\r\n\tThe surgical approach to prostate cancer is traditionally considered a milestone in the treatment of this disease. To date, minimally invasive procedures like laparoscopy and robotic surgery are a gold-standard and will be described in the book. Also, there is a growing interest among the investigators on conservative techniques. For this reason, there are chapters on non-surgical techniques, like radiotherapy and brachitherapy and on experimental techniques, like high-intensity focused ultrasound or electroporation. \r\n\tIt is well known that the key to success in treatment of prostate cancer is the ability to perform the best treatment available, but not all patients are good candidates to the same treatment. This book intends to provide the reader with a comprehensive overview of the wide range of treatments available for prostate cancer and aims to give more insight on the opportunities related to a multimodal approach.
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1. Introduction
Taxes play an important role in the country’s economic policy. They represent one of the basic revenues of the state budget or municipal budgets. Every tax has its justification in the tax system and fulfills a certain role. The fact is that tax issues are very extensive and demanding, and therefore, the objective of tax optimization is to create a tax system that is simple and optimal for each business subject [16]. The fundamental problem of EU in area of taxes is tax harmonization and tax competition in the European Union [15]. Basic institutes of the tax process are important tools that affect the tax process of business subjects and have a significant impact on the quantification of the tax base and the amount of tax liability [1]. The basic prerequisite for improving the business environment is the regulation of laws in terms of support for entrepreneurs so as to find an optimal balance between tax revenues, that is, the tax burden on business subjects and the attractiveness of the country for labor and capital. The tax administration should respond to the current difficult economic conditions, and that is why it changes its anti-tax strategy and focuses on new areas. The business area is still struggling to meet all tax obligations while trying to create added value in business [14]. An important reality of the business environment is to know all laws and to use legal tools to optimize the tax base. The strategic goal of business is to optimize the tax base and business with value added and tax reduction in all areas of taxes. Multimodal transport is an opportunity for a more ecological approach to the environment in EU states and total exemption of vehicle tax [13], and such opportunities create space for creative business (Table 1).
The tax-deductible burden expresses how high the rate of taxation is or what part of GDP is made up of paid taxes and levies. How many resources are available to the country for redistribution through public finances? The Paying Taxes study 2017 shows the tax burden on companies in Slovakia, which is 10% higher than the global average and EU/EFTA average. Basic macroeconomic indicators associated with fiscal burden measurement include tax quota 1, tax quota 2, tax multiplier, expenditure multiplier, and multiplier of balanced budget. The tax quota is a macroeconomic indicator that does not reflect the impact of tax and levy on economic entities and individuals but pursues the country’s priority objective of achieving the highest tax revenues that form the fiscal policy instrument and is the main source of revenue for the state budget (Table 2, Figure 1).
Years
DK I (%)
DK II (%)
1995
24.8
39.6
1996
23.0
38.7
1997
21.9
36.6
1998
21.5
36.2
1999
21.2
35.1
2000
19.8
33.8
2001
18.7
32.9
2002
18.4
32.9
2003
19.0
32.7
2004
18.6
31.6
2005
18.8
31.4
2006
17.5
29.2
2007
17.4
29.0
2008
17.1
28.8
2009
16.3
28.8
2010
15.8
28.1
2011
16.3
28.6
2012
15.7
28.2
2013
16.7
30.2
2014
17.5
31.1
2015
18.1
32.1
Table 2.
Taxes quota in Slovakia.
Source: Eurostat.
Figure 1.
Trend of tax quota in Slovakia. Source: Eurostat.
The World Bank Group and the consulting firm PwC have released a study aimed at simplifying and reducing tax liabilities in business around the world. The study involved 190 countries of the world. The study highlighted the global most common element of tax reforms over the period under review for the introduction of an electronic system for filling in and paying taxes.
3. Tax rates of direct taxes in Slovakia
Tax rates are a fundamental competitive tool and a means of tax harmonization. Setting tax rates is the responsibility of individual EU states, hindering tax harmonization in the EU. Tax rates are an indicator of differences in tax systems across EU countries. We determine the tax rate in terms of income of a natural person and a legal entity. The natural person uses the tax rate based on the tax base reduced by non-taxable parts and the tax loss and the special rate of income tax on the dependent activity of selected constitutional agents, whose income is also taxed at this special rate (the President of SR, Member of the Slovak Republic, and the Vice-Chairman of the Supreme Audit Office of the Slovak Republic) [7]. The tax rate is based on 176.8 times the current living wage (Table 3).
The tax liability of a legal person is determined from the tax base reduced by the tax loss according to the applicable tax rate. The legal entity was required to pay the tax license for the first time in 2015 for the taxable period of 2014 as the minimum corporate income tax. The new tax law, which will enter into force on January 1, 2018, will be cancelled, the last taxable period for which taxpayers-legal entities will be required to pay tax licenses will be 2017 if the tax year is a calendar year. If the taxpayer is not a taxable person on the last day of the taxable period and has an annual turnover not exceeding EUR 500,000, a tax license of EUR 480 shall apply. If the taxpayer is a value added taxer at the last taxable date and has an annual turnover not exceeding EUR 500,000, he pays a tax license of EUR 960. If the taxpayer attains an annual turnover of more than EUR 500,000 at the last taxable date, regardless of whether or not he is a taxable person, he has a tax license of EUR 2880 (Table 4).
The natural reaction of each business entity to taxing is the search for tax optimization within legal procedures. In order to minimize the indirect tax liability, entrepreneurs may consider the decision on voluntary registration as a value added tax payer. In order to minimize the tax burden on local taxes, entrepreneurs consider regional differentiated tax burdens. In the case of income tax, entrepreneurs consider decisions of long-term nature, including choosing a suitable form of business, choosing the way to apply tax expenses, choosing the way to procure long-term tangible and intangible assets, choosing the depreciation method and using the possibility of aborting the depreciation, non-taxable and deductible items from the tax base, the possibility of applying the tax deducted as a tax advance. Income tax in the Slovak legal system is a common denomination for two types of taxes: the income tax of a natural person and the corporate income tax. Many EU countries complain that some Member States have an unfair advantage from low corporate tax rates. Their aim is to determine the minimum rate of tax within the European Union. In Switzerland, Spain, Italy, England and Austria, income tax has always been relatively high. Taxes have set these countries virtually exclusively on the basis of their national needs. The tax rates in Bulgaria, Cyprus, Romania, Hungary and the Czech Republic had to be set to motivate Western European companies to shift production (Figure 2).
Figure 2.
Tax rates of income. Source: Ref. [9].
Taxation of the economic activity of business entities can be judged at a double level. One is the effort of the state and the self-government to maximize revenue into public budgets that needs to be taken into account in the context of the impact of individual taxes on the behavior of taxpayers and the entire society. The second is the interests of taxpayers and their attitudes toward taxation. Tax harmonization exists where taxpayers face similar or equal tax rates regardless of whether they are working, buying, buying or investing. Harmonized tax rates eliminate budget competition. Tax harmonization can be achieved in two different ways: explicit and implicit tax harmonization. Explicit tax harmonization occurs when countries agree to set minimum or equal tax rates. The EU requires its Member States to apply a minimum standard rate of 15% VAT. The EU has harmonized taxes on fuels, spirits and tobacco, and efforts to harmonize corporate and personal income taxes. In such a direct form of tax harmonization, taxpayers are not able to benefit from better tax policy in other countries, and governments are not under the pressure of competitive discipline. Tax competition is desirable for many reasons. The most important thing is that it underpins economic growth by encouraging policy-makers to make a meaningful tax policy.
4. Limit on tax return
Tax return is the document FO, PO. Its purpose is to grant income that is subject to tax. The result is a quantification of the tax, which can be compared with the tax advances paid. The resulting tax arrears FO, PO will transfer the state through the tax office. Tax return always refers to a certain period, calendar year, marketing year and specific tax, income tax, value added tax (Table 5) [9].
For tax purposes, two types of tax returns are available: type A and type B. Type A is intended for taxpayers who have income only from dependent activity under Section 5 of the Income Tax Act. Type B is intended for taxpayers who have income, which are subject to tax according to §5 to §8 of the Income Tax Act. Tax returns are required to be paid by natural persons whose income for the taxable period exceeds 50% of the amount of the taxable amount of tax to the taxpayer if the income derived from the non-taxpayer receives income from abroad, the revenue for which tax cannot be deducted and also if the taxpayer did not ask the employer to perform the annual settlement of deductions for tax on dependent activity. The tax return is required to be paid by an employee who has income from dependent activity from several employers or other types of taxable income. Tax returns are required to be filed by natural persons whose earnings for a taxable period do not exceed 50% of the taxable amount of tax on the taxpayer but show a tax loss. The tax return is also filed by a lawyer, a PO person (Figure 3).
Figure 3.
Trend of limit value of tax returns. Source: Ref. [9].
5. Tax indicators in Slovakia
The term non-taxable portion of the taxable amount is the statutory value for tax purposes of the taxpayer’s tax base, which is based on the subsistence level. The amount of the tax base is related to the amount of the non-taxable portion. The Income Tax sets a limit of 100 times the amount of the applicable living wage. If the tax base is lower or equal to 100 times the living wage, the non-taxable portion of the tax base per year is calculated at 19.2 multiple of living wage. If the taxable amount of the taxpayer’s tax exceeds the amount of 100 times of living wage, the non-taxable portion of the taxable amount is calculated as the difference of 44.2 times of living wage and ¼ of the tax base. If the result is equal to or less than zero, the non-taxable portion is zero. The non-taxable amount of the taxable amount of the taxable person cannot be claimed by the taxpayer who, from the beginning of the tax period (from 1 January), receives a retirement pension, early retirement pension, social security reimbursement premium, old-age pension, retirement pension or foreign compulsory insurance pension, to whom a retirement pension has been redeemed at the beginning of the current or previous tax period (calendar year), and at the same time, if his or her pension is higher than the non-taxable portion of the taxable person’s tax base. Where the amount of the retirement pension is lower than the amount of the taxable amount of the taxable amount of the taxable amount, the taxpayer is entitled to claim only the difference between the non-taxable portion of the taxable amount of the taxpayer and the retirement pension (Table 6).
Non-taxable portion of the tax base
Non-taxable portion of the tax base of the taxpayer
Non-taxable portion of the taxable income of the spouse (spouse)
Non-taxable portion of the tax base for contributions to supplementary retirement savings (third pillar)
5.1. Non-taxable portion of the tax base on wife, husband
In this type of non-taxable part, the income of his wife, husband is assessed in addition to the taxable person’s tax base, which fulfills at least one of the following conditions during the period: she takes care of a child living in common household, she was unemployed, she is a person with a disability, she tooks a care allowance. Include every income, including income tax, maternity and sickness benefits, all kinds of pensions and prizes, between the wife’s (our husband’s) incomes. This revenue is reduced by compulsory premiums paid and contributions to health and social insurance. We do not include an employee’s bonus, tax bonus, retirement pension, state social benefits in our wife’s (our husband’s) income. State social benefits include childbirth allowance and surcharge for birth grant, contribution to parents who are simultaneously born with three or more children or who have been repeatedly born twins or more children over the course of 2 years at the same time, a funeral grant, parental allowance, child allowance and surcharge for baby allowance, Christmas contribution to pensioners, retirement allowance by political prisoners.
5.2. Non-taxable portion of the tax base for contributions to supplementary retirement savings (third pillar)
It is a part of the taxpayer’s contribution to supplementary retirement savings (up to the third pillar). The non-deductible part of the tax base also includes contributions to supplementary pension savings abroad of the same or similar type. The maximum amount of this non-taxable portion is €180 for a taxable period. This amount is fixed by the Income Tax Act. The limit applies to all taxpayers (domestic and foreign employees, tradesmen, etc.) as well.
In order to claim this taxable amount, the taxpayer has to meet the following conditions: the participant under which he paid contributions for supplementary pension savings was concluded after December 31, 2013 or was amended and the change in the plan was canceled, the taxpayer has not entered into a contract with another participant who does not meet the conditions laid down by the law on supplementary retirement savings (Figure 4).
Figure 4.
Trend of non-taxable portion in Slovakia. Source: Ref. [9].
The development of a non-taxable portion of the tax base is based on the development of the subsistence level. The minimum age has not changed for the last 4 years, and therefore there has been no change in the taxable portion of the tax base. The non-taxable portion of the tax base affects the amount of tax liability of business entities and individuals. This is a legal form of tax deduction, which the taxpayer optimizes the tax base.
The taxpayer is entitled to claim a non-taxable portion of the tax base only from the sub-base of the tax on income from dependent activity, business income, other self-employment, rental, use of the work and artistic performance.
5.3. Living wage
The subsistence minimum is defined as the socially recognized minimum income threshold for a natural person under whom a state of material need arises. The subsistence sums are adjusted each year to July 1 of the current calendar year. If the legislation does not change, to 30.6. it is repeat date every year by the Ministry of Labour, Social Affairs and the family of the Slovak Republic [5, 9, 10]. The sum of the subsistence minimum is a relatively important reference (Figure 5).
Figure 5.
Trend of living wage in Slovakia. Source: Ref. [10].
The subsistence sums help in a universal way to find out in what financial situation the persons under review are located. The subsistence amount for one adult physical person, or the coefficient increasing this amount affects a number of other indicators in the tax and social spheres. These include, for example, the amount of the tax bonus, the amount of non-taxable portions of the tax base, the amount of the tax base, after which the individual has to apply a higher rate of income tax (25%), the amount of the allowance and the surcharge for the child allowance, the amount of the unreachable amount for the execution charges [6, 9, 10]. The above minimum subsistence also affects the entitlement to early retirement or the minimum retirement age (Table 7).
The minimum wage is determined on the basis of key factors that affect it. Basic factors influence determination of minimum wage are economic and social situation in the country, consumer price developments, employment developments, average monthly wage developments in the national economy, and the development of the subsistence minimum. The concept of the minimum wage is the lowest possible wage that must be paid to the employee for a work-related or similar employment relationship to ensure the minimum level of employee’s income for the work done but also for the natural persons performing for the employer under one of the agreements on work performed outside the employment (work agreement, agreement on students’ brigade work) [11]. The amount of the minimum wage is set by the Government of the Slovak Republic each year by two amounts: in euros per month (monthly minimum wage) and in euro per hour worked (hourly minimum wage). The amount of the monthly minimum wage applies only to employees who are remunerated in the form of a monthly wage. Employees who are remunerated by another form of wage, such as monthly wages (hourly wages), are based on the hourly minimum wage when assessing their legal entitlements to wage levels. If the employee has a shorter than the prescribed weekly working time or does not work all the working days or hours in the month, the monthly minimum wage is reduced in proportion between the actual times worked and the monthly working time fund. The amount of the minimum wage in euro per month is rounded to the nearest 10 eurocent (Table 8) [11].
The minimum wage is not established in Finland, Austria, Denmark, Italy, Malta and Cyprus. Among the most advanced countries where the minimum wage is the highest are Luxembourg, Ireland, the Netherlands, Belgium, Germany and France (Table 9).
Country
Minimum wage
Luxembourg
1999 €
Ireland
1563 €
The Netherlands
1552 €
Belgium
1533 €
Germany
1486 €
France
1482 €
England
1400 €
Spain
825 €
Slovenia
804 €
Malta
735 €
Greece
684 €
Portugal
650 €
Estonia
470 €
Poland
454 €
Slovakia
435 €
Hungary
410 €
Croatia
410 €
The Czech Republic
408 €
Latvia
382 €
Lithuania
381 €
Romania
274 €
Bulgaria
220 €
Table 9.
