Result of measurement of 50 ng/L Cr(III) in the presence of 50 ng/L interfering metal ions.
\\n\\n
Released this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\\n\\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
\\n"}]',published:!0,mainMedia:{caption:"Highly Cited",originalUrl:"/media/original/117"}},components:[{type:"htmlEditorComponent",content:'IntechOpen is proud to announce that 191 of our authors have made the Clarivate™ Highly Cited Researchers List for 2020, ranking them among the top 1% most-cited.
\n\nThroughout the years, the list has named a total of 261 IntechOpen authors as Highly Cited. Of those researchers, 69 have been featured on the list multiple times.
\n\n\n\nReleased this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\n\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
\n'}],latestNews:[{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"},{slug:"introducing-intechopen-book-series-a-new-publishing-format-for-oa-books-20210915",title:"Introducing IntechOpen Book Series - A New Publishing Format for OA Books"}]},book:{item:{type:"book",id:"8470",leadTitle:null,fullTitle:"Poultry - An Advanced Learning",title:"Poultry",subtitle:"An Advanced Learning",reviewType:"peer-reviewed",abstract:"Poultry is a one of the biggest meat-producing industries in the world. The success story of the poultry industry largely depends upon continuous research and knowledge sharing. This book is an effort to disseminate the latest information on poultry research among poultry producers, young researchers, students, and farm managers. In this concise text, all key information related to poultry production is included. After reading this book, you will learn the architectural requirements of a poultry house particularly for the tropical environment. You will also understand the advanced genomic and nutritional applications as well as statistical tools needed to optimize poultry production and meat quality. The book will also strengthen knowledge of bird physiology with more emphasis on the reproductive tract of layers.",isbn:"978-1-78923-820-4",printIsbn:"978-1-78923-819-8",pdfIsbn:"978-1-78984-983-7",doi:"10.5772/intechopen.78844",price:100,priceEur:109,priceUsd:129,slug:"poultry-an-advanced-learning",numberOfPages:94,isOpenForSubmission:!1,isInWos:null,isInBkci:!1,hash:"88f09746e2b424573c8dc0bd927e9dbb",bookSignature:"Asghar Ali Kamboh",publishedDate:"April 29th 2020",coverURL:"https://cdn.intechopen.com/books/images_new/8470.jpg",numberOfDownloads:6730,numberOfWosCitations:2,numberOfCrossrefCitations:13,numberOfCrossrefCitationsByBook:0,numberOfDimensionsCitations:27,numberOfDimensionsCitationsByBook:0,hasAltmetrics:0,numberOfTotalCitations:42,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"September 3rd 2018",dateEndSecondStepPublish:"September 24th 2018",dateEndThirdStepPublish:"November 23rd 2018",dateEndFourthStepPublish:"February 11th 2019",dateEndFifthStepPublish:"April 12th 2019",currentStepOfPublishingProcess:5,indexedIn:"1,2,3,4,5,6",editedByType:"Edited by",kuFlag:!1,featuredMarkup:null,editors:[{id:"225390",title:"Dr.",name:"Asghar Ali",middleName:null,surname:"Kamboh",slug:"asghar-ali-kamboh",fullName:"Asghar Ali Kamboh",profilePictureURL:"https://mts.intechopen.com/storage/users/225390/images/system/225390.jpeg",biography:"Dr. Asghar Ali Kamboh was born in Mehrabpur, Sindh, Pakistan. He completed his studies in Veterinary Medicine and Masters in Veterinary Microbiology in 2003 and 2007 respectively, with distinguished grades. In 2009, he was awarded an overseas scholarship by the Government of Pakistan and proceeded to China for doctoral studies. Currently, he is working as an Associate Professor in the Department of Veterinary Microbiology, Sindh Agriculture University, Tandojam. He has edited two books and published more than 100 research and review articles in national and international peer-reviewed journals. He has supervised/co-supervised more than 35 M.Phil students. He is also the author of many books and book chapters. In addition, he is an editor/editorial board member of many scholarly journals in the area of animal health and production.",institutionString:"Sindh Agriculture University",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"0",totalChapterViews:"0",totalEditedBooks:"1",institution:{name:"Sindh Agriculture University",institutionURL:null,country:{name:"Pakistan"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"319",title:"Poultry Science",slug:"poultry-science"}],chapters:[{id:"65864",title:"Poultry Housing and Management",doi:"10.5772/intechopen.83811",slug:"poultry-housing-and-management",totalDownloads:3147,totalCrossrefCites:5,totalDimensionsCites:11,hasAltmetrics:0,abstract:"Majority of the people in the poorest regions of the tropics rely on poultry production as their major source of protein supply. However, poultry production is hindered by the harsh environmental conditions in this regions therefore, reducing the daily supply of protein. It is believed that understanding heat stress in birds by paying detail attention to the sources of heat generation in a poultry house can help manage the heat stress situation in this region. This text reviews the internal climatic conditions of the poultry houses, how the birds respond to them, and their implications for heat management in poultry production. Thus, it provides pertinent information for guidance on parameters for open poultry houses architectural design that ensures optimum climatic conditions that will alleviate heat stress problem in poultry production in hot and humid climate.",signatures:"Ayodeji Oloyo and Adedamola Ojerinde",downloadPdfUrl:"/chapter/pdf-download/65864",previewPdfUrl:"/chapter/pdf-preview/65864",authors:[{id:"273409",title:"Mr.",name:"Ayodeji",surname:"Oloyo",slug:"ayodeji-oloyo",fullName:"Ayodeji Oloyo"},{id:"274920",title:"MSc.",name:"Adedamola",surname:"Ojerinde",slug:"adedamola-ojerinde",fullName:"Adedamola Ojerinde"}],corrections:null},{id:"65551",title:"Investigation of the Effects of Some Herbal Extracts Used in Different Ratios on Meat Fatty Acid Profile Level in Experimental Heat Stress Created in Broilers",doi:"10.5772/intechopen.83751",slug:"investigation-of-the-effects-of-some-herbal-extracts-used-in-different-ratios-on-meat-fatty-acid-pro",totalDownloads:753,totalCrossrefCites:0,totalDimensionsCites:1,hasAltmetrics:0,abstract:"Stress is the biological or external alteration of the organism against the factors that make it possible to achieve hemostasis or normal physiological balance. In our world, temperature increase due to climate change has become one of the most important stress factors in poultry sector. This research investigated the effects of essential oil mixture (EOM; Eucalyptus globulus Labill, Thymus vulgaris, Cymbopogon nardus, and Syzygium aromaticum) broilers adding to the drinking water under heat stress conditions. The fatty acid profile was evaluated. In a 42-day study, 400 Ross-308 male chickens (1-day-old) were randomly assigned to eight different groups (n = 50), each containing five subgroups (n = 10). As a result of the research, in stress-free groups 22°C rations of myristic acid (C14:0), palmitic acid (C16:0), stearic acid (C18:0), oleic acid (C18:1), linoleic acid (C18:2n-6t), and Cis 11 eicosapentaenoic acid (C 20: 1n9) increased, whereas MUFA, UFA, and behenic acid (C22:0) reduced. However, in stressed groups, 36°C rations of myristic acid (C14:0), palmitic acid (C16:0), stearic acid (C18:0), and arachidonic acid (C20:0) decreased, increased the UFA ratio, and had no effect on the MUFA and PUFA.",signatures:"Emre Tekce, Bülent Bayraktar and Vecihi Aksakal",downloadPdfUrl:"/chapter/pdf-download/65551",previewPdfUrl:"/chapter/pdf-preview/65551",authors:[{id:"273192",title:"Ph.D.",name:"Emre",surname:"Tekce",slug:"emre-tekce",fullName:"Emre Tekce"},{id:"278225",title:"Dr.",name:"Bülent",surname:"Bayraktar",slug:"bulent-bayraktar",fullName:"Bülent Bayraktar"},{id:"278226",title:"Prof.",name:"Vecihi",surname:"Aksakal",slug:"vecihi-aksakal",fullName:"Vecihi Aksakal"}],corrections:null},{id:"66081",title:"Genetic and Hormonal Regulation of Egg Formation in the Oviduct of Laying Hens",doi:"10.5772/intechopen.85011",slug:"genetic-and-hormonal-regulation-of-egg-formation-in-the-oviduct-of-laying-hens",totalDownloads:1234,totalCrossrefCites:6,totalDimensionsCites:12,hasAltmetrics:0,abstract:"The chicken oviduct is a unique organ in which ovulated yolk transforms into a complete egg. Ovarian hormones induce the cellular and biochemical changes in the oviducts during the egg formation and oviposition. Estradiol regulates the folliculogenesis, accumulation of yolk in the follicles, ovulation, and development of oviducts. Estradiol also induces glandular development and expression of the genes responsible for egg white proteins. Progesterone induces the ovulation of yolk from the ovary, and development of oviductal glands. In addition, several genes are spatiotemporally expressed in the magnum for albumen synthesis and deposition around the yolk, in the isthmus for shell membranes synthesis, and in the uterus for eggshell biomineralization. This chapter highlights the involvement of hormones, genes/proteins, and their interaction for egg formation in the oviduct of laying hens.",signatures:"Birendra Mishra, Nirvay Sah and Sanjeev Wasti",downloadPdfUrl:"/chapter/pdf-download/66081",previewPdfUrl:"/chapter/pdf-preview/66081",authors:[{id:"274927",title:"Dr.",name:"Birendra",surname:"Mishra",slug:"birendra-mishra",fullName:"Birendra Mishra"},{id:"290539",title:"Dr.",name:"Nirvay",surname:"Sah",slug:"nirvay-sah",fullName:"Nirvay Sah"},{id:"290540",title:"Dr.",name:"Sanjeev",surname:"Wasti",slug:"sanjeev-wasti",fullName:"Sanjeev Wasti"}],corrections:null},{id:"65400",title:"Regulatory Mechanism and Application of lncRNAs in Poultry",doi:"10.5772/intechopen.83800",slug:"regulatory-mechanism-and-application-of-lncrnas-in-poultry",totalDownloads:1030,totalCrossrefCites:2,totalDimensionsCites:3,hasAltmetrics:0,abstract:"Long noncoding RNA (lncRNAs) are transcripts greater than 200 nt in length with decreased coding potential and are widespread in all types of biological organisms. lncRNAs can interact with protein, DNA and RNA, respectively, which may participate in the multilevel regulation of transcriptional, post-transcriptional and epigenetic modifications. It is well known that lncRNA, which length is single-stranded non-coding RNA molecule, plays crucial roles in animal growth, development, cell proliferation and differentiation, and other life activities. In this research, we review the regulation mechanism and current research status of lncRNAs in chicken economic traits and disease, which would contribute to further understanding the regulatory mechanisms and application of lncRNAs in poultry.",signatures:"Zhuanjian Li, Tuanhui Ren, Wenya Li and Ruili Han",downloadPdfUrl:"/chapter/pdf-download/65400",previewPdfUrl:"/chapter/pdf-preview/65400",authors:[{id:"237484",title:"Dr.",name:"Ruili",surname:"Han",slug:"ruili-han",fullName:"Ruili Han"},{id:"245284",title:"Dr.",name:"Zhuanjian",surname:"Li",slug:"zhuanjian-li",fullName:"Zhuanjian Li"},{id:"279995",title:"Dr.",name:"Tuanhui",surname:"Ren",slug:"tuanhui-ren",fullName:"Tuanhui