\\n\\n
More than half of the publishers listed alongside IntechOpen (18 out of 30) are Social Science and Humanities publishers. IntechOpen is an exception to this as a leader in not only Open Access content but Open Access content across all scientific disciplines, including Physical Sciences, Engineering and Technology, Health Sciences, Life Science, and Social Sciences and Humanities.
\\n\\nOur breakdown of titles published demonstrates this with 47% PET, 31% HS, 18% LS, and 4% SSH books published.
\\n\\n“Even though ItechOpen has shown the potential of sci-tech books using an OA approach,” other publishers “have shown little interest in OA books.”
\\n\\nAdditionally, each book published by IntechOpen contains original content and research findings.
\\n\\nWe are honored to be among such prestigious publishers and we hope to continue to spearhead that growth in our quest to promote Open Access as a true pioneer in OA book publishing.
\\n\\n\\n\\n
\\n"}]',published:!0,mainMedia:{caption:"IntechOpen Maintains",originalUrl:"/media/original/113"}},components:[{type:"htmlEditorComponent",content:'
Simba Information has released its Open Access Book Publishing 2020 - 2024 report and has again identified IntechOpen as the world’s largest Open Access book publisher by title count.
\n\nSimba Information is a leading provider for market intelligence and forecasts in the media and publishing industry. The report, published every year, provides an overview and financial outlook for the global professional e-book publishing market.
\n\nIntechOpen, De Gruyter, and Frontiers are the largest OA book publishers by title count, with IntechOpen coming in at first place with 5,101 OA books published, a good 1,782 titles ahead of the nearest competitor.
\n\nSince the first Open Access Book Publishing report published in 2016, IntechOpen has held the top stop each year.
\n\n\n\nMore than half of the publishers listed alongside IntechOpen (18 out of 30) are Social Science and Humanities publishers. IntechOpen is an exception to this as a leader in not only Open Access content but Open Access content across all scientific disciplines, including Physical Sciences, Engineering and Technology, Health Sciences, Life Science, and Social Sciences and Humanities.
\n\nOur breakdown of titles published demonstrates this with 47% PET, 31% HS, 18% LS, and 4% SSH books published.
\n\n“Even though ItechOpen has shown the potential of sci-tech books using an OA approach,” other publishers “have shown little interest in OA books.”
\n\nAdditionally, each book published by IntechOpen contains original content and research findings.
\n\nWe are honored to be among such prestigious publishers and we hope to continue to spearhead that growth in our quest to promote Open Access as a true pioneer in OA book publishing.
\n\n\n\n
\n'}],latestNews:[{slug:"intechopen-supports-asapbio-s-new-initiative-publish-your-reviews-20220729",title:"IntechOpen Supports ASAPbio’s New Initiative Publish Your Reviews"},{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"}]},book:{item:{type:"book",id:"9256",leadTitle:null,fullTitle:"Risk Management and Assessment",title:"Risk Management and Assessment",subtitle:null,reviewType:"peer-reviewed",abstract:"Risk analysis, risk evaluation and risk management are the three core areas in the process known as ‘Risk Assessment’. Risk assessment corresponds to the joint effort of identifying and analysing potential future events, and evaluating the acceptability of risk based on the risk analysis, while considering influencing factors. In short, risk assessment analyses what can go wrong, how likely it is to happen and, if it happens, what are the potential consequences. Since risk is a multi-disciplinary domain, this book gathers contributions covering a wide spectrum of topics with regard to their theoretical background and field of application. 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He is currently an Assistant Professor of the Institute of Geography and Spatial Planning and a member of the Modelling, Urban and Regional Planning, and Environmental Hazard and Risk Assessment and Management research groups of the Centre of Geographical Studies, University of Lisbon. . His field of expertise is geosimulation and geocomputation involving artificial neural networks, graphs theory, cellular automata, and multi-agent systems. Jorge’s works are quite diverse, focusing mainly on, but not only, in urban morphology, remote sensing, epidemiology, health geography, geomarketing, tourism, smart cities and big data.",institutionString:"University of Lisbon",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"5",totalChapterViews:"0",totalEditedBooks:"4",institution:{name:"University of Lisbon",institutionURL:null,country:{name:"Portugal"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:{id:"203745",title:"Dr.",name:"Sandra",middleName:null,surname:"Oliveira",slug:"sandra-oliveira",fullName:"Sandra Oliveira",profilePictureURL:"https://mts.intechopen.com/storage/users/203745/images/system/203745.jfif",biography:"Sandra Oliveira is a researcher for the Centre for Geographical Studies, in the Institute of Geography and Spatial Planning. She graduated in Geography from the University of Coimbra and has a MSc in Environmental Sciences from the University of Wollongong (Australia) and a Ph.D. in Forest and Natural Resources Engineering at the School of Agriculture of the University of Lisbon. She started as a Scientific Officer at the Joint Research Centre-EC in Italy, working in the European Forest Fire Information System (EFFIS). She works in environmental risk assessment and geographic information systems (GIS) and her main interests are in climatic risks, wildfires, forest protection and biodiversity. She is currently focused on spatial modelling and vulnerability assessment of vector-borne diseases.",institutionString:"University of Lisbon",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"2",totalChapterViews:"0",totalEditedBooks:"0",institution:{name:"University of Lisbon",institutionURL:null,country:{name:"Portugal"}}},coeditorTwo:{id:"304987",title:"Dr.",name:"César",middleName:null,surname:"Capinha",slug:"cesar-capinha",fullName:"César Capinha",profilePictureURL:"https://mts.intechopen.com/storage/users/304987/images/system/304987.jfif",biography:"César Capinha has a PhD in Environmental Sciences, a MSc in Geographic Information Systems and Territorial Modelling Applied to Planning, and a Degree in Geography. He is a Research Fellow at the Centre for Geographical Studies (Uni. of Lisbon). 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César is also very interested in the application and improvement of machine learning and statistical models for ecological modelling, particularly in predicting the risk of invasion by introduced species and in real-time modelling of ecological and epidemiological phenomena.",institutionString:"University of Lisbon",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"1",totalChapterViews:"0",totalEditedBooks:"0",institution:{name:"University of Lisbon",institutionURL:null,country:{name:"Portugal"}}},coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"272",title:"Management",slug:"management"}],chapters:[{id:"73125",title:"Introductory Chapter: Risk Management",doi:"10.5772/intechopen.93553",slug:"introductory-chapter-risk-management",totalDownloads:563,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:null,signatures:"Jorge Rocha, Sandra Oliveira and César Capinha",downloadPdfUrl:"/chapter/pdf-download/73125",previewPdfUrl:"/chapter/pdf-preview/73125",authors:[{id:"145918",title:"Ph.D.",name:"Jorge",surname:"Rocha",slug:"jorge-rocha",fullName:"Jorge Rocha"},{id:"203745",title:"Dr.",name:"Sandra",surname:"Oliveira",slug:"sandra-oliveira",fullName:"Sandra Oliveira"},{id:"304987",title:"Dr.",name:"César",surname:"Capinha",slug:"cesar-capinha",fullName:"César Capinha"}],corrections:null},{id:"73218",title:"Risk of Slipping Industrial Landfills",doi:"10.5772/intechopen.91020",slug:"risk-of-slipping-industrial-landfills",totalDownloads:346,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Due to the high rate of industrialization, urbanization and development of the road network, hydrotechnical constructions, etc., larger areas of agricultural and arable lands are affected, some of these being removed from the economic circuit. Due to the magnitude of the involved volumes, industrial waste has lately become a threat to all the components of the environment. In Romania, 90–95% of the total quantity of the produced industrial waste are stored, but only 24% of them have an environmental clearance certificate. The action of the climatic factors increases the risk of the occurrence of some landslides, which leads to the deterioration of the ecosystems and the risk of pollution, the loss of stability, the destruction of some historical objectives. Thus, the risk analyses represent the support for the decision-making process in taking solid measures, meant to lead to the limitation and diminution of the danger of slipping and losing the stability of these deposits. However, the implementation of the measures is based on a systemic model, supported by the concept of risk. This chapter presents the definition and classification of environmental risks, the risk assessment methodology and a risk analysis for waste in a mining area in Romania.",signatures:"Emilia-Cornelia Dunca and Sabina Irimie",downloadPdfUrl:"/chapter/pdf-download/73218",previewPdfUrl:"/chapter/pdf-preview/73218",authors:[{id:"307914",title:"Dr.",name:"Sabina",surname:"Irimie",slug:"sabina-irimie",fullName:"Sabina Irimie"},{id:"313179",title:"Dr.",name:"Emilia",surname:"Dunca",slug:"emilia-dunca",fullName:"Emilia Dunca"}],corrections:null},{id:"71351",title:"Supply Chain FMEA Risk Analysis for the Heavy Industry Sector",doi:"10.5772/intechopen.91042",slug:"supply-chain-fmea-risk-analysis-for-the-heavy-industry-sector",totalDownloads:805,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"The discussed problem is associated with the analysis of risk factors affecting supply chain management in the heavy industry sector based on the analysis of entities operating in this industry. 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During the research, potential design flaws and the effect of these flaws were identified, indicating the class, cause, and occurrence.",signatures:"Małgorzata Dendera-Gruszka and Ewa Kulińska",downloadPdfUrl:"/chapter/pdf-download/71351",previewPdfUrl:"/chapter/pdf-preview/71351",authors:[{id:"313072",title:"Prof.",name:"Ewa",surname:"Kulińska",slug:"ewa-kulinska",fullName:"Ewa Kulińska"},{id:"313373",title:"Ph.D.",name:"Małgorzata",surname:"Dendera-Gruszka",slug:"malgorzata-dendera-gruszka",fullName:"Małgorzata Dendera-Gruszka"}],corrections:null},{id:"70820",title:"Application of Quantum Physics Assumptions for Risk Assessment",doi:"10.5772/intechopen.90825",slug:"application-of-quantum-physics-assumptions-for-risk-assessment",totalDownloads:679,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Risk assessment is the result of assumptions of people performing it. Therefore, its use may be limited, because in principle it is difficult to predict events that we are not aware of. A certain solution to this problem seems to be the application of inception theory and quantum physics assumptions to describe future phenomena. The aim of the study will be to demonstrate the experience of risk assessment attempts using quantum physics assumptions. The current application of new assumptions for risk assessment in the case of road infrastructure allows for the thesis that a change in the approach to risk assessment is necessary in all areas related to human activity.",signatures:"Marek Rozycki",downloadPdfUrl:"/chapter/pdf-download/70820",previewPdfUrl:"/chapter/pdf-preview/70820",authors:[{id:"254855",title:"Mr.",name:"Marek",surname:"Rózycki",slug:"marek-rozycki",fullName:"Marek Rózycki"}],corrections:null},{id:"71133",title:"Risk Assessment Methodology in Public Financial Institutions",doi:"10.5772/intechopen.91152",slug:"risk-assessment-methodology-in-public-financial-institutions",totalDownloads:638,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"This chapter classifies the risk and fundamental elements necessary to manage it. It presents the individual stages of the procedure and standards of conduct in risk management. 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\r\n\tBoron is a chemical element with three valence electrons that can be considered as intermediate properties between metals and non-metals. Doping/integration of boron atom into other atoms provides new wonder materials such as Boron Nitride, Borophene, Boron Carbide, etc. with unique physical, chemical, and electrical properties. Based on the Scopus database, research on boron-based materials is still growing every year, from 3,099 documents in 2000 to 8,943 documents in 2021; the total number of papers exceeding 167,316. Therefore, boron-based materials have become one of the active and promising materials for many real-world applications.
\r\n\r\n\tThe main object of this book will focus on providing an overview of the research and developments of boron-based materials such as Boron Nitride, Borophene, Boron carbide, etc. The contents of this book will cover all aspects of boron-based materials including theoretical backgrounds of structure and properties, computer simulation, synthesis techniques, device fabrication, characterizations, and the current state-of-the-art applications.
\r\n\t
Whirl flutter instability is a specific type of aeroelastic flutter instability that may appear on turboprop aircraft. It accounts for the dynamic and aerodynamic effects of rotating parts, such as a gas turbine engine rotor or a propeller. The rotating mass increases the number of degrees of freedom and generates additional forces and moments. Rotating propellers also cause an aerodynamic interference effect between a propeller and the structure of a nacelle and a wing. Whirl flutter instability is driven by motion-induced unsteady aerodynamic propeller forces and moments acting on the propeller plane. It may cause unstable vibration, which can lead to failure of an engine installation or an entire wing.
\nThe propeller whirl flutter phenomenon was analytically discovered by Taylor and Browne [1]. The next pioneering work was performed by Ribner, who set the basic formulae for the aerodynamic derivatives of propeller forces and moments due to the motion and velocities in pitch and yaw in 1945 [2, 3]. After the accidents of two Lockheed L-188 C Electra II airliners in 1959 and 1960 [4], the importance of the whirl flutter phenomenon in practical applications was recognised.
\nThis chapter is focused on turboprop aircraft whirl flutter; however, it may also occur in tilt-rotor aircraft. The whirl flutter phenomenon relates the mutual interactions of the rotating propeller with the aircraft deformations and the aerodynamic forces emerging during forward flight.