Minimum wage in Europa.
Source: Eurostat.
The purpose of setting a minimum wage is to protect employees and employers. The minimum wage fulfills two basic functions—social protection—the minimum wage must ensure to employee socially acceptable of wage - minimum in height of living wage. And ensures wage competition - adequate labor assessment economically critical - the minimum wage motivate people to work, not to take social benefits, to protect employees againts unfair competition on the labor market. The minimum wage in Slovakia has been growing steadily since 2003 (Figure 6).
Figure 6.
Trend of minimum wage in Slovakia.
The national minimum wage has 22 states from the 28 EU Member States, with the exception of Denmark, Italy, Cyprus, Austria, Finland and Sweden. When comparing EU countries and outside the Eurozone, the minimum wage is influenced mainly by the level of the exchange rate between the national currency and the Euro. The differences between the minimum wage levels in the EU countries are striking. The maximum difference in the minimum wage recorded in the EU countries is € 1729. Within EU countries, it is not always clear that the minimum wage is valid on a monthly basis; some countries may have it on an hourly or weekly basis.
5.5. Tax bonus
We understand the tax bonus as a tax concession or tax benefit, which is provided to a taxpayer who is living with a child, in the form of a reduction in income tax or tax advances that the taxpayer would otherwise have to pay. For the purposes of the tax bonus, a child may not have the same permanent residence as a taxpayer. The temporary stay of a child outside the household (e.g., a child studying in another city and staying on board) does not affect the application of the tax bonus. The law does not require the same taxpayer’s and child’s residence, but that the taxpayer and the child live in one household. In accordance with Section 115 of the Civil Code, households are natural persons who live together and share the costs of their needs together (Table 10).
The amount that a taxpayer reduces the tax can be seen as a tax credit or tax benefit to the person who receives it after the specified conditions have been met, the amount of the tax bonus is reduced by the tax (not the tax base). It can be claimed by a taxpayer who has had taxable income in the taxable period: from dependent activity, at least six times the minimum wage or from business, other self-employment and from renting six times the minimum wage and reported the tax base (the tax base from of revenue); only one taxpayer may apply if the conditions for applying the tax bonus are met by more taxpayers and, unless otherwise agreed, the tax bonus for all dependent children is applied or awarded in the following order: mother, father, other eligible person; the taxpayer can apply the tax bonus even if the child has a temporary residence outside the household, for example, if the child is studying at secondary school outside of his/her permanent residence, and he/she is staying at the boarding school (Figure 7).
Figure 7.
Trend of tax bonus in Slovakia. Source: Ref. [9].
6. Impact of taxes to business sector
The business environment is characterized by constant changes in the law, resulting in legislative uncertainty. Businessmen in Slovakia must constantly observe what changes they are about and how they will affect their business. Their attention is not entirely entrepreneurial because they have to deal with different bureaucratic requirements, but also with accounting and legal problems. Business costs are increasing, which negatively affects their competitiveness and leads to the demotivation of business expansion, innovation or improvement of their services. In order to maintain economic growth in Slovakia, it is necessary to improve the business environment, thereby increasing employment, but also booming small- and medium-sized enterprises, especially in the case of economically weaker regions. The need to remove administrative and regulatory barriers in the business sector is a priority for economic growth (Figure 8).
Figure 8.
Barriers in business in Slovakia. Source: Research in Slovakia.
7. Summary
The tax policy of the country must have a direction in terms of supporting the business environment in Slovakia. Within fiscal policy, macroeconomic objectives are mainly focused on securing funds to cover state spending, on the possibility of influencing the economic and social policy of the state, on ensuring the interplay of taxes on the stability of the currency, on credit and monetary policy and on unemployment, the problems of tax problems, their conception and structure in the state economy. In addition to the macroeconomic perception of the importance of taxes, the microeconomic point of view, which monitors changes in tax laws and their impact on business entities, influences the tax base by legal instruments of tax policy (depreciation policy), items affecting the tax base of economic subjects (e.g., non-taxable items). The development of the basic institutes of the tax process points to the support of the business environment in Slovakia. Trend analyses of the main institutes of the tax process show slight fluctuations over the 10-year period under review, despite slight changes in core institutes. Basic institutes are tools for optimizing the tax base, which affects the business of natural and legal persons in Slovakia. The tax policy of the country has a flexible response to the necessary changes in every area of social life; it should focus on solving problems related to the tax burden on entrepreneurs, in order to avoid, for example, double taxation, which is gradually being addressed through the introduction of double taxation treaties.
\n',keywords:"taxes, tax process, tax administration, basic institutes, taxes indicator",chapterPDFUrl:"https://cdn.intechopen.com/pdfs/59364.pdf",chapterXML:"https://mts.intechopen.com/source/xml/59364.xml",downloadPdfUrl:"/chapter/pdf-download/59364",previewPdfUrl:"/chapter/pdf-preview/59364",totalDownloads:1013,totalViews:171,totalCrossrefCites:1,totalDimensionsCites:1,totalAltmetricsMentions:0,impactScore:0,impactScorePercentile:1,impactScoreQuartile:1,hasAltmetrics:0,dateSubmitted:"July 31st 2017",dateReviewed:"January 24th 2018",datePrePublished:"February 16th 2018",datePublished:"April 20th 2018",dateFinished:"February 15th 2018",readingETA:"0",abstract:"The tax policy of the country must have a direction in terms of supporting the business environment in Slovakia. Within fiscal policy, macroeconomic objectives are mainly focused on securing funds to cover state spending on the possibility of influencing the economic and social policies of the state, on ensuring the interplay of taxes on the stability of the currency, on credit and monetary policy and on unemployment, the problems of tax problems, their conception and structure in the state economy. In addition to the macroeconomic perception of the importance of taxes, the microeconomic point of view, which monitors changes in tax laws and their impact on business entities, influences the tax base by legal instruments of tax policy (depreciation policy), items affecting the tax base of economic subjects (e.g., non-taxable items). In this chapter, we deal with direct and indirect taxes in Slovakia and their impact on the business sector. The purpose of this chapter is to highlight the trend of tax rates development during 2007–2017 and the factors that significantly affect the level of taxes in Slovakia. Factors that reduce taxes have positive development, but tax rates are constantly a barrier to business area because of tax rates growth.",reviewType:"peer-reviewed",bibtexUrl:"/chapter/bibtex/59364",risUrl:"/chapter/ris/59364",book:{id:"6008",slug:"taxes-and-taxation-trends"},signatures:"Katarina Teplicka",authors:[{id:"218924",title:"Associate Prof.",name:"Katarina",middleName:null,surname:"Teplicka",fullName:"Katarina Teplicka",slug:"katarina-teplicka",email:"katarina.teplicka@tuke.sk",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/218924/images/5928_n.jpg",institution:{name:"Technical University of Košice",institutionURL:null,country:{name:"Slovakia"}}}],sections:[{id:"sec_1",title:"1. Introduction",level:"1"},{id:"sec_2",title:"2. Macroeconomic indicators of taxes",level:"1"},{id:"sec_3",title:"3. Tax rates of direct taxes in Slovakia",level:"1"},{id:"sec_4",title:"4. Limit on tax return",level:"1"},{id:"sec_5",title:"5. Tax indicators in Slovakia",level:"1"},{id:"sec_5_2",title:"5.1. Non-taxable portion of the tax base on wife, husband",level:"2"},{id:"sec_6_2",title:"5.2. Non-taxable portion of the tax base for contributions to supplementary retirement savings (third pillar)",level:"2"},{id:"sec_7_2",title:"5.3. Living wage",level:"2"},{id:"sec_8_2",title:"5.4. Minimum wage",level:"2"},{id:"sec_9_2",title:"5.5. Tax bonus",level:"2"},{id:"sec_11",title:"6. Impact of taxes to business sector",level:"1"},{id:"sec_12",title:"7. Summary",level:"1"}],chapterReferences:[{id:"B1",body:'Burak E, Nemec J. Main factors determining the Slovak tax system performance. Journal of Public Administration and Policy. 2016;9(2):185-197'},{id:"B2",body:'Law 609/2007 consumer tax of electricity, coal, gas'},{id:"B3",body:'Law 106/2004 consumer tax of tobacco'},{id:"B4",body:'Law 222/2004 value added tax'},{id:"B5",body:'Law 354/2011 financial institute'},{id:"B6",body:'Law 431/2002 Z. financial accounting'},{id:"B7",body:'Law 563/2009 administration of taxes'},{id:"B8",body:'Law 582/2004 local income taxes'},{id:"B9",body:'Law 595/2003 income tax'},{id:"B10",body:'Law 601/2003 living wage'},{id:"B11",body:'Law 663/2007 minimum wage'},{id:"B12",body:'Law 98/2004 consumer tax of mineral oil'},{id:"B13",body:'Ližbetinová L, Fábera P, Jambal T, Caha Z. Road tax as an economic tool of the support for the development of multimodal transport in selected EU states. In: International Scientific Conference LOGI 2017. Vol. 134. Nov 8, 2017'},{id:"B14",body:'Maličká L, Šulíková V, Šoltés M. Relationship between fiscal decentralization and economic growth in European Union countries and Slovakia. Ekonomický časopis. 2017;65(9):856-875'},{id:"B15",body:'Stoličná Z, Černička D. Tax systems changes in V4 countries during financial crisis. International Business Information Management Association Conference. May 3–4, 2017. pp. 2546-2551'},{id:"B16",body:'Teplická K, Daubner M. Study of the relation between tax competition and tax burden in European Union member states. Ekonomický časopis, 2013;61(2):172-186'}],footnotes:[],contributors:[{corresp:"yes",contributorFullName:"Katarina Teplicka",address:"katarina.teplicka@tuke.sk",affiliation:'
Department of Management, Faculty of Mining, Ecology, Process Control and Geotechnologies of Kosice, Institute of Earth Resources,, Slovakia
'}],corrections:null},book:{id:"6008",type:"book",title:"Taxes and Taxation Trends",subtitle:null,fullTitle:"Taxes and Taxation Trends",slug:"taxes-and-taxation-trends",publishedDate:"April 20th 2018",bookSignature:"Jolanta Iwin-Garzy?ska",coverURL:"https://cdn.intechopen.com/books/images_new/6008.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",isbn:"978-1-78923-099-4",printIsbn:"978-1-78923-098-7",pdfIsbn:"978-1-83881-267-6",reviewType:"peer-reviewed",numberOfWosCitations:3,isAvailableForWebshopOrdering:!0,editors:[{id:"203547",title:"Prof.",name:"Jolanta",middleName:null,surname:"Iwin-Garzyńska",slug:"jolanta-iwin-garzynska",fullName:"Jolanta Iwin-Garzyńska"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"66"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},chapters:[{id:"58237",type:"chapter",title:"Base of Corporate Income Tax and the EU Concept",slug:"base-of-corporate-income-tax-and-the-eu-concept",totalDownloads:1033,totalCrossrefCites:0,signatures:"Jolanta Iwin-Garzyńska",reviewType:"peer-reviewed",authors:[{id:"203547",title:"Prof.",name:"Jolanta",middleName:null,surname:"Iwin-Garzyńska",fullName:"Jolanta Iwin-Garzyńska",slug:"jolanta-iwin-garzynska"}]},{id:"59384",type:"chapter",title:"International Aspects of Corporate Income Taxes and Associated Distortions",slug:"international-aspects-of-corporate-income-taxes-and-associated-distortions",totalDownloads:1117,totalCrossrefCites:0,signatures:"Liucija Birskyte and Gintare Giriuniene",reviewType:"peer-reviewed",authors:[{id:"219882",title:"Associate Prof.",name:"Liucija",middleName:null,surname:"Birskyte",fullName:"Liucija Birskyte",slug:"liucija-birskyte"},{id:"221132",title:"Dr.",name:"Gintare",middleName:null,surname:"Giriuniene",fullName:"Gintare Giriuniene",slug:"gintare-giriuniene"}]},{id:"59364",type:"chapter",title:"Taxes and Their Impact on the Business Sector in Slovakia",slug:"taxes-and-their-impact-on-the-business-sector-in-slovakia",totalDownloads:1013,totalCrossrefCites:1,signatures:"Katarina Teplicka",reviewType:"peer-reviewed",authors:[{id:"218924",title:"Associate Prof.",name:"Katarina",middleName:null,surname:"Teplicka",fullName:"Katarina Teplicka",slug:"katarina-teplicka"}]},{id:"59430",type:"chapter",title:"Taxation and Economic Growth in a Resource-Rich Country: The Case of Nigeria",slug:"taxation-and-economic-growth-in-a-resource-rich-country-the-case-of-nigeria",totalDownloads:3879,totalCrossrefCites:3,signatures:"Ojijo Odhiambo and Oluwatosin Olushola",reviewType:"peer-reviewed",authors:[{id:"203736",title:"Mr.",name:"Ojijo",middleName:null,surname:"Odhiambo",fullName:"Ojijo Odhiambo",slug:"ojijo-odhiambo"},{id:"206483",title:"Mr.",name:"Oluwatosin",middleName:null,surname:"Olushola",fullName:"Oluwatosin Olushola",slug:"oluwatosin-olushola"}]},{id:"60050",type:"chapter",title:"UK Taxes and Tax Revenues: Composition and Trends",slug:"uk-taxes-and-tax-revenues-composition-and-trends",totalDownloads:1389,totalCrossrefCites:0,signatures:"Zara Ghodsi and Allan Webster",reviewType:"peer-reviewed",authors:[{id:"204043",title:"Prof.",name:"Allan",middleName:null,surname:"Webster",fullName:"Allan Webster",slug:"allan-webster"},{id:"208143",title:"Ms.",name:"Zara",middleName:null,surname:"Ghodsi",fullName:"Zara Ghodsi",slug:"zara-ghodsi"}]},{id:"58324",type:"chapter",title:"How Does a Welfare State achieves Fiscal Sustainability? 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and Supply Management",doi:"10.5772/intechopen.85380",slug:"introductory-chapter-purchasing-and-supply-management",body:'\n
\n\n
There is no doubt that each and every firm have their purchasing department/professionals. Purchasing is the process of acquiring materials, components, and services from another firm. Professional purchasing have addresses following main rights: purchase of the right material, component or service, in the right quantity and quality, at the right place and time [1]. Purchasing gives the foundation of supply management, which tends to have a wider scope of activities [2]. The focus shifts from price to the total cost of ownership.
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Supply management is a five-phase process that starts with the identification of the materials or components required to fulfill the requirement of the enterprise. During this phase, the need is to convert into a statement describing the materials or components required to fulfill the need. It is projected that around 85% of the cost of material is determined during this phase [3, 4]. In sophisticated and multinational firms, supply management professionals and pre-qualified vendors are involved in this phase. The second phase of supply management contains identifying the supplier who will best fulfill the need. The third phase comprises the process of establishing a reasonable and fair price for the material to be purchased. The fourth phase results in an enforceable contract for the purchase that fulfills the requirement of both firms (supplier and buyer). The last phase needs managing the relationship to guarantee quality and delivery time of the material. During this last stage, the supply management firm may work with the supplier in an effort to enhance the efficiency of the supplier with the objective of reducing cost and/or improving quality [2, 5].
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1. Definition of supply management
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There is a long list of definitions on supply management and procurement management (\nFigure 1\n). But the most common definition of supply management is as follows:
\n
Figure 1.
The complex procurement process.
