Examples of economic balance for three cases of the same profile.
\\n\\n
Released this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\\n\\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
\\n"}]',published:!0,mainMedia:{caption:"Highly Cited",originalUrl:"/media/original/117"}},components:[{type:"htmlEditorComponent",content:'IntechOpen is proud to announce that 191 of our authors have made the Clarivate™ Highly Cited Researchers List for 2020, ranking them among the top 1% most-cited.
\n\nThroughout the years, the list has named a total of 261 IntechOpen authors as Highly Cited. Of those researchers, 69 have been featured on the list multiple times.
\n\n\n\nReleased this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\n\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
\n'}],latestNews:[{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"},{slug:"introducing-intechopen-book-series-a-new-publishing-format-for-oa-books-20210915",title:"Introducing IntechOpen Book Series - A New Publishing Format for OA Books"}]},book:{item:{type:"book",id:"640",leadTitle:null,fullTitle:"Modern Arthroscopy",title:"Modern Arthroscopy",subtitle:null,reviewType:"peer-reviewed",abstract:"Modern Arthroscopy will assist practitioners to stay current in the rapidly changing field of arthroscopic surgery. 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2010",bookSignature:"Krzysztof Smigorski",coverURL:"https://cdn.intechopen.com/books/images_new/5115.jpg",licenceType:"CC BY-NC-SA 3.0",editedByType:"Edited by",editors:[{id:"12528",title:"Dr.",name:"Krzysztof",middleName:null,surname:"Smigorski",slug:"krzysztof-smigorski",fullName:"Krzysztof Smigorski"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}}},ofsBook:{item:{type:"book",id:"11433",leadTitle:null,title:"Human Migration in the Last Three Centuries",subtitle:null,reviewType:"peer-reviewed",abstract:"\r\n\tIn March 2022, another book on human migration seems important when the events or tragedies unfolding in Eastern Europe are considered. People have always migrated and have moved, but, specifically looking at the last three hundred years, involuntary migration is on the rise. Involuntary migration does not only affect Europe; Asia, Africa, and North as well as South America, have had their fair share of natural catastrophes, invasions, and wars.
\r\n\tThis book will intend to look at different migrant patterns, voluntary and involuntary migration, over the last three centuries. What influenced people to leave their home countries, family, and friends and settle somewhere else? The book may include histories of the 19th century, consider tragedies and movements activated by political events in the 20th century, and/or look at recent events of the 21st century. Push and pull factors are important points. While most of us may be influenced in a negative way by the current happenings in Eastern Europe, the Russian invasion and resulting tragedies also demonstrate some very positive human traits – the preparedness of Ukraine’s surrounding countries to help those in need and to provide a safe place for the present.
\r\n\tWhether one looks at voluntary or involuntary migration into any country, after a period of adjustment, migrants do play a positive role. The research found that migrants contribute to the economy (food, shelter, employment, tax) and enrich a country’s cultural norms. Prerequisites for successful settlements are that the host society adopts a tolerant approach and that the migrants recognize the law and the language of the host country. Nothing is ever easy or without controversy, but I am a migrant (German Australian), and life in Australia has been relatively harmonious. Issues that could be considered in the book are multicultural societies (do monocultural societies still exist?) and theories of acculturation versus integration (settlement processes).
\r\n\tTwo further issues are very important in relation to human migration. There is climate change, global warming, and the environment, which clearly affect people’s movement. Small island populations are very concerned about rising sea levels. 2021 has also seen floods costing human lives: Turkey (August 2021), Brazil (December 2021), Chile (January 2021), and South India (November 2021), to name but a few. In Australia (March 2022), farms and whole townships in New South Wales and Queensland have been flooded for the second time in five years, and plans to resettle these towns are considered. Official and social media provide ample coverage of the events, which leads me to the next issue. There is today’s very important role of the media, of the official and social media. We are constantly bombarded with images of human war tragedies and flood victims. People in industrialized, western countries must be the best-informed populace. How far do the images and up-to-date TV news influence us, make us change our behavior, and perhaps even consider us more generous than we have been?
\r\n\tClimate change and the media are relatively new to the human migration debate, but both issues play important parts, and some interesting discussions are appreciated.
\r\n\t
Our (urban) living environment, composed of material and non‐material components and relations among them, including an infrastructure and other built components, ecosystems, their inhabitants and users (e.g. people, animals, vegetation) and other entities (e.g. various enterprises, cultural and political entities, etc.), is a dynamic, complex system (e.g. [1–3]). In general, such a system is unpredictable (e.g. [4, 5]). It is composed of known invariable components (e.g. macro‐location, general climate conditions, certain elements of the environment in the considered time period, etc.); known variables (those of which we are aware, but their quality or quantity is unknown or variable, e.g. infrastructure, [built] environment, individuals, their habits, their occupations, their routines, etc.); and unknown variables (those of whom we are not aware and/or cannot determine, e.g. daily politics and unpredictable disasters).
In approaching the system from a large scale in certain circumstances, the analysis and simulation of selected aspects within the selected condition limits may appear simple (i.e. it is possible to determine the simple approximations of relations, e.g. linear). However, such an approach in general does not result in appropriate useful results. On the other hand, the determination of very complex relations in the large‐scale analyses may result in very unreliable results and uncontrollable simulations.
Considering the above, an attempt to start with a more profound investigation of the components of the system that are of concern to us and their relations to other components, i.e. to the system, appears reasonable. At that level, relations are more simple (or less complex), and it is more likely that simple approximations result in acceptable outcomes. Yet, the simultaneous monitoring and valuation of higher‐level results (i.e. mass result, larger scale) is important. This calls for the use of the bottom‐up approach, based on small rather than big data, which may help with interpreting or informing big data in spatial statistics (e.g. [6]).
This chapter addresses people‐spatial relationships, their quantifications and qualifications and related measures for bottom‐up evidence‐based and user‐centred urban planning. Based on time quality assessment (TQA), a time‐people‐place‐oriented approach for the evaluation of the quality of living environments, this chapter provides specific types of spatial information about urban environments and challenges the current two‐dimensional land‐use perspective in urban planning with a dynamic and comprehensive perspective, taking into account users, the activities in which they are involved and the environments in which these activities are taking place, analysing three key parameters: time balance, economic balance and time‐quality balance. The chapter shows that the quality of the time spent on a certain activity in a certain place indicates the quality of the living environment. It also shows that the quality of the time spent depends on what a person can afford, and it provides an evaluation of the quality of living environments with a measure of good/bad time. This chapter provides empirical knowledge based on user‐centred small‐scale spatial statistics to support practical guidance for informing decision‐making processes for people‐friendly living environments.
In relation to spatial planning assistance, keeping behaviour patterns in mind, interest has been increasing in the development and implementation of approaches based on information computer technology (ICT) and geolocated social media data (e.g. [7, 8]). However, to be able to talk about the quality of living environments via a time‐people‐place‐oriented approach, first, time as a dimension also has to be applied to non‐transportation activities. Reference [9] addressed the travel‐time ratio and examined the relationship between travel time and stay time (keeping the goal of the travel in mind). Such an approach is particularly useful in the evaluation of the actual temporal scheme of a person\'s routine. However, it does not comment on the quality of the time spent on travelling or on staying. In this respect, the chapter addresses the quality of living (environments) via the quality of time spent within peoples’ daily routines.
The quality of time spent on an activity is a complex function going beyond the quantity of time spent on a certain activity in a certain place. However, it combines the basic economic ability of a profile, the assessment of the conduciveness of the physical environment and the pleasantness of the activity taking place there. Contemporary responsive urban planning on a general level refers to the quality of living environments and well‐being. In relation to the development and current state of the field of approaches towards assessing or measuring quality of living, a variety of comprehensive concepts related to quality of life exist, usually referring to the quantitative social, spatial and economic aspects (e.g. [10–13]). A literature review shows that although quality of life is recognised as a general concern, little consensus has been reached on a definition of quality of life or on the factors/predictors of an individual\'s quality of life (e.g. [14, 15]). In the past decade, the quality‐of‐life concept has also been focussing on well‐being, health and standard of living addressed via softer indicators, such as happiness, life satisfaction and the like [16].
However, despite the fact that many strategic documents (e.g. [17]) presenting fundamental objectives for smart, sustainable and inclusive growth have emphasised the importance of local development towards quality of place and the well‐being of people, quality‐of‐life‐oriented studies still lack a focus on detailed actual and local‐level aspects, which may better interpret or indicate quality of life and living environments. In relation to this, [18] argues that the actual implementation of such objectives in real‐life situations (on a scale of 1:1) is often vaguely realised. In this framework, this chapter introduces the prototype of the TQA approach and shows how the model can work. TQA has been introduced as an alternative approach for assessing the effectiveness of human environments for living [19], using bottom‐up evidence‐based spatial statistics. In city planning and design processes, the TQA of living environments represents a potential universal baseline, where the TQA approach examines relationships between characteristic socioeconomic profiles acting in certain environments.
The current development stage of the TQA approach is characteristic of a clearly stated and well‐developed concept, based mostly on theoretical simulations. A fully fledged investigation was not implemented. The concept foresees that calibration regarding quality of activity follows target‐group questionnaires, interviews or appropriate ways of crowd sourcing (e.g. Web public participation, social networks) depending on the environment where the approach is applied. Similarly, quality parameters and weights used initially follow a combination of expert knowledge (e.g. sociological studies of everyday life, studies addressing placemaking and place attachment, a combination of expert knowledge from the fields of environmental psychology, urban planning and design) and data collected from the relevant target groups. This chapter discusses a new approach and illustrates its applicability to and value mostly for examples that simulate possible real situations. The comments are based on selected cases, theoretically set up and occasionally proven for some territories, knowing their socioeconomic characteristics (source: Statistical Office of the Republic of Slovenia [SURS]; Surveying and Mapping Authority of the Republic of Slovenia [GURS]), place characteristics (e.g. spatial‐site analysis, behaviour‐mapping analysis, GURS) and commuting possibilities for the theoretical target profile, using Michelin or similar portals. To keep the discussion manageable, the simplification of parameters or situations is used.
Three main pillars of input data are relevant for the approach: data related to the user profile, data related to the activity for which the suitability of the area is examined and data related to space. In general, the collected data refer to five binds of information: population, housing, leisure and recreation, services and transport, and they provide a possible examination of:
facilities that examined territories shall provide,
mobility networks that assure accessibility to these facilities and
facilities in correlation with population densities.
The population can be grouped into various groups, based on common crucial characteristics, resulting in segments of the population. One such segment of the population is defined by boundary profiles and characteristic profiles (e.g. central profile, the most representative). Accordingly, it is possible to define the limits of the population of the studied area and the edge conditions of/for such a population within the area. Further, individual profiles are necessary to define, as they can help to describe the population in the studied area. They can be set up from available statistical data or any other relevant source (e.g. questionnaire) regarding demographic and social parameters, such as age, gender, family status, education, occupation, income and the like.
Based on crucial boundary characteristics, variations of individual profiles are designed by logical filters or on the basis of known data about the population of the area of interest. Further, the implementation of the TQA approach builds on the assumption that if boundary profiles are satisfied, all profiles within the studied segment of the population are covered.
To get as thorough of an insight as possible into a segment of the population in the context of this chapter, the daily routines of boundary profiles are important. There are as many routines as there are boundary profiles. However, there can be fewer different routines as there are profiles, as some profiles can have the same daily routines. An analysis of the daily routines of boundary profiles can result in the compatibility of various segments of the population in certain areas, as daily routines may explain similarities in people\'s interests. The implementation of TQA results in the acceptability and quality of places for a particular segment of the population, and it enables an examination of how well a certain place suits this group of people and how well it enables their co‐habitation. The final result of the TQA approach is a time‐quality balance of a profile.
Thus, the key points for any scenario or spatial development defined in this approach are the user profile, activity and space, where three conditions related to the user profile, acting in a certain territory, are analysed:
time balance,
economic balance and
time‐quality balance.
Time balance shows how comfortably the user spends time in his/her (living) environment; how comfortably a segment of the population can live in a certain area, i.e. how a chosen routine is manageable for an individual in the available time frame; and whether a person can achieve necessary and optional activities within the available limits of the time frame (e.g. 24 h/day, within the schedules/opening hours of available capacities for the selected activities). A comparative analysis of more segments of the population shows the abilities of the co‐habitation of various segments of the population in the same area. It also shows if any segment of the population is being disregarded or favoured. This means that the time‐balance category is place dependent. This is closely linked with spatial characteristics (e.g. structure of the place, infrastructure, program, etc.). Time balance is possible to establish when one has a defined profile, routines and belonging space(s). Time balance shows how comfortably time is offered to the user through his/her (living) environment.
