AM allows for the manufacturing of a variety of shapes in a layer-by-layer fashion, often without the need of post-processing such as machining. As a general scheme, AM starts with the design of a virtual object using CAD (computer-aided design) software that generates a STL (stereolithography, named after Charles Hull’s SLA process) file format [15]. A slicer program interprets the STL file and converts it into g-code (e.g. Slic3r, 3DPrinterOS, MakerBot Print, and others). The computer controls the stage and dispenser of the 3D printer allowing prototypes to be manufactured. Rapid prototyping allows one to refine product ideas while saving significant time and money because it allows for iterations prior to creating a final product. Optimization via an iterative process involves touching and feeling the prototype, in real time, in order to finalize the shape and geometry, leading to a final product. Characterization methods during iterations and on the final design include optical microscopy, SEM, and mechanical tests. Others methods, such as bio-compatibility (cell-adhesion and proliferation) and electrical performance are performed depending on the application. Figure 1 demonstrates a general scheme for the AM process. Despite the many advances in AM, the technology still has many challenges that need to be addressed. These challenges are related to the speed of the processes (which in many cases is slower than injection molding processes and machining), cost of the machines, and limited feedstock. However, advantages outweigh the challenges due to the fact that AM allows for compositional flexibility, complex macro and microstructures, and easy modeling and optimization. As a result, industries including biomedical engineering, transportation, and the military have adopted AM as the main manufacturing method for the printing of prototypes and final parts [16, 17].
\nGeneral scheme for the use of additive manufacturing processes, from the choice of material to the final product. The 3D printing of parts involves the use of a computer-assisted design software that generates a STL file format that is then sliced and formatted into gcode. The computer controls the stage and dispenser to generate materials with specific architectures, e.g. faced-centered tetragonal cushion using direct ink writing (a) and diamond structure using FDM (b).
Careful attention is imperative when choosing a material to print a given part. While there are a variety of commercially available polymers, not one polymer is inclusive and will give one the properties needed for a specific application. Furthermore, a single AM technique is not capable of printing any one individual polymer available in the market. The selection of material depends on the application and the customers’ needs. Figure 2 lists the decision criteria for the selection of a material. One must take into consideration the environment at which the part will be exposed and the properties required (e.g. temperature, mechanical load, humidity, chemical exposure, radiation, UV light), the processability, 3D printing method, and availability.
\nMaterial selection chart for product design and manufacturing.
Polymers have become consumer goods, for they are used to manufacture bottles, toys, tools, bags, phones, computers, tools, cushions, electronics and transportation components [18]. Thus, it makes sense that efforts have focused on developing materials that can be 3D printed, which allows for rapid manufacturing [2, 3, 4, 17]. Table 1 lists commercially available polymers used in some of the AM processes. Polycarbonate (PC), acrylonitrile butadiene styrene (ABS), poly ether ester ketone (PEEK), polyetherimide (ULTEM) and Nylon are common polymers used in processes requiring thermoplastics, or plastics that are processed by heating to a semi-liquid state and close to the melting point. Upon extrusion, the printed layers fuse and solidify. AM techniques that use thermoplastics are Fused-Deposition Modeling (FDM), Jetting (InkJet), and Selective Laser Sintering (SLS). SLA and Direct Ink Writing (DIW) use thermosetting polymers in their liquid state, or polymers that become solids after curing. A chemical reaction occurs prior to the melting point, resulting in a solid-state material. In SLA and DIW, polymers are formulated to meet specific properties, most importantly rheological. For example, each layer should be self-supporting and should allow for the printing of multiple layers while retaining the designed geometry [14, 19, 20, 21]. Rheologically, this corresponds to a resin that has a yield stress at high oscillatory stresses, such that the resin is solid-like at rest (low stress) and liquid like during flow (high stress) [7]. One of the main challenges in the polymer 3D printing industry is the limited feedstock available for purchase. Polymers listed in Table 1 cannot be used in all applications. Particularly, polymers in the pure state lack mechanical strength for load-bearing applications. The addition of fillers, such as silica [22, 23] and carbon fibers [24, 25], is often used to generate materials with high mechanical strength. Furthermore, the incorporation of additives enhances materials properties by adding functionality to the parts that include getter [20], UV and radiation resistance [26, 27, 28], and anti-fouling properties [29, 30, 31].
\nAM technology | \nProcess | \nPhysical state of starting material | \nFeedstock | \n
---|---|---|---|
FDM | \nMelting-solidifying | \nSolid | \nPC, ABS, PLA, ULTEM, Nylon, Carbon-filled Nylon, ASA | \n
SLA | \nPhotocuring | \nLiquid | \nThermosetting- acrylates and epoxy | \n
SLS | \nMelting-solidifying | \nSolid | \nPCL, PLA | \n
Jetting | \nPhotocuring | \nSolid | \nABS, ASA, PCL, PLA, Vero | \n
Direct Writing | \nExtrusion-heat/UV curing | \nliquid | \nThermosetting- any material with adequate viscosity | \n
List of polymers used for 3D printing applications.