\nThe principle of the whirl flutter phenomenon is outlined on a simple mechanical system with two degrees of freedom [5]. The propeller and hub are considered to be rigid. A flexible engine mounting is substituted with a system of two rotational springs (of stiffnesses
Two-degree-of-freedom gyroscopic system with a propeller.
Such a system has two independent mode shapes of yaw and pitch, with respective angular frequencies of
Independent engine pitch (a) and yaw (b) mode shapes.
Considering the propeller rotation with angular velocity
Backward (a) and forward (b) whirl modes.
The described gyroscopic motion causes the angles of attack of the propeller blades to change, which consequently leads to unsteady aerodynamic forces. These forces may, under specific conditions, induce whirl flutter instability. The most important terms regarding whirl flutter are yaw moment due to pitch
Stable (a) and unstable (b) states of gyroscopic vibrations for the backward mode.
The main problem in obtaining the analytical solution is to determine the aerodynamic force caused by the gyroscopic motion on each of the propeller blades. The presented equations of motion were set up for the system described in \nFigure 1\n by means of Lagrange’s approach. The kinematical scheme, including gyroscopic effects, is shown in \nFigure 5\n.
\nKinematical scheme of the gyroscopic system.
Three angles (
The angular velocities will be
\nConsidering that \n
The first part of Eq. (3) is independent of both
To describe the damping, we assume the structural damping commonly used in the flutter analyses, with the damping force proportional to the amplitude of the displacement:
\nThen, we obtain from Lagrange’s equations and Eqs. (3)–(5) a system of two mutually influencing differential equations:
\nGeneralized propeller forces and moments (see \nFigure 5\n) can be expressed as
\nThe index P means that the moment around the specific axis is at the plane of the propeller rotation. Employing the quasi-steady theory, the effective angles become
\nNeglecting the aerodynamic inertia terms (\n
where
The aerodynamic derivatives representing the derivatives of the two aerodynamic forces and two aerodynamic moments with respect to the pitch and yaw angles and to the pitch and yaw angular velocities are then defined as follows:
\nThese aerodynamic derivatives can be obtained analytically [2, 3, 6] or experimentally. Considering the symmetry, they can be expressed as follows:
\nNeglecting the low value derivatives, we can consider:
\nBy substituting Eq. (10) into the equations of motion (Eq. (6)) and considering the harmonic motion
\nwe obtain the final whirl flutter matrix equation
\nwhere the mass matrix becomes
\nthe structural damping matrix becomes
\nthe gyroscopic matrix becomes
\nthe structural stiffness matrix becomes
\nthe aerodynamic damping matrix becomes
\nand the aerodynamic stiffness matrix becomes
\n\nEquation (14) can be solved as an eigenvalue problem. The critical state emerges for a specific combination of the parameters
The influences of the main structural parameters are shown in the next figures. \nFigure 6\n shows the influence of the propeller advance ratio (
Influence of the propeller advance ratio on the stability of an undamped gyroscopic system.
Influence of the propeller hub distance ratio.
The described model, which is based on the assumption of a rigid propeller, is obviously applicable for standard turboprop aircraft (commuters, utility aircraft, and military trainers), for which the natural frequencies of the propeller blades are much higher than the frequencies of the engine system suspension vibrations. In large turboprops, in particular military transport aircraft with heavy multiblade propellers, the solution requires taking into account the deformations of the propeller blades as well [7, 8, 9, 10]. Obviously, whirl flutter investigation of tilt-rotor aircraft must include even more complex analytical models [11, 12].
\nThe analytically obtained results on the complicated physical principles of whirl flutter require experimental validation of the analytically obtained results, especially due to the unreliable analytical solution of the propeller aerodynamic forces. In addition, structural damping is a key parameter, to which whirl flutter is extremely sensitive and the characteristics of which need to be validated. Therefore, experiments using aeroelastic models are required.
\nMost of the developments in the whirl flutter experimental research were accomplished in the early 1960s. The experiments were carried out in direct connection with the Electras’ accidents. The first experimental investigations were accomplished by Houbolt and Reed [6]. They used the simple model of a propeller in the windmilling mode. The complex investigations of whirl flutter characteristics were conducted by Bland and Bennett [13]. The measurements, which were carried out in the NASA Langley wind tunnel were focused on the propeller forces and stability of the propeller-nacelle component model. As was typical, a propeller rotated in the windmilling mode. The experimental results showed that the theoretical aerodynamic derivatives underestimated the whirl flutter speed and the application of the experimentally obtained derivatives to the analytical solution made the solution much closer to the experimental results. The tilt-rotor concept was researched by Reed and Bennett [14], who focused on the flight regimes of high inflow angles. Apart from the rigid blades, they also accounted for blades’ flexibility when conducting the experiment on a simple model with flapping blades. Both backward and forward whirl mode instabilities occurred during the tests of the flapping-blade model. Similar experiments on the flapped blade rotor system were accomplished by Krishna Rao and Sundararajan [7] in NAL Bangalore. The influence of the blades’ flapping frequency on the whirl flutter stability for both backward and forward whirl modes was demonstrated by these experiments.
\nA more complex model, which represented an aircraft half-wing with an engine, was tested by Bland and Bennett [15] in NASA Langley. That model was a typical aeroelastic model with a duralumin spar and balsa segment structure. The main focus of these experiments was to investigate the influence of wing stiffness on whirl flutter.
\nThe largest experimental campaign was accomplished as a part of the response to the L-188 C Electra II aircraft accidents. Eventually, the tests helped to determine the cause of the accidents: whirl flutter. The aeroelastic model included four nacelles and four windmilling propellers. The model represented a full-span aircraft due to the investigation of the unsymmetrical phenomena. The model was flown in a wind tunnel with sufficient lift during the measurements and the trimmed flight was maintained by an operator controlling the horizontal stabilizer. Various configurations with reduced starboard outboard engine attachment stiffness were tested with the aim of identifying the causes of the aircraft accidents. The reduced stiffness parameters were also tested on the inboard power plant, and the combination of two engines was also tested. States with reduced damping were also tested. The experiments are summarised by Abbott et al. [16].
\nFurther experimental activities were primarily focused on the issues connected with the design and development of tilt-rotor aircraft, such as the Bell XV-3 or XV-15, Bell-Boeing V-22 Osprey, Agusta-Westland AW609, and XC-142A. A large investigation of the proprotor research model with flapping blades was conducted by Kvaternik and Kohn [17]. The stiffness of the nacelle attachment was reduced to reach the flutter boundaries within low velocities. The main aim of the work was the necessity to establish an experimental database for proprotor whirl flutter prediction with sufficient confidence. A total of 26 backward whirl flutter states and 50 forward whirl flutter states were found.
\nRecent experimental studies include the work performed by Rand and Peyran [18]. The tests were aimed at assessing the effects of the noted structural characteristics couplings on the whirl flutter of the proprotor during forward flight. In addition, the possibility of suppressing the instability by means of the active control of the wing’s structural characteristics was tested. The demonstrator included a proprotor in windmilling mode attached to the wing structure. A very simple table-top model was used by Acree et al. [19]. The model included weights in front of the leading edge of the blades’ tips. Moving the weights chordwise caused significant changes in the whirl mode stability.
\nA large model of the tilt-rotor aircraft concept, including a half-wing and proprotor, was tested for whirl flutter in the DNW wind tunnel in the Netherlands. The model was based on an aerodynamic wind tunnel model of a previous project. Therefore, aeroelastic scaling and modifications were limited. A multibody analysis based on available technical information was reported by Krueger [20].
\nExperimental activities that employed a model of a tilt-rotor aircraft component or a complete tilt-rotor aircraft model were performed on the WRATS aeroelastic demonstrator. The complete model was based on the 1/5-size semispan aeroelastic model of the V-22 Osprey aircraft. The model was used during the development of the Osprey to improve the stability characteristics of the aircraft. Later, the model was modified and utilized as the research demonstrator for active control research. WRATS-related activities are summarised by Piatak and Kvaternik et al. [21] and by Nixon et al. [22].
\nThe latest experimental activities were accomplished by Cecrdle et al. using the W-WING aeroelastic demonstrator [23]. The demonstrator was adapted from a half-wing with a span of 2.56 m with the engine of a former aeroelastic model of a commuter aircraft for 40 passengers. The total mass of the model is approximately 55.5 kg. The stiffness of the wing and aileron is modeled by a duralumin spar of variable cross-section. The aerodynamic shape is covered with modular balsa and plastic segments. The inertia characteristics are modeled by lead weights. The aileron actuation stiffness is modeled by means of a replaceable steel spiral spring. Optionally, the aileron may be actuated by the hydraulic actuator or by the electromagnetic shaker placed at the wing root via a push-pull rod. Furthermore, an active control system that is capable of simulating the additional mass, damping, or stiffness, including the nonlinear characteristics of these terms [24], may also be applied. The wing is fixed at the root to the pylon that is attached to the wind tunnel manipulator.
\nThe nacelle structure may be used either separately or attached to the wing structure as described. The influence of changes in the main parameters on the whirl flutter may be simulated by the demonstrator. The nacelle model includes two degrees of freedom (engine yaw and pitch). The engine attachment stiffness parameters are modeled using cross spring pivots. The leaf springs are changeable. The stiffness parameters can be adjusted independently by replacing the spring leaves. Both pivots are independently movable in the direction of the propeller axis. This allows for the adjustment of the pivot points of both vibration modes, while the overall length of the nacelle and the propeller position remain the same. The engine inertia parameters are modeled by a replaceable and movable weight. The weight is used to preserve position of the center of gravity in case the pivot stations change. Optionally, it also enables the position of the center of gravity to be changed. Provided the nacelle is attached to the wing, the wing dynamic characteristics can also be adjusted to evaluate the influence of the wing structure on the whirl flutter. The design solution of the engine attachment is shown in \nFigure 8\n.
\nDesign solution of W-WING demonstrator engine attachment, motor, and propeller.
Sensor instrumentation of the wing includes strain gauges in the root and half-span sections that are configured to measure the torsional, vertical bending, and in-plane bending deformations. In addition, the demonstrator is equipped with accelerometers at the front of the engine and at the wing-tip section. Accelerometers measure the vertical and lateral acceleration.
\nThe gyroscopic effect is simulated by the rotating mass of the propeller blades. Actually, two sets of blades are available (light, made of duralumin, and heavy, made of steel). The propeller of 0.7 m diameter represents a scaled-down real 5-blade propeller. The propeller is powered by an electric motor and it can operate at arbitrary revolutions of up to 3000 rpm. Obviously, the windmilling mode is also applicable. The propeller blades are adjustable at a standstill. There are several blade adjustment options (angles of attack) that are applicable for specific ranges of the flow velocity. Additionally, the blade angle of attack may be used to manage the revolutions of the windmilling propeller.
\nThe tests were performed in the VZLU 3-m-diameter low-speed wind tunnel. To prevent the induced effects at the wing root region, the wing is combined with the splitter plate. The demonstrator is fixed to the attachment arm inside the wind tunnel test section. Both the angle of attack and angle of sideslip of the tested model may be changed, provided if requested. The test arrangement is shown in \nFigure 9\n.
\nW-WING demonstrator in the wind tunnel test section.
The measurement variants of the model were defined by the following structural parameters: pitch and yaw attachment stiffness, pitch and yaw hinge station, mass-balance weight station, choice of propeller (duralumin or steel blades), and finally, the propeller blade’s 75%-section angle of attack (α).
\nThe tests were focused on the variation of the pitch and yaw stiffness first. During these tests, the most promising variants with respect to the pitch and yaw stiffness, which showed the largest vibrations, were found and used as the baselines during the next phase of the tests. Then, the variations of the blade angle of attack, choice of a light or heavy propeller, and variation of the pitch hinge station and mass-balance weight station were examined. The measurements included excitation by the flow turbulence and by the aileron flapping sweep. The latter was found as very useful for the estimation of whirl mode damping.
\nThe next figures show examples of the experimental results. The figures show evaluated whirl mode parameters as functions of the windflow speed. These parameters are propeller revolutions, damping, and frequency of the whirl mode and the maximal amplitude (pitch or yaw) of the front engine sensor section. The first example (\nFigure 10\n) demonstrates a very stable case. The vibration amplitude of the structure is very low and the damping increases with the windflow velocity.
\nWhirl mode parameters: (a) propeller rpm, (b) whirl mode frequency, (c) whirl mode damping, (d) yaw or pitch amplitude. Stable case (pitch spring: nr.2, yaw spring: nr.2, pitch hinge: middle, weight: rear, blades: heavy, α = 2.5°).
The next example (\nFigure 11\n) shows the case in which the instability was reached. The amplitude curve shows a rapid increase near the flutter velocity. Additionally, the damping reaches zero. The damping curve represents the damping values given by operational modal analysis (OMA). These damping values, which were obtained by the evaluation of the logarithmic decrement, are very small negative values, which are not noticeable in the figure. A negative damping value represents an unstable state. The unstable states with higher negative damping could not be reached due to safety reasons.
\nWhirl mode parameters: (a) propeller rpm, (b) whirl mode frequency, (c) whirl mode damping, (d) yaw or pitch amplitude. Unstable case (pitch spring: nr.2, yaw spring: nr.2, pitch hinge: middle, weight: front, blades: light, α = 0°).
