Studies of green corrosion inhibitor reported.
\r\n\tThis book aims to expose the recent advances in the research and development of chemical and biochemical processes to obtain bio-based chemical compounds and fuels from glycerol.
\r\n\r\n\tChapters dealing with the synthesis and characterization of catalysts (single and mixed hydroxides and oxides, supported catalysts, zeolites, heteropolyacids, pillared-clays, and metal-organic frameworks) and biocatalysts (novel microbial and fungi cultures, immobilized cells, immobilized enzymes, and nanobiocatalysts) to carry out the conversion of glycerol, as well as their testing in discontinuous and continuous stirred reactors, fixed-bed, fluidized-bed, trickle-bed, bubble column, airlift and membrane (bio)reactors are welcome.
\r\n\r\n\tThe book will comprise, but will not be limited to, the homogeneous and heterogeneous chemical reactions of glycerol such as dehydration, hydrogenolysis, partial oxidation, steam- and dry-reforming, glycerol to hydrocarbon fuels and aromatics, (trans)esterification, etherification, halogenation, ammoxidation, as well as supercritical, and photocatalytic processes.
\r\n\r\n\tAdditionally, we hope to cover the bioprocessing of glycerol, including microbial and fungal fermentation and enzymatic reactions to obtain C2-C4 alcohols, diols, hydrogen, methane, organic acids, dihydroxyacetone, biopolymers, and others.
\r\n\tThe book will also deal with the engineering aspects of glycerol processing, such as chemical equilibrium of glycerol reactions, reaction kinetics, (bio)reactor modeling, as well as process simulation and optimization of process variables and reactors.
All next years and decades form an epoch of using smart systems. What about the usefulness of smart systems for prediction and rationale of preventive measures against possible threats? To answer this question, we address to some definitions.
\nAccording to ISO Guide 73, in general, case risk is defined as the effect of uncertainty on objectives. An effect is a deviation from the expected—positive and/or negative. Objectives can have different aspects (such as financial, health and safety, and environmental goals) and can be applied at different levels (such as strategic, organization-wide, project, product, and process). Risk is often characterized by reference to potential events and consequences or a combination of these. Risk may be estimated by a probability of potential events, leading to effects considering consequences. The chapter, including examples, is focused on events leading to losses of system integrity (often with negative consequences). But it does not limit a generality of proposed approaches.
\nAccording to ISO/IEC/IEEE 15288 “Systems and software engineering—System life cycle processes,” a system is a combination of interacting elements organized to achieve one or more stated purposes. An enabling system is a system that supports a system of interest during its life cycle stages but does not necessarily contribute directly to its function during operation. A system of systems (SoS) is a system of interest whose elements are themselves systems. A SoS brings together a set of systems for a task that none of the systems can accomplish on its own. Each constituent system keeps its own management, goals, and resources while coordinating within the SoS and adapting to meet SoS goals. The research covers systems defined in itself as “smart” system or using “smart” systems (see Figure 1).
\nTo the definition of “smart system” in a system.
For modern or perspective system or for a system of systems from the point of view of prediction and rationale of preventive measures against possible threats, the “smart” systems are and will be used as the systems in itself or as system elements or enabling systems. In a general case, “smart” is a mnemonic acronym, giving criteria to guide in the setting of objectives, and “smart systems” are defined as miniaturized devices that incorporate functions of sensing, actuation, and control (www.wikipedia.org, www.thefullwiki.org).
\nDeveloping existing researches [1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17], this manuscript includes correct probabilistic interpretation of risk prediction effectively using “smart” systems, some original basic probabilistic models for risk prediction, the improvement of existing risk control concept, and approaches for solving some problems of industrial safety for coal branch.
\nBecause “smart” possibilities allow to forecast a future, we should view probabilistic vision of event prediction, its scientific interpretation, and, unfortunately, some existing illusory vision. Here, from the scientific point of view for anticipating dangerous development of events, it is difficult to construct an adequate probability distribution function (PDF) [1, 2, 3, 4] of time between losses of system integrity. Damage may be to some extent estimated on practice (we will consider that the deviations in estimations can reach 100%). Therefore, leaving an estimation of a possible damage out of the work, we will stop on researches of a probabilistic component of risk. What deviations in risk predictions are possible here? To answer this question, it is necessary to understand typical metrics and engineering methods of risk predictions, in definition and concept to use “admissible risk,” and then to compare various variants.
\nIn practice probabilistic estimations of system integrity losses are quite often carried out by the frequency of emergencies or any adverse events. For example, with reference to safety, it can be frequencies of different danger threats influences, leading to a damage. That is, frequency replaces estimations of probability (risk to lose integrity of system during prognostic period). It is correct? From probability theory it is known that for defined PDF one of its characteristics is the mathematical expectation (Texp.). In turn, for PDF of time between losses of system integrity, the mathematical expectation is the mean time between neighboring losses of system integrity Texp., and moreover the frequency
For the same λ, a probability that event has occurred can be equal to 0.00 for approximation by deterministic PDF and 0.36 for exponential PDF approximation.
Often today, engineers prefer exponential PDF: R(t, λ) = 1 – exp. (−λ∙t). If, for example, for 1 year of prognostic period to put λ about 10−3 times in a year or less, then under Taylor’s expansion R(t, λ) ≈ λ∙t with accuracy o(λ2∙t2). And, if t = 1 year, the absolute value of frequency practically coincides with the value of probability. But if value λ∙t increases, it is capable to exceed 1 and by definition generally cannot be perceived as probability. Resume: focusing on probability is correct from the point of view of universal risk metric. And, focusing on frequency may be incorrect if λ∙t is approximately more than 10−3.
\nThe special importance has the concept of “admissible risk.” The matter is that there should be a result of the consent of all parties involved in unsafe business on condition that it does not ruin business; by all it is unequivocally estimated and interpreted (not excluding emergencies) and is scientifically proven. In practice frequently the “admissible risk” is interpreted as “border strip,” i.e., it is supposed that if it does not cross this “border strip,” the system integrity cannot be lost. But in reality it is not so! The residual risk always remains. In operation research the similar restrictions are considered as a starting point for the decision of synthesis problems, connected with searching effective preventive measures of system integrity in life cycle. The complex use of these measures promotes in retaining the risk on the admissible level. It is the typical approach which should work correctly. And how does it work in practice?
\nHere, it is to quite pertinently address the developed form of the quantitative requirements, connected with the level of admissible risks. The elementary forms of requirements are:
“A frequency λ of system integrity losses should not exceed admissible level λadm.”
“Probability to lose integrity of system during time Treq should not exceed admissible level Radm. (Treq).”
Their combination.
What engineering explanations occur in practice? They are as follows:
If the limitation on the admissible level of probability Radm. (Treq) is set, it means that crossing “border strip” should not occur on an interval of time from 0 to Treq. For exponential approximations there is an unequivocal functional dependence: λadm. = − ln(1- Radm. (Treq)). That is, this dependence means that a given value of admissible probability Radm. (Treq) corresponds unequivocally with a value of the maximum frequency of system integrity losses.
If the limitation on the admissible level of maximum frequency of system integrity losses λadm. is set, it means that for exponential approximations the function of probability from time t is considered: R(t, λadm.) = 1 – exp. (−λadm.∙t). That is, this is the same “border strip” but in the form of the function from t and without an obvious binding to value Treq. This level of limitation by function Radm. (Treq) is logically to interpret also as “admissible” for the period of time from 0 to t. Admissible risk in the point of probability Padm. (treq.) for time treq. May be prolonged on the level of PDF by exponential distribution and the admissible frequency of system integrity losses λ = − ln(1- Рadm. (treq.)). It is convenient, but is it adequate? In reality a vision about exponential PDF for behavior of “smart” system may be roughly erroneous (see Figure 3).
About erroneous vision of exponential PDF approximation instead of more adequate approximation.
Despite obvious incompleteness of the elementary forms of requirements to “admissible risks” (in reality, only the limitations in one or several points) and the absence of interrelations with a kind of real PDF of time between losses of system integrity (depending from many parameters: structure of system, heterogeneity of threats, different measures of counteraction to threats, etc.), these forms have got accepted by engineering community. In the further statement of the work, we will be guided by these elementary forms of requirements to “admissible risks.” They also allow to extract latent knowledge from the results of adequate probabilistic modeling.
\nToday, specifications of safety in different fields characterize a frequency
Accordingly, there is an important question: what frequencies of system integrity losses should be used for risk predictions and where does it take? If these are only the frequencies of emergencies, the predicted risks will be essentially underestimated! These final frequencies are output instead of input data for modeling. Estimate, please: if to be guided by these frequencies and to consider that 50–70% of failures are the result of “human factor,” it should mean that the frequency of critical errors from “human factor” on systems is about one time in thousand years! However, that is not so in real life! Errors are committed much more often. But they are under control, and the majority of them is in due time corrected. As consequence of these counteraction measures, required system integrity (including safety) is reached. The answer arises obviously: the frequency
Consideration of “smart” system possibilities for proactive diagnostics of system integrity, monitoring of conditions, and recovering the lost integrity allows to create more adequate PDF for risk predictions. In Figure 4 the limitations to admissible risks, fragment of exponential, and an adequate PDF of time between losses of system integrity with identical frequency of system integrity losses are demonstrated. The errors in comparison with vision in Figure 3 are noted.
\nThe possible variants of correlations of the limitations to admissible risks, exponential, and an adequate PDF of time between losses of system integrity with identical frequency of system integrity losses λ.
An example when all requirements to admissible risk are met is presented on Figure 5. It is the right understanding of probabilistic vision of event prediction with scientific interpretation considering situations in Figure 4.
\nAll requirements to admissible risk are met for an adequate PDF of time between losses of system integrity.
Considering possibilities of “smart” systems, two general technologies of providing protection in different spheres are described: proactive periodical diagnostics of system integrity (technology 1) and additionally monitoring between diagnostics (technology 2) including recovery of integrity [2, 3, 6, 7, 8, 9, 10]. These models allow to create more adequate PDF of time before the next event of the lost integrity.
\nTechnology 1 is based on proactive diagnostics of system integrity that are carried out periodically to detect danger occurrences into a system or consequences of negative influences. The lost system integrity can be detected only as a result of diagnostics, after which the recovery of integrity is started. Dangerous influence on system is acted step by step: at first a danger occurrence into a system and then after its activation begins to influence. System integrity cannot be lost before an occurred danger is activated. A danger is considered to be realized only after a danger has activated and influenced on a system. Otherwise, the danger will be detected and neutralized during the next diagnostic.
\nNote: it is supposed that used diagnostic tools allow to provide system integrity recovery after revealing of danger occurrences into a system or consequences of influences.
\nTechnology 2, unlike the previous one, implies that operators alternating each other trace system integrity between diagnostics. In case of detecting a danger, an operator recovers system integrity (ways of dangers removing and system recovery are the same as for technology 1). Faultless operator’s actions provide a neutralization of a danger. When a complex diagnostic is periodically performed, this time operators are alternated. An occurrence of a danger is possible only if an operator makes an error, but a dangerous influence occurs if the danger is activated before the next diagnostic.
\nThe probability of system operation with required safety and quality within the given prognostic period (i.e., probability of success) may be estimated as a result of using the next models for technologies 1 and 2. Assumption: for all time input characteristic, the probability distribution functions exist. Risk R(Treq) to lose integrity (safety, quality, or separate property, e.g., reliability), i.e., to be though one time in “red” range during period Treq, is addition to 1 for probability P(Treq) of providing system integrity (“probability of success,” i.e., to be in “green” or “yellow” ranges all period Treq). R(Treq) =1-P(Treq) considering consequences.
\nThe next variants for technologies 1 and 2 are possible: variant 1—the given prognostic period Treq is less than established period between neighboring diagnostics (Treq < Tbetw. + Tdiag); variant 2—the prognostic period Treq is more than or equals to established period between neighboring diagnostics (Treq ≥ Tbetw. + Tdiag). Here, Tbetw. is the time between the end of diagnostic and the beginning of the next diagnostic, and Tdiag is the diagnostic time.
\nThe next formulas for PDF of time between the losses of system integrity are proposed [2, 3].
\nwhere Ωoccur(t) is the PDF of time between neighboring occurrences of danger (from the “green” to the “yellow” range), mathematical expectation Toccur = σ−1; Ωactiv(t) is the PDF of activation time of occurred danger (threat: from the first input at the “yellow” range to the first input in the “red” range), and mathematical expectation is β. The PDF Ωoccur(t) and Ωactiv(t) may be exponential (see rationale in [6]). For different threats a frequency of dangers for these PDF is the sum of frequencies of every kind of threats.
\nwhere N = [Тreq./(Тbetw. + Тdiag.)] may be real (for PDF) or the integer part (for estimation of deviations).
\nThe probability of providing system integrity within the given time P(1)(Tgiven) is defined by Eq. (1).
\nHere, A(τ) is the PDF of time between operator’s errors. A(τ) may be exponential PDF (see rationale in [6]).
\nwhere the probability of providing system integrity within the given time P(1)(Treq.) is defined by Eq. (3).
\nThe final clear analytical formulas for modeling are received by Lebesgue integration of expression (3).
\nThe models are applicable to the system presented as one element. The main result of such system modeling is a probability of providing system integrity or of losses of system integrity during the given period of time. If a probability for all points Тreq. from 0 to ∞ will be calculated, a trajectory of the PDF for each combined element depending on threats, periodic control, monitoring, and recovery time is automatically synthesized.
\nIn general case “smart” system operation always aims to provide reliable and timely producing the complete, valid and, if needed, confidential information for its proper further pragmatic use, including incorporate functions of sensing, actuation, and control. And, potential threats to “smart” system operation are influencing the used information (Figure 6).
\nPotential threat realization to “smart” system operation on the level of used information.
In general case a probabilistic space (
“The model of function performance by a complex system in conditions of unreliability of its components” (the measures: TMTBF is the mean time between failures; Prel.(Тgiven) is the probability of reliable operation of IS, composed by subsystems and system elements, during the given period Тgiven; and Pman(Тgiven) is the probability of providing faultless man’s actions during the given period Тgiven).