The biomedical market represents 11% of the total AM market share today, and will be a strong driver for AM development and growth [32]. Since the early 2000s, there has been increased interest in using 3D printing to fabricate hard tissues (bones, teeth, cartilage) and soft tissues (organs, skin, and others) [2, 3, 4, 16, 33]. The manufacturing of prostheses and scaffolds with complex geometries is especially important for regenerative medicine, where a porous scaffold is implanted into the patient to serve as a template for tissue to regenerate while the implant degrades slowly in the body. Other implants need to stay in place for the lifetime of the patient. 3D printing allows for the rapid manufacturing of customized prosthetics and implants with controlled architectures. The structure can be designed through the translation of x-ray, MRI, and CT images into STL file formats. The STL file can be processed by software and a design can be generated based on the patient’s specific needs. Metals are commonly used to generate prosthetics for bone reconstruction. ABS and PLA are the most suitable non-biodegradable polymers used for the manufacturing of scaffolds. However, materials used in medicine must enable cell adhesion, growth, and differentiation. Current feedstock for biomaterials is limited to collagen, gelatin, fibrin, and chitosan, which are similar to natural tissue, have high affinity to cells and are highly hydrated. The main challenge with these soft natural polymers is their low mechanical strength [33]. In biomedical engineering, the main focus has been on the development of biopolymeric materials for tissue and scaffold generations with improved flexibility, strength, and patient compatibility in order to prevent implant rejection and toxicity. Some polymeric mixtures include living cells isolated from the patient and grown in the laboratory. These types of polymers are often hydrogels suitable for ink jet 3D printing technologies. Table 2 shows various polymers used for biomedical applications. Some examples of biomedical devices developed using 3D printing are implants, prosthetics, dental, orthodontics, hearing aids, and drug release tissues.
\nMaterial | \n3D printing techniques | \nComments | \n
---|---|---|
PLA, PCLA, PLGA | \nFDM | \nScaffolds. Biodegradable. Can add fillers, e.g. HA, for improved cell adhesion and mechanical properties | \n
Collagen, alginate, PEG, fibrin, chitosan | \nInkjet, extrusion | \nBiodegradable scaffolds. Can add fillers and cells for improved cell adhesion and mechanical properties | \n
PCL, methacrylate copolymers | \nSLS | \nBiodegradable scaffolds. Improved mechanical properties | \n
Polymers and processes used for the additive manufacturing of biomedical devices.
Polymers used for tissue and organ fabrication need to have various functions in order to (1) allow for cell attachment and migration, (2) transfer growth factors and waste products, (3) maintain its shape while cells are growing and (4) maintain adequate mechanical properties. Wu et al. [34] reported the generation of a biopolymeric material based on chitosan dissolved in an acid mixture of acetic acid, lactic acid, and citric acid. This biomaterial was 3D printed using an ink-writing technique, then dried under vacuum and neutralized to remove any acid residue. The structure of the scaffold was characterized using confocal laser scanning microscopy and the images showed wrinkles attributed to the volume change. Tensile mechanical tests show that the printed material exhibits a strain to failure of 400% under tensile load and a 7.5 MPa ultimate strength when in its neutralized form. Furthermore, the 3D printed material allows for excellent cell adhesion, growth, and proliferation, as demonstrated using the Live-Dead staining method, fluorescence microscopy, and SEM.
\nLuo et al. [35] reported the 3D printing of a bioceramic hollow struts-packed scaffold using an extrusion typ. 3D printer and a shell/core nozzle. The ink contained Ca7Si2P2O16, alginate and Pluronic F-127. After printing, the ink was dried overnight and sintered for 3 hours at 1400°C to remove the alginate and F-127 materials. The morphology was analyzed using an optical microscope. The micropores and the microstructure of the pores were characterized using SEM. The fabricated scaffolds (16/23 shell/core size) were subjected to mechanical testing and exhibited a compressive strength of 5 MPa, comparable to cancellous bone (2–12 MPa), and a modulus of 160 MPa. The scaffold had high porosity (65–85%), adjusted with the core/shell size nozzles. The high porosity and surface area (up to 6500 mm2/g) allowed for cell adhesion and proliferation on the outer and inner surface of the scaffold, as determined by SEM. Finally, the in-vivo bone formation study in a rabbit demonstrated that the bioceramic implant allows for good cell integration and bone formation was detected with micro-CT.
\nLewis’ team at Harvard University 3D printed a tympanic membrane scaffold composed of PDMS, PLA, and PCL based materials using a DIW technique [36]. The team demonstrated that it is possible to design and fabricate materials with similar properties when compared to human specimens. The high frequency displacement and acoustics were organized by concentric rings for each 3D printed graft, and it was very dependent on the patterns and mechanical properties, characterized via digital opto-electronic holography, laser Doppler vibrometry, and dynamic mechanical analysis. In a different study, the team 3D printed cellular materials with vascular networks for flow [37]. The 3D printed structure was fabricated using an ink composed of Pluronic F-127, GelMA (gelatin methacrylate to allow for UV curing) and fibroblast cell culture. After curing, the Pluronic F-127 was removed by cooling to 4°C, yielding open channels that represent the vascular networks. Lewis’ team demonstrated that blood and other cellular liquids can flow through the channels with minimal death of cells.
\nPatients with skin burns and thick wound injuries often suffer from long term recovery and extensive and expensive treatments. The autologous split-thickness skin graft (ASSG) is the technique most often used to treat large wounds [38]. A skin tissue is place in the injured area and assists with the wound closure and healing. This technique relies on the removal of a piece of skin from a different part of the patient’s body and reapplying it on the place of injury. The drawback with ASSG is that it is limited by the size of donor sites and also creates another place of injury [38]. 3D printing of biomaterials would alleviate the problems related to ASSG. Skin cells are cultured in a laboratory and mixed with biocompatible polymers for bioprinting. In 2012, Koch Singh et al. [39] reported the 3D printing of skin using a laser-based inkjet printing method. The inks were composed of blood plasma/alginate solution and fibroblast/keratinocytes/collagen biomaterials. Collagen is the main component of the extracellular matrix (ECM) in skin. The team proved that the laser-based printing method does not harm the cells by performing proliferation of the cells in histologic sections 10 days after printing. Ki-67 staining, which includes the protein present in cells during their active cell cycle phases, shows that proliferating cells can be found in all regions, verifying vitality. In addition, a build-up of basal lamina, cell adhesion and proliferation- sign of tissue generation was observed.