\n\nFigures 12\n and \n13\n show more detailed information regarding the influence of the parameters. The influence of the pitch hinge station is demonstrated in \nFigure 12\n. Moving the hinge rearward increases the a/R ratio, and therefore, has a positive effect on flutter stability. The influence of the mass-balance weight station is demonstrated in \nFigure 13\n. Moving the weight rearward causes a decrease in mass moments of inertia (JY and JZ) and the related increase in the yaw and pitch frequency (fΨ and fΘ), and therefore, it also has a positive effect on flutter stability. Flutter speeds of configurations with heavy blades are lower compared to the flutter speeds with light blades as the heavy blades reduce both the yaw and pitch frequencies (fΨ and fΘ).
\nInfluence of pitch hinge station (LΘ) on flutter speed (25% = rear; 46% = middle; L = light blades; H = heavy blades; LW = mass-balance weight station).
Influence of mass balance weight station (LW) on flutter speed (0% = front; 100% = rear; L = light blades; H = heavy blades), rear (25%), and middle (46%) pitch hinge stations.
The airworthiness regulation standard requirements for dealing with the aeroelasticity and flutter also include requirements related to the whirl flutter. Essentially, the whirl flutter requirements are applicable only to aircraft powered by a turboprop power plant system. In the following text, the requirements of the FAR/CS 23 regulation standard, which is applicable to smaller turboprop aircraft, are taken into consideration. The whirl flutter related requirement, which is included in §629(e), is applicable regardless of the aircraft configuration or the number of engines (twin wing-mounted, single nose-mounted, twin fuselage mounted pusher, etc.). §629(e)(1) includes the main requirement to evidence the stability within the required V-H envelope, while §629(e)(2) requires the variation of structural parameters such as the stiffness and damping of the power plant attachment. The whirl flutter analysis must, therefore, include all significant aircraft configurations with respect to fuel and payload that are applicable to the aircraft operation. The whirl flutter analysis must also include the influence of the variance of the power plant mount structural parameters when simulating the possible changes due to structural damage (e.g., deterioration of engine mount isolators). Note that further requirements that are applicable to aircraft compliance with the fail-safe criteria come from §629(g).
\nWe can use two main approaches for the analysis:
\nFirst is the standard approach, in which the analyses are performed for a known set of structural parameters, and the results are whirl flutter stability characteristics (e.g., whirl flutter speed). The resulting flutter speed is then compared to the certification velocity according to the flight envelope. The analyses are performed sequentially, state by state.
\nThe standard approach is good for complying with the main requirement (§629(e)(1)), which is realized by evaluation of the nominal parameter states. \nFigure 14\n shows an example of a V-g-f diagram of such a calculation. No flutter instability is indicated up to the certification velocity, which is 191.4 m/s in the case, and therefore, the regulation requirement is fulfilled. Calculations are performed for all applicable mass configurations. However, for parametric studies that may include huge numbers of analyses, such an approach may become ineffective unless some tool for automated analysis, data handling, and processing is used. However, the applicability of such automatic processing systems is always limited.
\nExample of whirl flutter calculation (V-g-f) diagram, (a) damping, (b) frequency, nominal state.
Therefore, to comply with the parameter variation requirement (§629(e)(2)), the second, optimization-based approach [25] can be used. In this approach, the flutter speed is set equal to the certification speed, and the results are critical values of the structural parameters. The stability margin can then be obtained from these critical structural parameters. The analyzed states are then compared only with respect to the structural parameters and the relationship to the stability margin. Such an approach can save large amounts of time because the number of required whirl flutter analyses is dramatically reduced.
\nProvided a full-span model is considered, four design variables are defined: (1) effective stiffness of the engine attachment for symmetric pitch, (2) effective stiffness of the engine attachment for antisymmetric pitch, (3) effective stiffness of the engine attachment for symmetric yaw, and (4) effective stiffness of the engine attachment for antisymmetric yaw. The solution includes three frequency ratio constraints: (1) for symmetric engine vibration frequencies, (2) for antisymmetric engine vibration frequencies, and (3) for critical whirl flutter frequencies. Additionally, the flutter constraint, i.e., the requirement of flutter stability, is applied for the certification speed. The objective function is then formally expressed as the minimization of the sum of engine vibration frequencies. \nFigure 15\n shows an example of a V-g-f diagram for the optimization-based calculation. There is a flutter state of mode nr.2 (engine pitch vibration mode) at the velocity of 191.4 m/s representing the whirl flutter instability. Calculations are performed for several values of the critical frequency ratio to construct a stability margin curve, which is then constructed for all applicable mass configurations, as shown in the example in \nFigure 16\n. Stability margins may be constructed with respect to either engine yaw and pitch vibration frequency or engine yaw and pitch attachment effective stiffness. The former type of margin is then compared with the engine vibration frequencies, obtained by the GVT or analytically, to evaluate the rate of reserve. \nFigure 17\n demonstrates an example of such an evaluation. The dashed line represents the (±) 30% variance margin in engine attachment stiffness. Another parameter to be evaluated is the damping. This is provided by calculation with very low structural damping, represented by the damping of
Example of whirl flutter calculation (V-g-f) diagram, (a) damping, (b) frequency, optimization-based calculation.
Example of whirl flutter stability margins for multiple mass configurations.
Example of whirl flutter stability margin evaluation.
As obvious from \nFigure 17\n, there is sufficient reserve in stability of the nominal state with respect to the stability margin, and therefore, the regulation requirements would are fulfilled.
\nThe presented chapter addresses a specific aeroelastic phenomenon that is applicable for turboprop aircraft structures: whirl flutter. This chapter includes basic facts regarding the physical principles and the analytical solution of the described phenomenon. After that, the experimental research activities are outlined, with a focus on the recent experiments on the W-WING whirl flutter demonstrator. Finally, the approaches to aircraft certification are explained. Comprehensive information on the whirl flutter phenomenon from all aspects can be found in Ref. [26].
\nThis work was supported by the institutional support of nonprofit research organisations by the Ministry of Industry and Trade of the Czech Republic.
\nGrowing demand for energy in all possible forms (mobility, heat, electricity) induced intensive research on various energy harvesting and storage systems. Today, it is clear that fossil fuels are no longer a reasonable choice for further society development. Various reasons, such as environmental pollution, depletion of natural resources, and remarkable climate changes, stimulated intensive research on sustainable solutions for energy harvesting and storage. In this context, numerous technologies are known for sourcing the energy in a “green” manner (like photovoltaics, wind turbines, flywheels); however, this energy must be somehow stored to be further used when needed.
Electrochemical energy conversion and storage systems are one of the most common solutions used every day by almost everyone—at home, at work, or in the car. This is true that well-known Li-ion batteries allowed the world “to move” and made our lives more “mobile”. Nevertheless, these are not the only ones that have been recently developed and used. Despite the high amount of energy stored in batteries, their power density is still not enough to eliminate other technologies. Furthermore, their typical redox-based charge storage mechanism makes their lifetime short (counted in thousands of cycles) and thus less resource-effective. Electrochemical capacitors, with their high-power density and moderate energy, cyclability counted very often in millions of cycles and much safer chemistry in the cell, appear to be an interesting technology that could serve as a standalone system or greatly accompany the battery.
Conventional capacitors are composed of two flat, non-porous plates (electrodes) separated by a dielectric material. These devices are characterized by low energy density, limiting their application [1]. In 1957, a new group of capacitors, called electrochemical capacitors (ECs), super- or ultracapacitors, emerged. It must be here pointed out that only the “electrochemical capacitor” term should be used for scientific purposes, as other names (supercapacitors, ultracapacitors, etc.) refer to commercial products. Furthermore, “electrochemical capacitors” are often confused with “electric double-layer capacitors (EDLCs)”. In fact, EDLCs are always ECs; however, this term is reserved only for the systems exploiting the double-layer charging/discharging process, thus, the mechanism is entirely electrostatic, while ECs could also exploit redox-based processes in the charge storage (like hybrid systems).
Unlike conventional capacitors, in ECs, the electrodes of highly developed surfaces are used. Such electrodes allow higher capacitance to be reached and, in consequence, the energy accumulated increases while their superior power is maintained [2].
It is worth noting that besides ECs, there are many energy storage devices and their application depends on the performance parameters. Therefore, these properties, i.e., energy and power, are crucial from a practical point of view. The so-called Ragone plot (Figure 1) is the best way to compare various systems’ performance [4].
Ragone plot presenting the performance parameters (energy and power) of different energy storage/conversion devices [
It can be noticed that the electrochemical capacitors demonstrate the properties between conventional capacitors and batteries—the specific power is very high, however, slightly lower than in the case of “dielectric” capacitors, and the specific energy is significantly higher—but still moderate if compared with the batteries (especially commonly used Ni/MH, Li-ion and Li-primary ones). Besides the tremendous power of ECs that allows them to be charged and discharged very quickly, these devices are getting more and more attention because of their long lifetime and safe/reliable use [5]. For these reasons, ECs are applied in the automotive industry—for instance, in regenerative braking, start-stop systems, or track control devices. Nonetheless, the energy density of these devices needs to be increased, as the volume or weight of the device must be reduced.
As already mentioned, ECs consist of two porous electrodes of highly developed surface area. The electrodes are very often made of carbon materials (especially activated carbons) due to their good conductive properties, high availability (abundance) as well as relatively low price [6]. During the ECs operation, the electrodes are polarized positively (+) and negatively (−). An insulator separates them to prevent short circuits. These components are immersed in an electrolyte, playing the role of ion source and carrier (Figure 2a). When charging the cell, positively charged ions (cations) are adsorbed on the (−) electrode surface, while negatively charged ions (anions) are adsorbed on the (+) electrode surface. An electrical double-layer is formed at the electrode/electrolyte interface during this process. For this reason, ECs are also called electric double-layer capacitors—EDLCs (Figure 2b
Carbon materials can be enriched with surface functional groups, heteroatoms like oxygen or nitrogen, and transition metal oxides like MnO2. Moreover, carbon/electrically conductive polymer (e.g., PANI, PPy, PEDOT) composites can be synthesized and used as electrodes for ECs. These materials are classified as pseudocapacitive ones [9]. The charge storage mechanism in such devices can be described as quick, continuous faradaic reactions occurring with no phase change in the electrode material. The cells operating with these materials are very often called asymmetric or pseudocapacitance-based ECs (Figure 2b). One should restrain from using the “pseudocapacitor” term, as the pseudocapacitance concerns the electrode, not the system. If redox reactions occur on both electrodes, the system should rather be considered as a battery.
ECs incorporating pseudocapacitive materials may suffer from shorter cycle life, due to unstable behavior of the functional groups during long-term tests and chemical and mechanical composites degradation. Moreover, the cost of such materials exceeds the cost of non-modified activated carbon and impacts the final price of the cell. Thus, another solution was proposed to increase the capacitance, causing an increase in the energy of the ECs—i.e., electrolytes demonstrating redox activity (redox ECs, Figure 2b).
Generally, the redox processes in the batteries are attributed to the electrode material, ensuring high charge storage capacity. However, solid-state diffusion remarkably impacts the power capability. Shifting the redox processes to electrolytic solution remarkably diminishes the mass-transfer limitations and allows the power of electrostatic interactions to be almost maintained.
Electrochemical capacitor: (a) construction, (b) types and (c) principle of operation.
The operating potentials of each electrode in symmetric EDLCs are comparable. For instance, when ECs are investigated with cyclic voltammetry, the curves of rectangular shape are recorded (Figure 3; solid lines), since the capacitance does not depend on the potential.
Comparison of the voltammetric responses of a positively (+) and negatively (−) polarized electrode of the electric double-layer capacitor (solid line) and a redox (hybrid) capacitor (dashed line) [
In the case of galvanostatic charge/discharge, the curves are triangular [11]. Obviously, it is possible to notice potential shifts (very often negligible) that originate from matching cations/anions with the pore diameter of the electrode material. The capacitance of the system (Ccell) can be calculated based on Eq. (1) because two electrodes that store the energy at the electrode/electrolyte interface are considered as two capacitors in series [10].
Assuming the capacitance values of both electrodes in symmetric cell are comparable (
The specific energy for the EDLCs (
where
For accurate calculations, it is necessary to consider the ohmic drop for Δ
In the case of ECs operating in redox-active electrolytes, the potential range of each electrode can significantly differ, as presented in Figure 3 (dashed lines). It is seen that one electrode demonstrates capacitive character, typical of EDL formation, with constant capacitive current recorded; at the same time, the positive electrode demonstrates a very high current response with a narrow potential range. This suggests high capacity, accumulated in a narrow potential range, typical of the redox process. In the galvanostatic charge/discharge technique, the redox activity is seen as a
For the cells’ performance characterization, the specific energy (
Power capability needs to be calculated as well for the full characterization of the investigated cells. It is directly related to the system’s energy, according to Eq. (6):
where Δ
For more detailed information and characterization techniques, comprehensive literature reports are published [9, 12, 13].
