Released this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
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We wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
IntechOpen is proud to announce that 191 of our authors have made the Clarivate™ Highly Cited Researchers List for 2020, ranking them among the top 1% most-cited.
\n\n
Throughout the years, the list has named a total of 261 IntechOpen authors as Highly Cited. Of those researchers, 69 have been featured on the list multiple times.
\n\n\n\n
Released this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\n\n
We wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
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1. Introduction
Plate fin-and-tube heat exchangers with oval tubes attract the broad scientific interest due to its large thermal efficiency, significant heat transfer rate between the mediums and compact shape [1-10]. The heat exchangers of this type are widely used in industrial plants and installations, as air-coolers, convectors for home heating and waste heat recovery for gas turbines. The large thermal efficiency is achieved by using the external fins, fixed at the oval tubes of the heat exchanger [1-3]. Mostly, fin-and-tube heat exchangers operate in the cross-flow arrangements. A liquid (water or oil) flows through the tubular space of the heat exchanger, and gas (air, flue gas) flows across the intertubular space of the heat exchanger. Due to the use of external fins, a heat transfer rate increases when compared with tubes without fins. Moreover, the application of the oval tube shape reduces the pressure drop and improves heat transfer conditions on the gas side when compared to the circular shape [4-14, 17]. Since plate fin-and-tube heat exchangers operate in a cross-flow arrangement with the complex path of gas flow, hence in order to determine the velocity field and heat transfer characteristics, the numerical methods must be used [15-16, 18-25]. For the gas flow, with the use of the commercial CFD codes (ANSYS CFX [31], FLUENT), it is possible to calculate the local values of heat transfer coefficient. However, it is impossible to incorporate these values into the analytical formulas, which allow determining the overall heat transfer coefficient. These formulas are fundamental when designing cross-flow heat exchangers and use the average not local values of heat transfer coefficient. Therefore in this study authors present different methods for determination of the average heat transfer coefficient for gas flow in a plate fin-and-tube heat exchanger using the CFD simulations. The values of the heat transfer coefficient obtained using the heat transfer formulas for the Nusselt number, determined with the CFD simulations, can be directly implemented in the thermal designing procedure of the cross-flow heat exchangers. The results of the numerical computations will be validated experimentally, using the procedures described in [14, 17, 20].
The numerical studies of the performance of plate fin-and-tube heat exchangers encounter difficulties in the proper prediction of the total gas side temperature difference. This problem occurs, because of the flow maldistribution of mediums flowing through the heat exchanger and thermal contact resistance between the fin and tube. The thermal contact resistance, which can significantly reduce the thermal performance of heat exchange apparatus, is difficult to determine [15, 19]. It is considerable when the oval tubes are inserted into the holes, which are stamped in metal strips. Then, the tubes are expanded to create the so-called interference fit. Since the gap exists between the fin and tube, the corrosion residuals can cumulate within the gap, leading to the decrease in heat transfer ability. It should be noted, that the direct investigation of thermal contact resistance is difficult to conduct. Therefore, the alternative methods are needed. This study discusses the alternative approach to determining the thermal contact resistance between fin and tube, based on the CFD simulation and experimental data. Moreover, the methods for determining the heat transfer coefficient correlations for the air side are also presented.
2. Test facility – fin-and-tube heat exchanger with oval tubes
Figure 1 presents the scheme of a car radiator, for which the heat transfer coefficients will be determined [19].
Figure 1.
Flow scheme of two-row car radiator with two passes: 1 – inlet manifold, 2 – intermediate manifold, 3 – outlet manifold, 4 – second row of oval tubes, 5 – first row of oval tubes, 6 – plate fin.
The heat exchanger is used for cooling the spark ignition engine with a cubic capacity equal to 1, 580 cm3. Hot water, which flows inside the aluminum tubes of the heat exchanger, is cooled down by the air flowing across the intertubular space.
The two-pass /two-row fin and tube heat exchanger is considered. The following characteristics are given:
Total number of tubes: 38, including 20 tubes in the first pass and 18 tubes in the second
The tube length is Lt = 0.52 m.
The radiator width, height, and thickness is equal to 520 mm, 359 mm and 34 mm, respectively
The aluminum (k = 207 W/(m K)) oval tubes of outer diameters dmin = 6.35 mm and dmax = 11.82 mm, respectively, with thickness of δt = 0.4 mm are used
Total number of plate fins (359 mm height, 34 mm width and 0.08 mm thickness) along the tube length is 520
The fin pitches in the perpendicular and longitudinal directions to the air flow are as follows: p1=18.5 mm p2=17 mm (Fig. 2, [19])
Figure 2.
Scheme of the narrow air flow passage across the car radiator.
The path of the water flow is U-shaped, this means that the water reverses in the intermediate manifold. In the first pass (upper), the hot water with temperature T’w flows from the inlet header (1) thround the two rows of the oval tubes, with the length Lt = 0.52 m. Then, in the intermediate header (2), the mixing of the water streams from the first (4) and second (5) row occurs. The intermediate temperature of the water is equal to T”w. Next, the water reverses and flows into the two rows of the tubes located in the second (lower) pass. Finally, the liquid, cooled down to temperature T’’’w flows out of the heat exchanger through the outlet manifold (3). The air with inlet temperature T’a flows in the normal direction to the both rows of the finned tubes. After the first and second row, air temperature is T”a and T’’’a, respectively (Fig. 1). The plate fins (6) are used to enhance the heat transfer from the air side.
For the CFD calculations presented in this paper (section 4), the flow in a narrow passage formed between two consecutive fins is considered.
3. Experimental methods of determining the air-side heat transfer coefficient in fin-and-tube heat exchanger
The experimental-numerical method for determining the average air-side heat transfer coefficient was described in details in ref. [14, 17]. Moreover, in ref. [17], the detailed list of measurement points, used in this work, is presented. The experimental-numerical method involves the performance tests of a car radiator (Fig. 1) and allows to obtain the formulas for the Nusselt number for the air and water flows. During the measurements the inlet and outlet air temperatures (T’a and T’’’a), the inlet and outlet water temperatures (T’w and T’”w), the volumetric mass flow rate of water V˙w, and the inlet velocity of the air w0, are determined. The following change ranges of T’a, T’’’a, V˙w, T’w, T’”w and w0 were examined:
T’a = 12.5 ºC – 15 ºC,
T’’’a = 38.51 ºC – 57.66 ºC,
V˙w = 865.8 dm3/h – 2186.40 dm3/h,
T’w = 61.0 ºC – 71.08 ºC,
T’’’w = 49.58 ºC – 63.83 ºC,
w0 = 1 m/s – 2.2 m/s.
The value of the experimental heat transfer coefficient ha,ie for the air flow is determined based on the condition that the calculated outlet temperature Tw,i\'\'\'(ha,ie) of water must be equal to the measured temperature (Tw,i\'\'\')e, where i=1,..., n is the dataset number. The following non-linear algebraic equation must be solved for each dataset to determine ha,ie :
(Tw,i\'\'\')e−Tw,i\'\'\'(ha,ie)=0,i=1,..,nE1
\n\t\t\t
where n is the number of datasets. This study employs the mathematical model of the heat exchanger developed in [11] to calculate the water outlet temperature Tw,i\'\'\' as a function of the heat transfer coefficient ha,ie. The heat transfer coefficient for the air flow ha,ie is determined by searching for such a preset interval that makes the measured outlet temperature of water (Tw,i\'\'\')e and the computed outlet temperature Tw,i\'\'\' the same. The outlet water temperature Tw,i\'\'(ha,ie) is calculated at each search step. Next, a specific form is adopted for the formula on the air-side Colburn factor ja=ja(Rea), with m = 2 unknown coefficients. The least squares method allows to determine the coefficients x1, x2 under the condition:
Smin=∑i=1n[ja,ie−ja,i(x1,x2)]2=min,m≤nE2
\n\t\t\t
where:
ja=Nua/(ReaPra1/3)E3
\n\t\t\t
is the air Colburn factor and Pra\n\t\t\t\t= μa\n\t\t\t\tcpa\n\t\t\t\t/ ka is the air Prandtl number. The Nua\n\t\t\t\t= ha\n\t\t\t\tdh\n\t\t\t\t/ ka and Rea\n\t\t\t\t= wmax\n\t\t\t\tdh\n\t\t\t\t/νa are the air Nusselt and Reynolds numbers, respectively. The velocity wmax is the air velocity in the narrowest free flow cross-section Amin. The symbol ja,ie is the experimentally determined Colburn factor, and ja, i is the j-factor calculated with the approximating function for the set value of the Reynolds number Rea, i. The Colburn factor ja is approximated by a power-law function:
ja=x1Reax2.E4
\n\t\t\t
The unknown coefficients x1 and x2 are determined by the Levenberg-Marquardt method [35], using the Table-Curve program [36]. Combining Equations (3) and (4) one gets:
Nua=x1Rea(1+x2)Pra1/3.E5
\n\t\t\t
The wmax air velocity in the narrowest cross-section of flow Amin is defined as:
wmax=sp1Amin(T¯a+273.15T\'a+273.15)w0,E6
\n\t\t\t
where Amin is
Amin=(s−δf)(p1−dmin).E7
\n\t\t\t
The equivalent diameter for the air flow passage dh is [17, 18-19]:
dh=4AminLtAf+Ae,E8
\n\t\t\t
where the fin surface of a single passage Af is:
Af=2⋅2(p1p2−Aoval)=(4p1p2−πdmindmax),E9
\n\t\t\t
the tube external surface between two fins Ae is:
Ae=2⋅Po(s−δf).E10
\n\t\t\t
For the given parameters of the air-flow passage, the equivalent hydraulic diameter is dh = 0.00141 m. The arithmetic average air temperature T¯a taken from the inlet air temperature Ta\' and the outlet air temperature Ta\'\'\' is used to evaluate the thermal properties.
Air-side heat transfer correlations found in this chapter will be compared with the correlations of Kröger [37, 38].
The air-flow Nusselt number correlations, determined via the measurements, are listed in Table 1 [19, 20]. These correlations are paired with the water-flow heat transfer formulas, given in the literature [39- 41]. The correlations presented in Table 1 were employed to determine the outlet temperature of water Tw,i\'\'\' using the heat exchanger model [11].
Nusselt number formulas for the air flow Nua obtained from the measurements
The water flow criteria numbers are: Nuw\n\t\t\t\t= hin\n\t\t\t\tdt\n\t\t\t\t/kw and Rew\n\t\t\t\t= ww\n\t\t\t\tdt\n\t\t\t\t/νw. The friction factor ξ is defined as:
ξ=1(1.82logRew−1.64)2=1(0.79lnRew−1.64)2E11
\n\t\t\t
The mean water velocity in a single tube – ww is calculated using the total volumetric flow rate V˙w as follows:
ww=V˙w/(ntpAw,in),E12
\n\t\t\t
where ntp is the number of tubes in a single pass of the heat exchanger and Aw, in is the cross-sectional area of the flow related to one tube.
The water-flow equivalent hydraulic diameter dt is calculated as
dt=4Aw,inPin,E13
\n\t\t\t
where Pi denotes the oval perimeter (refered to inner tube wall). In this study, the water side hydraulic diameter dt is 0.00706 m.
4. Determining of the air-side heat transfer coefficient using CFD simulations
The CFD simulations [32] were performed to model the heat and fluid flow processes in the air-flow passage, shown in Fig. 2. As a result, the air temperature and velocity are determined. Moreover, with the application of a conjugate heat transfer treatment, the wall temperature of fin and tube are calculated. A similar modeling approach for the gas flow in fin-and-tube heat exchangers was used in papers [15, 18-20]. The approach allows to simplify the computational domain and reduce the computational costs. In this study, the CFD software ANSYS CFX - release 13.0 [31] was used. The phenomenon of air flow across the passage is complex e.g. flow is turbulent at the heat exchanger inlet and laminar between the fins. Hence, the SST turbulence model with Gamma-theta transitional turbulence formulation [33, 34] is used in computations. The model allows to study at the same time both the laminar and turbulent flows.
The element based finite volume method is used to discretize the differential governing equations. The coupled solver is used for the momentum and continuity equations. The Rhie-Chow interpolation scheme with the co-located grid is applied for pressure. The so-called “high resolution” scheme is used to discretize the convective terms [31].
Fig. 3 shows the discrete model and the applied boundary conditions. The model consists of three heat transfer domains: air (1), fin (2), and tube (3). The inlet boundary condition, where the values of air velocity w0 and temperature T’a are prescribed, is denoted as (I). At the outlet boundary (II) the pressure level was held constant at 1 bar. At the inner tube surface (III) the convective boundary condition is applied to model the heat transfer from the water to the tube wall. The water-side heat transfer coefficient hin was determined from the experimental correlation for Nuw given in Table 1. The bulk temperature of the water T¯w flowing through the tube is calculated as the arithmetic average of the measured temperatures: T ’w and T ’’’w.
