Summary statistics of sampled farmers in KwaZulu-Natal (n=200)
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The practice of organic agriculture has been identified as a pathway to sustainable development and enhancing food security. Arguably, the most sustainable choice for agricultural development and food security is to increase total farm productivity
Expectedly, a paradigm shift towards this realization of organic agriculture’s role in food and nutritional security is emerging [5]. The United Nations Environmental Programme-United Nations Conference on Trade and Development, UNEP-UNCTAD [6] indicates that organic agriculture offers developing countries a wide range of economic, environmental, social and cultural benefits. On the development side, organic production is particularly well-suited for smallholder farmers, who make up the majority of the worlds’ poor. Resource poor farmers are less dependent on external resources, experience higher yields on their farms and enjoy enhanced food security [7]. Organic agriculture in developing countries builds on and keeps alive their rich heritage of traditional knowledge and traditional land races. It has been observed to strengthen communities and give youth incentive to keep farming, thus reducing rural-urban migration. Farmers and their families and employees are no longer exposed to hazardous agro-chemicals, which is one of the leading causes of occupational injury and death in the world [7].
As organic production increases, so does the interest in organic market dynamics and studies are being carried out in order to analyse the future potential for organic agriculture. Figure 1 shows the global markets for certified organic products. In 2009, the global market for certified organic food and drink was estimated to be 54. 9 billion US dollars [8]. This represents a 37% growth from 2006 sales estimated at 40. 2billionUS dollars and a 207% increase from year 2000 sales estimated at17. 9 billion US dollars. In Africa, most of the organic farms are small family smallholdings [9] and certified organic production is mostly geared to products destined for export beyond Africa’s shores. However, local markets for certified organic products are growing, especially in Egypt, South Africa, Uganda and Kenya [10]. Figure2 shows the ten countries in Africa with the largest proportion of land allocated to organic agriculture. South Africa has the third largest area under organic farming with 50, 000 hectares (ha), trailing Tunisia which has the largest area of 154, 793ha and Uganda with 88, 439ha [11]. Approximately 20% of the total area under certified organic farming in Africa is in South Africa, with 250 certified commercial farms [12]. With a few exceptions, notably Uganda, most African countries do not have data collection systems for organic farming and certified organic farming is relatively underdeveloped, even in comparison to other low-income continents. Some expert opinions suggest that this is due to lack of awareness, low-income levels, lack of local organic standards and other infrastructure for local market certification [13].
Development of the global market for organic products
The ten countries in Africa with the most organic agricultural land in hectares
In 1999, only 35 farms were certified in South Africa, whereas in 2000 this number had increased to approximately 150 [15]. GROLINK [16] estimates that 240 farms with a total area of 43 620 ha (including pastures and in-conversion land) were certified in 2002. Certified organic produce in South Africa started with mangoes, avocadoes, herbs, spices, rooibos tea and vegetables [17]. This has now expanded to include a much wider range of products. Organic wines, olive oil and dairy products are now being produced [18]. The Organic Agricultural Association of South Africa (OAASA) estimates that there are approximately 100 non-certified farmers, farming about 1000hectares, following organic principles, who market informally through local villages or farmers markets (
South Africa has had an organic farming movement dating back many years, although it has grown in “fits and starts” [19]. Organic approaches have to make a trade off between market oriented commercial production and increasing the productive capacity of marginalized communities [20]. The growth of the organic industry has resulted in organic farming being practised in the Western Cape, KwaZulu-Natal, Eastern Cape, Northern Cape and Gauteng Province (Table 1). As discussed by [21] and [22] changing consumer preferences towards more health and environmental awareness has led to an increase in the demand for products produced using sustainable production methods. GROLINK [16] states that South Africa has in contrast with other Sub-Saharan countries, a substantial domestic market for organic products. This is an indication that the potential for organic farming in South Africa is not only based on access to the export market in Europe and the USA but also on the local demand. The domestic market is robust with two domestic retailers (Woolworth and Pick ‘n’ Pay) selling reasonable amounts of organic produce and both are now starting to insist on certification for this produce as well as farmers markets attracting large number of buyers.
One approach taken to improve smallholder access to organic markets has been the formation of certified organic groups using guidelines developed by the International Federation of Organic Agriculture Movement (IFOAM) and enforced by certification agencies such as Ecocert/AFRISCO (African Farmers Certified Organic) in the case of South Africa [23]. Under the group certification system, organic farmers can either grow and market their produce collectively or produce individually but market collectively. This ensures that smallholder farmers especially in developing countries are not marginalised and unduly excluded from the organic sector due to factors beyond their control. Several organic farming groups have emerged in South Africa in the last decade notably Ezemvelo Farmers Organization (EFO), Vukuzakhe Organic Farmers Organization (VOFO), Ikusasalethu Trust and Makhuluseni Organic Farmers Organisation.
The question of how to face the growing problem of food insecurity in Africa becomes more and more important, especially due to the steadily increasing world population and the changing consumption pattern. According to [24], while organically produced food seems not to be able to feed the World’s Population, there are strong evidences that organic agriculture might help to alleviate the number of people suffering from hunger especially in developing countries. Given the strong negative externalities of conventional agriculture, the diversification of production as a basic principal of organic agriculture can contribute to the improvement of food security [25] which may improve the nutritional level in rural communities. The expanding global market for organic products [26, 27] and the possibilities for smallholder farmers in developing countries to access markets [24] can have very positive effects on the rural economies, triggering rural development. The increasing awareness of what people consume also has positive effects on organic agriculture as an alternative option for agricultural production. Organic agriculture may thus be an option in some areas to strongly support rural development.
Against this background, the objective of this paper is to provide, through an exploratory analysis of data from farm and households surveys, empirical insights into determinants of organic farming adoption, differentiating between fully-certified organic, partially-certified organic and non-organic farmers; eliciting farmers risk preferences and management strategies and; exploring consumer awareness, perceptions and consumption decisions. By exploring a combination of adoption relevant factors in the context of real and important land management choices, the paper provides an empirical contribution to the adoption literature and provides valuable pointers for the design of effective and efficient public policy for on-farm conservation activities. Similarly, achieving awareness and understanding the linkage between awareness and purchasing organics is fundamental to impacting the demand for organically grown products. Consumer awareness of organic foods is the first step in developing demand for organic. Section 3 describes the materials and methods, outlining the study areas and study methodology. Section 4 presents the results and discussion. Finally, section5 provides concluding remarks.
The study was carried out in the two provinces of KwaZulu-Natal and the Eastern Cape Provinces in South Africa (Figure 3). The selected study areas are in the rural Umbumbulu Magisterial District in KwaZulu-Natal Province and the OR Tambo and Amatole District Municipalities in the Eastern Cape Province.
Map of study area
The Umbumbulu area is one of the former homelands of KwaZulu-Natal Province. The Province has the largest concentration of people who are relatively poor, and social indicators point to below average levels of social development. According to the mid-year population estimates by Statistics South Africa [28], the Province has a population of 10. 6 Million people 67 percent of whom reside in communal areas of the former KwaZulu-Natal homeland [28]. The OR Tambo District Municipality is the second poorest Municipality in the Eastern Cape Province with some areas having poverty levels of as high as 82 % [29]. About 67% of the households within the district have income levels that range between R0 and R6, 000. The District Municipality has the second highest population of all the districts with more than 1, 504, 411 inhabitants [29]. For a mostly rural district it also has a high population density of 90 people per square kilometre. The Amatole District Municipality is named after the legendary Amatole Mountains and is the most diverse District Municipality in the Province. Two-thirds of the District is made up of ex-homeland areas. The District has a moderate Human Development Index of 0. 52 with over 1, 635, 433 inhabitants [30], and a moderately high population density of 78 people per square kilometre. The population is mainly African with some whites and coloureds. Amatole District Municipality has the second highest economy in the province.
The Eastern Cape Province is bordering KwaZulu-Natal with similarities in the socio-economic status and rurality of the two Provinces. Both Provinces’ economic dependence is on agriculture with huge potential for organic agriculture development. The Eastern Cape is also a major consumer of produce from KwaZulu-Natal. A total of 400 respondents were interviewed, representing 200 farmer respondents from KwaZulu-Natal and 200 consumer respondents from Eastern Cape Provinces. The survey farmers in Umbumbulu District, KwaZulu-Natal were stratified into three groups: fully-certified organic farmers, partially-certified organic farmers and non-organic farmers. While the 48 fully-certified farmers and 103 partially-certified farmers were purposively selected, the sample of 49 non-organic farmers was randomly selected within the same region from a sample frame constructed from each of the five neighbouring wards. The survey was conducted by a team of trained enumerators from the study area. These enumerators had to be fluent in both English and Zulu. A questionnaire was used to record all household activities (farm and non-farm), enterprise types, crop areas and production levels, inputs, expenditures and sales for the past season. The questionnaires also captured socio-economic and institution data such as household characteristics, land size and tenure arrangements, farm characteristics and investment in assets. Other questions related to farmers’ management capacity and demographic characteristics such as the supply of on-farm family labour and education status.
The farmers’ risk attitude was elicited using the experimental gambling approach as outlined by [31]. Here, the study farmers were presented with a series of choices among sets of alternative prospects (gambles) that do not involve real money payments. Respondents were required to make a simple choice among eight gambles whose outcomes were determined by a flip of a coin. The experimental approach remedies some of the more serious measurement flaws of the direct elicitation utility (DEU) interview method reporting that evidence on risk aversion using direct elicitation utility through pure interviews is unreliable, nonreplicable and misleading even if one is interested only in a distribution of risk aversion rather than reliable individual measurements [31, 32]. The farmers were further asked in the field survey to give their perceptions of the main sources of risk that affect their farming activity by ranking a set of 20 potential sources of risk on like rt-type scales ranging from 1 (no problem) to 3 (severe problem). These sources of risk were developed from findings of the research survey and from past research on the sources of risk in agriculture, challenges that smallholder farmers face in trying to access formal supply chains. The farmers were also requested to score any other sources of risk(s) that they wanted to add to the list of hypothesized sources of risk. These sources of risk are ranked from 1 (being the most important source of risk) to 20(being the least important source of risk ones). The ranking was done by averaging the scores on each source of risk and assigning a rank accordingly.
The study area in the Eastern Cape was stratified into the OR Tambo District Municipality and the Amatole District Municipality representing a broad spectrum of consumers across the Province. The stratified study areas were further clustered into rural, peri-urban and urban areas. The respondents were selected by simple random sampling to avoid bias. A total of 100 consumers were selected from OR Tambo District Municipality and represented by a selection of 30 respondents from peri-urban location, 40 respondents from urban suburbs and 30 respondents from rural areas. In the Amatole District Municipality, 100 consumers selected and interviewed included 30 respondents from rural Cata, 40 urban respondents from the East London Suburbs and lastly 30 respondents drawn from the peri urban area of Kwezana and Tsathu villages. A structured questionnaire was used that covered the respondent’s socio-economic and demographic background, consumer knowledge and awareness of organic products, perceptions, attitudes as well as consumption decisions.
The ordered probit model was used to identify the determinants of farmers’ decision to participate in organic farming. The dependent variable is the farmer’s organic farming status and was placed in three ordered categories in the survey. The model is estimated as:
The organic farming status is modelled using the ordered probit model with the model outcomes:
Si=3 (fully-certified organic),
Si=2 (partially-certified organic farming) and
Si=1 (non-organic farmers).
The farmer’s decision on their organic farming status is unobserved and is denoted by the latent variable si*. The latent equation below models how si* varies with personal characteristics and is represented as:
Where:
the latent variable
(
the error term
The observed variable (Si) relates to the latent variable (si*) such that
Taking the value of 3 if the individual was fully-certified organic and 1 if the individual was non-organic. The implied probabilities are obtained as:
Where γ is the unknown parameter that is estimated jointly with α. Estimation is based upon the maximum likelihood where the above probabilities enter the likelihood function. The interpretation of the α coefficients is in terms of the underlying latent variable model in equation 11.
The probability of the farmer being fully-certified organic can be written as
Where Φ( ) is the cumulative distribution function (cdf) of the standard normal [33].
A measure of goodness of fit can be obtained by calculating
Where ln
Where K is the number of parameter estimates in the model (degrees of freedom)
For the experimental gambling approach, the utility function with Constant Partial Risk Aversion (CPRA) is used to get a unique measure of partial risk aversion coefficient for each game level. This depicted as the equation below:
The Herfindahl Index (DHI) is used to calculate enterprise diversification and represent the specialization variable. Although, this index is mainly used in the marketing industry to analyze market concentration, it has also been used to represent crop diversification [35, 36]. Herfindhal index (DHI) is the sum of square of the proportion of individual activities in a portfolio. With an increase in diversification, the sum of square of the proportion of activities decreases, so also the indices. In this way, it is an inverse measure of diversification, since the Herfindhal index decreases with an increase in diversification. The Herfindhal index is bound by zero (complete diversification) to one (complete specialization).
The summary statistics in Table 1 show that the average age of the farmers was over 50 years with younger people migrating to urban centres in search of better jobs. In the study area, most of the men are engaged in wage employment at the neighbouring sugarcane farms or as migrant workers in the cities of Durban, Johannesburg. Hence over 70% of the farmers were female. Education levels are low and are consistent with most rural farming communities in South Africa, where formal education opportunities are limited. Household sizes were large with family labour playing a major role in tilling the land. Small farm sizes averaging 0. 59 hectares for fully-certified organic farmers, 0. 67 hectares for non-organic farmers and 0. 71 hectares for partially-certified farming was common in KwaZulu-Natal.
The main sources of income were farm and off farm employment, the latter constituting wages or salary income and remittances. Farm income was highest for fully-certified organic farmers. This is an indication that the adoption of fully-certified organic farming and its commercialization has brought economic benefits to these otherwise poor rural households and is an important contributor to household income. The proportion of income from farming was highest among the fully certified organic farmers. While the average farmer was classified as risk averse, non-organic farmers were more risk averse than their organic counterparts. Risk-averse farmers are reluctant to invest in innovations of which they have little first-hand experience. Despite the tenure system being communal, farmers felt they had tenure rights through the permission to occupywith allocation done by the traditional chief of the tribe (
\n\t\t\t | ||||||
Age (years) | \n\t\t\t52.60 | \n\t\t\t1.90 | \n\t\t\t48.60 | \n\t\t\t1.41 | \n\t\t\t52.70 | \n\t\t\t2.11 | \n\t\t
Gender (1=female) | \n\t\t\t0.82 | \n\t\t\t0.05 | \n\t\t\t0.71 | \n\t\t\t0.05 | \n\t\t\t0.84 | \n\t\t\t0.05 | \n\t\t
Education (years) | \n\t\t\t4.94 | \n\t\t\t4.24 | \n\t\t\t4.37 | \n\t\t\t4.49 | \n\t\t\t3.38 | \n\t\t\t0.61 | \n\t\t
Household size | \n\t\t\t9.49 | \n\t\t\t5.23 | \n\t\t\t7.72 | \n\t\t\t3.68 | \n\t\t\t6.60 | \n\t\t\t3.46 | \n\t\t
Land size (hectares) | \n\t\t\t0.59 | \n\t\t\t1.22 | \n\t\t\t0.71 | \n\t\t\t1.16 | \n\t\t\t0.67 | \n\t\t\t1.43 | \n\t\t
Input costs (rand/year) | \n\t\t\t812.90 | \n\t\t\t884.90 | \n\t\t\t309.30 | \n\t\t\t343.40 | \n\t\t\t318.20 | \n\t\t\t302.90 | \n\t\t
Proportion of income from farming | \n\t\t\t0.62 | \n\t\t\t0.79 | \n\t\t\t0.38 | \n\t\t\t1.04 | \n\t\t\t0.39 | \n\t\t\t0.63 | \n\t\t
Farm income (rands/year) | \n\t\t\t973.17 | \n\t\t\t1074.51 | \n\t\t\t417.26 | \n\t\t\t271.50 | \n\t\t\t400.53 | \n\t\t\t429.53 | \n\t\t
Location | \n\t\t\t2.56 | \n\t\t\t0.60 | \n\t\t\t1.91 | \n\t\t\t0.54 | \n\t\t\t4.00 | \n\t\t\t0.00 | \n\t\t
Arrow Pratt Risk Aversion coefficient | \n\t\t\t0.55 | \n\t\t\t0.29 | \n\t\t\t0.58 | \n\t\t\t0.31 | \n\t\t\t0.76 | \n\t\t\t0.29 | \n\t\t
Land rights (0 = no) | \n\t\t\t1.98 | \n\t\t\t0.14 | \n\t\t\t1.75 | \n\t\t\t0.56 | \n\t\t\t1.93 | \n\t\t\t0.33 | \n\t\t
Chicken ownership | \n\t\t\t15.29 | \n\t\t\t13.16 | \n\t\t\t9.25 | \n\t\t\t8.69 | \n\t\t\t6.40 | \n\t\t\t6.62 | \n\t\t
Asset ownership (index) | \n\t\t\t0.98 | \n\t\t\t0.60 | \n\t\t\t0.56 | \n\t\t\t0.59 | \n\t\t\t0.67 | \n\t\t\t0.75 | \n\t\t
Summary statistics of sampled farmers in KwaZulu-Natal (n=200)
The ordered probit model results are presented in Table 2. The model successfully estimated the significant variables associated with the farmer’s adoption decisions. The Huber/White/sandwich variances estimator was used to correct for heteroscedasticity. The explanatory variables collectively influence the farmer’s decision to be a certified organic with the chi-square value significant at one percent. The following variables were found to be significant determinants in the organic farming adoption decision by smallholder farmers in the study area: age, household size, land size, locational setting of the farmer depicted by the sub-wards Ogagwini, Ezigani, and Hwayi, farmer’s risk attitude, livestock ownership (chicken and goat ownership), land tenure security as depicted by the rights the farmer can exercise on his/her own cropland to build structures and asset ownership.