Ren"},{id:"279996",title:"Dr.",name:"Wenya",surname:"Li",slug:"wenya-li",fullName:"Wenya Li"}],corrections:null},{id:"70650",title:"Some Statistical Analysis of Poultry Feeds Data",doi:"10.5772/intechopen.86361",slug:"some-statistical-analysis-of-poultry-feeds-data",totalDownloads:572,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"In this study we presented generalized exponential power distribution as an alternative to normal distribution commonly used in the analysis of agricultural data. The distribution which is more robust in modeling because of the present of shape parameters, which regulates it tails. Some of its mathematical and statistical properties are examined. The application of the probability density function is demonstrated in fitting poultry feeds data. The goodness-of-fit test was carried to show that it is a better substitute to normal distribution in applications.",signatures:"Akinlolu Adeseye Olosunde",downloadPdfUrl:"/chapter/pdf-download/70650",previewPdfUrl:"/chapter/pdf-preview/70650",authors:[{id:"272739",title:"Ph.D.",name:"Akinlolu Adeseye",surname:"Olosunde",slug:"akinlolu-adeseye-olosunde",fullName:"Akinlolu Adeseye Olosunde"}],corrections:null}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},subseries:null,tags:null},relatedBooks:[{type:"book",id:"5315",title:"Poultry Science",subtitle:null,isOpenForSubmission:!1,hash:"d2b2b8ff84b12d9afe428b7d059b0b46",slug:"poultry-science",bookSignature:"Milad Manafi",coverURL:"https://cdn.intechopen.com/books/images_new/5315.jpg",editedByType:"Edited by",editors:[{id:"56772",title:"Dr.",name:"Milad",surname:"Manafi",slug:"milad-manafi",fullName:"Milad Manafi"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6623",title:"Application of Genetics and Genomics in Poultry Science",subtitle:null,isOpenForSubmission:!1,hash:"ee6c1f2e58822c19bc014a9684cad0da",slug:"application-of-genetics-and-genomics-in-poultry-science",bookSignature:"Xiaojun Liu",coverURL:"https://cdn.intechopen.com/books/images_new/6623.jpg",editedByType:"Edited by",editors:[{id:"183723",title:"Dr.",name:"Xiaojun",surname:"Liu",slug:"xiaojun-liu",fullName:"Xiaojun Liu"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10361",title:"Advances in Poultry Nutrition Research",subtitle:null,isOpenForSubmission:!1,hash:"a68c18aa7790ca6fb772998ac9357d8d",slug:"advances-in-poultry-nutrition-research",bookSignature:"Amlan Kumar Patra",coverURL:"https://cdn.intechopen.com/books/images_new/10361.jpg",editedByType:"Edited by",editors:[{id:"310962",title:"Dr.",name:"Amlan",surname:"Patra",slug:"amlan-patra",fullName:"Amlan Patra"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1591",title:"Infrared Spectroscopy",subtitle:"Materials Science, Engineering and Technology",isOpenForSubmission:!1,hash:"99b4b7b71a8caeb693ed762b40b017f4",slug:"infrared-spectroscopy-materials-science-engineering-and-technology",bookSignature:"Theophile Theophanides",coverURL:"https://cdn.intechopen.com/books/images_new/1591.jpg",editedByType:"Edited by",editors:[{id:"37194",title:"Dr.",name:"Theophile",surname:"Theophanides",slug:"theophile-theophanides",fullName:"Theophile Theophanides"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3161",title:"Frontiers in Guided Wave Optics and Optoelectronics",subtitle:null,isOpenForSubmission:!1,hash:"deb44e9c99f82bbce1083abea743146c",slug:"frontiers-in-guided-wave-optics-and-optoelectronics",bookSignature:"Bishnu Pal",coverURL:"https://cdn.intechopen.com/books/images_new/3161.jpg",editedByType:"Edited by",editors:[{id:"4782",title:"Prof.",name:"Bishnu",surname:"Pal",slug:"bishnu-pal",fullName:"Bishnu Pal"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3092",title:"Anopheles mosquitoes",subtitle:"New insights into malaria vectors",isOpenForSubmission:!1,hash:"c9e622485316d5e296288bf24d2b0d64",slug:"anopheles-mosquitoes-new-insights-into-malaria-vectors",bookSignature:"Sylvie Manguin",coverURL:"https://cdn.intechopen.com/books/images_new/3092.jpg",editedByType:"Edited by",editors:[{id:"50017",title:"Prof.",name:"Sylvie",surname:"Manguin",slug:"sylvie-manguin",fullName:"Sylvie Manguin"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"371",title:"Abiotic Stress in Plants",subtitle:"Mechanisms and Adaptations",isOpenForSubmission:!1,hash:"588466f487e307619849d72389178a74",slug:"abiotic-stress-in-plants-mechanisms-and-adaptations",bookSignature:"Arun Shanker and B. 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\r\n\tanimal life inside an environment. These fields include Nuclear Physics, Industrial Processes, Environmental
\r\n\tSciences, Radiation Biology, Radiation Chemistry, Radiotherapy, Agriculture and Forestry, and Food industry.
\r\n\tUranium mining is the process of extraction of uranium ore from the ground. Many different types of uranium
\r\n\tdeposits have been discovered and mined. There are mainly three types of uranium. The book covers an
\r\n\toverview of Gamma Background Radiations and Measurements, Radioactive Decay, Radioecological, Applications
\r\n\tIn Environmental Gamma Dosimetry, Gamma and Alpha Interaction, Influence of Gamma Radiation on Dynamical
\r\n\tMechanical Properties, Influence of Low Dose Gamma Irradiation Treatments on The Microbial Decontamination,
\r\n\tGamma Ray Ionization Enhancement in Tissues, Modeling Plastic Deformation Location in Irradiated Materials,
\r\n\tRadiotherapy, Radon gas, isotopes, Alpha emission rates Application of Radiation and Genetic Engineering
\r\n\tTechniques, Gamma Ray Measurements Using different devices. This book is expected to benefit undergraduate
\r\n\tand postgraduate students, researchers, teachers, practitioners, policymakers, and every individual who has a
\r\n\tconcern for a healthy life.
Searching strategies for finding targets using appropriate sensing modalities are of great importance in many aspects of life. In the context of national security, there could be a need to find a source of hazardous emissions [1, 2, 3]. Similarly, rescue and recovery missions may be tasked with localising a lost piece of equipment that is emitting weak signals [4]. Biological applications include, for example, protein searching for its specific target site on DNA [5], or foraging behaviour of animals in their search for food or a mate [6, 7]. The objective of search research [8] is to develop optimal strategies for localising a target in the shortest time (on average), for a given search volume and sensing characteristics.
The use of autonomous vehicles in dangerous missions, such as finding a source of hazardous emissions, has become widespread [9, 10, 11]. Existing approaches to the search and localisation in the context of atmospheric releases can be loosely divided into three categories: up-flow motion methods, concentration gradient-based methods and information gain-based methods, also known as
This chapter summarizes our recent results in development of an autonomous infotaxic coordinated search strategy for a group of robots, searching for an emitting hazardous source in open terrain under turbulent conditions. The assumption is that the search platforms can move and sense. Two types of sensor measurements are collected sequentially: (a) the concentration of the hazardous substance; (b) the platform location within the search domain. Due to the turbulent transport of the emitted substance, the concentration measurements are typically sporadic and fluctuating. The searching platforms form a moving sensor network, thus enabling the exchange of data and a cooperative behaviour. The multi-robot infotaxis have already been studied in [16, 17, 20, 24]. However, all mentioned references assumed
We develop an approach where the group of searching robots operate in a fully decentralised coordinated manner. Decentralised operation means that each searching robot performs the computations (i.e., source estimation and path planning) locally and independently of other platforms. Having a common task, however the robotic platforms must perform in a coordinated manner. This coordination is achieved by exchanging the data with immediate neighbours only, in a manner which does not require the global knowledge of the communication network topology. For this reason, the proposed approach is scalable in the sense that the complexities for sensing, communication, and computing per sensor platform are independent of the sensor network size. In addition, because all sensor platforms are treated equally (no leader-follower hierarchy), this approach is robust to the failure of any of the searching agents. The only requirement for avoiding the break-up of the searching formation is that the communication graph of the sensor network remains
First, we describe the measurement model. The concentration measurements are modelled using a Lagrange encounters model developed in [13], based on an open field assumption and a two-dimensional geometry. Let
where
The probability that a sensor at location
Parameter
The motion model of a coordinated group of robots is described next. Let the pose vector of the
For each platform
The measurements of concentration are taken at time instants
Motion of the
where vector
Here,
An example of a formation of
A robotic platform can communicate with another platform of the formation, if their mutual distance is smaller than a certain range
Estimation and robot motion control are carried out using the measurement dissemination-based decentralised fusion architecture [25]. Measurement locations2 and the corresponding measured concentration values, i.e., the triple
Suppose the posterior density function of the source at discrete-time
where
where
is independent of
where the posterior of source strength
Since the conjugate prior of the Poisson distribution is the Gamma distribution [28], the posterior
The parameters of the prior for source strength,
Next, we turn our attention to the posterior of source position
where
The Rao-Blackwellised particle filter (RBPF) fully describes the posterior
Here,
In decentralised multi-robot search, each platform autonomously makes a decision at time
A robot platform
where
Previous studies of search strategies [3, 20] found that the reward function defined as the
where
while
where
Given that
In order to compute
where the product
Thus, (17) is approximated with
Pseudo-code of the routine for the computation of control vector on platform
Algorithm 1 Computation of
1:
2: Compute
3: Create admissible set
4:
5: Compute the future platform location
6: Compute
7: Determine
8: Compute
9: Calculate the expected reward
10:
11: Find
12:
So far, we have explained how platform
We apply decentralised cooperative control based on the average consensus [30, 31]. In a network of collaborating agents, consensus is an iterative protocol designed to reach an agreement regarding a certain quantity of interest. Suppose that every platform, as a node in the communication network, initially has an individual scalar value. The goal of average consensus is for every node in the network to compute the average of initial scalar values, in a completely decentralised manner: by communicating only with the neighbours in the communication graph (without knowing the topology of the communication graph).