\n“The model complex of call processing” (the measures for the different dispatcher technologies (for unpriority call processing in a consecutive order for single-tasking processing mode, in a time-sharing order for multitasking processing mode; for priority technologies of consecutive call processing with relative and absolute priorities; for batch call processing; for combination of technologies above): the mean wait time in a queue; the mean full processing time, including the wait time; Ptim is the probability of well-timed processing during the given time; the relative portion of all well-timed processed calls; the relative portion of well-timed processed calls of those types for which the customer requirements are met Ctim).
\n“The model of entering into IS current data concerning new objects of application domain” (the measure: Pcompl is the probability that IS contains complete current information about the states of all objects and events).
\n“The model of information gathering” (the measure: Pactual. is the probability of IS information actuality on the moment of its use).
\n“The model of information analysis” (the measures: Pcheck is the probability of error absence after checking; the fraction of errors in information after checking; Pprocess is the probability of correct analysis results obtained; the fraction of unaccounted essential information).
\n“The model complex of dangerous influences on a protected system” (the measures: Pinf.l.(Тgiven) is the probability of required counteraction to dangerous influences from threats during the given period Тgiven).
\n“The model complex of an authorized access to system resources” (the measures: Pprot is the probability of providing system protection from an unauthorized access by means of barriers; Pconf. (Тgiven) is the probability of providing information confidentiality by means of all barriers during the given period Тgiven).
\nThese models, supported by different versions of software Complex for Evaluation of Information Systems Operation Quality, patented by Rospatent №2,000,610,272 (CEISOQ+), may be applied and improved for solving such system problems in “smart” system life cycle as rationale of quantitative system requirements to hardware, software, users, staff, and technologies; requirement analysis; estimation of project engineering decisions and possible danger; detection of bottlenecks; investigation of problems concerning potential threats to system operation and information security; testing, verification, and validation of “smart” system operation quality; rational optimization of “smart” system technological parameters; and rationale of projects and directions for effective system improvement and development.
\nThe basic ideas of correct integration of probabilistic metrics are based on a combination and development of the offered models [2, 3, 6, 7, 8, 9, 10]. For a complex system estimation with parallel or serial structure, new models can be generated by methods of probability theory. For this purpose in analogy with reliability, it is necessary to know a mean time between losses of integrity for each element. Let’s consider the elementary structure from two independent parallel elements that means logic connection “OR” or series elements that means logic connection “AND” (see Figure 7).
\nIllustration of system, combined from series (left) or parallel (right) elements.
The PDF of time between neighboring losses of ith element integrity is Вi(t) = Р (τi ≤ t); then:
\n(1) Time between losses of integrity for system combined from series connected independent elements is equal to a minimum from two times τi: failure of the first or second elements (i.e., the system goes into a state of lost integrity when either the first or second element integrity will be lost). For this case the PDF of time between losses of system integrity is defined by expression
\n(2) Time between losses of integrity for system combined from parallel connected independent elements (hot reservation) is equal to a maximum from two times τi: failure of the first or second elements (i.e., the system goes into a state of lost integrity when both the first and second element integrity will be lost). For this case the PDF of time between losses of system integrity is defined by expression
\nNote: The same approach is studied also by Prof. E. Ventcel (Russia) in 80th who has formulated the trying tasks for students.
\nThus, an adequacy of probabilistic models is reached by the consideration of real processes of control, monitoring, and element recovery for complex structure. Applying recurrently expressions (5)–(6), it is possible to create PDF of time between losses of integrity for any complex system with parallel and/or series structure.
\nThe known kind of the more adequate PDF allows to define accordingly mean time between neighboring losses of system integrity Texp. (may be calculated from this PDF as mathematical expectation) and a frequency λ of system integrity losses λ = 1/ Texp..
\nRisk to lose integrity (safety, quality, or separate property, e.g., reliability) is an addition to 1 for probability of providing system integrity (correct system operation or “probability of success”) R = 1−P. The formulas for probabilistic modeling technologies 1 and 2 and the proofs of them are proposed in [2, 3, 6].
\nAll these ideas are implemented by the software technologies of risk prediction for complex systems, for example, the “mathematical modeling of system life cycle processes,” “know-how” (registered by Rospatent №2,004,610,858), and “complex for evaluating quality of production processes” (patented by Rospatent №2,010,614,145) [8, 9].
\nThe purposed approach to improve existing risk control concept includes (see Figure 8) [11, 12, 13, 14, 15, 16, 17]:
Creation and perfection of probabilistic models for problem decision
Automatic combination and generation of new probabilistic models
Forming the storehouse of risk prediction knowledge
For storehouse, dozens of variants of the decision of typical industrial problems for risk control
The purposed approach to improve existing risk control concept.
For example,
Thus, the proposed improved that risk control concept can be useful to perform effectively functions: risk prediction; rationale of quantitative system requirements to hardware, software, users, staff, and technologies; requirement analysis; estimation of project engineering decisions and possible danger; detection of bottlenecks; investigation of problems concerning potential threats to operation of complex systems; validation of system operation quality; rational optimization of system parameters; and rationale of plans, projects, and directions for effective system utilization, improvement, and development. The expected pragmatic effect is as follows: it is possible to provide essential system quality and safety rise and/or avoid wasted expenses in system life cycle bases on the rational application of improved concept.
\nAs an example of effectively solving the problems of industrial safety, we consider an experience of the joint-stock company “Siberian Coal Energy Company (SUEK)” (see www.suek.com). SUEK is one of the world’s largest coal companies with production assets in Russia and a global trading network. SUEK delivers long-term value to shareholders at every stage of the value chain—mining, processing, transportation, and shipment—through port facilities, sales, and distribution (Figure 10). This value chain includes different SoS. In practice many SoS of SUEK use “smart” systems [11, 14].
\nThe SUEK value chain includes “smart” systems everywhere.
Below are the aspects researched:
Probabilistic analysis of the remote monitoring system (RMS) possibilities for increasing industrial safety of critical infrastructure safety (CIS).
Estimating in real time the mean residual time before the next parameter abnormalities considering the results of the control of equipment and technological process conformity to the set normative in real time.
For coal branch the developments of mine, buildings, and constructions should be equipped by a complex of systems and means that provide the organization and implementation of coal work safety and technological and productions control in normal and emergency conditions. This complex of systems and means should be integrated into multifunctional safety system (MFSS) with the following main functions:
Monitoring and prevention of conditions of occurrence of geodynamic, aerologic, and technogenic danger.
The control of technological process conformity to the set normative in real time.
Application of counteremergency protection systems.
The usual approaches to critical infrastructure safety (CIS) which have been developed in last dozen years, based on many respects on subjective safety estimations “on places”, have reached a high but not sufficient level of efficiency. For the account of interests of all interested parties and the further business development today, rethinking system possibilities of applied information technologies for increasing safety and extracting the innovative effects are not used fully till now.
\nSearch of cardinal directions of improving CIS, favorable to business and the state, has led to comprehension of sharp necessity and expediency of creation and implementation of remote monitoring system (RMS) that is an important part of MFSS. RMS transforms an internal information support of separate CIS in a mode of a needed transparency and wide availability of CIS state in real time for all interested and responsible parties. Along with it on the basis of rational RMS implementation, the transition from the existing subjective expert approach to the risk-based approach for critical infrastructure safety receives necessary information filling.
\nThe proposed probabilistic analysis of RMS operation in their influence on integral risks to lose system integrity is based on researching real remote monitoring systems implemented in Russia for oil and gas CIS. In application to composed and integrated CIS with RMS and without RMS, the earlier models, developed by authors, are used [1, 2, 3, 4, 5, 6, 7, 8, 9, 10]. The received results are applicable for an analytical rationale of system requirements to RMS, system definition of the balanced preventive measures of systems, and subsystem and element integrity support at limitations on resources and admissible risks.
\nRequirements to monitoring and prognosis for critical systems are established at the level of many international standards, for example, ISO 17359, ISO 13381–1, ISO 13379, IEC 61508–1 [18, 19, 20, 21], etc. Today, a monitoring of parameter conditions is carried out to increase reliability and industrial safety of critical systems, improve their health management, and provide predictive maintenance and operation efficiency. Here, critical systems are understood as objects of dangerous manufacture and the equipment, energy objects, power and transport systems, and others. Different data about current conditions of parameters become accessible in real time. So, for coal mine some of many dozens of heterogeneous parameters are for ventilation equipment (VE) (temperature of rotor and engine bearings, a current on phases, and voltage of stator) and for modular decontamination equipment (MDE) (vacuum in the pipeline, the expense and temperature of a metano-air mix in the pipeline before equipment, pressure in system of compressed air, etc.). Effects from RMS may be reached on the basis of gathering and analytical processing in real time the information on controllable parameters of objects monitored (see Figure 11). RMS is intended for a possibility of prediction, the prevention of possible emergencies, minimization of a role of human factor regarding control, and supervising functions. The role of RMS is defined by their functions, to the basic of which concern:
Remote continuous monitoring of CIS condition in real time (gathering data about key parameters of technological processes; gathering and processing data of industrial inspection, the information of technical condition and equipment diagnostics, and the information on the presence of failures and incidents; and results of system recovery, etc.)
Analytical data processing
Prediction of risks to lose object integrity
Display of parameter conditions and predictions with the necessary level of details
Example of reaction in real time.
In this subsection analytical decomposition and the subsequent integration of complex systems are used according to propositions above in Sections 1–4. Admissible conditions (ranges) of traced parameters for each element, the reservation possibilities, implemented technologies of the control, and recovery of integrity are considered.
\nRMS is intended for a possibility of prediction, the prevention of possible emergencies, minimization of a role of human factor regarding control, and supervising functions. It may be reached on the basis of gathering and analytical processing in real time the information on controllable parameters of objects monitored. For example, objects monitored for oil and gas CIS are the technological equipment and processes of extraction, transportation, refining, the personnel, systems, and means of safety support.
\nThe role of RMS is defined by their functions, to the basic of which concern:
Remote continuous monitoring of CIS condition in real time (gathering data about key parameters of technological processes; gathering and processing data of industrial inspection, the information of technical condition and equipment diagnostics, and the information on the presence of failures and incidents; and results of system recovery, etc.)
Analytical data processing
Prediction of risks to lose CIS integrity
Display of CIS conditions and predictions with the necessary level of details
Unlike the usual control which is carried out at enterprises (when the state supervising body in the field of industrial safety and frequently also the enterprise/holding bodies of the industrial safety control receive the information only upon incident or failure, not possessing the actual information about deviations at an initial stage when still it is possible to prevent failure), RMS translates the control, a transparency of CIS conditions, the important real-time information (about the facts and predictions), and also necessity of proper response to critical deviations for absolutely new time scale characterized as the scale of real time, measured by seconds-minutes.
\nEffects from the remote control can be reached only when quality of RMS operation is provided. It means that it is reliable and timely producing the complete, valid, and, if needed, confidential information by RMS.
\nGenerally, system analysis of RMS operation consists in evaluation of reliability, timeliness, completeness, validity, and confidentiality of the used information. In special cases for compound subsystems and system elements, not all measures may be used. For example, for a subsystem of information security enough to use the measures to evaluate protection from an unauthorized access and information confidentiality during the given time period. Dependence of the purposes of researching RMS can be decomposed to the level of compound subsystems and separate elements (see Figure 6).
\nIn this case according to the system engineering principles, the operation quality of every component should be evaluated.
\nFor evaluating integral RMS operation quality, the next measure is proposed: the probability of providing reliable and timely representation of the complete, valid, and confidential information during the given time (РRMS(Тgiven)).
\nIn general case
\nwhere all measures are calculated by the models proposed in Section 2.
\nFor complex structures the ideas of combination of the models is proposed in [15]. It allows in an automatic mode to generate new models at the expense that there is possible evaluation of the measures above.
\nWhen not all system elements and subsystems are captured by RMS capabilities, two subsystems, operated in different time scales, are cooperated in the CIS. A part of CIS, captured RMS, is served in real time, and the other part is in a usual time scale (with information gathering by a principle “as it is possible to receive”). In many critical situations, this usual time scale cannot be characterized as adequate to a reality. With the use of the offered approach, the system with usual control (UC), used for CIS, i.e., without RMS application, can be estimated. Generally, the analyzed critical infrastructure is presented as a combination “System+RMS” and usual “System without RMS.” And, “System+RMS” is a combination of “Structure for RMS” and “RMS” (see Figure 12). For these systems some measures of the information delivery may not answer requirements of real time—“System+RMS” because RMS operation quality is inadequate and “System without RMS” without RMS.
\nDecomposition of analyzed critical infrastructure to fill influence of RMS.
All the great number of the factors characterizing threats to analyzed critical infrastructure is considered as 100%, and total frequency of dangerous deviations is designated through λ∑. Frequency of potentially dangerous deviations traced by “System + RMS” is designated (λRMS). Frequency of occurrence of other potentially dangerous deviations which are not traced by RMS (i.e., for “System without RMS”) is designated (λ∑ − λRMS).
\nFor “System + RMS” the RMS operation quality during the time of prediction Тgiven is evaluated by probability РRMS(Тgiven). And, the risk of critical deviation for safety during the time of prediction Тgiven, designated as RRMS(Тgiven), can be evaluated by the earlier methods [2, 3, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17]. For the usual “System without RMS,” the same measures РUC(Тgiven) and RUC(Тgiven) can be used with specified value of input for probabilistic modeling.
\nThen, in general form, the risk R(Тgiven) to lose integrity for analyzed critical infrastructure during the time of prediction Тgiven can be evaluated by the formula:
\nwhere expression in square brackets is a probability of successful operation of analyzed critical infrastructure. Depending on the made risk definition in special cases, it can be interpreted as probability of safe or reliable operation or probability of norm observance for critical parameters of the equipment or others in the conditions of associated potential threats. The case λ∑ = λRMS means full capture of critical infrastructure by RMS capabilities.