The thermal resistance between between external tube surface and fin Rtc was set at location (IV). The symmetry boundary condition is applied at the location of (V) in Fig. 3.
Figure 3.
Flow passage studied during the computations: 1 –air, 2 – fin, 3 – tube; boundary conditions: I – inlet, II – outlet, III – convective surface, IV – solid\\solid interface (thermal contact resistance), V – symmetry.
The numerical mesh, shown in Fig. 3 was used in the computation (the number of nodes: 452917, the number of elements: 404560). The grid independence tests were performed for the mass averaged outlet air temperature. Refining this numerical model does not lead to the relative change in the obtained results more than 0.1 %. The global imbalance of mass, momentum and energy equations were less than 0.1%. The boundary flow region computational accuracy was controlled by the so-called y+ value which was less than 3 in the present computations.
The CFD simulation results, obtained for the following parameters: w0 = 0.8 m/s, T’a = 14.98 ºC, hw = 1512 W/(m2·K), Tw =73.85 ºC, Rtc = 0 (m2·K)/W are presented in Fig. 4 [19].
Figure 4.
The results of test CFD simulation: a) air temperature distribution at the symmetry plane between two neighboring fins b) fin temperature c) air velocity distribution at the symmetry plane between two neighboring fins.
The temperature variations for the air and tube are shown in Fig. 4a. The air temperature is determined at the middle plane between fins. Figure 4b shows fin surface temperature while Figure 4c plots the air velocity distribution. The considerable increase of air temperature can be observed in the first tube row. The increase is larger compared to the second tube row (Fig. 4a). Also, the temperature difference between the fin surface and air is larger in the first row than in the second. Fig 4a and 4b reveals that the temperature difference between the fin surface and fluid is large in the entrance region, what in turn increases the heat flow rate. The efficient heat transfer at the inlet section is the main reason of the significant heat flow rate transferred from water to air in the first row of tubes.
In the existence of the low velocity region between the tubes along the symmetry plane, where the wake behind the upstream tube is bounded by the stagnation on the downstream one (Fig. 4c), the fin temperature (Fig. 4b) in the second tube row is high. Due to the recirculation zones the air entrapped in the vortices is heated almost up to the fin temperature (Fig. 4a). In this region the heat flow rate is close to zero, since the temperature difference between the fin surface and recirculating air is close to zero [19].
The presence of two dead-air zones near the tubes located in the second row decrease the heat flow rate from the second tube row to air. The average heat flux q at the outer tube surface on the length of one pitch s between two y coordinates: y¯n and y¯n+1 (Fig. 5) can be calculated as [19]:
dAo -the elemental surface area on the outer surface of the oval tube,
dAc - the elemental surface area on the contact surface between fin and tube,
qo - the heat flux from the outer tube surface to the air across the elemental surface dAo,
qc - the heat flux from the outer tube surface to the fin base across the elemental surface dAc,
y¯ - the vertical distance from horizontal plane passing through the center of the oval tube to the elevation of the point situated on the tube outer surface.
Figure 5.
The outer surface of oval tube (grey elements) and the contact surface between fin and tube (red elements).
The variation of outer surface heat flux with the direction of air flow, is presented in form of dimensionless coordinate ξ,
ξ=−2y¯dmaxE15
\n\t\t\t
The symbol y¯ denotes a distance in the vertical direction between the horizontal plane passing through the oval gravity center ‘0’ and the point located at the outer surface of the tube wall. Figure 6 [19] shows the variation of the heat flux q with the dimensionless major radius ξ of the oval tube for the first and second tube rows.
Figure 6.
The variations of heat flux q on the outer surface of tube wall for the first and second row.
The heat flux q reaches its highest value equal to q = 4.72 104 W/m2 in the first row at the inflow surface of the oval profile (ξ = -1), i.e. front stagnation point. In the area of the rear stagnation point (ξ = 1), the considerable heat flux decrease can be observed in both the first and second tube row. In the rear stagnation point on the tube in the first row, the heat flux is only q = 2.04 103 W/m2.
The heat transfer is more efficient in the first row of tubes, than in the second. The mean (area-weighted) values of heat flux in the first and second tube row are: q¯I = 2.19 104 W/m2 and q¯II = 5.62 103 W/m2, respectively. Thus the average value falls almost four times.
In subsections, 4.1 and 4.2 two methods of determining the air-side heat transfer coefficient are presented. The first considers the application of the analytical model of fin-and-tube heat exchanger while the second allows determining the air-side heat transfer coefficient directly from CFD simulations.
4.1. Determination of the gas-side heat transfer coefficient using the analytical model of fin-and-tube heat exchanger and CFD simulation results
The CFD calculations allow to determine the temperature and heat flux distributions in heat transfer domains. It should be noted that the local and average heat transfer coefficients are difficult to determine due to the unclear definition of fluid bulk temperature. From the definition the local heat transfer coefficient is calculated as a ratio of the local heat flux and difference between the fin surface temperature and air temperature (averaged in the reffered flow cross-section). In the case that the average temperature of the air is calculated as the arithmetic mean of the inlet and outlet temperature, the fin surface temperature at the inlet section of a channel formed by the fins is lower than the air mean temperature and then the calculated local heat transfer coefficient can be negative. This is due to a large change in air temperature with the flow direction. Another possibility of determining the average heat transfer coefficient is to calculate first the local distribution of the heat transfer coefficient and then its average value. Nevertheless, this method encounters difficulties in evaluating the local mass-averaged temperature of the air (air bulk temperature) due to the different directions of air flow in the duct between the fins (in vicinity of flow stagnation zones).
A method for determining heat transfer coefficient [18], presented in this study, aims to avoid defining the bulk temperature of air, local or average for the entire flow passage. The method is appropriate for determining the average heat transfer coefficient using the analytical solution for the temperature distribution of air flowing through the two row fin-and-tube heat exchanger. The method is compatible with experimental predictions of heat transfer correlations.
The mean heat transfer coefficient on the air side is determined from the condition that the air temperature increase over two rows of tubes, is the same for the analytical method and for the CFD calculations (Fig. 7a) [19]. To compare the air temperature difference in the heat exchanger, the inlet and outlet air temperatures obtained from the CFD simmulations should be mass weighted over the inlet and outlet cross-sections. From the comparison of the difference of the air mass averaged temperatures between the inlet and outlet cross-sections with analytical temperature difference, the average heat transfer coefficient on the air side is computed. The analytical model assumes that the air side heat transfer coefficient is constant. Fig. 7b depicts the positions of evaluation planes used in the CFD simulations to determine the mass-weighted air temperatures.
Figure 7.
Cross flow heat exchanger with two rows of tubes: a) air flow passage used in analytical model, b) evaluation planes for mass averaged temperatures T’a, T’’a, and T’’’a used in CFD simulations.
The average heat transfer coefficient ha on the tube and fin surface is determined from the condition that the total mass average air temperature difference ΔT¯to,CFD computed using ANSYS CFX program is equal to the air temperature difference ∆Tto (Rtc, ha) calculated from an analytical model
ΔTto(Rtc=0,ha,CFD)−ΔT¯to,CFD=0E16
\n\t\t\t\t
The total air temperature difference ∆Tto is
ΔTto=Ta\'\'\'−Ta\'=ΔTI+ΔTIIE17
\n\t\t\t\t
where ΔTI=T\'\'a−T\'a and ΔTII=T\'\'\'a−T\'\'a is the air temperature increase over the first and second tube row, respectively (Fig. 7a).
The average heat transfer coefficient ha over two rows of tubes is calculated by solving equation (16). This study assumes the same water temperature Tw in the first and the second tube. This small temperature difference has insignificant influence on the average heat transfer coefficient ha. Furthermore, the water temperatures are assumed as constant along the tube length. Under these assumptions, the following differential equations with appropriate boundary conditions describe the air temperature [19]
dTa(yI+)dyI+=NaI[Tw−Ta(yI+)]E18
\n\t\t\t\t
Ta|yI+=0=T\'aE19
\n\t\t\t\t
dTa(yII+)dyII+=NaII[Tw−Ta(yII+)]E20
\n\t\t\t\t
Ta|yII+=0=T\'\'aE21
\n\t\t\t\t
Solving the initial-boundary problems (18-19) and (20-21) yields
Ta(yI+)=Tw+(T\'a−Tw)e−NaIyI+E22
\n\t\t\t\t
Ta(yII+)=Tw+(T\'a−Tw)e−(NaI+NaIIyII+)E23
\n\t\t\t\t
where
NaI=UoIAo/(m˙acpa),NaII=UoIIAo/(m˙acpa)
\n\t\t\t\t
The symbols m˙a and A denote the air mass flow rate and the outer surface area of the bare tube, respectively. The overall heat transfer coefficient referred to surface area Ao can be expressed as [15, 19-22]:
Uo=1AoAin1hin+2AoAin+Aoδtkt+1h¯aE24
\n\t\t\t\t
with: Ain – area of the inner tube surface, δt - the thickness of tube wall, kt - the thermal conductivity of the tube, hin - the water side heat transfer coefficient. The equivalent air-side heat transfer coefficient h¯a referred to the tube outer surface area Ao is defined as:
The unknown coefficients in the function (26) were estimated by the Levenberg – Marquardt method using a commercial software Table Curve 3d version 4.0 [36]. The coefficients appearing in the function ηf (Rtc, ha) are shown in Table 2 [19].
\n\t
\n\t
\n\t\n\t\t
\n\t\t\t
\n\t\t\t\tCoefficient\n\t\t\t
\n\t\t\t
\n\t\t\t\tValue\n\t\t\t
\n\t\t
\n\t\n\t
\n\t\t
\n\t\t\t\n\t\t\t\tc1\n\t\t\t\t\n\t\t\t\n\t\t
\n\t\t
0.999
\n\t
\n\t
\n\t\t
\n\t\t\t\n\t\t\t\tc2\n\t\t\t\t\n\t\t\t\n\t\t
\n\t\t
3.100
\n\t
\n\t
\n\t\t
\n\t\t\t\n\t\t\t\tc3\n\t\t\t\t\n\t\t\t\n\t\t
\n\t\t
4.850
\n\t
\n\t
\n\t\t
\n\t\t\t\n\t\t\t\tc4\n\t\t\t\t\n\t\t\t\n\t\t
\n\t\t
2.100·10-3\n\t\t
\n\t
\n\t
\n\t\t
\n\t\t\t\n\t\t\t\tc5\n\t\t\t\t\n\t\t\t\n\t\t
\n\t\t
9.626
\n\t
\n\t
\n\t\t
\n\t\t\t\n\t\t\t\tc6\n\t\t\t\t\n\t\t\t\n\t\t
\n\t\t
-1625.550
\n\t
\n\t
\n\t\t
\n\t\t\t\n\t\t\t\tc7\n\t\t\t\t\n\t\t\t\n\t\t
\n\t\t
-3192.846
\n\t
\n\t
\n\t\t
\n\t\t\t\n\t\t\t\tc8\n\t\t\t\t\n\t\t\t\n\t\t
\n\t\t
-6.763
\n\t
\n\t
\n\t\t
\n\t\t\t\n\t\t\t\tc9\n\t\t\t\t\n\t\t\t\n\t\t
\n\t\t
-2.013
\n\t
\n\t
\n\t\t
\n\t\t\t\n\t\t\t\tc10\n\t\t\t\t\n\t\t\t\n\t\t
\n\t\t
221.620
\n\t
\n\t
\n\t\t
\n\t\t\t\n\t\t\t\tc11\n\t\t\t\t\n\t\t\t\n\t\t
\n\t\t
3.260·10-3\n\t\t
\n\t
\n
Table 2.
The coefficients of function ηf, (Rtc, ha) given by expression (26) [19].
The differences of air temperature over the first and second tube row can be calculated as follows
Assuming that the heat transfer coefficients in the first and second tube row are equal, i.e. haI = haII = ha and the water side heat transfer coefficient hin is the same in both tubes results in the equality of the numbers of heat transfer units across the first and second row, i.e. Na=NaI=NaII. Hence, the total temperature difference ΔTto over two rows can be defined as
ΔTto=ΔTI+ΔTII=(Tw−T\'a)(1−e−2Na)E29
\n\t\t\t\t
The temperature difference ΔTto given by expression (29) and Eq. (17) are nonlinear functions of the heat transfer coefficient ha. Also, the overall heat transfer coefficient Uo=UoI = UoII is a nonlinear function of h¯a, which in turn depends on ha. The expression (29) is used in Equation (16) to evaluate the heat transfer coefficient ha while the temperature difference ΔT¯to,CFD obtained from the CFD simulations is assumed as a measured temperature difference.