\n\n
\n“The process of obtaining and managing of materials, components or services needed to operate a business or other type of firm. The elements of supply management contain the actual materials/components, budgets, information, and employees. The key purpose of this procedure is to keep costs stable and use resources effectively to increase the efficiency of the business and profits” [6].
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Following are the basic responsibilities of an effective purchasing and supply management team.
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2. Reducing cost
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Purchasing has a direct impact on firms’ profitability and expenditure. The procurement professional task is to reduce the cost of product, material or service through supplier relationship development and negotiations [7]. In addition, procurement professionals have a responsibility to create value for the firm in terms of cost reduction and improving the quality of the item. Generally, the material cost is two and a half times the payroll costs [1, 8]. It is the key reason firms see great value in procurement professionals who are able to increase the quality of products and savings.
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3. Negotiation
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Negotiation plays a vital role in the reduction of cost and enhancing the quality of the item. Procurement professionals are tasked with negotiating terms with suppliers that benefit to the firm in terms of delivery time, quality of materials, and reduction in price/cost of material [1, 9, 10]. Undeniably, this not only affects the sales and revenue of firms but also create a competitive advantage. The successful supply management professionals’ team is relying on the ability to foresee long-term business relationship and strong negotiation skills.
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4. Developing supplier relationships
\n
Usually firms require suppliers on an ongoing basis due to one-off purchases is very costly and as a result, it is crucial to building a long-term relationship with suppliers. A supplier–buyer good relationship can create flexibility in the supply chain [6, 11]. In addition, by working with the supplier on a long-term basis, firms may increase competitive edge, higher cost savings, and fine-tune schedules. Further, buyer–supplier relationships benefit both and build trust and collaboration, which allowing both parties to succeed [12].
\n
\n
\n
5. Mitigating risk
\n
Purchasing and management have a responsibility to understand the potential risks and develop innovative strategies to manage them. An effective risk mitigation strategy may protect firms from a big loss [1, 13]. Potential risks contain transparency and fraud, counterfeit materials and intellectual property. Further, supply management professionals need to have a plan B in place if supplies are delayed from the suppliers’ side or due to changes in schedule.
\n
\n\n',keywords:null,chapterPDFUrl:"https://cdn.intechopen.com/pdfs/66342.pdf",chapterXML:"https://mts.intechopen.com/source/xml/66342.xml",downloadPdfUrl:"/chapter/pdf-download/66342",previewPdfUrl:"/chapter/pdf-preview/66342",totalDownloads:2183,totalViews:0,totalCrossrefCites:4,dateSubmitted:"February 19th 2019",dateReviewed:"February 22nd 2019",datePrePublished:"March 25th 2019",datePublished:"May 13th 2020",dateFinished:"March 25th 2019",readingETA:"0",abstract:null,reviewType:"peer-reviewed",bibtexUrl:"/chapter/bibtex/66342",risUrl:"/chapter/ris/66342",signatures:"Syed Abdul Rehman Khan and Zhang Yu",book:{id:"8924",type:"book",title:"Modern Perspectives in Business Applications",subtitle:null,fullTitle:"Modern Perspectives in Business Applications",slug:"modern-perspectives-in-business-applications",publishedDate:"May 13th 2020",bookSignature:"Syed Abdul Rehman Khan and Selay Ilgaz Sümer",coverURL:"https://cdn.intechopen.com/books/images_new/8924.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",isbn:"978-1-78984-973-8",printIsbn:"978-1-78984-972-1",pdfIsbn:"978-1-78985-225-7",isAvailableForWebshopOrdering:!0,editors:[{id:"254664",title:"Prof.",name:"Syed Abdul Rehman",middleName:null,surname:"Khan",slug:"syed-abdul-rehman-khan",fullName:"Syed Abdul Rehman Khan"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}},authors:[{id:"254664",title:"Prof.",name:"Syed Abdul Rehman",middleName:null,surname:"Khan",fullName:"Syed Abdul Rehman Khan",slug:"syed-abdul-rehman-khan",email:"sarehman_cscp@yahoo.com",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/254664/images/system/254664.jpg",institution:{name:"Nanjing University",institutionURL:null,country:{name:"China"}}}],sections:[{id:"sec_1",title:"",level:"1"},{id:"sec_2",title:"1. Definition of supply management",level:"1"},{id:"sec_3",title:"2. Reducing cost",level:"1"},{id:"sec_4",title:"3. Negotiation",level:"1"},{id:"sec_5",title:"4. Developing supplier relationships",level:"1"},{id:"sec_6",title:"5. Mitigating risk",level:"1"}],chapterReferences:[{id:"B1",body:'\nKhan SAR, Dong Q. Impact of green supply chain management practices on firms’ performance: An empirical study from the perspective of Pakistan. Environmental Science and Pollution Research. 2017;24:16829-16844. DOI: 10.1007/s11356-017-9172-5\n'},{id:"B2",body:'\nKhan SAR, Qianli D, SongBo W, Zaman K, Zhang Y. Environmental logistics performance indicators affecting per capita income and sectoral growth: Evidence from a panel of selected global ranked logistics countries. Environmental Science and Pollution Research. 2017;24(2):1518-1531. DOI: 10.1007/s11356-016-7916-2\n'},{id:"B3",body:'\nKhan SAR. Introductory chapter: Introduction of green supply chain management [online first]. IntechOpen. 2018. DOI: 10.5772/intechopen.81088. Available from: https://www.intechopen.com/online-first/introductory-chapter-introduction-of-green-supply-chain-management\n\n'},{id:"B4",body:'\nSarkis J, Zhu Q, Lai K. An organizational theoretic review of green supply chain management literature. International Journal of Production Economics. 2011;130(1):1-15\n'},{id:"B5",body:'\nAndic E, Yurt O, Baltacioglu T. Green supply chains: Efforts and potential applications for the Turkish market. Resources, Conservation and Recycling. 2012;58:50-68\n'},{id:"B6",body:'\nKhan SAR, Dong QL, Yu Z. Research on the measuring performance of green supply chain management: In the perspective of China. International Journal of Engineering Research in Africa. 2016;27:167-178. DOI: 10.4028/www.scientific.net/JERA.27.167\n'},{id:"B7",body:'\nLuthra S, Garg D, Haleem A. The impacts of critical success factors for implementing green supply chain management towards sustainability: An empirical investigation of Indian automobile industry. Journal of Cleaner Production. 2016;121:142-158\n'},{id:"B8",body:'\nGunasekaran A, Spalanzani A. Sustainability of manufacturing and services: Investigations for research and applications. International Journal of Production Economics. 2012;140(1):35-47\n'},{id:"B9",body:'\nMangla S, Madaan J, Chan FT. Analysis of flexible decision strategies for sustainability-focused green product recovery system. International Journal of Production Research. 2013;51(11):3428-3442\n'},{id:"B10",body:'\nOmkareshwar M. Green marketing initiatives by corporate world: A study. Advances in Management. 2013;6(3):20-26\n'},{id:"B11",body:'\nZhu Q, Sarkis J, Lai KH. Green supply chain management: Pressures, practices, and performance within the Chinese automobile industry. Journal of Cleaner Production. 2007;15(11):1041-1052\n'},{id:"B12",body:'\nAwasthi A, Kannan G. Green supplier development program selection using NGT and VIKOPR under fuzzy environment. Computers and Industrial Engineering. 2016;91:100-108\n'},{id:"B13",body:'\nHu AH, Hsu CW. Critical factors for implementing green supply chain management practice: An empirical study of electrical and electronics industries in Taiwan. Management Research Review. 2010;33(6):586-608\n'}],footnotes:[],contributors:[{corresp:"yes",contributorFullName:"Syed Abdul Rehman Khan",address:"sarehman_cscp@yahoo.com",affiliation:'
School of Economics and Management, Tsinghua University, China
School of Economics and Management, Chang’an University, China
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In 2001 he was selected for Associate Member of National Academy of Sciences of Azerbaijan in the field of Information Technologies. He is a member of Editorial Board of the journals Applied Mathematics (Scientific Research, USA) and Resent Patents on Electrical Engineering (Bentham Science Publisher, USA), Applied and Computational Mathematics (Azerbaijan).",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/23032/images/1564_n.jpg",totalCites:0,totalChapterViews:"0",outsideEditionCount:0,totalAuthoredChapters:"1",totalEditedBooks:"1",personalWebsiteURL:null,twitterURL:null,linkedinURL:null,institution:null},booksEdited:[{id:"97",type:"book",slug:"cellular-networks-positioning-performance-analysis-reliability",title:"Cellular Networks",subtitle:"Positioning, Performance Analysis, Reliability",coverURL:"https://cdn.intechopen.com/books/images_new/97.jpg",abstract:"Wireless cellular networks are an integral part of modern telecommunication systems. Today it is hard to imagine our life without the use of such networks. Nevertheless, the development, implementation and operation of these networks require engineers and scientists to address a number of interrelated problems. Among them are the problem of choosing the proper geometric shape and dimensions of cells based on geographical location, finding the optimal location of cell base station, selection the scheme dividing the total net bandwidth between its cells, organization of the handover of a call between cells, information security and network reliability, and many others. The book focuses on three types of problems from the above list - Positioning, Performance Analysis and Reliability. It contains three sections. The Section 1 is devoted to problems of Positioning and contains five chapters. The Section 2 contains eight Chapters which are devoted to quality of service (QoS) metrics analysis of wireless cellular networks. 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His studies in robotics lead him not only to a PhD degree but also inspired him to co-found and build the International Journal of Advanced Robotic Systems - world's first Open Access journal in the field of robotics.",institutionString:null,institution:{name:"TU Wien",country:{name:"Austria"}}},{id:"441",title:"Ph.D.",name:"Jaekyu",middleName:null,surname:"Park",slug:"jaekyu-park",fullName:"Jaekyu Park",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/441/images/1881_n.jpg",biography:null,institutionString:null,institution:{name:"LG Corporation (South Korea)",country:{name:"Korea, South"}}},{id:"465",title:"Dr",name:"Christian",middleName:null,surname:"Martens",slug:"christian-martens",fullName:"Christian Martens",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"479",title:"Dr.",name:"Valentina",middleName:null,surname:"Colla",slug:"valentina-colla",fullName:"Valentina Colla",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/479/images/358_n.jpg",biography:null,institutionString:null,institution:{name:"Sant'Anna School of Advanced Studies",country:{name:"Italy"}}},{id:"494",title:"PhD",name:"Loris",middleName:null,surname:"Nanni",slug:"loris-nanni",fullName:"Loris Nanni",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/494/images/system/494.jpg",biography:"Loris Nanni received his Master Degree cum laude on June-2002 from the University of Bologna, and the April 26th 2006 he received his Ph.D. in Computer Engineering at DEIS, University of Bologna. On September, 29th 2006 he has won a post PhD fellowship from the university of Bologna (from October 2006 to October 2008), at the competitive examination he was ranked first in the industrial engineering area. He extensively served as referee for several international journals. He is author/coauthor of more than 100 research papers. He has been involved in some projects supported by MURST and European Community. 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Delac received his B.Sc.E.E. degree in 2003 and is currentlypursuing a Ph.D. degree at the University of Zagreb, Faculty of Electrical Engineering andComputing. His current research interests are digital image analysis, pattern recognition andbiometrics.",institutionString:null,institution:{name:"University of Zagreb",country:{name:"Croatia"}}},{id:"557",title:"Dr.",name:"Andon",middleName:"Venelinov",surname:"Topalov",slug:"andon-topalov",fullName:"Andon Topalov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/557/images/1927_n.jpg",biography:"Dr. Andon V. Topalov received the MSc degree in Control Engineering from the Faculty of Information Systems, Technologies, and Automation at Moscow State University of Civil Engineering (MGGU) in 1979. He then received his PhD degree in Control Engineering from the Department of Automation and Remote Control at Moscow State Mining University (MGSU), Moscow, in 1984. From 1985 to 1986, he was a Research Fellow in the Research Institute for Electronic Equipment, ZZU AD, Plovdiv, Bulgaria. In 1986, he joined the Department of Control Systems, Technical University of Sofia at the Plovdiv campus, where he is presently a Full Professor. He has held long-term visiting Professor/Scholar positions at various institutions in South Korea, Turkey, Mexico, Greece, Belgium, UK, and Germany. And he has coauthored one book and authored or coauthored more than 80 research papers in conference proceedings and journals. His current research interests are in the fields of intelligent control and robotics.",institutionString:null,institution:{name:"Technical University of Sofia",country:{name:"Bulgaria"}}},{id:"585",title:"Prof.",name:"Munir",middleName:null,surname:"Merdan",slug:"munir-merdan",fullName:"Munir Merdan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/585/images/system/585.jpg",biography:"Munir Merdan received the M.Sc. degree in mechanical engineering from the Technical University of Sarajevo, Bosnia and Herzegovina, in 2001, and the Ph.D. degree in electrical engineering from the Vienna University of Technology, Vienna, Austria, in 2009.Since 2005, he has been at the Automation and Control Institute, Vienna University of Technology, where he is currently a Senior Researcher. His research interests include the application of agent technology for achieving agile control in the manufacturing environment.",institutionString:null,institution:null},{id:"605",title:"Prof",name:"Dil",middleName:null,surname:"Hussain",slug:"dil-hussain",fullName:"Dil Hussain",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/605/images/system/605.jpg",biography:"Dr. Dil Muhammad Akbar Hussain is a professor of Electronics Engineering & Computer Science at the Department of Energy Technology, Aalborg University Denmark. Professor Akbar has a Master degree in Digital Electronics from Govt. College University, Lahore Pakistan and a P-hD degree in Control Engineering from the School of Engineering and Applied Sciences, University of Sussex United Kingdom. Aalborg University has Two Satellite Campuses, one in Copenhagen (Aalborg University Copenhagen) and the other in Esbjerg (Aalborg University Esbjerg).\n· He is a member of prestigious IEEE (Institute of Electrical and Electronics Engineers), and IAENG (International Association of Engineers) organizations. \n· He is the chief Editor of the Journal of Software Engineering.\n· He is the member of the Editorial Board of International Journal of Computer Science and Software Technology (IJCSST) and International Journal of Computer Engineering and Information Technology. \n· He is also the Editor of Communication in Computer and Information Science CCIS-20 by Springer.\n· Reviewer For Many Conferences\nHe is the lead person in making collaboration agreements between Aalborg University and many universities of Pakistan, for which the MOU’s (Memorandum of Understanding) have been signed.\nProfessor Akbar is working in Academia since 1990, he started his career as a Lab demonstrator/TA at the University of Sussex. After finishing his P. hD degree in 1992, he served in the Industry as a Scientific Officer and continued his academic career as a visiting scholar for a number of educational institutions. In 1996 he joined National University of Science & Technology Pakistan (NUST) as an Associate Professor; NUST is one of the top few universities in Pakistan. In 1999 he joined an International Company Lineo Inc, Canada as Manager Compiler Group, where he headed the group for developing Compiler Tool Chain and Porting of Operating Systems for the BLACKfin processor. The processor development was a joint venture by Intel and Analog Devices. In 2002 Lineo Inc., was taken over by another company, so he joined Aalborg University Denmark as an Assistant Professor.\nProfessor Akbar has truly a multi-disciplined career and he continued his legacy and making progress in many areas of his interests both in teaching and research. 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These environmental adversities generally induce the accumulation of reactive oxygen species (ROS), which can cause severe oxidative damage to plants. ROS are toxic molecules found in various subcellular compartments. The equilibrium between the production and detoxification of ROS is sustained by enzymatic and nonenzymatic antioxidants. Due to advances in molecular approaches during the last decades, nowadays it is possible to develop economically important transgenic crops that have increased tolerance to stresses. This chapter discusses the oxidative stress and damage to plants. In addition, it reports the involvement of antioxidant enzymes in the tolerance of plants to various stresses.",book:{id:"5066",slug:"abiotic-and-biotic-stress-in-plants-recent-advances-and-future-perspectives",title:"Abiotic and Biotic Stress in Plants",fullTitle:"Abiotic and Biotic Stress in Plants - Recent Advances and Future Perspectives"},signatures:"Andréia Caverzan, Alice Casassola and Sandra Patussi Brammer",authors:[{id:"176303",title:"Dr.",name:"Alice",middleName:null,surname:"Casassola",slug:"alice-casassola",fullName:"Alice Casassola"},{id:"176409",title:"Dr.",name:"Andréia",middleName:null,surname:"Caverzan",slug:"andreia-caverzan",fullName:"Andréia Caverzan"},{id:"176410",title:"Dr.",name:"Sandra",middleName:null,surname:"Patussi Brammer",slug:"sandra-patussi-brammer",fullName:"Sandra Patussi Brammer"}]},{id:"49289",doi:"10.5772/61442",title:"Abiotic and Biotic Elicitors–Role in Secondary Metabolites Production through In Vitro Culture of Medicinal Plants",slug:"abiotic-and-biotic-elicitors-role-in-secondary-metabolites-production-through-in-vitro-culture-of-me",totalDownloads:6998,totalCrossrefCites:40,totalDimensionsCites:106,abstract:"Plant secondary metabolites are having the great application in human health and nutritional aspect. Plant cell and organ culture systems are feasible option for the production of secondary metabolites that are of commercial importance in pharmaceuticals, food additives, flavors, and other industrial materials. The stress, including various elicitors or signal molecules, often induces the secondary metabolite production in the plant tissue culture system. The recent developments in elicitation of plant tissue culture have opened a new avenue for the production of secondary metabolite compounds. Secondary metabolite synthesis and accumulation in cell and organ cultures can be triggered by the application of elicitors to the culture medium. Elicitors are the chemical compounds from abiotic and biotic sources that can stimulate stress responses in plants, leading to the enhanced synthesis and accumulation of secondary metabolites or the induction of novel secondary metabolites. Elicitor type, dose, and treatment schedule are major factors determining the effects on the secondary metabolite production. The number of parameters, such as elicitor concentrations, duration of exposure, cell line, nutrient composition, and age or stage of the culture, is also important factors influencing the successful production of biomass and secondary metabolite accumulation. This chapter reviews the various abiotic and biotic elicitors applied to cultural system and their stimulating effects on the accumulation of secondary metabolites.",book:{id:"5066",slug:"abiotic-and-biotic-stress-in-plants-recent-advances-and-future-perspectives",title:"Abiotic and Biotic Stress in Plants",fullTitle:"Abiotic and Biotic Stress in Plants - Recent Advances and Future Perspectives"},signatures:"Poornananda M. Naik and Jameel M. Al–Khayri",authors:[{id:"176282",title:"Prof.",name:"Jameel M.",middleName:null,surname:"Al-Khayri",slug:"jameel-m.