\n\t\t\t\t | \n\t\t\t\n\t\t\t\t | \n\t\t\t\n\t\t\t\t | \n\t\t\t\n\t\t\t\t | \n\t\t
Age | \n\t\t\t0.0194072 | \n\t\t\t0.0079204 | \n\t\t\t0.014*** | \n\t\t
Gender | \n\t\t\t0.3796234 | \n\t\t\t0.2707705 | \n\t\t\t0.161 | \n\t\t
Household size | \n\t\t\t0.0504668 | \n\t\t\t0.0271520 | \n\t\t\t0.063* | \n\t\t
Land size | \n\t\t\t-0.2352607 | \n\t\t\t0.1083583 | \n\t\t\t0.030** | \n\t\t
Off Farm Income | \n\t\t\t-0.0001223 | \n\t\t\t0.0001129 | \n\t\t\t0.279 | \n\t\t
\n\t\t\t\t | \n\t\t\t\n\t\t\t | \n\t\t\t | \n\t\t |
Location (1= ogagwini) | \n\t\t\t2.894311 | \n\t\t\t0.6380815 | \n\t\t\t0.000*** | \n\t\t
Location (1=ezigani) | \n\t\t\t4.191274 | \n\t\t\t0.7234394 | \n\t\t\t0.000*** | \n\t\t
Location (1=hwayi) | \n\t\t\t5.158803 | \n\t\t\t0.8495047 | \n\t\t\t0.000*** | \n\t\t
Risk attitudes | \n\t\t\t-0.759508 | \n\t\t\t0.3773067 | \n\t\t\t0.044** | \n\t\t
\n\t\t\t\t | \n\t\t\t\n\t\t\t | \n\t\t\t | \n\t\t |
Chicken ownership | \n\t\t\t0.0424046 | \n\t\t\t0.0148472 | \n\t\t\t0.004*** | \n\t\t
Cattle ownership | \n\t\t\t-0.0418692 | \n\t\t\t0.0431078 | \n\t\t\t0.331 | \n\t\t
Goat ownership | \n\t\t\t-0.1005212 | \n\t\t\t0.0569375 | \n\t\t\t0.077* | \n\t\t
\n\t\t\t\t | \n\t\t\t\n\t\t\t | \n\t\t\t | \n\t\t |
Land tenure (1= build structures) | \n\t\t\t0.4803418 | \n\t\t\t0.2372247 | \n\t\t\t0.043** | \n\t\t
Land tenure (1= plant trees) | \n\t\t\t0.0235946 | \n\t\t\t0.3023182 | \n\t\t\t0.938 | \n\t\t
Land tenure (1= bequeath) | \n\t\t\t0.1335225 | \n\t\t\t0.2619669 | \n\t\t\t0.610 | \n\t\t
Land tenure (1= lease out) | \n\t\t\t-0.3840883 | \n\t\t\t0.2593139 | \n\t\t\t0.139 | \n\t\t
Land tenure (1= sell land) | \n\t\t\t0.0829177 | \n\t\t\t0.2978485 | \n\t\t\t0.781 | \n\t\t
Asset ownership | \n\t\t\t0.5853967 | \n\t\t\t0.205389 | \n\t\t\t0.004*** | \n\t\t
Adoption of organic farming among smallholder farmers: Ordered probit model results
(Source: Field Data)
The study established that older female farmers with large household sizes were more likely to be certified-organic. Similarly, farmers who reside in the sub-wards Ogagwini, Ezigani, and Hwayi were more likely to be certified organic. This suggests the presence of local synergies in adoption which raises the question about the extent to which ignoring these influences biases policy conclusions. The negative correlation between land size and adoption implies that smaller farms appear to have greater propensity for adoption of certified organic farming. This finding is supported by several studies reviewed in the literature that allude to the fact that organic farms tend to be smaller than conventional farms. The significance of livestock is explained by the importance of manure for organic farming. The study also found that older farmers tend to be adopters supporting findings by [37]. The propensity to adopt was also positively influenced by asset index which is a proxy for wealth.
The distribution of risk aversion preferences for each prospect for the fully-certified organic, partially-certified organic and non-organic crop farmers are presented in Table 3. The distribution of responses was spread across all classes of risk aversion for the pooled data. It can be noted that on average, the majority of the respondents revealed their preference for prospects representing intermediate and moderate risk aversion alternatives across the three farmer groups. Table 3 further shows that non-organic farmers were the most risk averse being classified as extremely risk averse at 20. 4%, compared to fully and partially-certified organic farmers at 7. 3% and 4. 2%, respectively. This explains their non-adoption of certified organic farming, despite its introduction in the area since the year 2000. On the other hand, the fully-certified organic farmers were the least risk averse, being classified as neutral to risk preferring at 9. 1% compared to 7. 3% and 4. 1% for the partially certified and non-organic farmers respectively. These results conform to
Fully certified organic (n = 48) | \n\t\t\t7.30 | \n\t\t\t5.50 | \n\t\t\t30.90 | \n\t\t\t40.00 | \n\t\t\t7.30 | \n\t\t\t9.10 | \n\t\t
Partially certified organic(n = 95) | \n\t\t\t4.20 | \n\t\t\t8.30 | \n\t\t\t44.80 | \n\t\t\t29.20 | \n\t\t\t5.20 | \n\t\t\t7.30 | \n\t\t
Non-organic (n= 46) | \n\t\t\t20.40 | \n\t\t\t8.20 | \n\t\t\t30.60 | \n\t\t\t30.60 | \n\t\t\t0.00 | \n\t\t\t4.10 | \n\t\t
Pooled data (n = 189) | \n\t\t\t9.00 | \n\t\t\t7.50 | \n\t\t\t37.50 | \n\t\t\t32.50 | \n\t\t\t4.50 | \n\t\t\t7.00 | \n\t\t
Distribution of smallholder farmers according to risk preference patterns in KwaZulu-Natal
Source: Field data
According to Figure 4, the non-organic farmers constituted 55. 6% of respondents within the extreme risk aversion class compared to 22. 2% for fully-certified organic and 22. 2% for partially-certified organic farmers. This is a confirmation of previous findings in this study that explains the non-adoption of certified organic farming by the non-organic farmers. In the risk neutral to preferring category, the non-organic farmers constitute only 14. 3%. Fully-certified organic farmers constituted 57. 1% and partially-certified organic farmers constituted 28. 6%.
Frequency distribution within risk aversion classes across the farmer groups
A comparison of the results from the South African study, which applied the general experimental method, with similar studies using the same methodology was for farming communities in the Côte d’Ivoire [38], Ethiopia [39], Zambia [40], Philippines [41] and India [31], shows similarities in the findings of the studies done in India, Philippines, Zambia and Côte d’Ivoire, where the majority of the respondents are classified as intermediate to moderate risk aversion (Table 4). Similarly, these results suggest that farm households in South Africa are less risk averse than in Ethiopia, Zambia and Côte d’Ivoire but are much more risk averse than in India and Philippines.
India [31] | \n\t\t||||
50 rupee | \n\t\t\t8.4 | \n\t\t\t\n\t\t\t\t | \n\t\t\t9.4 | \n\t\t\t107 | \n\t\t
500 rupee | \n\t\t\t16.5 | \n\t\t\t\n\t\t\t\t | \n\t\t\t0.9 | \n\t\t\t115 | \n\t\t
Philippines [41] | \n\t\t||||
50peso | \n\t\t\t10.2 | \n\t\t\t\n\t\t\t\t | \n\t\t\t16.3 | \n\t\t\t49 | \n\t\t
500peso | \n\t\t\t8.1 | \n\t\t\t\n\t\t\t\t | \n\t\t\t14.3 | \n\t\t\t49 | \n\t\t
Zambia [40] | \n\t\t||||
1000kw | \n\t\t\t29.1 | \n\t\t\t\n\t\t\t\t | \n\t\t\t24.5 | \n\t\t\t423 | \n\t\t
10000kw | \n\t\t\t36.7 | \n\t\t\t\n\t\t\t\t | \n\t\t\t11 | \n\t\t\t137 | \n\t\t
Ethiopia [39] | \n\t\t||||
5bir | \n\t\t\t\n\t\t\t\t | \n\t\t\t33.6 | \n\t\t\t21 | \n\t\t\t262 | \n\t\t
15bir | \n\t\t\t\n\t\t\t\t | \n\t\t\t27.5 | \n\t\t\t16.8 | \n\t\t\t262 | \n\t\t
Côte d’Ivoire [38] | \n\t\t||||
1000FCFA | \n\t\t\t32.8 | \n\t\t\t\n\t\t\t\t | \n\t\t\t13.3 | \n\t\t\t362 | \n\t\t
5000FCFA | \n\t\t\t\n\t\t\t\t | \n\t\t\t45.9 | \n\t\t\t8 | \n\t\t\t362 | \n\t\t
*South Africa [42] | \n\t\t||||
400Rands | \n\t\t\t16.5 | \n\t\t\t\n\t\t\t\t | \n\t\t\t11.5 | \n\t\t\t196 | \n\t\t
Percentage distribution of revealed risk preferences in five experimental studies
*Source: Field work
Farmers identified their sources of risk and significance in terms of the potential impact to their farming activity as presented in Table 5. The fully-certified organic farmers cited in order of priority, uncertain climate (mean 2. 96), lack of cash and credit to finance inputs (mean 2. 78) and tractor unavailability when needed (mean 2. 76). These risk sources have a direct bearing on production of organic produce. Climatic conditions are beyond the farmers’ control, and the top ranking probably reflects the farmers’ concerns about the effects of recent drought in the Umbumbulu district. These impacts negatively on crop yield. Due to communal land ownership and strict conditions for credit, farmers have limited options to obtain production credit from financial institutions. Among the sampled farmers only 21 farmers were able to access credit. Farmers in the study area lack collateral that is acceptable to banks. For example, banks required title deeds as proof of land ownership but the majority of black farmers in South Africa and especially in the former homelands still lacked this vital documentation. Tractor unavailability can be attributed to the fact that there is one tractor that has been allocated to the members of Ezemvelo Farmers Organisation. The tractor is leased out at a rental fees. This poses a challenge during the land preparation phase when the demand for its services is at peak.
Similarly, partially-certified farmers also ranked tractor not being available when needed (mean 2. 89) and uncertain climate (mean 2. 83) as identified sources of risk (Table 5). The risk of delays in payment for products sent to pack house (mean 2. 89) are attributed to various factors, among them the contractual obligation the agent has with the retailer which has a bearing on the duration of payment. Payment is only made to the farmer once the supply has been forwarded to the retailer and there is confirmation of the quantity of produce that has been rejected. The process flow delays payments to farmers. Non-organic farmers also cited uncertain climate (mean 2. 82), livestock damage to crops (mean 2. 80) and lack of cash and credit to finance farm inputs (mean 2. 78). The livestock damage is a result of lack of fencing around the crops planted.
\n\t\t\t | |||||||||
Livestock damage | \n\t\t\t2.56 | \n\t\t\t0.774 | \n\t\t\t7 | \n\t\t\t2.82 | \n\t\t\t0.448 | \n\t\t\t4 | \n\t\t\t2.8 | \n\t\t\t0.539 | \n\t\t\t2 | \n\t\t
Uncertain climate | \n\t\t\t2.96 | \n\t\t\t0.189 | \n\t\t\t1 | \n\t\t\t2.83 | \n\t\t\t0.409 | \n\t\t\t3 | \n\t\t\t2.82 | \n\t\t\t0.486 | \n\t\t\t1 | \n\t\t
Uncertain prices for products sold to pack house | \n\t\t\t2.21 | \n\t\t\t0.793 | \n\t\t\t13 | \n\t\t\t2.13 | \n\t\t\t0.591 | \n\t\t\t16 | \n\t\t\t- | \n\t\t\t- | \n\t\t\t- | \n\t\t
Uncertain prices for products sold to other markets | \n\t\t\t1.94 | \n\t\t\t0.811 | \n\t\t\t17 | \n\t\t\t2.02 | \n\t\t\t0.595 | \n\t\t\t18 | \n\t\t\t2.17 | \n\t\t\t0.761 | \n\t\t\t10 | \n\t\t
Huge work load | \n\t\t\t2.58 | \n\t\t\t0.599 | \n\t\t\t6 | \n\t\t\t2.32 | \n\t\t\t0.688 | \n\t\t\t12 | \n\t\t\t2.53 | \n\t\t\t0.649 | \n\t\t\t4 | \n\t\t
Lack of cash and credit to finance inputs | \n\t\t\t2.78 | \n\t\t\t0.567 | \n\t\t\t2 | \n\t\t\t2.58 | \n\t\t\t0.615 | \n\t\t\t6 | \n\t\t\t2.78 | \n\t\t\t0.468 | \n\t\t\t3 | \n\t\t
Lack of information about producing organic crops | \n\t\t\t2.02 | \n\t\t\t0.687 | \n\t\t\t15 | \n\t\t\t2.2 | \n\t\t\t0.632 | \n\t\t\t14 | \n\t\t\t2.16 | \n\t\t\t0.717 | \n\t\t\t11 | \n\t\t
Lack of information about alternative markets | \n\t\t\t2.38 | \n\t\t\t0.623 | \n\t\t\t10 | \n\t\t\t2.29 | \n\t\t\t0.602 | \n\t\t\t13 | \n\t\t\t- | \n\t\t\t- | \n\t\t\t- | \n\t\t
Lack of proper storage facilities | \n\t\t\t2.56 | \n\t\t\t0.66 | \n\t\t\t7 | \n\t\t\t2.46 | \n\t\t\t0.543 | \n\t\t\t9 | \n\t\t\t2.41 | \n\t\t\t0.643 | \n\t\t\t7 | \n\t\t
Lack of affordable transport for products | \n\t\t\t2.72 | \n\t\t\t0.492 | \n\t\t\t4 | \n\t\t\t2.42 | \n\t\t\t0.56 | \n\t\t\t11 | \n\t\t\t2.06 | \n\t\t\t0.852 | \n\t\t\t12 | \n\t\t
Lack of telephone to negotiate sales | \n\t\t\t2.69 | \n\t\t\t0.509 | \n\t\t\t5 | \n\t\t\t2.55 | \n\t\t\t0.633 | \n\t\t\t8 | \n\t\t\t2.22 | \n\t\t\t0.771 | \n\t\t\t8 | \n\t\t
Inputs not available at affordable prices | \n\t\t\t2.52 | \n\t\t\t0.642 | \n\t\t\t9 | \n\t\t\t2.8 | \n\t\t\t0.447 | \n\t\t\t5 | \n\t\t\t2.51 | \n\t\t\t0.545 | \n\t\t\t5 | \n\t\t
Tractor not available when needed | \n\t\t\t2.76 | \n\t\t\t0.501 | \n\t\t\t3 | \n\t\t\t2.89 | \n\t\t\t0.416 | \n\t\t\t1 | \n\t\t\t2.46 | \n\t\t\t0.713 | \n\t\t\t6 | \n\t\t
Cannot find manure for purchase | \n\t\t\t1.92 | \n\t\t\t0.778 | \n\t\t\t18 | \n\t\t\t2.56 | \n\t\t\t0.66 | \n\t\t\t7 | \n\t\t\t2.2 | \n\t\t\t0.645 | \n\t\t\t8 | \n\t\t
Cannot find labour to hire | \n\t\t\t1.73 | \n\t\t\t0.764 | \n\t\t\t20 | \n\t\t\t1.76 | \n\t\t\t0.816 | \n\t\t\t20 | \n\t\t\t2 | \n\t\t\t0.764 | \n\t\t\t13 | \n\t\t
Cannot access more cop land | \n\t\t\t1.95 | \n\t\t\t0.753 | \n\t\t\t16 | \n\t\t\t1.98 | \n\t\t\t0.805 | \n\t\t\t19 | \n\t\t\t1.92 | \n\t\t\t0.794 | \n\t\t\t14 | \n\t\t
Delay of payment of products sent to pack house | \n\t\t\t2.22 | \n\t\t\t0.723 | \n\t\t\t12 | \n\t\t\t2.89 | \n\t\t\t0.315 | \n\t\t\t1 | \n\t\t\t- | \n\t\t\t- | \n\t\t\t- | \n\t\t
Lack of bargaining power over product prices at the pack house | \n\t\t\t2.16 | \n\t\t\t0.672 | \n\t\t\t14 | \n\t\t\t2.2 | \n\t\t\t0.704 | \n\t\t\t14 | \n\t\t\t- | \n\t\t\t- | \n\t\t\t- | \n\t\t
Lack of information about consumer preferences for organic products | \n\t\t\t2.23 | \n\t\t\t0.654 | \n\t\t\t11 | \n\t\t\t2.44 | \n\t\t\t0.604 | \n\t\t\t10 | \n\t\t\t- | \n\t\t\t- | \n\t\t\t- | \n\t\t
No reward system or incentive for smallholder producers | \n\t\t\t1.86 | \n\t\t\t0.78 | \n\t\t\t19 | \n\t\t\t2.02 | \n\t\t\t0.866 | \n\t\t\t17 | \n\t\t\t- | \n\t\t\t- | \n\t\t\t- | \n\t\t
\n\t\t\t | \n\t\t\t | \n\t\t\t | \n\t\t\t | \n\t\t\t | \n\t\t\t | \n\t\t\t | \n\t\t\t | \n\t\t\t | \n\t\t |
Identification and ranking of risk sources by farmers
The most important traditional risk management strategies used by the farmers were identified as crop diversification, precautionary savings and participating in social network. The overall Herfindahl index of crop diversification is estimated at 0. 61 which indicates that the cropping system is relatively diverse (Table 6). These results confirm previous findings by [43] who obtained an estimated DHI of 0. 49-0. 69 among smallholder farmers in three regions in Bangladesh. As shown in Table 6, non-organic farmers practiced more crop diversification with a DH index of 0. 23 compared to organic farmers with a DHI of 0. 72. These results are consistent with previous findings in this study measuring farmers risk attitudes and presented in Figure 6. 8, that established that smallholder farmers in the study area tend to diversify due to their risk averse nature and that non-organic farmers are more risk averse than organic farmers.