\nUnfortunately, in the world the universal approach to adequate prognosis of the future parameter conditions on the basis of current data is not created yet. The uncertainty level is too high. Nevertheless, in practice for each concrete case, subjective expert estimations, regression analysis of collected data, and simulation are often used. And, probabilistic models applied in some cases contain many simplifications, and they frequently do not consider an infrastructure of complex systems, heterogeneity of threats, distinctions in technologies of the control, and recovery of integrity for various elements of these systems [2, 3]. The same aspects and also rarity of many random events (with some exceptions) do an ineffective statistical estimation of residual time before the next parameter abnormalities. At the same time, scientifically proven prognosis of a residual time resources is necessary for acceptance of preventive measures on timely elimination of the abnormality reasons. The above-stated characterizes an actuality of this and similar researches for different industrial areas [11, 12, 13, 14, 15, 16, 17].
\nTraced conditions of parameters are data about a condition before and on the current moment of time, but always the future is more important for all. With the use of current data, responsible staff (mechanics, technologists, engineers, etc.) should know about admissible time for work performance to maintain system operation. Otherwise, because of ignorance of a residual time resource before abnormality, the necessary works are not carried out. That is, because of ignorance of this residual time, measures for prevention of negative events after parameter abnormalities (failures, accidents, damages, and/or the missed benefit because of equipment time out) are not undertaken. And, on the contrary, knowing residual time before abnormality, these events may be avoided, or the system may be maintained accordingly. For monitored critical system, the probabilistic method to estimate the mean residual time before the next parameter abnormalities for each element and whole system is proposed.
\nBy principles of system engineering (e.g., according to ISO/IEC/IEEE 15288), the complex system is decomposed to compound subsystems and elements with formal definition of states (see Figure 13).
\nExample of system decomposition.
For every valuable subsystem (element), monitored parameters are chosen, and for each parameter, the ranges of possible values of conditions are established: “In working limits,” “Out of working range, but inside of norm,” and “Abnormality” (interpreted similarly light signals (“green,” “yellow,” “red”) (see Figure 14). The condition “Abnormality” characterizes a threat to lose system integrity (on the logic level, this range “Abnormality” may be interpreted analytically as failure, fault, unacceptable risk or quality, etc.).
\nElementary ranges for parameter conditions.
For avoiding the possible crossing of a border of “Abnormality,” a prediction of residual time, which is available for preventive measures, according to gathered data about parameter condition fluctuations considering ranges, should be carried out. For prediction the following are proposed: (1) a choice of probabilistic models for construction (PDF of time before the next abnormality for one element (“black box”)), (2) development of the algorithm of generation (PDF of time before the next abnormality for complex system), and 3) formalization of calculative methods of estimating the mean residual time before the next parameter abnormalities for monitored critical system.
\nThe method allows to estimate residual time before the next parameter abnormality (i.e., time before the first next coming into “red” range) [14].
\nThe method allows to estimate residual time before the next parameter abnormality Tresid(1) for a given admissible risk Radm.(Treq) to lose integrity. The estimated Tresid(1) is the solution t0 of equation:
\nconcerning of unknown parameter t, i.e., Tresid(1) = t0.
\nHere, R(Toccur, t, Tbetw, Tdiag, Тerr., Treq.) is the risk to lose integrity; it is addition to 1 for probability P(Treq) of providing system integrity (“probability of success”), and for calculations formulas (1)–(7) are used (see SubSection 3.1 of this article). So, for exponential PDF, formula (1) transforms into formula.
\nThis formula is used for Eq. (7).
\nToccur is the mathematical expectation of PDF Ωoccur (τ); it is defined by parameter statistics of transition from “green” into “yellow” range (see Figure 3). The other parameters Tbetw and Tdiag in formula (7) are known. The main practical questions are as follows: what about Treq. and what about the given admissible risk Radm.(Treq)? For answering we can use the properties of function R(Toccur, t, Tbetw, Tdiag, Тerr., Treq.):
If parameter t increases from 0 to ∞ for the same another parameters, the function R(…, t, …) is monotonously decreasing from 1 to 0, i.e., if the mean activation time of occurred danger (threat: from the first input at the “yellow” range to the first input in the “red” range) is bigger, to lose integrity is less.
If parameter Treq increases from 0 to ∞ for the same other parameters, the function R(…,Treq) is monotonously increasing from 0 to 1, i.e., for large Treq risk approaches to 1.
It means that the such maximal x exists when t = x and Treq. = x and 0 < R(Toccur, x, Tbetw, Tdiag, Тerr., x) < 1. That is, the residual time before the next parameter abnormality (i.e., time before the first next coming into “red” range) is equal to the defined x with the confidence level of admissible risk R(Toccur, x, Tbetw, Tdiag, Тerr., x).
\nFor example, if Toccur = 100, Tbetw = 8 hours, Tdiag = 1 hour, Тerr. = 0, and Radm. = 0.05, unknown x is defined from equation, considering (1), (7):
\nSo, if Toccur = 100 days, for Radm. = 0.01 residual time x ≈ 2.96 weeks (considering decisions of recovery problems of integrity every 8 hours).
\nThe method is implemented by RMS. At once after crossing “yellow” border from “green,” the automatic prediction of the mean residual time before the next parameter abnormalities (from the first input at the “yellow” range to the first input in the “red” range) is displayed (see Figure 15).
\nExample of residual time and comments.
Adequate reaction of responsible staff in real time is transparent for all interested parties.
\nSome effects from the proposed adequate probabilistic methods and technologies of RMS are estimated on the level of predicting risks to lose object safety (integrity) by PDF [16].
\nExample 5.3.1. According to statistics from multifunctional safety system (MFSS), a frequency of occurrence of the latent or obvious threats is equal to once a month, and an average time of development of threats (from occurrence of the first signs of a critical situation up to failure) is about 1 day. A work shift is equal to 8 hours. The system control is used once for work shift, and a mean duration of the system control is about 10 minutes (it is supposed that recovery of object integrity is expected also for 10 minutes). The workers (they may be mechanics, technologists, engineers, etc.) of medium-level and skilled workers are capable to revealing signs of a critical situation after their occurrence, and workers of the initial level of proficiency are incapable. Medium-level workers can commit errors on the average not more often once a month, and skilled workers are not more often once a year. How consideration of the qualification level influences on predicted risks to lose object safety for a year and for 10 years?
\nThe results of modeling. For workers of the initial level of proficiency, risks to lose object safety are near 1 (losses of integrity are inevitable). For workers of medium-level of proficiency, risk to lose object safety for a year is about 0.007 and for 10 years is about 0.067, and for skilled workers, risk equals to 0.0006 for a year and 0.0058 for 10 years because of effective monitoring using RMS possibilities.
\nExample 5.3.2. We will concentrate on the analysis of errors of skilled workers from the point of object safety. Raising adequacy of modeling, in addition to initial data of Example 5.3.1, we will consider that mean recovery time of the lost integrity of object equals to 1 day instead of 10 minutes [10]. What effect may be from risk prediction?
\nCalculated PDF fragment shows (see Figure 16) that risk to lose object safety increases from 0.0006 (for a year) to 0.0119 (for 20 years). Thus, the calculation from PDF mean time between neighboring losses of object safety Tmean equals to 493 years. That is, the frequency λ = 1/ Tmean of system safety losses is about 0.002 times a year. It is 6000 times less (!) in comparison with a primary frequency of occurrence of the latent or obvious threats (once a month). And, estimated Tmean is almost 500 times more in comparison with a primary mean time between errors of skilled workers (once a year). And, such effect can be reached at the expense of undertaken control measures, monitoring, and system recovering in case of revealing in time the signs of threat development. To the point, the frequency λ of system safety losses is extracted latent knowledge from PDF, built in a calculated form.
\nCalculated PDF fragment for Example 5.3.2.
If to compare with exponential approximation of PDF with the same frequency λ, the risk to lose object safety will grow from level 0.002 (for a year) to 0.04 (for 20 years). These are also extracted latent knowledge considering Taylor’s expansion R(t, λ) ≈ λ∙t (see Section 2). Difference is in 3.3–3.4 times more against adequate PDF. To feel, it is enough to ascertain that for created PDF the border of admissible risk 0.002 will be reached for 3 years, not for 1 year as for exponential PDF. That is, the real duration of effective object operation (i.e., without losses of safety) is three times more!
\nThis allowed to estimate operation of object as “black box,” described by characteristics of skilled workers. On dangerous manufacture critical operations are carried out by skilled workers in interaction with RMS (including reservation and supports of another). Formally, they operate as parallel elements with hot reservation. Thereby, the consideration of such interaction allows to increase adequacy of modeling. Let’s estimate risk to lose object safety for this variant (all input data for each from two parallel elements are the same that in Example 5.3.2).
\nCalculated PDF fragment shows (see Figure 17) that risk to lose object safety increases from 0.0000003 (for a year) to 0.00014 (for 20 years). Thus, the mean time between neighboring losses of object safety Tmean, calculated from known PDF, equals to 663 years. That is, the frequency λ of system safety losses is about 0.0015 times a year. It is 8000 times less (!) in comparison with a primary frequency of occurrence of the latent or obvious threats (once a month). And, at the expense of reservation estimated, Tmean is 34.5% longer in comparison with Tmean from Example 5.3.2.
\nCalculated PDF fragment for Example 5.3.3.
If to compare with exponential approximation of PDF with the same frequency λ, the risk to lose object safety will grow from level 0.0015 (for a year) to 0.03 (for 20 years). Difference is in 200–5000 times more against adequate PDF. The border of admissible risk 0.0015 will be reached for 195 years, not for 1.3 year as for exponential PDF. That is, the real duration of effective object operation (i.e., without losses of safety) is 150 times more! Such effect can be reached at the expense of mutual aid (reservation and supports) of skilled workers using RMS.
\nExample 5.3.4. Come back to the SUEK value chain (see Figure 10). According to system engineering principles (see ISO/IEC/IEEE 15288 and Figure 1), we decompose logically this chain into nine serial components. Components from 1 to 6 are united by MFSS of mine, component 7 is associated with washing factory, component 8 is associated with transport, component 9 is associated with port (see Figure 18). For every element of this chain, a specific set of threats exists. Let us analyze a system of such value chain. The typical systems of this value chain, including MFSS, are:
\nIllustration of system, combined from parallel and series subsystems.
The control system of ventilation and local airing equipment.
The system of modular decontamination equipment and compressed air control.
The system of air and gas control.
The system of air dust content control.
The system of dynamic phenomena control and forecasting.
The system of fire prevention protection.
The safety system of washing factory.
The safety system for transport.
The safety system of port.
What about the safety for analyzed value chain for existing threats considering possibilities of remote monitoring systems (RMS), covering all components of chain?
\nLet’s put that the workers, interacted with RMS, participate in each chain process. Their activity is modeled by the models of Section 3, considering examples above. The high adequacy is reached by decomposition of chain system to nine logical subsystems, each of which implements corresponding typical functions of Systems 1–9. Safety of whole value chain system is provided, if “AND” the first subsystem, “AND” the second, …, and “AND” the ninth subsystem safety are provided (see Figure 18). Reservation of elements for every subsystem is explained by RMS possibilities. Those input data for every element are the same as in Example 5.3.3.
\nCalculated PDF fragment shows (see Figure 19) that risk to lose safety increases from 0.000003 (for a year) to 0.0013 (for 20 years). Thus, the mean time between neighboring losses of safety Tmean equals to 283 years. That is, the frequency λ of system safety losses is about 0.0035 times a year. It is 2.3 times more often against the results of Example 5.3.3. In comparison with a primary frequency of occurrence of the latent or obvious threats (once a month), the frequency λ is 3430 times lower!
\nCalculated PDF fragment for Example 5.3.4.
For exponential approximation of PDF with the same frequency λ, the risk to lose safety will grow from level 0.0035 (for a year) to 0.07 (for 20 years). Difference is in 54–1167 times more against adequate PDF.
\nThe border of admissible risk 0.002 will be reached for 24 years, not for 7 months as for exponential PDF (see Section 2). That is, the real duration of effective operation (i.e., without losses of safety) is 41 times more!
\nExample 5.3.5. How much risks will increase, if in a system of value chain from Example 5.3.4 only medium-level workers are used?
\nCalculated PDF fragment shows (see Figure 20) that risk to lose safety increases from 0.0009 (for a year) to 0.25 (for 20 years). Thus, the mean time between neighboring losses of safety Tmean equals to 24 years. That is, the frequency λ of system safety losses is about 0.04 times a year. It is 11.4 times less often against the results of Example 4 for skilled workers. In comparison with a primary frequency of occurrence of the latent or obvious threats (once a month), the frequency λ is 21 times lower!
\nCalculated PDF fragment for Example 5.3.5.
For exponential approximation of PDF with the same frequency λ, the risk to lose safety will grow from level 0.04 (for a year) to 0.55 (for 20 years). Difference is 2.2–44.4 times more against adequate PDF. The border of admissible risk 0.002 will be reached for 2 years, not for one month as for exponential PDF. That is, the real duration of effective operation (i.e., without losses of safety) is 24 times more!
\nThe proposed probabilistic methods help the system using “smart systems”:
To predict risks to lose integrity for complex structures on the given prognostic time
To rationale of preventive measures considering admissible risk
To estimate “smart system” operation quality
To predict in real time the mean residual time before the next parameter abnormalities
The algorithm of creating more adequate PDF of time between losses of system integrity, considering for every element different threats, possibilities of control, monitoring, and recovery, allows to improve accuracy of probability predictions in hundred-thousand times (!) in comparison with exponential approximation.
\nThe purposed approach allows to improve existing risk control concept, including creation and perfection of probabilistic models for problem decision, automatic combination, and generation of new probabilistic models, forming the storehouse of risk prediction knowledge; for storehouse, dozens of variants of the decision of typical industrial problems for risk control.
\nThe application of the methods and technologies by the joint-stock company “Siberian Coal Energy Company,” implemented on the level of the remote monitoring systems, allowed to rethink system possibilities for increasing reliability and industrial safety, improve multifunctional safety systems, decrease risks, and provide predictive maintenance and operation efficiency in company value chain.
\nThe use of metals is growing up faster due to the different applications they have. Currently, different objects have been built using metals. Unfortunately, the deterioration of metallic materials is impossible to stop or avoid occurring, because the reaction of metallic materials with the present oxygen in any environment is energetically favorable and oxidation occurs spontaneously [1]. Industrially many serious and economic problems are produced for corrosion, it produces material loss on surface, and it conduce that the materials loss their mechanical properties and the structures fail making the industrial process shutting down.