-al-khayri",fullName:"Jameel M. 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The uses of medicinal plants for human and animal treatments are practiced from time immemorial. Stream/riverbanks, cultivated lands, disturbed sites, bushlands, forested areas and their margins, woodlands, grasslands, and home gardens are major habitats of medicinal plants. Generally, medicinal plants used for traditional medicine play a significant role in the healthcare of the majority of the people in Ethiopia. The major threats to medicinal plants are habitat destruction, urbanization, agricultural expansion, investment, road construction, and deforestation. Because of these, medicinal plants are being declined and lost with their habitats. Community- and research-based conservation mechanisms could be an appropriate approach for mitigating the problems pertinent to the loss of medicinal plants and their habitats and for documenting medicinal plants. Chromatography; electrophoretic, macroscopic, and microscopic techniques; and pharmaceutical practice are mainly used for quality control of herbal medicines.",book:{id:"8502",slug:"plant-science-structure-anatomy-and-physiology-in-plants-cultured-in-vivo-and-in-vitro",title:"Plant Science",fullTitle:"Plant Science - Structure, Anatomy and Physiology in Plants Cultured in Vivo and in Vitro"},signatures:"Admasu Moges and Yohannes Moges",authors:[{id:"249746",title:"Ph.D.",name:"Admasu",middleName:null,surname:"Moges",slug:"admasu-moges",fullName:"Admasu Moges"},{id:"297761",title:"MSc.",name:"Yohannes",middleName:null,surname:"Moges",slug:"yohannes-moges",fullName:"Yohannes Moges"}]},{id:"63148",title:"Domestic Livestock and Its Alleged Role in Climate Change",slug:"domestic-livestock-and-its-alleged-role-in-climate-change",totalDownloads:15897,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"It is very old wisdom that climate dictates farm management strategies. In recent years, however, we are increasingly confronted with claims that agriculture, livestock husbandry, and even food consumption habits are forcing the climate to change. We subjected this worrisome concern expressed by public institutions, the media, policy makers, and even scientists to a rigorous review, cross-checking critical coherence and (in)compatibilities within and between published scientific papers. Our key conclusion is there is no need for anthropogenic emissions of greenhouse gases (GHGs), and even less so for livestock-born emissions, to explain climate change. Climate has always been changing, and even the present warming is most likely driven by natural factors. The warming potential of anthropogenic GHG emissions has been exaggerated, and the beneficial impacts of manmade CO2 emissions for nature, agriculture, and global food security have been systematically suppressed, ignored, or at least downplayed by the IPCC (Intergovernmental Panel on Climate Change) and other UN (United Nations) agencies. Furthermore, we expose important methodological deficiencies in IPCC and FAO (Food Agriculture Organization) instructions and applications for the quantification of the manmade part of non-CO2-GHG emissions from agro-ecosystems. However, so far, these fatal errors inexorably propagated through scientific literature. Finally, we could not find a clear domestic livestock fingerprint, neither in the geographical methane distribution nor in the historical evolution of mean atmospheric methane concentration. In conclusion, everybody is free to choose a vegetarian or vegan lifestyle, but there is no scientific basis, whatsoever, for claiming this decision could contribute to save the planet’s climate.",book:{id:"7491",slug:"forage-groups",title:"Forage Groups",fullTitle:"Forage Groups"},signatures:"Albrecht Glatzle",authors:[{id:"252990",title:"Dr.",name:"Albrecht",middleName:null,surname:"Glatzle",slug:"albrecht-glatzle",fullName:"Albrecht Glatzle"}]},{id:"66714",title:"Biotic and Abiotic Stresses in Plants",slug:"biotic-and-abiotic-stresses-in-plants",totalDownloads:5808,totalCrossrefCites:54,totalDimensionsCites:96,abstract:"Plants are subjected to a wide range of environmental stresses which reduces and limits the productivity of agricultural crops. Two types of environmental stresses are encountered to plants which can be categorized as (1) Abiotic stress and (2) Biotic stress. The abiotic stress causes the loss of major crop plants worldwide and includes radiation, salinity, floods, drought, extremes in temperature, heavy metals, etc. On the other hand, attacks by various pathogens such as fungi, bacteria, oomycetes, nematodes and herbivores are included in biotic stresses. As plants are sessile in nature, they have no choice to escape from these environmental cues. Plants have developed various mechanisms in order to overcome these threats of biotic and abiotic stresses. They sense the external stress environment, get stimulated and then generate appropriate cellular responses. They do this by stimuli received from the sensors located on the cell surface or cytoplasm and transferred to the transcriptional machinery situated in the nucleus, with the help of various signal transduction pathways. This leads to differential transcriptional changes making the plant tolerant against the stress. The signaling pathways act as a connecting link and play an important role between sensing the stress environment and generating an appropriate biochemical and physiological response.",book:{id:"8015",slug:"abiotic-and-biotic-stress-in-plants",title:"Abiotic and Biotic Stress in Plants",fullTitle:"Abiotic and Biotic Stress in Plants"},signatures:"Audil Gull, Ajaz Ahmad Lone and Noor Ul Islam Wani",authors:null},{id:"62573",title:"Introductory Chapter: Terpenes and Terpenoids",slug:"introductory-chapter-terpenes-and-terpenoids",totalDownloads:7556,totalCrossrefCites:27,totalDimensionsCites:51,abstract:null,book:{id:"6530",slug:"terpenes-and-terpenoids",title:"Terpenes and Terpenoids",fullTitle:"Terpenes and Terpenoids"},signatures:"Shagufta Perveen",authors:[{id:"192992",title:"Prof.",name:"Shagufta",middleName:null,surname:"Perveen",slug:"shagufta-perveen",fullName:"Shagufta Perveen"},{id:"192994",title:"Dr.",name:"Areej",middleName:null,surname:"Al-Taweel",slug:"areej-al-taweel",fullName:"Areej Al-Taweel"}]},{id:"62876",title:"Introduction to Phytochemicals: Secondary Metabolites from Plants with Active Principles for Pharmacological Importance",slug:"introduction-to-phytochemicals-secondary-metabolites-from-plants-with-active-principles-for-pharmaco",totalDownloads:5802,totalCrossrefCites:10,totalDimensionsCites:25,abstract:"Phytochemicals are substances produced mainly by plants, and these substances have biological activity. In the pharmaceutical industry, plants represent the main source to obtain various active ingredients. They exhibit pharmacological effects applicable to the treatment of bacterial and fungal infections and also chronic-degenerative diseases such as diabetes and cancer. However, the next step in science is to find new ways to obtain it. In this chapter, we discuss about the main groups of phytochemicals, in addition to presenting two case studies. One of the most important secondary metabolites is currently Taxol, which is a natural compound of the taxoid family and is also known for its antitumor activity against cancer located in breasts, lungs, and prostate and is also effective with Kaposi’s sarcoma. Our case studies will be about Taxol, extracted from an unexplored plant species, and the production of Taxol by its endophytic fungi.",book:{id:"6794",slug:"phytochemicals-source-of-antioxidants-and-role-in-disease-prevention",title:"Phytochemicals",fullTitle:"Phytochemicals - Source of Antioxidants and Role in Disease Prevention"},signatures:"Nadia Mendoza and Eleazar M. Escamilla Silva",authors:[{id:"51406",title:"Dr.",name:"Eleazar",middleName:"Máximo",surname:"Escamilla Silva",slug:"eleazar-escamilla-silva",fullName:"Eleazar Escamilla Silva"},{id:"243304",title:"Ph.D. Student",name:"Nadia",middleName:null,surname:"Mendoza",slug:"nadia-mendoza",fullName:"Nadia Mendoza"}]}],onlineFirstChaptersFilter:{topicId:"41",limit:6,offset:0},onlineFirstChaptersCollection:[{id:"81798",title:"Protein Metabolism in Plants to Survive against Abiotic Stress",slug:"protein-metabolism-in-plants-to-survive-against-abiotic-stress",totalDownloads:29,totalDimensionsCites:0,doi:"10.5772/intechopen.102995",abstract:"Plants are frequently subjected to several abiotic environmental stresses under natural conditions causing profound impacts on agricultural yield and quality. Plants can themselves develop a wide variety of efficient mechanisms to respond environmental challenges. Tolerance and acclimation of plants are always related to significant changes in protein, cellular localization, posttranscription, and posttranslational modifications. Protein response pathways as well as pathways unique to a given stress condition shared by plants under different stressed environment are discussed in this chapter. The various signaling of protein such as fluctuation, overexpression, and silencing of the protein gene are observed to be modulated in drought-tolerant plants. Similarly, gene expression, RNA processing, and metabolic process take place to cope with drought conditions. For adaption in water-submerged conditions, plants undergo reactive oxygen species (ROS), cell wall modification, proteolysis, and post-recovery protein metabolism. Heat shock protein and protein and lipid contents vary and play pivotal role in resisting low and high temperatures. In a nutshell, this paper provides an overview of several modification, synthesis, degradation, and metabolism of protein in plants to cope with and revive again to normal growing conditions against abiotic stress, emphasizing drought, submerged, extreme cold, and heat temperatures.",book:{id:"10905",title:"Plant Defense Mechanisms",coverURL:"https://cdn.intechopen.com/books/images_new/10905.jpg"},signatures:"Bharti Thapa and Abhisek Shrestha"},{id:"80923",title:"Salt Stress Tolerance in Rice and Wheat: Physiological and Molecular Mechanism",slug:"salt-stress-tolerance-in-rice-and-wheat-physiological-and-molecular-mechanism",totalDownloads:70,totalDimensionsCites:0,doi:"10.5772/intechopen.101529",abstract:"Salinity is a major obstacle to global grain crop production, especially rice and wheat. The identification and improvement of salt-tolerant rice and wheat depending upon the genetic diversity and salt stress response could be a promising solution to deal with soil salinity and the increasing food demands. Plant responses to salt stress occur at the organismic, cellular, and molecular levels and the salt stress tolerance in those crop plant involving (1) regulation of ionic homeostasis, (2) maintenance of osmotic potential, (3) ROS scavenging and antioxidant enzymes activity, and (4) plant hormonal regulation. In this chapter, we summarize the recent research progress on these four aspects of plant morpho-physiological and molecular response, with particular attention to ionic, osmolytic, enzymatic, hormonal and gene expression regulation in rice and wheat plants. Moreover, epigenetic diversity could emerge as novel of phenotypic variations to enhance plant adaptation to an adverse environmental conditions and develop stable stress-resilient crops. The information summarized here will be useful for accelerating the breeding of salt-tolerant rice. This information may help in studies to reveal the mechanism of plant salt tolerance, screen high efficiency and quality salt tolerance in crops.",book:{id:"10905",title:"Plant Defense Mechanisms",coverURL:"https://cdn.intechopen.com/books/images_new/10905.jpg"},signatures:"Mohammad Hasanuzzaman"},{id:"80091",title:"Molecular Defense Mechanisms in Plants to Tolerate Toxic Action of Heavy Metal Environmental Pollution",slug:"molecular-defense-mechanisms-in-plants-to-tolerate-toxic-action-of-heavy-metal-environmental-polluti",totalDownloads:26,totalDimensionsCites:0,doi:"10.5772/intechopen.102330",abstract:"Toxic action of heavy metals on plants growing in contaminated soils intensified the research on detoxification and sequestering mechanisms existing in plants to understand and manipulate defense mechanisms that confer tolerance against metal ions. Increased biosynthesis of plant biomolecules to confer tolerance during toxic action of heavy metals is an intrinsic ability of plants. Induced formation of low-molecular weight amino acids, peptides or proteines as chelators such as proline (Pro), glutathione (GSH), phytochelatins (PCs) or metallothioneins (MTs) under heavy metal stress enhances metal binding and detoxification capability of plants. In addition, proline and GSH related enzymes such as GSH reductase, GSH peroxidases and glutathione S-transferases are also key components of the antioxidant defense system in the cells to scavenge reactive oxygen species (ROS). Protective action of oxidized fatty acids oxylipins at toxic levels of heavy metals is considered to activate detoxification processes as signaling molecules.",book:{id:"10905",title:"Plant Defense Mechanisms",coverURL:"https://cdn.intechopen.com/books/images_new/10905.jpg"},signatures:"Istvan Jablonkai"},{id:"80723",title:"Intra-Annual Variation in Leaf Anatomical Traits of an Overwintering Shrub of High Elevations of Himalaya",slug:"intra-annual-variation-in-leaf-anatomical-traits-of-an-overwintering-shrub-of-high-elevations-of-him",totalDownloads:34,totalDimensionsCites:0,doi:"10.5772/intechopen.102016",abstract:"Trait variability in response to seasonal variations can be hypothesised as an advantageous strategy for overwintering shrubs. This hypothesis was tested by elucidating patterns of trait variation in an evergreen alpine shrub, Rhododendron anthopogon D. Don. The study site was established at Rohtang (3990 m a.s.l.) in western Himalaya. Its leaves were sampled at 10 time points spanning a period of 1 year (beginning from 22-August-2017 to 14-August-2018) for estimating anatomical traits using light and scanning electron microscopy. The data were analysed using one-way analysis of variance, and the trait-temperature relationships were analysed using linear regression. The results indicated a lower variability in the anatomical traits. A few traits (e.g. cuticle thickness and epidermal scales) were found to be significantly correlated with temperature (p < 0.05). Our analysis revealed increase in cuticle thickness and a decrease in epidermal scales (size) during low-temperature conditions. The lesser variability found in anatomical traits of overwintering shrub could be explained as ‘evolutionary gained adaptive traits’.",book:{id:"10905",title:"Plant Defense Mechanisms",coverURL:"https://cdn.intechopen.com/books/images_new/10905.jpg"},signatures:"Nikita Rathore, Dinesh Thakur, Nang Elennie Hopak and Amit Chawla"},{id:"80587",title:"Morpho-Anatomical Adaptation against Salinity",slug:"morpho-anatomical-adaptation-against-salinity",totalDownloads:73,totalDimensionsCites:0,doi:"10.5772/intechopen.101681",abstract:"Plants tolerant of NaCl, implement several adjustments to acclimate to salt stress, such as biochemical, physiological, and morphological modifications. Besides, plants also adjust to saline circumstances by altering their anatomical structure of roots, leaves, and morphological modifications. The leaf and roots are among the essential plant organs and are involved in the transport of water and minerals used for photosynthesis. From a plant physiology perspective, water use efficiency in the quantity of CO2 fixed in photosynthesis compared to the leaf anatomy. In this review, we provide a comparative account of the morphology of the leaf and root under normal and salt stress circumstances. There is little information on the ultrastructure changes elicited in response to salt stress. The analysis expands our knowledge of how salt may impact the leaves and root anatomy.",book:{id:"10905",title:"Plant Defense Mechanisms",coverURL:"https://cdn.intechopen.com/books/images_new/10905.jpg"},signatures:"Smita Srivastava"},{id:"80201",title:"Nutrients Deficit and Water Stress in Plants: New Concept Solutions Using Olive Solid Waste",slug:"nutrients-deficit-and-water-stress-in-plants-new-concept-solutions-using-olive-solid-waste",totalDownloads:81,totalDimensionsCites:0,doi:"10.5772/intechopen.101523",abstract:"Great efforts were deployed by researchers to mobilize water resources while is becoming rarer and to control with efficiency the water besides nutrient needs for the plant. Autonomous water and nutritional anti-stress device for plants (AWANASD) based on the recovery of rainwater patented by Medhioub et al. fits into this general framework. Scientific efforts were also dedicated to preserve the environment and minimize energy consumption through using agricultural waste materials in different fields. This chapter provides a new concept based on the use of the olive solid waste in AWANASD as water storage and nutrient elements for plants giving rise to the new system called AWANASD-OSW.",book:{id:"10905",title:"Plant Defense Mechanisms",coverURL:"https://cdn.intechopen.com/books/images_new/10905.jpg"},signatures:"Samir Medhioub, Slah Bouraoui, Ali Ellouze and Hassen Sabeur"}],onlineFirstChaptersTotal:9},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:89,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:104,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:31,numberOfPublishedChapters:314,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:11,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:141,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:129,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:113,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:105,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:18,numberOfOpenTopics:2,numberOfUpcomingTopics:1,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:5,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:14,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}},{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}}]},series:{item:{id:"24",title:"Sustainable Development",doi:"10.5772/intechopen.100361",issn:null,scope:"
\r\n\tTransforming our World: the 2030 Agenda for Sustainable Development endorsed by United Nations and 193 Member States, came into effect on Jan 1, 2016, to guide decision making and actions to the year 2030 and beyond. Central to this Agenda are 17 Goals, 169 associated targets and over 230 indicators that are reviewed annually. The vision envisaged in the implementation of the SDGs is centered on the five Ps: People, Planet, Prosperity, Peace and Partnership. This call for renewed focused efforts ensure we have a safe and healthy planet for current and future generations.