4.2. Determination of the gas-side heat transfer coefficient directly from CFD simulations of fin-and-tube heat exchanger
The method of determining the average heat transfer coefficient directly from CFD simulation was presented in [20]. The average heat transfer coefficients can be calculated, based on the following relationship:
havg,CFD=QAt(T¯wall−T∞),E30
\n\t\t\t\t
where the heat transfer rate, referenced to a single pitch, is:
Q=m˙(i0,outet−i0,inlet),E31
\n\t\t\t\t
where m˙ denotes the mass flow rate of the air, i0, outlet and i0, inlet are the air static enthalpy calculated at the outlet and inlet of the flow passage, respectively. The total heat transfer area is calculated as:
At=Af+Ae,E32
\n\t\t\t\t
the area averaged wall temperature is defined as:
T¯wall=1At∫AtTwalldA,E33
\n\t\t\t\t
the air bulk temperature T∞ is calculated as the arithmetic mean temperature from the air inlet and outlet temperatures:
T∞=T¯a=0.5(Ta\'+Ta\'\'\').E34
\n\t\t\t\t
Correlations for air-side heat transfer coefficient will be determined using both methods presented in this chapter. If the air temperature increase (Ta\'\'\'−Ta\') is small then both procedures described in the sections 4.1 and 4.2 give the same results.
5. Results and discussion
5.1. The correlation on gas-side heat transfer coefficient obtained directly from CFD simulations
Table 3 lists the flow and heat transfer parameters studied during the performed computational cases [20]. Moreover the values of the computed outlet air temperature T’’’a are given in Table 3.
The list of the computational cases used in the CFD simulations and the values of inlet air velocity w0, inlet air temperature T’a, the average heat transfer coefficient for water flow hin, average temperature of water T¯w and outlet temperature of the air T’’’a
The determined values of the average heat transfer coefficients havg.CFD are listed in Table 4 [20]. The computations were carried out for the mean water temperatures: T¯w = 30 ºC and T¯w = 65 ºC, respectively, to demonstrate that the influence of the tube wall temperature on the determined air side heat transfer coefficients is insignificant. The maximum relative difference between the heat transfer coefficients for T¯w = 30 ºC and T¯w = 65 ºC does not exceed 2.9 %. These discrepancies are due to different temperature in the boundary layer, which in turn affects the value of thermal conductivity and kinematic viscosity of air, although the air side Prandtl number is 0.7 in both cases. A similar effect of wall temperature on the value of heat transfer coefficient on the air side can be expected in experimental studies [20].
\n\t
\n\t
\n\t
\n\t
\n\t
\n\t
\n\t\n\t\t
\n\t\t\t
\n\t\t\t\tCase no.\n\t\t\t
\n\t\t\t
\n\t\t\t\t\n\t\t\t\t\tw0, m/s\n\t\t\t\t\n\t\t\t
\n\t\t\t
\n\t\t\t\tQ , W\n\t
\n\t
\n\t\tT¯wall , ºC\n
\n
\n\tT¯a=T∞ , ºC\n
\n
\n\thavg,CFD , W/(m2 K)\n
\n
\n\n
\n\t
1
\n\t
1
\n\t
0.8609
\n\t
59.049
\n\t
37.014
\n\t
39.385
\n
\n
\n\t
2
\n\t
1.2
\n\t
1.0089
\n\t
58.059
\n\t
36.521
\n\t
47.121
\n
\n
\n\t
3
\n\t
1.4
\n\t
1.1445
\n\t
57.152
\n\t
36.066
\n\t
54.155
\n
\n
\n\t
4
\n\t
1.6
\n\t
1.2678
\n\t
56.321
\n\t
35.651
\n\t
60.347
\n
\n
\n\t
5
\n\t
1.8
\n\t
1.3804
\n\t
55.569
\n\t
35.275
\n\t
65.849
\n
\n
\n\t
6
\n\t
2
\n\t
1.4806
\n\t
54.865
\n\t
34.922
\n\t
70.589
\n
\n
\n\t
7
\n\t
2.2
\n\t
1.575
\n\t
54.247
\n\t
34.614
\n\t
74.774
\n
\n
\n\t
8
\n\t
2.4
\n\t
1.6608
\n\t
53.672
\n\t
34.326
\n\t
78.506
\n
\n
\n\t
9
\n\t
2.5
\n\t
1.7007
\n\t
53.403
\n\t
34.191
\n\t
80.204
\n
\n
\n\t
10
\n\t
1
\n\t
0.2570
\n\t
28.228
\n\t
21.604
\n\t
38.913
\n
\n
\n\t
11
\n\t
1.2
\n\t
0.3010
\n\t
27.938
\n\t
21.459
\n\t
46.399
\n
\n
\n\t
12
\n\t
1.4
\n\t
0.3405
\n\t
27.661
\n\t
21.321
\n\t
53.069
\n
\n
\n\t
13
\n\t
1.6
\n\t
0.3765
\n\t
27.416
\n\t
21.198
\n\t
58.935
\n
\n
\n\t
14
\n\t
1.8
\n\t
0.4091
\n\t
27.186
\n\t
21.083
\n\t
64.106
\n
\n
\n\t
15
\n\t
2
\n\t
0.4392
\n\t
26.989
\n\t
20.985
\n\t
68.628
\n
\n
\n\t
16
\n\t
2.2
\n\t
0.4662
\n\t
26.798
\n\t
20.889
\n\t
72.563
\n
\n
\n\t
17
\n\t
2.4
\n\t
0.4913
\n\t
26.625
\n\t
20.803
\n\t
76.083
\n
\n
\n\t
18
\n\t
2.5
\n\t
0.5039
\n\t
26.551
\n\t
20.765
\n\t
77.804
\n
\n
Table 4.
The values of the heat transfer rate Q referenced to a single pitch, the area averaged wall temperature T¯wall, the bulk temperature of the air T∞ and the average heat transfer coefficient havg,CFD for the air flow, obtained for the computational cases listed in Table 1
The values of havg,CFD obtained when T¯w = 30 ºC and T¯w = 65 ºC do not differ significantly for the same air velocity. Table 5 [20] lists the Nusselt number correlation obtained from CFD simulations.
\n\t
\n\t
\n\t
\n\t\n\t\t
\n\t\t\t
No.
\n\t\t\t
Correlation – CFD simulations
\n\t\t\t
Estimated parameters
\n\t\t
\n\t\n\t
\n\t\t
1
\n\t\t
NUa(T∞=65οC)=x1Reax2Pra1/3 150 < Rea < 400 Pra = 0.7
Nusselt number formulas for the air flow Nua obtained from the CFD simulations based on the mean arithmetic temperatures of the air: T∞=65οC and T∞=30οC\n\t\t\t\t\t\t
The air-flow Nusselt number correlations obtained from CFD simulations are compared with the experimental correlations listed in Table 1. Fig. 8 reveals that the correlations for the air-flow Nusselt number, determined via the CFD simulations, predicts slightly lower values than the one obtained via the measurements. The maximum percentage differences can be observed for Rea = 150, where the values of the Nusselt number, obtained using the CFD simulations are from 10.1 % to 13.7% lower than those obtained from the measurements. For the largest value of Rea (Rea = 400) these differences are smaller: from 0.5 % to 8.4 % [20].
Figure 8.
The values of the Nusselt number of the air Nua obtained for the Reynolds numbers Rea = 150 – 400 and the Prandtl number Pra = 0.7, using the correlations listed in Table 1 (experimental correlations: Cor. 1 – Cor. 3) and in Table 5 (correlations based on CFD: Cor. CFD 1, Cor. CFD 2).
Figure 9.
The values of the Nusselt number of water Nuw obtained for the Reynolds numbers Rew = 4000 – 12000 and the Prandtl number Prw = 2.75 using the correlations presented in Table 1.
The values of the Prandtl numbers for the air and water: Pra = 0.7 and Prw = 2.75 are typical for air temperatures T¯a from 10 ºC to 40 ºC and for water temperature T¯w = 65 ºC. Fig. 8 and Fig. 9 reveal that the experimental correlation 1 (see Table 1) predicts the largest values of the Nusselt number for the air flow if Rea > 150 and for water flow if Rew > 10364. Experimental correlation 2 predicts the lowest values of the Nusselt number for the air flow if Rea > 150 and for water flow if Rew > 4000. Experimental correlation 3 predicts slightly larger values of Nua if Rea > 150 and the largest values of Nuw if Rew < 10364.
During the CFD simulations the idealistic heat transfer conditions were assumed: the constant inlet velocity and the perfect contact between the fin and the outer surface of tube wall. In a real fin-and-tube heat exchanger the maldistribution of air flow as well as the thermal contact resistance between the fin and tube [18, 19] can significantly influence the heat and momentum transfer. Furthermore, the maldistributions of water flow to the tubes of heat exchanger exists for these devices [21-23].The circumstances, mentioned above, explain why the Nusselt number correlations obtained using CFD simulation differ slightly from the experimental correlations. The analytical-numerical approach for calculating the average thermal contact resistance for a studied fin-and-tube heat exchanger is presented in section 6.
5.2. The correlation on gas-side heat transfer coefficient obtained using fin-and-tube heat exchanger model and CFD simulations
Application of the proposed method is illustrated by the following data set[19]:
air velocity w0 in front of heat exchanger: 1 m/s – 2.5 m/s,
air temperature before the heat exchanger T’a = 14.98 ºC,
mean water temperature in the tubes Tw = 68.3 ºC,
water side heat transfer coefficient hin = 4793.95 W/(m2·K).
The temperatures T’a, Tw, and the heat transfer coefficient hin were held constant, while the inlet air velocity w0 was varied from w0 = 1 m/s to w0 = 2.5 m/s (Table 6). First, the CFD simulations were performed without including thermal contact resistance (Rtc = 0). Table 6 [19] lists the air temperature differences obtained from the CFD simulations, for the first and second tube rows (ΔT¯I,CFD and ΔT¯II,CFD) as well as the total air temperature difference ΔT¯to,CFD. The secant method was employed to solve the nonlinear algebraic equation (16) for the air-side heat transfer coefficient ha, CFD. The values of ha, CFD and heat transfer coefficients ha, me obtained based on the experimental data (correlation 4 in Table 1), are shown in Table 7 [19].
\n\t
\n\t
\n\t
\n\t
\n\t\n\t\t
\n\t\t\t
\n\t\t\t\t\n\t\t\t\t\tw0 , m/s\n\t\t\t\t\n\t\t\t
\n\t\t\t
\n\t\t\t\tΔT¯I,CFD , ºC\n\t
\n\t
\n\t\tΔT¯II,CFD , ºC\n
\n
\n\tΔT¯to,CFD , ºC\n
\n
\n\n
\n\t
\n\t\t1.0\n\t
\n\t
41.26
\n\t
6.37
\n\t
47.63
\n
\n
\n\t
\n\t\t1.2\n\t
\n\t
39.03
\n\t
7.84
\n\t
46.87
\n
\n
\n\t
\n\t\t1.4\n\t
\n\t
36.80
\n\t
9.00
\n\t
45.80
\n
\n
\n\t
\n\t\t1.6\n\t
\n\t
34.71
\n\t
9.84
\n\t
44.55
\n
\n
\n\t
\n\t\t1.8\n\t
\n\t
32.79
\n\t
10.44
\n\t
43.23
\n
\n
\n\t
\n\t\t2.0\n\t
\n\t
31.04
\n\t
10.82
\n\t
41.86
\n
\n
\n\t
\n\t\t2.2\n\t
\n\t
29.47
\n\t
11.05
\n\t
40.52
\n
\n
\n\t
\n\t\t2.5\n\t
\n\t
27.39
\n\t
11.19
\n\t
38.58
\n
\n
Table 6.