In the problem we consider, there is not only a single individual scalar value, but six of them. They include three motion control parameters, i.e., for platform
Let us denote the scalar value of interest by
Ideally, we want every platform in the formation to compute the mean value
Average consensus is an iterative algorithm. At iteration
where
The search continues until the global stopping criterion is satisfied. The local stopping criterion is calculated on each platform independently based on the spread of the local positional particles
The global stopping criterion is computed on each platform using the average consensus algorithm, using (21), but with
We point out that both estimation and control are based on the consensus algorithm. While the cooperative control is using the
The proposed search algorithm has been applied to an experimental dataset, collected by COANDA Research & Development Corporation using their large recirculating water channel. The emitting source was releasing fluorescent dye at a constant rate from a narrow tube. The dataset comprises a sequence of 340 frames of instantaneous concentration field measurements in the vertical plane and is sampled at every 10/23 s. The size of a frame is
An example of the search algorithm running on the experimental data is shown in Figure 2. All physical quantities are in arbitrary units (a.u.). The following environmental/sensing parameters were used:
Experimental dataset: an illustrative run of the decentralised multi-robot search using
Figure 2 displays the top-down view of the search progress at step indices
Using 200 Monte Carlo simulations, the mean search time for the algorithm was 2525 a.u., with a 5th and 95th quantile of 1840 and 3445 a.u., respectively. Note that in all simulations the formation started from the bottom right hand corner indicated in Figure 2(a).
The chapter presented a decentralised infotaxic search algorithm for a group of autonomous robotic platforms. The algorithm allows the platforms to search and locate a source of hazardous emissions in a coordinated manner without the need for a centralised fusion and control system. More precisely, this distributed coordination is achieved only by local exchange of measurement data between neighbouring platforms. Similarly, the movement decisions taken by the platforms were reached using a distributed average consensus algorithm over the whole formation. The key aspect is that individual platforms only require knowledge of their neighbours; the global knowledge of the communication network topology is unnecessary. An advantage of adopted distributed framework is that all platforms are treated equally, making the proposed search algorithm scalable and robust to the failure of a single platform. Numerical results using experimental data confirmed the robust performance of the algorithm. The main limitation of the algorithm is that the environmental parameters (such as diffusivity, the average direction and speed of the wind, particle lifetime), must be known. Future work will explore sensitivity to parametrisation and will aim to develop a team of “search and rescue” robots for further experimentation in realistic environments.
This research was supported in part by the Defence Science and Technology Group through its Strategic Research Initiative on Trusted Autonomous Systems.
Chromium occurs in nature in two valencies, Cr(III) and Cr(VI). The two ionic species have distinct toxicity and reactivity [1]. Cr(VI) has high toxicity, while Cr(III) is less toxic, and the latter is also known to be one of the essential ions for humans, which is required in particular amount in the diet [2]. Due to their opposite nature in toxicity, it is important to distinguish between Cr(III) and Cr(VI). Therefore, specific and sensitive determination methods to distinguish both of the species are required.
\nSince Cr(III) belongs to essential nutrition ion required for maintaining normal physiological function, thus trace amount determination of Cr(VI) becomes very important to avoid toxic intake in the diets [3]. There have been several sensitive methods used for Cr(III) and Cr(VI) determination including atomic absorption spectrophotometry (AAS) [4, 5], plasma mass spectroscopy [6], spectrofluorimetry [7], chemiluminescence [8], spectrophotometry [9], and electrochemical methods [10, 11, 12]. Determination of chromium ions using voltammetric method is evolving along with the requirements to accurately measure the ionic species [13, 14, 15, 16, 17, 18].
\nThe material of working electrode influences the performance of voltammetric method. Application of carbon-based electrode utilization is currently growing in electroanalytical field because it has some advantages including wide electrical potential range, low background current, inexpensive, inert, and suitable for a wide variety of sensors [19]. Modification of the electrode is being explored to enhance the electrode performance [20, 21]. The modified electrode needs to be evaluated for their performance. In the present chapter, investigation of carbon-based electrode without and with modification was evaluated for their performance to determine Cr(VI) and Cr(III).
\nFor determination of Cr(III) using graphite pencil electrode (GPE), three solvents were trialed [21], i.e., 0.01 M hydrochloric acid, acetate buffer pH 5.0, and double distilled water. Potential range from -800 to 1000 mV with 90 s deposition time, 10 s cleaning time, and 20 mV/s scan rate was used for the measurement using anodic stripping voltammetry. This experiment was performed to measure the background signal in order to get a correction factor which can avoid the presence of undesired peak current from the solvent. No peak was detected when 0.01 M hydrochloric acid was used at the condition applied, while acetate buffer pH 5.0 and double distilled water gave relatively high peak current which can interfere the measurement (data not shown). Therefore, hydrochloric acid was chosen as solvent for the method. For further experiment, Cr(III) solution was made by dissolving Cr(III) chloride in 0.01 M hydrochloric acid as solvent.
\nAn experiment for investigating the linearity of the method was performed by measuring Cr(III) within 1–500 ppm range. The experiment was performed using a potential range of −1.5 to +1.0 V with 60 s of deposition time, 10 s of cleaning time, and 50 mV/s of scan rate. The electrode used in the experiment was pencil graphite electrode, and the linear concentration range was determined by correlating height of peak current and concentration of Cr(III). The linear concentration range was found in 12.5–75 ppm range, and the result is presented in Figure 1.
\nTypical peak response of chromium(III) voltammogram using PGE. Experiment condition: solvent = 0.01 M hydrochloric acid, chromium(III) concentration = 12.5, 25, 50, 62.5, and 75 ppm was performed sequentially with 60 s of deposition time, 50 mV/s of scan rate, and deposition potential at −1260 mV [
The range of linear concentration at 12.5–75 ppm gave correlation coefficient of 0.9936, which indicate good relationship with correlation equation of y = 0.1778x + 0.747. PGE can be used as working electrode for determination of Cr(III) with optimum condition achieved at 60 s of deposition time and 50 mV/s of scan rate. Linear range of Cr(III) measurement with the proposed condition was 12.5–75 ppm with 0.31 ppm limit of detection.
\nThe addition of a chelating agent in the form of ligands to the Cr(VI) signal measurements has been done in several previous studies such as addition of rubeanic acid ligand [22] and addition of diethylenetriaminepentaacetic acid (DTPA) as ligand with electrolyte support of morpholinoethanesulfonate acid buffer (MES) [23]. From previous studies it can be concluded that the addition of a ligand for the measurement of Cr(VI) signal by voltammetry can increase the measurement sensitivity [24]. Figure 2 shows that after the addition of the DTPA, the peak generated on the voltammogram becomes specific, and no further undesirable impurity peaks occur (black line designated as d). After background correction, it can be concluded that with the addition of DTPA, the impurity peaks were reduced, a specific peak on the voltammogram was produced, and the peak current height of chromium increases so that the measurement sensitivity also increases.
\nVoltammogram of (a) 0.2 M acetate buffer pH 6.0, (b) DTPA 868 ppm, (c) 30 ppm Cr(VI), and (d) 30 ppm Cr(VI) with addition of DTPA. Measurement conditions: potential deposition, +810 mV; deposition time, 60 s; scan speed, 50 mV/s; potential range, +2000 V to −2000 mV.
Calibration curve was prepared by measuring differential pulse adsorptive stripping voltammetry of Cr(VI) with the following concentrations: 1, 10, 20, and 30 ppm. The voltammetric measurement was carried out at a potential deposition condition of +810 mV, a scan rate of 50 mV/s, and a deposition time of 60 s with stirring using a magnetic stirrer.
\nFrom Figure 3 it can be seen that the peak current height increases with increasing analyte concentration in the voltammetric cell. This may be due to the increasing number of Cr species deposited on the working electrode when the analytical concentration is added, thereby increasing the peak current in the voltammogram. The linear regression of the standard curve is y = 0.6319x + 8.5796 with correlation coefficient of 0.957.
\nVoltammogram of Cr(VI) using PGE with concentration of (a) 1, (b) 10, (c) 20, and (d) 30 ppm with DTPA addition. Measurement conditions: potential deposition, +810 mV; deposition time, 60 s; scan rate, 50 mV/s; potential range, +2000 V to −2000 mV.
The measurement of Cr(VI) peak current was performed triplicate to calculate precision value. For 1 ppm, a fairly low standard deviation was obtained which is 0.3466. This indicates that the measurement results have a fairly good accuracy or precision, and from the calculation, the coefficient of variation of 4.56% was also obtained. The addition of DTPA as ligand can be used to detect Cr(VI) and can produce a specific peak for Cr(VI) at a potential region of −0.6474 V.
\nAuNP was synthesized using citric ion as capping agent. After reduction using NaBH4 solution, the gold solution color was changed from yellow to red ruby (λmax = 518 nm), which indicate that AuNP colloid was formed with average dimension of 2–5 nm [25]. Characterization using TEM indicates that the average diameter of the colloid was ~2.2 nm (Figure 4). This gold nanoparticle was then used to modify the GCE.
\nTEM image of gold nanoparticles.