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\r\n\tThis Series focuses on covering research and applied research involving the five Ps through the following topics:
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\r\n\t1. Sustainable Economy and Fair Society that relates to SDG 1 on No Poverty, SDG 2 on Zero Hunger, SDG 8 on Decent Work and Economic Growth, SDG 10 on Reduced Inequalities, SDG 12 on Responsible Consumption and Production, and SDG 17 Partnership for the Goals
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\r\n\t2. Health and Wellbeing focusing on SDG 3 on Good Health and Wellbeing and SDG 6 on Clean Water and Sanitation
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\r\n\t3. Inclusivity and Social Equality involving SDG 4 on Quality Education, SDG 5 on Gender Equality, and SDG 16 on Peace, Justice and Strong Institutions
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\r\n\t4. Climate Change and Environmental Sustainability comprising SDG 13 on Climate Action, SDG 14 on Life Below Water, and SDG 15 on Life on Land
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\r\n\t5. Urban Planning and Environmental Management embracing SDG 7 on Affordable Clean Energy, SDG 9 on Industry, Innovation and Infrastructure, and SDG 11 on Sustainable Cities and Communities.
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\r\n\tThe series also seeks to support the use of cross cutting SDGs, as many of the goals listed above, targets and indicators are all interconnected to impact our lives and the decisions we make on a daily basis, making them impossible to tie to a single topic.
",coverUrl:"https://cdn.intechopen.com/series/covers/24.jpg",latestPublicationDate:"June 23rd, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:0,editor:{id:"262440",title:"Prof.",name:"Usha",middleName:null,surname:"Iyer-Raniga",slug:"usha-iyer-raniga",fullName:"Usha Iyer-Raniga",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRYSXQA4/Profile_Picture_2022-02-28T13:55:36.jpeg",biography:"Usha Iyer-Raniga is a professor in the School of Property and Construction Management at RMIT University. Usha co-leads the One Planet Network’s Sustainable Buildings and Construction Programme (SBC), a United Nations 10 Year Framework of Programmes on Sustainable Consumption and Production (UN 10FYP SCP) aligned with Sustainable Development Goal 12. The work also directly impacts SDG 11 on Sustainable Cities and Communities. She completed her undergraduate degree as an architect before obtaining her Masters degree from Canada and her Doctorate in Australia. Usha has been a keynote speaker as well as an invited speaker at national and international conferences, seminars and workshops. Her teaching experience includes teaching in Asian countries. She has advised Austrade, APEC, national, state and local governments. She serves as a reviewer and a member of the scientific committee for national and international refereed journals and refereed conferences. She is on the editorial board for refereed journals and has worked on Special Issues. Usha has served and continues to serve on the Boards of several not-for-profit organisations and she has also served as panel judge for a number of awards including the Premiers Sustainability Award in Victoria and the International Green Gown Awards. Usha has published over 100 publications, including research and consulting reports. Her publications cover a wide range of scientific and technical research publications that include edited books, book chapters, refereed journals, refereed conference papers and reports for local, state and federal government clients. She has also produced podcasts for various organisations and participated in media interviews. She has received state, national and international funding worth over USD $25 million. Usha has been awarded the Quarterly Franklin Membership by London Journals Press (UK). Her biography has been included in the Marquis Who's Who in the World® 2018, 2016 (33rd Edition), along with approximately 55,000 of the most accomplished men and women from around the world, including luminaries as U.N. Secretary-General Ban Ki-moon. In 2017, Usha was awarded the Marquis Who’s Who Lifetime Achiever Award.",institutionString:null,institution:{name:"RMIT University",institutionURL:null,country:{name:"Australia"}}},editorTwo:null,editorThree:null},subseries:{paginationCount:5,paginationItems:[{id:"91",title:"Sustainable Economy and Fair Society",coverUrl:"https://cdn.intechopen.com/series_topics/covers/91.jpg",isOpenForSubmission:!0,editor:{id:"181603",title:"Dr.",name:"Antonella",middleName:null,surname:"Petrillo",slug:"antonella-petrillo",fullName:"Antonella Petrillo",profilePictureURL:"https://mts.intechopen.com/storage/users/181603/images/system/181603.jpg",biography:"Antonella Petrillo is a Professor at the Department of Engineering of the University of Naples “Parthenope”, Italy. She received her Ph.D. in Mechanical Engineering from the University of Cassino. Her research interests include multi-criteria decision analysis, industrial plant, logistics, manufacturing and safety. She serves as an Associate Editor for the International Journal of the Analytic Hierarchy Process. She is a member of AHP Academy and a member of several editorial boards. She has over 160 Scientific Publications in International Journals and Conferences and she is the author of 5 books on Innovation and Decision Making in Industrial Applications and Engineering.",institutionString:null,institution:{name:"Parthenope University of Naples",institutionURL:null,country:{name:"Italy"}}},editorTwo:null,editorThree:null},{id:"92",title:"Health and Wellbeing",coverUrl:"https://cdn.intechopen.com/series_topics/covers/92.jpg",isOpenForSubmission:!0,editor:{id:"348225",title:"Prof.",name:"Ann",middleName:null,surname:"Hemingway",slug:"ann-hemingway",fullName:"Ann Hemingway",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000035LZFoQAO/Profile_Picture_2022-04-11T14:55:40.jpg",biography:"Professor Hemingway is a public health researcher, Bournemouth University, undertaking international and UK research focused on reducing inequalities in health outcomes for marginalised and excluded populations and more recently focused on equine assisted interventions.",institutionString:null,institution:{name:"Bournemouth University",institutionURL:null,country:{name:"United Kingdom"}}},editorTwo:null,editorThree:null},{id:"93",title:"Inclusivity and Social Equity",coverUrl:"https://cdn.intechopen.com/series_topics/covers/93.jpg",isOpenForSubmission:!0,editor:{id:"210060",title:"Prof. Dr.",name:"Ebba",middleName:null,surname:"Ossiannilsson",slug:"ebba-ossiannilsson",fullName:"Ebba Ossiannilsson",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002g6LkBQAU/Profile_Picture_2022-02-28T13:31:48.png",biography:"Professor Dr. Ebba Ossiannilsson is an independent researcher, expert, consultant, quality auditor and influencer in the fields of open, flexible online and distance learning (OFDL) and the 'new normal'. Her focus is on quality, innovation, leadership, and personalised learning. She works primarily at the strategic and policy levels, both nationally and internationally, and with key international organisations. She is committed to promoting and improving OFDL in the context of SDG4 and the future of education. Ossiannilsson has more than 20 years of experience in her current field, but more than 40 years in the education sector. She works as a reviewer and expert for the European Commission and collaborates with the Joint Research Centre for Quality in Open Education. Ossiannilsson also collaborates with ITCILO and ICoBC (International Council on Badges and Credentials). She is a member of the ICDE Board of Directors and has previously served on the boards of EDEN and EUCEN. Ossiannilsson is a quality expert and reviewer for ICDE, EDEN and the EADTU. She chairs the ICDE OER Advocacy Committee and is a member of the ICDE Quality Network. She is regularly invited as a keynote speaker at conferences. She is a guest editor for several special issues and a member of the editorial board of several scientific journals. She has published more than 200 articles and is currently working on book projects in the field of OFDL. Ossiannilsson is a visiting professor at several international universities and was recently appointed Professor and Research Fellow at Victoria University of Wellington, NZ. Ossiannilsson has been awarded the following fellowships: EDEN Fellows, EDEN Council of Fellows, and Open Education Europe. She is a ICDE OER Ambassador, Open Education Europe Ambassador, GIZ Ambassador for Quality in Digital Learning, and part of the Globe-Community of Digital Learning and Champion of SPARC Europe. On a national level, she is a quality developer at the Swedish Institute for Standards (SIS) and for ISO. 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My method of translating this into day to day in clinical practice is non-exhaustible and my habit of exchanging knowledge and expertise with others in those fields is the code and secret of success.",institutionString:null,institution:{name:"Majmaah University",country:{name:"Saudi Arabia"}}},{id:"313277",title:"Dr.",name:"Bartłomiej",middleName:null,surname:"Płaczek",slug:"bartlomiej-placzek",fullName:"Bartłomiej Płaczek",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/313277/images/system/313277.jpg",biography:"Bartłomiej Płaczek, MSc (2002), Ph.D. (2005), Habilitation (2016), is a professor at the University of Silesia, Institute of Computer Science, Poland, and an expert from the National Centre for Research and Development. His research interests include sensor networks, smart sensors, intelligent systems, and image processing with applications in healthcare and medicine. He is the author or co-author of more than seventy papers in peer-reviewed journals and conferences as well as the co-author of several books. He serves as a reviewer for many scientific journals, international conferences, and research foundations. Since 2010, Dr. Placzek has been a reviewer of grants and projects (including EU projects) in the field of information technologies.",institutionString:"University of Silesia",institution:{name:"University of Silesia",country:{name:"Poland"}}},{id:"35000",title:"Prof.",name:"Ulrich H.P",middleName:"H.P.",surname:"Fischer",slug:"ulrich-h.p-fischer",fullName:"Ulrich H.P Fischer",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/35000/images/3052_n.jpg",biography:"Academic and Professional Background\nUlrich H. P. has Diploma and PhD degrees in Physics from the Free University Berlin, Germany. He has been working on research positions in the Heinrich-Hertz-Institute in Germany. Several international research projects has been performed with European partners from France, Netherlands, Norway and the UK. He is currently Professor of Communications Systems at the Harz University of Applied Sciences, Germany.\n\nPublications and Publishing\nHe has edited one book, a special interest book about ‘Optoelectronic Packaging’ (VDE, Berlin, Germany), and has published over 100 papers and is owner of several international patents for WDM over POF key elements.\n\nKey Research and Consulting Interests\nUlrich’s research activity has always been related to Spectroscopy and Optical Communications Technology. Specific current interests include the validation of complex instruments, and the application of VR technology to the development and testing of measurement systems. He has been reviewer for several publications of the Optical Society of America\\'s including Photonics Technology Letters and Applied Optics.\n\nPersonal Interests\nThese include motor cycling in a very relaxed manner and performing martial arts.",institutionString:null,institution:{name:"Charité",country:{name:"Germany"}}},{id:"341622",title:"Ph.D.",name:"Eduardo",middleName:null,surname:"Rojas Alvarez",slug:"eduardo-rojas-alvarez",fullName:"Eduardo Rojas Alvarez",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/341622/images/15892_n.jpg",biography:null,institutionString:null,institution:{name:"University of Cuenca",country:{name:"Ecuador"}}},{id:"215610",title:"Prof.",name:"Muhammad",middleName:null,surname:"Sarfraz",slug:"muhammad-sarfraz",fullName:"Muhammad Sarfraz",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/215610/images/system/215610.jpeg",biography:"Muhammad Sarfraz is a professor in the Department of Information Science, Kuwait University. His research interests include computer graphics, computer vision, image processing, machine learning, pattern recognition, soft computing, data science, intelligent systems, information technology, and information systems. Prof. Sarfraz has been a keynote/invited speaker on various platforms around the globe. He has advised various students for their MSc and Ph.D. theses. He has published more than 400 publications as books, journal articles, and conference papers. He is a member of various professional societies and a chair and member of the International Advisory Committees and Organizing Committees of various international conferences. Prof. Sarfraz is also an editor-in-chief and editor of various international journals.",institutionString:"Kuwait University",institution:{name:"Kuwait University",country:{name:"Kuwait"}}},{id:"32650",title:"Prof.",name:"Lukas",middleName:"Willem",surname:"Snyman",slug:"lukas-snyman",fullName:"Lukas Snyman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/32650/images/4136_n.jpg",biography:"Lukas Willem Snyman received his basic education at primary and high schools in South Africa, Eastern Cape. He enrolled at today's Nelson Metropolitan University and graduated from this university with a BSc in Physics and Mathematics, B.Sc Honors in Physics, MSc in Semiconductor Physics, and a Ph.D. in Semiconductor Physics in 1987. After his studies, he chose an academic career and devoted his energy to the teaching of physics to first, second, and third-year students. After positions as a lecturer at the University of Port Elizabeth, he accepted a position as Associate Professor at the University of Pretoria, South Africa.\r\n\r\nIn 1992, he motivates the concept of 'television and computer-based education” as means to reach large student numbers with only the best of teaching expertise and publishes an article on the concept in the SA Journal of Higher Education of 1993 (and later in 2003). The University of Pretoria subsequently approved a series of test projects on the concept with outreach to Mamelodi and Eerste Rust in 1993. In 1994, the University established a 'Unit for Telematic Education ' as a support section for multiple faculties at the University of Pretoria. In subsequent years, the concept of 'telematic education” subsequently becomes well established in academic circles in South Africa, grew in popularity, and is adopted by many universities and colleges throughout South Africa as a medium of enhancing education and training, as a method to reaching out to far out communities, and as a means to enhance study from the home environment.