According to Table 6, a total of 69. 1% of fully-certified farmers practised crop diversification compared to 96. 8% of the non-organic farmers. A total of 81. 2% of the partially certified farmers practised crop diversification. The common crops grown by the organic farmers are amadumbe, potatoes, sweet potatoes and green beans while non-organic farmers grew amadumbe, potatoes, sweet potatoes, green beans, maize, sugarcane, bananas, chillies and peas.
\n\t\t\t | \n\t\t\t | |||
1 | \n\t\t\tEnterprise diversification index (DH) | \n\t\t\t0.72 | \n\t\t\t0.89 | \n\t\t\t0.23 | \n\t\t
2 | \n\t\t\tPractice crop diversification (% of respondents) | \n\t\t\t69.10 | \n\t\t\t81.20 | \n\t\t\t96.80 | \n\t\t
3 | \n\t\t\tSavings bank account (% of respondents) | \n\t\t\t60.90 | \n\t\t\t48.90 | \n\t\t\t46.80 | \n\t\t
4 | \n\t\t\tCurrent level of savings (% of respondents) | \n\t\t\t\n\t\t\t | \n\t\t\t | \n\t\t |
\n\t\t\t | less than R500 | \n\t\t\t27.27 | \n\t\t\t37.84 | \n\t\t\t35.29 | \n\t\t
\n\t\t\t | R501 – R1000 | \n\t\t\t45.45 | \n\t\t\t29.73 | \n\t\t\t41.18 | \n\t\t
\n\t\t\t | R1001 – R5000 | \n\t\t\t21.21 | \n\t\t\t29.73 | \n\t\t\t17.65 | \n\t\t
\n\t\t\t | More than 5000 | \n\t\t\t6.07 | \n\t\t\t2.70 | \n\t\t\t5.88 | \n\t\t
5 | \n\t\t\tSocial networks (% of respondents) | \n\t\t\t\n\t\t\t | \n\t\t\t | \n\t\t |
\n\t\t\t | Membership of EFO | \n\t\t\t100.00 | \n\t\t\t100.00 | \n\t\t\t10.00 | \n\t\t
\n\t\t\t | Others (burial clubs, | \n\t\t\t33.00 | \n\t\t\t25.00 | \n\t\t\t25.00 | \n\t\t
\n\t\t\t | \n\t\t\t | \n\t\t\t | \n\t\t\t | \n\t\t |
Risk management strategies used by the different farmer groups
Precautionary saving occurs in response to risk and uncertainty [44]. The smallholder farmers’ precautionary motive was to delay/minimise consumption and save in the current period due to their lack of crop insurance markets. According to [45], the quantitative significance of precautionary saving depends on how much risk consumers face. Whereas 60. 9% of the fully certified farmers had savings bank accounts, only 46. 8% non-organic farmers had bank accounts. The current level of saving in the study area was low with savings ranging from less than R500 to over R5000 per month. The level of savings was low across all groups. Among the fully-certified organic group, most of the respondents (45. 45%) saved between R1000-R5001 whereas most of the partially-certified farmers (37. 84%) saved less than R500 per month. Most of the non-organic farmers (41. 18%) saved between R501-R1000 per month. Across all groups, however the level of saving greater than R5000 was minimal.
The farmers also engage in social networks as a risk sharing strategy. There were two main categories of social networks that the farmers engaged in. These are farmers association and other social networks most notably burial clubs and stockvels. The farmers association is used as a vehicle by the organic farmers to gain access to markets for their organic produce while the burial clubs and stockvels are sources of access to credit and/or loans. In the latter instance, farmers do not have to produce collateral. The burial clubs and stockvels are common in most rural areas and are a source of mitigating liquidity and financial risk where possible.
The summary statistics of consumers presented in Table 7 showed that the majority of the consumers were females within 25-34 age category. Previous studies for example [46] found that women were the predominant purchasers of organic food and responsible for household consumption. The younger generation consumers represent an important target group in the advancement of consumer demand for organic products. The level of education was generally low especially among rural consumers. The unemployment rates in the former homelands demonstrates a substantial skewering of the demographic profile of the district and high dependency rates of those not economically and productively active. It also reflects the levels of out migration of economically active population from the province to other parts of South Africa. Unemployment was also lower in urban areas than rural areas. The income distribution of the respondents is especially concentrated in the R1000 – R5000/month category. However the majority of the respondents within this category were in the rural areas. This can be attributed to limited economic activity in rural areas. The household size was within the provincial estimate of 4-5 persons per household [47] with rural households having higher numbers. Majority of the respondents had children under the age of 18 years in the household. The average distance to the nearest shops were estimated at between 6-9kms. In the urban areas however this was reduced to 1. 38kms.
\n\t\t\t | \n\t\t\t\t | \n\t\t\t\n\t\t\t\t | \n\t\t\t\n\t\t\t\t | \n\t\t|||
\n\t\t\t | \n\t\t\t | \n\t\t\t\t | \n\t\t\t\n\t\t\t\t | \n\t\t\t\n\t\t\t\t | \n\t\t\t\n\t\t\t\t | \n\t\t\t\n\t\t\t\t | \n\t\t
\n\t\t\t\t | \n\t\t\t\n\t\t\t\t | \n\t\t\t|||||
\n\t\t\t | \n\t\t\t | \n\t\t\t | \n\t\t\t | \n\t\t\t | \n\t\t\t | \n\t\t |
\n\t\t\t\t | \n\t\t\tMale | \n\t\t\t43 | \n\t\t\t34 | \n\t\t\t28 | \n\t\t\t40 | \n\t\t\t44 | \n\t\t
Female | \n\t\t\t57 | \n\t\t\t66 | \n\t\t\t72 | \n\t\t\t60 | \n\t\t\t56 | \n\t\t|
\n\t\t\t\t | \n\t\t\t18-24 | \n\t\t\t17 | \n\t\t\t13 | \n\t\t\t18 | \n\t\t\t16 | \n\t\t\t12 | \n\t\t
25-34 | \n\t\t\t29 | \n\t\t\t33 | \n\t\t\t12 | \n\t\t\t34 | \n\t\t\t26 | \n\t\t|
35-44 | \n\t\t\t27 | \n\t\t\t16 | \n\t\t\t14 | \n\t\t\t23 | \n\t\t\t41 | \n\t\t|
45-55 | \n\t\t\t20 | \n\t\t\t17 | \n\t\t\t21 | \n\t\t\t19 | \n\t\t\t16 | \n\t\t|
>55 | \n\t7 | \n\t21 | \n\t35 | \n\t8 | \n\t5 | \n|
\n\t\t | \n\tNone | \n\t4 | \n\t9.7 | \n\t16.1 | \n\t6.5 | \n\t1.2 | \n
Primary | \n\t21 | \n\t29.1 | \n\t46.4 | \n\t32.3 | \n\t5.9 | \n|
High school | \n\t39 | \n\t39.8 | \n\t37.5 | \n\t48.4 | \n\t34.1 | \n|
Tertiary | \n\t36 | \n\t21.4 | \n\t0 | \n\t12.9 | \n\t58.8 | \n|
\n\t\t | \n\tUnemployed | \n\t29.4 | \n\t31 | \n\t52.6 | \n\t48.3 | \n\t2.4 | \n
Student | \n\t9.8 | \n\t4 | \n\t5.3 | \n\t5 | \n\t9.4 | \n|
Housewife/man | \n\t10.8 | \n\t8 | \n\t19.3 | \n\t10 | \n\t2.4 | \n|
Retired | \n\t5.9 | \n\t1 | \n\t8.8 | \n\t1.7 | \n\t1.2 | \n|
Working part-time | \n\t14.7 | \n\t11 | \n\t8.7 | \n\t18.3 | \n\t11.8 | \n|
Working full time | \n\t29.4 | \n\t45 | \n\t5.3 | \n\t16.7 | \n\t72.8 | \n|
\n\t\t | \n\t<1000 | \n\t10 | \n\t12.5 | \n\t0 | \n\t4.8 | \n\t23.5 | \n
1001 – 5000 | \n\t16 | \n\t5.8 | \n\t0 | \n\t0 | \n\t25.9 | \n|
5001-10 000 | \n\t20 | \n\t17.3 | \n\t5.3 | \n\t17.7 | \n\t28.2 | \n|
10 001 – 15 000 | \n\t30 | \n\t49 | \n\t66.7 | \n\t46.8 | \n\t16.5 | \n|
>15 000 | \n24 | \n15.4 | \n28.1 | \n30.6 | \n5.9 | \n|
\n\t\t | \n\t5.2 | \n\t4.33 | \n\t5.18 | \n\t4.98 | \n\t4.31 | \n|
\n\t\t | \n\t79 | \n\t55.8 | \n\t71.9 | \n\t71 | \n\t61.2 | \n|
\n\t\t | \n\t6.71 | \n\t9.63 | \n\t12.67 | \n\t9.32 | \n\t1.38 | \n
Summary statistics of consumers in the Eastern Cape Province
There is a general understanding of term ‘organic foods’ among consumers. Consumers defined organic foods as healthy and nutritious, associated with traditional and or indigenous methods of production and free from chemicals. There were low levels of awareness about local standards for organic products, the identification of organic products using an organic logo, existence of a national organic movement and/or the presence of an organic certification body in South Africa. Therefore consumers could not readily identify certified organic against non-certified organic products. Notwithstanding, consumers argued that there was a need for certification and verification of organic products and hence are unable to make informed decisions on the organic status of products in the market.
Trust of organic labels can be increased once more information is available to consumers on the various organic labels, their meaning and on the difference between certified and non certified products in the shelves. In the absence of this information, producers and likewise consumers may not get value for money. Certification and labelling is essentially in regulating and facilitating the sale of organic products to consumers. The perception of the high price of organic products is a deterrent to the purchase of organic products and hence the growth of organic industry especially for the emerging organic market of South Africa. To increase the consumption of organic products, it will be important to motivate new consumer segments to buy organic food. Hence trust is a crucial aspect when consumers decide whether to buy or not to buy organic products [48].
Trust is a ‘credence attribute’ which is not directly observable by consumers. Enhancing consumers trust about the labels of organic products can be achieved through among others, effective communication strategies on the traceability of organic products and ensuring compliance and adherence by retailers selling organic products to the certification standards and availability of information on the organic status of products. Some of the reasons advanced in the study to increase consumers trust for organic products is to:
purchase from specific shops that sell organic
check for organic certification label
practice own organic farming
In South Africa, food retailers have the largest share of the organic industry [49]. Similarly, most products are sold through the export market due to the higher revenue from exports. Irwin [50] says that South Africa has a favourable position for expansion in the domestic market as a result of the following developments in the organic sector over the past few years:
establishment of separate organic section in major retail stores
national regulation/standards for organic products
establishment of South Africa organic certification bodies
formation of South African organic associations.
Food purchasing is an important part of food behaviours. In this study the apportioning, explicitly or tacitly, of the responsibility of household food shopping depends on a number of factors as food purchasing is an important part of food behaviours. This responsibility was closely shared among various members of the household with majority of the consumers being responsible for the decision making of organic food demand and purchase. The general finding in the study was that most consumers shop in supermarkets, grocery stores and
Commonly consumed organic products included fresh vegetables, fresh fruits, meat/meat products and milk/ milk products. However, the general trend in Figure 5 and Figure 6 shows that there are marked increases in the future demand of all organic products. This augurs well for the growth of the organic industry in the Eastern Cape and in South Africa in General. The findings of this study are consistent with [52] who stated that a study by Pick-n-Pay, one of the major national retail supermarket chains and supporter of the development of the retail organic market in South Africa, on the performance and trends of fresh organic produce showed that fresh produce completely dominated the sales.
Demand difference between organic products today and in the future in OR Tambo District Municipality
Demand difference between organic products today and in the future in Amatole District Municipality
This is an indication that the consumption of organic products is closely related to consumer awareness and knowledge of organic products. Increasing awareness about organic products to consumers is important to spur its demand. Most of the consumers had consumed organic products in South Africa with non consumers showing a general interest in organic products. Authors [53] state that consumer awareness of organic foods is the first step in developing demand for organic products. Yet, awareness does not necessarily equate with consumption. While organic refers to the way agricultural products are grown and processed [54], interest in consuming organic products may relate to food safety concerns where organic products may be a partial answer to recent food scares associated with production and handling (e. g. BSE, dioxins, Salmonella, etc. ). Food safety issues have driven consumers to search for safer foods whose qualities and attributes are guaranteed [55]. The main reasons advanced for the consumption of organic products are that organics are healthy and nutritious, have a better appearance and taste, are affordable and are safe to consume. Identified hindrances to the consumption of organics are that they are expensive and not readily available. Price and affordability of organic products was ranked as the most important consideration among all consumers when buying organic products in South Africa.