\nThe dental industry is taking advantage of 3D printing technologies for restoratives, implants, and orthodontics purposes. Currently, professionals in the dental field have access to 3D printers and it is possible to print designs in a clinical environment. A CT scan is used to generate a defined shape based on the patient’s morphology and quickly fabricate and replace a missing tooth [40]. 3D printing is used for the manufacturing of aligners, braces, dental implants, and crowns [40]. Biocompatible materials are used for the fabrication of dental parts using 3D printing, e.g. polylactic acid, polycaprolactone and polyglycolide, and acrylates [3]. It is possible to fabricate dental implants with antibacterial properties by the incorporation of additives, such as quaternary ammonium salts [41, 42, 43]. At the age of 23, Amos Dudley fabricated his own orthodontic aligners while he was a student at New Jersey Institute of Technology [44]. He used equipment available at the institute to scan and print models of his teeth. A non-toxic plastic was used to mold and eventually generate 12 clear aligners. Amos had access to a Stratasys Dimension 1200 3D printer and used a mixture of alginate powder and PermaStone as the resin to print the aligners, which were tested by fitting them on his teeth. While it was not a trivial problem to solve, Amos proved the ability of 3D printing orthodontic materials for teeth alignment.
\nAM has been widely used in the biomedical industry and will continue to impact work in the future. Some challenges will persist, such as regulatory issues, limited materials, and inconsistent quality [45]. AM biomedical products require FDA approval, which can be time consuming and difficult to obtain [46]. Biocompatibility will require the development of new techniques and materials to produce high quality, high performing AM materials [47]. Furthermore, mechanical properties of AM materials need to be well assessed such that final properties can have reliable and reproducible behaviors. Further development for on-demand and patient-specific applications will be exciting work in this field. For example, designing patient-specific implants following a CT-scan will result in quick results [48]. Complex parts with specific mechanical properties and biocompatibility can be constructed on demand and with multifunctional components if needed. AM Research and development may help to improve bio-printed scaffolds and tissues for clinical applications to reduce cost for tissue engineering [49]. Manufacturing AM artificial organs, which includes multifunctionality (i.e. bionic ear [50]), will revolutionize the field of 3D printing for biomedical applications.
\nOne of the most promising fields in the future of AM is the aerospace industry. According to Wohlers’ report, this industry account for almost 20% of the total AM market today [32]. Aerospace applications typically require light weight and high strength materials. The importance of AM relies on the reduced cost, increased flexibility of design, and increase in a variety of products to meet customer needs. Additive manufacturing is an important technology that enables the design and manufacturing of complex structured products with improved mechanical strength and lower weight, at a lower cost and reduced lead-time. The aerospace industry has replaced the conventional manufacturing methods of molding and machining with 3D printing technology for small scale production. At a small production scale, AM offers effectively low-cost design and assembly [17].
\nThe aerospace industry implemented the use of AM approximately 20 years ago [51]. The main use for 3D printing has been focused on prototyping, modeling and producing jigs, fixtures and tools [17]. Furthermore, AM is used to build replacement parts on-demand when required. The ability to build on-demand spare components reduces costs for the production of parts that may never be used due to them becoming obsolete to new technology, which also saves warehouse storage space. For example, BAE Systems is currently 3D printing window breather pipes used in jetliners [52]. These pipes cost 40% less than pipes manufactured using injection molding processes and are manufactured on an as-needed basis.
\nRecently, NASA designed a rover, named Desert RATS, that can support humans in a pressurized cabin in space [53]. The rover is intended to transport humans to Mars. It contains 70 3D printed parts that include flame-retardant vents and housings, camera mounts, large pod doors, front bumpers, complex electronics, and others. The materials used for the 3D printing of the part used in the rover were ABS, PCABS and PC, and were printed using a FDM Stratasys 3D printer. Piper Aircraft manufactures tools using PC that can withstand hydroforming pressures of 3000 to 6000 psi. Aurora Flight Science additively manufactured wings that weigh one third of the fully dense metal components [54]. Some wings have integrated electronics. Lepron generated 200 different designs for use in piloted helicopters [17]. It is foreseen that aerospace companies will replace small components with 3D printed parts, thus reducing the weight of the machines. Some examples are arm rests, seat belts, food trays, and many others [17].
\nCompanies have adopted AM for fast production without making substantial changes to their products [17]. This modification is mostly due to the fast-changing market and low cost of generating such small builds. Several challenges would have to be overcome to facilitate the growth of AM. Some of these challenges include: (1) current speed of AM machines is slow for bulk production; (2) few polymeric material options; and (3) current machines do not allow for the manufacturing of large components [17, 55]. In the future, it is expected that companies will pursue a completely different business model by performing product customization for end-product while maintaining the on-demand part supply. Future work will focus on the development of multifunctional structures with complex geometries, which allows for novel solutions for complicated problems. AM techniques, such as using functionally graded materials, can be used in order to tailor the mechanical and/or thermal response of components [56]. Furthermore, on-demand manufacturing will reduce costs and eliminates potential damage caused by storage [45].
\nElectronic devices require suitable mechanical, geometrical, and optical functionalities to allow for miniaturization, low energy consumption, and smart capabilities [57]. The production of prototypes and end-products has to rapidly change due to the fast-changing technology. The conventional method for manufacturing electronic devices is using subtractive methods that involve masking and etching of sacrificial materials [58]. AM allows for the reduction of material waste, energy consumption and processing time and steps. 3D printing is being used to substitute steps for mounting and assembling electronic devices [59]. The additive process deposits material in a controlled layer-by-layer process allowing the manufacturing of complex geometries and dimensions. In addition, it enables 3D orientation of important components to improve performance. With miniaturization, AM allows for the manufacturing of small parts that would otherwise be difficult to obtain. AM has found application for thin films [60], inductors [61], solar cells [62], and others. The most common 3D printing techniques for electronics are inkjet and direct writing of conductive inks.