In 1998 was estimated by the National Association of Corrosion Engineers (NACE) that the total annual cost generated to attend and prevent the corrosion problems in U.S.A. was closer to US $276 billion, it was approximately equivalent to the 3.1% of the Gross Domestic Product. This inversion has been growing since 2011, becoming more than US $2.2 trillion. While, in the same year was mentioned in the 1st Global Corrosion Summit that the corrosion cost in India was around US $45 billion [2]. However, these estimated data are outdated, and recently closer investigation of the NACE reported that the annual global cost of corrosion has been increased approximately to US $2.5 trillion and is equivalent to 3.4% of the global GDP [2, 3, 4]. According to a new report data, it was mentioned on 2019, it is expected that the global corrosion inhibition market will reach USD $ 9.6 Billion by 2026 [5].
The metals importance in society through the years has raised the search for efficient alternatives to protect them. Corrosion inhibitors are one of the most used methods, as they act by decreasing the corrosion velocity and the metallic surface is protected [6]. Synthetic corrosion inhibitors is the most used in industry [6, 7, 8]. However, the excessive use of inorganic and organic synthetic corrosion inhibitors during years have been produced pollution and environmental damage [9].
Different hazards occur naturally and deliberately (such as industrial pollution, transportation accidents and damage, radioactive pollution, water pollution, petroleum pollution, etc.). The hazards of most synthetic organic compounds are commonly known, and the restrictive environmental regulations of many countries forced researchers to focus on developing cheap, nontoxic, and environmentally acceptable products [10, 11].
The metallic protection or the use of corrosion inhibitors cause significatively pollution. Therefore, environmental protection legislation raised to prevent using the environmentally unacceptable materials such as the use of chromium salts is now restricted because chromium (Cr+6) is highly toxic and carcinogenic [12, 13]. Every year, billions of dollars are spent on capital replacement and methods for corrosion control in infrastructure [14, 15].
Since the nineties researchers have been searched and studied new and different alternatives for metal protection because the corrosion has drawn considerable academic and industrial attention [10, 16, 17]. Various researchers keeping these ideas in mind have been focused on studying the corrosion inhibitors activity of expired nontoxic medicines, natural molecules that come from microorganisms [18], and others have been oriented to study plant extracts which contain many natural and eco-friendly organic compounds [19]. An appropriate green corrosion control can help to avoid many potential disasters that can cause serious issues including life-loss, negative social impacts, water resource and environmental pollution. In this way green corrosion inhibition studies have become oriented towards human health and safety considerations [14, 20]. However, different studies have shown that green corrosion inhibition effect is usually found to be very low compared to synthetic organic inhibitors [10].
Likewise, it has been suggested to focus the studies in plant extracts or single natural products as corrosion inhibitors until reaching their application. Accordingly, there is an increasing demand to protect the environment by decreasing and controlling all causes, which pollute the environment, damage society’s health, and affect the economy [21].
Metal corrosion is an unavoidable chemical process; it is defined as the deterioration of desired metal properties on interaction with certain elements that are present in the environment. Material’s degradation is associated with the term erosion which means
Chemically, corrosion is an oxide-reduction reaction; it commonly occurs an interchange or transferred the valency electrons between metal and the major element present in their environment, e.g., oxygen in air or water [23]. In the industrial practices certain processes like acidizing, acid cleaning, pickling, etc. facilitate metal corrosion, because the metal surface reacts quickly with pH solution, temperature, ions, etc. However, corrosion rate depends on the cell or environmental conditions. In the Figure 1 is represented the electrochemical process that is carried on in the oxide-reduction reaction of steel (Figure 1) under aqueous system.
Metallic corrosion (cell and metal surface).
The corrosion occurs, in an aqueous or wet environment, when the metal is in contact with an electrolytic conducting liquid or when two dissimilar metals or alloys are either immersed or dipped partially in the electrolytic conducting solutions [20].
Where
In acid solution
In alkaline solution
In neutral solution
These reactions are always associated with standard conditions to explaining the phenomenon of metal corrosion degradation (Figure 1).
Metal corrosion rate could be reduced or mitigated through different strategies such are to cover the metal surface with painting or coatings; with the respective oxide that is formed through passivation or by reducing the aggressivity of the medium [24]. Those are to protect the metal and to reduce the damage.
Various authors reported the successful corrosion inhibition activity (CIA) exhibited by organic compounds, it depends on the presence of functional groups in their chemical structure, those containing elements such as
General representation of organic chemical structures included heteroatoms.
On the other hand, other reports mentioned that aromatic rings contain double bonds and π electrons, those are important as they do favorable chelator interactions on the metal surface too [25, 26]. Compounds which frequently depends on the presence of functional groups in their chemical structure and electron pairs provided by heteroatoms such as N, O, P or S; these features and the presence of pi electrons as double or triple carbon–carbon bonds enable this compounds to form favorable interactions with the metal surface (Figure 2).
Some interesting aspect is that the nature provides different natural organic compounds, in which those chemical characteristics are present. Additionally, several of these compounds have antioxidant activity which has been related with anticorrosion activity or corrosion inhibition [27]. The interference with the flow of electrons reduces the reaction rate and gives protection to the metal.
All previous aspects motivate to perform the study of corrosion inhibition activity and to observe how the corrosion rate is reduced and how the inhibitor act and how much time gives protection to the metal surface [26, 27, 28]. In Table 1 it is shown some examples of green corrosion inhibitors for some species. Green corrosion inhibitors have been positioned as a good alternative because they have come from natural sources, so they are considered less toxic, biodegradables, ecofriendly, and sustainable [1, 10, 26, 38, 39].
Traditionally the plants are used in infusion or tee, it could be the reason why in many studies have been performed water infusion as green corrosion inhibitors, however the corrosion inhibition efficiencies reported show low percentage of inhibition, one of the strategies observed in the reports is using more quantity of phytoextract to increase the corrosion inhibition efficiencies [30]. In another hand, the wide way to employ plants is in cosmetic, many works reported the study of essential oils as green corrosion inhibitor [32]. Other studies reported acid or basic extraction, it is depending on the electrolyte used, for example if the study is made in hydrochloric acid the extraction of inhibitor is made in HCl and heat [31]. These kinds of extractions are stronger and exhausted, it destroys not only the tissue, frequently modified chemically the compounds.
Organic and natural compounds are chemically sensible and thermolabile and through their functional groups reacts with acid or bases, for example the functional group alcohol in acid environment is going to transform into carboxylic acid, and tannins are going to separate into their monomeric units; other groups such as ring with oxygen as heteroatom like lactones tend to open the ring and the compounds interchange in a different position to the original. In the same way the thermolabile compounds with the heat suffer inactivation and chemical destruction [40]. The phytochemicals extraction method is an important step to recover the green corrosion inhibitor because extraction separates the desired natural products from the raw materials and follows to continue the study of chemical structure of the molecule responsible of the inhibition activity. The properties of the extraction solvent, the particle size of the raw materials, the solvent-to-solid ratio, the extraction temperature, and the extraction duration will affect the extraction efficiency [41].
The plants are considered and the diversity of phytochemical compounds could be different for the same species of plant that grew in different locations and in different tissue of the same plant biosynthesize can present different kind of natural compounds, and the kind of phytochemical biosynthesize depend on the age or stage, because it is not the same old barks than mature leaves or flowers than suckers [42]. In this way different tissue of plants have been processed, extracted, studied and reported as green corrosion inhibitors employing different alloys and electrolytes. In the Table 2 are shown examples of specified tissue plant extracted and studied as green corrosion inhibitors.
Rosaceae is a moderately large angiosperm family in Rosales order, with about 3000 species, 3 subfamilies, 16 tribes, and 88–100 genera [55, 56, 57]. Rosaceae is a family plant producing seeds within the fruits. The fruit protects the seeds against damage from pathogens, water loss, and the other stresses. Rosaceae family have an important commercial fruit species, fruits are highly nutritious and are consumed by humans, they have benefited greatly by freshy or drier fruits including woodland strawberry (
Different documents mentioned that peach was originated in China and then spread westward through Asia to the Mediterranean countries and later to other parts of Europe. The Spanish explorers took the peach to the New World, and in the early 1600 the fruit was found in Mexico. The large-scale commercial peach growing did not begin until the 19th century, in the United States. The early plantings were seedling peaches, inevitably variable, and often of poor quality. The practice of grafting superior strains onto hardy seedling rootstocks, which came later in the century, led to the development of large commercial orchards [61, 62, 63, 64, 65].
Peach trees are relatively short-lived as compared with some other fruit trees. In some regions orchards are replanted after 8 to 10 years, while in others trees may produce satisfactorily for 20 to 25 years or more. Trees are usually pruned annually to prevent them from becoming too tall; the upright shoots are pruned back to outgrowing laterals to produce a spreading tree and keep it open to sunlight. Small to medium-sized peach trees seldom reach 6.5 meters (21 feet) in height. Under cultivation, however, they are usually kept between 3 and 4 meters (10 and 13 feet) by pruning. The leaves are glossy green, lance-shaped, and long pointed; they usually have glands at their bases that secrete a fluid to attract ants and other insects. The flowers, borne in the leaf axils, are arranged singly or in groups of two or three at nodes along the shoots of the previous season’s growth. The five petals, usually pink but occasionally white, five sepals, and three whorls of stamens are borne on the outer rim of the short tube, known as the hypanthium, that forms the base of the flower (Figure 3) [61, 62].
Peach tree without and with fruit and flowers.
Thousands of varieties of peach have been developed. Varieties may be freestone types, which have stones that separate easily from the ripe flesh, or clingstones, which have flesh that adheres firmly to the stone. The skin of most ripe peaches is downy or fuzzy; peaches with smooth skins are called nectarines (Figure 4) [65]. Worldwide, the peach is one of the most important of the deciduous-tree fruits, and China, Italy, Spain, and the United States are major producers.
Peach fruits commercially available. Common name in black color, scientific name in blue color, synonym un green color.
Peaches and apricots belong to the same family,
However, peaches provide higher amounts of these nutrients in a single serving because of their larger size.
Different efforts have been oriented in the search and study of species that could be applied as green corrosion inhibitors. And the peach does not an exception because has antioxidant activity and the compounds have been reported as responsible from this activity are polyphenols and carotenoids [63, 64, 66]. Likewise, the peaches are widely produced around the world because they are good and harmless for the health [66], and many products are derived from their industrializing, and it generates high quantities of agro-waste, which can be used to produce green corrosion inhibitors [67, 68]. In this way, we are interested to aim and analyze the different results reported over the activity of
The scientific reports on
Source of green corrosion inhibitor Natural specie Type pf extract Natural products reported | Experimental conditions Metal or alloy & Electrolyte & [Green corrosion inh conc] | Inhibitive performance | Ref |
---|---|---|---|
Cosmetic oil Oleic acid (fatty acids) and Schottenol (terpene) | Mild steel 1.0 M HCl 3.0 gL | CIE = 81.0% By weight lost in 8 h as residence time | [29] |
Methanol and Water N. M. | Aluminum 1.0 M H2SO4 4.0 gL | CIEM = 65.78% CIEW = 50.88% By weight lost in 3 h as residence time | [30] |
Acid aqueous extract N. M. | Carbon steel 1.0 M HCl 2.0 gL | CIE = 91.1% By weight lost | [31] |
Essential oil Carvacrol | C38 steel 0.5 M H2SO4 2.0 gL | CIE = 72.2% By weight lost in 6 h as residence time | [32] |
Powder extracted using water Caryophyllene, Germacrene, Chlorogenic acid, Luteonin, Rosmarinic acid, and Citral | Mild steel 1.0 M HCl 0.8 gL | CIE = 95.0% By weight lost in 12 h as residence time | [33] |
Powder extracted using ethanol Gallic acid, Iriflophenone, and Mangiferin | Mild steel 1.0 M HCl 1.0 gL | CIE = 92.0% By weight lost in 8 h as residence time | [34] |
Essential oil Camphor | Steel 0.5 M H2SO4 2.0 gL | CIE = 86.12% By weight lost in 6 h as residence time | [35] |
Methanol extract Flavonoids: Silybin, Silychristin, Isosilybin and Silydanin | 304 stainless steel 1.0 M HCl 0.6 gL | CIE = 89.7% By weight lost in 6 h as residence time | [36] |
Methanol N. M. | Mild steel 1.0 M HCl 0.5 gL | CIE = 88.0% By weight lost in 3 h as residence time | [37] |
Studies of green corrosion inhibitor reported.
CIE, Corrosion inhibition efficiency; CIEM, Corrosion inhibition efficiency of methanol extract; CIEW, Corrosion inhibition efficiency of water extract; N. M., Non mentioned.