The global markets for organic products have grown rapidly over the past two decades [8]. Currently 32. 2 million ha are being managed organically worldwide by more than 1. 2 million producers [11]. In Africa, South Africa has the third largest area (50, 000ha) under organic farming [11]. Organic production is particularly well-suited for smallholder farmers, who comprise the majority of the world\'s poor. The promotion of organic agriculture does not only constitute an important option for producersbut also responds to consumers’ desire for higher food quality and food production methods that are less damaging to the environment. The consumers’ concerns for food safety, quality and nutrition are increasingly becoming important across the world, which has provided growing opportunities for organic foods in recent years. Expectedly, the demand for organic food is steadily increasing in the developing countries. The untapped potential markets for organic foods in the countries like South Africa need to be realised with organised interventions on various fronts, which require a better understanding of the consumers’ preference for organic food. Therefore, an analysis of consumer’s awareness of various aspects of organic products may be considered as important ground to build the markets for organic food in the initial phase of market development. Recent analysis [53] indicate that consumer awareness of organic foods is the first step in developing demand for organic products. By identifying independent variables that explain the adoption of organic farming, the present study sought to contribute to policy formulation to promote adoption in South Africa and the rest of Africa. The identified sources of risk faced by smallholder farmers provide useful insights for policy makers, advisers, developers and sellers of risk management strategies. This information can yield substantial payouts in terms of the development of quality farm management and education programs as well as the design of more effective government policies.
Insertion of intercostal drainage (ICD) tube is a common procedure that is required to drain the abnormal intrapleural collection. As the name implies, it is insertion of a tube through the intercostal space to facilitate the drainage of abnormal collection in the pleural cavity. The procedure is also known as tube thoracostomy and thoracostomy drainage. The earliest reports of thoracic drainage dates back to 5th century BC [1, 2].
The aim of thoracostomy drainage is to:
Remove fluid and air from pleural cavity as promptly as possible.
Prevent drained air and fluid from returning to pleural cavity.
Restore negative pressure in pleural cavity to help re-expand the lung.
Although, the procedure has been in practice since long, there is still no consensus in the management of chest tubes and there remains great variability in practice. The procedure of inserting a chest tube is simple, definitive in treating a majority of thoracic pathologies and may be life-saving in certain situations. However, improperly placed chest tubes and poor post-procedural care may increase the morbidity and is associated with complications in up to 40% of patients [3, 4]. It is therefore imperative that all clinicians should be well versed with this simple yet life-saving procedure.
In this chapter, we will discuss various aspects of intercostal drainage including the prerequisites, technique of insertion, post-procedural care, complications and common pitfalls in the management of chest tubes in the light of the recent advances and updates.
An ideal thoracostomy tube should:
Allow collected air and fluid to drain out from the chest.
Contain a one-way valve to prevent air and fluid from returning back into the chest.
Allow maintenance of negative intra-pleural pressure (the normal intrapleural pressure is −3 mmHg that decreases further on inspiration).
Have provision for applying higher negative pressure to help in expanding the lung.
Allow accurate measurement of drained fluid and air.
Tube thoracostomy is required to drain any abnormal collection in the pleural cavity, that includes:
Air: Pneumothorax
Fluid: Pleural effusion
Blood: Hemothorax
Pus: Empyema
Chyle: Chylothorax
Prophylactically following cardio-thoracic surgery to drain post-operative collection of air, fluid or blood
The modern, commercially available chest tubes are soft and pliable that are either made up of Polyvinyl chloride (PVC) or silicone (Figure 1).
Intercostal drainage tube (chest tube).
The red rubber or malecot tube drains (Figure 2) are sometimes used as thoracostomy tubes mostly in resource constraint settings because of their low-cost, however their use is not advisable as they are difficult to retain, get kinked easily, wither rapidly and at times may break.
Malecot (red rubber) tube drain.
Chest tubes come in various sizes from 6 French gauge (F) to 40 F. Larger the size of the tube, greater is its diameter. One F is equal to 0.033 cm. To know the diameter of the tube from the F size, one need to multiply F size by a factor of 0.033, so a chest tube of size 24 F will have an internal diameter of approximately 0.8 cm.
Some chest tubes are available with metallic trocar that has a pointed end (Figure 3).
Chest tube with metallic trocar.
These are meant to insert in intercostal space after making a small skin incision, without dissecting the intercostal muscles. Although, this makes the procedure fast, there is a higher risk of injury to the intrathoracic organs and as such use of chest tubes with trocars should be discouraged [3, 5, 6]. Most of the chest tubes are open from one end while the other end is sealed. There are side holes or eyes on the tube and the markings are printed on it. There also is a radiopaque line all along the length of the tube that helps in identifying the position of the chest tube on X-ray (Figures 1 and 4).
Radiopaque line in the chest tube visible on x-ray (arrow).
Insertion of ICD tube is a surgical procedure and like any other surgery, a written informed consent is required prior to the procedure. Consent may not be possible in cases where the patient requires urgent tube thoracostomy as a lifesaving measure and when he/ she is unconscious, unattended or is in extremis.
Following instruments and equipment are required for inserting the chest tube. One must ensure the availability of all necessary equipment beforehand to avoid any difficulty during the procedure.
5 ml syringe with a suitable local anesthetic. Preferably 2% lidocaine with adrenaline.
Sponge holding forceps
Bowl with solution for painting
Number 11 surgical blade with handle
Sheets for draping
A pair of medium sized curved artery forceps
An appropriately sized chest tube: See the section on ‘selecting the size of chest tube.
Silk No.1 suture on cutting needle
Needle holder
A pair of tooth forceps
Prepared underwater seal bottle or bag.
Gauze pieces
Adhesive tape for dressing
The chest tubes are available in various sizes ranging from 6 F to 40 F. There is a general understanding that large-bore tubes are required to drain fluid and small-bore tubes are sufficient to drain air. There have been numerous studies on this issue, however there is no conclusive scientific data to support this idea. Large-bore tubes have been related to higher incidence of pain and patient discomfort without any significant advantage in draining the intra-pleural fluid. In various studies, small-bore tubes have been found to be equally effective to drain pleural effusion and hemothorax [7, 8, 9, 10, 11]. This has generated wider interest in use of small-bore tubes for thoracostomy. Conventionally, for most of the clinical conditions requiring tube thoracostomy a 24–32 F chest tube is inserted, depending on the expected underlying pathology, however tubes smaller than 24 F may be sufficient to drain pneumothorax.
The reservoirs for collecting the pleural drainage are available either in the form of bags or single or multiple chambered plastic bottles (Figure 5A and B).
A: Two chambered plastic bottle and B: ICD bag.
In both of these reservoirs, there are markings for calculation of effluent. In addition, there is also a marking for ‘initial fluid level’. Before connecting the reservoir to the chest tube, a sterile fluid like normal saline should be filled till this mark. As the chest tube is connected with the tube in the reservoir that remains below the ‘initial fluid level’, the air from the environment cannot gain access to the pleural cavity, however the intrapleural collection may egress easily into the reservoir, thus it functions as a one-way valve or ‘under water seal’.
Any suitable local anesthetic is appropriate for the procedure. Plain Lidocaine 2% solution and Lidocaine 2% with adrenaline are commonly used drugs for ICD insertion. A volume of nearly 5 ml is sufficient to anesthetize the local site. Local anesthesia may not be required where the patient is obtunded or unconscious and ICD insertion is required urgently.
The step by step procedure is demonstrated in the video supplemented with this article.
Inserting Intercostal drainage tube: step by step.
Although the ICD can be inserted while the patient is sitting, leaning forward with the forearms resting over a stool, the supine position is less cumbersome and more comfortable for both patient and the doctor. In addition, the patient may not be able to sit for the procedure due to the underlying clinical condition. We prefer to insert ICD tube in supine position. The patient lies on the table close to the edge with arm abducted over the head if possible.
The ideal site of inserting ICD is 4th or 5th intercostal space just anterior to the mid axillary line. One may calculate the desired intercostal space by considering sternal angle as landmark. The rib attached to the level of sternal angle is the second rib, subsequent ribs can be counted while palpating the chest wall distally and laterally. There is an alternative way of counting the ribs and the intercostal spaces which is quick and is particularly helpful in obese patients and in presence of subcutaneous emphysema. The level of the nipple in males and inframammary crease in females can be taken as a reference point- a line drawn from this point laterally to a point where it intersects the mid-axillary line is marked and the site for insertion of the chest tube is just anterior to this.
In case, the chest tube is being inserted prophylactically during thoracic surgery, the site of insertion is selected under vision in appropriate intercostal space.
A wide area around the predetermined site of ICD insertion is painted with a suitable antimicrobial solution (Chlorhexidine or Povidone-iodine) and is draped. If the patient is awake and conscious, 5 ml of local anesthetic solution (preferably 2% lidocaine with adrenaline) is infiltrated in the overlying skin, intercostal muscles and pleura at the site of ICD insertion. Before injecting the local anesthetic, one should ensure that the needle is not in a blood vessel by pulling the plunger of the syringe back. For the adequate effect of local anesthesia, it is prudent to wait for at least 2 minutes before making the incision.
An incision measuring nearly 1.5–2 cms is made by a number 11 surgical blade at the predetermined site of ICD insertion along the long axis of the rib in the intercostal space just over the upper border of the lower rib. This is done to prevent injury to the neurovascular bundle that runs along the lower border of the ribs.
Using a medium sized curved hemostatic clamp, the subcutaneous tissues and inter-costal muscles are dissected bluntly till the parietal pleura is reached. By the tip of the closed hemostatic clamp, gentle pressure is then applied till there is a feeling of ‘give way’ which marks the entry into the pleural cavity. The entry into the pleural cavity is also confirmed by the escape of intra-pleural collection like air, fluid or blood (as the case may be). One should be careful enough not to apply undue force while puncturing the pleura as this may cause injury to lungs or mediastinal structures. The jaws of the hemostatic clamp are then opened while withdrawing the instrument to increase the size of the thoracostomy wide enough to allow the entry of index finger. This should be followed by ‘finger thoracostomy’. The index finger is inserted through the thoracostomy site to explore the pleural cavity for presence of any pleuro-pulmonary adhesions. In case they are present, adhesiolysis is performed to create space inside the pleural cavity for the chest tube. This step is important as attempts to insert a chest tube without ensuring space between the lung and the chest wall may injure the lung, cause air leak from the damaged lung parenchyma and such improperly placed tube may fail to drain the intra-pleural collection.
Following finger thoracostomy and ensuring safe space inside the pleural cavity to accommodate the chest tube, an adequately sized chest tube is then taken. The tip of the tube from the open end (the end that should lie inside the thoracic cavity) is held with the tip of the hemostatic clamp and the rest of the tube is held parallel to the instrument. The tube is introduced inside the pleural cavity, the instrument is then released and the tube is inserted gradually by guiding it to lie posteriorly and superiorly by using the same instrument aided by the index finger of the opposite hand to the point till the last eye (hole) on the chest tube is at least 5 cms inside the pleural cavity (this can be confirmed by looking at the markings over the chest tube). The limit to which the ICD tube needs to be put in depends on the build of the patient. In a patient with an average built a length till 8–12 cms inside the chest is sufficient.
The tube is then clamped by using an artery forceps (hemostatic clamp) close to its distal (closed) end. The end of the chest tube is now cut and is connected with the tubing of the underwater seal using the connector provided with the chest tube. The length of the tube of under-water seal apparatus should not be unduly long as the fluid column in the tube will provide resistance to the egress of intrapleural collection compromising the drainage. A good rule is not to allow any loop in the draining tube between the connector and the tubing of the reservoir.
The chest tube is then fixed by silk suture no.1. For better fixity, it should be anchored on either side. While fixing, one must ensure to take deep bites through the soft tissues close to the tube. Fixing the tube by taking superficial bites (including skin only) may leave potential space around the tube at the site of entry in the intercostal space which may lead to subcutaneous emphysema in cases of pneumothorax and may increase morbidity. Some clinicians prefer purse string suture for fixation of the tube but that leaves an ugly scar following removal of the chest tube and as such is not necessary. A dressing is now applied at the ICD site and the tube may then firmly be reinforced at the site by using adhesive tapes. This completes the procedure.
The free drainage of the collected material from the pleural cavity and the movement of the column of the fluid in the tube confirms the adequate position of the chest tube. The chest should now be auscultated, improvement in the breath sounds suggests success of the procedure. A chest X-ray is then performed for confirmation of proper positioning of the tube radiologically.
Some authors advocate creation of an oblique passage or ‘tunnel’ in the chest wall to insert the tube, primarily to decrease the incidence of recurrent pneumothorax following removal of the chest tube [12]. In this technique incision is made one intercostal space below the pre-determined site of thoracostomy, the skin and soft tissues of the chest wall are then bluntly dissected to reach the site of thoracostomy thereby creating a curved passage through the chest wall for introduction of the chest tube. This requires additional time at the expense of no added advantage and therefore is not required.
Utmost care should be exercised while nursing a patient with chest tube. The reservoir should remain below the level of the chest at all times. Raising the reservoir above the chest level may result in passage of the fluid from the reservoir back into the pleural cavity. While turning or shifting the patient, one must ensure that the tube is not held or entangled in the patient’s bed. This may result in accidental displacement or dismantling of the tube. The outlet of the reservoir should remain open at all times especially in patients with pneumothorax or air leak. The closed outlet of the reservoir may lead to failure of decompression of pneumothorax leading to development of life-threatening tension pneumothorax. For the same reason, the tube should not be clamped at any time except while changing the fluid in the reservoir, collecting a sample of effluent or while planning to remove the chest tube. The patient should be closely monitored during this period.
The patient should be motivated for active physiotherapy and incentive spirometry (Figure 6).
Patient performing incentive spirometry.
This aids in faster resolution of pleural collection and thereby early removal of the ICD tube. In case, the patient is unable to do active physiotherapy, passive physiotherapy should be performed. All efforts must be made to ambulate the patient early. The chest tube must be secured carefully while patient mobilizes and the drainage bag (reservoir) should be kept well below the thoracostomy site.
The ICD site should be carefully examined every day for signs of local infection like peri-tubal inflammation or tenderness. The dressing needs to be changed in case it is soaked. Extreme care must be taken while dressing the ICD site lest the tube is displaced or dismantled. The patient should be clinically monitored every day and the volume of drained fluid should be charted carefully in the patient’s record. The reservoir should be emptied once it is full up to 3/4 of its capacity. A new reservoir with prepared under water seal or disposable reservoir (in case of digital chest tube drainage systems) is kept ready while changing the reservoir. In resource constraint settings the same reservoir may be reused. It is important to follow universal precautions while changing the reservoir. The chest tube is clamped and the filled reservoir is disconnected from the tube, the new reservoir is then connected or fluid is filled up to the ‘initial water level’ mark (or till the outlet tube is at least 2 cms below the water level) in case one contemplates to use the same reservoir. Once the reservoir is reattached, the tube is unclamped. It is important to prepare the equipment beforehand while changing the reservoir to keep the time of occlusion of the chest tube to minimum possible.
The practice of performing daily x-ray has been questioned by many authors and it is suggested that this may not be required if there is pleura to pleura apposition in the post-procedure x-ray and the patient is improving clinically [13].
Appropriate oral or parenteral analgesics are administered depending on the underlying condition for which tube thoracostomy was necessitated. There has been much debate on the use of antibiotics following tube thoracostomy. There is no evidence to support the routine use of prophylactic antibiotic therapy following the procedure [14, 15]. However, the antibiotics may be needed for other associated causes for which tube thoracostomy was performed like in empyema thoracis or in a patient of trauma with soft tissue injuries.
The use of controlled suction (−10 to −15 cm saline) to the outlet of the reservoir may help in faster resolution of intrapleural collection and promote early pleura to pleura approximation. This is most useful following pulmonary resections and may decrease the incidence of persistent post-operative space problems. In our practice, we apply overnight suction in patients undergoing pulmonary resection surgery (except following pneumonectomy). At times, the application of suction may result in pleural pain, the amount of suction should be decreased in such situations. In case of increased air leak on application of suction, the suction may be decreased or avoided altogether.