\r\n\r\nProfessor Snyman in subsequent years pursued research in semiconductor physics, semiconductor devices, microelectronics, and optoelectronics.\r\n\r\nIn 2000 he joined the TUT as a full professor. Here served for a period as head of the Department of Electronic Engineering. Here he makes contributions to solar energy development, microwave and optoelectronic device development, silicon photonics, as well as contributions to new mobile telecommunication systems and network planning in SA.\r\n\r\nCurrently, he teaches electronics and telecommunications at the TUT to audiences ranging from first-year students to Ph.D. level.\r\n\r\nFor his research in the field of 'Silicon Photonics” since 1990, he has published (as author and co-author) about thirty internationally reviewed articles in scientific journals, contributed to more than forty international conferences, about 25 South African provisional patents (as inventor and co-inventor), 8 PCT international patent applications until now. Of these, two USA patents applications, two European Patents, two Korean patents, and ten SA patents have been granted. A further 4 USA patents, 5 European patents, 3 Korean patents, 3 Chinese patents, and 3 Japanese patents are currently under consideration.\r\n\r\nRecently he has also published an extensive scholarly chapter in an internet open access book on 'Integrating Microphotonic Systems and MOEMS into standard Silicon CMOS Integrated circuitry”.\r\n\r\nFurthermore, Professor Snyman recently steered a new initiative at the TUT by introducing a 'Laboratory for Innovative Electronic Systems ' at the Department of Electrical Engineering. The model of this laboratory or center is to primarily combine outputs as achieved by high-level research with lower-level system development and entrepreneurship in a technical university environment. Students are allocated to projects at different levels with PhDs and Master students allocated to the generation of new knowledge and new technologies, while students at the diploma and Baccalaureus level are allocated to electronic systems development with a direct and a near application for application in industry or the commercial and public sectors in South Africa.\r\n\r\nProfessor Snyman received the WIRSAM Award of 1983 and the WIRSAM Award in 1985 in South Africa for best research papers by a young scientist at two international conferences on electron microscopy in South Africa. He subsequently received the SA Microelectronics Award for the best dissertation emanating from studies executed at a South African university in the field of Physics and Microelectronics in South Africa in 1987. In October of 2011, Professor Snyman received the prestigious Institutional Award for 'Innovator of the Year” for 2010 at the Tshwane University of Technology, South Africa. This award was based on the number of patents recognized and granted by local and international institutions as well as for his contributions concerning innovation at the TUT.",institutionString:null,institution:{name:"University of South Africa",country:{name:"South Africa"}}},{id:"317279",title:"Mr.",name:"Ali",middleName:"Usama",surname:"Syed",slug:"ali-syed",fullName:"Ali Syed",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/317279/images/16024_n.png",biography:"A creative, talented, and innovative young professional who is dedicated, well organized, and capable research fellow with two years of experience in graduate-level research, published in engineering journals and book, with related expertise in Bio-robotics, equally passionate about the aesthetics of the mechanical and electronic system, obtained expertise in the use of MS Office, MATLAB, SolidWorks, LabVIEW, Proteus, Fusion 360, having a grasp on python, C++ and assembly language, possess proven ability in acquiring research grants, previous appointments with social and educational societies with experience in administration, current affiliations with IEEE and Web of Science, a confident presenter at conferences and teacher in classrooms, able to explain complex information to audiences of all levels.",institutionString:null,institution:{name:"Air University",country:{name:"Pakistan"}}},{id:"75526",title:"Ph.D.",name:"Zihni Onur",middleName:null,surname:"Uygun",slug:"zihni-onur-uygun",fullName:"Zihni Onur Uygun",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/75526/images/12_n.jpg",biography:"My undergraduate education and my Master of Science educations at Ege University and at Çanakkale Onsekiz Mart University have given me a firm foundation in Biochemistry, Analytical Chemistry, Biosensors, Bioelectronics, Physical Chemistry and Medicine. After obtaining my degree as a MSc in analytical chemistry, I started working as a research assistant in Ege University Medical Faculty in 2014. In parallel, I enrolled to the MSc program at the Department of Medical Biochemistry at Ege University to gain deeper knowledge on medical and biochemical sciences as well as clinical chemistry in 2014. In my PhD I deeply researched on biosensors and bioelectronics and finished in 2020. Now I have eleven SCI-Expanded Index published papers, 6 international book chapters, referee assignments for different SCIE journals, one international patent pending, several international awards, projects and bursaries. In parallel to my research assistant position at Ege University Medical Faculty, Department of Medical Biochemistry, in April 2016, I also founded a Start-Up Company (Denosens Biotechnology LTD) by the support of The Scientific and Technological Research Council of Turkey. Currently, I am also working as a CEO in Denosens Biotechnology. The main purposes of the company, which carries out R&D as a research center, are to develop new generation biosensors and sensors for both point-of-care diagnostics; such as glucose, lactate, cholesterol and cancer biomarker detections. My specific experimental and instrumental skills are Biochemistry, Biosensor, Analytical Chemistry, Electrochemistry, Mobile phone based point-of-care diagnostic device, POCTs and Patient interface designs, HPLC, Tandem Mass Spectrometry, Spectrophotometry, ELISA.",institutionString:null,institution:{name:"Ege University",country:{name:"Turkey"}}},{id:"267434",title:"Dr.",name:"Rohit",middleName:null,surname:"Raja",slug:"rohit-raja",fullName:"Rohit Raja",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/267434/images/system/267434.jpg",biography:"Dr. Rohit Raja received Ph.D. in Computer Science and Engineering from Dr. CVRAMAN University in 2016. His main research interest includes Face recognition and Identification, Digital Image Processing, Signal Processing, and Networking. Presently he is working as Associate Professor in IT Department, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur (CG), India. He has authored several Journal and Conference Papers. He has good Academics & Research experience in various areas of CSE and IT. He has filed and successfully published 27 Patents. He has received many time invitations to be a Guest at IEEE Conferences. He has published 100 research papers in various International/National Journals (including IEEE, Springer, etc.) and Proceedings of the reputed International/ National Conferences (including Springer and IEEE). He has been nominated to the board of editors/reviewers of many peer-reviewed and refereed Journals (including IEEE, Springer).",institutionString:"Guru Ghasidas Vishwavidyalaya",institution:{name:"Guru Ghasidas Vishwavidyalaya",country:{name:"India"}}},{id:"246502",title:"Dr.",name:"Jaya T.",middleName:"T",surname:"Varkey",slug:"jaya-t.-varkey",fullName:"Jaya T. Varkey",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/246502/images/11160_n.jpg",biography:"Jaya T. Varkey, PhD, graduated with a degree in Chemistry from Cochin University of Science and Technology, Kerala, India. She obtained a PhD in Chemistry from the School of Chemical Sciences, Mahatma Gandhi University, Kerala, India, and completed a post-doctoral fellowship at the University of Minnesota, USA. She is a research guide at Mahatma Gandhi University and Associate Professor in Chemistry, St. Teresa’s College, Kochi, Kerala, India.\nDr. Varkey received a National Young Scientist award from the Indian Science Congress (1995), a UGC Research award (2016–2018), an Indian National Science Academy (INSA) Visiting Scientist award (2018–2019), and a Best Innovative Faculty award from the All India Association for Christian Higher Education (AIACHE) (2019). She Hashas received the Sr. Mary Cecil prize for best research paper three times. She was also awarded a start-up to develop a tea bag water filter. \nDr. Varkey has published two international books and twenty-seven international journal publications. She is an editorial board member for five international journals.",institutionString:"St. Teresa’s College",institution:null},{id:"250668",title:"Dr.",name:"Ali",middleName:null,surname:"Nabipour Chakoli",slug:"ali-nabipour-chakoli",fullName:"Ali Nabipour Chakoli",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/250668/images/system/250668.jpg",biography:"Academic Qualification:\r\n•\tPhD in Materials Physics and Chemistry, From: Sep. 2006, to: Sep. 2010, School of Materials Science and Engineering, Harbin Institute of Technology, Thesis: Structure and Shape Memory Effect of Functionalized MWCNTs/poly (L-lactide-co-ε-caprolactone) Nanocomposites. Supervisor: Prof. Wei Cai,\r\n•\tM.Sc in Applied Physics, From: 1996, to: 1998, Faculty of Physics & Nuclear Science, Amirkabir Uni. of Technology, Tehran, Iran, Thesis: Determination of Boron in Micro alloy Steels with solid state nuclear track detectors by neutron induced auto radiography, Supervisors: Dr. M. Hosseini Ashrafi and Dr. A. Hosseini.\r\n•\tB.Sc. in Applied Physics, From: 1991, to: 1996, Faculty of Physics & Nuclear Science, Amirkabir Uni. of Technology, Tehran, Iran, Thesis: Design of shielding for Am-Be neutron sources for In Vivo neutron activation analysis, Supervisor: Dr. M. Hosseini Ashrafi.\r\n\r\nResearch Experiences:\r\n1.\tNanomaterials, Carbon Nanotubes, Graphene: Synthesis, Functionalization and Characterization,\r\n2.\tMWCNTs/Polymer Composites: Fabrication and Characterization, \r\n3.\tShape Memory Polymers, Biodegradable Polymers, ORC, Collagen,\r\n4.\tMaterials Analysis and Characterizations: TEM, SEM, XPS, FT-IR, Raman, DSC, DMA, TGA, XRD, GPC, Fluoroscopy, \r\n5.\tInteraction of Radiation with Mater, Nuclear Safety and Security, NDT(RT),\r\n6.\tRadiation Detectors, Calibration (SSDL),\r\n7.\tCompleted IAEA e-learning Courses:\r\nNuclear Security (15 Modules),\r\nNuclear Safety:\r\nTSA 2: Regulatory Protection in Occupational Exposure,\r\nTips & Tricks: Radiation Protection in Radiography,\r\nSafety and Quality in Radiotherapy,\r\nCourse on Sealed Radioactive Sources,\r\nCourse on Fundamentals of Environmental Remediation,\r\nCourse on Planning for Environmental Remediation,\r\nKnowledge Management Orientation Course,\r\nFood Irradiation - Technology, Applications and Good Practices,\r\nEmployment:\r\nFrom 2010 to now: Academic staff, Nuclear Science and Technology Research Institute, Kargar Shomali, Tehran, Iran, P.O. Box: 14395-836.\r\nFrom 1997 to 2006: Expert of Materials Analysis and Characterization. Research Center of Agriculture and Medicine. Rajaeeshahr, Karaj, Iran, P. O. Box: 31585-498.",institutionString:"Atomic Energy Organization of Iran",institution:{name:"Atomic Energy Organization of Iran",country:{name:"Iran"}}},{id:"248279",title:"Dr.",name:"Monika",middleName:"Elzbieta",surname:"Machoy",slug:"monika-machoy",fullName:"Monika Machoy",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/248279/images/system/248279.jpeg",biography:"Monika Elżbieta Machoy, MD, graduated with distinction from the Faculty of Medicine and Dentistry at the Pomeranian Medical University in 2009, defended her PhD thesis with summa cum laude in 2016 and is currently employed as a researcher at the Department of Orthodontics of the Pomeranian Medical University. She expanded her professional knowledge during a one-year scholarship program at the Ernst Moritz Arndt University in Greifswald, Germany and during a three-year internship at the Technical University in Dresden, Germany. She has been a speaker at numerous orthodontic conferences, among others, American Association of Orthodontics, European Orthodontic Symposium and numerous conferences of the Polish Orthodontic Society. She conducts research focusing on the effect of orthodontic treatment on dental and periodontal tissues and the causes of pain in orthodontic patients.",institutionString:"Pomeranian Medical University",institution:{name:"Pomeranian Medical University",country:{name:"Poland"}}},{id:"252743",title:"Prof.",name:"Aswini",middleName:"Kumar",surname:"Kar",slug:"aswini-kar",fullName:"Aswini Kar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/252743/images/10381_n.jpg",biography:"uploaded in cv",institutionString:null,institution:{name:"KIIT University",country:{name:"India"}}},{id:"204256",title:"Dr.",name:"Anil",middleName:"Kumar",surname:"Kumar Sahu",slug:"anil-kumar-sahu",fullName:"Anil Kumar Sahu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/204256/images/14201_n.jpg",biography:"I have nearly 11 years of research and teaching experience. I have done my master degree from University Institute of Pharmacy, Pt. Ravi Shankar Shukla University, Raipur, Chhattisgarh India. I have published 16 review and research articles in international and national journals and published 4 chapters in IntechOpen, the world’s leading publisher of Open access books. I have presented many papers at national and international conferences. I have received research award from Indian Drug Manufacturers Association in year 2015. My research interest extends from novel lymphatic drug delivery systems, oral delivery system for herbal bioactive to formulation optimization.",institutionString:null,institution:{name:"Chhattisgarh Swami Vivekanand Technical University",country:{name:"India"}}},{id:"253468",title:"Dr.",name:"Mariusz",middleName:null,surname:"Marzec",slug:"mariusz-marzec",fullName:"Mariusz Marzec",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/253468/images/system/253468.png",biography:"An assistant professor at Department of Biomedical Computer Systems, at Institute of Computer Science, Silesian University in Katowice. Scientific interests: computer analysis and processing of images, biomedical images, databases and programming languages. He is an author and co-author of scientific publications covering analysis and processing of biomedical images and development of database systems.",institutionString:"University of Silesia",institution:null},{id:"212432",title:"Prof.",name:"Hadi",middleName:null,surname:"Mohammadi",slug:"hadi-mohammadi",fullName:"Hadi Mohammadi",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/212432/images/system/212432.jpeg",biography:"Dr. Hadi Mohammadi is a biomedical engineer with hands-on experience in the design and development of many