The time spent on each action should be shorter or equal to the available time for that action and should be accommodated within the time sequence available for the action:
where
For an illustration, when one does not manage that action in time, the person is late. However, the minimum required condition—although it is not always sufficient—is to do everything required in the entire available time frame (e.g. to do all daily routines in 24 h):
Time‐balance analysis shows a balance of necessary and optional activities. In the situation of assessing the suitability of a neighbourhood for a certain profile, first checking the criteria at the level of time balance is the profile\'s ability to fulfil activities. If the profile is not able to fulfil necessary activities, the neighbourhood is not suitable for it, and if the profile is not able to fulfil optional activities, optional activities must be re‐organised against a new priority list.
Economic balance is a category that represents the subject\'s income and expenses for necessary and optional activities, and a financial framework within which the subject is flexible to be able to perform each of the activities in a certain environment, i.e. whether the selected activities can be afforded per person within a household and whether the incomes and expenses of a household per person enable these activities to be fulfilled.
The basic information addressed is a household\'s incomes and expenses for necessary activities and optional activities. The expenses of a household should not exceed the incomes:
where
Incomes are classified as regular (e.g. salary earned in working time every working day); other regular (e.g. pension, rent); and irregular (e.g. property selling). Expenses are classified as: residential expenses; basic basket expenses (e.g. food, clothes); other necessary expenses (e.g. nursery, school); other optional expenses; and travel expenses for commuting as a part of a daily routine.
Time‐quality balance calculates the time spent in terms of both activity and environment. The component of time‐quality balance shows when a financial situation allows activities to happen; how well the time needed for them has been spent in total; and how much of the entire time taken for all of the activities per day is considered good quality and how much of it is bad quality. Time‐quality balance shows the final quality of the time spent within a routine and reflects on the quality of the living environment in which the profile lives. Thus, with this final parameter, the TQA approach shows whether a segment of the population can live in a certain area and how comfortably:
where
Following the TQA approach, two time‐quality components are proposed:
AC = activity component; SC = space component
therefore
To implement TQA as a universal evaluation tool for quality of place in relation to its usage, behaviour mapping [19] is seen as a key part of the process. This is true especially where behaviour maps extract behavioural evidence into layers of spatial information to provide a better understanding of the individual and the collective patterns of use that emerge in a place.
Behaviour mapping is a method and tool for analysing usage‐spatial relationships originating from the field of environmental psychology in the 1970s of the twentieth century [20]. It is a product of observation and a tool for place analysis and design at the same time, and as such, it represents a means for recording behaviours in a spatial setting and the final results of the observation of dynamic patterns of spatial occupancies, visually expressing structural relations between the characteristics of places and their use(r)s. Behaviour maps can contain broad spectrums of information, from location, type of activity and duration of activity to many other characteristics, depending on the research question, aspects or issues. Therefore, they act as effective media for dealing with the spatial and dynamic patterns of the usage of places. Due to their graphic nature, visualising relationships between various—not necessarily physical—characteristics of places and their users, they can be seen as a valuable tool for improving bottom‐up generated data and for providing new insights for spatial statistics. Practically, they can provide the recognition and understanding of possible or expected uses in places, their frequencies and their intensities, and as such, they may lead towards more effective and responsible planning and design practice and towards the achievement of better quality of living. Knowing actual activities in places and their characteristics in places is important for the identification of quality of everyday living and for directing and stimulating the suitability of territories for occupancy.
Some fundamental conditions need to be met before any recording of behaviour can start. It is necessary to define the area to be observed, to clearly define the types of activities and details about behaviours to be observed, to schedule specific times and their repetitions for observation, and to provide a system of recording, coding, counting and analysing with either a low‐ or high‐tech recording approach. This chapter argues for behaviour mapping as both an analytical tool for monitoring daily routines and as a means of the interpretation of the TQA approach, and by this, it is promoted for the provision of bottom‐up generated datasets as a basis for user‐centred spatial statistics. Behaviour mapping has the capacity to address the social needs, locations, dimensions, frequency, intensity and co‐habitation of activities in places directly. It refers to groups and individuals as well as social‐relations change.
Thus, such behaviour maps can be used to capture the knowledge that brings the indirect insights of usage‐spatial relationships and to visualise abstract notions and essentially the non‐spatial characteristics of physical environments. In relation to TQA, one of the key pieces of information offered is time‐related characteristics. A behaviour map can show two significant temporal dimensions: (1) for how long a certain activity is going on in a certain place and (2) on which day or in what other time‐unit sequence the activity has been taking place. In the TQA approach, behaviour is usually defined by a daily routine but allows the consideration of other situations, e.g. a weekly routine and extraordinary routine.
The challenge of this concept is to shift the understanding about and focus on datasets for city analysis towards people and places. Assisted with behaviour mapping, this alternative approach provides a time‐based perspective on the activities and engagement of people.
Posavje is one of Ljubljana\'s 17 districts; it features a wide range of spatial and living situations, from dense and high residential neighbourhoods to rural, mostly agricultural areas, and it includes a transport point of view supplied by public bus services and the regional railway track. To illustrate the TQA approach, the assessment of quality of living environments via quality of time for a family man was modelled. Time‐quality assessment for the daily routine of a profile living in two different micro‐locations within the same neighbourhood was analysed and simulated. Further, regarding the contemporary demographic situation across Europe, attention was paid to elderly people—one of the vulnerable user groups—assuming that when some settings and arrangements are good for them, it is quite likely that they may suit other users, too. Four different locations within four characteristic neighbourhoods in the area were analysed and simulated (Figure 1).
Case study area.
Time‐quality assessment for the daily routine of a profile living in four different types of locations within the area was simulated using the TQA approach. High‐rise flats that also provide accommodation unit for elderly people by the highway is denoted by the letter a; the area of individual houses by b; high‐rise flats in the centre of the neighbourhood, close to the community centre, by c; and the area of a compact rural settlement by d, where d1 is assigned to the current state of d. The letter F denotes a profile of a working family man with pre‐school children. The simulation examines two micro‐locations in high‐rise flats in the centre of the neighbourhood, close to the community centre, c1 and c2. The letter E denotes the profile of an elderly man; therefore, Ea, Eb, Ec1 and Ed1, respectively, are denotations of one of the possible daily routines of such a person, regarding the location of his home. Examples show daily routines in nice weather during spring or autumn.
The first case (Fc1 and Fc2; Section 3.1) is focused on the procedure of the TQA approach; setting up a profile; and defining and monitoring a routine and time‐balance assessment, economic assessment and time‐quality assessment as a final result of the process. Meanwhile, the second case (Ea, Eb, Ec1 and Ed1; Section 3.2) is focused on the characteristics of the routine of the profile living in different areas within the studied territory and their feasibility regarding the circumstances (Ed1–Ed4).
No absolute measure of quality of living space exists. One always compares two spaces to declare the quality of each, where one or both spaces may be fictive. The quality of one space may be defined in relation to another known or defined quality, whereas the parameters of quality depend on the purpose of the space and/or the user(s) of the space. Something that is important for one user may not be as important for another user or may not apply to other users at all.
The TQA approach extracts the time spent on any activity into the good or the bad portion. The rest of the time, not classified as good or bad, is considered as the indifferent portion of time. In the TQA approach, satisfaction with time is valuated using a scale from -100% satisfaction (complete dissatisfaction) to +100% satisfaction (complete satisfaction), where 0% satisfaction would mean that the user is indifferent to the time spent in a certain space.
To generalise in such a valuation:
a good time is represented by a positively signed percentage of satisfaction;
a bad time is represented by a negatively signed percentage of satisfaction; and
the rest is identified as indifferent time.
This also indicates that a good time and a bad time can neutralize each other, e.g. good time = -bad time (e.g. 1 h of good time + 1 h of bad time = 0).
The measure of quality is the quantity of good time (or bad time if the result is negative) after summation. The sum of the absolute values of the quantity of time (good + bad + indifferent) may not exceed the absolute value of the available time (e.g. 24 h/day).
Further evaluation that introduces time as the universal measure for the quality of environments refers to activities and spaces linked to these two components of time (activity component—FQAC, spatial component—FQSC) by weight (FWAC, FWSC), i.e. how much of an influence each of the components has on the quality of time spent in a place for this certain activity. This thought depends on the profile\'s preferences, which may also depend on affordances (e.g. economic ability). The weight of each quality component describes how much each component contributes to the potential quality of time, e.g. the potential satisfaction with the time spent in the given place. These two parameters finally shape the activity‐place relationship in a daily routine, and they are, for comparative purposes, finally transferred into the coefficient of time quality and time‐quality balance (KTQ and TQ).
In all of the examples referring to the implementation of the TQA approach, the following parameters are assessed and/or calculated:
TSp, time spent (hours, minutes); FQAC, quality of activity component of time (%); FQSC, quality of spatial component of time (%); FWAC, influence of activity component of time (%); FWSC, influence of spatial component of time (%); KTQ, coefficient of time quality; TQ, quality time (hours, minutes).
When implementing the TQA approach, it must be remembered that time balance and economic balance are absolute objective measures, while time‐quality balance is always subjective. Hence, it shows how one place may be better (e.g. provides higher benefit/comfort for the user) than the other and always needs to be commented regarding the context. In this respect, although economic balance represents an absolute value, it is linked to location.
The simulation illustrates activity‐place relations and time‐quality balance (TQ) for a total daily routine for two variations of the same main socioeconomic profile from the same neighbourhood. The initial results are related to the time spent on the activities and the basic qualities of activities and places. Further evaluation introduces time as the measure for quality, referring to activities (activity component of time—FQAC) and places (spatial component of time—FQSC), taking into account the weight (FWAC, FWSC) of each quality component, which describes how much each component contributes to the potential quality of time. The final results are the coefficient of time quality (KTQ) and time‐quality balance (TQ).
For an illustration, a segment of the population is presented. It is defined as an educated man with a permanent job and family. Age, family income and number of children are selected as three key characteristic parameters for setting up boundary profiles of such a segment of the population. The age ranged from the beginning of the carrier (30‐year‐old man) and towards the end of the carrier (55‐year‐old man). Boundaries regarding family incomes are represented by low‐income educated family (2.400 EUR per month) and high‐income educated family (12.000 EUR per month). Boundaries for the number of children are one child and four children. Based on these characteristics, eight combinations of profiles are possible (Table 1).
Discussing the possible daily routines of such eight profiles, generally, two different schedules exist: Those with more children spent more time on preparation activities and on dropping‐off/picking‐up activities. However, the assumption is that their final daily routines differ much more, including the time valuation of journeys among the activities, and the consideration of their working and opening hours.
Parameters of the profile and its minimal time required for necessary activities in a daily routine, excluding commuting.
Earnings | Residentialexpenses | Basicbasket | Other necessaryexpenses | Optionalexpenses | Commuting | Total | Savings | |
---|---|---|---|---|---|---|---|---|
Case 1 [EUR] | 40.000 | 12.000 | 11.500 | 4.400 | 700 | 1.400 | 30.000 | 10.000 |
Case 2 [EUR] | 40.000 | 15.600 | 15.400 | 4.400 | 3.200 | 1.400 | 40.000 | 0 |
Case 3 [EUR] | 40.000 | 4.600 | 15.400 | 4.400 | 3.200 | 1.400 | 29.000 | 11.000 |
Examples of economic balance for three cases of the same profile.
The selected profile, used for an illustration of the TQA approach, is a member of a household characterised by: family with two adults (age 30–55), two children (age 1–15) and incomes (net) of 40.000 EUR/year, i.e. one parent earns 22.000 EUR, while the other earns 18.000 EUR, which equals approximately 11 EUR/working hour for the first and 9 EUR/working hour for the second.
Three characteristic situations are simulated (see Table 2). In the given neighbourhood, the basic level of expenses of such a household would be approximately 30.000 EUR/year. In the case where the family rents their apartment, their expenses are as follows (see case 1, Table 2): 12.000 EUR for residential expenses; 11.500 EUR for basic basket expenses (e.g. food, clothes); 4.400 EUR for other necessary expenses, such as nursery, school or the possession of a family car; 700 EUR for other optional expenses, such as hobbies, extra travel, vacations and extra insurances; and 1.400 EUR for commuting as a part of a daily routine, considering they are using public transport and they manage daily routines within the range of the city public transport area. In this case, the household may save 10.000 EUR/year = (40.000 – 30.000) EUR/year. However, their lives are rather ascetic.