GCE was modified by attaching AuNP onto the electrode surface. Modification of GCE was initiated by polishing the electrode followed by activation. This step was performed so that the electrode can be covered evenly and maximally by the AuNP, which eventually can increase sensitivity when used to determine the analyte. Photochemical reaction is one of the many methods to activate the GCE surface. The photochemical reaction was performed by immersing the electrode into concentrated ammonium hydroxide and followed by irradiation under UV light for 6 hours at 254 nm [26]. This process is known as self-assembly which can substitute hydrogen group (–H) with amine group (–NH2) of the electrode. Due to the nature of the amine group, more AuNP can be attached to the electrode and improve binding to the electrode [27], as indicated by SEM-EDS data. SEM-EDS data demonstrated that the self-assembly process was better than the adsorption process. Modification of GCE by self-assembly process reached 11.55% of AuNP covering the electrode (Figure 5), while the adsorption process (direct immersion of the electrode) only reached 2.05% covering according to SEM-EDS data.
\nSEM image of gold nanoparticle-modified glassy carbon electrode surface. Modification was conducted using (a) adsorption and (b) self-assembly process.
From the present study, it was found that optimum deposition potential and deposition time for determination of 0.5 μg/L Cr(VI) in 0.01 M hydrochloric acid as supporting electrolyte solution were 800 mV and 120 s, respectively. The optimum condition was then applied to develop a calibration curve with concentration ranging from 0 to 25 μg/L, and the current density to potential data of the concentrations is presented in Figure 6. From the data, a linear calibration curve (r2 = 0.9896) was developed and is presented on Figure 7 with correlation coefficient and linear regression equation of 0.9911 and I = 2.25 × 10−3 C + 5.89 × 10−4, respectively. Through calculation, it was obtained that limit of detection and precision of the method are 2.38 ng/L and 99.14%, respectively.
\nVoltammogram of various chromium(VI) concentrations (0–0.25 μg/L) with AuNP-GCE. The condition of measurement is as follows: deposition potential, deposition time, scan rate, and amplitude modulation at 800 mV, 120 s, 50 mV/s, and 500 mV, respectively.
Calibration curve of various chromium(VI) concentrations with deposition potential, deposition time, scan rate, and amplitude modulation at 800 mV, 120 s, 50 mV/s, and 500 mV, respectively.
To see whether we can distinguish Cr(VI) from Cr(III) using condition described earlier, we measure individual and mixture of the ionic species. The result is presented in Figure 8. In contrast with Cr(VI), it was found that in this condition Cr(III) does not give a sharp peak. However, it seems that the peak of the mixture was slightly reduced compared to Cr(VI) peak. Therefore, we can measure Cr(VI) in this condition with a neglected effect from Cr(III).
\nVoltammogram of Cr(III) and Cr(VI) and mixture of Cr(III) and Cr(VI) in 0.01 M hydrochloric acid using AuNP-GCE against Ag/AgCl with deposition potential of 800 mV, deposition time of 120 s, and amplitude modulation of 0.05 V.
To determine the optimum condition for determination of Cr(III) using AuNP-GCE, a preliminary experiment was conducted by varying deposition potential. The potential used were ranging from −2.0 to −1.0 V with scan rate and amplitude modulation of 0.05 V/s and 0.05 V, respectively. The highest efficiency for Cr(III) 500 ppb in 0.2 M acetate buffer was found at −1.5 V, while optimization of deposition time leads us to conclude that the best result was obtained at 90 s [17]. The optimized parameters are very crucial in stripping step that have pronounced effect on both sensitivity and linear range. Therefore, from the preliminary experiment, we conclude that the optimum condition for determination of Cr(III) using AuNP-GCE is using −1.5 V of deposition potential and 90 s of deposition time.
\nThe optimum condition was then applied to prepare a calibration curve of Cr(III) using AuNP-GCE differential pulse stripping voltammetry. The calibration curve was obtained by varying concentration of Cr(III) and measuring it at −1.5 V of deposition potential, 90 s of deposition time, 0.05 V/s of scan rate, and 0.05 V of amplitude modulation. The voltammetric measurement and calibration curve are presented in Figure 9. By calculation, a linear regression equation and correlation coefficient of y = 0.142 + 0.004x and r = 0.9955, respectively, were obtained. The result showed that the linear range was obtained at 0.5–75 ppb range. The reproducibility of the method was then determined from the replicate measurement of 1 ppb Cr(III). The calculation results in a mean of current response of 0.14 μA ppb−1, which is referred to as sensitivity of the method. It corresponds to the value of relative standard deviation (RSD) of 2.4%. Based on calculation suggested by Miller and Miller [28], limit of detection of the method is 0.01 ppb, which is three times of the value of standard deviation baseline. Utilization of AuNP-modified electrode improves at least one order of magnitude detection limit compared to voltammetric method using film electrode. Limited publication of voltammetric detection of Cr(III) compared to Cr(VI) and poor sensitivity of non-gold electrode lead us to infer that gold or gold-modified electrodes are required to get high-quality Cr(III) voltammetric profiles. It is previously reported that high-quality voltammetric profiles for Cr(III) appear when gold electrode is used [29].
\nVoltammetric performance for Cr(III) concentration variation. Inset shows corresponding calibration curve at an optimum condition.
Optimum condition was then applied for determination of Cr(III) in electroplating wastewater, which is a more complex matrix than the standard solution. Based on standard addition method, we found that the concentration of Cr(III) in the sample was 0.146 ppm, corresponding to 97% recovery and in good agreement with the result from AAS method (AAnalyst 400, PerkinElmer) after appropriate extraction. Therefore, the proposed voltammetric method using the fabricated electrochemical AuNP-GCE sensor gives satisfactory result and is applicable for determination of Cr(III) in complex matrix, such as wastewater.
\nThere is a possibility that Cr(VI) interferes the Cr(III) measurement in the proposed condition. Therefore, we measure the voltammogram of individual and mixture of the ionic species. The results are presented in Figure 10. From the figure, it is clear that by using the proposed condition, clear peak was only detected for Cr(III) species, while Cr(VI) did not show any significant peak at the corresponding potential. Mixture of Cr(III) and Cr(VI) also gives similar peak which corresponds to the individual Cr(VI) peak.
\nVoltammogram Cr(III) and Cr(VI) and mixture of Cr(III) and Cr(VI) in acetate buffer pH 5 using AuNP-GCE electrode against Ag/AgCl electrode with deposition potential of −1500 mV, deposition time of 90 s, and amplitude modulation of 50 mV.
In order to evaluate the effect of foreign metal ions dissolved in the media, solutions containing 50 ppb of Cr(III) and each of the following metals Cd(II), Cu(II), Zn(II), Cr(VI), Ni(II), and Fe(III) all at the same concentration of 50 ppb were prepared. Measurement was conducted at an optimum condition described in Subchapter 4, and the result is presented in Table 1. The effect of interfering metal ion on Cr(III) was indicated by the change in peak current signal during measurement. The addition of foreign ions does not influence the peak current corresponding to Cr(III). The percentage variations of the peak current induced by the presence of interfering ions with respect to Cr(III) alone are 1.02% for Cd(II), 0.88% for Cu(II), 0.29% for Zn(II), 3.70% for Cr(VI), 0.07% for Ni(II), and 0.40% for Fe(III). These deviations from Cr(III) measurement at 0.9470 V and 1.360 μA remain acceptable, and, therefore, the accurate detection of Cr(III) is still possible under these conditions.
\nInterfering metal ion | \nPotential (V) | \nCurrent (μA) | \nChange (%) | \n
---|---|---|---|
None | \n0.9470 | \n1.360 | \n– | \n
Cd(II) | \n0.8857 | \n1.374 | \n1.02 | \n
Cu(II) | \n0.8357 | \n1.348 | \n0.88 | \n
Zn(II) | \n0.8507 | \n1.356 | \n0.29 | \n
Cr(VI) | \n0.9359 | \n1.323 | \n3.7 | \n
Ni(II) | \n0.9100 | \n1.361 | \n0.07 | \n
Fe(III) | \n0.8507 | \n1.356 | \n0.4 | \n
Result of measurement of 50 ng/L Cr(III) in the presence of 50 ng/L interfering metal ions.
Cd(II) and Zn(II) ions have a standard reduction potential similar to Cr(III) ion. During the current measurement of Cr(III) with the presence of interfering ions, they also deposited on the electrode surface, reducing the amount of Cr(III) on the electrode surface. At the deposition stage, when −1.5 V electric potential was applied, the ions will be reduced too because their standard reduction potential are more positive than the deposition potential applied. The effect of interfering metal ion is presented in Figure 11.
\nDifferential pulse voltammogram of Cr(III) using AuNP-GCE with −1.5 V of deposition potential, 90 s of deposition time, 0.05 V/s of scan rate, and 0.05 V of amplitude modulation against Ag/AgCl. Concentration of Cr(III) was 50 ppb in acetate buffer pH 5 without and with the presence of Cd(II), Cu(II), Zn(II), Cr(VI), Ni(II), or Fe(III) as interfering ions with concentration of 50 ppb.
Fe(III), Cr(VI), Cu(II), and Ni(II) ions have more positive standard reduction potential than Cr(III), and therefore when −1.5 V potential was applied, the interfering ions were also reduced and causing less Cr(III) reduced than it should be. Therefore, the peak of Cr(III) is reduced, while Zn(II) and Cd(II) have more negative standard reduction potential than Cr(III), and therefore when reduction potential was applied, Cr(III) will be reduced followed, in order, by Zn(II) and Cd(II).
\nCarbon-based electrode can be applied as working electrode for the determination of Cr(III) and Cr(VI). PGE can detect the presence of Cr(III) in solution, while for Cr(VI) addition of DTPA is needed to get a specific peak current of Cr(VI). The two methods utilizing PGE can detect Cr(III) and Cr(VI) in ppm scale. To enhance the analytical performance, AuNP-GCE was used as working electrode, and it showed better results. The modified electrode can measure both Cr(III) and Cr(VI) in ppb scale. By using a different condition, we succeeded to measure Cr(III) and Cr(VI) with the same working electrode.
\nThe authors would like to acknowledge the financial support from the Academic Leadership Grant Program, Universitas Padjadjaran, and the Directorate of Research and Community Service through Superior Research of Higher Education (DRPM-PDUPT).