Temperature differences for the first and second row of tubes ΔT¯t,CFD and ΔT¯II,CFD) and the total temperature difference ΔT¯to,CFD obtained using CFD simulations for different air inlet velocities w0
\n\t
\n\t
\n\t
\n\t
\n\t
\n\t
\n\t\n\t\t
\n\t\t\t
\n\t\t\t\t\n\t\t\t\t\tw0 , m/s\n\t\t\t\t\n\t\t\t
\n\t\t\t
\n\t\t\t\tRea\n\t\t\t\t\n\t\t\t
\n\t\t\t
\n\t\t\t\tPra\n\t\t\t\t\n\t\t\t
\n\t\t\t
\n\t\t\t\tjaCFD , -\n\t
\n\t
\n\t\t\n\t\t\tha, CFD , W/(m2·K)\n\t\t\n\t
\n\t
\n\t\t\n\t\t\tha, me , W/(m2·K)\n\t\t\n\t
\n
\n\n
\n\t
\n\t\t1.0\n\t
\n\t
149.87
\n\t
0.694
\n\t
0.026233
\n\t
67.54
\n\t
52.31
\n
\n
\n\t
\n\t\t1.2\n\t
\n\t
180.01
\n\t
0.026226
\n\t
81.02
\n\t
59.19
\n
\n
\n\t
\n\t\t1.4\n\t
\n\t
210.29
\n\t
0.025386
\n\t
91.49
\n\t
65.68
\n
\n
\n\t
\n\t\t1.6\n\t
\n\t
240.70
\n\t
0.024134
\n\t
99.39
\n\t
71.87
\n
\n
\n\t
\n\t\t1.8\n\t
\n\t
271.22
\n\t
0.022781
\n\t
105.53
\n\t
77.81
\n
\n
\n\t
\n\t\t2.0\n\t
\n\t
301.86
\n\t
0.021425
\n\t
110.26
\n\t
83.53
\n
\n
\n\t
\n\t\t2.2\n\t
\n\t
332.60
\n\t
0.020175
\n\t
114.20
\n\t
89.06
\n
\n
\n\t
\n\t\t2.5\n\t
\n\t
378.86
\n\t
0.018529
\n\t
118.94
\n\t
97.04
\n
\n
Table 7.
Air-side heat transfer coefficient for entire heat exchanger obtained from CFD simulation: ha,\n\t\t\t\t\t\t\tCFD and experimental correlation ha,\n\t\t\t\t\t\t\tme (correlation 4 in Table 1) for different air inlet velocities w0.
The air-side Reynolds and Prandtl numbers (Rea and Pra) were calculated as presented in section 3 for the experimental method. For the determined heat transfer coefficients ha,\n\t\t\t\t\tCFD the heat transfer correlations are derived as follows. First, the Colburn factor ja is approximated using the power law function [20]
ja=x1Reax2E35
\n\t\t\t\t
where the Colburn factor ja is defined as [19, 20]
ja=Nua/(ReaPra1/3)E36
\n\t\t\t\t
Based on the heat transfer coefficients ha, CFD obtained from the solution of Equation (16), the Colburn factors (Table 7)\n\t\t\t\t\tja,iCFD=Nua,iCFD/(Rea,iPra,i1/3),\n\t\t\t\t\ti = 1,.., 8, were calculated. The symbol Nua,iCFD=ha,CFDdhka is the Nusselt number for ith data set CFD. The unknown coefficients x1 and x2 in the function (35) were determined using the least squares method. The coefficients x1 and x2 were selected to minimize the following sum of squares:
S=∑i=1n=8(ja,iCFD−x1Rea,ix2)2E37
\n\t\t\t\t
The symbol n is the number of data sets shown in Table 7.
The coefficients x1 and x2 obtained using the least squares method for the data sets listed in Table 5 are: x1 = 0.188 and x2 = - 0.382. To find the optimum values of x1 and x2 the Levenberg-Marquardt method was used [35]. The MATLAB R2012 curve fitting toolbox [42] was used for this purpose. Figure 10 [19] depicts the obtained correlation jaCFD(Rea), also the prediction bounds set at 95 % confidence level are presented.
Figure 10.
Correlation jaCFD(Rea)=0.188Rea−0.382 - continuous line, and prediction bounds set at 95% confidence level – dashed line. The correlation was based on the CFD data set.
Fig. 10 reveals that the correlation ja(Rea)=0.1878Rea−0.382 predicts the values of Colburn factor jaCFD well for Rea\n\t\t\t\t\t∈ (170, 390). The expression on the air side Nusselt number is obtained after rearranging Eq. (36)
Nua=x1Rea(1+x2)Pr1/3E38
\n\t\t\t\t
The following formula for the air-side heat transfer coefficient was obtained after substituting the estimated coefficients x1 and x2 into the correlation (38),
ha,CFD=kadhNua=kadh0.188Rea0.618Pra1/3E39
\n\t\t\t\t
In ref. [37] similar correlations for continuous-fin and tube heat exchangers can be found. The correlation
ha=kadh0.174Rea0.613Pra1/3E40
\n\t\t\t\t
obtained by Kröger [38] is similar to the correlation (39).
The thermal contact resistance exists between the tube and fin for some methods of attaching the fins on the tubes. It reduces the heat transfer rate between the fluids in the heat exchanger.
The correlation (39) leads to over-prediction of the heat transfer rate from the hot to the cold fluid, when the contact resistance occurs. The thermal contact resistance between the tube and the fin base will be determined by using the correlation (39) and the experimental results.
6. Estimation of the thermal contact resistance between the tube outer surface and fin base usingCFD simulations and experimental data
The correlation for the air-side Nusselt number was derived based on: the experimental data and the CFD simulation. The values of the heat transfer coefficients obtained from the CFD simulation ha, CFD and from the experiment ha, me differ from each other (compare Table1 and Table 7). The method based on the CFD simulation gives larger values of ha in comparison to the experimental-numerical method (Table 7). The reason for this discrepancy is the thermal contact resistance between the fin and tube in the tested car radiator.
The air temperature increase across two tube rows ΔT¯to,CFD calculated using the heat transfer coefficient ha, CFD obtained from the CFD based method, is greater than the calculated temperature rise ΔT¯to,me obtained with the heat transfer coefficient ha, me. The temperature differences ΔT¯to,CFD and ΔT¯to,me can be equal if a thermal contact resistance is included in the CFD simulations.
The air temperature difference ΔT¯to,CFD through the entire heat exchanger depends on the thermal contact resistance Rtc and air-side heat transfer coefficient ha. To determine the thermal contact resistance Rtc, the nonlinear algebraic equation
ΔT¯to,CFD(Rtc,ha,CFD)−ΔT¯to,me=0E41
\n\t\t\t
was solved, for the given values of ha, CFD, listed in Table 7. The value of the thermal contact resistance Rtc was so adjusted that Eq. (41) is satisfied. Equation (41) was solved using the Secant method. Note that the predicted value of total air temperature difference ΔTto, CFD determined from Eq. (29) depends on fin-efficiency ηf, which in turns depends on Rtc. Heat transfer coefficient ha, CFD is a function of air velocity w0 and is independent of the thermal contact resistance Rtc. The heat transfer coefficient ha, CFD was calculated using the correlation (39).
Table 8 [19] lists the measurement data sets and the obtained values of thermal contact resistance.
\n\t
\n\t
\n\t
\n\t
\n\t
\n\t
\n\t
\n\t
\n\t
\n\t\n\t\t
\n\t\t\t
\n\t\t\t\tCase\n\t\t\t
\n\t\t\t
\n\t\t\t\t\n\t\t\t\t\tw0 , m/s\n\t\t\t\t\n\t\t\t
\n\t\t\t
\n\t\t\t\t\n\t\t\t\t\tT’a, ºC\n\t\t\t\t\n\t\t\t
\n\t\t\t
\n\t\t\t\tΔT¯to,me , ºC\n\t
\n\t
\n\t\t\n\t\t\tTw, ºC\n\t\t\n\t
\n\t
\n\t\tV˙w , dm3/h\n
\n
\n\t\n\t\thin , \n\t\t\n\t\n\t \n\tW/(m2·K)\n
\n
\n\t\n\t\tha, CFD , \n\t\n\t \n\tW/(m2·K)\n
\n
\n\t\n\t\tRtc , \n\t\n\t \n\t(m2·K)/W\n
\n
\n\n
\n\t
\n\t\tI\n\t
\n\t
1.00
\n\t
14.98
\n\t
42.67
\n\t
68.35
\n\t
1, 892.40
\n\t
4, 793.95
\n\t
71.14
\n\t
4.45·10-5\n\t
\n
\n
\n\t
\n\t\tII\n\t
\n\t
1.27
\n\t
13.49
\n\t
39.74
\n\t
65.02
\n\t
1, 882.20
\n\t
4, 813.42
\n\t
82.45
\n\t
3.27·10-5\n\t
\n
\n
\n\t
\n\t\tIII\n\t
\n\t
1.77
\n\t
13.03
\n\t
35.83
\n\t
63.14
\n\t
1, 789.80
\n\t
4, 743.65
\n\t
101.03
\n\t
2.42·10-5\n\t
\n
\n
\n\t
\n\t\tIV\n\t
\n\t
2.20
\n\t
12.69
\n\t
31.83
\n\t
61.24
\n\t
1, 788.00
\n\t
4, 739.78
\n\t
115.34
\n\t
2.42·10-5\n\t
\n
\n
\n\t
\n\t
\n\t
\n\t
\n\t
\n\t
\n\t
\n\t
R¯tc
\n
3.16·10-5\n
\n
\n
Table 8.
Thermal contact resistance Rtc determined using experimental data sets and the heat transfer coefficient ha, CFD obtained from the CFD simulations
The mean value of thermal contact resistance, obtained for data set given in Table 8, is R¯tc = 3.16 10-5 (m2K)/W. To calculate the total air temperature differences ΔT¯to,CFD the R¯tc was included in the CFD model of heat exchanger.
Figure 11 presents the results of CFD simulations for computational cases listed in Table 8.
Figure 11.
The results of CFD simulation for data sets I - IV listed in Table 8: a) temperature distribution in the air domain at the middle of flow passage, b) fin surface temperature, c) air velocity distribution at the middle of flow passage [19].
Equation (14) was used to determine the heat flux q variations at the outer surface of tube wall with dimensionless coordinate ξ. Fig. 12 presents the results for the first tube row and Fig 13 for the second tube row [19]. Additionally, the computed values of heat flux q for the thermal contact resistance R¯tc = 0 (m2 K)/W are compared with that obtained for R¯tc = 3.16 10-5 (m2 K)/W.
Figure 12.
The distribution of heat flux q on the outer surface of tube wall for the first tube row, for computational cases I - IV listed in Table 8.
Figure 13.
The distribution of heat flux q on the outer surface of tube wall for the second tube row, for computational cases I - IV listed in Table 8.
Fig 12 reveals that the thermal contact resistance significantly reduces heat flux through the finned outer surface of the tube. The influence of contact resistance on the average heat flux in the second row of tubes (Fig. 13) is smaller than in the first row of tubes (Fig. 12). The overall heat transfer rate decreases significantly if the thermal contact resistance exists because the largest amount of heat is transferred across the first row of tubes.
Table 9 [19] compares the temperature differences across the two rows of tubes computed using ANSYS CFX for the average thermal contact resistance R¯tc = 3.16 10-5 (m2 K)/W with the temperature differences obtained from the expression (29) for the experimentally determined heat transfer coefficient ha, me (correlation 4, Table 1)
Air temperature differences ΔT¯to,CFD over two rows of tubes obtained using the CFD simulations with the thermal contact resistance R¯tc = 3.16 10-5 (m2 K)/W and the temperature difference ΔT¯to,me obtained from Eq. (29) for the experimentally detemined heat transfer coefficients ha, me
The relative temperature difference |εa| between the obtained results, is calculated as:
|εa|=|ΔT¯t−ΔT¯t,meΔT¯t,me|⋅100%.E42
\n\t\t\t
The largest value of this difference was obtainedfor the case I - |εa| = 3.98 % (Table 9). For the other computational test cases, the value of |εa| is less than 3 %. The performed calculations demonstrate the effectiveness of the method developed. The estimated contact resistance can be used in the calculation of equivalent heat transfer coefficient using (Eq. (25)) and in the analytical calculations of the heat transfer rate in the heat exchanger:
Q˙=FAoUoΔTlmE43
\n\t\t\t
where the symbol F denotes the correction factor based on the logarithmic mean temperature difference ∆Tlm for a counter-current flow arrangement.
The method proposed for determining the air side heat transfer correlations based on the CFD computations, can easily account for the thermal contact resistance between the tube outer surface and fin bases. The method can also be used for heat exchangers with various tube shapes and other types of the fin to tube attachment as well as for different tube arrangements.
7. Conclusions
The experimental and CFD based methods for determining the air-side heat transfer coefficient, for fin-and-tube heat exchanger, are presented in this study. Two types of CFD based methods were described. The first one allows determining the air-side heat transfer coefficient directly from CFD simulations while the second employs the analytical model of fin-and-tube heat exchanger to determine the air-side heat transfer coefficient. The results obtained using these two methods were compared with the experimental data.