In this case, if the family faced higher expenses (medium level), their earnings would soon become negligible or none. As simulated in Table 2 (case 2), residential expenses are 15.600 EUR (12.000 EUR + 3.600 EUR), i.e. the family strives for better commodities and affords a larger apartment, assuring a room for every child. They increase the budget for basic basket goods to afford higher‐quality products: 14.400 EUR (11.500 EUR + 3.900 EUR). For other necessary expenses, such as nursery, school or the possession of a family car, they spend the same as in case 1, 4.400 EUR. They put more of their budget towards other optional expenses, such as hobbies, extra travel, vacations and extra insurances, 3.200 EUR (700 EUR + 2.500 EUR), and they keep the same budget for travel expenses, 1.400 EUR. In this case, the balance is ±0 EUR/year = (40.000 – 40.000) EUR/year. This case (case 2, Table 2) illustrates the maximum standard that such a family could afford in the given neighbourhood. In the event they are satisfied with a less expensive apartment, they can accrue some savings. This can be achieved by changing the location or some other quality of the residence (e.g. size, building quality). However, this might increase time requirements for daily travel or decrease satisfaction during the time spent at home.
In the case the family owns the apartment (case 3, Table 2), the yearly residential expenses are considerably lower since the main expense (buying a flat) was realized in the past already. For a medium level of expenses, i.e. they spent 40.000 EUR/year, the savings would amount to approximately 11.000 EUR/year, allocating 1.000 EUR/year for the maintenance of their investment. In such a case, the considered family could easily afford a medium level of expenses or even a higher level (e.g. afford a better apartment or a second car). The question is the effect of each improvement on quality of living. The examples show that in the case where the incomes of such a household amount to less than 30.000 EUR/year and they do not have owner status but instead must rent an apartment, they could not afford to live in the given neighbourhood. In the case where they own an apartment, they could live there and even afford a slightly higher level of other expenses. Savings are usually also an important component of the financial security of a household and consequently influence satisfaction. Therefore, the ability of a household to create some savings in a given environment is not negligible.
Simulating time‐quality balance for the same profile, with exactly the same daily routine, living in the same neighbourhood but on the other side, close to the railway line, would show that the time‐quality balance would decrease. This is especially the case if the quality of the spatial component of time for sleeping, which represents a great portion of good quality time, is considered as rather bad. In such a case, instead of having 10 h 5’ (Fc1;
Time quality balance for Fc1 and Fc2.
The profile was defined based on socioeconomic statistical data. The time and economic balance of the profile was assessed as positive. Data on time and activity were collected on the basis of a combination of approaches: field work related to spatial analysis, including facilities and services (e.g. open/green space, recreation, culture, public transport), and accessibility; and a pilot behaviour observation of the selected areas to get an idea of the behaviour patterns of elderly in the area, including the duration of activities in the environment (e.g. how much time they spent coming from A to B, how much time they spent in a local park or library). An interview with an active member of the local community, an elderly person living in a high‐raised flat area, was conducted and included questions about the daily routine there; the environmental, social and economic commodities associated with living there; and the like.
Parameter calibration was done with a combination of discipline tacit knowledge, expert knowledge and target‐group involvement; the space component as a combination of field work, cartographic materials, expert knowledge and target‐group involvement (indirectly with behaviour mapping, directly via interviewing); and the activity component of target‐group involvement (indirectly with behaviour mapping, directly via interviewing).
The results in Tables 4 and 5 indicate that the best living conditions for an elderly person are the areas of b and c, while area a is disadvantageous primarily due to highway pollution (noise, air pollution) and partly due to remoteness regarding the community/neighbourhood centre. Area d is a bit remote, which is significant for agricultural production activities (early morning noise, season noise, smell), a mixed zone of living‐agriculture‐small‐industry activities, relative weakness in the supply of daily goods, poor capacity and poor management of the spatial infrastructure and therefore also traffic safety issues. However, in comparison to area a, the major advantages are direct contact with green areas, slightly better logistics towards the library and local community centre and lower traffic influence.
Ed2, Ed3 and Ed4 are simulations of daily routines of the profile in the case of the degradation of area d (Table 6). Ed2 simulates a situation where the end bus stop is cancelled, so the area is no longer provided with public transport. Ed3 simulates a situation in which the local supply of daily goods (which is of poor quality already) is completely cancelled, whereas Ed4 simulates a situation in which the area is without a bus and a local grocery supply.
Simulated changes indicate a similar decrease of the comfort of the feasibility of the examined routine due to the cancellation of either a bus (Ed2) or a local grocery supply (Ed3). In the case of the cancelation of both facilities, the daily schedule has to be modified, which manifests in time balance (e.g. less socialising and afternoon green‐area walking, more necessary walking [commuting] and resting). In this simulation, the profile finally loses 1 h 15’ quality time. However, in the Ed4 situation, the routine, which includes shopping and library visiting, is feasible only in good weather conditions, while in the cases of Ea, Eb, Ec1 and Ed1, such a routine is also manageable in other weather circumstances.
Time quality balance for Ea and Eb.
Time quality balance for Ec1 and Ed1.
Time quality balance for Ed2, Ed3 and Ed4.
Implementing the TQA approach results in several levels of outputs, i.e. several evidence‐based user‐centred data available to inform the spatial statistics of territories. They are data on time balance, data on economic balance and data on time‐quality balance.
Such data are linked to both locations and profiles. They enable one to compare profiles within different locations in the area or to inform about the suitability of a certain location in the area for various profiles. Further, they indicate a comparative suitability level of a location for living for a chosen profile against some other location for the same profile, as well as the suitability of a location for one profile in comparison to another.
In providing sufficient repeated analyses or simulations (taking into account various circumstances and edge conditions; e.g. weather conditions), such results can be visualised on a behaviour map showing a profile\'s suitability map for living. When more profiles are involved, a suitability map for living of a community with certain characteristics (minimum profile—the weakest link; average profile—general public in the area) in an area is the final output. Moreover, results can also show which profile can reach the minimum satisfaction level at a certain location in the area and the mapping suitability for the weakest profiles of the community, where different profiles are recognised as the weakest at different locations within the studied area.
Information offered by the TQA approach is useful for any kind of place user, from individuals to check locations, e.g. where to live or work, to decision‐makers at various governance levels. The distribution of such information is possible through the upgrade of existing available information systems. Such information is under a constant refinement process referring to two main sources: available geoinformatics and spatial data, and direct and indirect participatory data. TQA as a monitoring or development‐control approach is applicable to authorities and individuals for establishing new developments in a place, searching for measures of improvements, the comparison of different locations for one particular use and the comparison of various measures in a certain location.
This chapter presents and debates a spatial interaction approach for collecting, analysing and monitoring evidence‐based data to assess quality of space for a certain use (activity) and a certain user (profile) via analysis of the quality of time spent on that activity in a particular space or sequence of spaces, using the TQA approach. The TQA approach proposes time as the universal expression and measure of quality of living, using time balance, economic balance and time‐quality balance as the key indicators for calculating the possibility and comfort of living in the given environment. Data as a result of such an approach are linked to locations and user profiles and are therefore useful for the comparison of profiles within different locations of the area, and judgement about the suitability of certain locations in the area for various profiles.
It illustrates activity‐place relations and time‐quality balance (TQ) for the total daily routine for variations of the same main socioeconomic profile from the same neighbourhood. The initial results are related to the time spent on the activities and the basic qualities of activities and places. Further evaluation introduces time as the measure for quality, referring to activities (activity component of time—FQAC) and places (spatial component of time—FQSC), taking into account the weight (FWAC, FWSC) of each quality component, which describes how much each component contributes to the potential quality of time. The final results are the coefficient of time quality (KTQ) and time‐quality balance (TQ).
The applicable value of this approach is in showing the suitability of a certain location for a chosen profile in comparison with some other location for the same profile, or in showing the suitability of a location for one profile in comparison with another. This is especially important in spatial planning and investment decision‐making processes, as simulating a community with certain characteristics represented via a bunch of profiles (e.g., minimum profile—the weakest link; average profile—general public in the area) allows for a comprehensive simulation of living conditions for future residents or other (business) users. In this respect, the TQA approach can be used for searching for measures for improvements in territories, the comparison of different locations for one particular use, the comparison of various measures in a certain location and establishing new developments in a place. The capability of contemporary ICT tools that serve as an interface between place and people can play a significant role in automating data. Especially, monitoring tools consisting of a smartphone application, a set of Web services and cloud computing and storage can provide very informative and rich information about the parameters relevant for the TQA approach. Such technology (e.g. [21]) enables insights into a real bottom‐up understanding of the daily routines and circumstances with which people are involved, and it is worth linking with TQA in the further development of the approach and its implementation.
Food emulsions are produced from two immiscible liquids (usually oil and water), which in the presence of an emulsifier and by applying an emulsification method, can be dispersed one into another. Some typical examples include mayonnaise, salad dressings, sauces, milk, ice cream, and sausages. These systems can be used to encapsulate, protect, and deliver biocompounds, including vitamins, flavors, colorants, and nutraceuticals [1]. Emulsifiers are food additives acting by forming a physical barrier between the oil and water, enabling their compatibilization. Effective emulsifiers must be quickly adsorbed at the oil–water interfaces leading to a rapid decrease in the interfacial tension, preventing droplets aggregation. Moreover, they must generate strong repulsive interactions promoting emulsion stability [2, 3].
Synthetic emulsifiers (e.g., Tweens and Spans) are well-known for their ability to form highly stable emulsions. However, consumers’ preferences for healthy, sustainable and natural lifestyle habits have increased worldwide. Moreover, some studies have reported intestinal dysfunctions caused by synthetic emulsifiers [4, 5]. In this context, natural emulsifiers have emerged as great alternatives to replace their conventional counterparts, namely proteins [6], polysaccharides [7], phospholipids [8] and saponins [9]. Concerning protein-based natural emulsifiers, the most use ones come from animal sources (e.g., whey proteins, caseins, egg protein, gelatin) [10]. However, plant-based proteins have demonstrated to be good alternatives for their replacement in products with dietary restrictions (e.g., lactose-free) and in vegetarian and vegan foods. Moreover, plant-based proteins are more sustainable as they have a lower carbon footprint [11, 12]. Examples include pea [13, 14] and soy proteins [15], which have been reported for emulsions production.
Aligned with natural emulsifiers, Pickering stabilizers (in particular organic-based colloidal particles) are emerging as promising solutions. Pickering emulsions or particle-stabilized emulsions present high resistance to coalescence and Oswald ripening due to the tight fixation of the particles to the droplets surface [16]. Several food-grade particles have been studied, namely particles based on proteins [17], polysaccharides [18], and protein/polysaccharide complexes [19]. Furthermore, natural emulsifiers from microbial origin such as biosurfactants and bioemulsifiers are also potential alternatives to be explored in food emulsions [20, 21].
This chapter covers a bibliographic review focused on the last 10-years on natural emulsifiers and emulsion technology field. Research and market trends are also highlighted, showing the most relevant natural emulsifier families. Basic concepts concerning emulsion production, classification, and stabilization methods are introduced. A special emphasis is given to Pickering emulsions regarding novel trends in food emulsion systems.
According to the Research and Markets report, amidst the Covid-19 crisis, the global emulsifiers’ market is projected to reach US$ 6.1 Billion by 2027, growing at a Compound Annual Growth Rate (CAGR) of 4.8% over the forecast period (2020–2027). Particularly, natural emulsifiers’ area is estimated to get US$ 3.3 Billion, recording a 5.4% CAGR [22]. In agreement, the “Global Food Emulsifiers Market 2020-2027 report” from MarketResearch, foresees a high potential for the plant-based emulsifiers in the global food emulsifiers market [23].
Concurrently, scientific literature corroborates the global food emulsifiers report’s projections. More than 8,000 documents were found using the terms “natural emulsifier*” OR “bioemulsifier*” OR “bio-emulsifier*” OR “biosurfactant*” OR “bio-surfactant*” OR “Pickering emulsion*” searched in title, abstract, keywords and Keywords plus sections using the Web of Science Core Collection (SCI-EXPANDED), in the 2010–2020 period. Excluding documents with early publication and applying the “Food Science and Technology” filter from WOS, 792 documents were found. By removing 4 documents from 2021 in a final manual screening, 788 documents were analyzed using Biblioshiny app from the Bibliometrix-R package (RStudio) [24] and VosViewer software [25]. The survey was performed on April 25th, 2021.
Table 1 presents some of the retrieved 788 documents concerning the application of natural emulsifiers or Pickering stabilizers in emulsion formation/stability, including their use in biocompound delivery systems. Some works regarding the production of bioemulsifiers or biosurfactants by microorganisms were also found [31, 32]. Several studies addressing Pickering emulsions and the use of high-pressure homogenization were identified.