It must be clearly stated that the energy and power of the devices should be expressed per mass of the cell components and must not be calculated for the single electrode. However, on the laboratory scale, when the electrolyte is in great excess, only the mass of the electrolyte confined in the pores should be considered. The other possibility is to normalize these values per volume of the device’s components. All the presented methods of cells characterization is correct, but the author needs to comment on how the calculations were made [10, 11, 12].
As mentioned, the redox-active electrolyte in EC allows the cell performance to be significantly improved. It is necessary to use the electrodes made of electrically conductive material to make the electron flow from the electrode to the electrolyte possible [14, 15, 16, 17].
There are many redox couples with well-defined and stable redox activity that can be used as additives for electrolytic solutions. The most popular ones, with their reduction potentials (expressed
Redox couples with their reduction potentials [
Depending on the cell construction, electrode material used, potential application, and expected operating performance, one can select which redox couple is suitable for EC that meets the requirements. In the case of aqueous-based systems, there are additional issues that need to be taken into account. First of all, at too high or too low potentials, water is decomposed, so oxygen and hydrogen evolution can be observed, respectively. These reactions are considered harmful for the cell because (i) the solvent should not be decomposed, (ii) evolving gases can block the electrode porosity, (iii) the highly active oxygen causes the irreversible electrode oxidation and its degradation, and (iv) corrosion of the current collectors remarkably affects the cell lifetime. Therefore, the potential of the chosen redox couple should preferably be between hydrogen (HEP) and oxygen (OEP) evolution potential.
The second issue is related to the electrolyte pH. Both HEP and OEP are pH-dependent—when the solution pH increases, these potentials are shifted toward lower potentials [19]. It is, thus, possible to slightly adjust the HEP and OEP by regulating the electrolyte pH. However, one should keep in mind that the potentials of some redox couples are also pH-dependent, so with the pH change, their potential will also change. Moreover, the stability of redox couples also depends on the solution pH.
Redox-active electrolytes are grouped in a way similar to the types of electrolytes. Hence, they can be divided into two main groups—aqueous and nonaqueous ones [11, 20].
Aqueous solutions, despite their limited operating voltage related to the theoretical water decomposition above 1.23 V, are very attractive electrolytes for ECs due to their price lower than for nonaqueous electrolytes and the possibility of the cell manufacturing in an ambient atmosphere. Moreover, the impact of water-based solutions on the environment is rather negligible. These solutions are also characterized by high conductivity and low viscosity. The main drawback of the ECs operating in redox-active electrolytes is moderate cycle life related to the efficiency of the redox reactions and possible side reactions [21, 22].
In general, it seems beneficial to combine more than one redox additive in one electrolyte. If the ratio between different redox species is well-optimized, the energy reached in such cells is higher than reported for the single redox couple [23, 24].
Aqueous redox-active electrolytes can be divided into three groups: cationic, anionic, and neutral electrolytes, due to the charge of the redox-active ion. It is worth mentioning that the redox ions in cationic and anionic electrolytes contribute to the EDL formation, whereas in neutral electrolytes redox species quite often do not participate in this process [11].
Cationic redox electrolytes can be divided into three groups: lanthanides, transition metals, and organic species [18, 25, 26, 27, 28, 29, 30, 31]. The general requirement is that the solubility of these species should be possibly high and their standard potential should be close to HEP, as their activity is expected at the negative electrode [18].
Cerium, which belongs to lanthanides, was introduced to the acidic solution [11, 27]. However, standard redox potentials of lanthanides (∼+1.6 V vs. NHE of Ce3+/Ce4+ redox couple) being higher than OEP definitely limits their application.
The second group—transition metals like Zn, Sn, Mn, Fe, Ni, Cu, include a solid phase in the solution of neutral or acidic pH. The cations are reduced at relatively low potential, between −0.762 V and +0.337 V vs. NHE. However, still irreversible hydrogen evolution reaction can occur during the metal electrodeposition in aqueous solutions. Although in general hydrogen evolution reaction is considered parasitic or unwanted, it is possible to store hydrogen reversibly in the electrode porosity—it is necessary to use microporous electrodes for this purpose. Moreover, the addition of halide ions to the electrolytic solution can be beneficial—halide anions will block the carbon and its active sites preventing hydrogen reactions [32, 33]. Finally, metal electrodeposited on the electrode can affect the specific surface area of the electrode and worsen the performance stability of the system. It is also possible to avoid solid-state metal deposition on the electrode, by applying redox couples dissolved in the liquid state, like Fe2+/Fe3+, Cu+/Cu2+ [26, 34].
Viologen di-cations can be included in the organic cationic additives. Moreover, these species are characterized by fast redox kinetics and high reversibility [35, 36]. It was found that 1,10-dimethyl-4,40-bipyridinium cation (MV2+) is strongly attracted to the electrode surface. However, after reduction to MV+, the physical interaction between these species and the electrode can be even stronger [37]. This may be beneficial to reduce self-discharge, which is caused by redox shuttling.
As the cations are supposed to be attracted to the negatively polarized electrode, redox reactions originating from cationic additives are mostly at the negative side. However, the synthesis of carbon material exhibiting the affinity to cations and application of such an electrode as the positive one in ECs is also reported [26, 38, 39, 40]. It is worth noting that not only carbon materials can be functionalized—in fact, but various polymers can also be enriched with cationic (or anionic) functional groups.
The systems operating in redox-active electrolytes with transition metals as active species need to be assembled with ion-selective membranes as separators. These membranes can mitigate the self-discharge and leakage current which are relatively high for such systems [23, 39]. Nevertheless, the application of viologens (organic molecules) as a redox additive to the electrolytic solution can also decrease self-discharge without the necessity of ion-selective membrane employment. It is caused by viologens strong adsorption at the porous electrode surface [18, 28].
The main disadvantage of using viologens is their limited solubility and large size of the molecule that can negatively influence the ECs performance [32, 41], especially because of mass-transport issues.
The anionic redox-active electrolytes contain halides (iodide [14, 42, 43, 44], bromide [4, 45], pseudohalides (thiocyanate [41], selenocyanate [46]), organometallic complexes (ferricyanide and, ferrocyanide [21, 47, 48, 49, 50, 51, 52, 53]) and organic anion—like indigo carmine [54].
In the case of halide and pseudohalides-based electrolytes, a well-defined redox response is recorded at the positively polarized electrode. They are characterized by strong adsorption at the electrode surface. Hence, the self-discharge of the cell operating in such electrolytes is relatively low and the application of an ion-selective membrane is not needed. Moreover, halides can be coupled with metal ions deposition reaction, especially Zn/Zn2+, and viologen redox couple [30, 31, 55], however, such systems are no longer typical capacitors. To avoid metal dendrites formation, some additional components should be used, like dendrite suppression or nanoporous separators [56, 57, 58, 59].
The standard potentials of bromide and iodide reactions are similar; however, the bromides demonstrate slightly higher values [60]. It can be beneficial for reaching higher energy of the ECs, as the operating voltage might be shifted toward higher values. Nonetheless, bromide solutions are toxic, so for safety, it is favorable to use iodide-based solutions. Also due to the high standard potential of Br−/Br2, close to oxygen evolution potential, the electrolyte decomposition can be difficult to control and corrosion on current collectors can be observed [31]. Iodide-based ECs are widely described in the literature. These systems are characterized by stable operation even during long-term experiments [32, 61, 62].
Pseudohalides solutions exhibit similar electrochemical behavior to halide solutions when used as electrolytes in ECs but self-discharge is definitely more pronounced. Thiocyanates-based solutions are especially interesting for ECs application due to their higher maximum operating voltage than selenocyanate-based electrolytes. Moreover, the energy and power of such systems are comparable to those reached in iodide-based electrolytes, but their lifespan is still limited [41].
Organometallic-based electrolytes (ferricyanide- or ferrocyanide-based solutions) ensure the promising performance of the ECs. The main drawback of these electrolytes is high self-discharge, seen as low efficiency, especially at low current loads. Therefore, ion-selective membranes are very often used to limit redox shuttling [48, 63].
Even in aqueous-based systems, organic redox-active additives can be used. For instance, hydroquinone (HQ), anthraquinone [64, 65, 66], catechol (an isomer of benzoquinone), rutin [67], p-phenylenediamine [68], and conducting polymers [69, 70] (if soluble in water) are popular neutral electroactive species added to the electrolytic solutions. To enable redox reaction with proton transfer, the use of supporting electrolytes is necessary. For this reason, acid solutions (H2SO4) are used as a source of protons. As a consequence, the maximum operating voltage of the ECs operating in an acidic medium is limited to ∼1 V, and, because of corrosion issues, the use of gold or other noble metal current collectors is necessary.
As the representative reaction, the reduction of benzoquinone to hydroquinone (Q/HQ) is presented in Eq. (7).
Moreover, the conductivity of the electrolytic solutions with organic molecules can be diminished. Therefore, additional ionic species are very often introduced (like neutral salts—KNO3 or alkaline KOH [71]); hence, the formation of EDL can be more efficient. These systems are also characterized by considerable self-discharge related to the movement of neutral molecules between the polarized electrodes. To reduce self-discharge and increase the efficiency of the charging and discharging processes, the use of an expensive proton exchange membrane is recommended, which significantly increases the price of ECs [72]. The cells operating in the electrolytes with polymeric additives (i.e., sulfonated polyaniline or p-nitroaniline) also required the use of cheaper membranes. It is possible to use a semipermeable membrane that allows the movement of protons and supporting ions like SO42−. The drawback of such electrolytes is the solubility of the polymeric molecules—when the concentration of electroactive molecules is relatively low, the capacity of the cell is also limited [69]. Therefore, it is necessary to investigate the ECs with new polymer-based electrolytes to develop these systems and reach satisfactory operating parameters.
As cationic additives exhibit redox activity at the negatively polarized electrode and anionic additives at the positively polarized one, they can be combined, giving significant performance improvement. These redox couples should be carefully selected because they must be stable and soluble under the same conditions. Otherwise, it would be necessary to use more expensive separators/membranes and the assembly process would be more complex [18]. ECs operating in the electrolyte containing viologen cation and halide anion were tested. In the case of the electrolyte with MV2+ and I− redox-active species during cell charging, an irreversible capacitance loss was noticed. It was caused by precipitate formation (MX•+–I−) [73]. When the iodide was replaced by bromide (the anion of higher standard potential) the processes were reversible, and higher energy was reached. However, because of the high potential needed for Br−/Br3− activity, the signs of corrosion were observed. MVCl2/KBr-based cells suffer from a relatively high self-discharge, which was more pronounced than for halide-based electrolytes, suggesting that MV species are, mostly, responsible for this voltage loss. Therefore, other viologen was used—1,10-diheptyl-4,40-bipyridinium dibromide (HVBr2), resulting in lower self-discharge. Probably, not only stronger adsorption of HV2+ cation was the reason for the lower self-discharge but also these cations were immobilized due to the precipitate formation within the carbon electrode [74]. The optimization of redox-active species concentration, choice of the appropriate counter anion/cation for redox-active cation/anion, respectively, and experimental conditions optimization is definitely more complex and time-consuming than for one active component within the electrolytic solution. However, taking into account the significant improvement of the energy stored in the EC operating in the redox-active electrolytes, it is still worth discovering the potential of this field.
Commercially used ECs very often employ nonaqueous electrolytes (organic ones) despite the fact, that they cannot be considered environmentally friendly solutions, because of the necessity of toxic solvents use—like acetonitrile or propylene carbonate. However, they have a few advantages that make them more attractive for ECs construction: wider electrochemical window (up to 3.8 V [75, 76]) which allows higher energy to be stored, and long cycle life. On the other hand, there are ionic liquids called “green solutions”, that can be also used in ECs but they are relatively expensive.
In the organic electrolytes, conductive salts like tetraethylammonium tetrafluoroborate (TEABF4), lithium bis(trifluoromethanesulfonyl)imide (LiTFSI), 1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide (EMImTFSI), lithium hexafluorophosphate (LiPF6), are dissolved in acetonitrile (ACN) or propylene carbonate (PC), which are the most popular solvents for ECs application [22, 77, 78, 79, 80, 81]. As already mentioned, organic electrolytes allow the ECs to operate at higher voltages than aqueous-based electrolytes do [82] and they provide higher power than the systems with ionic liquid (IL) electrolytes [11, 83] due to the higher ionic conductivity of organic electrolytes.
The maximum voltage of reported organic-based cells is 2.5 V, when IL (1-ethyl-3-methylimidazolium ferrocenylsulfonyl-(trifluoromethylsulfonyl)-imide, [EMIm][FcNTf]) in ACN [76] and p-phenylenediamine additive to lithium perchlorate LiClO4 in ACN [84] were used as electrolytes. The mixture of microporous carbon with carbon black and graphite was used as the electrode material. However, there are also other materials that can be used, for instance two-dimensional titanium carbide (MXene) [81].
Organic electrolytes exhibiting redox activity are not as popular as aqueous electrolytes. Therefore, there is a gap in this field of study as there are many possible redox additives that could be employed for organic electrolytes [85].