Moreover, the method for determination of the thermal contact resistance between the fin and tube was presented. The CFD simulations are appropriate for predicting heat transfer correlations for the plate fin and tube heat exchanger with tubes of various shapes and flow arrangements. Using the experimental data and CFD simulations, the thermal contact resistance between the fin base and tube was estimated. The fin efficiency appearing in the formula for the equivalent air side heat transfer coefficient is a function of the air side heat transfer coefficient and the thermal contact resistance. The air-side heat transfer correlations are determined based on the CFD simulations. The heat transfer coefficients predicted from the CFD simulations were larger than those obtained experimentally, because in the CFD modeling the thermal contact resistance between the fin and tube was neglected. A new procedure for estimating the thermal contact resistance was developed to improve the accuracy of the heat exchanger calculation. When the value of mean thermal contact resistance, determined by the proposed method, is included in the CFD model, then the computed air temperature distributions show better agreement with measurements.
The computations presented in this study allows to draw the following conclusions. CFD modeling is an effective tool for flow and thermal design of plate fin-and-tube heat exchangers. and is an effective tool for finding heat transfer correlations in the newly designed heat exchangers. However, to obtain good agreement between the CFD modeling and experimental data, it is necessary to adjust some parameters of the CFD model using the experimental results. An example of such a parameter may be thermal contact resistance between the tube and the fin base.
Nomenclature
A; area, m2
Aoval; area of oval cross-section, m2
cp; specific heat at constant pressure, J/(kg K)
c1 - c11; coefficients of function ηf (Rtc, ha)
dh; hydraulic diameter of narrow air flow passage, m
dmin, dmax; minor/major oval axes, m
dt; hydraulic diameter of oval tube, m
F; correction factor
h; heat transfer coefficient, W/(m2K)
h¯ ; enhanced heat transfer coefficient based on tube outer surface Ao, W/(m2K)
j; Colburn j-factor, Nu/(Re Pr1/3)
k; thermal conductivity, W/(mK)
Lt; tube length in car radiator, m
m˙ ; mass flow rate, kg/s
N; number of transfer units
Nu; Nusselt number
p1; pitch of tubes in plane perpendicular to flow, m
p2; pitch of tubes in direction of flow, m
P; perimeter, m
Pr; Prandtl number
Rtc; mean thermal contact resistance between tube and fin, m2K/W
Re; Reynolds number
q; heat flux, W/m2
q¯I,q¯II average heat flux on the outer surface of tube in the first and second tube row, W/m2Q˙ ; heat flow, W
s; thickness of air flow passage, m
T; temperature, °C
T¯a,T¯w mean temperature of air/water in heat exchanger, °C
U; overall heat transfer coefficient, W/(m2K)
V˙ ; volumetric flow rate, dm3/h
w; velocity, m/s;
w0; air inlet velocity, m/s;
wmax; maximum air velocity in narrow flow passage, m/s;
x, y, z; Cartesian coordinates, m
y¯ distance, measured along the flow direction, between the oval gravity center and the point located at the outer surface of tube wall, m
xi; unknown coefficient
Greek symbols
δ; thickness, m
∆T; air side temperature difference obtained using analytical model of heat exchanger, °C
ΔT¯ ; air side temperature difference obtained from the CFD simulations, °C
|εa|; relative change of the air temperature increase, %
ηf; fin efficiency
μ; dynamic viscosity, Ns/m2
ν; kinematic viscosity, m2/s
ξ; Darcy Weisbach friction factor
Subscripts
a; air
c; contact area
CFD; obtained using CFD based method
e; external surface of tube between fins
f; fin
g; external surface of tube without fins
in; inner
m; logarithmic mean temperature difference
me; measured temperature difference on air side
min minimum cross-section area for transversal air flow through the tube array
o; outer
t; tube
to; total air side temperature difference
w; water
I, II; first and second tube row, respectively
Superscripts
’; inlet
’’; intermediate
’’’; outlet
\n',keywords:null,chapterPDFUrl:"https://cdn.intechopen.com/pdfs/48570.pdf",chapterXML:"https://mts.intechopen.com/source/xml/48570.xml",downloadPdfUrl:"/chapter/pdf-download/48570",previewPdfUrl:"/chapter/pdf-preview/48570",totalDownloads:2240,totalViews:512,totalCrossrefCites:1,totalDimensionsCites:3,totalAltmetricsMentions:0,introChapter:null,impactScore:1,impactScorePercentile:55,impactScoreQuartile:3,hasAltmetrics:0,dateSubmitted:"June 20th 2014",dateReviewed:"April 16th 2015",datePrePublished:null,datePublished:"July 29th 2015",dateFinished:"June 17th 2015",readingETA:"0",abstract:null,reviewType:"peer-reviewed",bibtexUrl:"/chapter/bibtex/48570",risUrl:"/chapter/ris/48570",book:{id:"4563",slug:"heat-transfer-studies-and-applications"},signatures:"Jan Taler, Paweł Ocłoń, Dawid Taler and Marzena Nowak-Ocłoń",authors:[{id:"43955",title:"Prof.",name:"Jan",middleName:"Marian",surname:"Taler",fullName:"Jan Taler",slug:"jan-taler",email:"taler@mech.pk.edu.pl",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/43955/images/1248_n.jpg",institution:{name:"Cracow University of Technology",institutionURL:null,country:{name:"Poland"}}},{id:"172658",title:"Dr.",name:"Paweł",middleName:null,surname:"Ocłoń",fullName:"Paweł Ocłoń",slug:"pawel-oclon",email:"poclon@mech.pk.edu.pl",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"172660",title:"Prof.",name:"Dawid",middleName:null,surname:"Taler",fullName:"Dawid Taler",slug:"dawid-taler",email:"dtaler@mech.pk.edu.pl",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"172661",title:"MSc.",name:"Marzena",middleName:null,surname:"Nowak",fullName:"Marzena Nowak",slug:"marzena-nowak",email:"mnowak@mech.pk.edu.pl",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null}],sections:[{id:"sec_1",title:"1. Introduction",level:"1"},{id:"sec_2",title:"2. Test facility – fin-and-tube heat exchanger with oval tubes",level:"1"},{id:"sec_3",title:"3. Experimental methods of determining the air-side heat transfer coefficient in fin-and-tube heat exchanger",level:"1"},{id:"sec_4",title:"4. Determining of the air-side heat transfer coefficient using CFD simulations",level:"1"},{id:"sec_4_2",title:"4.1. Determination of the gas-side heat transfer coefficient using the analytical model of fin-and-tube heat exchanger and CFD simulation results",level:"2"},{id:"sec_5_2",title:"4.2. Determination of the gas-side heat transfer coefficient directly from CFD simulations of fin-and-tube heat exchanger",level:"2"},{id:"sec_7",title:"5. Results and discussion",level:"1"},{id:"sec_7_2",title:"5.1. The correlation on gas-side heat transfer coefficient obtained directly from CFD simulations",level:"2"},{id:"sec_8_2",title:"5.2. The correlation on gas-side heat transfer coefficient obtained using fin-and-tube heat exchanger model and CFD simulations",level:"2"},{id:"sec_10",title:"6. Estimation of the thermal contact resistance between the tube outer surface and fin base usingCFD simulations and experimental data",level:"1"},{id:"sec_11",title:"7. Conclusions",level:"1"},{id:"sec_12",title:"Nomenclature",level:"1"},{id:"sec_13",title:"Greek symbols",level:"1"},{id:"sec_14",title:"Subscripts",level:"1"},{id:"sec_15",title:"Superscripts",level:"1"}],chapterReferences:[{id:"B1",body:'Matos R. S., Vargas J. V. C., Laursen T. A., Bejan A., 2004: Optimally staggered finned circular and elliptic tubes in forced convection, International Journal of Heat and Mass Transfer 47(6-7): 1347–1359.'},{id:"B2",body:'Jang J. Y., Yang J. Y., 1998: Experimental and Numerical Analysis of the Thermal-Hydraulic Characteristics of Elliptic Finned-Tube Heat Exchangers, Heat Transfer Engineering 19(4): 55-67.'},{id:"B3",body:'Li. 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L., 1996: Calculation of Fin Efficiency for Wet and Dry Fins, HVAC&R Research 2(1): 27 -41.'},{id:"B11",body:'Taler D., 2002: Theoretical and experimental analysis of heat exchangers with extended surfaces, Polish Academy of Science publishing press, ISBN 83-915470-1-9, Poland.'},{id:"B12",body:'Zilio C., Cecchinato L., Corradi M., Schiochet G., 2007: An Assessment of Heat Transfer through Fins in a Fin-and-Tube Gas Cooler for Transcritical Carbon Dioxide Cycles, HVAC&R Research 13(3): 457-469.'},{id:"B13",body:'Taler D., 2004: Determination of heat transfer correlations for plate-fin-and-tube heat exchangers, Heat and Mass Transfer, Vol. 40: 809-822.'},{id:"B14",body:'Taler D., 2007a: Experimental and numerical predictions of the heat transfer correlations in the cross-flow plate fin and tube heat exchangers, Archives of Thermodynamics 28(2): 3-18.'},{id:"B15",body:'Taler D., 2007b: Effect of thermal contact resistance on the heat transfer in plate finned tube heat exchangers, ECI Symposium Series, Volume RP5: Proceedings of 7th International Conference on Heat Exchanger Fouling and Cleaning – Challenges and Opportunities, pp. 362-371, H Müller-Steinhagen, M. R. Malayeri, P. Watkinson (Eds.), Engineering Conferences International, Tomar, Portugal.'},{id:"B16",body:'Taler D., 2009: Dynamics of Tube Heat Exchangers (in Polish), Monograph 193, AGH University of Science and Technology Press, ISSN 0867-6631, Cracow, Poland.'},{id:"B17",body:'Taler D., 2013: Experimental determination of correlations for average heat transfer coefficients in heat exchangers on both fluid sides, Heat and Mass Transfer, Vol. 49. 1125-1139.'},{id:"B18",body:'Taler, D., Cebula, A., 2010: A new method for determination of thermal contact resistance of a fin-to-tube attachment in plate fin-and-tube heat exchangers, Chemical and Process Engineering 31(4): 839-855.'},{id:"B19",body:'Taler D., Ocłoń P., Thermal contact resistance in plate fin-and-tube heat exchangers, determined by experimental data and CFD simulations, International Journal of Thermal Sciences, Volume 84, October 2014, Pages 309-322.'},{id:"B20",body:'Taler D., Ocłoń P., Determination of heat transfer formulas for gas flow in fin-and-tube heat exchanger with oval tubes using CFD simulations, Chemical Engineering and Processing: Process Intensification, Volume 83, September 2014, Pages 1-11.'},{id:"B21",body:'Łopata S, Ocłoń P (2010) Investigation of the flow conditions in a high-performance heat exchanger, Arch Thermodyn 31(3):37–53.'},{id:"B22",body:'Łopata S, Ocłoń P (2012) Analysis of operating conditions for high performance heat exchanger with the finned elliptical tube, Rynek Energii 5(102):112–124.'},{id:"B23",body:'Łopata S, Ocłoń P (2012) Modelling and optimizing operating conditions of heat exchanger with finned elliptical tubes. In: Hector Juarez L (ed) Fluid dynamics, computational modeling and applications, InTech, pp 327–356. ISBN:978-953-51-0052-2, Rijeka.'},{id:"B24",body:'Ocłoń P, Łopata S, Nowak M (2013) Comparative study of conjugate gradient algorithms performance on the example of steady-state axisymmetric heat transfer problem. Arch Thermodyn 34(3):15–44.'},{id:"B25",body:'Ocłoń P, Łopata S, Nowak M, Benim AC (2014) Numerical study on the effect of inner tube fouling on the thermal performance of high-temperature fin-and-tube heat exchanger. Prog Comput Fluid Dyn (accepted for print)'},{id:"B26",body:'Taler J., Taler D., Sobota T., Cebula A., 2012: Theoretical and Experimental Study of Flow and Heat Transfer in a Tube Bank, in V. M. Pertowa (Ed), Advances in Engineering Research, Vol. 1, Nova Science Publishers Inc., pp. 1-56, New York.'},{id:"B27",body:'He Y., Tao Y., Tao W., 2008, : Numerical study on the performance of wavy fin heat exchangers with different elliptic tube patterns, Progress in Computational Fluid Dynamics, An Int. J. 8 (7/8): 510 – 517.'},{id:"B28",body:'Wu Z., Ding G., Wang K.., Fukaya M., 2008a: An Extension of a Steady-State Model for Fin-and-Tube Heat Exchangers to Include Those Using Capillary Tubes for Flow Control, HVAC&R Research, 14(1): 85-101.'},{id:"B29",body:'Liu L., Fan Y., Ling X., Peng H., 2013: Flow and heat transfer characteristics of finned tube with internal and external fins in air cooler for waste heat recovery of gas-fired boiler system, Chemical Engineering and Processing: Process Intensification, 74: 142-152.'},{id:"B30",body:'Li. B., Feng B., He Y. L., Tao W.Q., 2006: Experimental study on friction factor and numerical simulation on flow and heat transfer in an alternating elliptical axis tube, Applied Thermal Engineering, 26(17–18): 2336–2344.'},{id:"B31",body:'ANSYS CFX, 2009: Solver Theory Guide r12, ANSYS Inc.'},{id:"B32",body:'Chung T. J., 2010: Computational Fluid Dynamics 2nd ed., ISBN 978-0521769693, Cambridge University Press, USA.'},{id:"B33",body:'Menter, F. R., 1993: Zonal Two Equation k-ω Turbulence Models for Aerodynamic Flows, AIAA Paper 93-2906.'},{id:"B34",body:'Langtry R. B., Menter F. R., 2005: Transition Modeling for General CFD Applications in Aeronautics, AIAA paper.'},{id:"B35",body:'Seber G. A. F., Wild C. J., 1989: Nonlinear Regression, ISBN 978-0471617600, John Wiley & Sons, New York.'},{id:"B36",body:'Table Curve, 2005: Automated Curve Fitting Software, AISN Software, Chicago.'},{id:"B37",body:'T. Kuppan, Heat exchanger design handbook, 2nd ed., CRC Press – Taylor and Francis Group, 2013, Boca Raton.'},{id:"B38",body:'D. G. Kröger, Radiator characterization and optimization, SAE Paper 840380, 1985, pp. 2.984 – 2.990.'},{id:"B39",body:'Gnielinski, V., 1976: Neue Gleichungen für den Wärme- und den Stoffübergang in turbulent durchströmten Rohren und Kanälen, Forschung im Ingenieurwesen 41(1): 8-16.'},{id:"B40",body:'Pietukhov B. S., Popov V. N., 1963: Theoretical Calculations of Heat Transfer in Turbulent Flow in Tubes of an Incompressible Fluid with Variable Physical Properties, High Temperature Institute Paper, 1(1), pp. 69-83 (in Russian).'},{id:"B41",body:'Bejan A., 2003: Forced Convection: Internal Flows, Chapter 5 in Heat Transfer Handbook, Bejan A. Kraus S. (Eds.), ISBN 978-0-471-39015-2, Wiley, Hoboken.'},{id:"B42",body:'MATLAB, 2013: MATLAB online documentation: http://www.mathworks.com/help/matlab, MathWorks'}],footnotes:[],contributors:[{corresp:"yes",contributorFullName:"Jan Taler",address:"taler@mech.pk.edu.pl",affiliation:'