Source of green corrosion inhibitor Specie Tissue Solvent employed by maceration extraction Natural product reported | Experimental conditions Metal or alloy Electrolyte Inh conc [g/L] | Inhibitive performance weight lost technique | Ref |
---|---|---|---|
Bulbs Hexane Allicin | Carbon steel 0.5 M H2SO4 0.4 gL | CIEH = 96.0% | [43] |
Flowers Hexane, ketone, methanol individual maceration Hyoscyamine; Anisodamine, and Scopolamine | 1018 steel 0.5 M H2SO4 0.4 gL | CIEH = 90.0% CIEk = 80.0% CIEM = 78.0% | [44] |
Stems and leaves Hexane N. M. | 1018 steel 0.5 M H2SO4 0.25 gL | CIEH = 80.0% | [45] |
Turmeric Hexane, methanol individual maceration Mainly Curcuminoids | 1018 mild steel 3.5% NaCl 0.1 gL | CIEH = 62.6% CIEM = 93.7% | [46] |
Fruit Methanol 2,3-dihydro-3,5-dihydroxy-6-methyl(R)-4H-piran-4-on; Quinic acid; Octadecanoic acid; 9,12-Octadecadienoic acid; 9,12-Octadecadienoic acid, methyl ester; Hexadecenoic acid and Hexadecenoic acid, methyl ester; Stigmasterol, and β-Sitosterol | 1018 steel 0.5 M H2SO4 1.0 gL | CIEM = 89.0% | [47] |
Leaves Methanol Hexadecenoic acid; 9,12-octadecadienoic acid; oleanolic acid, methyl ester; Campesterol, and β-Sitosterol | A36 steel 0.5 M H2SO4 0.4 gL | CIEM = 78.0% | [48] |
Stems and leaves Methanol Hexadecenoic acid; 9,12-octadecadienoic; oleanolic acid; Cymene, and Limonene | 1018 steel 0.5 M H2SO4 0.5 gL | CIEM = 92.0% | [49] |
Stems and leaves Methanol Oleic acid; Stearic acid, Limonene, Cymene, and 5-hydroxymethylfurfural | 1018 steel 0.5 M H2SO4 0.6 gL | CIEM = 88.0% | [50] |
Leaves Methanol Chrysin; Boldine, and α-Tocopherol | Carbon steel 0.5 M H2SO4 1.0 gL | CIEM = 73.0% | [51] |
Branches Methanol Prosopine and Prosopinine | Aluminum 0.5 M H2SO4 0.2 gL | CIEM = 40.5% | [52] |
Stems and leaves Hexane, ketone, methanol individual maceration Carnosol, Carnosic acid, and Rosmarinic acid | Carbon steel 0.5 M H2SO4 1.0 gL | CIEH = 62.5% CIEk = 50.0% CIEM = 42.6% | [53] |
Stems and leaves Methanol Carnosol, Limonene, and Rosmarinic acid | Carbon steel 0.5 M H2SO4 0.3 gL | CIEM = 80.0% | [54] |
Tissue of plants to obtain green corrosion inhibitors.
N. M., Non mentioned in the paper; CIEH, Corrosion inhibition efficiency of hexane extract; CIEk, Corrosion inhibition efficiency of ketone extract CIEM, Corrosion inhibition efficiency of methanol extract.
Specie (common name) | Experimental conditions Alloy Electrolyte Inh conc [g/L] | Inhibitive performance | Ref |
---|---|---|---|
Tissue Extracted technique Natural product reported | |||
Fruits Soxhlet extraction using 2-propanol/ethanol Octadecanoic acid; (9Z)-octadec-9-enoic acid; Linalool; α-terpineol; geraniol; nerolidol | Mild steel St7–2 0.5 M Na2SO4, pH 7.2 100 gL | CIE by WL 97.6% in 21 days as residence time CIE by PPC 89.0% in 72 h as residence time | [69] |
Fruits Soxhlet extraction using 95% Ethanol N. M. | Mild steel 0.5 M NaCl 0.5 gL | CIE by WL 94.6% in 26 days as residence time | [70] |
Fruits Mechanical juice N. M. | Mild steel 1.0 M H3PO4 40.0 gL | CIE by WL 75.0% in 2 h as residence time | [71] |
Seeds Essential oil Oleic acid; Linoleic acid; Palmitic acid; Stearic acid | C38 Carbon steel 1.0 M HCl 0.5 gL | CIE by WL 84.0% in 6 h as residence time CIE by PPC 84.0% CIE by EIS 83.5% | [72] |
Gum N. M. N. M. | Carbon steel 0.5 M H3PO4 0.5 gL | CIE by PPC 86.0% CIE by EIS 81.0% | [73] |
Pomace Soxhlet extraction using 2-propanol β-cyclocitral; оctadecanoic acid; hexadecanoic acid; (9Z)-octadec-9-enoic acid; Terpineol; Geraniol; Nerolidol | Mild steel 0.5 M NaCl 0.5 gL | CIE by WL 94.6% in 26 days as residence time | [74] |
Leaves Reflux distillation with water Phenolic compounds and anthocyanins | Mild steel 0.5 M HCl 0.40 gL | CIE by PPC 61.0% CIE by EIS 55.0% | [75] |
Fruits Mechanical compressed to obtained juice N.M. | St-37 Steel 1.0 M HCl ∼40* gL | CIE by PPC 94.1% CIE by EIS 92.7% | [76] |
Fruit peels Methanol and water Catechin, Chlorogenic acid, and Isorhamnetin-3-o-rutinoside | Mild steel 0.1 M HCl 0.12 gL 0.24 gL | CIE by WL 93.0 and 85%, respectively CIE by PPC 09 & 83.0%, respectively CIE by EIS 92.0 and 88.0%, respectively | [77] |
Seeds Soxhlet extraction using hexane Phenolic compounds, Saponins, Tannins, Flavonoids, and proanthocyanidins | Mild steel 1.5 M HCl 150 gL | CIE by WL 68.0% in 20 h as residence time | [78] |
Leaves Methanol maceration Kaempferol, Quercetin, Rutin, Ursolic acid, Daucosterol, and | 1018 Carbon steel 0.5 M H2SO4 0.60 gL | CIE by WL 80.0% CIE by PPC 92.0% CIE by EIS 97.0% | [79] |
Pomace Ultrasound dissolved in 2-propanol/ethanol/water Cinnamaldehyde, Thymol, Decosanal, a-Terpineol, and Linalool | Carbon steel 0.5 M NaCl 0.8 gL | CIE by WL 80.0% in 45 h as residence time | [80] |
Fruits Mechanical compressed to obtained Juice N.M. | Mild steel 1.0 M HCl 0.05 gL | CIE by WL 88.0% at 50°C CIE by PPC 90.0% | [81] |
Species of Prunus studied as green corrosion inhibitors.
N. M., Non mentioned in the paper; CIEH, Corrosion inhibition efficiency of hexane extract; CIEk, Corrosion inhibition efficiency of ketone extract CIEM, Corrosion inhibition efficiency of methanol extract.
Different tissues of peach have been used and extracted by different ways to recover natural and organic compounds to study as green corrosion inhibitors. The fruits, seeds, pomace, and gum of
The leaves of
The fruit peels and seeds of
The leaves, fruits, and pomace of
The phytoextracts from
The best natural material of peach to obtain and for particular interest as green corrosion inhibitor could be the leaves, because these are not commercial than fruits, and in orchards many threes are pruned, and the leaves are disposable as residues. Other kind of residues from peaches are produced by the food industry or jam and juice factories, they discarded and waste dispose peels, seeds, and pomace of peaches (Figure 5).
Obtaining and studying the green corrosion inhibitor of
Recently was reported the use and approval of peaches waste to produce green corrosion inhibitors with prolongated activity on mild steel [82]. Different compounds are chemically detected and reported from
Natural compounds reported for
The inhibition performance of loquat (
β-Sitosterol (
In another hand, the potential of flavonoid extract of
The
According to the literature flavonoids were found in the infusions of
Folin–Ciocalteu reagent was used to assess total phenolic content present in apricot samples and were compared with the blue complex formed of gallic acid using as a standard. Aluminum chloride method was used for the detection of total flavonoid content producing a yellow color due to the presence of flavonoids; in this case Quercetin was used as a standard for the measurement of flavonoids. The results shown that fruits of
Phytochemicals frequently are considered “organic, natural and safe compounds”. However is adequate, proper, and scientifically correct to determine that green corrosion inhibitors are not toxic substances at the concentration are active as corrosion inhibitors, and at the same time to confirm they are safe to the human and environment. Are few reports of green corrosion inhibitors with good corrosion inhibition efficiencies that included the determination of toxicity.
However, for
The phytoextracts extracted from
The high content of flavonoids was found in leaves and pomace of
The authors declare no conflict of interest.
M | Molar |
H2SO4 | Sulfuric acid |
HCl | Chloride acid |
gL−1 | grams per liter |
ppm | parts per million |
N. M. | Non mentioned in the paper |
CIEH | Corrosion inhibition efficiency of hexane extract |
CIEk | Corrosion inhibition efficiency of ketone extract |
CIEM | Corrosion inhibition efficiency of methanol extract. |
WL | weight lose |
PPC | Potentiodynamic polarization curves |
EIS | Electrochemical Impedance Spectroscopy |
HPLC | High performance liquid chromatograph |
LC50 | Lethal concentration, 50% |
This is a brief overview of the main steps involved in publishing with IntechOpen Compacts, Monographs and Edited Books. Once you submit your proposal you will be appointed a Author Service Manager who will be your single point of contact and lead you through all the described steps below.
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Foodborne diseases can be prevented and acute diarrhea syndromes, fever and even death from dehydration can be avoided, especially in children under the age of 5 and in immunocompromised people.",book:{id:"5873",slug:"poisoning-from-specific-toxic-agents-to-novel-rapid-and-simplified-techniques-for-analysis",title:"Poisoning",fullTitle:"Poisoning - From Specific Toxic Agents to Novel Rapid and Simplified Techniques for Analysis"},signatures:"Cecilia Hernández-Cortez, Ingrid Palma-Martínez, Luis Uriel\nGonzalez-Avila, Andrea Guerrero-Mandujano, Raúl Colmenero Solís\nand Graciela Castro-Escarpulli",authors:[{id:"204160",title:"Prof.",name:"Graciela",middleName:null,surname:"Castro-Escarpulli",slug:"graciela-castro-escarpulli",fullName:"Graciela Castro-Escarpulli"},{id:"204162",title:"Dr.",name:"Cecilia",middleName:null,surname:"Hernández-Cortez",slug:"cecilia-hernandez-cortez",fullName:"Cecilia Hernández-Cortez"},{id:"204163",title:"MSc.",name:"Ingrid",middleName:null,surname:"Palma-Martinez",slug:"ingrid-palma-martinez",fullName:"Ingrid Palma-Martinez"},{id:"204164",title:"MSc.",name:"Luis Uriel",middleName:null,surname:"González-Avila",slug:"luis-uriel-gonzalez-avila",fullName:"Luis Uriel González-Avila"},{id:"204165",title:"MSc.",name:"Andrea",middleName:null,surname:"Guerrero-Mandujano",slug:"andrea-guerrero-mandujano",fullName:"Andrea Guerrero-Mandujano"}]},{id:"56530",doi:"10.5772/intechopen.69955",title:"Poisoning by Anticoagulant Rodenticides in Humans and Animals: Causes and Consequences",slug:"poisoning-by-anticoagulant-rodenticides-in-humans-and-animals-causes-and-consequences",totalDownloads:1847,totalCrossrefCites:10,totalDimensionsCites:17,abstract:"Anticoagulant rodenticides (ARs) are a keystone of the management of rodent populations in the world. The widespread use of these molecules raises questions on exposure and intoxication risks, which define the safety of these products. Exposures and intoxications can affect humans, domestic animals and wildlife. Consequences are different for each group, from the simple issue of intoxication in humans to public health concern if farm animals are exposed. After a rapid presentation of the mechanism of action and the use of anticoagulant rodenticides, this chapter assesses the prominence of poisoning by anticoagulant rodenticides in humans, domestic animals and wildlife.",book:{id:"5873",slug:"poisoning-from-specific-toxic-agents-to-novel-rapid-and-simplified-techniques-for-analysis",title:"Poisoning",fullTitle:"Poisoning - From Specific Toxic Agents to Novel Rapid and Simplified Techniques for Analysis"},signatures:"Sébastien Lefebvre, Isabelle Fourel, Stéphane Queffélec, Dominique\nVodovar, Bruno Mégarbane, Etienne Benoit, Virginie Siguret and\nVirginie Lattard",authors:[{id:"180156",title:"Dr.",name:"Virginie",middleName:null,surname:"Lattard",slug:"virginie-lattard",fullName:"Virginie Lattard"},{id:"185579",title:"Dr.",name:"Sébastien",middleName:null,surname:"Lefebvre",slug:"sebastien-lefebvre",fullName:"Sébastien Lefebvre"},{id:"185580",title:"Prof.",name:"Etienne",middleName:null,surname:"Benoit",slug:"etienne-benoit",fullName:"Etienne Benoit"},{id:"209023",title:"Dr.",name:"Isabelle",middleName:null,surname:"Fourel",slug:"isabelle-fourel",fullName:"Isabelle Fourel"},{id:"209031",title:"Mr.",name:"Stéphane",middleName:null,surname:"Queffélec",slug:"stephane-queffelec",fullName:"Stéphane Queffélec"},{id:"209032",title:"Dr.",name:"Bruno",middleName:null,surname:"Megarbane",slug:"bruno-megarbane",fullName:"Bruno Megarbane"},{id:"209033",title:"Dr.",name:"Dominique",middleName:null,surname:"Vodovar",slug:"dominique-vodovar",fullName:"Dominique Vodovar"},{id:"209034",title:"Prof.",name:"Virginie",middleName:null,surname:"Siguret",slug:"virginie-siguret",fullName:"Virginie Siguret"}]},{id:"51450",doi:"10.5772/63888",title:"ECMO Biocompatibility: Surface Coatings, Anticoagulation, and Coagulation Monitoring",slug:"ecmo-biocompatibility-surface-coatings-anticoagulation-and-coagulation-monitoring",totalDownloads:4442,totalCrossrefCites:10,totalDimensionsCites:17,abstract:"The interaction between the patient and the ECMO (extracorporeal membrane oxygenation) circuit initiates a significant coagulation and inflammatory response due to the large surface area of foreign material contained within the circuit. This response can be blunted with the appropriate mix of biocompatible materials and anticoagulation therapy. The use of anticoagulants, in turn, requires appropriate laboratory testing to determine whether the patient is appropriately anticoagulated. Physicians must balance the risks of bleeding with the risks of thrombosis; the proper interpretation of these tests is often shrouded in mystery. It is the purpose of this chapter to help demystify the coagulation system, anticoagulants, biocompatible surfaces, and coagulation testing so that ECMO practitioners can make informed decisions about their patients and to spur coordinated efforts for future research to improve our understanding of these complex processes.",book:{id:"5202",slug:"extracorporeal-membrane-oxygenation-advances-in-therapy",title:"Extracorporeal Membrane Oxygenation",fullTitle:"Extracorporeal Membrane Oxygenation - Advances in Therapy"},signatures:"Timothy M. Maul, M Patricia Massicotte and Peter D. Wearden",authors:[{id:"182691",title:"Dr.",name:"Timothy",middleName:"Michael",surname:"Maul",slug:"timothy-maul",fullName:"Timothy Maul"},{id:"187110",title:"Dr.",name:"Peter",middleName:null,surname:"Wearden",slug:"peter-wearden",fullName:"Peter Wearden"},{id:"187112",title:"Dr.",name:"Patti",middleName:null,surname:"Massicotte",slug:"patti-massicotte",fullName:"Patti Massicotte"}]},{id:"39638",doi:"10.5772/51484",title:"The History of Sepsis from Ancient Egypt to the XIX Century",slug:"the-history-of-sepsis-from-ancient-egypt-to-the-xix-century",totalDownloads:10553,totalCrossrefCites:5,totalDimensionsCites:15,abstract:null,book:{id:"2583",slug:"sepsis-an-ongoing-and-significant-challenge",title:"Sepsis",fullTitle:"Sepsis - An Ongoing and Significant Challenge"},signatures:"Johan Sebastián Hernández Botero and María Cristina Florián Pérez",authors:[{id:"141171",title:"Dr.",name:"Johan",middleName:"Sebastian",surname:"Hernandez Botero",slug:"johan-hernandez-botero",fullName:"Johan Hernandez Botero"},{id:"141520",title:"Dr.",name:"Maria Cristina",middleName:null,surname:"Florian Perez",slug:"maria-cristina-florian-perez",fullName:"Maria Cristina Florian