\nJennifer Lewis and colleagues fully 3D printed a quantum-dot (QD) light-emitting diode (LED) system, including green and orange-red light emitters embedded in a silicone matrix [63]. The printed device exhibits a performance of 10–100-fold below the best processed QD-LEP but could potentially be optimized with the addition of an electron-transport layer. A copper nanoparticle stabilized with polyvinyl pyrrolidine was mixed with 2-(2-butoxyethoxy)ethanol to prepare ink for inkjet printing [64]. The ink was printed onto a polyimide subtracted and sintered at 200°C. The prepared electronic device resulted in low electrical resistivity (≥ 3.6 μΩcm, or ≥ 2.2 times the resistivity of bulk copper). Bionic ears were printed using an inkjet printer [50]. The inks were composed of cell-cultured alginate and chondrocytes hydrogel matrix and a conductive polymer consisting of silicone and silver nanoparticles. The 3D printed ears exhibit enhanced auditory sensing for radio-frequency reception allowing the ear to listen to stereo music. This result demonstrates that bioengineering and electronics can be merged, resulting in advanced technologies. Students from Northwest Nazaren University and Caldwell High School designed the 3D printed CubeSat [65]. The CubeSat was launched aboard Delta II rocket as part of a NASA mission in 2013. It carries miniaturized electronics and sensors and is intended to collect real-time data on the effects of the harsh environments of space (oxygen, UV, radiation, temperature and collisions) on the polymeric materials- ABS, PLA, Nylon, and PEI/PC ULTEM.
\nFuture research and development in the electronics field will take advantage of low cost methods, flexibility in design, and fast speed of 3D printers for designing and prototyping new products. For example, printing circuit boards will offer superior accuracy and flexibility, with potential cost savings, environmental impacts, faster production times, and increased design versatility. Furthermore, adaptive 3D printing, which takes advantage of a closed-loop method that combines real-time feedback control and DIW of functional materials to construct devices on dynamic surfaces, is an exciting field of research [66]. This method of 3D printing may lead to new forms of smart manufacturing technologies for directly printed wearable devices. New possibilities will emerge in the wearable device industry, in biological and biomedical research, and in the study and treatment of advanced medical treatments.
\nUnsurprisingly, the amount of plastic pollution on the planet is alarming [67]. Plastics have dominated our marketplace due to their utility and versatility and make up at least 10% by mass of our waste streams. Plastics are designed to be durable and to withstand harsh environmental conditions. Therefore, the amount of plastic waste is only expected to increase in the future. Currently, 91% of plastic is not being recycled. The negative impact plastics have on our ecosystem is well recognized and researchers are using this as a business model and opportunity [68, 69]. Considerable efforts are being placed on recycling and reusing plastic waste. Prof. Sahajwalla at the University of New South Wales Sydney and her team work on turning plastic waste into usable polymers, including 3D printing polymers [70]. The company Reflow is collecting polyethylene terephthalate (PET) waste bottles and turning them into filaments suitable for 3D FDM printers [71]. A company in Belgium, Yuma, is using recycled plastics for the 3D printing of sunglasses [72]. The U.S. Army Research Laboratory and the U.S. Marine Corps are working together to repurpose plastic waste by printing items from recycled plastic useful for soldiers [73]. This process allows for a decrease in transportation costs and manufacturing of parts on demand. This large effort is expected to have a positive impact on both the environment and communities by turning polymer 3D printing into income for waste collectors and removing waste from the streams.
\nIndustries are moving toward the implementation of 3D printing as a manufacturing process because it facilitates the design of complex structures and rapid production of prototypes. AM utilizes a computer-aided design software that allows for the design of architectures with defined porosity and structures at a microscopic level. Because of the easy production of 3D printed prototypes, modeling based on a specific application can be performed to further improve the design of the end product and potentially reduce failure risks. The 3D printing of polymers and polymer composites has significantly progressed over the last 40 years and is expected to increase in the near future. Thermoplastic materials are readily commercially available for use in FDM, SLS, and inkjet processes. Materials like PC, ABS, PLA, ULTEM, and PCLA are commonly used for the manufacturing of tools, prototypes, and items used in the aerospace industry. However, these polymers are not one-size-fits-all types of polymers and are not necessary a good choice for all applications. Thus, research efforts are focused on developing materials that are capable of meeting specific applications. For examples, polymers blended with cultured cells can be used for scaffolds and implants on biological systems. Cells can be obtained from the patient and cultivated in the laboratory, thus producing a material that is less likely to be rejected by the patient. Fillers and additives can be used to generate multifunctional materials with improved mechanical properties. Fillers, such as CNTs and graphene, can be incorporated into the polymer to produce a material that is electrically conductive.
\nDespite all of the advances in the design and development of new polymeric materials for AM applications, challenges still remain. The availability of polymeric inks suitable for extreme applications, such as low temperature environments, high load pressures, and radiation resistance, is very limited. The development of new materials is necessary to increase the usefulness of polymer 3D printing technologies. Ideally, some of these composites are recyclable and/or biodegradable to reduce the negative impact plastics have on our environment.
\nWe thank the US Department of Energy’s National Nuclear Security Administration contract DE-AC-52-06NA25396 for providing financial support.
\nThe authors declare no conflict of interest.
The Internet has irrevocably changed the dynamics of scholarly communication and publishing. Consequently, we find it necessary to indicate, unambiguously, our definition of what we consider to be a published scientific work.
",metaTitle:"Prior Publication Policy",metaDescription:"Prior Publication Policy",metaKeywords:null,canonicalURL:"/page/prior-publication-policy",contentRaw:'[{"type":"htmlEditorComponent","content":"A significant number of working papers, early drafts, and similar work in progress are openly shared online between members of the scientific community. It has become common to announce one’s own research on a personal website or a blog to gather comments and suggestions from other researchers. Such works and online postings are, indeed, published in the sense that they are made publicly available. However, this does not mean that if submitted for publication by IntechOpen they are not original works. We differentiate between reviewed and non-reviewed works when determining whether a work is original and has been published in a scholarly sense or not.