engineering structures and medical devices through various projects that he has been involved in over the past twenty years. Dr. Mohammadi received his BSc. and MSc. degrees in Mechanical Engineering from Sharif University of Technology, Tehran, Iran, and his PhD. degree in Biomedical Engineering (biomaterials) from the University of Western Ontario. He was a postdoctoral trainee for almost four years at University of Calgary and Harvard Medical School. He is an industry innovator having created the technology to produce lifelike synthetic platforms that can be used for the simulation of almost all cardiovascular reconstructive surgeries. He’s been heavily involved in the design and development of cardiovascular devices and technology for the past 10 years. He is currently an Assistant Professor with the University of British Colombia, Canada.",institutionString:"University of British Columbia",institution:{name:"University of British Columbia",country:{name:"Canada"}}},{id:"254463",title:"Prof.",name:"Haisheng",middleName:null,surname:"Yang",slug:"haisheng-yang",fullName:"Haisheng Yang",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/254463/images/system/254463.jpeg",biography:"Haisheng Yang, Ph.D., Professor and Director of the Department of Biomedical Engineering, College of Life Science and Bioengineering, Beijing University of Technology. He received his Ph.D. degree in Mechanics/Biomechanics from Harbin Institute of Technology (jointly with University of California, Berkeley). Afterwards, he worked as a Postdoctoral Research Associate in the Purdue Musculoskeletal Biology and Mechanics Lab at the Department of Basic Medical Sciences, Purdue University, USA. He also conducted research in the Research Centre of Shriners Hospitals for Children-Canada at McGill University, Canada. Dr. Yang has over 10 years research experience in orthopaedic biomechanics and mechanobiology of bone adaptation and regeneration. He earned an award from Beijing Overseas Talents Aggregation program in 2017 and serves as Beijing Distinguished Professor.",institutionString:null,institution:{name:"Beijing University of Technology",country:{name:"China"}}},{id:"89721",title:"Dr.",name:"Mehmet",middleName:"Cuneyt",surname:"Ozmen",slug:"mehmet-ozmen",fullName:"Mehmet Ozmen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/89721/images/7289_n.jpg",biography:null,institutionString:null,institution:{name:"Gazi University",country:{name:"Turkey"}}},{id:"243698",title:"M.D.",name:"Xiaogang",middleName:null,surname:"Wang",slug:"xiaogang-wang",fullName:"Xiaogang Wang",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/243698/images/system/243698.png",biography:"Dr. Xiaogang Wang, a faculty member of Shanxi Eye Hospital specializing in the treatment of cataract and retinal disease and a tutor for postgraduate students of Shanxi Medical University, worked in the COOL Lab as an international visiting scholar under the supervision of Dr. David Huang and Yali Jia from October 2012 through November 2013. Dr. Wang earned an MD from Shanxi Medical University and a Ph.D. from Shanghai Jiao Tong University. Dr. Wang was awarded two research project grants focused on multimodal optical coherence tomography imaging and deep learning in cataract and retinal disease, from the National Natural Science Foundation of China. He has published around 30 peer-reviewed journal papers and four book chapters and co-edited one book.",institutionString:"Shanxi Eye Hospital",institution:{name:"Shanxi Eye Hospital",country:{name:"China"}}},{id:"242893",title:"Ph.D. Student",name:"Joaquim",middleName:null,surname:"De Moura",slug:"joaquim-de-moura",fullName:"Joaquim De Moura",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/242893/images/7133_n.jpg",biography:"Joaquim de Moura received his degree in Computer Engineering in 2014 from the University of A Coruña (Spain). In 2016, he received his M.Sc degree in Computer Engineering from the same university. He is currently pursuing his Ph.D degree in Computer Science in a collaborative project between ophthalmology centers in Galicia and the University of A Coruña. His research interests include computer vision, machine learning algorithms and analysis and medical imaging processing of various kinds.",institutionString:null,institution:{name:"University of A Coruña",country:{name:"Spain"}}},{id:"294334",title:"B.Sc.",name:"Marc",middleName:null,surname:"Bruggeman",slug:"marc-bruggeman",fullName:"Marc Bruggeman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/294334/images/8242_n.jpg",biography:"Chemical engineer graduate, with a passion for material science and specific interest in polymers - their near infinite applications intrigue me. \n\nI plan to continue my scientific career in the field of polymeric biomaterials as I am fascinated by intelligent, bioactive and biomimetic materials for use in both consumer and medical applications.",institutionString:null,institution:null},{id:"255757",title:"Dr.",name:"Igor",middleName:"Victorovich",surname:"Lakhno",slug:"igor-lakhno",fullName:"Igor Lakhno",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/255757/images/system/255757.jpg",biography:"Igor Victorovich Lakhno was born in 1971 in Kharkiv (Ukraine). \nMD – 1994, Kharkiv National Medical Univesity.\nOb&Gyn; – 1997, master courses in Kharkiv Medical Academy of Postgraduate Education.\nPh.D. – 1999, Kharkiv National Medical Univesity.\nDSC – 2019, PL Shupik National Academy of Postgraduate Education \nProfessor – 2021, Department of Obstetrics and Gynecology of VN Karazin Kharkiv National University\nHead of Department – 2021, Department of Perinatology, Obstetrics and gynecology of Kharkiv Medical Academy of Postgraduate Education\nIgor Lakhno has been graduated from international training courses on reproductive medicine and family planning held at Debrecen University (Hungary) in 1997. Since 1998 Lakhno Igor has worked as an associate professor in the department of obstetrics and gynecology of VN Karazin National University and an associate professor of the perinatology, obstetrics, and gynecology department of Kharkiv Medical Academy of Postgraduate Education. Since June 2019 he’s been a professor in the department of obstetrics and gynecology of VN Karazin National University and a professor of the perinatology, obstetrics, and gynecology department. He’s affiliated with Kharkiv Medical Academy of Postgraduate Education as a Head of Department from November 2021. Igor Lakhno has participated in several international projects on fetal non-invasive electrocardiography (with Dr. J. A. Behar (Technion), Prof. D. Hoyer (Jena University), and José Alejandro Díaz Méndez (National Institute of Astrophysics, Optics, and Electronics, Mexico). He’s an author of about 200 printed works and there are 31 of them in Scopus or Web of Science databases. Igor Lakhno is a member of the Editorial Board of Reproductive Health of Woman, Emergency Medicine, and Technology Transfer Innovative Solutions in Medicine (Estonia). He is a medical Editor of “Z turbotoyu pro zhinku”. Igor Lakhno is a reviewer of the Journal of Obstetrics and Gynaecology (Taylor and Francis), British Journal of Obstetrics and Gynecology (Wiley), Informatics in Medicine Unlocked (Elsevier), The Journal of Obstetrics and Gynecology Research (Wiley), Endocrine, Metabolic & Immune Disorders-Drug Targets (Bentham Open), The Open Biomedical Engineering Journal (Bentham Open), etc. He’s defended a dissertation for a DSc degree “Pre-eclampsia: prediction, prevention, and treatment”. Three years ago Igor Lakhno has participated in a training course on innovative technologies in medical education at Lublin Medical University (Poland). Lakhno Igor has participated as a speaker in several international conferences and congresses (International Conference on Biological Oscillations April 10th-14th 2016, Lancaster, UK, The 9th conference of the European Study Group on Cardiovascular Oscillations). His main scientific interests: are obstetrics, women’s health, fetal medicine, and cardiovascular medicine. \nIgor Lakhno is a consultant at Kharkiv municipal perinatal center. He’s graduated from training courses on endoscopy in gynecology. He has 28 years of practical experience in the field.",institutionString:null,institution:null},{id:"244950",title:"Dr.",name:"Salvatore",middleName:null,surname:"Di Lauro",slug:"salvatore-di-lauro",fullName:"Salvatore Di Lauro",position:null,profilePictureURL:"https://intech-files.s3.amazonaws.com/0030O00002bSF1HQAW/ProfilePicture%202021-12-20%2014%3A54%3A14.482",biography:"Name:\n\tSALVATORE DI LAURO\nAddress:\n\tHospital Clínico Universitario Valladolid\nAvda Ramón y Cajal 3\n47005, Valladolid\nSpain\nPhone number: \nFax\nE-mail:\n\t+34 983420000 ext 292\n+34 983420084\nsadilauro@live.it\nDate and place of Birth:\nID Number\nMedical Licence \nLanguages\t09-05-1985. Villaricca (Italy)\n\nY1281863H\n474707061\nItalian (native language)\nSpanish (read, written, spoken)\nEnglish (read, written, spoken)\nPortuguese (read, spoken)\nFrench (read)\n\t\t\nCurrent position (title and company)\tDate (Year)\nVitreo-Retinal consultant in ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl. National Health System.\nVitreo-Retinal consultant in ophthalmology. Instituto Oftalmologico Recoletas. Red Hospitalaria Recoletas. Private practise.\t2017-today\n\n2019-today\n\t\n\t\nEducation (High school, university and postgraduate training > 3 months)\tDate (Year)\nDegree in Medicine and Surgery. University of Neaples 'Federico II”\nResident in Opthalmology. Hospital Clinico Universitario Valladolid\nMaster in Vitreo-Retina. IOBA. University of Valladolid\nFellow of the European Board of Ophthalmology. Paris\nMaster in Research in Ophthalmology. University of Valladolid\t2003-2009\n2012-2016\n2016-2017\n2016\n2012-2013\n\t\nEmployments (company and positions)\tDate (Year)\nResident in Ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl.\nFellow in Vitreo-Retina. IOBA. University of Valladolid\nVitreo-Retinal consultant in ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl. National Health System.\nVitreo-Retinal consultant in ophthalmology. Instituto Oftalmologico Recoletas. Red Hospitalaria Recoletas. \n\t2012-2016\n2016-2017\n2017-today\n\n2019-Today\n\n\n\t\nClinical Research Experience (tasks and role)\tDate (Year)\nAssociated investigator\n\n' FIS PI20/00740: DESARROLLO DE UNA CALCULADORA DE RIESGO DE\nAPARICION DE RETINOPATIA DIABETICA BASADA EN TECNICAS DE IMAGEN MULTIMODAL EN PACIENTES DIABETICOS TIPO 1. Grant by: Ministerio de Ciencia e Innovacion \n\n' (BIO/VA23/14) Estudio clínico multicéntrico y prospectivo para validar dos\nbiomarcadores ubicados en los genes p53 y MDM2 en la predicción de los resultados funcionales de la cirugía del desprendimiento de retina regmatógeno. Grant by: Gerencia Regional de Salud de la Junta de Castilla y León.\n' Estudio multicéntrico, aleatorizado, con enmascaramiento doble, en 2 grupos\nparalelos y de 52 semanas de duración para comparar la eficacia, seguridad e inmunogenicidad de SOK583A1 respecto a Eylea® en pacientes con degeneración macular neovascular asociada a la edad' (CSOK583A12301; N.EUDRA: 2019-004838-41; FASE III). Grant by Hexal AG\n\n' Estudio de fase III, aleatorizado, doble ciego, con grupos paralelos, multicéntrico para comparar la eficacia y la seguridad de QL1205 frente a Lucentis® en pacientes con degeneración macular neovascular asociada a la edad. (EUDRACT: 2018-004486-13). Grant by Qilu Pharmaceutical Co\n\n' Estudio NEUTON: Ensayo clinico en fase IV para evaluar la eficacia de aflibercept en pacientes Naive con Edema MacUlar secundario a Oclusion de Vena CenTral de la Retina (OVCR) en regimen de tratamientO iNdividualizado Treat and Extend (TAE)”, (2014-000975-21). Grant by Fundacion Retinaplus\n\n' Evaluación de la seguridad y bioactividad de anillos de tensión capsular en conejo. Proyecto Procusens. Grant by AJL, S.A.\n\n'Estudio epidemiológico, prospectivo, multicéntrico y abierto\\npara valorar la frecuencia de la conjuntivitis adenovírica diagnosticada mediante el test AdenoPlus®\\nTest en pacientes enfermos de conjuntivitis aguda”\\n. National, multicenter study. Grant by: NICOX.\n\nEuropean multicentric trial: 'Evaluation of clinical outcomes following the use of Systane Hydration in patients with dry eye”. Study Phase 4. Grant by: Alcon Labs'\n\nVLPs Injection and Activation in a Rabbit Model of Uveal Melanoma. Grant by Aura Bioscience\n\nUpdating and characterization of a rabbit model of uveal melanoma. Grant by Aura Bioscience\n\nEnsayo clínico en fase IV para evaluar las variantes genéticas de la vía del VEGF como biomarcadores de eficacia del tratamiento con aflibercept en pacientes con degeneración macular asociada a la edad (DMAE) neovascular. Estudio BIOIMAGE. IMO-AFLI-2013-01\n\nEstudio In-Eye:Ensayo clínico en fase IV, abierto, aleatorizado, de 2 brazos,\nmulticçentrico y de 12 meses de duración, para evaluar la eficacia y seguridad de un régimen de PRN flexible individualizado de 'esperar y extender' versus un régimen PRN según criterios de estabilización mediante evaluaciones mensuales de inyecciones intravítreas de ranibizumab 0,5 mg en pacientes naive con neovascularización coriodea secunaria a la degeneración macular relacionada con la edad. CP: CRFB002AES03T\n\nTREND: Estudio Fase IIIb multicéntrico, randomizado, de 12 meses de\nseguimiento con evaluador de la agudeza visual enmascarado, para evaluar la eficacia y la seguridad de ranibizumab 0.5mg en un régimen de tratar y extender comparado con un régimen mensual, en pacientes con degeneración macular neovascular asociada a la edad. CP: CRFB002A2411 Código Eudra CT:\n2013-002626-23\n\n\n\nPublications\t\n\n2021\n\n\n\n\n2015\n\n\n\n\n2021\n\n\n\n\n\n2021\n\n\n\n\n2015\n\n\n\n\n2015\n\n\n2014\n\n\n\n\n2015-16\n\n\n\n2015\n\n\n2014\n\n\n2014\n\n\n\n\n2014\n\n\n\n\n\n\n\n2014\n\nJose Carlos Pastor; Jimena Rojas; Salvador Pastor-Idoate; Salvatore Di Lauro; Lucia Gonzalez-Buendia; Santiago Delgado-Tirado. Proliferative vitreoretinopathy: A new concept of disease pathogenesis and practical\nconsequences. Progress in Retinal and Eye Research. 51, pp. 125 - 155. 03/2016. DOI: 10.1016/j.preteyeres.2015.07.005\n\n\nLabrador-Velandia S; Alonso-Alonso ML; Di Lauro S; García-Gutierrez MT; Srivastava GK; Pastor JC; Fernandez-Bueno I. Mesenchymal stem cells provide paracrine neuroprotective resources that delay degeneration of co-cultured organotypic neuroretinal cultures.Experimental Eye Research. 185, 17/05/2019. DOI: 10.1016/j.exer.2019.05.011\n\nSalvatore Di Lauro; Maria Teresa Garcia Gutierrez; Ivan Fernandez Bueno. Quantification of pigment epithelium-derived factor (PEDF) in an ex vivo coculture of retinal pigment epithelium cells and neuroretina.\nJournal of Allbiosolution. 2019. ISSN 2605-3535\n\nSonia Labrador Velandia; Salvatore Di Lauro; Alonso-Alonso ML; Tabera Bartolomé S; Srivastava GK; Pastor JC; Fernandez-Bueno I. Biocompatibility of intravitreal injection of human mesenchymal stem cells in immunocompetent rabbits. Graefe's archive for clinical and experimental ophthalmology. 