Cracow University of Technology, Faculty of Mechanical Engineering, Institute of Thermal Power Engineering, Cracow, Poland
Cracow University of Technology, Faculty of Mechanical Engineering, Institute of Thermal Power Engineering, Cracow, Poland
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1. Introduction
Mushrooms are a group of fungi with a distinctive fruiting body that can be either epigeous or hypogenous and large enough to be seen with the naked eye and picked by hand [1]. They are either saprophytic, parasitic or mycorrhizal. Out of these three categories, the majority of them are saprophytic and they play an important role in the biodegradation and bioremediation of recalcitrant substances [2]. Notably, there are about 14,000 mushroom species that have been reported to date and a further 126,000 species more are yet to be discovered [3]. The majority of mushroom species are edible and over 400 species are poisonous [4]. Out of these more than 2000 edible species, 5–6 species are grown on a mass scale, 40 species are produced commercially and 80 species are cultivated experimentally (Figure 1). Edible mushrooms have very minimal calorie value as they contain less amounts fat and carbohydrate and are also cholesterol-free. In addition, edible mushrooms are rich in other vital nutrients like niacin, vitamin D, proteins, selenium, potassium, riboflavin. Mushrooms also contain a significant amount of fiber which helps in the appropriate digestion of food (Table 1) [1]. The active compounds in common mushrooms and the nutritional value of these mushrooms and their activities were showed in Table 2 and Figure 2.
Oxidative stress (OS) is one of the major causes of any disease such as neurodegenerative (NDs), cardiovascular (CDs) and reproductive diseases (RDs), and diabetes [17]. Inflammation is the progressive result of the severe burden of OS. Any biomolecules with anti-oxidative and anti-inflammatory activity show a better response in the treatment of the above diseases [18]. The polyphenols, terpenoids, alkaloids, and other important biomolecules found in edible mushrooms prove their efficacy in therapeutics with minimal side effects [19]. Mushrooms and their biomolecules are known to have been used to cure diabetes by Indian and Chinese patents from ancient times [20]. The active components in these mushroom species; Ganoderma lucidum, Lentinus edodes, Pleurotus ostreatus, Pleurotus sajor-caju, Grifola frondosa, Poriacocos, have exhibited potent anti-diabetic activity [21]. For example, the polysaccharides derived from Pleurotus ostreatus exhibits potent antidiabetic activity in the streptozotocin-persuaded Diabetic Rat model [22]. β-glucans and several other biomolecules present in edible mushrooms show strong anti-diabetic activity [23]. Recently the edible oyster mushroom Pleurotus fossulatus aqueous extract improved liver and kidney function in the streptozotocin-induced diabetic rats, besides reducing blood glucose levels, total cholesterol (TC), triglyceride (TG), and high-density lipoprotein (HDL) [24].
Disorders related to the heart and blood vessels are grouped into cardiovascular diseases (CVDs) [25]. Mushrooms and their bioactive components can prevent CVDs [26]. Being functional foods, edible mushrooms contain a significant number of bioactive compounds that show strong potential in the treatment of CVDs [27]. The antioxidant and anti- inflammatory biomolecules present in mushrooms reduce the atherosclerosis risk which is directly related to CVDs [28]. Diseases related to the reproductive systems are very common now a day. Abnormalities in the endocrine system are mainly responsible for the progression of reproductive diseases (RDs). Several RDs like reproductive tract infections, prostate cancer, breast cancer, ovarian cancer, etc. are most common in different populations [29]. Mushrooms and their bioactive molecules show anti-tumor activity which can be immensely beneficial in the treatment of different RDs. RDs commonly lead to different types of cancer and several biomolecules present in edible mushrooms can prevent metastasis toward cancer [1, 26]. Neurodegenerative diseases (NDs) like Huntington’s disease (HD), Alzheimer’s disease (AD), and Parkinson’s disease (PD), etc. have been effectively treated by edible mushrooms through their bioactive components [30]. Progression of the NDs is the main cause of death which can be significantly inhibited by the biomolecules present in edible mushrooms [31]. Polyphenols, alkaloids, and several other biomolecules in edible mushrooms prove their efficacy in the treatment of different neurodegenerative diseases [32]. Similarly, a different form of cancer can also be treated by the biomolecules found in edible mushrooms [23]. This review discusses the role of mushrooms and their biomolecules to be utilized for the treatment of some most common diseases like CVDs, RDs, NDs, diabetes, and the different forms of cancer.
2. Mushroom active compounds against cardiovascular diseases (CVDs)
Cardio Vascular Diseases (CVDs) are a category of heart and blood diseases, including coronary heart disease, cerebrovascular disease, rheumatic heart disease, and other diseases. CVDs are the leading cause of death worldwide. In the past few decades, researchers have shown the use of mushrooms and their bioactive compounds as therapeutic agents for CVDs. In 2010, Guillamon et al. reported the potentially positive effects of mushroom consumption on risk markers for CVDs and identified some potential bioactive compounds responsible for their therapeutic activity. Several studies have shown the influence of mushroom intake on some metabolic markers (total low-density lipoproteins (LDL), high-density lipoproteins (HDL): cholesterol, fasting triacylglycerol, homocysteine, blood pressure) which could potentially reduce the risk of cardiovascular disease. Relevant nutritional aspects of mushrooms include high fiber content, low-fat content, and low trans isomers of unsaturated fatty acids. Mushrooms also have low sodium concentrations and other significant components, such as eritadenine, phenolic compounds, sterols (such as ergosterol), chitosan, triterpenes, etc., which are considered to be potential agents for some previously healthy properties. The intake of mushrooms has a cholesterol-lowering or hypocholesterolemic effect which has been elucidated by different mechanisms, such as lowering of very-low-density lipoproteins (VLDL), improving lipid metabolism, inhibiting the activity of HMG-CoA reductase and therefore, prevents the development of atherosclerosis (Figure 3). Antioxidants and anti-inflammatory compounds found in mushrooms also reduce the risk of atherosclerosis [26]. Ganoderma lucidum play a curicral role in mitigating the toxicity of Adriamycin, where, Adriamycin treatment raised the number of marker enzymes found in serum including aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatine kinase (CK), and lactate dehydrogenase (LDH). In order to increase lipid peroxidation (LPO), adriamycin significantly decreased antioxidant enzymes in the cardiac tissues, including glutathione-S-transferase (GST), glutathione peroxidase (GPx), catalase (CAT), and superoxide dismutase (SOD). Adriamycin has also been shown to considerably lower glutathione (GSH) levels. This study has shown that G. Lucidum extracts have significant antioxidant properties and protect the heart from the free radical-mediated toxicity of adriamycin. G. Lucidum extract retrieves free radicals and also increases the levels of glutathione and antioxidant enzymes [33]. Important findings show that the edible mushrooms could be used as possible sources of novel hypocholesterolemia agents. Few studies have identified the levels of sterols, b-glucans, and HMGCoA-red as inhibitors in mushrooms. Ergosterol was the most plentiful sterol recorded in all the samples examined, apart from G. lucidum, which had identical levels of ergosterol and ergosta-7,22-dienol. P. ostreatus, G. lucidum, A. aegerita, and L. edodes mushrooms had high levels of b-glucan content, whereas A. Blazeii, A. Bisporus, and L. procera had low levels of β-glucan content. Because of the presence of lovastatin, a statin found in mycelia broths and its fruiting bodies, the oyster mushroom (Pleurotus spp.) reduces blood cholesterol levels. As a result, a mixture of bioactive supplements improves the nutritional ability of different mushrooms to lower serum cholesterol levels [31]. A study has assessed the effect of different mushroom-like Lentinus edodes, Auricularia polytricha, and Flammulina velutipes preparations on the levels of cholesterol in the rats which showed that the preparation of dried mushrooms significantly reduced plasma cholesterol levels. Lentinus edodes was more effective, while Auricularia polytricha (Jews-ear) and Flammulina velutipes were less effective than L. edodes, Kohshin. However, ergosterol supplements have caused a marked decrease in hepatic cholesterol levels [34]. A previous study, focusing on the hypolipidemic effects of polysaccharides, isolated from Pholiota Nameko (PNPS-1) was conducted on hyperlipidemic Wistar rats. The rats were treated with PNPS-1 at different doses which reduced very-low-density: lipoprotein/low-density lipoprotein cholesterol, triacylglycerol, phospholipids, and increased the atherogenic index and high-density lipoprotein cholesterol in the serum. PNPS-1 also improved pathological changes in the coronary arteries of hyperlipidemic rats. These results suggest that PNPS-1 significantly reduces the development of hyperlipidemia and could be used as a potential therapeutic agent for CVD [35]. Anti-atherogenic and antiatherosclerotic effects of different mushrooms belonging to the genera: Armillaria, Agaricus, Boletus, Collybia, Cortinfrius, Coriolus, Flammulina, Hirneola, Lentinus, Ganoderrna, Lyophyllurn, Sarcodon, Pleurotus, Tricholoma, and Trenella were detected in human intima aortic culture. The results showed that anti-atherosclerotic, anti-atherogenic, and hypolipidemic effects of certain species of mushrooms allow us to speculate that these edible fungi are beneficial dietary supplements that might be utilized in prophylactics and to a limited extent, in atherosclerotic medicines. Furthermore, the extraction and purification of the active substance from these mushrooms may result in the development of a strong anti-atherosclerotic medicine [36]. Among the Pleurotus species, P. ostreatus was the best candidate for the prevention and treatment of atherosclerosis because it has been shown to contain a large number of antiatherosclerotic agents such as ergothionein, lovastatin, and chrysin [37].
Figure 3.
Mushroom active compounds against cardiovascular diseases (CVDs).