Perez"}]}],mostDownloadedChaptersLast30Days:[{id:"56521",title:"Food Poisoning Caused by Bacteria (Food Toxins)",slug:"food-poisoning-caused-by-bacteria-food-toxins-",totalDownloads:5880,totalCrossrefCites:9,totalDimensionsCites:20,abstract:"In the environment, there are polluting substances that can cause adverse reactions in human beings when entering the body through different ways (ingestion, inhalation, injection, or absorption). The main pollutants can be poisons, chemical compounds, toxic gases, and bacterial toxins. These can be found in different places and their effects depend on the dose and exposure time. Furthermore, foodborne diseases (FBDs) can cause disability; these diseases can be caused by toxins produced by bacteria or other toxic substances in the food, which can cause severe diarrhea, toxic shock syndrome, debilitating infections such as meningitis and even death. FBDs are transmitted through food contaminated with pathogenic microorganisms that have multiple factors of virulence, which gives them the ability to cause an infection; some bacterial genres can produce toxins directly in the food, but other genres can produce them once they have colonized the intestine. Among the pathogens involved in FBDs that are also considered to be toxigenic are Salmonella spp., Vibrio parahaemolyticus, Vibrio cholerae, Staphylococcus aureus, Clostridium botulinum, Clostridium perfringens, Bacillus cereus, Listeria monocytogenes. Foodborne diseases can be prevented and acute diarrhea syndromes, fever and even death from dehydration can be avoided, especially in children under the age of 5 and in immunocompromised people.",book:{id:"5873",slug:"poisoning-from-specific-toxic-agents-to-novel-rapid-and-simplified-techniques-for-analysis",title:"Poisoning",fullTitle:"Poisoning - From Specific Toxic Agents to Novel Rapid and Simplified Techniques for Analysis"},signatures:"Cecilia Hernández-Cortez, Ingrid Palma-Martínez, Luis Uriel\nGonzalez-Avila, Andrea Guerrero-Mandujano, Raúl Colmenero Solís\nand Graciela Castro-Escarpulli",authors:[{id:"204160",title:"Prof.",name:"Graciela",middleName:null,surname:"Castro-Escarpulli",slug:"graciela-castro-escarpulli",fullName:"Graciela Castro-Escarpulli"},{id:"204162",title:"Dr.",name:"Cecilia",middleName:null,surname:"Hernández-Cortez",slug:"cecilia-hernandez-cortez",fullName:"Cecilia Hernández-Cortez"},{id:"204163",title:"MSc.",name:"Ingrid",middleName:null,surname:"Palma-Martinez",slug:"ingrid-palma-martinez",fullName:"Ingrid Palma-Martinez"},{id:"204164",title:"MSc.",name:"Luis Uriel",middleName:null,surname:"González-Avila",slug:"luis-uriel-gonzalez-avila",fullName:"Luis Uriel González-Avila"},{id:"204165",title:"MSc.",name:"Andrea",middleName:null,surname:"Guerrero-Mandujano",slug:"andrea-guerrero-mandujano",fullName:"Andrea Guerrero-Mandujano"}]},{id:"64561",title:"Musculoskeletal Injuries: Types and Management Protocols for Emergency Care",slug:"musculoskeletal-injuries-types-and-management-protocols-for-emergency-care",totalDownloads:2489,totalCrossrefCites:1,totalDimensionsCites:3,abstract:"These are a common type of human injuries which can result from the damage of muscular or skeletal systems (i.e., bones, muscles, tendons, ligaments, nerves, blood vessels, etc.); they usually occur due to a strenuous and/or repetitive activity and can result into variety of complaints, complications, and deformities causing a big burden on the financial and health system in all societies. They are among the largest category of work-related injuries and are responsible for almost 30% of all worker’s compensation costs worldwide. Injuries to the musculoskeletal system occur in 85% of patients who sustain blunt trauma; they often appear dramatic, but rarely cause an immediate life-threatening situation, although these injuries must be assessed and managed accurately so life or limb are not jeopardized. The doctor must be familiar with the anatomy and the injury site to protect his patients from further disability and prevent complications. Major musculoskeletal trauma such as crushed injuries that can cause release of myoglobin resulting in renal tubular injury (acute kidney injury), or can be associated with internal torso injuries like acute compartment syndrome. soft tissue and skeletal system traumas may not be initially recognized, so continued reassessment and evaluation are necessary to identify all injuries.",book:{id:"6616",slug:"essentials-of-accident-and-emergency-medicine",title:"Essentials of Accident and Emergency Medicine",fullTitle:"Essentials of Accident and Emergency Medicine"},signatures:"Ahmad Subhy Alsheikhly and Mazin Subhy Alsheikhly",authors:[{id:"144628",title:"Prof.",name:"Ahmad Subhy",middleName:"Humadi",surname:"Alsheikhly",slug:"ahmad-subhy-alsheikhly",fullName:"Ahmad Subhy Alsheikhly"}]},{id:"59641",title:"Problem of Burns in Children: Opportunities for Health Improvement",slug:"problem-of-burns-in-children-opportunities-for-health-improvement",totalDownloads:1415,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"Burns are one of the most devastating types of trauma in medicine. Children under 5 years of age are a high-risk group to burns. The most common type is thermal burn caused by hot fluids (scald). Most childhood burns occur at home under parental supervision. These are preventable injuries. The chapter presents results of my studies about risk factors of burns in children and possibilities of health improvement. Simple changes in children’s environment and increasing awareness of caregivers can lead to a decrease in the number of this type of injuries. Moreover, the first aid given to burnt children soon after the injury usually is not adequate (no cooling thermal burns and no analgesia). Health improvement can be obtained by reducing the number of burns, the correct first aid given after the injury, and the organization of specialized health-care centers and rehabilitation services for victims of burns.",book:{id:"6616",slug:"essentials-of-accident-and-emergency-medicine",title:"Essentials of Accident and Emergency Medicine",fullTitle:"Essentials of Accident and Emergency Medicine"},signatures:"Agata Maria Kawalec",authors:null},{id:"51795",title:"ECMO Cannulation Techniques",slug:"ecmo-cannulation-techniques",totalDownloads:4333,totalCrossrefCites:2,totalDimensionsCites:3,abstract:"An extracorporeal membrane oxygenation (ECMO) circuit consists of a pump and a membrane oxygenator. This circuit can interface with the human body in a variety of cannulation strategies to provide different forms and levels of support. These various support techniques can be divided into two broad categories: those designed to support the body’s respiratory functions (lungs) and those designed to support the body’s blood circulation (heart). In this chapter we discuss various cannulation techniques used.",book:{id:"5202",slug:"extracorporeal-membrane-oxygenation-advances-in-therapy",title:"Extracorporeal Membrane Oxygenation",fullTitle:"Extracorporeal Membrane Oxygenation - Advances in Therapy"},signatures:"Chand Ramaiah and Ashok Babu",authors:[{id:"183646",title:"Dr.",name:"Chand",middleName:null,surname:"Ramaiah",slug:"chand-ramaiah",fullName:"Chand Ramaiah"},{id:"189073",title:"Dr.",name:"Ashok",middleName:null,surname:"Babu",slug:"ashok-babu",fullName:"Ashok Babu"}]},{id:"27955",title:"Transfusion-Associated Bacterial Sepsis",slug:"transfusion-associated-sepsis",totalDownloads:8276,totalCrossrefCites:1,totalDimensionsCites:2,abstract:null,book:{id:"802",slug:"severe-sepsis-and-septic-shock-understanding-a-serious-killer",title:"Severe Sepsis and Septic Shock",fullTitle:"Severe Sepsis and Septic Shock - Understanding a Serious Killer"},signatures:"Jolanta Korsak",authors:[{id:"72828",title:"Prof.",name:"Jolanta",middleName:null,surname:"Korsak",slug:"jolanta-korsak",fullName:"Jolanta Korsak"}]}],onlineFirstChaptersFilter:{topicId:"177",limit:6,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:90,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:104,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:32,numberOfPublishedChapters:320,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:12,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:141,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:133,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:113,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:107,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:5,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:16,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}},{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}}]},series:{item:{id:"14",title:"Artificial Intelligence",doi:"10.5772/intechopen.79920",issn:"2633-1403",scope:"Artificial Intelligence (AI) is a rapidly developing multidisciplinary research area that aims to solve increasingly complex problems. In today's highly integrated world, AI promises to become a robust and powerful means for obtaining solutions to previously unsolvable problems. This Series is intended for researchers and students alike interested in this fascinating field and its many applications.",coverUrl:"https://cdn.intechopen.com/series/covers/14.jpg",latestPublicationDate:"July 5th, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:9,editor:{id:"218714",title:"Prof.",name:"Andries",middleName:null,surname:"Engelbrecht",slug:"andries-engelbrecht",fullName:"Andries Engelbrecht",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRNR8QAO/Profile_Picture_1622640468300",biography:"Andries Engelbrecht received the Masters and PhD degrees in Computer Science from the University of Stellenbosch, South Africa, in 1994 and 1999 respectively. He is currently appointed as the Voigt Chair in Data Science in the Department of Industrial Engineering, with a joint appointment as Professor in the Computer Science Division, Stellenbosch University. Prior to his appointment at Stellenbosch University, he has been at the University of Pretoria, Department of Computer Science (1998-2018), where he was appointed as South Africa Research Chair in Artifical Intelligence (2007-2018), the head of the Department of Computer Science (2008-2017), and Director of the Institute for Big Data and Data Science (2017-2018). In addition to a number of research articles, he has written two books, Computational Intelligence: An Introduction and Fundamentals of Computational Swarm Intelligence.",institutionString:null,institution:{name:"Stellenbosch University",institutionURL:null,country:{name:"South Africa"}}},editorTwo:null,editorThree:null},subseries:{paginationCount:6,paginationItems:[{id:"22",title:"Applied Intelligence",coverUrl:"https://cdn.intechopen.com/series_topics/covers/22.jpg",isOpenForSubmission:!0,annualVolume:11418,editor:{id:"27170",title:"Prof.",name:"Carlos",middleName:"M.",surname:"Travieso-Gonzalez",slug:"carlos-travieso-gonzalez",fullName:"Carlos Travieso-Gonzalez",profilePictureURL:"https://mts.intechopen.com/storage/users/27170/images/system/27170.jpeg",biography:"Carlos M. Travieso-González received his MSc degree in Telecommunication Engineering at Polytechnic University of Catalonia (UPC), Spain in 1997, and his Ph.D. degree in 2002 at the University of Las Palmas de Gran Canaria (ULPGC-Spain). He is a full professor of signal processing and pattern recognition and is head of the Signals and Communications Department at ULPGC, teaching from 2001 on subjects on signal processing and learning theory. His research lines are biometrics, biomedical signals and images, data mining, classification system, signal and image processing, machine learning, and environmental intelligence. He has researched in 52 international and Spanish research projects, some of them as head researcher. He is co-author of 4 books, co-editor of 27 proceedings books, guest editor for 8 JCR-ISI international journals, and up to 24 book chapters. He has over 450 papers published in international journals and conferences (81 of them indexed on JCR – ISI - Web of Science). He has published seven patents in the Spanish Patent and Trademark Office. He has been a supervisor on 8 Ph.D. theses (11 more are under supervision), and 130 master theses. He is the founder of The IEEE IWOBI conference series and the president of its Steering Committee, as well as the founder of both the InnoEducaTIC and APPIS conference series. He is an evaluator of project proposals for the European Union (H2020), Medical Research Council (MRC, UK), Spanish Government (ANECA, Spain), Research National Agency (ANR, France), DAAD (Germany), Argentinian Government, and the Colombian Institutions. He has been a reviewer in different indexed international journals (<70) and conferences (<250) since 2001. He has been a member of the IASTED Technical Committee on Image Processing from 2007 and a member of the IASTED Technical Committee on Artificial Intelligence and Expert Systems from 2011. \n\nHe has held the general chair position for the following: ACM-APPIS (2020, 2021), IEEE-IWOBI (2019, 2020 and 2020), A PPIS (2018, 2019), IEEE-IWOBI (2014, 2015, 2017, 2018), InnoEducaTIC (2014, 2017), IEEE-INES (2013), NoLISP (2011), JRBP (2012), and IEEE-ICCST (2005)\n\nHe is an associate editor of the Computational Intelligence and Neuroscience Journal (Hindawi – Q2 JCR-ISI). He was vice dean from 2004 to 2010 in the Higher Technical School of Telecommunication Engineers at ULPGC and the vice dean of Graduate and Postgraduate Studies from March 2013 to November 2017. He won the “Catedra Telefonica” Awards in Modality of Knowledge Transfer, 2017, 2018, and 2019 editions, and awards in Modality of COVID Research in 2020.