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Saxena",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",institutionString:"King George's Medical University",institution:{name:"King George's Medical University",institutionURL:null,country:{name:"India"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},subseriesFiltersForPublishedBooks:[{group:"subseries",caption:"Bacterial Infectious Diseases",value:3,count:2},{group:"subseries",caption:"Parasitic Infectious Diseases",value:5,count:4},{group:"subseries",caption:"Viral Infectious Diseases",value:6,count:7}],publicationYearFilters:[{group:"publicationYear",caption:"2022",value:2022,count:2},{group:"publicationYear",caption:"2021",value:2021,count:4},{group:"publicationYear",caption:"2020",value:2020,count:3},{group:"publicationYear",caption:"2019",value:2019,count:3},{group:"publicationYear",caption:"2018",value:2018,count:1}],authors:{paginationCount:249,paginationItems:[{id:"274452",title:"Dr.",name:"Yousif",middleName:"Mohamed",surname:"Abdallah",slug:"yousif-abdallah",fullName:"Yousif Abdallah",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/274452/images/8324_n.jpg",biography:"I certainly enjoyed my experience in Radiotherapy and Nuclear Medicine, particularly it has been in different institutions and hospitals with different Medical Cultures and allocated resources. Radiotherapy and Nuclear Medicine Technology has always been my aspiration and my life. As years passed I accumulated a tremendous amount of skills and knowledge in Radiotherapy and Nuclear Medicine, Conventional Radiology, Radiation Protection, Bioinformatics Technology, PACS, Image processing, clinically and lecturing that will enable me to provide a valuable service to the community as a Researcher and Consultant in this field. My method of translating this into day to day in clinical practice is non-exhaustible and my habit of exchanging knowledge and expertise with others in those fields is the code and secret of success.",institutionString:null,institution:{name:"Majmaah University",country:{name:"Saudi Arabia"}}},{id:"313277",title:"Dr.",name:"Bartłomiej",middleName:null,surname:"Płaczek",slug:"bartlomiej-placzek",fullName:"Bartłomiej Płaczek",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/313277/images/system/313277.jpg",biography:"Bartłomiej Płaczek, MSc (2002), Ph.D. (2005), Habilitation (2016), is a professor at the University of Silesia, Institute of Computer Science, Poland, and an expert from the National Centre for Research and Development. His research interests include sensor networks, smart sensors, intelligent systems, and image processing with applications in healthcare and medicine. He is the author or co-author of more than seventy papers in peer-reviewed journals and conferences as well as the co-author of several books. He serves as a reviewer for many scientific journals, international conferences, and research foundations. Since 2010, Dr. Placzek has been a reviewer of grants and projects (including EU projects) in the field of information technologies.",institutionString:"University of Silesia",institution:{name:"University of Silesia",country:{name:"Poland"}}},{id:"35000",title:"Prof.",name:"Ulrich H.P",middleName:"H.P.",surname:"Fischer",slug:"ulrich-h.p-fischer",fullName:"Ulrich H.P Fischer",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/35000/images/3052_n.jpg",biography:"Academic and Professional Background\nUlrich H. P. has Diploma and PhD degrees in Physics from the Free University Berlin, Germany. He has been working on research positions in the Heinrich-Hertz-Institute in Germany. Several international research projects has been performed with European partners from France, Netherlands, Norway and the UK. He is currently Professor of Communications Systems at the Harz University of Applied Sciences, Germany.\n\nPublications and Publishing\nHe has edited one book, a special interest book about ‘Optoelectronic Packaging’ (VDE, Berlin, Germany), and has published over 100 papers and is owner of several international patents for WDM over POF key elements.\n\nKey Research and Consulting Interests\nUlrich’s research activity has always been related to Spectroscopy and Optical Communications Technology. Specific current interests include the validation of complex instruments, and the application of VR technology to the development and testing of measurement systems. He has been reviewer for several publications of the Optical Society of America\\'s including Photonics Technology Letters and Applied Optics.\n\nPersonal Interests\nThese include motor cycling in a very relaxed manner and performing martial arts.",institutionString:null,institution:{name:"Charité",country:{name:"Germany"}}},{id:"341622",title:"Ph.D.",name:"Eduardo",middleName:null,surname:"Rojas Alvarez",slug:"eduardo-rojas-alvarez",fullName:"Eduardo Rojas Alvarez",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/341622/images/15892_n.jpg",biography:null,institutionString:null,institution:{name:"University of Cuenca",country:{name:"Ecuador"}}},{id:"215610",title:"Prof.",name:"Muhammad",middleName:null,surname:"Sarfraz",slug:"muhammad-sarfraz",fullName:"Muhammad Sarfraz",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/215610/images/system/215610.jpeg",biography:"Muhammad Sarfraz is a professor in the Department of Information Science, Kuwait University, Kuwait. His research interests include optimization, computer graphics, computer vision, image processing, machine learning, pattern recognition, soft computing, data science, and intelligent systems. Prof. Sarfraz has been a keynote/invited speaker at various platforms around the globe. He has advised/supervised more than 110 students for their MSc and Ph.D. theses. He has published more than 400 publications as books, journal articles, and conference papers. He has authored and/or edited around seventy books. Prof. Sarfraz is a member of various professional societies. He is a chair and member of international advisory committees and organizing committees of numerous international conferences. He is also an editor and editor in chief for various international journals.",institutionString:"Kuwait University",institution:{name:"Kuwait University",country:{name:"Kuwait"}}},{id:"32650",title:"Prof.",name:"Lukas",middleName:"Willem",surname:"Snyman",slug:"lukas-snyman",fullName:"Lukas Snyman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/32650/images/4136_n.jpg",biography:"Lukas Willem Snyman received his basic education at primary and high schools in South Africa, Eastern Cape. He enrolled at today's Nelson Metropolitan University and graduated from this university with a BSc in Physics and Mathematics, B.Sc Honors in Physics, MSc in Semiconductor Physics, and a Ph.D. in Semiconductor Physics in 1987. After his studies, he chose an academic career and devoted his energy to the teaching of physics to first, second, and third-year students. After positions as a lecturer at the University of Port Elizabeth, he accepted a position as Associate Professor at the University of Pretoria, South Africa.\r\n\r\nIn 1992, he motivates the concept of 'television and computer-based education” as means to reach large student numbers with only the best of teaching expertise and publishes an article on the concept in the SA Journal of Higher Education of 1993 (and later in 2003). The University of Pretoria subsequently approved a series of test projects on the concept with outreach to Mamelodi and Eerste Rust in 1993. In 1994, the University established a 'Unit for Telematic Education ' as a support section for multiple faculties at the University of Pretoria. In subsequent years, the concept of 'telematic education” subsequently becomes well established in academic circles in South Africa, grew in popularity, and is adopted by many universities and colleges throughout South Africa as a medium of enhancing education and training, as a method to reaching out to far out communities, and as a means to enhance study from the home environment.\r\n\r\nProfessor Snyman in subsequent years pursued research in semiconductor physics, semiconductor devices, microelectronics, and optoelectronics.\r\n\r\nIn 2000 he joined the TUT as a full professor. Here served for a period as head of the Department of Electronic Engineering. Here he makes contributions to solar energy development, microwave and optoelectronic device development, silicon photonics, as well as contributions to new mobile telecommunication systems and network planning in SA.\r\n\r\nCurrently, he teaches electronics and telecommunications at the TUT to audiences ranging from first-year students to Ph.D. level.\r\n\r\nFor his research in the field of 'Silicon Photonics” since 1990, he has published (as author and co-author) about thirty internationally reviewed articles in scientific journals, contributed to more than forty international conferences, about 25 South African provisional patents (as inventor and co-inventor), 8 PCT international patent applications until now. Of these, two USA patents applications, two European Patents, two Korean patents, and ten SA patents have been granted. A further 4 USA patents, 5 European patents, 3 Korean patents, 3 Chinese patents, and 3 Japanese patents are currently under consideration.\r\n\r\nRecently he has also published an extensive scholarly chapter in an internet open access book on 'Integrating Microphotonic Systems and MOEMS into standard Silicon CMOS Integrated circuitry”.\r\n\r\nFurthermore, Professor Snyman recently steered a new initiative at the TUT by introducing a 'Laboratory for Innovative Electronic Systems ' at the Department of Electrical Engineering. The model of this laboratory or center is to primarily combine outputs as achieved by high-level research with lower-level system development and entrepreneurship in a technical university environment. Students are allocated to projects at different levels with PhDs and Master students allocated to the generation of new knowledge and new technologies, while students at the diploma and Baccalaureus level are allocated to electronic systems development with a direct and a near application for application in industry or the commercial and public sectors in South Africa.