Blockage of thoracostomy tube is not uncommon and occur frequently in hemothorax. Careful observation of the ICD tube and the ensuring drainage of the fluid are paramount to detect this complication early. If appropriate measures are taken in time, the possibility of maintaining the tube patency are high.
Various manipulations can be performed to restore the patency of blocked ICD tube. These include tapping, milking and stripping of the tube. These measures are successful only with partial blockage of the tube and should not be performed routinely to prevent blockage. There is theoretical possibility of generation of high intrapleural pressures with stripping and milking. Some authors have raised concern that this may cause pulmonary injury, however we have not observed any clinically significant adverse effects of these procedures. The practice of flushing the blocked tube by instilling sterile solutions should be discouraged as this may increase the chances of introducing infection from outside with resultant increase in the incidence of empyema. Some clinicians have used novel methods like using a fogarty balloon catheter to unblock the chest tube [16] or use of advanced systems to either prevent clot formation inside the tube [17] or wipe the inside of tube to unblock it [18].
A loop is formed in the ICD tube and the intrapleural fluid is allowed to accumulate in this loop. The tube is then clamped proximal to this collected fluid. With all aseptic measures the external surface of the ICD tube near its connection with the tubing of the reservoir is cleaned with alcohol based antiseptic solution. The tube is then disconnected from this end and the sample is collected in a sterile container. The ICD tube is then reconnected with the reservoir tube and is unclamped.
There are no fixed or universally agreed criteria that applies to all patients for guiding removal of the thoracostomy tube. There is great heterogeneity in practice, however the rule of thumb is that the chest tube should be removed once it has served its purpose. If the patient is clinically well, there is no more air leak than on forced expiration, no expanding subcutaneous emphysema, no blood, pus or chyle in the effluent and the volume of the fluid being drained is less than 250 ml, the tube can be safely removed. In case of residual space following pulmonary resection with persistent low volume air leak (no more than on forced expiration) beyond day 5, the chest tube may be clamped for up to 24 hours and a repeat x-ray is performed. The patient should be closely monitored during this period for tachypnoea or dyspnea. In case the patient remains asymptomatic and the pneumothorax does not worsen, the chest tube may be removed. The same may be done in case of persistent non-expanding effusion. This practice however, carries the risk of serious side effects if the patient monitoring following clamping of the tube is not diligent. The use of digital chest tube drainage devices might obviate this risk. The chest tube may be safely removed if the air leak is <40 ml/ min over 24 hours [19]. Alternatively, in patients with prolonged air leak (beyond day 5), a Heimlich valve may be applied to the chest tube and the patient may be followed on outpatient basis with a plan to remove the tube later allowing more opportunity for the residual lung to expand. We have recently proposed a protocol for removal of chest tubes following thoracic surgery that have enabled us to decrease the chest tube indwelling time [20].
In some specialties like Colorectal and Gynecological Surgery, the Enhanced Recovery After Surgery (ERAS) protocol has been well established. This has recently been proposed for patients undergoing oncological major lung resection surgery too. The guidelines suggest that chest tubes may safely be removed with a non-chylous fluid output of up to 450 ml/ day in absence of air leak or minimal air leak detected by the digital chest tube drainage systems [21].
The view is equally divided regarding removal of the chest tube during end-inspiration or end-expiration [22, 23]. In a Randomized Controlled Trial by Bell RL et al., there was no significant difference between the complications following removal of the chest tube at either the height of inspiration or expiration and both methods were considered safe [23]. The incidence of recurrent pneumothorax is likely to be multifactorial and correlates poorly to the method of chest tube removal alone [23, 24]. We prefer to remove the chest tube by a swift motion followed immediately by sealing of the thoracostomy wound by appropriate dressing material irrespective of the phase of respiration.
The complications of tube thoracostomy may be divided into 3 phases:
During insertion of the tube:
Hemorrhage from the ICD site
Injury to the lung and the mediastinal structures
Misplacement of the tube
During the indwelling time of the chest tube:
Displacement or dislodgement of the tube
Subcutaneous emphysema
Kinking
Blockage
Fracture of the tube
Empyema thoracis
Wound infection
Re-expansion pulmonary edema
Following removal of the tube
Recurrent pneumothorax or pleural effusion
Thoracostomy site pain
Hemorrhage from the ICD site may be avoided by carefully siting the thoracostomy incision on the upper border of the lower rib in the desired intercostal space. This avoids the damage to the neurovascular bundle that runs along the lower border of the rib. All aseptic measures should be taken while inserting the chest tube and later while handling the tube during the post procedural care to prevent wound infection and empyema. Care should be exercised while nursing and mobilizing the patient with chest tube to prevent accidental displacement or dislodgement of the tube.
To prevent re-expansion pulmonary edema, the pleural cavity should be gradually decompressed. Sudden evacuation of more than one liter of fluid from the thoracic cavity should be avoided. It is desirable to monitor the intrapleural pressure while draining large amount of fluid from the pleural cavity. The intrapleural pressure should not be allowed to fall below −20 cm saline at any point of time.
A pitfall is different from complication and is defined as a hidden or unsuspected danger or difficulty that may lead to adverse events. The awareness of a pitfall and preparation to act swiftly in such eventuality may help in averting the complication arising from it. Following are the common pitfalls in ICD tube management:
Missed diagnosis: ICD tube placed in a patient with large diaphragmatic hernia suspecting it to be a loculated pneumothorax. A careful history and diligent look at the x-ray will avoid this pitfall (Figure 7A and B).
Placement of ICD on wrong side: One should confirm the side with pathology before putting the chest tube. The history of the patient, clinical notes and the radiological findings should be correlated to correctly identify the side of pathology.
A large thoracostomy incision may result in potential space around the chest tube. This coupled with fixation of the tube by superficial skin suturing results in development of a closed plane in the subcutaneous tissues. Peri-tubal air leak in this situation may lead to massive surgical emphysema with attended morbidity and mortality.
Avoiding digital exploration of the pleural cavity may result in injury to pulmonary parenchyma in addition to improper positioning and kinking of the tube (Figure 8).
One must perform ‘finger thoracostomy’ before inserting the chest tube to avoid this from happening.
Use of tubes with trocar and applying undue force while gaining entry to the pleural cavity may result in injury to various thoracic, mediastinal or intra-abdominal organs.
Poor placement result in a tube that may be:
Too in: may impinge on to the mediastinal structures (Figure 9A and B).
Too out: the eye (hole) of the tube may lie in the subcutaneous tissues with resultant subcutaneous emphysema (Figure 10).
Mispositioned or kinked resulting in poor drainage (Figures 11–14).
Poor fixation of the chest tube may result in accidental displacement or dislodgement (Figure 11). The chest tube should be anchored properly with number 1 silk suture. An additional suture from the opposite side improves the fixation and decreases the chances of this mishap.
Improper filling of the reservoir (under water seal) with sterile solution so that the outlet tube is not beneath the water column may result in pneumothorax.
Raising the reservoir above the level of the chest may result in drainage of the collected material back into the thoracic cavity. The reservoir should remain below the chest level of the patient at all times.
Clamping the tube while shifting or mobilizing the patient may result in tension pneumothorax. The outlet of the reservoir should be kept open at all times to prevent this.
A: Left sided diaphragmatic hernia with large gastric shadow. B: Chest tube inserted in a patient of diaphragmatic hernia misdiagnosed as hydropneumothorax.
A kinked chest tube.
A & B: Chest tube impinging on mediastinal structures.
Eye of chest tube in subcutaneous tissues with subcutaneous emphysema.
Chest tube (arrow) about to come out.
Chest tube lying outside the chest wall.
Mispositioned tube over the diaphragm (arrow).
Mispositioned tube lying in abdomen (arrow).
With the advancement in technology, newer equipment has become available that may help in decreasing some of the complications associated with the tube thoracostomy, make the assessment of drainage more objective and accurate thus helping in better management of ICD tubes. Some of the advancement in the recent times are:
Devices for better fixation of the chest tubes: Some devices are available that claim better fixation of the chest tubes [25], others have been tested on animal models and may soon become available [26].
Digital chest tube drainage systems: This has been perhaps the most significant advancement that is now the part of most modern thoracic surgery units (Figure 15).
A patient being managed on digital chest tube drainage system following thoracotomy.
The use of these drainage systems has been associated with improved decision-making regarding chest tube management, decrease complications, improved quality of life and reduce the hospital stay [27, 28, 29] These are light weight, portable system with a disposable reservoir that may be replaced once full. The main advantages of this system are:
It does not require an ‘underwater seal’ thus eliminating the risk of accidental pneumothorax and passage of drained material from the reservoir back to the chest.
It allows accurate measurement of drained fluid and air over time and thus helps in assessment of the trend of drainage (Figure 16A & B).
A & B: Objective depiction of air and fluid drainage and trend of drainage in digital chest tube drainage system.
This may help the clinician in making decision for removal of chest tube more objective and accurately.
Continuous controlled suction may be applied to the chest tube that remains constant irrespective of the position of the drainage system.
The patient may easily carry the device while ambulation without the risk of changes in pressure effecting drainage or accidental drainage of the collected material back in chest.
Chest tube systems with inbuilt mechanism to keep the inside of the tube clean to prevent clogging [16, 18].
Motion activated systems for prevention of clot formation inside the chest tube: This system uses motion-activated energy (vibration) primarily to prevent early adhesion of clots within the internal chest tube surface and thus maintains the patency of the chest tube [17].
Insertion of ICD is a common, simple yet lifesaving procedure. All clinicians should be well versed with the appropriate technique of inserting the thoracostomy tube and various aspects of its management. Although simple, it is associated with high rate of complications that primarily occur due to improper technique of insertion or poor post-procedural care. Awareness of these factors will make the procedure safer with improved outcome.
There are no conflicts of interest.
"Open access contributes to scientific excellence and integrity. It opens up research results to wider analysis. It allows research results to be reused for new discoveries. And it enables the multi-disciplinary research that is needed to solve global 21st century problems. Open access connects science with society. It allows the public to engage with research. To go behind the headlines. And look at the scientific evidence. And it enables policy makers to draw on innovative solutions to societal challenges".
\n\nCarlos Moedas, the European Commissioner for Research Science and Innovation at the STM Annual Frankfurt Conference, October 2016.
",metaTitle:"About Open Access",metaDescription:"Open access contributes to scientific excellence and integrity. It opens up research results to wider analysis. It allows research results to be reused for new discoveries. And it enables the multi-disciplinary research that is needed to solve global 21st century problems. Open access connects science with society. It allows the public to engage with research. To go behind the headlines. And look at the scientific evidence. And it enables policy makers to draw on innovative solutions to societal challenges.\n\nCarlos Moedas, the European Commissioner for Research Science and Innovation at the STM Annual Frankfurt Conference, October 2016.",metaKeywords:null,canonicalURL:"about-open-access",contentRaw:'[{"type":"htmlEditorComponent","content":"The Open Access publishing movement started in the early 2000s when academic leaders from around the world participated in the formation of the Budapest Initiative. They developed recommendations for an Open Access publishing process, “which has worked for the past decade to provide the public with unrestricted, free access to scholarly research—much of which is publicly funded. Making the research publicly available to everyone—free of charge and without most copyright and licensing restrictions—will accelerate scientific research efforts and allow authors to reach a larger number of readers” (reference: http://www.budapestopenaccessinitiative.org)
\\n\\nIntechOpen’s co-founders, both scientists themselves, created the company while undertaking research in robotics at Vienna University. Their goal was to spread research freely “for scientists, by scientists’ to the rest of the world via the Open Access publishing model. The company soon became a signatory of the Budapest Initiative, which currently has more than 1000 supporting organizations worldwide, ranging from universities to funders.
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\\n\\nOA Publishing Fees
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The Open Access publishing movement started in the early 2000s when academic leaders from around the world participated in the formation of the Budapest Initiative. They developed recommendations for an Open Access publishing process, “which has worked for the past decade to provide the public with unrestricted, free access to scholarly research—much of which is publicly funded. Making the research publicly available to everyone—free of charge and without most copyright and licensing restrictions—will accelerate scientific research efforts and allow authors to reach a larger number of readers” (reference: http://www.budapestopenaccessinitiative.org)
\n\nIntechOpen’s co-founders, both scientists themselves, created the company while undertaking research in robotics at Vienna University. Their goal was to spread research freely “for scientists, by scientists’ to the rest of the world via the Open Access publishing model. The company soon became a signatory of the Budapest Initiative, which currently has more than 1000 supporting organizations worldwide, ranging from universities to funders.
\n\nAt IntechOpen today, we are still as committed to working with organizations and people who care about scientific discovery, to putting the academic needs of the scientific community first, and to providing an Open Access environment where scientists can maximize their contribution to scientific advancement. By opening up access to the world’s scientific research articles and book chapters, we aim to facilitate greater opportunity for collaboration, scientific discovery and progress. We subscribe wholeheartedly to the Open Access definition:
\n\n“By “open access” to [peer-reviewed research literature], we mean its free availability on the public internet, permitting any users to read, download, copy, distribute, print, search, or link to the full texts of these articles, crawl them for indexing, pass them as data to software, or use them for any other lawful purpose, without financial, legal, or technical barriers other than those inseparable from gaining access to the internet itself. The only constraint on reproduction and distribution, and the only role for copyright in this domain, should be to give authors control over the integrity of their work and the right to be properly acknowledged and cited” (reference: http://www.budapestopenaccessinitiative.org)
\n\nOAI-PMH
\n\nAs a firm believer in the wider dissemination of knowledge, IntechOpen supports the Open Access Initiative Protocol for Metadata Harvesting (OAI-PMH Version 2.0). Read more
\n\nLicense
\n\nBook chapters published in edited volumes are distributed under the Creative Commons Attribution 3.0 Unported License (CC BY 3.0). IntechOpen upholds a very flexible Copyright Policy. There is no copyright transfer to the publisher and Authors retain exclusive copyright to their work. All Monographs/Compacts are distributed under the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). Read more
\n\nPeer Review Policies
\n\nAll scientific works are Peer Reviewed prior to publishing. Read more
\n\nOA Publishing Fees
\n\nThe Open Access publishing model employed by IntechOpen eliminates subscription charges and pay-per-view fees, enabling readers to access research at no cost. In order to sustain operations and keep our publications freely accessible we levy an Open Access Publishing Fee for manuscripts, which helps us cover the costs of editorial work and the production of books. Read more
\n\nDigital Archiving Policy
\n\nIntechOpen is committed to ensuring the long-term preservation and the availability of all scholarly research we publish. We employ a variety of means to enable us to deliver on our commitments to the scientific community. Apart from preservation by the Croatian National Library (for publications prior to April 18, 2018) and the British Library (for publications after April 18, 2018), our entire catalogue is preserved in the CLOCKSS archive.