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\\n\\nIn order to facilitate the tracking of a manuscript’s publishing history and its development from its earliest draft to the manuscript submitted, we encourage Authors to disclose any instances of a manuscript’s prior publication, whether it be through a conference presentation, a newspaper article, a working paper publicly available in a repository or a blog post.
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\\n\\nAll submitted manuscripts originating from a previously published conference paper must contain at least 50% of new original content to be accepted for review and considered for publication.
\\n\\nAuthors are required to report any links their manuscript might have with their earlier conference papers and presentations in a note to the Academic Editor, as well as in the manuscript itself. Additionally, Authors should obtain any necessary permissions from the publisher of their conference paper if copyright transfer occurred during the publishing process. Failure to do so may prevent Us from publishing an otherwise worthy work.
\\n\\n2. NEWSPAPER & MAGAZINE ARTICLES
\\n\\nNewspaper and magazine articles usually do not pass through any extensive peer or editorial review and we do not consider them to be published in the scholarly sense. Articles appearing in newspapers and magazines rarely possess the depth and structure characteristic of scholarly articles.
\\n\\nSubmitted manuscripts stemming from a previous newspaper or magazine article will be accepted for review and considered for publication. However, Authors are strongly advised to report any such publication in an accompanying note to the External Editor.
\\n\\nAs with the conference papers and presentations, Authors should obtain any necessary permissions from the newspaper or magazine that published the work, and indicate that they have done so in a note to the External Editor.
\\n\\n3. GREY LITERATURE
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\\n\\nAlthough such papers are regularly made publicly available via personal websites and institutional repositories, their general purpose is to gather comments and feedback from Authors’ colleagues in order to further improve a manuscript intended for future publication.
\\n\\nWhen submitting their work, Authors are required to disclose the existence of any publicly available earlier drafts in a note to the Academic Editor. In cases where earlier drafts of the submitted version of the manuscript are publicly available, any overlap between the versions will generally not be considered an instance of self-plagiarism.
\\n\\n4. SOCIAL MEDIA, BLOG & MESSAGE BOARD POSTINGS
\\n\\nWe feel that social media, blogs and message boards are generally used with the same intention as grey literature, to formulate ideas for a manuscript and gather early feedback from like-minded researchers in order to improve a particular piece of work before submitting it for publication. Therefore, we do not consider such internet postings to be publication in the scholarly sense.
\\n\\nNevertheless, Authors are encouraged to disclose the existence of any internet postings in which they outline and describe their research or posted passages of their manuscripts in a note to the Academic Editor. Please note that we will not strictly enforce this request in the same way that we would instructions we consider to be part of our conditions of acceptance for publication. We understand that it may be difficult to keep track of all one’s internet postings in which the researcher´s current work might be mentioned.
\\n\\nIn cases where there is any overlap between the Author´s submitted manuscript and related internet postings, we will generally not consider it to be an instance of self-plagiarism. This also holds true for any co-Author as well.
\\n\\nFor more information on this policy please contact permissions@intechopen.com.
\\n\\nPolicy last updated: 2017-03-20
\\n"}]'},components:[{type:"htmlEditorComponent",content:'A significant number of working papers, early drafts, and similar work in progress are openly shared online between members of the scientific community. It has become common to announce one’s own research on a personal website or a blog to gather comments and suggestions from other researchers. Such works and online postings are, indeed, published in the sense that they are made publicly available. However, this does not mean that if submitted for publication by IntechOpen they are not original works. We differentiate between reviewed and non-reviewed works when determining whether a work is original and has been published in a scholarly sense or not.
\n\nThe significance of Peer Review cannot be overstated when it comes to defining, in our terms, what constitutes a published scientific work. Peer Review is widely considered to be the cornerstone of modern publishing processes and the key value-adding contribution to a scholarly manuscript that a publisher can make.
\n\nOther than the issue of originality, research misconduct is another major issue that all publishers have to address. IntechOpen’s Retraction & Correction Policy and various publication ethics guidelines identify both redundant publication and (self)plagiarism to fall within the definition of research misconduct, thus constituting grounds for rejection or the issue of a Retraction if the work has already been published.
\n\nIn order to facilitate the tracking of a manuscript’s publishing history and its development from its earliest draft to the manuscript submitted, we encourage Authors to disclose any instances of a manuscript’s prior publication, whether it be through a conference presentation, a newspaper article, a working paper publicly available in a repository or a blog post.
\n\nA note to the Academic Editor containing detailed information about a submitted manuscript’s previous public availability is the preferred means of reporting prior publication. This helps us determine if there are any earlier versions of a manuscript that should be disclosed to our readers or if any of those earlier versions should be cited and listed in a manuscript’s references.
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\n\nAll submitted manuscripts originating from a previously published conference paper must contain at least 50% of new original content to be accepted for review and considered for publication.
\n\nAuthors are required to report any links their manuscript might have with their earlier conference papers and presentations in a note to the Academic Editor, as well as in the manuscript itself. Additionally, Authors should obtain any necessary permissions from the publisher of their conference paper if copyright transfer occurred during the publishing process. Failure to do so may prevent Us from publishing an otherwise worthy work.
\n\n2. NEWSPAPER & MAGAZINE ARTICLES
\n\nNewspaper and magazine articles usually do not pass through any extensive peer or editorial review and we do not consider them to be published in the scholarly sense. Articles appearing in newspapers and magazines rarely possess the depth and structure characteristic of scholarly articles.
\n\nSubmitted manuscripts stemming from a previous newspaper or magazine article will be accepted for review and considered for publication. However, Authors are strongly advised to report any such publication in an accompanying note to the External Editor.
\n\nAs with the conference papers and presentations, Authors should obtain any necessary permissions from the newspaper or magazine that published the work, and indicate that they have done so in a note to the External Editor.
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\n\nWhite papers, working papers, technical reports and all other forms of papers which fall within the scope of the ‘Luxembourg definition’ of grey literature do not pass through any extensive peer or editorial review and we do not consider them to be published in the scholarly sense.