Natural emulsifiers or Pickering stabilizers | Emulsification method | Main target | Reference |
---|---|---|---|
Zein-Chitosan complex particles | High-shear homogenization | Delivery system (Curcumin) | [26] |
Mannoprotein | High-shear homogenization | Formation/Stability | [27] |
Whey protein Gum arabic Lecithin | Dual-channel microfluidization | Formation/Stability | [28] |
Gum arabic Beet pectin Corn fiber gum | High-shear homogenization Microfluidizer | Formation/Stability | [7] |
Ginseng saponins | High-shear/ High-pressure homogenization | Delivery system (Astaxanthin) | [9] |
Wheat gluten nanoparticles (WPN) WPN-xanthan gum nanoparticles | High-shear homogenization | Delivery system (β-carotene) | [29] |
Pea protein microgel particles | High-pressure homogenization | Formation/Stability | [30] |
Studies reporting the use of natural molecules and Pickering stabilizers selected from the retrieved 788 documents of the bibliometric search.
Figure 1a shows the wordcloud from Author’s Keyword. The higher font size indicates an increased frequency of the keyword. Figure 1b also illustrates keyword co-occurrence network analysis; the terms distributed in the same cluster present the higher similarity, in comparison with the terms distributed in different clusters.
(a) Wordcloud from Author’s keywords (100 keywords; minimum frequency of 5); (b) keyword co-occurrence network (9 clusters; Author’s keywords; number of occurrences 5).
“Pickering emulsions” is the most frequent keyword, followed by biosurfactant (Figure 1). Other keywords (e.g., whey protein, sodium caseinate, glycolipid, sophorolipids, rhamnolipids,
These findings substantiate the keyword co-occurrence analysis (Figure 1). 93 keywords (Author’s keywords) were organized in 9 clusters. The number of occurrences indicates the number of documents where the keyword appears. Each circle represents a keyword with at least 5 occurrences, being their areas proportional to the number of occurrences. The clusters are characterized by different colors and their words can be related.
Some clusters present words associated to recent trends in the area of natural emulsifiers. Clusters 1, 6, 8 and 9 refer to “Pickering emulsions” and other inter-related words, including nanoparticles, Pickering stabilization, and some commonly used Pickering stabilizers such as starch granules, cellulose nanocrystals and kafirin. Clusters 1 and 2 comprise terms related to the rheological properties of emulsions, an important parameter in food applications. The words included in clusters 4 and 5 are associated with microorganisms (e.g.,
Cluster 7 and 9 are centered in words related to the biocompounds delivery systems, namely bioavailability/bioaccessibility, controlled release, encapsulation and examples of used biocompounds, such as beta-carotene, curcumin, and vitamin E. Clusters 8 and 9 refer to proteins, phospholipids, saponins and polysaccharides, such as whey protein isolate, soy lecithin,
In a general overview, the analysis showed the progressive interest in natural emulsifiers due to their relevance for the scientific and industrial communities, as well as for the global market. Moreover, Pickering emulsions are emerging as advanced emulsion technologies within future trends in the food industry.
Natural emulsifiers belong to a broad range of chemical families and some main examples are shown in Figure 2. Within each family, aspects such as the used natural source or extraction method can lead to different properties. Therefore, the next sections summarize the most relevant families in the area of natural emulsifiers and their contextualization in the field of food applications.
Representative chemical structures for each emulsifier family.
Phospholipids are amphiphilic molecules, and a main constituent of natural membranes. Their structure comprises a hydrophilic head holding a phosphoric acid (H3PO4), combined with a hydrophobic tail composed by one or two non-polar fatty acids. They comprise groups as glycerophospholipids or sphingolipids, with lecithins (glycerophospholipid) assuming an important role. Phospholipids can be obtained from diverse natural sources, including milk, vegetable oils (soybean, rapeseed or sunflower), egg yolk, meat and fish [36, 37]. Specifically, lecithins are known to be good stabilizers for food emulsions, for example the ones derived from soy or egg yolk are applied in mayonnaise, creams, or sauces [38]. Other phospholipid examples include phosphatidylcholine, phosphatidylglycerol, phosphatidylethanolamine, phosphatidylinositol, phosphatidylserine, phosphatidic acid, sphingomyelin. The amphiphilic character of these compounds supports their capacity to stabilize emulsions. Concurrently to their ability to stabilize emulsions they can act as texturizing agents, thus influencing the organoleptic attributes of the final product [39].
Saponins are a complex family derived from plants, constituted by triterpenes or steroid aglycones linked to glycosyl derived sugar structures [40]. Usually the aglycones involve pentacyclic triterpenoids with oleanolic acid and the sugars moieties comprise rhamnose, xylose, glucose or galactose [41]. Factors conditioning the composition of saponins are their botanical origin and extraction method.
Proteins are molecules resulting from the combination of 21 different amino acids, having diverse properties, including water solubility, which varies depending on their composition [46]. Structurally, the presence of both hydrophobic and hydrophilic amino acids confer an amphiphilic character, allowing them to be absorbed at oil/water interfaces, leading to emulsion stabilization [47]. However, proteins have low surface activity in comparison with conventional emulsifiers. This is attributed to the random distribution of the hydrophilic and hydrophobic groups within the peptide chains, limiting their adsorption. This effect is balanced by the protein film formation around the droplets, leading to stabilization through molecular interactions [48]. Diverse proteins (e.g., whey, casein, soy or faba bean proteins) have been tested in food applications, e.g., emulsions for the controlled release of lutein [49], ѡ-3 oil [50], bioactive hydrophobic compounds [51], fish oil [52, 53] or β-carotene [54]. Their application in final products is still hindered by environmental conditions such as pH, temperature and ionic strength [48]. However, these drawbacks can be surpassed by using more complex formulations, namely by combining proteins with polysaccharides [48] or by chemically modifying the proteins trough grafting with other compounds such as polyphenols [54].
Polysaccharides are biopolymers composed of monosaccharide units such as glucose, fructose, mannose or galactose, bonded by glycosidic bonds. Their structural rearrangement, i.e., type and number of monosaccharides, type of glycosidic bonds, molecular weight, electrical charge, branching degree, hydrophobicity and the presence of other groups (carboxylate, sulfate or phosphate), rule the polysaccharides functional properties such as solubility, rheology, and amphiphilic character, among others [10]. Their amphiphilicity depends on the presence of hydrophobic (glycolipids) and hydrophilic (hydroxyls) groups, being adsorbed at the interface, forming a thick stabilizing layer (e.g., pectins, gum Arabic) [55]. Moreover, non-amphiphilic polysaccharides can contribute to emulsion stabilization due to their thickener role, increasing the viscosity and decreasing oil droplets’ motion (e.g., alginates, carrageenan) [56]. Despite the high number of polysaccharides available in nature, only few are authorized as food emulsifiers in EU, namely alginic acid (E400), gum Arabic (E414), pectin (E440), cellulose and chemically modified celluloses (E460 to E469) [57]. Polysaccharides can be obtained from animal, vegetal, microbial fermentation or marine sources (algae), being their properties mostly dependent on the source and extraction process [10].
Microbial synthetic routes are emerging as valuable sustainable and green alternatives to produce emulsifiers. They generate compounds with low ecotoxicity, biodegradability, stability (pH and salinity) and low critical micellar concentration (CMC), in addition to biological activity, biocompatibility and digestibility [58]. Emulsifiers produced by microorganisms are classified according to their molecular weight. Low molecular weight family includes glycolipids (e.g., rhamnolipids, sophorolipids, trehalose lipids) and lipopeptides (e.g., surfactin, iturin, fengycin) and are referred as biosurfactants. Polysaccharides, proteins, lipoproteins, and lipopolysaccharides belong to the high molecular weight family and are referred as bioemulsifiers [59, 60]. Glycolipids like rhamnolipids and trehalose lipids are mostly produced by bacterial strains like
Emulsions are colloidal systems constituted by two immiscible liquids (oil and water), formed in the presence of an emulsifier, and, usually, by applying an energy input. The emulsifier selection is therefore an important step to reach stability. They can be classified based on the hydrophilic region that correspond to ionic structures (anionic or cationic surfactants), change charge with pH (amphoteric surfactants) or present no charged centers (nonionic surfactants) [69]. Among them, nonionic surfactants are often used in food applications because they are less toxic and less affected by pH and ionic strength changes [70, 71]. The choice of a nonionic surfactant can be based on the hydrophilic–lipophilic balance (HLB) index [72]. This scale (0–20), reflects the changing from hydrophobic to hydrophilic character, that is, a lower HLB value corresponds to a lipophilic surfactant being appropriate to stabilize water-in-oil (W/O) emulsions, whereas a high HLB indicates the ability to stabilize oil-in-water (O/W) emulsions, due to the strong hydrophilic balance [72].
Emulsions can be classified according to their typology and structure. The first refers to the relative distribution of the immiscible phases (oil and water), and the latter refers to the arrangement of the emulsified entities [73]. Considering the typology, they can be classified as simple (O/W and W/O) or double (oil-in-water-in-oil (O/W/O), and water-in-oil-in-water (W/O/W)) emulsions (Figure 3). Examples of O/W emulsions in food systems include products such as milk, sauces, beverages, yogurts, ice-creams, and mayonnaise [74]. W/O emulsions are not so frequent but can be found in butter and margarine [73, 75]. For double emulsions, W/O/W are the most used systems due to their ability to generate reduced-fat products, when compared to O/W emulsions. Moreover, they can serve as base systems to encapsulate and control the release of sensitive water-soluble compounds, such as flavors or bioactive ingredients [16, 75, 76].
Typology of simple and double emulsions.
Regarding structure, emulsions can be classified as macroemulsions (usually called emulsions), nanoemulsions, or microemulsions. These systems present specific physicochemical properties that influence their range of applications [71]. Emulsions and nanoemulsions are thermodynamically unstable systems because their free energy is higher than the one of the individual phases [74, 77]. Thus, considering that all systems tend to their lowest energy state, phase separation will occur. However, due to their kinetic stability, they may remain in a metastable state for a considerable period of time, delaying the phase separation phenomenon. The kinetic stability is governed by two mechanisms, namely the energy barriers between the two states (emulsified and separated phases) and mass transfer between the phases. Therefore, high energy barriers and slow mass transfer processes delay phase separation [78]. By contrast, microemulsions are thermodynamically stable systems because their free energy is lower than the one of separate phases. Thus, they can be formed spontaneously under particular compositions and temperature conditions. In practice, some energy input is needed due to the existence of kinetic energy barriers [71]. Regarding the droplet size, nanoemulsions and microemulsions present droplet sizes <200 nm, whereas emulsions hold sizes between 200 nm and 100 μm [16, 71].
Nanoemulsions and microemulsions are optically transparent or slightly turbid due to their small droplet size, being valuable for applications requiring transparency, such as soft drinks [79]. Comparatively with nanoemulsions, microemulsions require a higher emulsifier content, have a lower particle size, and droplets can assume a non-spherical shape, feature that can be used to differentiate the two systems. Emulsions are typically turbid to opaque and are used in creamy systems such as dairy products [80]. Table 2 provides some application examples for each system addressing natural emulsifiers.
System | Type | Natural emulsifiers | Final applications | Reference |
---|---|---|---|---|
Emulsions | O/W | Whey protein | Ice-cream | [81] |
O/W | Coffee creamers | [82] | ||
W/O/W | Whey, rice and pumpkin seed proteins | Cheese | [83] | |
O/W | Faba bean protein | Tofu and yogurts | [84] | |
O/W | Pectin | Functional foods | [85] | |
O/W | Rhamnolipid | Beverages | [86] | |
O/W | Whey protein, locust bean gum, and iota-carrageenan | Mayonnaise, salad dressings, and sauces | [87] | |
O/W | Modified starch | Dairy products | [88] | |
Nanoemulsions | O/W | Soy lecithin | Fruit juices | [89] |
O/W | Soft foods, creams, sauces, and salad dressings | [90] | ||
O/W | Functional foods and beverages | [91] | ||
O/W | Ginseng saponin | [9] | ||
O/W | Whey protein, gum Arabic, and soy lecithin | [92] | ||
O/W | Modified starch, whey and casein proteins | [93] | ||
Microemulsions | W/O | Soy lecithin | Extraction of edible vegetable oils | [94] |
W/O | Soy lecithin | Functional foods and soft drinks | [95] | |
O/W | Soy lecithin | [96] | ||
O/W | Soft drinks and minced meat | [97] |
Food applications of emulsions, nanoemulsions and microemulsions using natural emulsifiers.
Emulsions are thermodynamically unstable mixtures, characterized by the presence of at least two immiscible phases and an emulsifier that, when provided with enough mixing energy, are able to maintain stability over time [98]. The role of the emulsifier is essential to assure stable long-term properties. In general, emulsifiers are active surface substances, enabling their positioning at the oil–water interface, reducing the interfacial tension, hindering (or delaying) aggregation phenomena [99]. Typically, the hydrophilic part of the emulsifier is located in the aqueous phase, while the hydrophobic tail remains enclosed in the oil phase [82, 100]. During emulsion formation, the surfactant molecules require time to move to the interface, forming a layer to reach the interfacial tension equilibrium, a phenomenon related with their adsorption kinetics [82]. This pattern is dependent on emulsifiers’ nature, taking from minutes (e.g., some saponins) to hours (e.g., some proteins), besides being dependent on environmental conditions (e.g., pH, temperature) [82]. To note that, even emulsions are commonly stabilized by a monolayer structure around the droplets, multilayer structures can also be formed. The multilayer pattern favors the electrostatic and steric repulsion of the droplets, improving stability while providing additional protection to the internal phase [16].