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\n\nWe aim at improving the quality and availability of scholarly communication by promoting and practicing:
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Currently, he is a professor of Orthodontics. He holds a Certificate of Advanced Study type A in Technology of Biomaterials used in Dentistry (1995); Certificate of Advanced Study type B in Dento-Facial Orthopaedics (1997) from the Faculty of Dental Surgery, University Denis Diderot-Paris VII, France; Diploma of Advanced Study (DESA) in Biocompatibility of Biomaterials from the Faculty of Medicine and Pharmacy of Casablanca (2002); Certificate of Clinical Occlusodontics from the Faculty of Dentistry of Casablanca (2004); University Diploma of Biostatistics and Perceptual Health Measurement from the Faculty of Medicine and Pharmacy of Casablanca (2011); and a University Diploma of Pedagogy of Odontological Sciences from the Faculty of Dentistry of Casablanca (2013). 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Radiotherapy and Nuclear Medicine Technology has always been my aspiration and my life. As years passed I accumulated a tremendous amount of skills and knowledge in Radiotherapy and Nuclear Medicine, Conventional Radiology, Radiation Protection, Bioinformatics Technology, PACS, Image processing, clinically and lecturing that will enable me to provide a valuable service to the community as a Researcher and Consultant in this field. My method of translating this into day to day in clinical practice is non-exhaustible and my habit of exchanging knowledge and expertise with others in those fields is the code and secret of success.",institutionString:null,institution:{name:"Majmaah University",country:{name:"Saudi Arabia"}}},{id:"313277",title:"Dr.",name:"Bartłomiej",middleName:null,surname:"Płaczek",slug:"bartlomiej-placzek",fullName:"Bartłomiej Płaczek",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/313277/images/system/313277.jpg",biography:"Bartłomiej Płaczek, MSc (2002), Ph.D. (2005), Habilitation (2016), is a professor at the University of Silesia, Institute of Computer Science, Poland, and an expert from the National Centre for Research and Development. His research interests include sensor networks, smart sensors, intelligent systems, and image processing with applications in healthcare and medicine. He is the author or co-author of more than seventy papers in peer-reviewed journals and conferences as well as the co-author of several books. He serves as a reviewer for many scientific journals, international conferences, and research foundations. Since 2010, Dr. Placzek has been a reviewer of grants and projects (including EU projects) in the field of information technologies.",institutionString:"University of Silesia",institution:{name:"University of Silesia",country:{name:"Poland"}}},{id:"35000",title:"Prof.",name:"Ulrich H.P",middleName:"H.P.",surname:"Fischer",slug:"ulrich-h.p-fischer",fullName:"Ulrich H.P Fischer",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/35000/images/3052_n.jpg",biography:"Academic and Professional Background\nUlrich H. P. has Diploma and PhD degrees in Physics from the Free University Berlin, Germany. He has been working on research positions in the Heinrich-Hertz-Institute in Germany. Several international research projects has been performed with European partners from France, Netherlands, Norway and the UK. He is currently Professor of Communications Systems at the Harz University of Applied Sciences, Germany.\n\nPublications and Publishing\nHe has edited one book, a special interest book about ‘Optoelectronic Packaging’ (VDE, Berlin, Germany), and has published over 100 papers and is owner of several international patents for WDM over POF key elements.\n\nKey Research and Consulting Interests\nUlrich’s research activity has always been related to Spectroscopy and Optical Communications Technology. Specific current interests include the validation of complex instruments, and the application of VR technology to the development and testing of measurement systems. He has been reviewer for several publications of the Optical Society of America\\'s including Photonics Technology Letters and Applied Optics.\n\nPersonal Interests\nThese include motor cycling in a very relaxed manner and performing martial arts.",institutionString:null,institution:{name:"Charité",country:{name:"Germany"}}},{id:"341622",title:"Ph.D.",name:"Eduardo",middleName:null,surname:"Rojas Alvarez",slug:"eduardo-rojas-alvarez",fullName:"Eduardo Rojas Alvarez",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/341622/images/15892_n.jpg",biography:null,institutionString:null,institution:{name:"University of Cuenca",country:{name:"Ecuador"}}},{id:"215610",title:"Prof.",name:"Muhammad",middleName:null,surname:"Sarfraz",slug:"muhammad-sarfraz",fullName:"Muhammad Sarfraz",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/215610/images/system/215610.jpeg",biography:"Muhammad Sarfraz is a professor in the Department of Information Science, Kuwait University. His research interests include computer graphics, computer vision, image processing, machine learning, pattern recognition, soft computing, data science, intelligent systems, information technology, and information systems. Prof. Sarfraz has been a keynote/invited speaker on various platforms around the globe. He has advised various students for their MSc and Ph.D. theses. He has published more than 400 publications as books, journal articles, and conference papers. He is a member of various professional societies and a chair and member of the International Advisory Committees and Organizing Committees of various international conferences. Prof. Sarfraz is also an editor-in-chief and editor of various international journals.",institutionString:"Kuwait University",institution:{name:"Kuwait University",country:{name:"Kuwait"}}},{id:"32650",title:"Prof.",name:"Lukas",middleName:"Willem",surname:"Snyman",slug:"lukas-snyman",fullName:"Lukas Snyman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/32650/images/4136_n.jpg",biography:"Lukas Willem Snyman received his basic education at primary and high schools in South Africa, Eastern Cape. He enrolled at today's Nelson Metropolitan University and graduated from this university with a BSc in Physics and Mathematics, B.Sc Honors in Physics, MSc in Semiconductor Physics, and a Ph.D. in Semiconductor Physics in 1987. After his studies, he chose an academic career and devoted his energy to the teaching of physics to first, second, and third-year students. After positions as a lecturer at the University of Port Elizabeth, he accepted a position as Associate Professor at the University of Pretoria, South Africa.\r\n\r\nIn 1992, he motivates the concept of 'television and computer-based education” as means to reach large student numbers with only the best of teaching expertise and publishes an article on the concept in the SA Journal of Higher Education of 1993 (and later in 2003). The University of Pretoria subsequently approved a series of test projects on the concept with outreach to Mamelodi and Eerste Rust in 1993. In 1994, the University established a 'Unit for Telematic Education ' as a support section for multiple faculties at the University of Pretoria. In subsequent years, the concept of 'telematic education” subsequently becomes well established in academic circles in South Africa, grew in popularity, and is adopted by many universities and colleges throughout South Africa as a medium of enhancing education and training, as a method to reaching out to far out communities, and as a means to enhance study from the home environment.\r\n\r\nProfessor Snyman in subsequent years pursued research in semiconductor physics, semiconductor devices, microelectronics, and optoelectronics.\r\n\r\nIn 2000 he joined the TUT as a full professor. Here served for a period as head of the Department of Electronic Engineering. Here he makes contributions to solar energy development, microwave and optoelectronic device development, silicon photonics, as well as contributions to new mobile telecommunication systems and network planning in SA.\r\n\r\nCurrently, he teaches electronics and telecommunications at the TUT to audiences ranging from first-year students to Ph.D. level.\r\n\r\nFor his research in the field of 'Silicon Photonics” since 1990, he has published (as author and co-author) about thirty internationally reviewed articles in scientific journals, contributed to more than forty international conferences, about 25 South African provisional patents (as inventor and co-inventor), 8 PCT international patent applications until now. Of these, two USA patents applications, two European Patents, two Korean patents, and ten SA patents have been granted. A further 4 USA patents, 5 European patents, 3 Korean patents, 3 Chinese patents, and 3 Japanese patents are currently under consideration.\r\n\r\nRecently he has also published an extensive scholarly chapter in an internet open access book on 'Integrating Microphotonic Systems and MOEMS into standard Silicon CMOS Integrated circuitry”.\r\n\r\nFurthermore, Professor Snyman recently steered a new initiative at the TUT by introducing a 'Laboratory for Innovative Electronic Systems ' at the Department of Electrical Engineering. The model of this laboratory or center is to primarily combine outputs as achieved by high-level research with lower-level system development and entrepreneurship in a technical university environment. Students are allocated to projects at different levels with PhDs and Master students allocated to the generation of new knowledge and new technologies, while students at the diploma and Baccalaureus level are allocated to electronic systems development with a direct and a near application for application in industry or the commercial and public sectors in South Africa.\r\n\r\nProfessor Snyman received the WIRSAM Award of 1983 and the WIRSAM Award in 1985 in South Africa for best research papers by a young scientist at two international conferences on electron microscopy in South Africa. He subsequently received the SA Microelectronics Award for the best dissertation emanating from studies executed at a South African university in the field of Physics and Microelectronics in South Africa in 1987. In October of 2011, Professor Snyman received the prestigious Institutional Award for 'Innovator of the Year” for 2010 at the Tshwane University of Technology, South Africa. This award was based on the number of patents recognized and granted by local and international institutions as well as for his contributions concerning innovation at the TUT.",institutionString:null,institution:{name:"University of South Africa",country:{name:"South Africa"}}},{id:"317279",title:"Mr.",name:"Ali",middleName:"Usama",surname:"Syed",slug:"ali-syed",fullName:"Ali Syed",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/317279/images/16024_n.png",biography:"A creative, talented, and innovative young professional who is dedicated, well organized, and capable research fellow with two years of experience in graduate-level research, published in engineering journals and book, with related expertise in Bio-robotics, equally passionate about the aesthetics of the mechanical and electronic system, obtained expertise in the use of MS Office, MATLAB, SolidWorks, LabVIEW, Proteus, Fusion 360, having a grasp on python, C++ and assembly language, possess proven ability in acquiring research grants, previous appointments with social and educational societies with experience in administration, current affiliations with IEEE and Web of Science, a confident presenter at conferences and teacher in classrooms, able to explain complex information to audiences of all levels.",institutionString:null,institution:{name:"Air University",country:{name:"Pakistan"}}},{id:"75526",title:"Ph.D.",name:"Zihni Onur",middleName:null,surname:"Uygun",slug:"zihni-onur-uygun",fullName:"Zihni Onur Uygun",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/75526/images/12_n.jpg",biography:"My undergraduate education and my Master of Science educations at Ege University and at Çanakkale Onsekiz Mart University have given me a firm foundation in Biochemistry, Analytical Chemistry, Biosensors, Bioelectronics, Physical Chemistry and Medicine. After obtaining my degree as a MSc in analytical chemistry, I started working as a research assistant in Ege University Medical Faculty in 2014. In parallel, I enrolled to the MSc program at the Department of Medical Biochemistry at Ege University to gain deeper knowledge on medical and biochemical sciences as well as clinical chemistry in 2014. In my PhD I deeply researched on biosensors and bioelectronics and finished in 2020. Now I have eleven SCI-Expanded Index published papers, 6 international book chapters, referee assignments for different SCIE journals, one international patent pending, several international awards, projects and bursaries. In parallel to my research assistant position at Ege University Medical Faculty, Department of Medical Biochemistry, in April 2016, I also founded a Start-Up Company (Denosens Biotechnology LTD) by the support of The Scientific and Technological Research Council of Turkey. Currently, I am also working as a CEO in Denosens Biotechnology. The main purposes of the company, which carries out R&D as a research center, are to develop new generation biosensors and sensors for both point-of-care diagnostics; such as glucose, lactate, cholesterol and cancer biomarker detections. My specific experimental and instrumental skills are Biochemistry, Biosensor, Analytical Chemistry, Electrochemistry, Mobile phone based point-of-care diagnostic device, POCTs and Patient interface designs, HPLC, Tandem Mass Spectrometry, Spectrophotometry, ELISA.",institutionString:null,institution:{name:"Ege University",country:{name:"Turkey"}}},{id:"267434",title:"Dr.",name:"Rohit",middleName:null,surname:"Raja",slug:"rohit-raja",fullName:"Rohit Raja",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/267434/images/system/267434.jpg",biography:"Dr. Rohit Raja received Ph.D. in Computer Science and Engineering from Dr. CVRAMAN University in 2016. His main research interest includes Face recognition and Identification, Digital Image Processing, Signal Processing, and Networking. Presently he is working as Associate Professor in IT Department, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur (CG), India. He has authored several Journal and Conference Papers. He has good Academics & Research experience in various areas of CSE and IT. He has filed and successfully published 27 Patents. He has received many time invitations to be a Guest at IEEE Conferences. He has published 100 research papers in various International/National Journals (including IEEE, Springer, etc.) and Proceedings of the reputed International/ National Conferences (including Springer and IEEE). He has been nominated to the board of editors/reviewers of many peer-reviewed and refereed Journals (including IEEE, Springer).",institutionString:"Guru Ghasidas Vishwavidyalaya",institution:{name:"Guru Ghasidas Vishwavidyalaya",country:{name:"India"}}},{id:"246502",title:"Dr.",name:"Jaya T.",middleName:"T",surname:"Varkey",slug:"jaya-t.-varkey",fullName:"Jaya T. Varkey",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/246502/images/11160_n.jpg",biography:"Jaya T. Varkey, PhD, graduated with a degree in Chemistry from Cochin University of Science and Technology, Kerala, India. She obtained a PhD in Chemistry from the School of Chemical Sciences, Mahatma Gandhi University, Kerala, India, and completed a post-doctoral fellowship at the University of Minnesota, USA. She is a research guide at Mahatma Gandhi University and Associate Professor in Chemistry, St. Teresa’s College, Kochi, Kerala, India.\nDr. Varkey received a National Young Scientist award from the Indian Science Congress (1995), a UGC Research award (2016–2018), an Indian National Science Academy (INSA) Visiting Scientist award (2018–2019), and a Best Innovative Faculty award from the All India Association for Christian Higher Education (AIACHE) (2019). She Hashas received the Sr. Mary Cecil prize for best research paper three times. She was also awarded a start-up to develop a tea bag water filter. \nDr. Varkey has published two international books and twenty-seven international journal publications. She is an editorial board member for five international journals.",institutionString:"St. Teresa’s College",institution:null},{id:"250668",title:"Dr.",name:"Ali",middleName:null,surname:"Nabipour Chakoli",slug:"ali-nabipour-chakoli",fullName:"Ali Nabipour Chakoli",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/250668/images/system/250668.jpg",biography:"Academic Qualification:\r\n•\tPhD in Materials Physics and Chemistry, From: Sep. 2006, to: Sep. 2010, School of Materials Science and Engineering, Harbin Institute of Technology, Thesis: Structure and Shape Memory Effect of Functionalized MWCNTs/poly (L-lactide-co-ε-caprolactone) Nanocomposites. Supervisor: Prof. Wei Cai,\r\n•\tM.Sc in Applied Physics, From: 1996, to: 1998, Faculty of Physics & Nuclear Science, Amirkabir Uni. of Technology, Tehran, Iran, Thesis: Determination of Boron in Micro alloy Steels with solid state nuclear track detectors by neutron induced auto radiography, Supervisors: Dr. M. Hosseini Ashrafi and Dr. A. Hosseini.