\n\nAlthough such papers are regularly made publicly available via personal websites and institutional repositories, their general purpose is to gather comments and feedback from Authors’ colleagues in order to further improve a manuscript intended for future publication.
\n\nWhen submitting their work, Authors are required to disclose the existence of any publicly available earlier drafts in a note to the Academic Editor. In cases where earlier drafts of the submitted version of the manuscript are publicly available, any overlap between the versions will generally not be considered an instance of self-plagiarism.
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\n\nWe feel that social media, blogs and message boards are generally used with the same intention as grey literature, to formulate ideas for a manuscript and gather early feedback from like-minded researchers in order to improve a particular piece of work before submitting it for publication. Therefore, we do not consider such internet postings to be publication in the scholarly sense.
\n\nNevertheless, Authors are encouraged to disclose the existence of any internet postings in which they outline and describe their research or posted passages of their manuscripts in a note to the Academic Editor. Please note that we will not strictly enforce this request in the same way that we would instructions we consider to be part of our conditions of acceptance for publication. We understand that it may be difficult to keep track of all one’s internet postings in which the researcher´s current work might be mentioned.
\n\nIn cases where there is any overlap between the Author´s submitted manuscript and related internet postings, we will generally not consider it to be an instance of self-plagiarism. This also holds true for any co-Author as well.
\n\nFor more information on this policy please contact permissions@intechopen.com.
\n\nPolicy last updated: 2017-03-20
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Shohel"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},subject:{topic:{id:"463",title:"International Trade",slug:"international-trade",parent:{id:"72",title:"International Economics",slug:"international-economics"},numberOfBooks:3,numberOfSeries:0,numberOfAuthorsAndEditors:44,numberOfWosCitations:38,numberOfCrossrefCitations:49,numberOfDimensionsCitations:76,videoUrl:null,fallbackUrl:null,description:null},booksByTopicFilter:{topicId:"463",sort:"-publishedDate",limit:12,offset:0},booksByTopicCollection:[{type:"book",id:"6487",title:"Trade and Global Market",subtitle:null,isOpenForSubmission:!1,hash:"7f1afebc7552003672f0c62b354538be",slug:"trade-and-global-market",bookSignature:"Vito Bobek",coverURL:"https://cdn.intechopen.com/books/images_new/6487.jpg",editedByType:"Edited by",editors:[{id:"128342",title:"Prof.",name:"Vito",middleName:null,surname:"Bobek",slug:"vito-bobek",fullName:"Vito Bobek"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"5492",title:"International Trade",subtitle:"On the Brink of Change",isOpenForSubmission:!1,hash:"f64d7edf6aef7b32784cc01a18836699",slug:"international-trade-on-the-brink-of-change",bookSignature:"Anita Macek",coverURL:"https://cdn.intechopen.com/books/images_new/5492.jpg",editedByType:"Edited by",editors:[{id:"142587",title:"Dr.",name:"Anita",middleName:null,surname:"Maček",slug:"anita-macek",fullName:"Anita Maček"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"2355",title:"International Trade from Economic and Policy Perspective",subtitle:null,isOpenForSubmission:!1,hash:"8fe6804794ddc1a7f4202db20aed5985",slug:"international-trade-from-economic-and-policy-perspective",bookSignature:"Vito Bobek",coverURL:"https://cdn.intechopen.com/books/images_new/2355.jpg",editedByType:"Edited by",editors:[{id:"128342",title:"Prof.",name:"Vito",middleName:null,surname:"Bobek",slug:"vito-bobek",fullName:"Vito Bobek"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],booksByTopicTotal:3,seriesByTopicCollection:[],seriesByTopicTotal:0,mostCitedChapters:[{id:"38487",doi:"10.5772/48103",title:"A Perspective on Remanufacturing Business: Issues and Opportunities",slug:"a-perspective-on-remanufacturing-business-issues-and-opportunities",totalDownloads:4193,totalCrossrefCites:10,totalDimensionsCites:20,abstract:null,book:{id:"2355",slug:"international-trade-from-economic-and-policy-perspective",title:"International Trade from Economic and Policy Perspective",fullTitle:"International Trade from Economic and Policy Perspective"},signatures:"Mosè Gallo, Elpidio Romano and Liberatina Carmela Santillo",authors:[{id:"11826",title:"Prof.",name:"Elpidio",middleName:null,surname:"Romano",slug:"elpidio-romano",fullName:"Elpidio Romano"},{id:"11827",title:"Prof.",name:"Liberatina",middleName:null,surname:"Santillo",slug:"liberatina-santillo",fullName:"Liberatina Santillo"},{id:"138996",title:"PhD.",name:"Mosè",middleName:null,surname:"Gallo",slug:"mose-gallo",fullName:"Mosè Gallo"}]},{id:"58969",doi:"10.5772/intechopen.72953",title:"Corruption, Causes and Consequences",slug:"corruption-causes-and-consequences",totalDownloads:27364,totalCrossrefCites:11,totalDimensionsCites:13,abstract:"Corruption is a constant in the society and occurs in all civilizations; however, it has only been in the past 20 years that this phenomenon has begun being seriously explored. It has many different shapes as well as many various effects, both on the economy and the society at large. Among the most common causes of corruption are the political and economic environment, professional ethics and morality and, of course, habits, customs, tradition and demography. Its effects on the economy (and also on the wider society) are well researched, yet still not completely. Corruption thus inhibits economic growth and affects business operations, employment and investments. It also reduces tax revenue and the effectiveness of various financial assistance programs. The wider society is influenced by a high degree of corruption in terms of lowering of trust in the law and the rule of law, education and consequently the quality of life (access to infrastructure, health care). There also does not exist an unambiguous answer as to how to deal with corruption. Something that works in one country or in one region will not necessarily be successful in