The emulsion stabilization mechanism can differ depending on the nature of the used surfactant. In this context four principal stabilization mechanisms are known, namely electrostatic repulsion, steric repulsion, Marangoni-Gibbs effect, and thin film stabilization mechanisms [101]. The electrostatic repulsion is related to ionic emulsifiers and consists on the formation of an electrical double layer at the droplet’s interface, hindering their approximation. Steric repulsion is characteristic of nonionic and/or polymeric emulsifiers, and droplet’s distance is kept due to the adsorption of the hydrophobic segment by the oil phase [101]. The Marangoni-Gibbs effect preserve emulsions’ structure through the deformation of adjacent droplet’s surface, avoiding their outflow, whereas the thin film stabilization mechanism avail the stability of the emulsion by generating a rigid and viscoelastic film, preventing droplets from destabilization effects [101].
Other factors can condition emulsion’s stabilization mechanism, including the emulsifier content, the oil to water ratio or the preparation conditions (pH or temperature). For example, some phospholipids can have no charge at neutral pH, turning into anionic at acidic media, promoting molecule’s swelling at the interface [100]. Moreover, the surfactant concentration can have also impact, e.g., sunflower lecithin in O/W emulsions, at low contents, create a layer surrounding the oil droplets, while at higher concentrations, the stabilization mechanism changes, producing, concurrently, liposomes that might destabilize the emulsion [10]. Considering amphiphilic polymers, when they are used as emulsifiers, they become positioned at the interface, just like the small molecules, but their ability to create intermolecular interactions can provide additional stabilization effects. Their effect on viscosity can also provide a positive stabilization effect [102]. The high hydrophilicity of most polysaccharides can difficult their emulsifier role, if considering the importance of the emulsifiers’ hydrophilic/lipophilic character to interact with both phases. This constraint can be overcome by either chemical or physical strategies [103]. Namely, the suitability of anchoring hydrophobic groups into the polysaccharide structure can equilibrate the hydrophilic/lipophilic balance, that is the hydrophobisation of emulsifier’s surface. Otherwise, alternative approaches imply the mixture of the polysaccharides with other polymers (co-surfactants) to favor the hydrophilic/lipophilic equilibrium and stabilization role.
Food emulsions can be produced using several methods, classified as low-energy and high-energy processes, as represented schematically in Figure 4. The selection of the most appropriate method and respective equipment is based on the volume to process, characteristics of the initial mixture, emulsion’s physicochemical properties, droplet size, and process costs [104]. In Table 3 a survey of recent works dealing with emulsion production trough different methods and using natural emulsifiers in their pure form or compounded with synthetic emulsifiers is presented. Moreover, their potential to encapsulate bioactives for food industry applications is also described.
Schematic representation of the emulsification process through high- and low-energy methodologies.
Productive method | Emulsion type | Oil phase | Particle diameter | Bioactive compound | Emulsifiers | Reference |
---|---|---|---|---|---|---|
Spontaneous emulsification | O/W | MCT | > 10 μm | — | Sunflower phospholipids | [36] |
Emulsion phase inversion | W/O | MCT and orange oil | > 10 μm | Vitamin E | WPI; SMP; Casein; | [105] |
Phase inversion temperature | O/W | Peppermint oil | < 12 nm | Coenzyme Q10 | Lecithin/Tween 20 | [106] |
High-pressure homogenization | O/W | Paprika oleoresin | <150 nm | — | Soy lecithin; WPC; Gum Arabic | [92] |
Microfluidization | O/W | Fish oil | <150 nm | Omega-3 fatty acids | Sunflower phospholipids | [8] |
Colloid mills | W/O | Rapeseed oil | 4.8 μm | — | WPI; Pectin | [107] |
Ultrasonic homogenizer | O/W | MCT; Palm oil; Soybean oil; Rapeseed oil | 0.5–24.1 μm | — | Soy protein isolate | [6] |
Membrane emulsification | W/O/W | Sunflower oil | 35–320 μm | Magnesium | Starch; Pea protein isolate | [108] |
Microchannel homogenizer | O/W | Soybean oil | 35–47 μm | — | Sodium alginate; Pectin; Gum Arabic; Carboxymethyl cellulose | [109] |
High-speed homogenization | O/W | Soybean oil | 143.5 nm | β-carotene; Eugenol | Lecithin; WPI | [110] |
Studies applying different productive methods using natural emulsifiers or natural/synthetic blends to form emulsions and/or to encapsulate biocompounds for food industry applications.
WPI: Whey protein isolate; WPC: Whey protein concentrate; MCT: medium-chain triglycerides; SMP: Sucrose monopalmitate.
Low-energy methods comprise, spontaneous emulsion, and emulsion phase inversion (e.g., phase inversion composition and phase inversion temperature), which occur due to environmental or composition changes namely temperature, pH, and ionic strength of the formulation [104]. Low-energy approaches are more cost effective than high-energy methods. However, they are limited to certain oils and emulsifiers, requiring also large amounts of surfactants, which is not desirable for many food applications [71]. In the work reported by Komaiko et al. [36], spontaneous emulsification lead to emulsions with large droplet size (>10 μm), comparatively with those produced by high-energy methods (<10 μm). The authors concluded that natural emulsifiers can be used in SE emulsions for applications where fine droplets are not essential (Table 3). By contrast, Mayer et al. [105] concluded that it was not possible to produce nanoemulsions using natural emulsifiers by the emulsion phase inversion method. These limitations imply that even natural-based emulsions can be prepared through low-energy methods, high-energy approaches are needed when natural emulsifiers are used.
High-energy methods generate intensive forces promoting the water and oil phases disruption and their subsequent mixture. High-shear homogenizers are the most used equipment’s for producing emulsions in the food industry. They consist on a rotor-stator or stirrer device able to mix the components at high speeds. Usually, large droplets are produced using this approach (1–10 μm) in comparison to alternative high-energy methods. High-pressure homogenization is also widely used in the food industry, being more effective to reduce the droplet size of a pre-emulsion. Generally, this coarse pre-emulsion is produced by high-shear homogenizers, then subjected to the high-pressure homogenization process. The equipment consists of a high-pressure pump (3–500 MPa) to pass the coarse emulsion through a narrow homogenizing valve, generating intensive disruptive forces (shear and cavitation), breaking down the droplets into smaller ones [80, 81].
Many studies have been conducted using two high-energy sequential methods (high-shear and -pressure homogenizers) to produce emulsions/nanoemulsions with natural emulsifiers [111, 112, 113]. Flores-Andrade and co-workers performed a study with soy lecithin, whey protein concentrate (WPC) and gum Arabic as natural emulsifiers, and paprika oleoresin as the oil phase. The coarse emulsion was produced by a high-speed homogenizer, then treated in a high-pressure homogenizer. O/W nanoemulsions were produced, being WPC more effective to form small droplets (d < 150 nm) than the other tested emulsifiers [92].
Microfluidization is the most effective method for producing emulsions with fine droplets (d < 100 nm). This approach is based on feeding the fluid into the homogenizer, which consists of a mixture chamber with two channels. Intensive disruptive forces are generated when these two fluid streams collide at high speed, breaking larger droplets and intermingling the fluids [3]. As the high-pressure homogenizers, microfluidizers were used after preparing a pre-emulsion by high-shear mixers [42, 114]. Ultrasound technique uses high-intense ultrasonic waves, generating intense shear and pressure gradients. The droplets are disrupted mainly by cavitation and turbulent effects [99, 115].
Currently, high-energy approaches are commonly used in the food industry due to their large-scale production capacity and the possibility to process a wide range of raw ingredients [71]. Although several high-energy emulsification devices are available, high-shear and pressure homogenizers, microfluidizers and ultrasound equipment’s are the most used in the production of natural emulsifiers-based emulsions.
Emulsion stability is an important parameter indicating its ability to resist physicochemical changes over time [116]. For food emulsions, the required stability varies according to the intended final application. For example, short-term stability of minutes to hours, is enough for intermediate food emulsions such as cake batter and ice cream mixtures, while long-term stability is required for long shelf-life products, including mayonnaise and salad dressings [117]. For the latter ones, the development of effective strategies to retard emulsion destabilization implies the identification of the main mechanisms leading to this effect [73].
Emulsion instability can occur due to physical and/or chemical processes. The physical instability is responsible for modifying the emulsion droplets spatial distribution and structure, including gravitational separation (creaming/sedimentation), flocculation, coalescence, and Ostwald ripening phenomena (Figure 5). These effects depend on the emulsion composition and structure, besides the storage conditions, namely temperature variation and mechanical stirring [74, 116]. Moreover, the physical phenomena are interrelated and can influence each other during emulsion storage [77].
Common types of instability phenomena in emulsions.
Gravitational separation is driven by density differences between the droplets and the continuous phase. The droplets are subjected to gravitational forces tending to accumulate in the top (creaming) or in the bottom (sedimentation) of the system. Most edible oils present densities lower than water, favoring creaming in O/W emulsions, whereas sedimentation is usually observed in W/O emulsions [116]. Considering the impact of gravitational forces in the large droplets, the separation usually occurs for emulsions with droplet sizes higher than 100 nm or in a final stage of a sequence of instability phenomena [116]. By contrast, for lower droplet sizes, e.g., nanoemulsions, Brownian motion dominates over gravitational forces. Thus, reducing the droplet size is a suitable strategy to retard gravitational separation, with the emulsifier playing an important role to effectively reduce droplets’ size [2, 74]. Furthermore, the emulsifier’ layers tend to minimize the density difference between the emulsion phases, thus reducing the velocity of gravitational separation. Other strategies include modifying the rheology of the continuous phase or increasing the concentration of the droplets [74, 116].
Ostwald Ripening consists of the increase of the droplets size due to the diffusion of small droplets into larger ones, effect driven by their solubility in the continuous phase. This effect is promoted when the droplet’s size decreases [73], being also influenced by the emulsifiers’ properties. Namely, Ostwald Ripening can be retarded by decreasing the interfacial tension of the phases, favored when small-molecule surfactants are used or when using emulsifiers able to form rigid shell around the droplets. By contrast, emulsifiers prone to solubilize the oil and water phases through the formation of colloidal structures (e.g., micelles) accelerate the Ostwald Ripening [2].
Flocculation and coalescence mechanisms are related to droplets aggregation, effect leading to droplet size increase [74]. In flocculation the association of at least two droplets in an aggregate occurs, whereas in the coalescence, the droplets merge into a larger one [77]. Both phenomena are highly dependent on the selected emulsifier [77, 116], namely their nature and colloidal interactions’ capacity [2].
Pickering emulsions are defined as systems stabilized by solid colloidal particles adsorbed at the oil–water interface in a practically irreversible process, creating a coating around the droplets, either in the form of a single or multiple layer, generating a strong steric barrier providing high stability [118]. In the context of Pickering emulsions, the search for natural-based particles is currently a hot topic to face market demands for novel clean label products (absent of emulsifiers) [119]. Pickering emulsions (Figure 6) are raising high interest in the recent years. They are characterized by a long-term stability and have green connotations due to the absence of conventional emulsifiers. These attributes comply with the recent trends of food industry towards the use of sustainable and healthy technologies [16]. The stability of Pickering emulsions is related with the intrinsic properties of the oil and water phases (e.g., type, oil/water ratio, pH, ionic strength) and of the particle stabilizers (e.g., wettability, particle morphology, size and concentration). Particles presenting a contact angle (θ) below 90° are generally suitable for preparing O/W emulsions, whereas θ values greater than 90° indicate good stabilizers for W/O emulsions. At 90°, the particle is immersed equally in both phases [120].
Schematic representation of a Pickering emulsion putting in evidence the particle stabilizers where θ represent the contact angle.
Regarding natural-based particles, three main typologies of stabilizers can be used, namely nanoparticles, microgels and fibrils. Examples include protein derived stabilizers, namely nanoparticles based on corn zein, and colloidal particles of kafirin and gliadin [118, 121, 122, 123]. Although many polysaccharides have high hydrophilic character, some can include hydrophobic side groups (e.g., beet pectin and modified starch) or even active proteins attached to the surface (e.g., gum Arabic) [120], offering potential to act as Pickering stabilizers. Other polysaccharides widely used to produce Pickering bionanoparticles include chitin, chitosan and cellulose. To overcome particle’s limitations as Pickering stabilizers, the formation of complexes has been also proposed, namely complexes such as polysaccharide-polysaccharide, protein–protein, and polysaccharide-protein [124]. Examples include zein-xanthan [125], and tea water insoluble proteins/κ-carrageenan complexes [126].