3. Antidiabetic activity of mushroom biomolecules
Mushrooms are fungi that either grow above or below the ground. These are the macro fungi that can be easily seen with the naked eye. Mushrooms have been used since ancient times by the people of India and China or their medicinal properties. Nowadays many countries are consuming mushrooms for not only their unique flavor but also for their culinary effects. As many studies have revealed that mushrooms are rich sources of: proteins, carbohydrates, vitamins (B1, B2, B12, C, D, and E) and minerals like Mn, Mg, Se, Ca, Na, Cu, K, and Fe [38]. These nutritional factors in mushrooms have made it very efficient to fight diabetes. In vitro and in vivo studies have shown that the extract of mushrooms can reduce the expression of proinflammatory cytokines, induced by lipopolysaccharides which further improved the glucose uptake in skeletal muscle cell lines [39].
One of the most active biomolecules of mushrooms is β-glucans, a polysaccharide that can protect the pancreatic tissue from damage and restore the function of b-cells which helps to lower the blood glucose levels [40]. The low energy, lack of cholesterol and fats, less carbohydrates, and high minerals, proteins and vitamins made mushrooms an ideal food for diabetic patients. The consumption of mushrooms for a few days only can help to manage the low-density lipoproteins, total cholesterol, high-density lipoprotein, triglycerides levels in serum [10]. Besides bioactive molecules, mushrooms are very good in antioxidants activity and are also a good source of dietary fibers and water. Some of the most culinary properties containing mushrooms are Agaricus bisporus, Agaricus subrufescens, Cordyceps millitaris, Cordyceps sinensis, Grifola frondosa, Ganoderma lucidum, Phellinus linteus, Pleurotus flabellatus, Pleurotus citrinopileatus, Pleurotus ostreatus, Poria cocos [10, 41]. Extracts of Ganoderma lucidum contain: polysaccharides, triterpenoids, proteoglycans, and proteins which have been shown to reduce blood glucose levels. The proteoglycans of G. lucidum inhibit the tyrosine phosphatase 1B protein in diabetic patients. G. lucidum has proven to be very effective in controlling diabetes. Moreover, the triterpenoid from G. lucidum inhibits the aldose reductase and a-glucosidase enzymes which are responsible for the elevation of postprandial glucose levels [42]. Polysaccharides from G. atrum (PSG-1) increase insulin sensitivity and lower the serum lipid by increasing and decreasing the expression levels of Bcl-2 and Bax, respectively in pancreatic cells [43].
Heteropolysaccharides are one of the bioactive molecules of Pleurotus ostreatus that control diabetes by activating the Glycogen synthase kinase 3 (GSK3) by phosphorylation and facilitating the translocation of glucose transporter type 4 (GLUT4) in streptozotocininduced diabetic rats [44]. Lentinula edodes promote the growth of gut microbiota, which play a very important role to balance the energy in diabetic patients. Another mushroom, Hirsutellas inensis shows antidiabetic, antiobesogenic effects in high-fat-diet feed-mice by modification of the components of gut microbiota. The polysaccharides and fibers of mushrooms act as prebiotics that helps in the treatment of diabetic patients [45]. Recently, researchers have found the potential effects of mushrooms in diabetic nephropathy conditions. Polysaccharides from Auricularia auricula are very helpful in promoting the oxidation of glucose. This polysaccharide protects against diabetic nephropathy by the regulation of creatinine, inflammatory factors, blood urea nitrogen, and urine protein. Polysaccharides isolated from Flammulina velutipes provided protection against reactive oxygen species (ROS) and reduced the level of malondialdehyde (MDA) in the kidney. The studies have also revealed that the proteoglycans from Ganoderma lucidum can restore kidney function by providing antioxidant activity [46]. According to a study conducted by Chou, Kan, Chang, Peng, Wang, Yu, Cheng, Jhang, Liu and Chuu [47], low molecular weight polysaccharide of Inonotus obiquus (LIOP) significantly reduces the expression of NF-jB and Transforming growth factor-beta (TGF-b) in a dose-dependent manner [48]. They find that LIOP treatment can improve glucolipotoxicity induced renal fibrosis in diabetic nephropathy mice. Hypsizigusm armoreus have been used to examine its protective effect on the liver, kidney, and pancreas. The spent mushroom compost polysaccharide (SCP), its enzymatic lysates (ESCP), and acid-based hydrolyzed SCP (ASCP) were tested in streptozotocin-induced mice and found that it increased the: catalase, superoxide dismutase, and glutathione peroxidase activity whereas, it reduced the lipid peroxide and malonaldehyde levels [49]. a-glucosidase inhibiting polysaccharide (ePS-F4-1) with triterpenoids had been purified from Coriolus versicolor. Another bioactive molecule, MT-a-glucan (polysaccharide) from Grifola frondosa increases the expression of Interleukin-2 (IL-2) and prevents the injury of b-cells [50]. Submerged cultured mycelium of Agaricus brasiliensis and G. lucidum has shown a protective effect on red blood cells (RBCs) in Streptozotocin (STZ)-induced diabetic rats [51].
4. Anticancer activity
Reproductive system diseases are responsible for several types of cancers like: prostate cancer, breast cancer, ovarian cancer, cervical cancer, uterine cancer, colorectal cancer etc. The bioactive compounds present in the mushroom are playing an important role in the treatment of reproductive disease-associated cancers. There are several medicinal mushrooms like Ganoderma lucidum, Trametes versicolor, Inonotus obliquus, Fomitopsis officinalis, etc. which are frequently used in the treatment of cancer. Prostate cancer is the third leading cause of cancer deaths in men worldwide and the utmost common male malignancy in several western countries. The incidence rate of prostate cancer is highest in the United States, lower in European countries and lowest in Asia [52]. The common risk factor related to prostate cancer is age, obesity, family history, environmental factors and dietary factors [53]. Retinoblastoma (Rb) and p53 (tumor suppressor gene) play a vital role in the progression of prostate cancer [54]. The anomalous expression in growth factors and receptors such as: transforming growth factor-a (TGF-a), epidermal growth factor (EGF), transforming growth factor-b (TGF-b), HER-2/neu, and c-erbB-3 oncogenes [41] also lead to the malignant prostate cancer. To combat these problems, natural compounds and fungal metabolites can be used as inhibitors for targeting cancerous cells in certain cancers [55, 56, 57, 58]. Ganoderma lucidum belongs to the Ganoderma genus, oriental medicinally mushroom, which have been widely used in Asian countries for centuries to cure different diseases including cancer. Plenty of species of this genus have antiviral, antibacterial, antifungal, anticancer, and immune-stimulating activities [59]. These activities were due to the production of various bioactive compounds present in medicinally mushrooms such as proteins [60, 61, 62], terpenes, sterols, and polyphenols, etc. The dried powder of G. lucidum is used as dietary supplements and is also used as a chemotherapeutic agent for cancer therapy. It induced the apoptosis of prostate cancer (PC-3) cells by lowering the expression of NF-jB-mediated Bcl-2 and Bcl-xl expression while the upregulation of the Bax protein [63]. The extracts of G. lucidum suppress the proliferation of cells and induce the G1 cell cycle in prostate cancer and breast cancer cells line [64]. Trametes versicolor, is a medicinal mushroom, belongs to the class Agaricomycetes shows anti-proliferative effects upon hepatocellular carcinoma cells (HCC), prostate cancer (DU145) and human breast cancer (4 T1) [42]. Several studies suggested that in T. versicolor β-glucan-based polysaccharopeptide fraction (PSP) and polysaccharide fraction (PSK) are present which are used as immunotherapeutic anticancer agents [65]. PSP activates cells of the immune system by enhancing the secretion of histamine, chemokines and cytokines such as interleukins (IL-1b and IL-6), TNF-a and prostaglandin E which excites dendrite and T-cell infiltration into tumor and lowers the damaging undesirable effects of chemotherapy [66]. Breast cancer is becoming one of the most common leading causes of mortality among women. The molecular subtypes of breast cancer are identified by gene expression profiles and lead to the identification of biomarkers that may ease the prognosis and treatment of cancer [67]. The molecular and pathological marker for the treatment of breast cancer is based on the presence or absence of progesterone receptors (PR), estrogen receptor (ER), and human epidermal growth factor receptor 2 (HER2) [67]. To overcome this problem, the medicinally mushroom is widely utilized in modern integrative oncology and given to patients regularly. The clinical results suggested that T. versicolor inhibits the human triple-negative breast cancer cells (MDA-MB-231) in the in vitro culture and reduced their growth [68] and is used as a supplement in the treatment of breast cancer. The mushroom Inonotus obliquus, often known as Chaga mushroom, belongs to the Agaricomycetes class and is widely used as traditional medicine for cancer therapy in Korea, China, Japan, and Russia [69]. Scientists illustrated that the water extracts of Chaga mushroom have shown cytotoxic and antimitotic activity on HeLa cells. The polysaccharides from I. obliquus inhibit the migration of cancer cell lines and shows anti-metastatic activities in vitro. The polysaccharide suppressed the NF-jB, PI3K/AKT and MAPKs signaling pathways by blocking activity and the expression of matrix metalloproteinases 2 and 9 (MMP) [70]. The studies confirmed that the Chaga mushroom has Wnt/β- catenin-inhibitory properties due to the presence of one major compound namely inotodiol which suppressed the breast cancer proliferation via the Wnt-dependent signaling pathway in a diabetic rat model [71].
The bioactive compounds present in the Ganoderma species are a viable alternative to fight breast cancer. The aqueous extracts of G. lucidum, G. sinense and G. tsugae were widely used against breast cancer cells. The data illustrated that the aqueous extract of these species has anti-proliferative activities against MCF-7 cells and MDA-MB-231 cells. However, the aqueous extract of G. tsugae was most effective against MCF-7 cells, although the activity of other Ganoderma species is similar to MDA-MB-231 cells. It also established that the extract did not show any cytotoxic activity against human noncancerous epithelial cells [72]. Several results showed that G. lucidum suppressed the proliferation of MDA-MB-231 cells in a dose and time-dependent manner [64]. The spore powder of G. lucidum also exhibited potent cytotoxic effects in the MDA-MB-468, triple-negative breast cancer cell lines, and SUM-102cell line and overexpressing the HER2 gene in MDA-MB435 [73]. Fomitopsis officinalis belongs to the family Polyporaceae and is generally known as ‘Agarikon.’ The fruiting bodies of mushrooms are used as a medicine in Western Europe, North America, and Asian countries for the treatment of gastric cancer, asthma, cough, and pneumonia [74]. Some auspicious evidence illustrated that using fungal extracts can help prevent breast and gastrointestinal cancers. Some studies confirmed antiviral, antibacterial, anticancer, and anti-inflammatory activity of crude extract of F. officinalis in different forms of cancers [75]. In F. officinalis extract, Lanostane-type triterpenoids, was reported which showed promising anticancer activity. Scientists showed that the ethanol extracts of F. officinalis are more effective in comparison with water extract against human breast cancer (MDAMB-231) cells, colon cancer (HCT-116), lung cancer (A549), mouse sarcoma 180 (S-180) and hepatoma (HepG2) cells [75].
Figure 4 shows the therapeutic activity of mushrooms and their biomolecules in the treatment of different forms of cancer. The immune system plays a very contributing role in the progression of tumors toward cancer. Mushroom shows its therapeutic activity by targeting the components of the immune system and also modulates the apoptotic processes. Figure 4 suggests the therapeutic activity of mushrooms by modulating the different components of the immune system and also regulates the apoptotic processes in cancerous cells [76, 77, 78].
Figure 4.
Antitumor mechanism of bioactive compounds in medicinal mushroom.