another. This chapter tries to answer at least a few questions about corruption and the causes for it, its consequences and how to deal with it successfully.",book:{id:"6487",slug:"trade-and-global-market",title:"Trade and Global Market",fullTitle:"Trade and Global Market"},signatures:"Štefan Šumah",authors:[{id:"228073",title:"Mr.",name:"Stefan",middleName:null,surname:"Sumah",slug:"stefan-sumah",fullName:"Stefan Sumah"}]},{id:"61175",doi:"10.5772/intechopen.75812",title:"Trade Openness and Economic Growth: Empirical Evidence from Transition Economies",slug:"trade-openness-and-economic-growth-empirical-evidence-from-transition-economies",totalDownloads:3417,totalCrossrefCites:7,totalDimensionsCites:11,abstract:"The relationship between trade openness and economic growth is ambiguous from both theoretical and empirical point of view. The theoretical propositions reveal that while trade openness leads to a greater economic efficiency, market imperfections, differences in technology and endowments may lead to adverse effect of trade liberalisation on individual countries. In this chapter, we re-examine the empirical evidence pointing to the benefits of trade liberalisation and bring theoretical issues on possible adverse effect of openness to the fore. It has been argued that ‘passive’ trade liberalisation may not necessarily lead to positive economic outcomes, particularly in less advanced transition economies. Considering the empirical work on the matter, a lot of controversies are related to measurement issues. We find that openness measured by trade intensity indicators may lead to misleading conclusions about the trade growth nexus. Hence, the discussion of policy implications regarding the positive influence of trade barriers on economic growth goes well beyond the context of transition.",book:{id:"6487",slug:"trade-and-global-market",title:"Trade and Global Market",fullTitle:"Trade and Global Market"},signatures:"Sabina Silajdzic and Eldin Mehic",authors:[{id:"233162",title:"Associate Prof.",name:"Sabina",middleName:null,surname:"Silajdzic",slug:"sabina-silajdzic",fullName:"Sabina Silajdzic"},{id:"233367",title:"Prof.",name:"Eldin",middleName:null,surname:"Mehic",slug:"eldin-mehic",fullName:"Eldin Mehic"}]},{id:"38485",doi:"10.5772/48151",title:"Transboundary Animal Diseases and International Trade",slug:"transboundary-animal-diseases-and-international-trade",totalDownloads:3950,totalCrossrefCites:2,totalDimensionsCites:6,abstract:null,book:{id:"2355",slug:"international-trade-from-economic-and-policy-perspective",title:"International Trade from Economic and Policy Perspective",fullTitle:"International Trade from Economic and Policy Perspective"},signatures:"Andrés Cartín-Rojas",authors:[{id:"139628",title:"Ms.",name:"Andrés",middleName:null,surname:"Cartín-Rojas",slug:"andres-cartin-rojas",fullName:"Andrés Cartín-Rojas"}]},{id:"53521",doi:"10.5772/66628",title:"Tourism Invisible Part of Exports: The Analysis of Slovenia and Montenegro on the Chinese Outbound Tourism",slug:"tourism-invisible-part-of-exports-the-analysis-of-slovenia-and-montenegro-on-the-chinese-outbound-to",totalDownloads:1499,totalCrossrefCites:3,totalDimensionsCites:4,abstract:"People’s Republic of China is the largest, Slovenia is the 64th and Montenegro is the 162nd largest export economy in the world. Methods of analysis, deduction and induction and comparative method were used in this paper. The paper reviews and analyzes statistical data of international trade with China as well as of Chinese outbound tourism and provides an estimate of what share Slovenia and Montenegro received. Starting off with the research question ‘Are the revenue from the export of China and revenue from Chinese inbound tourism (‘invisible export’) in gross domestic product (GDP) growing?’ we have concluded that China is becoming a more important partner for both countries. There is a strong positive correlation between exports in China and the number of overnights of Chinese tourists both in Slovenia and Montenegro and that expenditure of Chinese tourists visiting these two countries increases every year as well. Expenditure and share of expenditure of Chinese tourists visiting Slovenia and Montenegro in Chinese exports increase every year. Share of expenditure of Chinese tourists and export in Chinese GDP increase every year.",book:{id:"5492",slug:"international-trade-on-the-brink-of-change",title:"International Trade",fullTitle:"International Trade - On the Brink of Change"},signatures:"Andrej Raspor, Ana Stranjančević, Iva Bulatović and Darko\nLacmanović",authors:[{id:"193991",title:"Dr.",name:"Andrej",middleName:null,surname:"Raspor",slug:"andrej-raspor",fullName:"Andrej Raspor"},{id:"194137",title:"Dr.",name:"Ana",middleName:null,surname:"Stranjančević",slug:"ana-stranjancevic",fullName:"Ana Stranjančević"},{id:"194138",title:"Dr.",name:"Iva",middleName:null,surname:"Bulatović",slug:"iva-bulatovic",fullName:"Iva Bulatović"},{id:"194139",title:"Dr.",name:"Darko",middleName:null,surname:"Lacmanović",slug:"darko-lacmanovic",fullName:"Darko Lacmanović"}]}],mostDownloadedChaptersLast30Days:[{id:"58969",title:"Corruption, Causes and Consequences",slug:"corruption-causes-and-consequences",totalDownloads:27405,totalCrossrefCites:11,totalDimensionsCites:13,abstract:"Corruption is a constant in the society and occurs in all civilizations; however, it has only been in the past 20 years that this phenomenon has begun being seriously explored. It has many different shapes as well as many various effects, both on the economy and the society at large. Among the most common causes of corruption are the political and economic environment, professional ethics and morality and, of course, habits, customs, tradition and demography. Its effects on the economy (and also on the wider society) are well researched, yet still not completely. Corruption thus inhibits economic growth and affects business operations, employment and investments. It also reduces tax revenue and the effectiveness of various financial assistance programs. The wider society is influenced by a high degree of corruption in terms of lowering of trust in the law and the rule of law, education and consequently the quality of life (access to infrastructure, health care). There also does not exist an unambiguous