\r\n\r\nProfessor Snyman received the WIRSAM Award of 1983 and the WIRSAM Award in 1985 in South Africa for best research papers by a young scientist at two international conferences on electron microscopy in South Africa. He subsequently received the SA Microelectronics Award for the best dissertation emanating from studies executed at a South African university in the field of Physics and Microelectronics in South Africa in 1987. In October of 2011, Professor Snyman received the prestigious Institutional Award for 'Innovator of the Year” for 2010 at the Tshwane University of Technology, South Africa. This award was based on the number of patents recognized and granted by local and international institutions as well as for his contributions concerning innovation at the TUT.",institutionString:null,institution:{name:"University of South Africa",country:{name:"South Africa"}}},{id:"317279",title:"Mr.",name:"Ali",middleName:"Usama",surname:"Syed",slug:"ali-syed",fullName:"Ali Syed",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/317279/images/16024_n.png",biography:"A creative, talented, and innovative young professional who is dedicated, well organized, and capable research fellow with two years of experience in graduate-level research, published in engineering journals and book, with related expertise in Bio-robotics, equally passionate about the aesthetics of the mechanical and electronic system, obtained expertise in the use of MS Office, MATLAB, SolidWorks, LabVIEW, Proteus, Fusion 360, having a grasp on python, C++ and assembly language, possess proven ability in acquiring research grants, previous appointments with social and educational societies with experience in administration, current affiliations with IEEE and Web of Science, a confident presenter at conferences and teacher in classrooms, able to explain complex information to audiences of all levels.",institutionString:null,institution:{name:"Air University",country:{name:"Pakistan"}}},{id:"75526",title:"Ph.D.",name:"Zihni Onur",middleName:null,surname:"Uygun",slug:"zihni-onur-uygun",fullName:"Zihni Onur Uygun",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/75526/images/12_n.jpg",biography:"My undergraduate education and my Master of Science educations at Ege University and at Çanakkale Onsekiz Mart University have given me a firm foundation in Biochemistry, Analytical Chemistry, Biosensors, Bioelectronics, Physical Chemistry and Medicine. After obtaining my degree as a MSc in analytical chemistry, I started working as a research assistant in Ege University Medical Faculty in 2014. In parallel, I enrolled to the MSc program at the Department of Medical Biochemistry at Ege University to gain deeper knowledge on medical and biochemical sciences as well as clinical chemistry in 2014. In my PhD I deeply researched on biosensors and bioelectronics and finished in 2020. Now I have eleven SCI-Expanded Index published papers, 6 international book chapters, referee assignments for different SCIE journals, one international patent pending, several international awards, projects and bursaries. In parallel to my research assistant position at Ege University Medical Faculty, Department of Medical Biochemistry, in April 2016, I also founded a Start-Up Company (Denosens Biotechnology LTD) by the support of The Scientific and Technological Research Council of Turkey. Currently, I am also working as a CEO in Denosens Biotechnology. The main purposes of the company, which carries out R&D as a research center, are to develop new generation biosensors and sensors for both point-of-care diagnostics; such as glucose, lactate, cholesterol and cancer biomarker detections. My specific experimental and instrumental skills are Biochemistry, Biosensor, Analytical Chemistry, Electrochemistry, Mobile phone based point-of-care diagnostic device, POCTs and Patient interface designs, HPLC, Tandem Mass Spectrometry, Spectrophotometry, ELISA.",institutionString:null,institution:{name:"Ege University",country:{name:"Turkey"}}},{id:"246502",title:"Dr.",name:"Jaya T.",middleName:"T",surname:"Varkey",slug:"jaya-t.-varkey",fullName:"Jaya T. Varkey",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/246502/images/11160_n.jpg",biography:"Jaya T. Varkey, PhD, graduated with a degree in Chemistry from Cochin University of Science and Technology, Kerala, India. She obtained a PhD in Chemistry from the School of Chemical Sciences, Mahatma Gandhi University, Kerala, India, and completed a post-doctoral fellowship at the University of Minnesota, USA. She is a research guide at Mahatma Gandhi University and Associate Professor in Chemistry, St. Teresa’s College, Kochi, Kerala, India.\nDr. Varkey received a National Young Scientist award from the Indian Science Congress (1995), a UGC Research award (2016–2018), an Indian National Science Academy (INSA) Visiting Scientist award (2018–2019), and a Best Innovative Faculty award from the All India Association for Christian Higher Education (AIACHE) (2019). She Hashas received the Sr. Mary Cecil prize for best research paper three times. She was also awarded a start-up to develop a tea bag water filter. \nDr. Varkey has published two international books and twenty-seven international journal publications. She is an editorial board member for five international journals.",institutionString:"St. Teresa’s College",institution:null},{id:"250668",title:"Dr.",name:"Ali",middleName:null,surname:"Nabipour Chakoli",slug:"ali-nabipour-chakoli",fullName:"Ali Nabipour Chakoli",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/250668/images/system/250668.jpg",biography:"Academic Qualification:\r\n•\tPhD in Materials Physics and Chemistry, From: Sep. 2006, to: Sep. 2010, School of Materials Science and Engineering, Harbin Institute of Technology, Thesis: Structure and Shape Memory Effect of Functionalized MWCNTs/poly (L-lactide-co-ε-caprolactone) Nanocomposites. Supervisor: Prof. Wei Cai,\r\n•\tM.Sc in Applied Physics, From: 1996, to: 1998, Faculty of Physics & Nuclear Science, Amirkabir Uni. of Technology, Tehran, Iran, Thesis: Determination of Boron in Micro alloy Steels with solid state nuclear track detectors by neutron induced auto radiography, Supervisors: Dr. M. Hosseini Ashrafi and Dr. A. Hosseini.\r\n•\tB.Sc. in Applied Physics, From: 1991, to: 1996, Faculty of Physics & Nuclear Science, Amirkabir Uni. of Technology, Tehran, Iran, Thesis: Design of shielding for Am-Be neutron sources for In Vivo neutron activation analysis, Supervisor: Dr. M. Hosseini Ashrafi.\r\n\r\nResearch Experiences:\r\n1.\tNanomaterials, Carbon Nanotubes, Graphene: Synthesis, Functionalization and Characterization,\r\n2.\tMWCNTs/Polymer Composites: Fabrication and Characterization, \r\n3.\tShape Memory Polymers, Biodegradable Polymers, ORC, Collagen,\r\n4.\tMaterials Analysis and Characterizations: TEM, SEM, XPS, FT-IR, Raman, DSC, DMA, TGA, XRD, GPC, Fluoroscopy, \r\n5.\tInteraction of Radiation with Mater, Nuclear Safety and Security, NDT(RT),\r\n6.\tRadiation Detectors, Calibration (SSDL),\r\n7.\tCompleted IAEA e-learning Courses:\r\nNuclear Security (15 Modules),\r\nNuclear Safety:\r\nTSA 2: Regulatory Protection in Occupational Exposure,\r\nTips & Tricks: Radiation Protection in Radiography,\r\nSafety and Quality in Radiotherapy,\r\nCourse on Sealed Radioactive Sources,\r\nCourse on Fundamentals of Environmental Remediation,\r\nCourse on Planning for Environmental Remediation,\r\nKnowledge Management Orientation Course,\r\nFood Irradiation - Technology, Applications and Good Practices,\r\nEmployment:\r\nFrom 2010 to now: Academic staff, Nuclear Science and Technology Research Institute, Kargar Shomali, Tehran, Iran, P.O. Box: 14395-836.\r\nFrom 1997 to 2006: Expert of Materials Analysis and Characterization. Research Center of Agriculture and Medicine. Rajaeeshahr, Karaj, Iran, P. O. Box: 31585-498.",institutionString:"Atomic Energy Organization of Iran",institution:{name:"Atomic Energy Organization of Iran",country:{name:"Iran"}}},{id:"248279",title:"Dr.",name:"Monika",middleName:"Elzbieta",surname:"Machoy",slug:"monika-machoy",fullName:"Monika Machoy",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/248279/images/system/248279.jpeg",biography:"Monika Elżbieta Machoy, MD, graduated with distinction from the Faculty of Medicine and Dentistry at the Pomeranian Medical University in 2009, defended her PhD thesis with summa cum laude in 2016 and is currently employed as a researcher at the Department of Orthodontics of the Pomeranian Medical University. She expanded her professional knowledge during a one-year scholarship program at the Ernst Moritz Arndt University in Greifswald, Germany and during a three-year internship at the Technical University in Dresden, Germany. She has been a speaker at numerous orthodontic conferences, among others, American Association of Orthodontics, European Orthodontic Symposium and numerous conferences of the Polish Orthodontic Society. She conducts research focusing on the effect of orthodontic treatment on dental and periodontal tissues and the causes of pain in orthodontic patients.",institutionString:"Pomeranian Medical University",institution:{name:"Pomeranian Medical University",country:{name:"Poland"}}},{id:"252743",title:"Prof.",name:"Aswini",middleName:"Kumar",surname:"Kar",slug:"aswini-kar",fullName:"Aswini Kar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/252743/images/10381_n.jpg",biography:"uploaded in cv",institutionString:null,institution:{name:"KIIT University",country:{name:"India"}}},{id:"204256",title:"Dr.",name:"Anil",middleName:"Kumar",surname:"Kumar Sahu",slug:"anil-kumar-sahu",fullName:"Anil Kumar Sahu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/204256/images/14201_n.jpg",biography:"I have nearly 11 years of research and teaching experience. I have done my master degree from University Institute of Pharmacy, Pt. Ravi Shankar Shukla University, Raipur, Chhattisgarh India. I have published 16 review and research articles in international and national journals and published 4 chapters in IntechOpen, the world’s leading publisher of Open access books. I have presented many papers at national and international conferences. I have received research award from Indian Drug Manufacturers Association in year 2015. My research interest extends from novel lymphatic drug delivery systems, oral delivery system for herbal bioactive to formulation optimization.",institutionString:null,institution:{name:"Chhattisgarh Swami Vivekanand Technical University",country:{name:"India"}}},{id:"253468",title:"Dr.",name:"Mariusz",middleName:null,surname:"Marzec",slug:"mariusz-marzec",fullName:"Mariusz