256 - 1, pp. 125 - 134. 01/2018. DOI: 10.1007/s00417-017-3842-3\n\n\nSalvatore Di Lauro, David Rodriguez-Crespo, Manuel J Gayoso, Maria T Garcia-Gutierrez, J Carlos Pastor, Girish K Srivastava, Ivan Fernandez-Bueno. A novel coculture model of porcine central neuroretina explants and retinal pigment epithelium cells. Molecular Vision. 2016 - 22, pp. 243 - 253. 01/2016.\n\nSalvatore Di Lauro. Classifications for Proliferative Vitreoretinopathy ({PVR}): An Analysis of Their Use in Publications over the Last 15 Years. Journal of Ophthalmology. 2016, pp. 1 - 6. 01/2016. DOI: 10.1155/2016/7807596\n\nSalvatore Di Lauro; Rosa Maria Coco; Rosa Maria Sanabria; Enrique Rodriguez de la Rua; Jose Carlos Pastor. Loss of Visual Acuity after Successful Surgery for Macula-On Rhegmatogenous Retinal Detachment in a Prospective Multicentre Study. Journal of Ophthalmology. 2015:821864, 2015. DOI: 10.1155/2015/821864\n\nIvan Fernandez-Bueno; Salvatore Di Lauro; Ivan Alvarez; Jose Carlos Lopez; Maria Teresa Garcia-Gutierrez; Itziar Fernandez; Eva Larra; Jose Carlos Pastor. Safety and Biocompatibility of a New High-Density Polyethylene-Based\nSpherical Integrated Porous Orbital Implant: An Experimental Study in Rabbits. Journal of Ophthalmology. 2015:904096, 2015. DOI: 10.1155/2015/904096\n\nPastor JC; Pastor-Idoate S; Rodríguez-Hernandez I; Rojas J; Fernandez I; Gonzalez-Buendia L; Di Lauro S; Gonzalez-Sarmiento R. Genetics of PVR and RD. Ophthalmologica. 232 - Suppl 1, pp. 28 - 29. 2014\n\nRodriguez-Crespo D; Di Lauro S; Singh AK; Garcia-Gutierrez MT; Garrosa M; Pastor JC; Fernandez-Bueno I; Srivastava GK. Triple-layered mixed co-culture model of RPE cells with neuroretina for evaluating the neuroprotective effects of adipose-MSCs. Cell Tissue Res. 358 - 3, pp. 705 - 716. 2014.\nDOI: 10.1007/s00441-014-1987-5\n\nCarlo De Werra; Salvatore Condurro; Salvatore Tramontano; Mario Perone; Ivana Donzelli; Salvatore Di Lauro; Massimo Di Giuseppe; Rosa Di Micco; Annalisa Pascariello; Antonio Pastore; Giorgio Diamantis; Giuseppe Galloro. Hydatid disease of the liver: thirty years of surgical experience.Chirurgia italiana. 59 - 5, pp. 611 - 636.\n(Italia): 2007. ISSN 0009-4773\n\nChapters in books\n\t\n' Salvador Pastor Idoate; Salvatore Di Lauro; Jose Carlos Pastor Jimeno. PVR: Pathogenesis, Histopathology and Classification. Proliferative Vitreoretinopathy with Small Gauge Vitrectomy. Springer, 2018. ISBN 978-3-319-78445-8\nDOI: 10.1007/978-3-319-78446-5_2. \n\n' Salvatore Di Lauro; Maria Isabel Lopez Galvez. Quistes vítreos en una mujer joven. Problemas diagnósticos en patología retinocoroidea. Sociedad Española de Retina-Vitreo. 2018.\n\n' Salvatore Di Lauro; Salvador Pastor Idoate; Jose Carlos Pastor Jimeno. iOCT in PVR management. OCT Applications in Opthalmology. pp. 1 - 8. INTECH, 2018. DOI: 10.5772/intechopen.78774.\n\n' Rosa Coco Martin; Salvatore Di Lauro; Salvador Pastor Idoate; Jose Carlos Pastor. amponadores, manipuladores y tinciones en la cirugía del traumatismo ocular.Trauma Ocular. Ponencia de la SEO 2018..\n\n' LOPEZ GALVEZ; DI LAURO; CRESPO. OCT angiografia y complicaciones retinianas de la diabetes. PONENCIA SEO 2021, CAPITULO 20. (España): 2021.\n\n' Múltiples desprendimientos neurosensoriales bilaterales en paciente joven. Enfermedades Degenerativas De Retina Y Coroides. SERV 04/2016. \n' González-Buendía L; Di Lauro S; Pastor-Idoate S; Pastor Jimeno JC. Vitreorretinopatía proliferante (VRP) e inflamación: LA INFLAMACIÓN in «INMUNOMODULADORES Y ANTIINFLAMATORIOS: MÁS ALLÁ DE LOS CORTICOIDES. RELACION DE PONENCIAS DE LA SOCIEDAD ESPAÑOLA DE OFTALMOLOGIA. 10/2014.",institutionString:null,institution:null},{id:"265335",title:"Mr.",name:"Stefan",middleName:"Radnev",surname:"Stefanov",slug:"stefan-stefanov",fullName:"Stefan Stefanov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/265335/images/7562_n.jpg",biography:null,institutionString:null,institution:null},{id:"7227",title:"Dr.",name:"Hiroaki",middleName:null,surname:"Matsui",slug:"hiroaki-matsui",fullName:"Hiroaki Matsui",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Tokyo",country:{name:"Japan"}}},{id:"318905",title:"Prof.",name:"Elvis",middleName:"Kwason",surname:"Tiburu",slug:"elvis-tiburu",fullName:"Elvis Tiburu",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Ghana",country:{name:"Ghana"}}},{id:"336193",title:"Dr.",name:"Abdullah",middleName:null,surname:"Alamoudi",slug:"abdullah-alamoudi",fullName:"Abdullah Alamoudi",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Majmaah University",country:{name:"Saudi Arabia"}}},{id:"318657",title:"MSc.",name:"Isabell",middleName:null,surname:"Steuding",slug:"isabell-steuding",fullName:"Isabell Steuding",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Harz University of Applied Sciences",country:{name:"Germany"}}},{id:"318656",title:"BSc.",name:"Peter",middleName:null,surname:"Kußmann",slug:"peter-kussmann",fullName:"Peter Kußmann",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Harz University of Applied Sciences",country:{name:"Germany"}}},{id:"338222",title:"Mrs.",name:"María José",middleName:null,surname:"Lucía Mudas",slug:"maria-jose-lucia-mudas",fullName:"María José Lucía Mudas",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Carlos III University of Madrid",country:{name:"Spain"}}}]}},subseries:{item:{id:"14",type:"subseries",title:"Cell and Molecular Biology",keywords:"Omics (Transcriptomics; Proteomics; Metabolomics), Molecular Biology, Cell Biology, Signal Transduction and Regulation, Cell Growth and Differentiation, Apoptosis, Necroptosis, Ferroptosis, Autophagy, Cell Cycle, Macromolecules and Complexes, Gene Expression",scope:"The Cell and Molecular Biology topic within the IntechOpen Biochemistry Series aims to rapidly publish contributions on all aspects of cell and molecular biology, including aspects related to biochemical and genetic research (not only in humans but all living beings). We encourage the submission of manuscripts that provide novel and mechanistic insights that report significant advances in the fields. Topics include, but are not limited to: Advanced techniques of cellular and molecular biology (Molecular methodologies, imaging techniques, and bioinformatics); Biological activities at the molecular level; Biological processes of cell functions, cell division, senescence, maintenance, and cell death; Biomolecules interactions; Cancer; Cell biology; Chemical biology; Computational biology; Cytochemistry; Developmental biology; Disease mechanisms and therapeutics; DNA, and RNA metabolism; Gene functions, genetics, and genomics; Genetics; Immunology; Medical microbiology; Molecular biology; Molecular genetics; Molecular processes of cell and organelle dynamics; Neuroscience; Protein biosynthesis, degradation, and functions; Regulation of molecular interactions in a cell; Signalling networks and system biology; Structural biology; Virology and microbiology.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/14.jpg",hasOnlineFirst:!0,hasPublishedBooks:!0,annualVolume:11410,editor:{id:"165627",title:"Dr.",name:"Rosa María",middleName:null,surname:"Martínez-Espinosa",slug:"rosa-maria-martinez-espinosa",fullName:"Rosa María Martínez-Espinosa",profilePictureURL:"https://mts.intechopen.com/storage/users/165627/images/system/165627.jpeg",biography:"Dr. Rosa María Martínez-Espinosa has been a Spanish Full Professor since 2020 (Biochemistry and Molecular Biology) and is currently Vice-President of International Relations and Cooperation development and leader of the research group 'Applied Biochemistry” (University of Alicante, Spain). Other positions she has held at the university include Vice-Dean of Master Programs, Vice-Dean of the Degree in Biology and Vice-Dean for Mobility and Enterprise and Engagement at the Faculty of Science (University of Alicante). She received her Bachelor in Biology in 1998 (University of Alicante) and her PhD in 2003 (Biochemistry, University of Alicante). She undertook post-doctoral research at the University of East Anglia (Norwich, U.K. 2004-2005; 2007-2008).\nHer multidisciplinary research focuses on investigating archaea and their potential applications in biotechnology. She has an H-index of 21. She has authored one patent and has published more than 70 indexed papers and around 60 book chapters.\nShe has contributed to more than 150 national and international meetings during the last 15 years. Her research interests include archaea metabolism, enzymes purification and characterization, gene regulation, carotenoids and bioplastics production, antioxidant\ncompounds, waste water treatments, and brines bioremediation.\nRosa María’s other roles include editorial board member for several journals related\nto biochemistry, reviewer for more than 60 journals (biochemistry, molecular biology, biotechnology, chemistry and microbiology) and president of several organizing committees in international meetings related to the N-cycle or respiratory processes.",institutionString:null,institution:{name:"University of Alicante",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null,series:{id:"11",title:"Biochemistry",doi:"10.5772/intechopen.72877",issn:"2632-0983"},editorialBoard:[{id:"79367",title:"Dr.",name:"Ana Isabel",middleName:null,surname:"Flores",slug:"ana-isabel-flores",fullName:"Ana Isabel Flores",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRpIOQA0/Profile_Picture_1632418099564",institutionString:null,institution:{name:"Hospital Universitario 12 De Octubre",institutionURL:null,country:{name:"Spain"}}},{id:"328234",title:"Ph.D.",name:"Christian",middleName:null,surname:"Palavecino",slug:"christian-palavecino",fullName:"Christian Palavecino",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000030DhEhQAK/Profile_Picture_1628835318625",institutionString:null,institution:{name:"Central University of Chile",institutionURL:null,country:{name:"Chile"}}},{id:"186585",title:"Dr.",name:"Francisco Javier",middleName:null,surname:"Martin-Romero",slug:"francisco-javier-martin-romero",fullName:"Francisco Javier Martin-Romero",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSB3HQAW/Profile_Picture_1631258137641",institutionString:null,institution:{name:"University of Extremadura",institutionURL:null,country:{name:"Spain"}}}]},onlineFirstChapters:{paginationCount:14,paginationItems:[{id:"82103",title:"The Role of Endoplasmic Reticulum Stress and Its Regulation in the Progression of Neurological and Infectious Diseases",doi:"10.5772/intechopen.105543",signatures:"Mary Dover, Michael Kishek, Miranda Eddins, Naneeta Desar, Ketema Paul and Milan Fiala",slug:"the-role-of-endoplasmic-reticulum-stress-and-its-regulation-in-the-progression-of-neurological-and-i",totalDownloads:5,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Updates on Endoplasmic Reticulum",coverURL:"https://cdn.intechopen.com/books/images_new/11674.jpg",subseries:{id:"14",title:"Cell and Molecular Biology"}}},{id:"80954",title:"Ion Channels and Neurodegenerative Disease Aging Related",doi:"10.5772/intechopen.103074",signatures:"Marika Cordaro, Salvatore Cuzzocrea and Rosanna Di Paola",slug:"ion-channels-and-neurodegenerative-disease-aging-related",totalDownloads:6,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Ion Channels - From Basic Properties to Medical Treatment",coverURL:"https://cdn.intechopen.com/books/images_new/10838.jpg",subseries:{id:"14",title:"Cell and Molecular Biology"}}},{id:"81647",title:"Diabetes and Epigenetics",doi:"10.5772/intechopen.104653",signatures:"Rasha A. 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Thus proteomics, an area of research that detects all protein forms expressed in an organism, including splice isoforms and post-translational modifications, is more suitable than genomics for a comprehensive understanding of the biochemical processes that govern life. The most common proteomics applications are currently in the clinical field for the identification, in a variety of biological matrices, of biomarkers for diagnosis and therapeutic intervention of disorders. From the comparison of proteomic profiles of control and disease or different physiological states, which may emerge, changes in protein expression can provide new insights into the roles played by some proteins in human pathologies. Understanding how proteins function and interact with each other is another goal of proteomics that makes this approach even more intriguing. Specialized technology and expertise are required to assess the proteome of any biological sample. Currently, proteomics relies mainly on mass spectrometry (MS) combined with electrophoretic (1 or 2-DE-MS) and/or chromatographic techniques (LC-MS/MS). MS is an excellent tool that has gained popularity in proteomics because of its ability to gather a complex body of information such as cataloging protein expression, identifying protein modification sites, and defining protein interactions. The Proteomics topic aims to attract contributions on all aspects of MS-based proteomics that, by pushing the boundaries of MS capabilities, may address biological problems that have not been resolved yet.",annualVolume:11414,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/18.jpg",editor:{id:"200689",title:"Prof.",name:"Paolo",middleName:null,surname:"Iadarola",fullName:"Paolo Iadarola",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSCl8QAG/Profile_Picture_1623568118342",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorTwo:{id:"201414",title:"Dr.",name:"Simona",middleName:null,surname:"Viglio",fullName:"Simona Viglio",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRKDHQA4/Profile_Picture_1630402531487",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorThree:null,editorialBoard:[{id:"72288",title:"Dr.",name:"Arli Aditya",middleName:null,surname:"Parikesit",fullName:"Arli Aditya Parikesit",profilePictureURL:"https://mts.intechopen.com/storage/users/72288/images/system/72288.jpg",institutionString:null,institution:{name:"Indonesia International Institute for Life Sciences",institutionURL:null,country:{name:"Indonesia"}}},{id:"40928",title:"Dr.",name:"Cesar",middleName:null,surname:"Lopez-Camarillo",fullName:"Cesar Lopez-Camarillo",profilePictureURL:"https://mts.intechopen.com/storage/users/40928/images/3884_n.png",institutionString:null,institution:{name:"Universidad Autónoma de la Ciudad de México",institutionURL:null,country:{name:"Mexico"}}},{id:"81926",title:"Dr.",name:"Shymaa",middleName:null,surname:"Enany",fullName:"Shymaa Enany",profilePictureURL:"https://mts.intechopen.com/storage/users/81926/images/system/81926.png",institutionString:"Suez Canal University",institution:{name:"Suez Canal University",institutionURL:null,country:{name:"Egypt"}}}]}]}},libraryRecommendation:{success:null,errors:{},institutions:[]},route:{name:"chapter.detail",path:"/chapters/59364",hash:"",query:{},params:{id:"59364"},fullPath:"/chapters/59364",meta:{},from:{name:null,path:"/",hash:"",query:{},params:{},fullPath:"/",meta:{}}}},function(){var e;(e=document.currentScript||document.scripts[document.scripts.length-1]).parentNode.removeChild(e)}()