Ionic liquids (ILs) are compounds composed entirely of ions—bulky, usually asymmetric organic cation and anion (weakly coordinating) that can be both organic and inorganic [86, 87]. As they are ionic conductive, there is no need to use additional solvents. They are characterized by high electrochemical stability, ensuring a high voltage window (>3 V) and high thermal stability [88, 89]. It is possible to introduce redox additives to IL, for example by incorporating metal ions (Cu2+ added in the form of copper chloride to [EMIm][BF4] [40], neutral redox molecules [90, 91] (HQ added to [TEA][TFSI] [92]) or sulfates (SnSO4 and VOSO4 [23]).
However, ILs themselves can also exhibit redox activity if an anion of IL is electroactive. Hence, such an electrolyte can be called redox-active IL. To observe effective and beneficial redox contribution to ECs charge/discharge, a high concentration of electroactive species needs to be ensured. Electrolyte composed of two ILs—[EMIm][BF4] and [EMIm]Br, where the latter one is a redox additive (1 mol L−1) to the former one, was used in microporous electrodes-based EC. The operating parameters were significantly improved due to the bromide activity (the specific energy was almost twice higher if compared to the [EMIm]BF4-based system, where only EDL formation is assumed, and the Coulombic efficiency was ∼100%) [83]. Moreover, the leakage current was reduced, probably due to strong adsorption of halide on the positively charged carbon electrode, described for aqueous-based cells [18, 32].
Biredox ILs can also be used as electrolytes for ECs. The idea arises due to the potential balancing issue when additives, like metal ions, HQ, or redox-active anions, are introduced to the system operating with microporous carbon electrodes [75]. The cation of IL ([BMIm][TFSI]) was functionalized with AQ, whereas the anion was functionalized with 2,2,6,6-tetramethylpiperidinyl-1-oxyl (TEMPO) molecule. The energy density of such a system was definitely higher than for IL with redox additive as an electrolyte but the specific power and lifetime were rather moderate.
The application of redox-active IL as electrolytes in ECs is a promising strategy to increase the specific energy of the systems. However, one should take into account that the price of such devices is relatively high. Moreover, the power performance and the lifespan of the ECs operating in ILs should be improved.
Gels are characterized by very good stability (both chemical and mechanical) and they can be made of eco-friendly materials [93]. They can be successfully applied as electrolytes (based on aqueous solutions or ILs) for ECs [61, 94, 95]. Gel electrolytes were introduced to ECs to reduce their self-discharge [96] and enable the development of flexible devices, where liquid electrolytes would expose the cells to leaks. Redox mediators can be introduced to the gel electrolytes and increase both ionic conductivity and capacitance of the ECs [97]. For instance, when indigo carmine was added to the gel electrolyte based on polyvinyl alcohol (PVA) and sulfuric acid, the ionic conductivity increased by almost 190% [98]. Moreover, the lifetime of the devices can be prolonged. Redox-active compounds, like 1-butyl-3-methylimidazolium iodide and bromide (BMImI, BMImBr) [99, 100], 1-anthraquinone sulfonic acid sodium [101], 1,4-naphthoquinone [102], including indigo carmine [98] and FeBr3 [103], can be incorporated into gel structure. BMImBr with Li2SO4 as an additive to the PVA-based gel electrolyte was reported as a perfect solution for lowering self-discharge, increasing energy, and lifetime of the EC [100]. Flexible capacitors based on gel electrolyte—poly(methyl methacrylate)-propylene carbonate-lithium perchlorate electrolyte with HQ as a neutral redox additive were also investigated [104].
Redox-active electrolytes can be successfully applied in electrochemical capacitors and these electrolytes remarkably improve the energy density. It is crucial to use redox additives with a well-reversible and well-defined redox response, as the efficiency of charging/discharging should not be affected by redox process.
A variety of redox couples can be selected depending on the user’s requirements: for the systems based on aqueous or nonaqueous electrolyte, with redox species supposed to be active at the positively or negatively polarized electrode, or which parameters are the most important—high energy, high power, or very long cycle life. Taking into account aqueous-based redox-active electrolytes, the most attractive from the practical point of view are cationic and anionic electroactive species—because of their good solubility in water ensuring high conductivity of the solution. Moreover, the cells operating in organic/polymer-based electrolytes are more expensive due to the proton/ions permeable membranes that have to be used.
There are also a few issues that need to be solved. Redox species cause higher self-discharge of the cell in comparison to ECs with pure EDL formation. Therefore, it would be beneficial to “trap” the redox species within the pores of the material to prevent their movement to the electrolyte bulk. Moreover, the lifetime of EC with redox-active electrolytes should be prolonged, because it is still significantly shorter than the lifetime of the cell operating in the typical capacitive electrolytes.
Nevertheless, redox-active electrolytes in electrochemical capacitors offer an interesting alternative to the solid-state compounds and composites with maintained power and improved charge/discharge efficiency.
European Research Council Starting Grant 2017 project “IMMOCAP” (GA 759603) is acknowledged for financial support covering The Open Access Publishing Fee.
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Consequently, knowledge of exoplanets is considerably more limited than Solar System planets. This chapter reviews the essential characteristics of Solar System planets and associated data derived from a variety of observational approaches. Exoplanet characteristics and their comparison to Solar System planets are provided as well as general detection methods and planned probes to gather additional data.",book:{id:"10210",slug:"solar-system-planets-and-exoplanets",title:"Solar System Planets and Exoplanets",fullTitle:"Solar System Planets and Exoplanets"},signatures:"Joseph Bevelacqua",authors:[{id:"115462",title:"Dr.",name:"Joseph",middleName:"John",surname:"Bevelacqua",slug:"joseph-bevelacqua",fullName:"Joseph Bevelacqua"}]},{id:"65725",title:"On the Deviation of the Lunar Center of Mass to the East: Two Possible Mechanisms Based on Evolution of the Orbit and Rounding Off the Shape of the Moon",slug:"on-the-deviation-of-the-lunar-center-of-mass-to-the-east-two-possible-mechanisms-based-on-evolution-",totalDownloads:1029,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"It is known that the Moon’s center of mass (COM) does not coincide with the geometric center of figure (COF) and the line “COF/COM” is not directed to the center of the Earth, but deviates from it to the South-East. Here, we discuss two mechanisms to explain the deviation of the lunar COM to the East from the mean direction to Earth. The first mechanism considers the secular evolution of the Moon’s orbit, using the effect of the preferred orientation of the satellite with synchronous rotation to the second (empty) orbital focus. It is established that only the scenario with an increase in the orbital eccentricity e leads to the required displacement of the lunar COM to the East. It is important that high-precision calculations confirm an increase e in our era. In order to fully explain the shift of the lunar COM to the East, a second mechanism was developed that takes into account the influence of tidal changes in the shape of the Moon at its gradual removal from the Earth. The second mechanism predicts that the elongation of the lunar figure in the early era was significant. As a result, it was found that the Moon could have been formed in the annular zone at a distance of 3–4 radii of the modern Earth.",book:{id:"8444",slug:"lunar-science",title:"Lunar Science",fullTitle:"Lunar Science"},signatures:"Boris P. Kondratyev",authors:[{id:"277909",title:"Prof.",name:"Boris",middleName:"Petrovich",surname:"Kondratyev",slug:"boris-kondratyev",fullName:"Boris Kondratyev"}]},{id:"68357",title:"Solar System Exploration Augmented by In Situ Resource Utilization: System Analyses, Vehicles, and Moon Bases for Saturn Exploration",slug:"solar-system-exploration-augmented-by-in-situ-resource-utilization-system-analyses-vehicles-and-moon",totalDownloads:859,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"Human and robotic missions to Saturn are presented and analyzed with a range of propulsion options. Historical studies of space exploration, planetary spacecraft and astronomy, in situ resource utilization (ISRU), and industrialization all point to the vastness of natural resources in the solar system. Advanced propulsion is benefitted from these resources in many ways. While advanced propulsion systems were proposed in these historical studies, further investigation of nuclear options using high-power nuclear electric and nuclear pulse propulsion as well as advanced chemical propulsion can significantly enhance these scenarios. Updated analyses based on these historical visions are presented. At Saturn, nuclear pulse propulsion with alternate propellant feed systems and Saturn moon exploration with chemical propulsion and nuclear electric propulsion options are discussed. Issues with using in situ resource utilization on Saturn’s moons are discussed. At Saturn, the best locations for exploration and the use of the moons as central locations for Saturn moon exploration are assessed. Environmental issues on Titan’s surface may present extreme challenges for some ISRU processes. In-space bases for moon-orbiting propellant processing and ground-based processing will be assessed.",book:{id:"7338",slug:"planetology-future-explorations",title:"Planetology",fullTitle:"Planetology - Future Explorations"},signatures:"Bryan Palaszewski",authors:[{id:"279275",title:"M.Sc.",name:"Bryan",middleName:null,surname:"Palaszewski",slug:"bryan-palaszewski",fullName:"Bryan Palaszewski"}]},{id:"65534",title:"Solar System Exploration Augmented by In Situ Resource Utilization: Lunar Base Issues",slug:"solar-system-exploration-augmented-by-in-situ-resource-utilization-lunar-base-issues",totalDownloads:1134,totalCrossrefCites:1,totalDimensionsCites:1,abstract:"Creating a presence and an industrial capability on the Moon is essential for the development of humankind. There are many historical study results that have identified and quantified the lunar resources and analyzed the methods of obtaining and employing those resources. The idea of finding, obtaining, and using these materials is called in situ resource utilization (ISRU). The ISRU research and development efforts have led to new ideas in rocket propulsion. Applications in chemical propulsion, nuclear electric propulsion, and many other propulsion systems will be critical in making the initial lunar base and future lunar industries more sustainable and will lead to brilliant futures for humanity.",book:{id:"8444",slug:"lunar-science",title:"Lunar Science",fullTitle:"Lunar Science"},signatures:"Bryan Palaszewski",authors:[{id:"279275",title:"M.Sc.",name:"Bryan",middleName:null,surname:"Palaszewski",slug:"bryan-palaszewski",fullName:"Bryan Palaszewski"}]},{id:"32533",title:"Measuring the Isotopic Composition of Solar Wind Noble Gases",slug:"measuring-the-isotopic-composition-of-solar-wind-noble-gases",totalDownloads:2789,totalCrossrefCites:6,totalDimensionsCites:9,abstract:null,book:{id:"1617",slug:"exploring-the-solar-wind",title:"Exploring the Solar Wind",fullTitle:"Exploring the Solar Wind"},signatures:"Alex Meshik, Charles Hohenberg, Olga Pravdivtseva and Donald Burnett",authors:[{id:"114740",title:"Prof.",name:"Alexander",middleName:null,surname:"Meshik",slug:"alexander-meshik",fullName:"Alexander Meshik"},{id:"115300",title:"Prof.",name:"Donald",middleName:null,surname:"Burnett",slug:"donald-burnett",fullName:"Donald Burnett"},{id:"115301",title:"Prof.",name:"Charles",middleName:null,surname:"Hohenberg",slug:"charles-hohenberg",fullName:"Charles Hohenberg"},{id:"115302",title:"Dr.",name:"Olga",middleName:null,surname:"Pravdivtseva",slug:"olga-pravdivtseva",fullName:"Olga Pravdivtseva"}]}],onlineFirstChaptersFilter:{topicId:"98",limit:6,offset:0},onlineFirstChaptersCollection:[{id:"82332",title:"Access to Space, Access to the Moon – Two Sides of the Same Coin?",slug:"access-to-space-access-to-the-moon-two-sides-of-the-same-coin-",totalDownloads:13,totalDimensionsCites:0,doi:"10.5772/intechopen.105175",abstract:"The dynamics of human expansion towards space are going through Earth external layers, orbital space and the Moon. With its low gravity, slingshot effect relative to Earth, on-site resources and relative proximity to Earth in the solar system, the renewed space race is effectively returning first to the Moon. A psychological bridge to enlarge our civilization with a permanent bridge to our natural satellite. The development of this Earth-Moon system, requires enormous amount of finances, energy, science, technology, but over all, opportunities. This chapter deals with the efforts and the mental changes that may eventually result from all of these changes.",book:{id:"10955",title:"Lunar Science - Habitat and Humans",coverURL:"https://cdn.intechopen.com/books/images_new/10955.jpg"},signatures:"Yann-Henri Chemin"},{id:"81141",title:"Modeling Radiation Damage in Materials Relevant for Exploration and Settlement on the Moon",slug:"modeling-radiation-damage-in-materials-relevant-for-exploration-and-settlement-on-the-moon",totalDownloads:32,totalDimensionsCites:0,doi:"10.5772/intechopen.102808",abstract:"Understanding the effect of radiation on materials is fundamental for space exploration. Energetic charged particles impacting materials create electronic excitations, atomic displacements, and nuclear fragmentation. Monte Carlo particle transport simulations are the most common approach for modeling radiation damage in materials. However, radiation damage is a multiscale problem, both in time and in length, an aspect treated by the Monte Carlo simulations only to a limited extent. In this chapter, after introducing the Monte Carlo particle transport method, we present a multiscale approach to study different stages of radiation damage which allows for the synergy between the electronic and nuclear effects induced in materials. We focus on cumulative displacement effects induced by radiation below the regime of hadronic interactions. We then discuss selected studies of