\n\nPublic References:\nResearcher ID http://www.researcherid.com/rid/N-5967-2014\nORCID https://orcid.org/0000-0002-4621-2768 \nScopus Author ID https://www.scopus.com/authid/detail.uri?authorId=6602376272\nScholar Google https://scholar.google.es/citations?user=G1ks9nIAAAAJ&hl=en \nResearchGate https://www.researchgate.net/profile/Carlos_Travieso",institutionString:null,institution:{name:"University of Las Palmas de Gran Canaria",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null},{id:"23",title:"Computational Neuroscience",coverUrl:"https://cdn.intechopen.com/series_topics/covers/23.jpg",isOpenForSubmission:!0,annualVolume:11419,editor:{id:"14004",title:"Dr.",name:"Magnus",middleName:null,surname:"Johnsson",slug:"magnus-johnsson",fullName:"Magnus Johnsson",profilePictureURL:"https://mts.intechopen.com/storage/users/14004/images/system/14004.png",biography:"Dr Magnus Johnsson is a cross-disciplinary scientist, lecturer, scientific editor and AI/machine learning consultant from Sweden. \n\nHe is currently at Malmö University in Sweden, but also held positions at Lund University in Sweden and at Moscow Engineering Physics Institute. \nHe holds editorial positions at several international scientific journals and has served as a scientific editor for books and special journal issues. \nHis research interests are wide and include, but are not limited to, autonomous systems, computer modeling, artificial neural networks, artificial intelligence, cognitive neuroscience, cognitive robotics, cognitive architectures, cognitive aids and the philosophy of mind. \n\nDr. Johnsson has experience from working in the industry and he has a keen interest in the application of neural networks and artificial intelligence to fields like industry, finance, and medicine. \n\nWeb page: www.magnusjohnsson.se",institutionString:null,institution:{name:"Malmö University",institutionURL:null,country:{name:"Sweden"}}},editorTwo:null,editorThree:null},{id:"24",title:"Computer Vision",coverUrl:"https://cdn.intechopen.com/series_topics/covers/24.jpg",isOpenForSubmission:!0,annualVolume:11420,editor:{id:"294154",title:"Prof.",name:"George",middleName:null,surname:"Papakostas",slug:"george-papakostas",fullName:"George Papakostas",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002hYaGbQAK/Profile_Picture_1624519712088",biography:"George A. Papakostas has received a diploma in Electrical and Computer Engineering in 1999 and the M.Sc. and Ph.D. degrees in Electrical and Computer Engineering in 2002 and 2007, respectively, from the Democritus University of Thrace (DUTH), Greece. Dr. Papakostas serves as a Tenured Full Professor at the Department of Computer Science, International Hellenic University, Greece. Dr. Papakostas has 10 years of experience in large-scale systems design as a senior software engineer and technical manager, and 20 years of research experience in the field of Artificial Intelligence. Currently, he is the Head of the “Visual Computing” division of HUman-MAchines INteraction Laboratory (HUMAIN-Lab) and the Director of the MPhil program “Advanced Technologies in Informatics and Computers” hosted by the Department of Computer Science, International Hellenic University. He has (co)authored more than 150 publications in indexed journals, international conferences and book chapters, 1 book (in Greek), 3 edited books, and 5 journal special issues. His publications have more than 2100 citations with h-index 27 (GoogleScholar). His research interests include computer/machine vision, machine learning, pattern recognition, computational intelligence. \nDr. Papakostas served as a reviewer in numerous journals, as a program\ncommittee member in international conferences and he is a member of the IAENG, MIR Labs, EUCogIII, INSTICC and the Technical Chamber of Greece (TEE).",institutionString:null,institution:{name:"International Hellenic University",institutionURL:null,country:{name:"Greece"}}},editorTwo:null,editorThree:null},{id:"25",title:"Evolutionary Computation",coverUrl:"https://cdn.intechopen.com/series_topics/covers/25.jpg",isOpenForSubmission:!0,annualVolume:11421,editor:{id:"136112",title:"Dr.",name:"Sebastian",middleName:null,surname:"Ventura Soto",slug:"sebastian-ventura-soto",fullName:"Sebastian Ventura Soto",profilePictureURL:"https://mts.intechopen.com/storage/users/136112/images/system/136112.png",biography:"Sebastian Ventura is a Spanish researcher, a full professor with the Department of Computer Science and Numerical Analysis, University of Córdoba. Dr Ventura also holds the positions of Affiliated Professor at Virginia Commonwealth University (Richmond, USA) and Distinguished Adjunct Professor at King Abdulaziz University (Jeddah, Saudi Arabia). Additionally, he is deputy director of the Andalusian Research Institute in Data Science and Computational Intelligence (DaSCI) and heads the Knowledge Discovery and Intelligent Systems Research Laboratory. He has published more than ten books and over 300 articles in journals and scientific conferences. Currently, his work has received over 18,000 citations according to Google Scholar, including more than 2200 citations in 2020. In the last five years, he has published more than 60 papers in international journals indexed in the JCR (around 70% of them belonging to first quartile journals) and he has edited some Springer books “Supervised Descriptive Pattern Mining” (2018), “Multiple Instance Learning - Foundations and Algorithms” (2016), and “Pattern Mining with Evolutionary Algorithms” (2016). He has also been involved in more than 20 research projects supported by the Spanish and Andalusian governments and the European Union. He currently belongs to the editorial board of PeerJ Computer Science, Information Fusion and Engineering Applications of Artificial Intelligence journals, being also associate editor of Applied Computational Intelligence and Soft Computing and IEEE Transactions on Cybernetics. Finally, he is editor-in-chief of Progress in Artificial Intelligence. 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She is now a lecturer at the University of Witwatersrand, South Africa, and a principal researcher at the Health Economics and Epidemiology Research Office (HE2RO), South Africa. Dr. Moolla holds a Ph.D. in Psychology with her research being focused on mental health and resilience. In her professional work capacity, her research has further expanded into the fields of early childhood development, mental health, the HIV and TB care cascades, as well as COVID. She is also a UNESCO-trained International Bioethics Facilitator.",institutionString:"University of the Witwatersrand",institution:{name:"University of the Witwatersrand",country:{name:"South Africa"}}},{id:"419588",title:"Ph.D.",name:"Sergio",middleName:"Alexandre",surname:"Gehrke",slug:"sergio-gehrke",fullName:"Sergio Gehrke",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000038WgMKQA0/Profile_Picture_2022-06-02T11:44:20.jpg",biography:"Dr. Sergio Alexandre Gehrke is a doctorate holder in two fields. The first is a Ph.D. in Cellular and Molecular Biology from the Pontificia Catholic University, Porto Alegre, Brazil, in 2010 and the other is an International Ph.D. in Bioengineering from the Universidad Miguel Hernandez, Elche/Alicante, Spain, obtained in 2020. In 2018, he completed a postdoctoral fellowship in Materials Engineering in the NUCLEMAT of the Pontificia Catholic University, Porto Alegre, Brazil. He is currently the Director of the Postgraduate Program in Implantology of the Bioface/UCAM/PgO (Montevideo, Uruguay), Director of the Cathedra of Biotechnology of the Catholic University of Murcia (Murcia, Spain), an Extraordinary Full Professor of the Catholic University of Murcia (Murcia, Spain) as well as the Director of the private center of research Biotecnos – Technology and Science (Montevideo, Uruguay). Applied biomaterials, cellular and molecular biology, and dental implants are among his research interests. He has published several original papers in renowned journals. In addition, he is also a Collaborating Professor in several Postgraduate programs at different universities all over the world.",institutionString:null,institution:{name:"Universidad Católica San Antonio de Murcia",country:{name:"Spain"}}},{id:"342152",title:"Dr.",name:"Santo",middleName:null,surname:"Grace Umesh",slug:"santo-grace-umesh",fullName:"Santo Grace Umesh",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/342152/images/16311_n.jpg",biography:null,institutionString:null,institution:{name:"SRM Dental College",country:{name:"India"}}},{id:"333647",title:"Dr.",name:"Shreya",middleName:null,surname:"Kishore",slug:"shreya-kishore",fullName:"Shreya Kishore",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/333647/images/14701_n.jpg",biography:"Dr. Shreya Kishore completed her Bachelor in Dental Surgery in Chettinad Dental College and Research Institute, Chennai, and her Master of Dental Surgery (Orthodontics) in Saveetha Dental College, Chennai. She is also Invisalign certified. She’s working as a Senior Lecturer in the Department of Orthodontics, SRM Dental College since November 2019. She is actively involved in teaching orthodontics to the undergraduates and the postgraduates. Her clinical research topics include new orthodontic brackets, fixed appliances and TADs. She’s published 4 articles in well renowned indexed journals and has a published patency of her own. Her private practice is currently limited to orthodontics and works as a consultant in various clinics.",institutionString:null,institution:{name:"SRM Dental College",country:{name:"India"}}},{id:"323731",title:"Prof.",name:"Deepak M.",middleName:"Macchindra",surname:"Vikhe",slug:"deepak-m.-vikhe",fullName:"Deepak M. Vikhe",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/323731/images/13613_n.jpg",biography:"Dr Deepak M.Vikhe .\n\n\t\n\tDr Deepak M.Vikhe , completed his Masters & PhD in Prosthodontics from Rural Dental College, Loni securing third rank in the Pravara Institute of Medical Sciences Deemed University. He was awarded Dr.G.C.DAS Memorial Award for Research on Implants at 39th IPS conference Dubai (U A E).He has two patents under his name. He has received Dr.Saraswati medal award for best research for implant study in 2017.He has received Fully funded scholarship to Spain ,university of Santiago de Compostela. He has completed fellowship in Implantlogy from Noble Biocare. \nHe has attended various conferences and CDE programmes and has national publications to his credit. His field of interest is in Implant supported prosthesis. Presently he is working as a associate professor in the Dept of Prosthodontics, Rural Dental College, Loni and maintains a successful private practice specialising in Implantology at Rahata.\n\nEmail: drdeepak_mvikhe@yahoo.com..................",institutionString:null,institution:{name:"Pravara Institute of Medical Sciences",country:{name:"India"}}},{id:"204110",title:"Dr.",name:"Ahmed A.",middleName:null,surname:"Madfa",slug:"ahmed-a.-madfa",fullName:"Ahmed A. Madfa",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/204110/images/system/204110.jpg",biography:"Dr. Madfa is currently Associate Professor of Endodontics at Thamar University and a visiting lecturer at Sana'a University and University of Sciences and Technology. He has more than 6 years of experience in teaching. His research interests include root canal morphology, functionally graded concept, dental biomaterials, epidemiology and dental education, biomimetic restoration, finite element analysis and endodontic regeneration. Dr. Madfa has numerous international publications, full articles, two patents, a book and a book chapter. Furthermore, he won 14 international scientific awards. Furthermore, he is involved in many academic activities ranging from editorial board member, reviewer for many international journals and postgraduate students' supervisor. Besides, I deliver many courses and training workshops at various scientific events. Dr. Madfa also regularly attends international conferences and holds administrative positions (Deputy Dean of the Faculty for Students’ & Academic Affairs and Deputy Head of Research Unit).",institutionString:"Thamar University",institution:null},{id:"210472",title:"Dr.",name:"Nermin",middleName:"Mohammed Ahmed",surname:"Yussif",slug:"nermin-yussif",fullName:"Nermin Yussif",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/210472/images/system/210472.jpg",biography:"Dr. Nermin Mohammed Ahmed Yussif is working at the Faculty of dentistry, University for October university for modern sciences and arts (MSA). Her areas of expertise include: periodontology, dental laserology, oral implantology, periodontal plastic surgeries, oral mesotherapy, nutrition, dental pharmacology. She is an editor and reviewer in numerous international journals.",institutionString:"MSA University",institution:null},{id:"204606",title:"Dr.",name:"Serdar",middleName:null,surname:"Gözler",slug:"serdar-gozler",fullName:"Serdar Gözler",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/204606/images/system/204606.jpeg",biography:"Dr. Serdar Gözler has completed his undergraduate studies at the Marmara University Faculty of Dentistry in 1978, followed by an assistantship in the Prosthesis Department of Dicle University Faculty of Dentistry. Starting his PhD work on non-resilient overdentures with Assoc. Prof. Hüsnü Yavuzyılmaz, he continued his studies with Prof. Dr. Gürbüz Öztürk of Istanbul University Faculty of Dentistry Department of Prosthodontics, this time on Gnatology. He attended training programs on occlusion, neurology, neurophysiology, EMG, radiology and biostatistics. In 1982, he presented his PhD thesis \\Gerber and Lauritzen Occlusion Analysis Techniques: Diagnosis Values,\\ at Istanbul University School of Dentistry, Department of Prosthodontics. As he was also working with Prof. Senih Çalıkkocaoğlu on The Physiology of Chewing at the same time, Gözler has written a chapter in Çalıkkocaoğlu\\'s book \\Complete Prostheses\\ entitled \\The Place of Neuromuscular Mechanism in Prosthetic Dentistry.