In the context of the recent trends in Pickering emulsions, research aiming at finding new biological particles, the use of high internal phase emulsions (HIPPE), and the development of bio-based films from Pickering emulsions are becoming topics of high interest for the development of novel food applications. Table 4 presents an overview of recent works dealing with the preparation of Pickering emulsions based on novel biological particles together with the description of the main results envisaging potential food applications.
Particle materials | Main results | Reference |
---|---|---|
Apple pomace | Smaller particles led to emulsions with smaller droplet size, showing higher stability over time (30 days), in addition to improved physical properties (gel-like samples) and antioxidant activity. | [127] |
Bamboo shoots dietary fiber | The emulsions were stable for 4 weeks avoiding coalescence against pH and ionic strength changes and pasteurization conditions. | [128] |
Chitosan-sodium tripolyphosphate | The emulsions presented good thermal stability, showing potential to be applied as a food delivery system for essential oils. | [129] |
Gliadin-pectin | The emulsion with higher particles content (2%) showed suitable physical stability for 30 days, elastic-solid characteristics and good thermal stability (20–80°C). | [130] |
Hordein-chitosan | The emulsions exhibited good stability during storage (14 days, oil ratio = 0.5 and 0.6) and physical properties (elastic gel-like network). | [131] |
Pea protein | The emulsions with higher particle content showed stability against coalescence over 3 months. | [30] |
Sago starch nanocrystals | The emulsions were stable with no signs of creaming for over 2 months. | [132] |
Soy protein isolate-anthocyanin | The emulsions were reached a cream index of 17%, presenting stability for 7 weeks. They presented improved oxidative stability and resistance to | [133] |
Soy protein isolate-chitosan | Cream index values were very low, and the emulsion presented good stability to a broad range of ionic strength and mild temperature conditions (4–60°C). | [134] |
Tea protein | Emulsions with gel-like properties were produced, presenting no creaming over 50 days. | [135] |
Zein-corn fiber gum | High oil concentrations (oil ratio = 0.5) led to higher stability and the formation of a gel-like structure. | [136] |
Zein-gum arabic | The emulsion showed a high stability against coalescence and Ostwald ripening during 30 days of storage (oil ratio = 0.7). | [137] |
Zein-pectin | The emulsions maintained excellent physical stability for 1 month. In addition, they demonstrated good performance as delivery systems of essential oils. | [138] |
β-lactoglobulin-gum arabic | The particles provided stability against coalescence and Ostwald ripening for up to 12 weeks, in addition to improve chemical stability. | [139] |
Examples of bionanoparticles as Pickering stabilizers. All the systems are of O/W type.
HIPPEs are characterized by having a high volume fraction of internal phase (generally higher than 74%), together with relatively low particles concentration resulting in an extremely compacted droplet’s structure [140]. HIPPEs are becoming a novel approach of increasing interest in the food industry, since it combines diverse advantages, namely a semi-solid texture with the ability to encapsulate high amounts of bioactive compounds [141]. HIPPEs allow to control the droplet size distribution, manipulate the morphology and rheological properties, generally presenting enhanced stability against physical, chemical and microbiological stresses [142]. They are positioned as extremely promising substitutes for foods such as margarine, mayonnaise or ice creams [143, 144]. For example, Liu et al. studied wheat gluten as stabilizer in a HIPPE to develop a novel mayonnaise substitute [145]. They obtained excellent results concerning texture and sensory attributes when compared with commercial products.
Bio-based films made from hydrophilic particles added with hydrophobic compounds is another emerging approach in the scope of new applications developed from Pickering emulsions [146]. These strategies provide the ability to improve the stability of the base materials (hydrophilic), in addition to facilitate the combination with hydrophobic materials (e.g., waxes, fatty oils and oils) leading to systems with enhanced moisture barrier properties [147].
The wide variety of emulsion-based systems using natural emulsifiers makes their applicability attractive for various products, particularly in the food industry. The nature and function of emulsifiers, and the formed emulsion type (e.g., nano/micro-scale, simple or double character) can tailor appearance, sensorial characteristics, and attractiveness of foods. Among their diverse functions, the increasing use of emulsions as functionality carriers should be highlighted. In fact, recent works have demonstrated their potential and versatility for the encapsulation of flavors, and to protect and deliver specific bioactives in foods or beverages, helping to strengthen nutritional balances, and enabling the production of reduced-fat products. A summary of examples addressing new trends of emulsion-based products with potential in the food industry are included in Table 5, with some highlighs provided next.
Emulsion type | Oil phase | Emulsifier | Highlights | Reference |
---|---|---|---|---|
O/W | Vegetable oil | Orange pulp and peel powders | Base emulsions for food applications | [148] |
O/W | Orange essential oil | Pea protein concentrate and soy protein isolate | Encapsulation of flavors for the food industry (powder form) | [149] |
O/W | Sunflower, soybean, MCT, and orange oils | Crude saponins isolated from onion skin wastes | Food nanoemulsions (stable emulsions, except at acidic pH and high ionic strength) | [40] |
O/W | Paprika oleoresin | Whey protein and gum Arabic, and soy lecithin | Food and beverage systems for the delivery of carotenoids | [92] |
O/W | Hemp seed oil | Food nanoemulsions with enhanced nutritional properties | [150] | |
O/W | Almond, mustard, olive, and soyabean oils | Biosurfactants isolated from | Food emulsions with improved antibacterial capacity | [151] |
O/W | Corn and sunflower oils) / | Biosurfactant isolated from | Food emulsions with promising properties for salad dressings | [63] |
O1/W/O2 | O1 – Sunflower; O2 - palm oil | Primary emulsion - gelatin, xanthan gum; Secondary emulsion - solid fat crystals | Oil encapsulation systems for texturizing reduced-fat agents | [152] |
Applications of natural-based emulsifiers in food industry.
Lopes Francisco et al. [149] reported an emulsifying system with encapsulation potential based on commercial pea and soy proteins. The work involved the encapsulation of an orange essential oil rich in d-limonene using a O/W emulsion followed by spray drying to obtain powder microparticles. It was demonstrated the ability of pea and soy proteins to act as emulsifiers in the encapsulation of orange essential oil, getting a slightly higher efficiency if using soy protein as the natural emulsifier. These promising results can help consolidate a platform aiming at developing new protective systems to encapsulate flavors for foods, complying with the increasing demand from this industrial sector for natural-based systems.
At the nanoscale, Flores-Andrade et al. [92] reported the preparation of O/W nanoemulsions by high-pressure homogenization, using amphiphilic biopolymers to stabilize paprika oleoresin, namely whey protein, gum Arabic, phospholipids, and soy lecithin. The results demonstrated the effective oil encapsulation, preserving carotenoids (e.g., lipophilic colorants) from chemical degradation, besides positioning this strategy as an attractive route to design new protective and delivery carriers for bioactive compounds aimed at food and/or beverage products.
The potential of double emulsions was also demonstrated by Cetinkaya et al. [152] that evidenced the reduction of the saturated fat content in O1/W/O2 emulsions prepared by fat crystallization according to a two-stage process. Firstly, the primary O1/W emulsion was prepared using sunflower oil and xanthan gum and gelatin as emulsifiers, which was then stabilized in a second oil phase (palm oil), resulting in a structured O1/W/O2 system. Microstructure examination revealed that the accumulation of fat crystals at the interface contributed to stabilize the internal water phase containing the encapsulated sunflower phase. These complex structures showed potential to directly encapsulate hydrophobic oils and act as texturizing reduced-fat agents, which might be of particular interest for the edible oils industry.
This chapter presents an up-to-date overview of current trends in natural emulsifiers and their application in emulsion technology directed to food applications. For this purpose, first, the evolution of food emulsifiers’ scenario over the last 10 years was analyzed through the Bibliometrix-R package (RStudio) and VosViewer software. This analysis indicated a clear driving force towards using natural emulsifiers and the re-emerging importance of the Pickering emulsions. These facts are expected to impact the market growth following the prospectus of available market analysis. The six main identified families of natural emulsifiers were phospholipids, saponins, proteins, polysaccharides, emulsifiers from microbial sources and Pickering stabilizers. Some of them already find extensive use in practical food applications. However, others, mainly natural-based emulsifiers from microbial sources and Pickering stabilizers, despite their high potential, are still needing research investment and regulation clarification (e.g., related to the use of nanoparticles and the use of microbial strains classified as pathogenic in foods). From a technological perspective, the main concepts related to the typology, production methods, stabilization mechanisms, and instability phenomena were presented. Highlighting the increasing interest in Pickering emulsions, a summary of the most recent applications of these systems, including the so-called HIPPEs and their advantages in reduced-fat products development, was provided. To conclude, an analysis of current trends in food emulsion-based products was discussed, putting in evidence the emulsions increasing role as delivery systems of bioactives to support innovative fortified foods advances and the increasing interest in systems based on double emulsions, which provide the opportunity to combine bioactives of different nature. Overall, the field of natural-based emulsifiers combined with the new trends in emulsion technology can, hopefully, be the basis of a new generation of healthy and nutritious food products.
CIMO (UIDB/00690/2020) and AL LSRE-LCM (UIDB/50020/2020) funded by FCT/MCTES (PIDDAC). National funding by FCT, P.I., through the institutional scientific employment program-contract for Arantzazu Santamaria-Echart and Isabel P. Fernandes. FCT for the Research grants (SFRH/BD/148281/2019 of Samara C. da Silva, and SFRH/BD/147326/2019 of Stephany C. de Rezende). GreenHealth project (Norte-01-0145-FEDER-000042).
The authors declare no conflict of interest.