radiation damage in materials of importance and potential use for the exploration and settlement on the Moon, ranging from semiconductors to alloys and from polymers to the natural regolith. Additionally, we overview some of the novel materials with outstanding properties, such as low weight, increased radiation resistance, and self-healing capabilities with a potential to reduce mission costs and improve prospects for extended human exploration of extraterrestrial bodies.",book:{id:"10955",title:"Lunar Science - Habitat and Humans",coverURL:"https://cdn.intechopen.com/books/images_new/10955.jpg"},signatures:"Natalia E. Koval, Bin Gu, Daniel Muñoz-Santiburcio and Fabiana Da Pieve"},{id:"80241",title:"The Evolution of the Moon’s Orbit Over 100 Million Years and Prospects for the Research in the Moon",slug:"the-evolution-of-the-moon-s-orbit-over-100-million-years-and-prospects-for-the-research-in-the-moon",totalDownloads:65,totalDimensionsCites:0,doi:"10.5772/intechopen.102392",abstract:"As a result of solving the problem of interaction of Solar-system bodies, data on the evolution of the Moon’s orbit were obtained. These data were used as the basis for the development of a mathematical model for the Moon representing its motion over an interval of 100 million years. A program of exploration of the Moon with the aim of creating a permanent base on it is outlined. Such a base is intended for exploring the Earth, the Sun, and outer space.",book:{id:"10955",title:"Lunar Science - Habitat and Humans",coverURL:"https://cdn.intechopen.com/books/images_new/10955.jpg"},signatures:"Joseph J. Smulsky"},{id:"80217",title:"Educational and Scientific Analog Space Missions",slug:"educational-and-scientific-analog-space-missions",totalDownloads:89,totalDimensionsCites:0,doi:"10.5772/intechopen.101392",abstract:"Analog space missions in Poland include international scientific, technological, and business projects designed and realized by a private research company Analog Astronaut Training Center Ltd. (AATC) devoted to the future Moon and Mars exploration. Growing experience in educational aspect of the training as well as continuous development of the habitat and its professional space science laboratory equipment correspond to increased interest of educational organizations, universities, and individual students. We serve unique practical platform for space engineering, space master, and even space doctoral theses. In addition to a wide range of training courses offered for future astronauts, for example, diving, skydiving, rocket workshops, and stratospheric missions, AATC provides a private laboratory to simulate the space environment. It carries out scientific experiments focused on biology and space medicine, as well as addressing several multidisciplinary issues related to the Moon and Mars exploration, including space mining. The main goal of each our analog simulation is to get publishable results, what means that our analog astronauts obtain not only certification of completion of the training but also ability to continue studies and to perform it individually. This chapter summarizes methodology used by us, didactic tools, and obtained results for both educational and scientific analog simulations.",book:{id:"10955",title:"Lunar Science - Habitat and Humans",coverURL:"https://cdn.intechopen.com/books/images_new/10955.jpg"},signatures:"Agata Maria Kołodziejczyk and M. Harasymczuk"},{id:"79544",title:"Regolith and Radiation: The Cosmic Battle",slug:"regolith-and-radiation-the-cosmic-battle",totalDownloads:127,totalDimensionsCites:0,doi:"10.5772/intechopen.101437",abstract:"This chapter discusses regolith utilization in habitat construction mainly from the point of view of radiation protection of humans on missions of long duration. It also considers other key properties such as structural robustness, thermal insulation, and micrometeoroid protection that all have to be considered in parallel when proposing regolith-based solutions. The biological hazards of radiation exposure on the Moon are presented and put in the context of lunar exploration-type missions and current astronaut career dose limits. These factors guide the research in radiation protection done with lunar regolith simulants, which are used in research and development activities on Earth due to the reduced accessibility of returned lunar samples. The ways in which regolith can be used in construction influence its protective properties. Areal density, which plays a key role in the radiation shielding capacity of a given material, can be optimized through different regolith processing techniques. At the same time, density will also affect other important properties of the construction, e.g. thermal insulation. A comprehensive picture of regolith utilization in habitat walls is drawn for the reader to understand the main aspects that are considered in habitat design and construction while maintaining the main focus on radiation protection.",book:{id:"10955",title:"Lunar Science - Habitat and Humans",coverURL:"https://cdn.intechopen.com/books/images_new/10955.jpg"},signatures:"Yulia Akisheva, Yves Gourinat, Nicolas Foray and Aidan Cowley"}],onlineFirstChaptersTotal:5},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:90,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:107,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:33,numberOfPublishedChapters:330,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:14,numberOfPublishedChapters:145,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:9,numberOfPublishedChapters:139,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:123,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:112,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:21,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:10,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:"2753-6580",doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}},{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}}]},series:{item:{id:"6",title:"Infectious Diseases",doi:"10.5772/intechopen.71852",issn:"2631-6188",scope:"This series will provide a comprehensive overview of recent research trends in various Infectious Diseases (as per the most recent Baltimore classification). Topics will include general overviews of infections, immunopathology, diagnosis, treatment, epidemiology, etiology, and current clinical recommendations for managing infectious diseases. Ongoing issues, recent advances, and future diagnostic approaches and therapeutic strategies will also be discussed. This book series will focus on various aspects and properties of infectious diseases whose deep understanding is essential for safeguarding the human race from losing resources and economies due to pathogens.",coverUrl:"https://cdn.intechopen.com/series/covers/6.jpg",latestPublicationDate:"August 12th, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:13,editor:{id:"131400",title:"Prof.",name:"Alfonso J.",middleName:null,surname:"Rodriguez-Morales",slug:"alfonso-j.-rodriguez-morales",fullName:"Alfonso J. Rodriguez-Morales",profilePictureURL:"https://mts.intechopen.com/storage/users/131400/images/system/131400.png",biography:"Dr. Rodriguez-Morales is an expert in tropical and emerging diseases, particularly zoonotic and vector-borne diseases (especially arboviral diseases). He is the president of the Travel Medicine Committee of the Pan-American Infectious Diseases Association (API), as well as the president of the Colombian Association of Infectious Diseases (ACIN). He is a member of the Committee on Tropical Medicine, Zoonoses, and Travel Medicine of ACIN. He is a vice-president of the Latin American Society for Travel Medicine (SLAMVI) and a Member of the Council of the International Society for Infectious Diseases (ISID). Since 2014, he has been recognized as a Senior Researcher, at the Ministry of Science of Colombia. He is a professor at the Faculty of Medicine of the Fundacion Universitaria Autonoma de las Americas, in Pereira, Risaralda, Colombia. He is an External Professor, Master in Research on Tropical Medicine and International Health, Universitat de Barcelona, Spain. He is also a professor at the Master in Clinical Epidemiology and Biostatistics, Universidad Científica del Sur, Lima, Peru. In 2021 he has been awarded the “Raul Isturiz Award” Medal of the API. Also, in 2021, he was awarded with the “Jose Felix Patiño” Asclepius Staff Medal of the Colombian Medical College, due to his scientific contributions to COVID-19 during the pandemic. He is currently the Editor in Chief of the journal Travel Medicine and Infectious Diseases. His Scopus H index is 47 (Google Scholar H index, 68).",institutionString:"Institución Universitaria Visión de las Américas, Colombia",institution:null},editorTwo:null,editorThree:null},subseries:{paginationCount:4,paginationItems:[{id:"14",title:"Cell and Molecular Biology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/14.jpg",isOpenForSubmission:!0,editor:{id:"165627",title:"Dr.",name:"Rosa María",middleName:null,surname:"Martínez-Espinosa",slug:"rosa-maria-martinez-espinosa",fullName:"Rosa María Martínez-Espinosa",profilePictureURL:"https://mts.intechopen.com/storage/users/165627/images/system/165627.jpeg",biography:"Dr. Rosa María Martínez-Espinosa has been a Spanish Full Professor since 2020 (Biochemistry and Molecular Biology) and is currently Vice-President of International Relations and Cooperation development and leader of the research group 'Applied Biochemistry” (University of Alicante, Spain). Other positions she has held at the university include Vice-Dean of Master Programs, Vice-Dean of the Degree in Biology and Vice-Dean for Mobility and Enterprise and Engagement at the Faculty of Science (University of Alicante). She received her Bachelor in Biology in 1998 (University of Alicante) and her PhD in 2003 (Biochemistry, University of Alicante). She undertook post-doctoral research at the University of East Anglia (Norwich, U.K. 2004-2005; 2007-2008).\nHer multidisciplinary research focuses on investigating archaea and their potential applications in biotechnology. She has an H-index of 21. She has authored one patent and has published more than 70 indexed papers and around 60 book chapters.\nShe has contributed to more than 150 national and international meetings during the last 15 years. Her research interests include archaea metabolism, enzymes purification and characterization, gene regulation, carotenoids and bioplastics production, antioxidant\ncompounds, waste water treatments, and brines bioremediation.\nRosa María’s other roles include editorial board member for several journals related\nto biochemistry, reviewer for more than 60 journals (biochemistry, molecular biology, biotechnology, chemistry and microbiology) and president of several organizing committees in international meetings related to the N-cycle or respiratory processes.",institutionString:null,institution:{name:"University of Alicante",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null},{id:"15",title:"Chemical Biology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/15.jpg",isOpenForSubmission:!0,editor:{id:"441442",title:"Dr.",name:"Şükrü",middleName:null,surname:"Beydemir",slug:"sukru-beydemir",fullName:"Şükrü Beydemir",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003GsUoIQAV/Profile_Picture_1634557147521",biography:"Dr. Şükrü Beydemir obtained a BSc in Chemistry in 1995 from Yüzüncü Yıl University, MSc in Biochemistry in 1998, and PhD in Biochemistry in 2002 from Atatürk University, Turkey. He performed post-doctoral studies at Max-Planck Institute, Germany, and University of Florence, Italy in addition to making several scientific visits abroad. He currently works as a Full Professor of Biochemistry in the Faculty of Pharmacy, Anadolu University, Turkey. Dr. Beydemir has published over a hundred scientific papers spanning protein biochemistry, enzymology and medicinal chemistry, reviews, book chapters and presented several conferences to scientists worldwide. He has received numerous publication awards from various international scientific councils. He serves in the Editorial Board of several international journals. Dr. Beydemir is also Rector of Bilecik Şeyh Edebali University, Turkey.",institutionString:null,institution:{name:"Anadolu University",institutionURL:null,country:{name:"Turkey"}}},editorTwo:{id:"13652",title:"Prof.",name:"Deniz",middleName:null,surname:"Ekinci",slug:"deniz-ekinci",fullName:"Deniz Ekinci",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYLT1QAO/Profile_Picture_1634557223079",biography:"Dr. Deniz Ekinci obtained a BSc in Chemistry in 2004, MSc in Biochemistry in 2006, and PhD in Biochemistry in 2009 from Atatürk University, Turkey. He studied at Stetson University, USA, in 2007-2008 and at the Max Planck Institute of Molecular Cell Biology and Genetics, Germany, in 2009-2010. Dr. Ekinci currently works as a Full Professor of Biochemistry in the Faculty of Agriculture and is the Head of the Enzyme and Microbial Biotechnology Division, Ondokuz Mayıs University, Turkey. He is a member of the Turkish Biochemical Society, American Chemical Society, and German Genetics society. Dr. Ekinci published around ninety scientific papers, reviews and book chapters, and presented several conferences to scientists. He has received numerous publication awards from several scientific councils. Dr. Ekinci serves as the Editor in Chief of four international books and is involved in the Editorial Board of several international journals.",institutionString:null,institution:{name:"Ondokuz Mayıs University",institutionURL:null,country:{name:"Turkey"}}},editorThree:null},{id:"17",title:"Metabolism",coverUrl:"https://cdn.intechopen.com/series_topics/covers/17.jpg",isOpenForSubmission:!0,editor:{id:"138626",title:"Dr.",name:"Yannis",middleName:null,surname:"Karamanos",slug:"yannis-karamanos",fullName:"Yannis Karamanos",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002g6Jv2QAE/Profile_Picture_1629356660984",biography:"Yannis Karamanos, born in Greece in 1953, completed his pre-graduate studies at the Université Pierre et Marie Curie, Paris, then his Masters and Doctoral degree at the Université de Lille (1983). He was associate professor at the University of Limoges (1987) before becoming full professor of biochemistry at the Université d’Artois (1996). He worked on the structure-function relationships of glycoconjugates and his main project was the investigations on the biological roles of the de-N-glycosylation enzymes (Endo-N-acetyl-β-D-glucosaminidase and peptide-N4-(N-acetyl-β-glucosaminyl) asparagine amidase). From 2002 he contributes to the understanding of the Blood-brain barrier functioning using proteomics approaches. He has published more than 70 