\\ The book was published five times since by the Istanbul University Publications. Having presented in various conferences about occlusion analysis until 1998, Dr. Gözler has also decided to use the T-Scan II occlusion analysis method. Having been personally trained by Dr. Robert Kerstein on this method, Dr. Gözler has been lecturing on the T-Scan Occlusion Analysis Method in conferences both in Turkey and abroad. Dr. Gözler has various articles and presentations on Digital Occlusion Analysis methods. He is now Head of the TMD Clinic at Prosthodontic Department of Faculty of Dentistry , Istanbul Aydın University , Turkey.",institutionString:"Istanbul Aydin University",institution:{name:"Istanbul Aydın University",country:{name:"Turkey"}}},{id:"240870",title:"Ph.D.",name:"Alaa Eddin Omar",middleName:null,surname:"Al Ostwani",slug:"alaa-eddin-omar-al-ostwani",fullName:"Alaa Eddin Omar Al Ostwani",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/240870/images/system/240870.jpeg",biography:"Dr. Al Ostwani Alaa Eddin Omar received his Master in dentistry from Damascus University in 2010, and his Ph.D. in Pediatric Dentistry from Damascus University in 2014. Dr. Al Ostwani is an assistant professor and faculty member at IUST University since 2014. \nDuring his academic experience, he has received several awards including the scientific research award from the Union of Arab Universities, the Syrian gold medal and the international gold medal for invention and creativity. Dr. Al Ostwani is a Member of the International Association of Dental Traumatology and the Syrian Society for Research and Preventive Dentistry since 2017. He is also a Member of the Reviewer Board of International Journal of Dental Medicine (IJDM), and the Indian Journal of Conservative and Endodontics since 2016.",institutionString:"International University for Science and Technology.",institution:{name:"Islamic University of Science and Technology",country:{name:"India"}}},{id:"42847",title:"Dr.",name:"Belma",middleName:null,surname:"Işik Aslan",slug:"belma-isik-aslan",fullName:"Belma Işik Aslan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/42847/images/system/42847.jpg",biography:"Dr. Belma IşIk Aslan was born in 1976 in Ankara-TURKEY. After graduating from TED Ankara College in 1994, she attended to Gazi University, Faculty of Dentistry in Ankara. She completed her PhD in orthodontic education at Gazi University between 1999-2005. Dr. Işık Aslan stayed at the Providence Hospital Craniofacial Institude and Reconstructive Surgery in Michigan, USA for three months as an observer. She worked as a specialist doctor at Gazi University, Dentistry Faculty, Department of Orthodontics between 2005-2014. She was appointed as associate professor in January, 2014 and as professor in 2021. Dr. Işık Aslan still works as an instructor at the same faculty. She has published a total of 35 articles, 10 book chapters, 39 conference proceedings both internationally and nationally. Also she was the academic editor of the international book 'Current Advances in Orthodontics'. She is a member of the Turkish Orthodontic Society and Turkish Cleft Lip and Palate Society. She is married and has 2 children. Her knowledge of English is at an advanced level.",institutionString:"Gazi University Dentistry Faculty Department of Orthodontics",institution:null},{id:"178412",title:"Associate Prof.",name:"Guhan",middleName:null,surname:"Dergin",slug:"guhan-dergin",fullName:"Guhan Dergin",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/178412/images/6954_n.jpg",biography:"Assoc. Prof. Dr. Gühan Dergin was born in 1973 in Izmit. He graduated from Marmara University Faculty of Dentistry in 1999. He completed his specialty of OMFS surgery in Marmara University Faculty of Dentistry and obtained his PhD degree in 2006. In 2005, he was invited as a visiting doctor in the Oral and Maxillofacial Surgery Department of the University of North Carolina, USA, where he went on a scholarship. Dr. Dergin still continues his academic career as an associate professor in Marmara University Faculty of Dentistry. He has many articles in international and national scientific journals and chapters in books.",institutionString:null,institution:{name:"Marmara University",country:{name:"Turkey"}}},{id:"178414",title:"Prof.",name:"Yusuf",middleName:null,surname:"Emes",slug:"yusuf-emes",fullName:"Yusuf Emes",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/178414/images/6953_n.jpg",biography:"Born in Istanbul in 1974, Dr. Emes graduated from Istanbul University Faculty of Dentistry in 1997 and completed his PhD degree in Istanbul University faculty of Dentistry Department of Oral and Maxillofacial Surgery in 2005. He has papers published in international and national scientific journals, including research articles on implantology, oroantral fistulas, odontogenic cysts, and temporomandibular disorders. Dr. Emes is currently working as a full-time academic staff in Istanbul University faculty of Dentistry Department of Oral and Maxillofacial Surgery.",institutionString:null,institution:{name:"Istanbul University",country:{name:"Turkey"}}},{id:"192229",title:"Ph.D.",name:"Ana Luiza",middleName:null,surname:"De Carvalho Felippini",slug:"ana-luiza-de-carvalho-felippini",fullName:"Ana Luiza De Carvalho Felippini",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/192229/images/system/192229.jpg",biography:null,institutionString:"University of São Paulo",institution:{name:"University of Sao Paulo",country:{name:"Brazil"}}},{id:"256851",title:"Prof.",name:"Ayşe",middleName:null,surname:"Gülşen",slug:"ayse-gulsen",fullName:"Ayşe Gülşen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/256851/images/9696_n.jpg",biography:"Dr. Ayşe Gülşen graduated in 1990 from Faculty of Dentistry, University of Ankara and did a postgraduate program at University of Gazi. \nShe worked as an observer and research assistant in Craniofacial Surgery Departments in New York, Providence Hospital in Michigan and Chang Gung Memorial Hospital in Taiwan. \nShe works as Craniofacial Orthodontist in Department of Aesthetic, Plastic and Reconstructive Surgery, Faculty of Medicine, University of Gazi, Ankara Turkey since 2004.",institutionString:"Univeristy of Gazi",institution:null},{id:"255366",title:"Prof.",name:"Tosun",middleName:null,surname:"Tosun",slug:"tosun-tosun",fullName:"Tosun Tosun",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/255366/images/7347_n.jpg",biography:"Graduated at the Faculty of Dentistry, University of Istanbul, Turkey in 1989;\nVisitor Assistant at the University of Padua, Italy and Branemark Osseointegration Center of Treviso, Italy between 1993-94;\nPhD thesis on oral implantology in University of Istanbul and was awarded the academic title “Dr.med.dent.”, 1997;\nHe was awarded the academic title “Doç.Dr.” (Associated Professor) in 2003;\nProficiency in Botulinum Toxin Applications, Reading-UK in 2009;\nMastership, RWTH Certificate in Laser Therapy in Dentistry, AALZ-Aachen University, Germany 2009-11;\nMaster of Science (MSc) in Laser Dentistry, University of Genoa, Italy 2013-14.\n\nDr.Tosun worked as Research Assistant in the Department of Oral Implantology, Faculty of Dentistry, University of Istanbul between 1990-2002. \nHe worked part-time as Consultant surgeon in Harvard Medical International Hospitals and John Hopkins Medicine, Istanbul between years 2007-09.\u2028He was contract Professor in the Department of Surgical and Diagnostic Sciences (DI.S.C.), Medical School, University of Genova, Italy between years 2011-16. \nSince 2015 he is visiting Professor at Medical School, University of Plovdiv, Bulgaria. \nCurrently he is Associated Prof.Dr. at the Dental School, Oral Surgery Dept., Istanbul Aydin University and since 2003 he works in his own private clinic in Istanbul, Turkey.\u2028\nDr.Tosun is reviewer in journal ‘Laser in Medical Sciences’, reviewer in journal ‘Folia Medica\\', a Fellow of the International Team for Implantology, Clinical Lecturer of DGZI German Association of Oral Implantology, Expert Lecturer of Laser&Health Academy, Country Representative of World Federation for Laser Dentistry, member of European Federation of Periodontology, member of Academy of Laser Dentistry. Dr.Tosun presents papers in international and national congresses and has scientific publications in international and national journals. He speaks english, spanish, italian and french.",institutionString:null,institution:{name:"Istanbul Aydın University",country:{name:"Turkey"}}},{id:"171887",title:"Prof.",name:"Zühre",middleName:null,surname:"Akarslan",slug:"zuhre-akarslan",fullName:"Zühre Akarslan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/171887/images/system/171887.jpg",biography:"Zühre Akarslan was born in 1977 in Cyprus. She graduated from Gazi University Faculty of Dentistry, Ankara, Turkey in 2000. \r\nLater she received her Ph.D. degree from the Oral Diagnosis and Radiology Department; which was recently renamed as Oral and Dentomaxillofacial Radiology, from the same university. \r\nShe is working as a full-time Associate Professor and is a lecturer and an academic researcher. \r\nHer expertise areas are dental caries, cancer, dental fear and anxiety, gag reflex in dentistry, oral medicine, and dentomaxillofacial radiology.",institutionString:"Gazi University",institution:{name:"Gazi University",country:{name:"Turkey"}}},{id:"256417",title:"Associate Prof.",name:"Sanaz",middleName:null,surname:"Sadry",slug:"sanaz-sadry",fullName:"Sanaz Sadry",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/256417/images/8106_n.jpg",biography:null,institutionString:null,institution:null},{id:"272237",title:"Dr.",name:"Pinar",middleName:"Kiymet",surname:"Karataban",slug:"pinar-karataban",fullName:"Pinar Karataban",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/272237/images/8911_n.png",biography:"Assist.Prof.Dr.Pınar Kıymet Karataban, DDS PhD \n\nDr.Pınar Kıymet Karataban was born in Istanbul in 1975. After her graduation from Marmara University Faculty of Dentistry in 1998 she started her PhD in Paediatric Dentistry focused on children with special needs; mainly children with Cerebral Palsy. She finished her pHD thesis entitled \\'Investigation of occlusion via cast analysis and evaluation of dental caries prevalance, periodontal status and muscle dysfunctions in children with cerebral palsy” in 2008. She got her Assist. Proffessor degree in Istanbul Aydın University Paediatric Dentistry Department in 2015-2018. ın 2019 she started her new career in Bahcesehir University, Istanbul as Head of Department of Pediatric Dentistry. In 2020 she was accepted to BAU International University, Batumi as Professor of Pediatric Dentistry. She’s a lecturer in the same university meanwhile working part-time in private practice in Ege Dental Studio (https://www.egedisklinigi.com/) a multidisciplinary dental clinic in Istanbul. Her main interests are paleodontology, ancient and contemporary dentistry, oral microbiology, cerebral palsy and special care dentistry. She has national and international publications, scientific reports and is a member of IAPO (International Association for Paleodontology), IADH (International Association of Disability and Oral Health) and EAPD (European Association of Pediatric Dentistry).",institutionString:null,institution:null},{id:"202198",title:"Dr.",name:"Buket",middleName:null,surname:"Aybar",slug:"buket-aybar",fullName:"Buket Aybar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/202198/images/6955_n.jpg",biography:"Buket Aybar, DDS, PhD, was born in 1971. She graduated from Istanbul University, Faculty of Dentistry, in 1992 and completed her PhD degree on Oral and Maxillofacial Surgery in Istanbul University in 1997.\nDr. Aybar is currently a full-time professor in Istanbul University, Faculty of Dentistry Department of Oral and Maxillofacial Surgery. She has teaching responsibilities in graduate and postgraduate programs. Her clinical practice includes mainly dentoalveolar surgery.\nHer topics of interest are biomaterials science and cell culture studies. She has many articles in international and national scientific journals and chapters in books; she also has participated in several scientific projects supported by Istanbul University Research fund.",institutionString:null,institution:null},{id:"260116",title:"Dr.",name:"Mehmet",middleName:null,surname:"Yaltirik",slug:"mehmet-yaltirik",fullName:"Mehmet Yaltirik",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/260116/images/7413_n.jpg",biography:"Birth Date 25.09.1965\r\nBirth Place Adana- Turkey\r\nSex Male\r\nMarrial Status Bachelor\r\nDriving License Acquired\r\nMother Tongue Turkish\r\n\r\nAddress:\r\nWork:University of Istanbul,Faculty of Dentistry, Department of Oral Surgery and Oral Medicine 34093 Capa,Istanbul- TURKIYE",institutionString:null,institution:null},{id:"172009",title:"Dr.",name:"Fatma Deniz",middleName:null,surname:"Uzuner",slug:"fatma-deniz-uzuner",fullName:"Fatma Deniz Uzuner",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/172009/images/7122_n.jpg",biography:"Dr. Deniz Uzuner was born in 1969 in Kocaeli-TURKEY. After graduating from TED Ankara College in 1986, she attended the Hacettepe University, Faculty of Dentistry in Ankara. \nIn 1993 she attended the Gazi University, Faculty of Dentistry, Department of Orthodontics for her PhD education. After finishing the PhD education, she worked as orthodontist in Ankara Dental Hospital under the Turkish Government, Ministry of Health and in a special Orthodontic Clinic till 2011. Between 2011 and 2016, Dr. Deniz Uzuner worked as a specialist in the Department of Orthodontics, Faculty of Dentistry, Gazi University in Ankara/Turkey. In 2016, she was appointed associate professor. Dr. Deniz Uzuner has authored 23 Journal Papers, 3 Book Chapters and has had 39 oral/poster presentations. She is a member of the Turkish Orthodontic Society. Her knowledge of English is at an advanced level.",institutionString:null,institution:null},{id:"332914",title:"Dr.",name:"Muhammad Saad",middleName:null,surname:"Shaikh",slug:"muhammad-saad-shaikh",fullName:"Muhammad Saad Shaikh",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Jinnah Sindh Medical University",country:{name:"Pakistan"}}},{id:"315775",title:"Dr.",name:"Feng",middleName:null,surname:"Luo",slug:"feng-luo",fullName:"Feng Luo",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Sichuan University",country:{name:"China"}}},{id:"423519",title:"Dr.",name:"Sizakele",middleName:null,surname:"Ngwenya",slug:"sizakele-ngwenya",fullName:"Sizakele Ngwenya",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of the Witwatersrand",country:{name:"South Africa"}}},{id:"419270",title:"Dr.",name:"Ann",middleName:null,surname:"Chianchitlert",slug:"ann-chianchitlert",fullName:"Ann Chianchitlert",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Walailak University",country:{name:"Thailand"}}},{id:"419271",title:"Dr.",name:"Diane",middleName:null,surname:"Selvido",slug:"diane-selvido",fullName:"Diane Selvido",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Walailak University",country:{name:"Thailand"}}},{id:"419272",title:"Dr.",name:"Irin",middleName:null,surname:"Sirisoontorn",slug:"irin-sirisoontorn",fullName:"Irin Sirisoontorn",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Walailak University",country:{name:"Thailand"}}},{id:"355660",title:"Dr.",name:"Anitha",middleName:null,surname:"Mani",slug:"anitha-mani",fullName:"Anitha Mani",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"SRM Dental College",country:{name:"India"}}},{id:"355612",title:"Dr.",name:"Janani",middleName:null,surname:"Karthikeyan",slug:"janani-karthikeyan",fullName:"Janani Karthikeyan",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"SRM Dental College",country:{name:"India"}}},{id:"334400",title:"Dr.",name:"Suvetha",middleName:null,surname:"Siva",slug:"suvetha-siva",fullName:"Suvetha Siva",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"SRM Dental College",country:{name:"India"}}}]}},subseries:{item:{id:"90",type:"subseries",title:"Human Development",keywords:"Neuroscientific research, Brain functions, Human development, UN’s human development index, Self-awareness, Self-development",scope:"