answer as to how to deal with corruption. Something that works in one country or in one region will not necessarily be successful in another. This chapter tries to answer at least a few questions about corruption and the causes for it, its consequences and how to deal with it successfully.",book:{id:"6487",slug:"trade-and-global-market",title:"Trade and Global Market",fullTitle:"Trade and Global Market"},signatures:"Štefan Šumah",authors:[{id:"228073",title:"Mr.",name:"Stefan",middleName:null,surname:"Sumah",slug:"stefan-sumah",fullName:"Stefan Sumah"}]},{id:"61175",title:"Trade Openness and Economic Growth: Empirical Evidence from Transition Economies",slug:"trade-openness-and-economic-growth-empirical-evidence-from-transition-economies",totalDownloads:3424,totalCrossrefCites:7,totalDimensionsCites:11,abstract:"The relationship between trade openness and economic growth is ambiguous from both theoretical and empirical point of view. The theoretical propositions reveal that while trade openness leads to a greater economic efficiency, market imperfections, differences in technology and endowments may lead to adverse effect of trade liberalisation on individual countries. In this chapter, we re-examine the empirical evidence pointing to the benefits of trade liberalisation and bring theoretical issues on possible adverse effect of openness to the fore. It has been argued that ‘passive’ trade liberalisation may not necessarily lead to positive economic outcomes, particularly in less advanced transition economies. Considering the empirical work on the matter, a lot of controversies are related to measurement issues. We find that openness measured by trade intensity indicators may lead to misleading conclusions about the trade growth nexus. Hence, the discussion of policy implications regarding the positive influence of trade barriers on economic growth goes well beyond the context of transition.",book:{id:"6487",slug:"trade-and-global-market",title:"Trade and Global Market",fullTitle:"Trade and Global Market"},signatures:"Sabina Silajdzic and Eldin Mehic",authors:[{id:"233162",title:"Associate Prof.",name:"Sabina",middleName:null,surname:"Silajdzic",slug:"sabina-silajdzic",fullName:"Sabina Silajdzic"},{id:"233367",title:"Prof.",name:"Eldin",middleName:null,surname:"Mehic",slug:"eldin-mehic",fullName:"Eldin Mehic"}]},{id:"59359",title:"Analysis of the Role of Exchange Rate Volatility in Monetary Policy Conduction in OECD Countries: Empirical Evidence from Panel-VAR Models",slug:"analysis-of-the-role-of-exchange-rate-volatility-in-monetary-policy-conduction-in-oecd-countries-emp",totalDownloads:1503,totalCrossrefCites:0,totalDimensionsCites:2,abstract:"In this study, panel vector autoregression (PVAR) models are employed to examine the relationships between industrial production growth rate, consumer price inflation, short-term interest rates, stock returns and exchange rate volatility. More specifically, I explored the consequences of the dynamics detected by the models on monetary policy implementation for 10 OECD countries. This study indicates that factors that may cause a rise in short-term interest rates with respect to the USA can lead to volatility in exchange rates and thus macroeconomic instability. It is also implied that sustaining macroeconomic growth and decreasing inflation can result in increased export performance, which in turn provides the amount of US dollars to curb volatility in US dollar quotations. Accordingly, this study reveals that high importance should be given to both monetary and non-monetary factors in the open-economy framework to detect the possible impacts on trade and capital flows by dynamic stochastic general equilibrium (DSGE) models. Due to their exchange rate risk of economic agents, I also suggest that the economic policy makers of these countries had better create a theoretical framework including financial frictions, economic agents’ preferences and different shocks to smooth the variations in exchange rates and minimise the negative outcomes of Brexit.",book:{id:"6487",slug:"trade-and-global-market",title:"Trade and Global Market",fullTitle:"Trade and Global Market"},signatures:"Oguzhan Ozcelebi",authors:[{id:"226325",title:"Prof.",name:"Oguzhan",middleName:null,surname:"Ozcelebi",slug:"oguzhan-ozcelebi",fullName:"Oguzhan Ozcelebi"}]},{id:"53827",title:"Malaysia and China: The Trade Balances, Foreign Exchanges and Crises Impacts",slug:"malaysia-and-china-the-trade-balances-foreign-exchanges-and-crises-impacts",totalDownloads:2046,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"China appears as the biggest trading partner for ASEAN economies, but it is inconclusive whether the complementarities between China and regional economies offset China’s competitive threat. This study tries to assess if real exchange fluctuations and the demand-supply channels determine the Malaysia-China trade balances in the global crises era, 1997–2010. The finding generally supports the complementary role of China in the Malaysia-China bilateral trading. However, despite the long-run effect of real exchange on trade balances, the Keynesian demand channel was not uphold during and after the global financial crisis—due to the contractionary effect on Malaysian output. The Chinese inflation impact is also not evident following the foreign exchange shocks. Meanwhile, currency devaluation for exports gains is insufficient to sustain Malaysia output expansion against China. Further productivity growth in real and tradable sectors is essentially needed.",book:{id:"5492",slug:"international-trade-on-the-brink-of-change",title:"International Trade",fullTitle:"International Trade - On the Brink of Change"},signatures:"Tze-Haw Chan",authors:[{id:"191390",title:"Dr.",name:"Chan",middleName:null,surname:"Tze-Haw",slug:"chan-tze-haw",fullName:"Chan Tze-Haw"}]},{id:"53059",title:"Brazil in the Twenty-First-Century International Trade: Challenges and Opportunities",slug:"brazil-in-the-twenty-first-century-international-trade-challenges-and-opportunities",totalDownloads:1731,totalCrossrefCites:3,totalDimensionsCites:3,abstract:"This chapter discusses the impacts of globalization on international trade patterns and the required shifts in trade policies. 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