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The most typical simulation and ground thermal response test models for the vertical ground heat exchangers (GHEs) currently available are summarized. Also, a new GWHP using a heat exchanger with special construction, tested in laboratory, is well presented. The second objective of the chapter is to compare the main performance parameters (energy efficiency and CO2 emissions) of radiator and radiant floor heating systems connected to a GCHP. These performances were obtained with site measurements in an office room. Furthermore, the thermal comfort for these systems is compared using the ASHRAE Thermal Comfort program. Additionally, two numerical simulation models of useful thermal energy and the system coefficient of performance (COPsys) in heating mode are developed using the TRNSYS (Transient Systems Simulation) software. Finally, the simulations obtained in TRNSYS program are analysed and compared to experimental measurements.",book:{id:"5084",slug:"advances-in-geothermal-energy",title:"Advances in Geothermal Energy",fullTitle:"Advances in Geothermal Energy"},signatures:"Ioan Sarbu and Calin Sebarchievici",authors:[{id:"173440",title:"Prof.",name:"Ioan",middleName:null,surname:"Sarbu",slug:"ioan-sarbu",fullName:"Ioan Sarbu"},{id:"176508",title:"Dr.",name:"Calin",middleName:null,surname:"Sebarchievici",slug:"calin-sebarchievici",fullName:"Calin Sebarchievici"}]},{id:"49547",doi:"10.5772/61651",title:"Airborne Magnetic Surveys to Investigate High Temperature Geothermal Reservoirs",slug:"airborne-magnetic-surveys-to-investigate-high-temperature-geothermal-reservoirs",totalDownloads:2657,totalCrossrefCites:4,totalDimensionsCites:6,abstract:"Airborne magnetic survey is an effective geophysical exploration method in terms of coverage, resolution and cost, particularly for area with restricted or difficult ground access. Research studies in New Zealand have shown airborne magnetic surveys can indicate the regions of high reservoir permeability and thermal up-flow of active geothermal systems. However, the method has not been extensively used in the geothermal investigations, probably because the interpretation of airborne magnetic data has so far been seen as difficult and requires a complex quantitative 3D modelling of subsurface magnetisation.",book:{id:"5084",slug:"advances-in-geothermal-energy",title:"Advances in Geothermal Energy",fullTitle:"Advances in Geothermal Energy"},signatures:"Supri Soengkono",authors:[{id:"176580",title:"Dr.",name:"Supri",middleName:null,surname:"Soengkono",slug:"supri-soengkono",fullName:"Supri Soengkono"}]},{id:"64812",doi:"10.5772/intechopen.81157",title:"Geothermal Explorations on the Slate Formation of Taiwan",slug:"geothermal-explorations-on-the-slate-formation-of-taiwan",totalDownloads:1318,totalCrossrefCites:3,totalDimensionsCites:4,abstract:"Currently, over 90% operated geothermal power plants are distributed in the volcanic- or magmatic intrusion-related geological systems. Only a few cases are done in metamorphic terranes, especially on the slate formation. Taiwan is located at the ring of fire and is famous for the young orogenic belt, which has wide distributions of rapid uplifting terranes with few active volcanoes. The metamorphic rocks, for example, schist and slate formations with high geothermal gradients, are occurring in the major mountain range. This chapter introduces the techniques or methods we used for geothermal exploration in the slate formation of the Chingshui geothermal field of Taiwan, where a 3-MW pilot geothermal power plant had been installed in 1983 and operated for 12 years.",book:{id:"7504",slug:"renewable-geothermal-energy-explorations",title:"Renewable Geothermal Energy Explorations",fullTitle:"Renewable Geothermal Energy Explorations"},signatures:"Sheng-Rong Song and Yi-Chia Lu",authors:[{id:"253615",title:"Prof.",name:"Sheng-Rong",middleName:null,surname:"Song",slug:"sheng-rong-song",fullName:"Sheng-Rong Song"},{id:"253623",title:"Dr.",name:"Yi-Chia",middleName:null,surname:"Lu",slug:"yi-chia-lu",fullName:"Yi-Chia Lu"}]},{id:"63548",doi:"10.5772/intechopen.81062",title:"Geothermal Potential of the Global Oil Industry",slug:"geothermal-potential-of-the-global-oil-industry",totalDownloads:1212,totalCrossrefCites:2,totalDimensionsCites:3,abstract:"There are around 40 new geothermal power projects commissioned in each of the last few years. Growth of the market is around 5% annually and current installed capacity is about 13,300 MW with about the same in development in 24 countries. These figures are impressive, but they do not bear comparison with any of the fossil fuels. However, few will realise that the global oil industry has a cryptic geothermal power potential that is equal to the entire current output of the geothermal industry. The oil industry is ageing. Many areas still produce copious quantities of oil, but the oil comes with an unwanted by-product, water. The volume of water produced is typically is 10–20 times that of the oil; and the water is hot—in some places very hot (>100°C). In a recent study we showed that the power depleted oil production platforms of the North Sea’s North Viking Graben produce sufficient hot water to deliver around 60% of the power requirement for each field. A review of global oil and hence water production has enabled us to calculate that power production alone from waste water from producing oilfields could be at least 15,000 MW.",book:{id:"7504",slug:"renewable-geothermal-energy-explorations",title:"Renewable Geothermal Energy Explorations",fullTitle:"Renewable Geothermal Energy Explorations"},signatures:"Jon Gluyas, Alison Auld, Charlotte Adams, Catherine Hirst, Simon Hogg\nand Jonathan Craig",authors:[{id:"258666",title:"Dr.",name:"Jon",middleName:null,surname:"Gluyas",slug:"jon-gluyas",fullName:"Jon Gluyas"},{id:"262369",title:"Dr.",name:"Alison",middleName:null,surname:"Auld",slug:"alison-auld",fullName:"Alison Auld"},{id:"262370",title:"Dr.",name:"Charlotte",middleName:null,surname:"Adams",slug:"charlotte-adams",fullName:"Charlotte Adams"},{id:"262371",title:"Dr.",name:"Catherine",middleName:null,surname:"Hirst",slug:"catherine-hirst",fullName:"Catherine Hirst"},{id:"262372",title:"Prof.",name:"Simon",middleName:null,surname:"Hogg",slug:"simon-hogg",fullName:"Simon Hogg"},{id:"262373",title:"Prof.",name:"Jonthan",middleName:null,surname:"Craig",slug:"jonthan-craig",fullName:"Jonthan Craig"}]},{id:"64027",doi:"10.5772/intechopen.81017",title:"Stages of a Integrated Geothermal Project",slug:"stages-of-a-integrated-geothermal-project",totalDownloads:4230,totalCrossrefCites:2,totalDimensionsCites:3,abstract:"A geothermal project constitutes two big stages: the exploration and the exploitation. Each one has a single task whose results allow defining the feasibility of a geothermal project, until achieving the construction and operation stage of the power generation plant. The first stage contains the area recognition, its limitation to the target, and elimination of external factors until defining a geothermal zone with characteristics to be commercially exploited. The main studies and analysis that can be applied during the exploration stage are listed, and the major indicator to continue with the project or suspend is the prefeasibility report. The major risks in the exploration stage are due to studies that are carried out on the surface; at this stage, the costs can be considered low. The main results of the exploration are the selection of sites to drill three or four initial wells. Each well provides a direct overview of the reservoir: depth, production thicknesses, thermodynamic parameters, and production characteristics. The drilling of three to four exploratory wells is recommended, as far as there is certainty of the feasibility of the project, and the development of the field begins with drilling of sufficient wells to feed the plant. In this stage, the cost increases, but the risks decrease.",book:{id:"7504",slug:"renewable-geothermal-energy-explorations",title:"Renewable Geothermal Energy Explorations",fullTitle:"Renewable Geothermal Energy Explorations"},signatures:"Alfonso Aragón-Aguilar, Georgina Izquierdo-Montalvo,\nDaniel Octavio Aragón-Gaspar and Denise N. Barreto-Rivera",authors:[{id:"258358",title:"Dr.",name:"Alfonso",middleName:null,surname:"Aragón-Aguilar",slug:"alfonso-aragon-aguilar",fullName:"Alfonso Aragón-Aguilar"}]}],mostDownloadedChaptersLast30Days:[{id:"64027",title:"Stages of a Integrated Geothermal Project",slug:"stages-of-a-integrated-geothermal-project",totalDownloads:4236,totalCrossrefCites:2,totalDimensionsCites:3,abstract:"A geothermal project constitutes two big stages: the exploration and the exploitation. Each one has a single task whose results allow defining the feasibility of a geothermal project, until achieving the construction and operation stage of the power generation plant. The first stage contains the area recognition, its limitation to the target, and elimination of external factors until defining a geothermal zone with characteristics to be commercially exploited. The main studies and analysis that can be applied during the exploration stage are listed, and the major indicator to continue with the project or suspend is the prefeasibility report. The major risks in the exploration stage are due to studies that are carried out on the surface; at this stage, the costs can be considered low. The main results of the exploration are the selection of sites to drill three or four initial wells. Each well provides a direct overview of the reservoir: depth, production thicknesses, thermodynamic parameters, and production characteristics. The drilling of three to four exploratory wells is recommended, as far as there is certainty of the feasibility of the project, and the development of the field begins with drilling of sufficient wells to feed the plant. In this stage, the cost increases, but the risks decrease.",book:{id:"7504",slug:"renewable-geothermal-energy-explorations",title:"Renewable Geothermal Energy Explorations",fullTitle:"Renewable Geothermal Energy Explorations"},signatures:"Alfonso Aragón-Aguilar, Georgina Izquierdo-Montalvo,\nDaniel Octavio Aragón-Gaspar and Denise N. Barreto-Rivera",authors:[{id:"258358",title:"Dr.",name:"Alfonso",middleName:null,surname:"Aragón-Aguilar",slug:"alfonso-aragon-aguilar",fullName:"Alfonso Aragón-Aguilar"}]},{id:"64812",title:"Geothermal Explorations on the Slate Formation of Taiwan",slug:"geothermal-explorations-on-the-slate-formation-of-taiwan",totalDownloads:1320,totalCrossrefCites:3,totalDimensionsCites:4,abstract:"Currently, over 90% operated geothermal power plants are distributed in the volcanic- or magmatic intrusion-related geological systems. Only a few cases are done in metamorphic terranes, especially on the slate formation. Taiwan is located at the ring of fire and is famous for the young orogenic belt, which has wide distributions of rapid uplifting terranes with few active volcanoes. The metamorphic rocks, for example, schist and slate formations with high geothermal gradients, are occurring in the major mountain range. This chapter introduces the techniques or methods we used for geothermal exploration in the slate formation of the Chingshui geothermal field of Taiwan, where a 3-MW pilot geothermal power plant had been installed in 1983 and operated for 12 years.",book:{id:"7504",slug:"renewable-geothermal-energy-explorations",title:"Renewable Geothermal Energy Explorations",fullTitle:"Renewable Geothermal Energy Explorations"},signatures:"Sheng-Rong Song and Yi-Chia Lu",authors:[{id:"253615",title:"Prof.",name:"Sheng-Rong",middleName:null,surname:"Song",slug:"sheng-rong-song",fullName:"Sheng-Rong Song"},{id:"253623",title:"Dr.",name:"Yi-Chia",middleName:null,surname:"Lu",slug:"yi-chia-lu",fullName:"Yi-Chia Lu"}]},{id:"49252",title:"Using Ground-Source Heat Pump Systems for Heating/Cooling of Buildings",slug:"using-ground-source-heat-pump-systems-for-heating-cooling-of-buildings",totalDownloads:3857,totalCrossrefCites:4,totalDimensionsCites:15,abstract:"This chapter mainly presents a detailed theoretical study and experimental investigations of ground-source heat pump (GSHP) technology, concentrating on the ground-coupled heat pump (GCHP) systems. A general introduction on the GSHPs and its development, and a description of the surface water (SWHP), ground-water (GWHP), and ground-coupled heat pumps are briefly performed. The most typical simulation and ground thermal response test models for the vertical ground heat exchangers (GHEs) currently available are summarized. Also, a new GWHP using a heat exchanger with special construction, tested in laboratory, is well presented. The second objective of the chapter is to compare the main performance parameters (energy efficiency and CO2 emissions) of radiator and radiant floor heating systems connected to a GCHP. These performances were obtained with site measurements in an office room. Furthermore, the thermal comfort for these systems is compared using the ASHRAE Thermal Comfort program. Additionally, two numerical simulation models of useful thermal energy and the system coefficient of performance (COPsys) in heating mode are developed using the TRNSYS (Transient Systems Simulation) software. Finally, the simulations obtained in TRNSYS program are analysed and compared to experimental measurements.",book:{id:"5084",slug:"advances-in-geothermal-energy",title:"Advances in Geothermal Energy",fullTitle:"Advances in Geothermal Energy"},signatures:"Ioan Sarbu and Calin Sebarchievici",authors:[{id:"173440",title:"Prof.",name:"Ioan",middleName:null,surname:"Sarbu",slug:"ioan-sarbu",fullName:"Ioan Sarbu"},{id:"176508",title:"Dr.",name:"Calin",middleName:null,surname:"Sebarchievici",slug:"calin-sebarchievici",fullName:"Calin Sebarchievici"}]},{id:"49620",title:"Radiogenic Heat Generation in Western Australia — Implications for Geothermal Energy",slug:"radiogenic-heat-generation-in-western-australia-implications-for-geothermal-energy",totalDownloads:2044,totalCrossrefCites:1,totalDimensionsCites:2,abstract:"The chapter reviews heat generation in crystalline rocks and influences on overlying sedimentary basins in Western Australia (WA). Regions of elevated thorium and uranium will cause elevated heat generation, which in turn can cause elevated heat flow. Western Australia hosts several large sedimentary basins with the potential for hot sedimentary aquifers (HSAs). These include the Perth, Carnarvon, and Canning basins. Parts of these basins are underlain by crystalline rocks that contain high levels of heat-generating elements, such as uranium, thorium, and potassium. Also, the Pilbara Craton, which contains both sedimentary and crystalline rocks, that entertains a number of active mines, which may benefit from geothermal energy, is investigated. Further, the southern part of the Perth Basin (Vasse Shelf), which is underlain by crystalline rocks with elevated concentrations of thorium and uranium, is shown to possess higher than usual temperatures. From observations, and geothermal modeling, it is concluded that the Perth Basin has a high potential for medium- to low-temperature geothermal energy developments. In other parts of Western Australia, the Carnarvon Basin has elevated temperatures in artesian groundwater. Heat flow in the Canning Basin is briefly reviewed; this basin has some geothermal potential, but it is far from the major population centers.",book:{id:"5084",slug:"advances-in-geothermal-energy",title:"Advances in Geothermal Energy",fullTitle:"Advances in Geothermal Energy"},signatures:"Mike F. Middleton",authors:[{id:"176416",title:"Dr.",name:"Mike",middleName:null,surname:"Middleton",slug:"mike-middleton",fullName:"Mike Middleton"}]},{id:"66034",title:"Introductory Chapter: Power Generation Using Geothermal Low-Enthalpy Resources and ORC Technology",slug:"introductory-chapter-power-generation-using-geothermal-low-enthalpy-resources-and-orc-technology",totalDownloads:1377,totalCrossrefCites:0,totalDimensionsCites:2,abstract:null,book:{id:"7504",slug:"renewable-geothermal-energy-explorations",title:"Renewable Geothermal Energy Explorations",fullTitle:"Renewable Geothermal Energy Explorations"},signatures:"Basel I. Ismail",authors:[{id:"62122",title:"Dr.",name:"Basel I.",middleName:"I.",surname:"Ismail",slug:"basel-i.