papers. His teaching areas are energy metabolism and regulation, integration and organ specialization and metabolic adaptation.",institutionString:null,institution:{name:"Artois University",institutionURL:null,country:{name:"France"}}},editorTwo:null,editorThree:null},{id:"18",title:"Proteomics",coverUrl:"https://cdn.intechopen.com/series_topics/covers/18.jpg",isOpenForSubmission:!0,editor:{id:"200689",title:"Prof.",name:"Paolo",middleName:null,surname:"Iadarola",slug:"paolo-iadarola",fullName:"Paolo Iadarola",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSCl8QAG/Profile_Picture_1623568118342",biography:"Paolo Iadarola graduated with a degree in Chemistry from the University of Pavia (Italy) in July 1972. He then worked as an Assistant Professor at the Faculty of Science of the same University until 1984. In 1985, Prof. Iadarola became Associate Professor at the Department of Biology and Biotechnologies of the University of Pavia and retired in October 2017. Since then, he has been working as an Adjunct Professor in the same Department at the University of Pavia. His research activity during the first years was primarily focused on the purification and structural characterization of enzymes from animal and plant sources. During this period, Prof. Iadarola familiarized himself with the conventional techniques used in column chromatography, spectrophotometry, manual Edman degradation, and electrophoresis). Since 1995, he has been working on: i) the determination in biological fluids (serum, urine, bronchoalveolar lavage, sputum) of proteolytic activities involved in the degradation processes of connective tissue matrix, and ii) on the identification of biological markers of lung diseases. In this context, he has developed and validated new methodologies (e.g., Capillary Electrophoresis coupled to Laser-Induced Fluorescence, CE-LIF) whose application enabled him to determine both the amounts of biochemical markers (Desmosines) in urine/serum of patients affected by Chronic Obstructive Pulmonary Disease (COPD) and the activity of proteolytic enzymes (Human Neutrophil Elastase, Cathepsin G, Pseudomonas aeruginosa elastase) in sputa of these patients. More recently, Prof. Iadarola was involved in developing techniques such as two-dimensional electrophoresis coupled to liquid chromatography/mass spectrometry (2DE-LC/MS) for the proteomic analysis of biological fluids aimed at the identification of potential biomarkers of different lung diseases. He is the author of about 150 publications (According to Scopus: H-Index: 23; Total citations: 1568- According to WOS: H-Index: 20; Total Citations: 1296) of peer-reviewed international journals. He is a Consultant Reviewer for several journals, including the Journal of Chromatography A, Journal of Chromatography B, Plos ONE, Proteomes, International Journal of Molecular Science, Biotech, Electrophoresis, and others. He is also Associate Editor of Biotech.",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorTwo:{id:"201414",title:"Dr.",name:"Simona",middleName:null,surname:"Viglio",slug:"simona-viglio",fullName:"Simona Viglio",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRKDHQA4/Profile_Picture_1630402531487",biography:"Simona Viglio is an Associate Professor of Biochemistry at the Department of Molecular Medicine at the University of Pavia. She has been working since 1995 on the determination of proteolytic enzymes involved in the degradation process of connective tissue matrix and on the identification of biological markers of lung diseases. She gained considerable experience in developing and validating new methodologies whose applications allowed her to determine both the amount of biomarkers (Desmosine and Isodesmosine) in the urine of patients affected by COPD, and the activity of proteolytic enzymes (HNE, Cathepsin G, Pseudomonas aeruginosa elastase) in the sputa of these patients. Simona Viglio was also involved in research dealing with the supplementation of amino acids in patients with brain injury and chronic heart failure. She is presently engaged in the development of 2-DE and LC-MS techniques for the study of proteomics in biological fluids. The aim of this research is the identification of potential biomarkers of lung diseases. She is an author of about 90 publications (According to Scopus: H-Index: 23; According to WOS: H-Index: 20) on peer-reviewed journals, a member of the “Società Italiana di Biochimica e Biologia Molecolare,“ and a Consultant Reviewer for International Journal of Molecular Science, Journal of Chromatography A, COPD, Plos ONE and Nutritional Neuroscience.",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorThree:null}]},overviewPageOFChapters:{paginationCount:42,paginationItems:[{id:"82914",title:"Glance on the Critical Role of IL-23 Receptor Gene Variations in Inflammation-Induced Carcinogenesis",doi:"10.5772/intechopen.105049",signatures:"Mohammed El-Gedamy",slug:"glance-on-the-critical-role-of-il-23-receptor-gene-variations-in-inflammation-induced-carcinogenesis",totalDownloads:9,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Chemokines Updates",coverURL:"https://cdn.intechopen.com/books/images_new/11672.jpg",subseries:{id:"18",title:"Proteomics"}}},{id:"82875",title:"Lipidomics as a Tool in the Diagnosis and Clinical Therapy",doi:"10.5772/intechopen.105857",signatures:"María Elizbeth Alvarez Sánchez, Erick Nolasco Ontiveros, Rodrigo Arreola, Adriana Montserrat Espinosa González, Ana María García Bores, Roberto Eduardo López Urrutia, Ignacio Peñalosa Castro, María del Socorro Sánchez Correa and Edgar Antonio Estrella Parra",slug:"lipidomics-as-a-tool-in-the-diagnosis-and-clinical-therapy",totalDownloads:7,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Fatty Acids - Recent Advances",coverURL:"https://cdn.intechopen.com/books/images_new/11669.jpg",subseries:{id:"17",title:"Metabolism"}}},{id:"82440",title:"Lipid Metabolism and Associated Molecular Signaling Events in Autoimmune Disease",doi:"10.5772/intechopen.105746",signatures:"Mohan Vanditha, Sonu Das and Mathew John",slug:"lipid-metabolism-and-associated-molecular-signaling-events-in-autoimmune-disease",totalDownloads:17,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Fatty Acids - Recent Advances",coverURL:"https://cdn.intechopen.com/books/images_new/11669.jpg",subseries:{id:"17",title:"Metabolism"}}},{id:"82483",title:"Oxidative Stress in Cardiovascular Diseases",doi:"10.5772/intechopen.105891",signatures:"Laura Mourino-Alvarez, Tamara Sastre-Oliva, Nerea Corbacho-Alonso and Maria G. Barderas",slug:"oxidative-stress-in-cardiovascular-diseases",totalDownloads:10,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Importance of Oxidative Stress and Antioxidant System in Health and Disease",coverURL:"https://cdn.intechopen.com/books/images_new/11671.jpg",subseries:{id:"15",title:"Chemical Biology"}}}]},overviewPagePublishedBooks:{paginationCount:33,paginationItems:[{type:"book",id:"7006",title:"Biochemistry and Health Benefits of Fatty Acids",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7006.jpg",slug:"biochemistry-and-health-benefits-of-fatty-acids",publishedDate:"December 19th 2018",editedByType:"Edited by",bookSignature:"Viduranga Waisundara",hash:"c93a00abd68b5eba67e5e719f67fd20b",volumeInSeries:1,fullTitle:"Biochemistry and Health Benefits of Fatty Acids",editors:[{id:"194281",title:"Dr.",name:"Viduranga Y.",middleName:null,surname:"Waisundara",slug:"viduranga-y.-waisundara",fullName:"Viduranga Y. Waisundara",profilePictureURL:"https://mts.intechopen.com/storage/users/194281/images/system/194281.jpg",biography:"Dr. Viduranga Waisundara obtained her Ph.D. in Food Science\nand Technology from the Department of Chemistry, National\nUniversity of Singapore, in 2010. She was a lecturer at Temasek Polytechnic, Singapore from July 2009 to March 2013.\nShe relocated to her motherland of Sri Lanka and spearheaded the Functional Food Product Development Project at the\nNational Institute of Fundamental Studies from April 2013 to\nOctober 2016. She was a senior lecturer on a temporary basis at the Department of\nFood Technology, Faculty of Technology, Rajarata University of Sri Lanka. She is\ncurrently Deputy Principal of the Australian College of Business and Technology –\nKandy Campus, Sri Lanka. She is also the Global Harmonization Initiative (GHI)",institutionString:"Australian College of Business & Technology",institution:{name:"Kobe College",institutionURL:null,country:{name:"Japan"}}}]},{type:"book",id:"6820",title:"Keratin",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/6820.jpg",slug:"keratin",publishedDate:"December 19th 2018",editedByType:"Edited by",bookSignature:"Miroslav Blumenberg",hash:"6def75cd4b6b5324a02b6dc0359896d0",volumeInSeries:2,fullTitle:"Keratin",editors:[{id:"31610",title:"Dr.",name:"Miroslav",middleName:null,surname:"Blumenberg",slug:"miroslav-blumenberg",fullName:"Miroslav Blumenberg",profilePictureURL:"https://mts.intechopen.com/storage/users/31610/images/system/31610.jpg",biography:"Miroslav Blumenberg, Ph.D., was born in Subotica and received his BSc in Belgrade, Yugoslavia. He completed his Ph.D. at MIT in Organic Chemistry; he followed up his Ph.D. with two postdoctoral study periods at Stanford University. Since 1983, he has been a faculty member of the RO Perelman Department of Dermatology, NYU School of Medicine, where he is codirector of a training grant in cutaneous biology. Dr. Blumenberg’s research is focused on the epidermis, expression of keratin genes, transcription profiling, keratinocyte differentiation, inflammatory diseases and cancers, and most recently the effects of the microbiome on the skin. He has published more than 100 peer-reviewed research articles and graduated numerous Ph.D. and postdoctoral students.",institutionString:null,institution:{name:"New York University Langone Medical Center",institutionURL:null,country:{name:"United States of America"}}}]},{type:"book",id:"7978",title:"Vitamin A",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7978.jpg",slug:"vitamin-a",publishedDate:"May 15th 2019",editedByType:"Edited by",bookSignature:"Leila Queiroz Zepka, Veridiana Vera de Rosso and Eduardo Jacob-Lopes",hash:"dad04a658ab9e3d851d23705980a688b",volumeInSeries:3,fullTitle:"Vitamin A",editors:[{id:"261969",title:"Dr.",name:"Leila",middleName:null,surname:"Queiroz Zepka",slug:"leila-queiroz-zepka",fullName:"Leila Queiroz Zepka",profilePictureURL:"https://mts.intechopen.com/storage/users/261969/images/system/261969.png",biography:"Prof. Dr. Leila Queiroz Zepka is currently an associate professor in the Department of Food Technology and Science, Federal University of Santa Maria, Brazil. She has more than fifteen years of teaching and research experience. She has published more than 550 scientific publications/communications, including 15 books, 50 book chapters, 100 original research papers, 380 research communications in national and international conferences, and 12 patents. She is a member of the editorial board of five journals and acts as a reviewer for several national and international journals. 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The preliminary objectives of the study are to understand and develop the evidence-based tools and interventions for the control and prevention of malaria in different sites of the INDIA. Alongside, with the help of next-generation genomics study, the team has studied the antimalarial drug resistance in India. Further, he has extended his research in the development of Humanized mice for the study of liver-stage malaria and identification of molecular marker(s) for the Artemisinin resistance. At present, his research focuses on understanding the role of B cells in the activation of CD8+ T cells in malaria. Received the CSIR-SRF (Senior Research Fellow) award-2018, FIMSA (Federation of Immunological Societies of Asia-Oceania) Travel Bursary award to attend the IUIS-IIS-FIMSA Immunology course-2019',institutionString:"Nirma University",institution:{name:"Nirma University",country:{name:"India"}}},{id:"334383",title:"Ph.D.",name:"Simone",middleName:"Ulrich",surname:"Ulrich Picoli",slug:"simone-ulrich-picoli",fullName:"Simone Ulrich Picoli",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/334383/images/15919_n.jpg",biography:"Graduated in Pharmacy from Universidade Luterana do Brasil (1999), Master in Agricultural and Environmental Microbiology from Federal University of Rio Grande do Sul (2002), Specialization in Clinical Microbiology from Universidade de São Paulo, USP (2007) and PhD in Sciences in Gastroenterology and Hepatology (2012). She is currently an Adjunct Professor at Feevale University in Medicine and Biomedicine courses and a permanent professor of the Academic Master\\'s Degree in Virology. She has experience in the field of Microbiology, with an emphasis on Bacteriology, working mainly on the following topics: bacteriophages, bacterial resistance, clinical microbiology and food microbiology.",institutionString:null,institution:{name:"Universidade Feevale",country:{name:"Brazil"}}},{id:"229220",title:"Dr.",name:"Amjad",middleName:"Islam",surname:"Aqib",slug:"amjad-aqib",fullName:"Amjad Aqib",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/229220/images/system/229220.png",biography:"Dr. Amjad Islam Aqib obtained a DVM and MSc (Hons) from University of Agriculture Faisalabad (UAF), Pakistan, and a PhD from the University of Veterinary and Animal Sciences Lahore, Pakistan. Dr. Aqib joined the Department of Clinical Medicine and Surgery at UAF for one year as an assistant professor where he developed a research laboratory designated for pathogenic bacteria. Since 2018, he has been Assistant Professor/Officer in-charge, Department of Medicine, Manager Research Operations and Development-ORIC, and President One Health Club at Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Pakistan. He has nearly 100 publications to his credit. His research interests include epidemiological patterns and molecular analysis of antimicrobial resistance and modulation and vaccine development against animal pathogens of public health concern.",institutionString:"Cholistan University of Veterinary and Animal Sciences",institution:{name:"University of Agriculture Faisalabad",country:{name:"Pakistan"}}},{id:"333753",title:"Dr.",name:"Rais",middleName:null,surname:"Ahmed",slug:"rais-ahmed",fullName:"Rais Ahmed",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/333753/images/20168_n.jpg",biography:null,institutionString:null,institution:{name:"University of Agriculture Faisalabad",country:{name:"Pakistan"}}},{id:"62900",title:"Prof.",name:"Fethi",middleName:null,surname:"Derbel",slug:"fethi-derbel",fullName:"Fethi Derbel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/62900/images/system/62900.jpeg",biography:"Professor Fethi Derbel was born in 1960 in Tunisia. He received his medical degree from the Sousse Faculty of Medicine at Sousse, University of Sousse, Tunisia. He completed his surgical residency in General Surgery at the University Hospital Farhat Hached of Sousse and was a member of the Unit of Liver Transplantation in the University of Rennes, France. He then worked in the Department of Surgery at the Sahloul University Hospital in Sousse. Professor Derbel is presently working at the Clinique les Oliviers, Sousse, Tunisia. His hospital activities are mostly concerned with laparoscopic, colorectal, pancreatic, hepatobiliary, and gastric surgery. He is also very interested in hernia surgery and performs ventral hernia repairs and inguinal hernia repairs. He has been a member of the GREPA and Tunisian Hernia Society (THS). During his residency, he managed patients suffering from diabetic foot, and he was very interested in this pathology. For this reason, he decided to coordinate a book project dealing with the diabetic foot. Professor Derbel has published many articles in journals and collaborates intensively with IntechOpen Access Publisher as an editor.",institutionString:"Clinique les Oliviers",institution:null},{id:"300144",title:"Dr.",name:"Meriem",middleName:null,surname:"Braiki",slug:"meriem-braiki",fullName:"Meriem Braiki",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/300144/images/system/300144.jpg",biography:"Dr. Meriem Braiki is a specialist in pediatric surgeon from Tunisia. She was born in 1985. She received her medical degree from the University of Medicine at Sousse, Tunisia. She achieved her surgical residency training periods in Pediatric Surgery departments at University Hospitals in Monastir, Tunis and France.