\r\n•\tB.Sc. in Applied Physics, From: 1991, to: 1996, Faculty of Physics & Nuclear Science, Amirkabir Uni. of Technology, Tehran, Iran, Thesis: Design of shielding for Am-Be neutron sources for In Vivo neutron activation analysis, Supervisor: Dr. M. Hosseini Ashrafi.\r\n\r\nResearch Experiences:\r\n1.\tNanomaterials, Carbon Nanotubes, Graphene: Synthesis, Functionalization and Characterization,\r\n2.\tMWCNTs/Polymer Composites: Fabrication and Characterization, \r\n3.\tShape Memory Polymers, Biodegradable Polymers, ORC, Collagen,\r\n4.\tMaterials Analysis and Characterizations: TEM, SEM, XPS, FT-IR, Raman, DSC, DMA, TGA, XRD, GPC, Fluoroscopy, \r\n5.\tInteraction of Radiation with Mater, Nuclear Safety and Security, NDT(RT),\r\n6.\tRadiation Detectors, Calibration (SSDL),\r\n7.\tCompleted IAEA e-learning Courses:\r\nNuclear Security (15 Modules),\r\nNuclear Safety:\r\nTSA 2: Regulatory Protection in Occupational Exposure,\r\nTips & Tricks: Radiation Protection in Radiography,\r\nSafety and Quality in Radiotherapy,\r\nCourse on Sealed Radioactive Sources,\r\nCourse on Fundamentals of Environmental Remediation,\r\nCourse on Planning for Environmental Remediation,\r\nKnowledge Management Orientation Course,\r\nFood Irradiation - Technology, Applications and Good Practices,\r\nEmployment:\r\nFrom 2010 to now: Academic staff, Nuclear Science and Technology Research Institute, Kargar Shomali, Tehran, Iran, P.O. Box: 14395-836.\r\nFrom 1997 to 2006: Expert of Materials Analysis and Characterization. Research Center of Agriculture and Medicine. Rajaeeshahr, Karaj, Iran, P. O. Box: 31585-498.",institutionString:"Atomic Energy Organization of Iran",institution:{name:"Atomic Energy Organization of Iran",country:{name:"Iran"}}},{id:"248279",title:"Dr.",name:"Monika",middleName:"Elzbieta",surname:"Machoy",slug:"monika-machoy",fullName:"Monika Machoy",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/248279/images/system/248279.jpeg",biography:"Monika Elżbieta Machoy, MD, graduated with distinction from the Faculty of Medicine and Dentistry at the Pomeranian Medical University in 2009, defended her PhD thesis with summa cum laude in 2016 and is currently employed as a researcher at the Department of Orthodontics of the Pomeranian Medical University. She expanded her professional knowledge during a one-year scholarship program at the Ernst Moritz Arndt University in Greifswald, Germany and during a three-year internship at the Technical University in Dresden, Germany. She has been a speaker at numerous orthodontic conferences, among others, American Association of Orthodontics, European Orthodontic Symposium and numerous conferences of the Polish Orthodontic Society. She conducts research focusing on the effect of orthodontic treatment on dental and periodontal tissues and the causes of pain in orthodontic patients.",institutionString:"Pomeranian Medical University",institution:{name:"Pomeranian Medical University",country:{name:"Poland"}}},{id:"252743",title:"Prof.",name:"Aswini",middleName:"Kumar",surname:"Kar",slug:"aswini-kar",fullName:"Aswini Kar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/252743/images/10381_n.jpg",biography:"uploaded in cv",institutionString:null,institution:{name:"KIIT University",country:{name:"India"}}},{id:"204256",title:"Dr.",name:"Anil",middleName:"Kumar",surname:"Kumar Sahu",slug:"anil-kumar-sahu",fullName:"Anil Kumar Sahu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/204256/images/14201_n.jpg",biography:"I have nearly 11 years of research and teaching experience. I have done my master degree from University Institute of Pharmacy, Pt. Ravi Shankar Shukla University, Raipur, Chhattisgarh India. I have published 16 review and research articles in international and national journals and published 4 chapters in IntechOpen, the world’s leading publisher of Open access books. I have presented many papers at national and international conferences. I have received research award from Indian Drug Manufacturers Association in year 2015. My research interest extends from novel lymphatic drug delivery systems, oral delivery system for herbal bioactive to formulation optimization.",institutionString:null,institution:{name:"Chhattisgarh Swami Vivekanand Technical University",country:{name:"India"}}},{id:"253468",title:"Dr.",name:"Mariusz",middleName:null,surname:"Marzec",slug:"mariusz-marzec",fullName:"Mariusz Marzec",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/253468/images/system/253468.png",biography:"An assistant professor at Department of Biomedical Computer Systems, at Institute of Computer Science, Silesian University in Katowice. Scientific interests: computer analysis and processing of images, biomedical images, databases and programming languages. He is an author and co-author of scientific publications covering analysis and processing of biomedical images and development of database systems.",institutionString:"University of Silesia",institution:null},{id:"212432",title:"Prof.",name:"Hadi",middleName:null,surname:"Mohammadi",slug:"hadi-mohammadi",fullName:"Hadi Mohammadi",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/212432/images/system/212432.jpeg",biography:"Dr. Hadi Mohammadi is a biomedical engineer with hands-on experience in the design and development of many engineering structures and medical devices through various projects that he has been involved in over the past twenty years. Dr. Mohammadi received his BSc. and MSc. degrees in Mechanical Engineering from Sharif University of Technology, Tehran, Iran, and his PhD. degree in Biomedical Engineering (biomaterials) from the University of Western Ontario. He was a postdoctoral trainee for almost four years at University of Calgary and Harvard Medical School. He is an industry innovator having created the technology to produce lifelike synthetic platforms that can be used for the simulation of almost all cardiovascular reconstructive surgeries. He’s been heavily involved in the design and development of cardiovascular devices and technology for the past 10 years. He is currently an Assistant Professor with the University of British Colombia, Canada.",institutionString:"University of British Columbia",institution:{name:"University of British Columbia",country:{name:"Canada"}}},{id:"254463",title:"Prof.",name:"Haisheng",middleName:null,surname:"Yang",slug:"haisheng-yang",fullName:"Haisheng Yang",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/254463/images/system/254463.jpeg",biography:"Haisheng Yang, Ph.D., Professor and Director of the Department of Biomedical Engineering, College of Life Science and Bioengineering, Beijing University of Technology. He received his Ph.D. degree in Mechanics/Biomechanics from Harbin Institute of Technology (jointly with University of California, Berkeley). Afterwards, he worked as a Postdoctoral Research Associate in the Purdue Musculoskeletal Biology and Mechanics Lab at the Department of Basic Medical Sciences, Purdue University, USA. He also conducted research in the Research Centre of Shriners Hospitals for Children-Canada at McGill University, Canada. Dr. Yang has over 10 years research experience in orthopaedic biomechanics and mechanobiology of bone adaptation and regeneration. He earned an award from Beijing Overseas Talents Aggregation program in 2017 and serves as Beijing Distinguished Professor.",institutionString:null,institution:{name:"Beijing University of Technology",country:{name:"China"}}},{id:"89721",title:"Dr.",name:"Mehmet",middleName:"Cuneyt",surname:"Ozmen",slug:"mehmet-ozmen",fullName:"Mehmet Ozmen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/89721/images/7289_n.jpg",biography:null,institutionString:null,institution:{name:"Gazi University",country:{name:"Turkey"}}},{id:"242893",title:"Ph.D. Student",name:"Joaquim",middleName:null,surname:"De Moura",slug:"joaquim-de-moura",fullName:"Joaquim De Moura",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/242893/images/7133_n.jpg",biography:"Joaquim de Moura received his degree in Computer Engineering in 2014 from the University of A Coruña (Spain). In 2016, he received his M.Sc degree in Computer Engineering from the same university. He is currently pursuing his Ph.D degree in Computer Science in a collaborative project between ophthalmology centers in Galicia and the University of A Coruña. His research interests include computer vision, machine learning algorithms and analysis and medical imaging processing of various kinds.",institutionString:null,institution:{name:"University of A Coruña",country:{name:"Spain"}}},{id:"294334",title:"B.Sc.",name:"Marc",middleName:null,surname:"Bruggeman",slug:"marc-bruggeman",fullName:"Marc Bruggeman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/294334/images/8242_n.jpg",biography:"Chemical engineer graduate, with a passion for material science and specific interest in polymers - their near infinite applications intrigue me. \n\nI plan to continue my scientific career in the field of polymeric biomaterials as I am fascinated by intelligent, bioactive and biomimetic materials for use in both consumer and medical applications.",institutionString:null,institution:null},{id:"255757",title:"Dr.",name:"Igor",middleName:"Victorovich",surname:"Lakhno",slug:"igor-lakhno",fullName:"Igor Lakhno",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/255757/images/system/255757.jpg",biography:"Igor Victorovich Lakhno was born in 1971 in Kharkiv (Ukraine). \nMD – 1994, Kharkiv National Medical Univesity.\nOb&Gyn; – 1997, master courses in Kharkiv Medical Academy of Postgraduate Education.\nPh.D. – 1999, Kharkiv National Medical Univesity.\nDSC – 2019, PL Shupik National Academy of Postgraduate Education \nProfessor – 2021, Department of Obstetrics and Gynecology of VN Karazin Kharkiv National University\nHead of Department – 2021, Department of Perinatology, Obstetrics and gynecology of Kharkiv Medical Academy of Postgraduate Education\nIgor Lakhno has been graduated from international training courses on reproductive medicine and family planning held at Debrecen University (Hungary) in 1997. Since 1998 Lakhno Igor has worked as an associate professor in the department of obstetrics and gynecology of VN Karazin National University and an associate professor of the perinatology, obstetrics, and gynecology department of Kharkiv Medical Academy of Postgraduate Education. Since June 2019 he’s been a professor in the department of obstetrics and gynecology of VN Karazin National University and a professor of the perinatology, obstetrics, and gynecology department. He’s affiliated with Kharkiv Medical Academy of Postgraduate Education as a Head of Department from November 2021. Igor Lakhno has participated in several international projects on fetal non-invasive electrocardiography (with Dr. J. A. Behar (Technion), Prof. D. Hoyer (Jena University), and José Alejandro Díaz Méndez (National Institute of Astrophysics, Optics, and Electronics, Mexico). He’s an author of about 200 printed works and there are 31 of them in Scopus or Web of Science databases. Igor Lakhno is a member of the Editorial Board of Reproductive Health of Woman, Emergency Medicine, and Technology Transfer Innovative Solutions in Medicine (Estonia). He is a medical Editor of “Z turbotoyu pro zhinku”. Igor Lakhno is a reviewer of the Journal of Obstetrics and Gynaecology (Taylor and Francis), British Journal of Obstetrics and Gynecology (Wiley), Informatics in Medicine Unlocked (Elsevier), The Journal of Obstetrics and Gynecology Research (Wiley), Endocrine, Metabolic & Immune Disorders-Drug Targets (Bentham Open), The Open Biomedical Engineering Journal (Bentham Open), etc. He’s defended a dissertation for a DSc degree “Pre-eclampsia: prediction, prevention, and treatment”. Three years ago Igor Lakhno has participated in a training course on innovative technologies in medical education at Lublin Medical University (Poland). Lakhno Igor has participated as a speaker in several international conferences and congresses (International Conference on Biological Oscillations April 10th-14th 2016, Lancaster, UK, The 9th conference of the European Study Group on Cardiovascular Oscillations). His main scientific interests: are obstetrics, women’s health, fetal medicine, and cardiovascular medicine. \nIgor Lakhno is a consultant at Kharkiv municipal perinatal center. He’s graduated from training courses on endoscopy in gynecology. He has 28 years of practical experience in the field.",institutionString:null,institution:null},{id:"244950",title:"Dr.",name:"Salvatore",middleName:null,surname:"Di Lauro",slug:"salvatore-di-lauro",fullName:"Salvatore Di Lauro",position:null,profilePictureURL:"https://intech-files.s3.amazonaws.com/0030O00002bSF1HQAW/ProfilePicture%202021-12-20%2014%3A54%3A14.482",biography:"Name:\n\tSALVATORE DI LAURO\nAddress:\n\tHospital Clínico Universitario Valladolid\nAvda Ramón y Cajal 3\n47005, Valladolid\nSpain\nPhone number: \nFax\nE-mail:\n\t+34 983420000 ext 292\n+34 983420084\nsadilauro@live.it\nDate and place of Birth:\nID Number\nMedical Licence \nLanguages\t09-05-1985. Villaricca (Italy)\n\nY1281863H\n474707061\nItalian (native language)\nSpanish (read, written, spoken)\nEnglish (read, written, spoken)\nPortuguese (read, spoken)\nFrench (read)\n\t\t\nCurrent position (title and company)\tDate (Year)\nVitreo-Retinal consultant in ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl. National Health System.\nVitreo-Retinal consultant in ophthalmology. Instituto Oftalmologico Recoletas. Red Hospitalaria Recoletas. Private practise.\t2017-today\n\n2019-today\n\t\n\t\nEducation (High school, university and postgraduate training > 3 months)\tDate (Year)\nDegree in Medicine and Surgery. University of Neaples 'Federico II”\nResident in Opthalmology. Hospital Clinico Universitario Valladolid\nMaster in Vitreo-Retina. IOBA. University of Valladolid\nFellow of the European Board of Ophthalmology. Paris\nMaster in Research in Ophthalmology. University of Valladolid\t2003-2009\n2012-2016\n2016-2017\n2016\n2012-2013\n\t\nEmployments (company and positions)\tDate (Year)\nResident in Ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl.\nFellow in Vitreo-Retina. IOBA. University of Valladolid\nVitreo-Retinal consultant in ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl. National Health System.\nVitreo-Retinal consultant in ophthalmology. Instituto Oftalmologico Recoletas. Red Hospitalaria Recoletas. \n\t2012-2016\n2016-2017\n2017-today\n\n2019-Today\n\n\n\t\nClinical Research Experience (tasks and role)\tDate (Year)\nAssociated investigator\n\n' FIS PI20/00740: DESARROLLO DE UNA CALCULADORA DE RIESGO DE\nAPARICION DE RETINOPATIA DIABETICA BASADA EN TECNICAS DE IMAGEN MULTIMODAL EN PACIENTES DIABETICOS TIPO 1. Grant by: Ministerio de Ciencia e Innovacion \n\n' (BIO/VA23/14) Estudio clínico multicéntrico y prospectivo para validar dos\nbiomarcadores ubicados en los genes p53 y MDM2 en la predicción de los resultados funcionales de la cirugía del desprendimiento de retina regmatógeno. Grant by: Gerencia Regional de Salud de la Junta de Castilla y León.\n' Estudio multicéntrico, aleatorizado, con enmascaramiento doble, en 2 grupos\nparalelos y de 52 semanas de duración para comparar la eficacia, seguridad e inmunogenicidad de SOK583A1 respecto a Eylea® en pacientes con degeneración macular neovascular asociada a la edad' (CSOK583A12301; N.EUDRA: 2019-004838-41; FASE III). Grant by Hexal AG\n\n' Estudio de fase III, aleatorizado, doble ciego, con grupos paralelos, multicéntrico para comparar la eficacia y la seguridad de QL1205 frente a Lucentis® en pacientes con degeneración macular neovascular asociada a la edad. (EUDRACT: 2018-004486-13). Grant by Qilu Pharmaceutical Co\n\n' Estudio NEUTON: Ensayo clinico en fase IV para evaluar la eficacia de aflibercept en pacientes Naive con Edema MacUlar secundario a Oclusion de Vena CenTral de la Retina (OVCR) en regimen de tratamientO iNdividualizado Treat and Extend (TAE)”, (2014-000975-21). Grant by Fundacion Retinaplus\n\n' Evaluación de la seguridad y bioactividad de anillos de tensión capsular en conejo. Proyecto Procusens. Grant by AJL, S.A.\n\n'Estudio epidemiológico, prospectivo, multicéntrico y abierto\\npara valorar la frecuencia de la conjuntivitis adenovírica diagnosticada mediante el test AdenoPlus®\\nTest en pacientes enfermos de conjuntivitis aguda”\\n. National, multicenter study. Grant by: NICOX.