5. Biomolecules of mushrooms in neurodegenerative diseases (NDs)
Bioactive molecules in mushrooms also prevent the progression of different NDs. Motor symptoms linked with Parkinson’s disease (PD) are significantly prevented by a diet rich in mushroom supplements. In addition, the clinical symptoms of PD were also alleviated by mushroom supplements rich in phytochemicals, minerals, and vitamins [79]. Anti-inflammatory and antioxidative activity is exhibited by dietary mushrooms containing significant quantities of carotenoids, polysaccharides, minerals, polyphenols, and vitamins [80]. The two major factors that are responsible for the progression of PD are oxidative stress and neuroinflammation. Thus, the biomolecules present in edible mushrooms offer significant neuroprotection by their anti-oxidative and anti-inflammatory activity by preventing the progressive degeneration of dopaminergic neurons [79]. One of the major factors responsible for the generation of neuroinflammation in PD is the activation of microglial cells. Ganoderma lucidum extract (GLE) inhibited the activation of these microglial cells and ultimately preventing the progressive degeneration of dopaminergic neurons in PD. Tumor necrosis factoralpha (TNF-a) and interleukin-1b (IL-1b) are the examples of some important proinflammatory cytokines whose expression was downregulated by GLE in a dose-dependent manner and can be treated by natural antibiotics reported in [81]. Further progression of PD is prevented by inhibition of these proinflammatory cytokines by GLE. Thus, the treatment of PD, GLE should be utilized as an effective anti-inflammatory medication [82]. For the treatment of PD, niacin-rich food can be very beneficial and offers significant protective activity. Niacin-rich mushroom content offers potential therapeutic efficacy in the treatment of PD [83]. In the rotenone intoxicated model of PD, neuroprotective activity was shown by the Agaricus blazei extract (ABE). ABE also improves rotenone-induced non-motor and motor complications in PD. Therefore, for the treatment of PD, ABE might also be utilized as a nutritional supplement [84]. Some herbal plants like Tinospora cordifolia, Withania somnifera, Mucuna pruriens (Mp), and the essential oils also exhibit neuroprotective activity similar to mushrooms in toxin-induced PD mouse models [85, 86, 87]. In addition, bioactive components of Mp like Ursolic acid also exhibits potent antioxidative and anti-inflammatory property in toxin-induced PD model [88, 89, 90]. Chlorogenic acid also exhibits a similar AntiParkinsonian activity in the mouse model of PD [91]. Similar to PD, in Alzheimer’s disease (AD), nutritional mushroom provides important biomolecules that help to improve the quality of AD patients. Neuroinflammation along with oxidative stress mainly contributes to the pathogenesis of AD. The redox status in the cell of AD is significantly impaired [1]. Mushrooms have all the essential components that restore the normal balance of the redox system in AD models and patients. Proper and accurate functioning of mitochondria is required to maintain energy homeostasis. The synthesis of vital energy equivalents is hampered by abnormal mitochondrial functioning. In the neuroprotective network, inflammasome is an example of a very vital component. In AD, mitochondrial functioning was improved by Coriolus and Hericium. Normal redox balance was also maintained by these two nutritional mushrooms. Thus, energy homeostasis in AD was maintained by the above-mentioned two mushrooms by their antioxidative and anti-inflammatory properties [92]. One of the best examples of both medicinal and edible mushrooms is the Hericium erinaceus (HE). Both in vitro and in vivo model systems show the neuroprotective activity of HE. The aqueous extract of HE rich in a mycelium polysaccharide shows potent anti-apoptotic activity in l-glutamic acid (l-Glu)-induced differentiated PC12 (DPC12) cell lines. The AD mouse model induces by the combination of AlCl3 with D-galactose. The aqueous extract of HE prevents the further progression of AD by its neuroprotective potential. Behavioral abnormalities were also improved by the aqueous extract of HE in the AD mouse model. In a dosedependent manner, HE is responsible for the enhancement of choline acetyltransferase (ChAT) and acetylcholine (Ach) in serum and hypothalamus. To avert the pathogenesis of AD, the hypothalamus and serum level of Ach and ChAT is very vital. HE could be an efficient neuroprotective agent in AD and for some other neurodegenerative diseases [22]. For the treatment of different diseases, Coriolus versicolor (CV) mushroom is also widely utilized as a nutritional supplement. The oxidative stress and neuroinflammation were considerably reduced by the CV in AD. CV also improve the quality of mitochondria and restores the normal redox balance [92]. Human wellness was effectively maintained by the bioactive molecules present in prebiotics such as legumes [93, 94, 95], spirulina [96], biological nanoparticles [93, 97], mushroom [30]. Similar to PD, some herbal plants like Bacopa monnieri, Withania somnifera, Eclipta alba, Moringa oleifera and cucumber also improves cognitive function as suggested by some researchers [98, 99, 100, 101, 102, 103]. In addition, the neuroinflammatory pathways are also significantly modulated by a variety of medicinal mushrooms in AD [104]. In Huntington’s disease (HD), the therapeutic efficacy was also shown by medicinal, non-edible, and edible mushrooms and their bioactive components. Cognitive dysfunction is the very basic clinical feature of HD. In the edible mushroom Polyozellus multiplex, Polyozellin is a very important biomolecule having significant therapeutic activity. In the HD model, glutamate-induced mouse hippocampal neuronal HT22 cell death was significantly ameliorated by Polyozellin by apoptosis and the MAPK pathway. In HT22 cells, biochemical anomalies like lipid peroxidation and reactive oxygen species (ROS) were reduced by Polyozellin. Therefore, Polyozellin might be utilized for the treatment of HD patients in near future [105]. In the animal model of multiple sclerosis (MS), the disease conditions were ameliorated by Piwep, a mushroom extract from Phellinus igniarius. The dietary mushrooms and their bioactive components also improve the disease pathology in MS as with other NDs [106]. NFjB and Nrf2 mediated neuroinflammatory pathways are mainly responsible for mitochondrial dysfunction and ultimately cause progressive neurodegeneration in all NDs. Thus, the biomolecules of mushrooms play a very potential role to reduce the pathogenesis associated with NDs. Further studies will need to characterize more biomolecules in mushrooms and test their efficacy in several NDs.
\n',keywords:"mushroom, species, bioactive components, anticancer, antidiabetic",chapterPDFUrl:"https://cdn.intechopen.com/pdfs/81926.pdf",chapterXML:"https://mts.intechopen.com/source/xml/81926.xml",downloadPdfUrl:"/chapter/pdf-download/81926",previewPdfUrl:"/chapter/pdf-preview/81926",totalDownloads:10,totalViews:0,totalCrossrefCites:0,dateSubmitted:"February 26th 2022",dateReviewed:"March 2nd 2022",datePrePublished:"June 13th 2022",datePublished:null,dateFinished:"May 24th 2022",readingETA:"0",abstract:"Apposite energy is required for body activity. Energy is derived from the oxidation of various biomolecules like carbohydrates, lipids, and proteins. These bio-molecules in the proper amount are essential for the structural and functional activities of any living being. Certain vitamins and enzymes are also needed for the maintenance of biochemical processes. Our daily food is the major source of these biomolecules. From the last few decades, researchers have placed giant effort into searching for a food material that can provide nearly all the essential components required to maintain the energy need and consequently, balancing the body’s homeostasis. Mushrooms have the potential to address the above-raised issues. Besides their pleasant flavor and culinary value, mushrooms are an important source of biomolecules that include large macromolecules (protein, carbohydrate, lipid, and nucleic acid) as well as small molecules (primary metabolites, secondary metabolites, and natural products). This chapter discusses the bioactive compounds in edible mushroom and their activities.",reviewType:"peer-reviewed",bibtexUrl:"/chapter/bibtex/81926",risUrl:"/chapter/ris/81926",signatures:"Ahmed M. Saad, Mahmoud Z. Sitohy, Belal A. Omar, Mohamed T. El-Saadony and Basel Sitohy",book:{id:"11363",type:"book",title:"Functional Food",subtitle:null,fullTitle:"Functional Food",slug:null,publishedDate:null,bookSignature:"Dr. Naofumi Shiomi and Ph.D. Anna Savitskaya",coverURL:"https://cdn.intechopen.com/books/images_new/11363.jpg",licenceType:"CC BY 3.0",editedByType:null,isbn:"978-1-80355-793-9",printIsbn:"978-1-80355-792-2",pdfIsbn:"978-1-80355-794-6",isAvailableForWebshopOrdering:!0,editors:[{id:"163777",title:"Dr.",name:"Naofumi",middleName:null,surname:"Shiomi",slug:"naofumi-shiomi",fullName:"Naofumi Shiomi"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}},authors:null,sections:[{id:"sec_1",title:"1. Introduction",level:"1"},{id:"sec_2",title:"2. Mushroom active compounds against cardiovascular diseases (CVDs)",level:"1"},{id:"sec_3",title:"3. Antidiabetic activity of mushroom biomolecules",level:"1"},{id:"sec_4",title:"4. Anticancer activity",level:"1"},{id:"sec_5",title:"5. 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Department of Biochemistry, Faculty of Agriculture, Zagazig University, Egypt
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Department of Agricultural Microbiology, Faculty of Agriculture, Zagazig University, Egypt
Department of Radiation Sciences, Norrlands universitetssjukhus Umeå universitet, Sweden
Department of Clinical Microbiology, Infection and Immunology, Umeå University, Sweden
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CSIC affiliated authors can also take advantage of a central Open Access fund (amounting to 10,000 EUR) to cover up to 50% of the rest of the OAPF until it expires. Effective for chapters accepted from January 1, 2020.
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Corresponding authors will receive a 25% discount on their Open Access Publication Fees (OAPF) for Open Access book chapters. A 20% discount for publishing a long-form monographs, 25% for compacts and 23% for short-form monographs.
Corresponding authors will receive a 25% discount on their Open Access Publication Fees (OAPF) for Open Access book chapters. A 20% discount for publishing a long-form monographs, 25% for compacts and 23% for short-form monographs.
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The University of Surrey is pledging funds via the Knowledge Unlatched program to ensure academics can publish Open Access content more easily.
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Virginia Polytechnic Institute and State University
Corresponding authors will receive a 25% discount on their Open Access Publication Fees (OAPF) for Open Access book chapters. A 20% discount for publishing a long-form monographs, 25% for compacts and 23% for short-form monographs.
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CSIC affiliated authors can also take advantage of a central Open Access fund (amounting to 10,000 EUR) to cover up to 50% of the rest of the OAPF until it expires. Effective for chapters accepted from January 1, 2020.
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Corresponding authors will receive a 25% discount on their Open Access Publication Fees (OAPF) for Open Access book chapters. A 20% discount for publishing a long-form monographs, 25% for compacts and 23% for short-form monographs.
Corresponding authors will receive a 25% discount on their Open Access Publication Fees (OAPF) for Open Access book chapters. A 20% discount for publishing a long-form monographs, 25% for compacts and 23% for short-form monographs.
The Claremont Colleges are pledging funds via the Knowledge Unlatched program to ensure academics can publish Open Access content more easily.
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Corresponding authors will receive a 15% discount on their Open Access Publication Fees (OAPF) for Open Access book chapters or monograph publications. To use the discount you will need to verify your institutional email address. These discounts are valid from 2020 to 2022.
The University of Massachusetts, Amherst is pledging funds via the Knowledge Unlatched program to ensure academics can publish Open Access content more easily.
\n\n
Corresponding authors will receive a 10% discount on their Open Access Publication Fees (OAPF) for Open Access book chapters or monograph publications. To use the discount you will need to verify your institutional email address. These discounts are valid from 2020 to 2022.
The University of Surrey is pledging funds via the Knowledge Unlatched program to ensure academics can publish Open Access content more easily.
\n\n
Corresponding authors will receive a 10% discount on their Open Access Publication Fees (OAPF) for Open Access book chapters or monograph publications. To use the discount you will need to verify your institutional email address. These discounts are valid from 2020 to 2022.
\n\n
\n\t
Virginia Polytechnic Institute and State University
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I had been a visiting research student at Faculty of Computer Science, University of Murcia, Murcia, Spain for three months.\n\nI have published over 40 papers during 5 years in refereed journals, books, and conference proceedings in the areas of electro-physiological signals processing and classification, notably EMG and EOG signals, fractal analysis, wavelet analysis, texture analysis, feature extraction and machine learning algorithms, and assistive and rehabilitative devices. I have several computer programming language certificates, i.e. Sun Certified Programmer for the Java 2 Platform 1.4 (SCJP), Microsoft Certified Professional Developer, Web Developer (MCPD), Microsoft Certified Technology Specialist, .NET Framework 2.0 Web (MCTS). I am a Reviewer for several refereed journals and international conferences, such as IEEE Transactions on Biomedical Engineering, IEEE Transactions on Industrial Electronics, Optic Letters, Measurement Science Review, and also a member of the International Advisory Committee for 2012 IEEE Business Engineering and Industrial Applications and 2012 IEEE Symposium on Business, Engineering and Industrial Applications.",institutionString:null,institution:{name:"Joseph Fourier University",country:{name:"France"}}},{id:"55578",title:"Dr.",name:"Antonio",middleName:null,surname:"Jurado-Navas",slug:"antonio-jurado-navas",fullName:"Antonio Jurado-Navas",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",biography:"Antonio Jurado-Navas received the M.S. degree (2002) and the Ph.D. degree (2009) in Telecommunication Engineering, both from the University of Málaga (Spain). He first worked as a consultant at Vodafone-Spain. From 2004 to 2011, he was a Research Assistant with the Communications Engineering Department at the University of Málaga. In 2011, he became an Assistant Professor in the same department. From 2012 to 2015, he was with Ericsson Spain, where he was working on geo-location\ntools for third generation mobile networks. Since 2015, he is a Marie-Curie fellow at the Denmark Technical University. 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