\r\nShe is currently working at the Pediatric surgery department, Sidi Bouzid Hospital, Tunisia. Her hospital activities are mostly concerned with laparoscopic, parietal, urological and digestive surgery. She has published several articles in diffrent journals.",institutionString:"Sidi Bouzid Regional Hospital",institution:null},{id:"229481",title:"Dr.",name:"Erika M.",middleName:"Martins",surname:"de Carvalho",slug:"erika-m.-de-carvalho",fullName:"Erika M. de Carvalho",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/229481/images/6397_n.jpg",biography:null,institutionString:null,institution:{name:"Oswaldo Cruz Foundation",country:{name:"Brazil"}}},{id:"186537",title:"Prof.",name:"Tonay",middleName:null,surname:"Inceboz",slug:"tonay-inceboz",fullName:"Tonay Inceboz",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/186537/images/system/186537.jfif",biography:"I was graduated from Ege University of Medical Faculty (Turkey) in 1988 and completed his Med. PhD degree in Medical Parasitology at the same university. I became an Associate Professor in 2008 and Professor in 2014. I am currently working as a Professor at the Department of Medical Parasitology at Dokuz Eylul University, Izmir, Turkey.\n\nI have given many lectures, presentations in different academic meetings. I have more than 60 articles in peer-reviewed journals, 18 book chapters, 1 book editorship.\n\nMy research interests are Echinococcus granulosus, Echinococcus multilocularis (diagnosis, life cycle, in vitro and in vivo cultivation), and Trichomonas vaginalis (diagnosis, PCR, and in vitro cultivation).",institutionString:"Dokuz Eylül University",institution:{name:"Dokuz Eylül University",country:{name:"Turkey"}}},{id:"71812",title:"Prof.",name:"Hanem Fathy",middleName:"Fathy",surname:"Khater",slug:"hanem-fathy-khater",fullName:"Hanem Fathy Khater",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/71812/images/1167_n.jpg",biography:"Prof. Khater is a Professor of Parasitology at Benha University, Egypt. She studied for her doctoral degree, at the Department of Entomology, College of Agriculture, Food and Natural Resources, University of Missouri, Columbia, USA. She has completed her Ph.D. degrees in Parasitology in Egypt, from where she got the award for “the best scientific Ph.D. dissertation”. She worked at the School of Biological Sciences, Bristol, England, the UK in controlling insects of medical and veterinary importance as a grant from Newton Mosharafa, the British Council. Her research is focused on searching of pesticides against mosquitoes, house flies, lice, green bottle fly, camel nasal botfly, soft and hard ticks, mites, and the diamondback moth as well as control of several parasites using safe and natural materials to avoid drug resistances and environmental contamination.",institutionString:null,institution:{name:"Banha University",country:{name:"Egypt"}}},{id:"99780",title:"Prof.",name:"Omolade",middleName:"Olayinka",surname:"Okwa",slug:"omolade-okwa",fullName:"Omolade Okwa",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/99780/images/system/99780.jpg",biography:"Omolade Olayinka Okwa is presently a Professor of Parasitology at Lagos State University, Nigeria. She has a PhD in Parasitology (1997), an MSc in Cellular Parasitology (1992), and a BSc (Hons) Zoology (1990) all from the University of Ibadan, Nigeria. She teaches parasitology at the undergraduate and postgraduate levels. She was a recipient of a Commonwealth fellowship supported by British Council tenable at the Centre for Entomology and Parasitology (CAEP), Keele University, United Kingdom between 2004 and 2005. She was awarded an Honorary Visiting Research Fellow at the same university from 2005 to 2007. \nShe has been an external examiner to the Department of Veterinary Microbiology and Parasitology, University of Ibadan, MSc programme between 2010 and 2012. She is a member of the Nigerian Society of Experimental Biology (NISEB), Parasitology and Public Health Society of Nigeria (PPSN), Science Association of Nigeria (SAN), Zoological Society of Nigeria (ZSN), and is Vice Chairperson of the Organisation of Women in Science (OWSG), LASU chapter. She served as Head of Department of Zoology and Environmental Biology, Lagos State University from 2007 to 2010 and 2014 to 2016. She is a reviewer for several local and international journals such as Unilag Journal of Science, Libyan Journal of Medicine, Journal of Medicine and Medical Sciences, and Annual Research and Review in Science. \nShe has authored 45 scientific research publications in local and international journals, 8 scientific reviews, 4 books, and 3 book chapters, which includes the books “Malaria Parasites” and “Malaria” which are IntechOpen access publications.",institutionString:"Lagos State University",institution:{name:"Lagos State University",country:{name:"Nigeria"}}},{id:"273100",title:"Dr.",name:"Vijay",middleName:null,surname:"Gayam",slug:"vijay-gayam",fullName:"Vijay Gayam",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/273100/images/system/273100.jpeg",biography:"Dr. Vijay Bhaskar Reddy Gayam is currently practicing as an internist at Interfaith Medical Center in Brooklyn, New York, USA. He is also a Clinical Assistant Professor at the SUNY Downstate University Hospital and Adjunct Professor of Medicine at the American University of Antigua. He is a holder of an M.B.B.S. degree bestowed to him by Osmania Medical College and received his M.D. at Interfaith Medical Center. His career goals thus far have heavily focused on direct patient care, medical education, and clinical research. He currently serves in two leadership capacities; Assistant Program Director of Medicine at Interfaith Medical Center and as a Councilor for the American\r\nFederation for Medical Research. As a true academician and researcher, he has more than 50 papers indexed in international peer-reviewed journals. He has also presented numerous papers in multiple national and international scientific conferences. His areas of research interest include general internal medicine, gastroenterology and hepatology. He serves as an editor, editorial board member and reviewer for multiple international journals. His research on Hepatitis C has been very successful and has led to multiple research awards, including the 'Equity in Prevention and Treatment Award” from the New York Department of Health Viral Hepatitis Symposium (2018) and the 'Presidential Poster Award” awarded to him by the American College of Gastroenterology (2018). He was also awarded 'Outstanding Clinician in General Medicine” by Venus International Foundation for his extensive research expertise and services, perform over and above the standard expected in the advancement of healthcare, patient safety and quality of care.",institutionString:"Interfaith Medical Center",institution:{name:"Interfaith Medical Center",country:{name:"United States of America"}}},{id:"93517",title:"Dr.",name:"Clement",middleName:"Adebajo",surname:"Meseko",slug:"clement-meseko",fullName:"Clement Meseko",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/93517/images/system/93517.jpg",biography:"Dr. Clement Meseko obtained DVM and PhD degree in Veterinary Medicine and Virology respectively. He has worked for over 20 years in both private and public sectors including the academia, contributing to knowledge and control of infectious disease. Through the application of epidemiological skill, classical and molecular virological skills, he investigates viruses of economic and public health importance for the mitigation of the negative impact on people, animal and the environment in the context of Onehealth. \r\nDr. Meseko’s field experience on animal and zoonotic diseases and pathogen dynamics at the human-animal interface over the years shaped his carrier in research and scientific inquiries. He has been part of the investigation of Highly Pathogenic Avian Influenza incursions in sub Saharan Africa and monitors swine Influenza (Pandemic influenza Virus) agro-ecology and potential for interspecies transmission. He has authored and reviewed a number of journal articles and book chapters.",institutionString:"National Veterinary Research Institute",institution:{name:"National Veterinary Research Institute",country:{name:"Nigeria"}}},{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",biography:"Professor Dr. Shailendra K. Saxena is a vice dean and professor at King George's Medical University, Lucknow, India. His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research work has been published in various high-impact factor journals (Science, PNAS, Nature Medicine) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. Dr. Saxena is a fellow of various international societies/academies including the Royal College of Pathologists, United Kingdom; Royal Society of Medicine, London; Royal Society of Biology, United Kingdom; Royal Society of Chemistry, London; and Academy of Translational Medicine Professionals, Austria. He was named a Global Leader in Science by The Scientist. He is also an international opinion leader/expert in vaccination for Japanese encephalitis by IPIC (UK).",institutionString:"King George's Medical University",institution:{name:"King George's Medical University",country:{name:"India"}}},{id:"94928",title:"Dr.",name:"Takuo",middleName:null,surname:"Mizukami",slug:"takuo-mizukami",fullName:"Takuo Mizukami",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/94928/images/6402_n.jpg",biography:null,institutionString:null,institution:{name:"National Institute of Infectious Diseases",country:{name:"Japan"}}},{id:"233433",title:"Dr.",name:"Yulia",middleName:null,surname:"Desheva",slug:"yulia-desheva",fullName:"Yulia Desheva",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/233433/images/system/233433.png",biography:"Dr. Yulia Desheva is a leading researcher at the Institute of Experimental Medicine, St. Petersburg, Russia. She is a professor in the Stomatology Faculty, St. Petersburg State University. She has expertise in the development and evaluation of a wide range of live mucosal vaccines against influenza and bacterial complications. Her research interests include immunity against influenza and COVID-19 and the development of immunization schemes for high-risk individuals.",institutionString:'Federal State Budgetary Scientific Institution "Institute of Experimental Medicine"',institution:null},{id:"238958",title:"Mr.",name:"Atamjit",middleName:null,surname:"Singh",slug:"atamjit-singh",fullName:"Atamjit Singh",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/238958/images/6575_n.jpg",biography:null,institutionString:null,institution:null},{id:"252058",title:"M.Sc.",name:"Juan",middleName:null,surname:"Sulca",slug:"juan-sulca",fullName:"Juan Sulca",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/252058/images/12834_n.jpg",biography:null,institutionString:null,institution:null},{id:"191392",title:"Dr.",name:"Marimuthu",middleName:null,surname:"Govindarajan",slug:"marimuthu-govindarajan",fullName:"Marimuthu Govindarajan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/191392/images/5828_n.jpg",biography:"Dr. M. Govindarajan completed his BSc degree in Zoology at Government Arts College (Autonomous), Kumbakonam, and MSc, MPhil, and PhD degrees at Annamalai University, Annamalai Nagar, Tamil Nadu, India. He is serving as an assistant professor at the Department of Zoology, Annamalai University. His research interests include isolation, identification, and characterization of biologically active molecules from plants and microbes. He has identified more than 20 pure compounds with high mosquitocidal activity and also conducted high-quality research on photochemistry and nanosynthesis. He has published more than 150 studies in journals with impact factor and 2 books in Lambert Academic Publishing, Germany. He serves as an editorial board member in various national and international scientific journals.",institutionString:null,institution:null},{id:"274660",title:"Dr.",name:"Damodar",middleName:null,surname:"Paudel",slug:"damodar-paudel",fullName:"Damodar Paudel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/274660/images/8176_n.jpg",biography:"I am DrDamodar Paudel,currently working as consultant Physician in Nepal police Hospital.",institutionString:null,institution:null},{id:"241562",title:"Dr.",name:"Melvin",middleName:null,surname:"Sanicas",slug:"melvin-sanicas",fullName:"Melvin Sanicas",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/241562/images/6699_n.jpg",biography:null,institutionString:null,institution:null},{id:"322007",title:"Dr.",name:"Maria Elizbeth",middleName:null,surname:"Alvarez-Sánchez",slug:"maria-elizbeth-alvarez-sanchez",fullName:"Maria Elizbeth Alvarez-Sánchez",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Universidad Autónoma de la Ciudad de México",country:{name:"Mexico"}}},{id:"337443",title:"Dr.",name:"Juan",middleName:null,surname:"A. 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