-ismail",fullName:"Basel I. 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He is the president of the Travel Medicine Committee of the Pan-American Infectious Diseases Association (API), as well as the president of the Colombian Association of Infectious Diseases (ACIN). He is a member of the Committee on Tropical Medicine, Zoonoses, and Travel Medicine of ACIN. He is a vice-president of the Latin American Society for Travel Medicine (SLAMVI) and a Member of the Council of the International Society for Infectious Diseases (ISID). Since 2014, he has been recognized as a Senior Researcher, at the Ministry of Science of Colombia. He is a professor at the Faculty of Medicine of the Fundacion Universitaria Autonoma de las Americas, in Pereira, Risaralda, Colombia. He is an External Professor, Master in Research on Tropical Medicine and International Health, Universitat de Barcelona, Spain. He is also a professor at the Master in Clinical Epidemiology and Biostatistics, Universidad Científica del Sur, Lima, Peru. In 2021 he has been awarded the “Raul Isturiz Award” Medal of the API. Also, in 2021, he was awarded with the “Jose Felix Patiño” Asclepius Staff Medal of the Colombian Medical College, due to his scientific contributions to COVID-19 during the pandemic. He is currently the Editor in Chief of the journal Travel Medicine and Infectious Diseases. 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Completed the Course Medical Mycology, the Centraalbureau voor Schimmelcultures (CBS), Fungal Biodiversity Centre, Netherlands (2006). International Union of Microbiological Societies (IUMS) Fellow, and International Emerging Infectious Diseases (IEID) Fellow, Centers for Diseases Control and Prevention (CDC), Atlanta, USA. Diploma of Dermatological Scientist, Japanese Society for Investigative Dermatology. Ph.D. of Juntendo University, Japan. Bachelor’s and Master’s degree, Medicine, West China University of Medical Sciences. Chair of Sichuan Medical Association Dermatology Committee. General Secretary of The 19th Annual Meeting of Chinese Society of Dermatology and the Asia Pacific Society for Medical Mycology (2013). In charge of the Annual Medical Mycology Course over 20-years authorized by National Continue Medical Education Committee of China. Member of the board of directors of the Asia-Pacific Society for Medical Mycology (APSMM). Associate editor of Mycopathologia. Vice-chief of the editorial board of Chinses Journal of Mycology, China. Board Member and Chair of Mycology Group of Chinese Society of Dermatology.",institutionString:null,institution:{name:"Sichuan University",institutionURL:null,country:{name:"China"}}},editorTwo:null,editorThree:null},{id:"5",title:"Parasitic Infectious Diseases",coverUrl:"https://cdn.intechopen.com/series_topics/covers/5.jpg",isOpenForSubmission:!0,editor:{id:"67907",title:"Dr.",name:"Amidou",middleName:null,surname:"Samie",slug:"amidou-samie",fullName:"Amidou Samie",profilePictureURL:"https://mts.intechopen.com/storage/users/67907/images/system/67907.jpg",biography:"Dr. Amidou Samie is an Associate Professor of Microbiology at the University of Venda, in South Africa, where he graduated for his PhD in May 2008. He joined the Department of Microbiology the same year and has been giving lectures on topics covering parasitology, immunology, molecular biology and industrial microbiology. He is currently a rated researcher by the National Research Foundation of South Africa at category C2. He has published widely in the field of infectious diseases and has overseen several MSc’s and PhDs. His research activities mostly cover topics on infectious diseases from epidemiology to control. His particular interest lies in the study of intestinal protozoan parasites and opportunistic infections among HIV patients as well as the potential impact of childhood diarrhoea on growth and child development. He also conducts research on water-borne diseases and water quality and is involved in the evaluation of point-of-use water treatment technologies using silver and copper nanoparticles in collaboration with the University of Virginia, USA. He also studies the use of medicinal plants for the control of infectious diseases as well as antimicrobial drug resistance.",institutionString:null,institution:{name:"University of Venda",institutionURL:null,country:{name:"South Africa"}}},editorTwo:null,editorThree:null},{id:"6",title:"Viral Infectious Diseases",coverUrl:"https://cdn.intechopen.com/series_topics/covers/6.jpg",isOpenForSubmission:!0,editor:{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",biography:"Professor Dr. Shailendra K. Saxena is a vice dean and professor at King George's Medical University, Lucknow, India. His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research work has been published in various high-impact factor journals (Science, PNAS, Nature Medicine) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. Dr. Saxena is a fellow of various international societies/academies including the Royal College of Pathologists, United Kingdom; Royal Society of Medicine, London; Royal Society of Biology, United Kingdom; Royal Society of Chemistry, London; and Academy of Translational Medicine Professionals, Austria. He was named a Global Leader in Science by The Scientist. He is also an international opinion leader/expert in vaccination for Japanese encephalitis by IPIC (UK).",institutionString:"King George's Medical University",institution:{name:"King George's Medical University",institutionURL:null,country:{name:"India"}}},editorTwo:null,editorThree:null}]},overviewPageOFChapters:{paginationCount:5,paginationItems:[{id:"81972",title:"The Submicroscopic Plasmodium falciparum Malaria in Sub-Saharan Africa; Current Understanding of the Host Immune System and New Perspectives",doi:"10.5772/intechopen.105086",signatures:"Kwame Kumi Asare",slug:"the-submicroscopic-plasmodium-falciparum-malaria-in-sub-saharan-africa-current-understanding-of-the-",totalDownloads:0,totalCrossrefCites:null,totalDimensionsCites:null,authors:null,book:{title:"Malaria - Recent Advances, and New Perspectives",coverURL:"https://cdn.intechopen.com/books/images_new/11576.jpg",subseries:{id:"5",title:"Parasitic Infectious Diseases"}}},{id:"81821",title:"Pneumococcal Carriage in Jordanian Children and the Importance of Vaccination",doi:"10.5772/intechopen.104999",signatures:"Adnan Al-Lahham",slug:"pneumococcal-carriage-in-jordanian-children-and-the-importance-of-vaccination",totalDownloads:1,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Streptococcal Infections",coverURL:"https://cdn.intechopen.com/books/images_new/10828.jpg",subseries:{id:"3",title:"Bacterial Infectious Diseases"}}},{id:"81813",title:"Schistosomiasis: Discovery of New Molecules for Disease Treatment and Vaccine Development",doi:"10.5772/intechopen.104738",signatures:"Andressa Barban do Patrocinio",slug:"schistosomiasis-discovery-of-new-molecules-for-disease-treatment-and-vaccine-development",totalDownloads:10,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"New Horizons for Schistosomiasis Research",coverURL:"https://cdn.intechopen.com/books/images_new/10829.jpg",subseries:{id:"5",title:"Parasitic Infectious Diseases"}}},{id:"81644",title:"Perspective Chapter: Ethics of Using Placebo Controlled Trials for Covid-19 Vaccine Development in Vulnerable Populations",doi:"10.5772/intechopen.104776",signatures:"Lesley Burgess, Jurie Jordaan and Matthew Wilson",slug:"perspective-chapter-ethics-of-using-placebo-controlled-trials-for-covid-19-vaccine-development-in-vu",totalDownloads:9,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"SARS-CoV-2 Variants - Two Years After",coverURL:"https://cdn.intechopen.com/books/images_new/11573.jpg",subseries:{id:"6",title:"Viral Infectious Diseases"}}}]},overviewPagePublishedBooks:{paginationCount:13,paginationItems:[{type:"book",id:"6667",title:"Influenza",subtitle:"Therapeutics and Challenges",coverURL:"https://cdn.intechopen.com/books/images_new/6667.jpg",slug:"influenza-therapeutics-and-challenges",publishedDate:"September 19th 2018",editedByType:"Edited by",bookSignature:"Shailendra K. Saxena",hash:"105e347b2d5dbbe6b593aceffa051efa",volumeInSeries:1,fullTitle:"Influenza - Therapeutics and Challenges",editors:[{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",biography:"Professor Dr. Shailendra K. Saxena is a vice dean and professor at King George's Medical University, Lucknow, India. His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research work has been published in various high-impact factor journals (Science, PNAS, Nature Medicine) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. Dr. Saxena is a fellow of various international societies/academies including the Royal College of Pathologists, United Kingdom; Royal Society of Medicine, London; Royal Society of Biology, United Kingdom; Royal Society of Chemistry, London; and Academy of Translational Medicine Professionals, Austria. He was named a Global Leader in Science by The Scientist. He is also an international opinion leader/expert in vaccination for Japanese encephalitis by IPIC (UK).",institutionString:"King George's Medical University",institution:{name:"King George's Medical University",institutionURL:null,country:{name:"India"}}}]},{type:"book",id:"7064",title:"Current Perspectives in Human Papillomavirus",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7064.jpg",slug:"current-perspectives-in-human-papillomavirus",publishedDate:"May 2nd 2019",editedByType:"Edited by",bookSignature:"Shailendra K. Saxena",hash:"d92a4085627bab25ddc7942fbf44cf05",volumeInSeries:2,fullTitle:"Current Perspectives in Human Papillomavirus",editors:[{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",biography:"Professor Dr. Shailendra K. Saxena is a vice dean and professor at King George's Medical University, Lucknow, India. His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research work has been published in various high-impact factor journals (Science, PNAS, Nature Medicine) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. Dr. Saxena is a fellow of various international societies/academies including the Royal College of Pathologists, United Kingdom; Royal Society of Medicine, London; Royal Society of Biology, United Kingdom; Royal Society of Chemistry, London; and Academy of Translational Medicine Professionals, Austria. He was named a Global Leader in Science by The Scientist. He is also an international opinion leader/expert in vaccination for Japanese encephalitis by IPIC (UK).",institutionString:"King George's Medical University",institution:{name:"King George's Medical University",institutionURL:null,country:{name:"India"}}}]},{type:"book",id:"7123",title:"Current Topics in Neglected Tropical Diseases",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7123.jpg",slug:"current-topics-in-neglected-tropical-diseases",publishedDate:"December 4th 2019",editedByType:"Edited by",bookSignature:"Alfonso J. Rodriguez-Morales",hash:"61c627da05b2ace83056d11357bdf361",volumeInSeries:3,fullTitle:"Current Topics in Neglected Tropical Diseases",editors:[{id:"131400",title:"Prof.",name:"Alfonso J.",middleName:null,surname:"Rodriguez-Morales",slug:"alfonso-j.-rodriguez-morales",fullName:"Alfonso J. Rodriguez-Morales",profilePictureURL:"https://mts.intechopen.com/storage/users/131400/images/system/131400.png",biography:"Dr. Rodriguez-Morales is an expert in tropical and emerging diseases, particularly zoonotic and vector-borne diseases (especially arboviral diseases). He is the president of the Travel Medicine Committee of the Pan-American Infectious Diseases Association (API), as well as the president of the Colombian Association of Infectious Diseases (ACIN). He is a member of the Committee on Tropical Medicine, Zoonoses, and Travel Medicine of ACIN. He is a vice-president of the Latin American Society for Travel Medicine (SLAMVI) and a Member of the Council of the International Society for Infectious Diseases (ISID). Since 2014, he has been recognized as a Senior Researcher, at the Ministry of Science of Colombia. He is a professor at the Faculty of Medicine of the Fundacion Universitaria Autonoma de las Americas, in Pereira, Risaralda, Colombia. He is an External Professor, Master in Research on Tropical Medicine and International Health, Universitat de Barcelona, Spain. He is also a professor at the Master in Clinical Epidemiology and Biostatistics, Universidad Científica del Sur, Lima, Peru. In 2021 he has been awarded the “Raul Isturiz Award” Medal of the API. Also, in 2021, he was awarded with the “Jose Felix Patiño” Asclepius Staff Medal of the Colombian Medical College, due to his scientific contributions to COVID-19 during the pandemic. 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He obtained a Master’s degree in Public Health and PhD in Public Health and Epidemiology. He has a background in Clinical Medicine and has taken courses at higher diploma levels in public health from University of Transkei, Republic of South Africa, and African Medical and Research Foundation (AMREF) in Nairobi, Kenya. Dr. Kasenga worked in different places in and outside Malawi, and has held various positions, such as Licensed Medical Officer, HIV/AIDS Programme Officer, HIV/AIDS resource person in the International Department of Diakonhjemet College, Oslo, Norway. He also managed an Integrated HIV/AIDS Prevention programme for over 5 years. He is currently working as a Director for the Health Ministries Department of Malawi Union of the Seventh Day Adventist Church. Dr. Kasenga has published over 5 articles on HIV/AIDS issues focusing on Prevention of Mother to Child Transmission of HIV (PMTCT), including a book chapter on HIV testing counseling (currently in press). 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