\n\nEuropean multicentric trial: 'Evaluation of clinical outcomes following the use of Systane Hydration in patients with dry eye”. Study Phase 4. Grant by: Alcon Labs'\n\nVLPs Injection and Activation in a Rabbit Model of Uveal Melanoma. Grant by Aura Bioscience\n\nUpdating and characterization of a rabbit model of uveal melanoma. Grant by Aura Bioscience\n\nEnsayo clínico en fase IV para evaluar las variantes genéticas de la vía del VEGF como biomarcadores de eficacia del tratamiento con aflibercept en pacientes con degeneración macular asociada a la edad (DMAE) neovascular. Estudio BIOIMAGE. IMO-AFLI-2013-01\n\nEstudio In-Eye:Ensayo clínico en fase IV, abierto, aleatorizado, de 2 brazos,\nmulticçentrico y de 12 meses de duración, para evaluar la eficacia y seguridad de un régimen de PRN flexible individualizado de 'esperar y extender' versus un régimen PRN según criterios de estabilización mediante evaluaciones mensuales de inyecciones intravítreas de ranibizumab 0,5 mg en pacientes naive con neovascularización coriodea secunaria a la degeneración macular relacionada con la edad. CP: CRFB002AES03T\n\nTREND: Estudio Fase IIIb multicéntrico, randomizado, de 12 meses de\nseguimiento con evaluador de la agudeza visual enmascarado, para evaluar la eficacia y la seguridad de ranibizumab 0.5mg en un régimen de tratar y extender comparado con un régimen mensual, en pacientes con degeneración macular neovascular asociada a la edad. CP: CRFB002A2411 Código Eudra CT:\n2013-002626-23\n\n\n\nPublications\t\n\n2021\n\n\n\n\n2015\n\n\n\n\n2021\n\n\n\n\n\n2021\n\n\n\n\n2015\n\n\n\n\n2015\n\n\n2014\n\n\n\n\n2015-16\n\n\n\n2015\n\n\n2014\n\n\n2014\n\n\n\n\n2014\n\n\n\n\n\n\n\n2014\n\nJose Carlos Pastor; Jimena Rojas; Salvador Pastor-Idoate; Salvatore Di Lauro; Lucia Gonzalez-Buendia; Santiago Delgado-Tirado. Proliferative vitreoretinopathy: A new concept of disease pathogenesis and practical\nconsequences. Progress in Retinal and Eye Research. 51, pp. 125 - 155. 03/2016. DOI: 10.1016/j.preteyeres.2015.07.005\n\n\nLabrador-Velandia S; Alonso-Alonso ML; Di Lauro S; García-Gutierrez MT; Srivastava GK; Pastor JC; Fernandez-Bueno I. Mesenchymal stem cells provide paracrine neuroprotective resources that delay degeneration of co-cultured organotypic neuroretinal cultures.Experimental Eye Research. 185, 17/05/2019. DOI: 10.1016/j.exer.2019.05.011\n\nSalvatore Di Lauro; Maria Teresa Garcia Gutierrez; Ivan Fernandez Bueno. Quantification of pigment epithelium-derived factor (PEDF) in an ex vivo coculture of retinal pigment epithelium cells and neuroretina.\nJournal of Allbiosolution. 2019. ISSN 2605-3535\n\nSonia Labrador Velandia; Salvatore Di Lauro; Alonso-Alonso ML; Tabera Bartolomé S; Srivastava GK; Pastor JC; Fernandez-Bueno I. Biocompatibility of intravitreal injection of human mesenchymal stem cells in immunocompetent rabbits. Graefe's archive for clinical and experimental ophthalmology. 256 - 1, pp. 125 - 134. 01/2018. DOI: 10.1007/s00417-017-3842-3\n\n\nSalvatore Di Lauro, David Rodriguez-Crespo, Manuel J Gayoso, Maria T Garcia-Gutierrez, J Carlos Pastor, Girish K Srivastava, Ivan Fernandez-Bueno. A novel coculture model of porcine central neuroretina explants and retinal pigment epithelium cells. Molecular Vision. 2016 - 22, pp. 243 - 253. 01/2016.\n\nSalvatore Di Lauro. Classifications for Proliferative Vitreoretinopathy ({PVR}): An Analysis of Their Use in Publications over the Last 15 Years. Journal of Ophthalmology. 2016, pp. 1 - 6. 01/2016. DOI: 10.1155/2016/7807596\n\nSalvatore Di Lauro; Rosa Maria Coco; Rosa Maria Sanabria; Enrique Rodriguez de la Rua; Jose Carlos Pastor. Loss of Visual Acuity after Successful Surgery for Macula-On Rhegmatogenous Retinal Detachment in a Prospective Multicentre Study. Journal of Ophthalmology. 2015:821864, 2015. DOI: 10.1155/2015/821864\n\nIvan Fernandez-Bueno; Salvatore Di Lauro; Ivan Alvarez; Jose Carlos Lopez; Maria Teresa Garcia-Gutierrez; Itziar Fernandez; Eva Larra; Jose Carlos Pastor. Safety and Biocompatibility of a New High-Density Polyethylene-Based\nSpherical Integrated Porous Orbital Implant: An Experimental Study in Rabbits. Journal of Ophthalmology. 2015:904096, 2015. DOI: 10.1155/2015/904096\n\nPastor JC; Pastor-Idoate S; Rodríguez-Hernandez I; Rojas J; Fernandez I; Gonzalez-Buendia L; Di Lauro S; Gonzalez-Sarmiento R. Genetics of PVR and RD. Ophthalmologica. 232 - Suppl 1, pp. 28 - 29. 2014\n\nRodriguez-Crespo D; Di Lauro S; Singh AK; Garcia-Gutierrez MT; Garrosa M; Pastor JC; Fernandez-Bueno I; Srivastava GK. Triple-layered mixed co-culture model of RPE cells with neuroretina for evaluating the neuroprotective effects of adipose-MSCs. Cell Tissue Res. 358 - 3, pp. 705 - 716. 2014.\nDOI: 10.1007/s00441-014-1987-5\n\nCarlo De Werra; Salvatore Condurro; Salvatore Tramontano; Mario Perone; Ivana Donzelli; Salvatore Di Lauro; Massimo Di Giuseppe; Rosa Di Micco; Annalisa Pascariello; Antonio Pastore; Giorgio Diamantis; Giuseppe Galloro. Hydatid disease of the liver: thirty years of surgical experience.Chirurgia italiana. 59 - 5, pp. 611 - 636.\n(Italia): 2007. ISSN 0009-4773\n\nChapters in books\n\t\n' Salvador Pastor Idoate; Salvatore Di Lauro; Jose Carlos Pastor Jimeno. PVR: Pathogenesis, Histopathology and Classification. Proliferative Vitreoretinopathy with Small Gauge Vitrectomy. Springer, 2018. ISBN 978-3-319-78445-8\nDOI: 10.1007/978-3-319-78446-5_2. \n\n' Salvatore Di Lauro; Maria Isabel Lopez Galvez. Quistes vítreos en una mujer joven. Problemas diagnósticos en patología retinocoroidea. Sociedad Española de Retina-Vitreo. 2018.\n\n' Salvatore Di Lauro; Salvador Pastor Idoate; Jose Carlos Pastor Jimeno. iOCT in PVR management. OCT Applications in Opthalmology. pp. 1 - 8. INTECH, 2018. DOI: 10.5772/intechopen.78774.\n\n' Rosa Coco Martin; Salvatore Di Lauro; Salvador Pastor Idoate; Jose Carlos Pastor. amponadores, manipuladores y tinciones en la cirugía del traumatismo ocular.Trauma Ocular. Ponencia de la SEO 2018..\n\n' LOPEZ GALVEZ; DI LAURO; CRESPO. OCT angiografia y complicaciones retinianas de la diabetes. PONENCIA SEO 2021, CAPITULO 20. (España): 2021.\n\n' Múltiples desprendimientos neurosensoriales bilaterales en paciente joven. Enfermedades Degenerativas De Retina Y Coroides. SERV 04/2016. \n' González-Buendía L; Di Lauro S; Pastor-Idoate S; Pastor Jimeno JC. Vitreorretinopatía proliferante (VRP) e inflamación: LA INFLAMACIÓN in «INMUNOMODULADORES Y ANTIINFLAMATORIOS: MÁS ALLÁ DE LOS CORTICOIDES. RELACION DE PONENCIAS DE LA SOCIEDAD ESPAÑOLA DE OFTALMOLOGIA. 10/2014.",institutionString:null,institution:null},{id:"265335",title:"Mr.",name:"Stefan",middleName:"Radnev",surname:"Stefanov",slug:"stefan-stefanov",fullName:"Stefan Stefanov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/265335/images/7562_n.jpg",biography:null,institutionString:null,institution:null},{id:"243698",title:"Dr.",name:"Xiaogang",middleName:null,surname:"Wang",slug:"xiaogang-wang",fullName:"Xiaogang Wang",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/243698/images/system/243698.png",biography:"Dr. Xiaogang Wang, a faculty member of Shanxi Eye Hospital specializing in the treatment of cataract and retinal disease and a tutor for postgraduate students of Shanxi Medical University, worked in the COOL Lab as an international visiting scholar under the supervision of Dr. David Huang and Yali Jia from October 2012 through November 2013. Dr. Wang earned an MD from Shanxi Medical University and a Ph.D. from Shanghai Jiao Tong University. Dr. Wang was awarded two research project grants focused on multimodal optical coherence tomography imaging and deep learning in cataract and retinal disease, from the National Natural Science Foundation of China. He has published around 30 peer-reviewed journal papers and four book chapters and co-edited one book.",institutionString:null,institution:null},{id:"7227",title:"Dr.",name:"Hiroaki",middleName:null,surname:"Matsui",slug:"hiroaki-matsui",fullName:"Hiroaki Matsui",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Tokyo",country:{name:"Japan"}}},{id:"318905",title:"Prof.",name:"Elvis",middleName:"Kwason",surname:"Tiburu",slug:"elvis-tiburu",fullName:"Elvis Tiburu",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Ghana",country:{name:"Ghana"}}},{id:"336193",title:"Dr.",name:"Abdullah",middleName:null,surname:"Alamoudi",slug:"abdullah-alamoudi",fullName:"Abdullah Alamoudi",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Majmaah University",country:{name:"Saudi Arabia"}}},{id:"318657",title:"MSc.",name:"Isabell",middleName:null,surname:"Steuding",slug:"isabell-steuding",fullName:"Isabell Steuding",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Harz University of Applied Sciences",country:{name:"Germany"}}},{id:"318656",title:"BSc.",name:"Peter",middleName:null,surname:"Kußmann",slug:"peter-kussmann",fullName:"Peter Kußmann",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Harz University of Applied Sciences",country:{name:"Germany"}}},{id:"338222",title:"Mrs.",name:"María José",middleName:null,surname:"Lucía Mudas",slug:"maria-jose-lucia-mudas",fullName:"María José Lucía Mudas",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Carlos III University of Madrid",country:{name:"Spain"}}}]}},subseries:{item:{id:"1",type:"subseries",title:"Oral Health",keywords:"Oral health, Dental care, Diagnosis, Diagnostic imaging, Early diagnosis, Oral cancer, Conservative treatment, Epidemiology, Comprehensive dental care, Complementary therapies, Holistic health",scope:"
\r\n This topic aims to provide a comprehensive overview of the latest trends in Oral Health based on recent scientific evidence. Subjects will include an overview of oral diseases and infections, systemic diseases affecting the oral cavity, prevention, diagnosis, treatment, epidemiology, as well as current clinical recommendations for the management of oral, dental, and periodontal diseases.
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In recent years, the application of chemistry to biological molecules has gained significant interest in medicinal and pharmacological studies. This topic will be devoted to understanding the interplay between biomolecules and chemical compounds, their structure and function, and their potential applications in related fields. Being a part of the biochemistry discipline, the ideas and concepts that have emerged from Chemical Biology have affected other related areas. This topic will closely deal with all emerging trends in this discipline.",annualVolume:11411,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/15.jpg",editor:{id:"441442",title:"Dr.",name:"Şükrü",middleName:null,surname:"Beydemir",fullName:"Şükrü Beydemir",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003GsUoIQAV/Profile_Picture_1634557147521",institutionString:null,institution:{name:"Anadolu University",institutionURL:null,country:{name:"Turkey"}}},editorTwo:{id:"13652",title:"Prof.",name:"Deniz",middleName:null,surname:"Ekinci",fullName:"Deniz Ekinci",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYLT1QAO/Profile_Picture_1634557223079",institutionString:null,institution:{name:"Ondokuz Mayıs University",institutionURL:null,country:{name:"Turkey"}}},editorThree:null,editorialBoard:[{id:"219081",title:"Dr.",name:"Abdulsamed",middleName:null,surname:"Kükürt",fullName:"Abdulsamed Kükürt",profilePictureURL:"https://mts.intechopen.com/storage/users/219081/images/system/219081.png",institutionString:null,institution:{name:"Kafkas University",institutionURL:null,country:{name:"Turkey"}}},{id:"241413",title:"Dr.",name:"Azhar",middleName:null,surname:"Rasul",fullName:"Azhar Rasul",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRT1oQAG/Profile_Picture_1635251978933",institutionString:null,institution:{name:"Government College University, Faisalabad",institutionURL:null,country:{name:"Pakistan"}}},{id:"178316",title:"Ph.D.",name:"Sergey",middleName:null,surname:"Sedykh",fullName:"Sergey Sedykh",profilePictureURL:"https://mts.intechopen.com/storage/users/178316/images/system/178316.jfif",institutionString:null,institution:{name:"Novosibirsk State University",institutionURL:null,country:{name:"Russia"}}}]},{id:"17",title:"Metabolism",keywords:"Biomolecules Metabolism, Energy Metabolism, Metabolic Pathways, Key Metabolic Enzymes, Metabolic Adaptation",scope:"Metabolism is frequently defined in biochemistry textbooks as the overall process that allows living systems to acquire and use the free energy they need for their vital functions or the chemical processes that occur within a living organism to maintain life. Behind these definitions are hidden all the aspects of normal and pathological functioning of all processes that the topic ‘Metabolism’ will cover within the Biochemistry Series. Thus all studies on metabolism will be considered for publication.",annualVolume:11413,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/17.jpg",editor:{id:"138626",title:"Dr.",name:"Yannis",middleName:null,surname:"Karamanos",fullName:"Yannis Karamanos",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002g6Jv2QAE/Profile_Picture_1629356660984",institutionString:null,institution:{name:"Artois University",institutionURL:null,country:{name:"France"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"243049",title:"Dr.",name:"Anca",middleName:null,surname:"Pantea Stoian",fullName:"Anca Pantea Stoian",profilePictureURL:"https://mts.intechopen.com/storage/users/243049/images/system/243049.jpg",institutionString:null,institution:{name:"Carol Davila University of Medicine and Pharmacy",institutionURL:null,country:{name:"Romania"}}},{id:"203824",title:"Dr.",name:"Attilio",middleName:null,surname:"Rigotti",fullName:"Attilio Rigotti",profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institutionString:null,institution:{name:"Pontifical Catholic University of Chile",institutionURL:null,country:{name:"Chile"}}},{id:"300470",title:"Dr.",name:"Yanfei (Jacob)",middleName:null,surname:"Qi",fullName:"Yanfei (Jacob) Qi",profilePictureURL:"https://mts.intechopen.com/storage/users/300470/images/system/300470.jpg",institutionString:null,institution:{name:"Centenary Institute of Cancer Medicine and Cell Biology",institutionURL:null,country:{name:"Australia"}}}]},{id:"18",title:"Proteomics",keywords:"Mono- and Two-Dimensional Gel Electrophoresis (1-and 2-DE), Liquid Chromatography (LC), Mass Spectrometry/Tandem Mass Spectrometry (MS; MS/MS), Proteins",scope:"With the recognition that the human genome cannot provide answers to the etiology of a disorder, changes in the proteins expressed by a genome became a focus in research. Thus proteomics, an area of research that detects all protein forms expressed in an organism, including splice isoforms and post-translational modifications, is more suitable than genomics for a comprehensive understanding of the biochemical processes that govern life. The most common proteomics applications are currently in the clinical field for the identification, in a variety of biological matrices, of biomarkers for diagnosis and therapeutic intervention of disorders. From the comparison of proteomic profiles of control and disease or different physiological states, which may emerge, changes in protein expression can provide new insights into the roles played by some proteins in human pathologies. Understanding how proteins function and interact with each other is another goal of proteomics that makes this approach even more intriguing. Specialized technology and expertise are required to assess the proteome of any biological sample. Currently, proteomics relies mainly on mass spectrometry (MS) combined with electrophoretic (1 or 2-DE-MS) and/or chromatographic techniques (LC-MS/MS). MS is an excellent tool that has gained popularity in proteomics because of its ability to gather a complex body of information such as cataloging protein expression, identifying protein modification sites, and defining protein interactions. The Proteomics topic aims to attract contributions on all aspects of MS-based proteomics that, by pushing the boundaries of MS capabilities, may address biological problems that have not been resolved yet.",annualVolume:11414,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/18.jpg",editor:{id:"200689",title:"Prof.",name:"Paolo",middleName:null,surname:"Iadarola",fullName:"Paolo Iadarola",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSCl8QAG/Profile_Picture_1623568118342",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorTwo:{id:"201414",title:"Dr.",name:"Simona",middleName:null,surname:"Viglio",fullName:"Simona Viglio",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRKDHQA4/Profile_Picture_1630402531487",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorThree:null,editorialBoard:[{id:"72288",title:"Dr.",name:"Arli Aditya",middleName:null,surname:"Parikesit",fullName:"Arli Aditya Parikesit",profilePictureURL:"https://mts.intechopen.com/storage/users/72288/images/system/72288.jpg",institutionString:null,institution:{name:"Indonesia International Institute for Life Sciences",institutionURL:null,country:{name:"Indonesia"}}},{id:"40928",title:"Dr.",name:"Cesar",middleName:null,surname:"Lopez-Camarillo",fullName:"Cesar Lopez-Camarillo",profilePictureURL:"https://mts.intechopen.com/storage/users/40928/images/3884_n.png",institutionString:null,institution:{name:"Universidad Autónoma de la Ciudad de México",institutionURL:null,country:{name:"Mexico"}}},{id:"81926",title:"Dr.",name:"Shymaa",middleName:null,surname:"Enany",fullName:"Shymaa Enany",profilePictureURL:"https://mts.intechopen.com/storage/users/81926/images/system/81926.png",institutionString:"Suez Canal University",institution:{name:"Suez Canal University",institutionURL:null,country:{name:"Egypt"}}}]}]}},libraryRecommendation:{success:null,errors:{},institutions:[]},route:{name:"chapter.detail",path:"/chapters/46505",hash:"",query:{},params:{id:"46505"},fullPath:"/chapters/46505",meta:{},from:{name:null,path:"/",hash:"",query:{},params:{},fullPath:"/",meta:{}}}},function(){var e;(e=document.currentScript||document.scripts[document.scripts.length-1]).parentNode.removeChild(e)}()