Marzec",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/253468/images/system/253468.png",biography:"An assistant professor at Department of Biomedical Computer Systems, at Institute of Computer Science, Silesian University in Katowice. Scientific interests: computer analysis and processing of images, biomedical images, databases and programming languages. He is an author and co-author of scientific publications covering analysis and processing of biomedical images and development of database systems.",institutionString:"University of Silesia",institution:null},{id:"212432",title:"Prof.",name:"Hadi",middleName:null,surname:"Mohammadi",slug:"hadi-mohammadi",fullName:"Hadi Mohammadi",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/212432/images/system/212432.jpeg",biography:"Dr. Hadi Mohammadi is a biomedical engineer with hands-on experience in the design and development of many engineering structures and medical devices through various projects that he has been involved in over the past twenty years. Dr. Mohammadi received his BSc. and MSc. degrees in Mechanical Engineering from Sharif University of Technology, Tehran, Iran, and his PhD. degree in Biomedical Engineering (biomaterials) from the University of Western Ontario. He was a postdoctoral trainee for almost four years at University of Calgary and Harvard Medical School. He is an industry innovator having created the technology to produce lifelike synthetic platforms that can be used for the simulation of almost all cardiovascular reconstructive surgeries. He’s been heavily involved in the design and development of cardiovascular devices and technology for the past 10 years. He is currently an Assistant Professor with the University of British Colombia, Canada.",institutionString:"University of British Columbia",institution:{name:"University of British Columbia",country:{name:"Canada"}}},{id:"254463",title:"Prof.",name:"Haisheng",middleName:null,surname:"Yang",slug:"haisheng-yang",fullName:"Haisheng Yang",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/254463/images/system/254463.jpeg",biography:"Haisheng Yang, Ph.D., Professor and Director of the Department of Biomedical Engineering, College of Life Science and Bioengineering, Beijing University of Technology. He received his Ph.D. degree in Mechanics/Biomechanics from Harbin Institute of Technology (jointly with University of California, Berkeley). Afterwards, he worked as a Postdoctoral Research Associate in the Purdue Musculoskeletal Biology and Mechanics Lab at the Department of Basic Medical Sciences, Purdue University, USA. He also conducted research in the Research Centre of Shriners Hospitals for Children-Canada at McGill University, Canada. Dr. Yang has over 10 years research experience in orthopaedic biomechanics and mechanobiology of bone adaptation and regeneration. He earned an award from Beijing Overseas Talents Aggregation program in 2017 and serves as Beijing Distinguished Professor.",institutionString:"Beijing University of Technology",institution:null},{id:"255757",title:"Dr.",name:"Igor",middleName:"Victorovich",surname:"Lakhno",slug:"igor-lakhno",fullName:"Igor Lakhno",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/255757/images/system/255757.jpg",biography:"Lakhno Igor Victorovich was born in 1971 in Kharkiv (Ukraine). \nMD – 1994, Kharkiv National Medical Univesity.\nOb&Gyn; – 1997, master courses in Kharkiv Medical Academy of Postgraduate Education.\nPhD – 1999, Kharkiv National Medical Univesity.\nDSc – 2019, PL Shupik National Academy of Postgraduate Education \nLakhno Igor has been graduated from an international training courses on reproductive medicine and family planning held in Debrecen University (Hungary) in 1997. Since 1998 Lakhno Igor has worked as an associate professor of the department of obstetrics and gynecology of VN Karazin National University and an associate professor of the perinatology, obstetrics and gynecology department of Kharkiv Medical Academy of Postgraduate Education. Since June 2019 he’s a professor of the department of obstetrics and gynecology of VN Karazin National University and a professor of the perinatology, obstetrics and gynecology department of Kharkiv Medical Academy of Postgraduate Education . He’s an author of about 200 printed works and there are 17 of them in Scopus or Web of Science databases. Lakhno Igor is a rewiever of Journal of Obstetrics and Gynaecology (Taylor and Francis), Informatics in Medicine Unlocked (Elsevier), The Journal of Obstetrics and Gynecology Research (Wiley), Endocrine, Metabolic & Immune Disorders-Drug Targets (Bentham Open), The Open Biomedical Engineering Journal (Bentham Open), etc. He’s defended a dissertation for DSc degree \\'Pre-eclampsia: prediction, prevention and treatment”. Lakhno Igor has participated as a speaker in several international conferences and congresses (International Conference on Biological Oscillations April 10th-14th 2016, Lancaster, UK, The 9th conference of the European Study Group on Cardiovascular Oscillations). His main scientific interests: obstetrics, women’s health, fetal medicine, cardiovascular medicine.",institutionString:"V.N. Karazin Kharkiv National University",institution:{name:"Kharkiv Medical Academy of Postgraduate Education",country:{name:"Ukraine"}}},{id:"89721",title:"Dr.",name:"Mehmet",middleName:"Cuneyt",surname:"Ozmen",slug:"mehmet-ozmen",fullName:"Mehmet Ozmen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/89721/images/7289_n.jpg",biography:null,institutionString:null,institution:{name:"Gazi University",country:{name:"Turkey"}}},{id:"243698",title:"M.D.",name:"Xiaogang",middleName:null,surname:"Wang",slug:"xiaogang-wang",fullName:"Xiaogang Wang",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/243698/images/system/243698.png",biography:"Dr. Xiaogang Wang, a faculty member of Shanxi Eye Hospital specializing in the treatment of cataract and retinal disease and a tutor for postgraduate students of Shanxi Medical University, worked in the COOL Lab as an international visiting scholar under the supervision of Dr. David Huang and Yali Jia from October 2012 through November 2013. Dr. Wang earned an MD from Shanxi Medical University and a Ph.D. from Shanghai Jiao Tong University. Dr. Wang was awarded two research project grants focused on multimodal optical coherence tomography imaging and deep learning in cataract and retinal disease, from the National Natural Science Foundation of China. He has published around 30 peer-reviewed journal papers and four book chapters and co-edited one book.",institutionString:"Shanxi Eye Hospital",institution:{name:"Shanxi Eye Hospital",country:{name:"China"}}},{id:"242893",title:"Ph.D. Student",name:"Joaquim",middleName:null,surname:"De Moura",slug:"joaquim-de-moura",fullName:"Joaquim De Moura",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/242893/images/7133_n.jpg",biography:"Joaquim de Moura received his degree in Computer Engineering in 2014 from the University of A Coruña (Spain). In 2016, he received his M.Sc degree in Computer Engineering from the same university. He is currently pursuing his Ph.D degree in Computer Science in a collaborative project between ophthalmology centers in Galicia and the University of A Coruña. His research interests include computer vision, machine learning algorithms and analysis and medical imaging processing of various kinds.",institutionString:null,institution:{name:"University of A Coruña",country:{name:"Spain"}}},{id:"267434",title:"Dr.",name:"Rohit",middleName:null,surname:"Raja",slug:"rohit-raja",fullName:"Rohit Raja",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRZkkQAG/Profile_Picture_2022-05-09T12:55:18.jpg",biography:null,institutionString:null,institution:null},{id:"294334",title:"B.Sc.",name:"Marc",middleName:null,surname:"Bruggeman",slug:"marc-bruggeman",fullName:"Marc Bruggeman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/294334/images/8242_n.jpg",biography:"Chemical engineer graduate, with a passion for material science and specific interest in polymers - their near infinite applications intrigue me. \n\nI plan to continue my scientific career in the field of polymeric biomaterials as I am fascinated by intelligent, bioactive and biomimetic materials for use in both consumer and medical applications.",institutionString:null,institution:null},{id:"244950",title:"Dr.",name:"Salvatore",middleName:null,surname:"Di Lauro",slug:"salvatore-di-lauro",fullName:"Salvatore Di Lauro",position:null,profilePictureURL:"https://intech-files.s3.amazonaws.com/0030O00002bSF1HQAW/ProfilePicture%202021-12-20%2014%3A54%3A14.482",biography:"Name:\n\tSALVATORE DI LAURO\nAddress:\n\tHospital Clínico Universitario Valladolid\nAvda Ramón y Cajal 3\n47005, Valladolid\nSpain\nPhone number: \nFax\nE-mail:\n\t+34 983420000 ext 292\n+34 983420084\nsadilauro@live.it\nDate and place of Birth:\nID Number\nMedical Licence \nLanguages\t09-05-1985. Villaricca (Italy)\n\nY1281863H\n474707061\nItalian (native language)\nSpanish (read, written, spoken)\nEnglish (read, written, spoken)\nPortuguese (read, spoken)\nFrench (read)\n\t\t\nCurrent position (title and company)\tDate (Year)\nVitreo-Retinal consultant in ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl. National Health System.\nVitreo-Retinal consultant in ophthalmology. Instituto Oftalmologico Recoletas. Red Hospitalaria Recoletas. Private practise.\t2017-today\n\n2019-today\n\t\n\t\nEducation (High school, university and postgraduate training > 3 months)\tDate (Year)\nDegree in Medicine and Surgery. University of Neaples 'Federico II”\nResident in Opthalmology. Hospital Clinico Universitario Valladolid\nMaster in Vitreo-Retina. IOBA. University of Valladolid\nFellow of the European Board of Ophthalmology. Paris\nMaster in Research in Ophthalmology. University of Valladolid\t2003-2009\n2012-2016\n2016-2017\n2016\n2012-2013\n\t\nEmployments (company and positions)\tDate (Year)\nResident in Ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl.\nFellow in Vitreo-Retina. IOBA. University of Valladolid\nVitreo-Retinal consultant in ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl. National Health System.\nVitreo-Retinal consultant in ophthalmology. Instituto Oftalmologico Recoletas. Red Hospitalaria Recoletas. \n\t2012-2016\n2016-2017\n2017-today\n\n2019-Today\n\n\n\t\nClinical Research Experience (tasks and role)\tDate (Year)\nAssociated investigator\n\n' FIS PI20/00740: DESARROLLO DE UNA CALCULADORA DE RIESGO DE\nAPARICION DE RETINOPATIA DIABETICA BASADA EN TECNICAS DE IMAGEN MULTIMODAL EN PACIENTES DIABETICOS TIPO 1. Grant by: Ministerio de Ciencia e Innovacion \n\n' (BIO/VA23/14) Estudio clínico multicéntrico y prospectivo para validar dos\nbiomarcadores ubicados en los genes p53 y MDM2 en la predicción de los resultados funcionales de la cirugía del desprendimiento de retina regmatógeno. Grant by: Gerencia Regional de Salud de la Junta de Castilla y León.\n' Estudio multicéntrico, aleatorizado, con enmascaramiento doble, en 2 grupos\nparalelos y de 52 semanas de duración para comparar la eficacia, seguridad e inmunogenicidad de SOK583A1 respecto a Eylea® en pacientes con degeneración macular neovascular asociada a la edad' (CSOK583A12301; N.EUDRA: 2019-004838-41; FASE III). Grant by Hexal AG\n\n' Estudio de fase III, aleatorizado, doble ciego, con grupos paralelos, multicéntrico para comparar la eficacia y la seguridad de QL1205 frente a Lucentis® en pacientes con degeneración macular neovascular asociada a la edad. (EUDRACT: 2018-004486-13). Grant by Qilu Pharmaceutical Co\n\n' Estudio NEUTON: Ensayo clinico en fase IV para evaluar la eficacia de aflibercept en pacientes Naive con Edema MacUlar secundario a Oclusion de Vena CenTral de la Retina (OVCR) en regimen de tratamientO iNdividualizado Treat and Extend (TAE)”, (2014-000975-21). Grant by Fundacion Retinaplus\n\n' Evaluación de la seguridad y bioactividad de anillos de tensión capsular en conejo. Proyecto Procusens. Grant by AJL, S.A.\n\n'Estudio epidemiológico, prospectivo, multicéntrico y abierto\\npara valorar la frecuencia de la conjuntivitis adenovírica diagnosticada mediante el test AdenoPlus®\\nTest en pacientes enfermos de conjuntivitis aguda”\\n. National, multicenter study. Grant by: NICOX.\n\nEuropean multicentric trial: 'Evaluation of clinical outcomes following the use of Systane Hydration in patients with dry eye”. Study Phase 4. Grant by: Alcon Labs'\n\nVLPs Injection and Activation in a Rabbit Model of Uveal Melanoma. Grant by Aura Bioscience\n\nUpdating and characterization of a rabbit model of uveal melanoma. Grant by Aura Bioscience\n\nEnsayo clínico en fase IV para evaluar las variantes genéticas de la vía del VEGF como biomarcadores de eficacia del tratamiento con aflibercept en pacientes con degeneración macular asociada a la edad (DMAE) neovascular. Estudio BIOIMAGE. IMO-AFLI-2013-01\n\nEstudio In-Eye:Ensayo clínico en fase IV, abierto, aleatorizado, de 2 brazos,\nmulticçentrico y de 12 meses de duración, para evaluar la eficacia y seguridad de un régimen de PRN flexible individualizado de 'esperar y extender' versus un régimen PRN según criterios de estabilización mediante evaluaciones mensuales de inyecciones intravítreas de ranibizumab 0,5 mg en pacientes naive con neovascularización coriodea secunaria a la degeneración macular relacionada con la edad. CP: CRFB002AES03T\n\nTREND: Estudio Fase IIIb multicéntrico, randomizado, de 12 meses de\nseguimiento con evaluador de la agudeza visual enmascarado, para evaluar la eficacia y la seguridad de ranibizumab 0.5mg en un régimen de tratar y extender comparado con un régimen mensual, en pacientes con degeneración macular neovascular asociada a la edad. CP: CRFB002A2411 Código Eudra CT:\n2013-002626-23\n\n\n\nPublications\t\n\n2021\n\n\n\n\n2015\n\n\n\n\n2021\n\n\n\n\n\n2021\n\n\n\n\n2015\n\n\n\n\n2015\n\n\n2014\n\n\n\n\n2015-16\n\n\n\n2015\n\n\n2014\n\n\n2014\n\n\n\n\n2014\n\n\n\n\n\n\n\n2014\n\nJose Carlos Pastor; Jimena Rojas; Salvador Pastor-Idoate; Salvatore Di Lauro; Lucia Gonzalez-Buendia; Santiago Delgado-Tirado. Proliferative vitreoretinopathy: A new concept of disease pathogenesis and practical\nconsequences. Progress in Retinal and Eye Research. 51, pp. 125 - 155. 03/2016. DOI: 10.1016/j.preteyeres.2015.07.005\n\n\nLabrador-Velandia S; Alonso-Alonso ML; Di Lauro S; García-Gutierrez MT; Srivastava GK; Pastor JC; Fernandez-Bueno I. Mesenchymal stem cells provide paracrine neuroprotective resources that delay degeneration of co-cultured organotypic neuroretinal cultures.Experimental Eye Research. 185, 17/05/2019. DOI: 10.1016/j.exer.2019.05.011\n\nSalvatore Di Lauro; Maria Teresa Garcia Gutierrez; Ivan Fernandez Bueno. Quantification of pigment epithelium-derived factor (PEDF) in an ex vivo coculture of retinal pigment epithelium cells and neuroretina.\nJournal of Allbiosolution. 2019. ISSN 2605-3535\n\nSonia Labrador Velandia; Salvatore Di Lauro; Alonso-Alonso ML; Tabera Bartolomé S; Srivastava GK; Pastor JC; Fernandez-Bueno I. Biocompatibility of intravitreal injection of human mesenchymal stem cells in immunocompetent rabbits. Graefe's archive for clinical and experimental ophthalmology. 256 - 1, pp. 125 - 134. 01/2018. DOI: 10.1007/s00417-017-3842-3\n\n\nSalvatore Di Lauro, David Rodriguez-Crespo, Manuel J Gayoso, Maria T Garcia-Gutierrez, J Carlos Pastor, Girish K Srivastava, Ivan Fernandez-Bueno. A novel coculture model of porcine central neuroretina explants and retinal pigment epithelium cells. Molecular Vision. 2016 - 22, pp. 243 - 253. 01/2016.\n\nSalvatore Di Lauro. Classifications for Proliferative Vitreoretinopathy ({PVR}): An Analysis of Their Use in Publications over the Last 15 Years. Journal of Ophthalmology. 2016, pp. 1 - 6. 01/2016. DOI: 10.1155/2016/7807596\n\nSalvatore Di Lauro; Rosa Maria Coco; Rosa Maria Sanabria; Enrique Rodriguez de la Rua; Jose Carlos Pastor. Loss of Visual Acuity after Successful Surgery for Macula-On Rhegmatogenous Retinal Detachment in a Prospective Multicentre Study. Journal of Ophthalmology. 2015:821864, 2015. DOI: 10.1155/2015/821864\n\nIvan Fernandez-Bueno; Salvatore Di Lauro; Ivan Alvarez; Jose Carlos Lopez; Maria Teresa Garcia-Gutierrez; Itziar Fernandez; Eva Larra; Jose Carlos Pastor. Safety and Biocompatibility of a New High-Density Polyethylene-Based\nSpherical Integrated Porous Orbital Implant: An Experimental Study in Rabbits. Journal of Ophthalmology. 2015:904096, 2015. DOI: 10.1155/2015/904096\n\nPastor JC; Pastor-Idoate S; Rodríguez-Hernandez I; Rojas J; Fernandez I; Gonzalez-Buendia L; Di Lauro S; Gonzalez-Sarmiento R. Genetics of PVR and RD. Ophthalmologica. 232 - Suppl 1, pp. 28 - 29. 2014\n\nRodriguez-Crespo D; Di Lauro S; Singh AK; Garcia-Gutierrez MT; Garrosa M; Pastor JC; Fernandez-Bueno I; Srivastava GK. Triple-layered mixed co-culture model of RPE cells with neuroretina for evaluating the neuroprotective effects of adipose-MSCs. Cell Tissue Res. 358 - 3, pp. 705 - 716. 2014.\nDOI: 10.1007/s00441-014-1987-5\n\nCarlo De Werra; Salvatore Condurro; Salvatore Tramontano; Mario Perone; Ivana Donzelli; Salvatore Di Lauro; Massimo Di Giuseppe; Rosa Di Micco; Annalisa Pascariello; Antonio Pastore; Giorgio Diamantis; Giuseppe Galloro. Hydatid disease of the liver: thirty years of surgical experience.Chirurgia italiana. 59 - 5, pp. 611 - 636.\n(Italia): 2007. ISSN 0009-4773\n\nChapters in books\n\t\n' Salvador Pastor Idoate; Salvatore Di Lauro; Jose Carlos Pastor Jimeno. PVR: Pathogenesis, Histopathology and Classification. Proliferative Vitreoretinopathy with Small Gauge Vitrectomy. Springer, 2018. ISBN 978-3-319-78445-8\nDOI: 10.1007/978-3-319-78446-5_2. \n\n' Salvatore Di Lauro; Maria Isabel Lopez Galvez. Quistes vítreos en una mujer joven. Problemas diagnósticos en patología retinocoroidea. Sociedad Española de Retina-Vitreo. 2018.\n\n' Salvatore Di Lauro; Salvador Pastor Idoate; Jose Carlos Pastor Jimeno. iOCT in PVR management. OCT Applications in Opthalmology. pp. 1 - 8. INTECH, 2018. DOI: 10.5772/intechopen.78774.\n\n' Rosa Coco Martin; Salvatore Di Lauro; Salvador Pastor Idoate; Jose Carlos Pastor. amponadores, manipuladores y tinciones en la cirugía del traumatismo ocular.Trauma Ocular. Ponencia de la SEO 2018..\n\n' LOPEZ GALVEZ; DI LAURO; CRESPO. OCT angiografia y complicaciones retinianas de la diabetes. PONENCIA SEO 2021, CAPITULO 20. (España): 2021.\n\n' Múltiples desprendimientos neurosensoriales bilaterales en paciente joven. Enfermedades Degenerativas De Retina Y Coroides. SERV 04/2016. \n' González-Buendía L; Di Lauro S; Pastor-Idoate S; Pastor Jimeno JC. Vitreorretinopatía proliferante (VRP) e inflamación: LA INFLAMACIÓN in «INMUNOMODULADORES Y ANTIINFLAMATORIOS: MÁS ALLÁ DE LOS CORTICOIDES. 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\r\n\tPollution is caused by a wide variety of human activities and occurs in diverse forms, for example biological, chemical, et cetera. In recent years, significant efforts have been made to ensure that the environment is clean, that rigorous rules are implemented, and old laws are updated to reduce the risks towards humans and ecosystems. However, rapid industrialization and the need for more cultivable sources or habitable lands, for an increasing population, as well as fewer alternatives for waste disposal, make the pollution control tasks more challenging. Therefore, this topic will focus on assessing and managing environmental pollution. It will cover various subjects, including risk assessment due to the pollution of ecosystems, transport and fate of pollutants, restoration or remediation of polluted matrices, and efforts towards sustainable solutions to minimize environmental pollution.
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",annualVolume:11967,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/39.jpg",editor:{id:"137040",title:"Prof.",name:"Jose",middleName:null,surname:"Navarro-Pedreño",fullName:"Jose Navarro-Pedreño",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRAXrQAO/Profile_Picture_2022-03-09T15:50:19.jpg",institutionString:"Miguel Hernández University of Elche, Spain",institution:null},editorTwo:null,editorThree:null,editorialBoard:[{id:"177015",title:"Prof.",name:"Elke Jurandy",middleName:null,surname:"Bran Nogueira Cardoso",fullName:"Elke Jurandy Bran Nogueira Cardoso",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRGxzQAG/Profile_Picture_2022-03-25T08:32:33.jpg",institutionString:"Universidade de São Paulo, Brazil",institution:null},{id:"211260",title:"Dr.",name:"Sandra",middleName:null,surname:"Ricart",fullName:"Sandra Ricart",profilePictureURL:"https://mts.intechopen.com/storage/users/211260/images/system/211260.jpeg",institutionString:null,institution:{name:"University of Alicante",institutionURL:null,country:{name:"Spain"}}}]},{id:"40",title:"Ecosystems and Biodiversity",keywords:"Ecosystems, Biodiversity, Fauna, Taxonomy, Invasive species, Destruction of habitats, Overexploitation of natural resources, Pollution, Global warming, Conservation of natural spaces, Bioremediation",scope:"