Dr. Pletser’s experience includes 30 years of working with the European Space Agency as a Senior Physicist/Engineer and coordinating their parabolic flight campaigns, and he is the Guinness World Record holder for the most number of aircraft flown (12) in parabolas, personally logging more than 7,300 parabolas.
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Seeing the 5,000th book published makes us at the same time proud, happy, humble, and grateful. This is a great opportunity to stop and celebrate what we have done so far, but is also an opportunity to engage even more, grow, and succeed. It wouldn't be possible to get here without the synergy of team members’ hard work and authors and editors who devote time and their expertise into Open Access book publishing with us.
\\n\\n
Over these years, we have gone from pioneering the scientific Open Access book publishing field to being the world’s largest Open Access book publisher. Nonetheless, our vision has remained the same: to meet the challenges of making relevant knowledge available to the worldwide community under the Open Access model.
\\n\\n
We are excited about the present, and we look forward to sharing many more successes in the future.
\\n\\n
Thank you all for being part of the journey. 5,000 times thank you!
\\n\\n
Now with 5,000 titles available Open Access, which one will you read next?
Preparation of Space Experiments edited by international leading expert Dr. Vladimir Pletser, Director of Space Training Operations at Blue Abyss is the 5,000th Open Access book published by IntechOpen and our milestone publication!
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"This book presents some of the current trends in space microgravity research. The eleven chapters introduce various facets of space research in physical sciences, human physiology and technology developed using the microgravity environment not only to improve our fundamental understanding in these domains but also to adapt this new knowledge for application on earth." says the editor. Listen what else Dr. Pletser has to say...
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Dr. Pletser’s experience includes 30 years of working with the European Space Agency as a Senior Physicist/Engineer and coordinating their parabolic flight campaigns, and he is the Guinness World Record holder for the most number of aircraft flown (12) in parabolas, personally logging more than 7,300 parabolas.
\n\n
Seeing the 5,000th book published makes us at the same time proud, happy, humble, and grateful. This is a great opportunity to stop and celebrate what we have done so far, but is also an opportunity to engage even more, grow, and succeed. It wouldn't be possible to get here without the synergy of team members’ hard work and authors and editors who devote time and their expertise into Open Access book publishing with us.
\n\n
Over these years, we have gone from pioneering the scientific Open Access book publishing field to being the world’s largest Open Access book publisher. Nonetheless, our vision has remained the same: to meet the challenges of making relevant knowledge available to the worldwide community under the Open Access model.
\n\n
We are excited about the present, and we look forward to sharing many more successes in the future.
\n\n
Thank you all for being part of the journey. 5,000 times thank you!
\n\n
Now with 5,000 titles available Open Access, which one will you read next?
\n'}],latestNews:[{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"},{slug:"introducing-intechopen-book-series-a-new-publishing-format-for-oa-books-20210915",title:"Introducing IntechOpen Book Series - A New Publishing Format for OA Books"}]},book:{item:{type:"book",id:"5267",leadTitle:null,fullTitle:"Tumor Metastasis",title:"Tumor Metastasis",subtitle:null,reviewType:"peer-reviewed",abstract:"Metastasis is the major cause of cancer-related death. It is a multistep process. The mechanism underlying metastasis is complicated and poorly understood. Recent advances in tumor metastasis research have led to improved diagnosis and clinical management of cancer. However, new strategies on metastasis treatment are urgently needed, especially the novel biomarkers discovery and targeted therapy. This book is designed to present the most recent advances in tumor metastasis.",isbn:"978-953-51-2631-7",printIsbn:"978-953-51-2630-0",pdfIsbn:"978-953-51-4181-5",doi:"10.5772/61798",price:119,priceEur:129,priceUsd:155,slug:"tumor-metastasis",numberOfPages:266,isOpenForSubmission:!1,isInWos:1,isInBkci:!0,hash:"ac0d598a394585f0b00dcc15347e1f89",bookSignature:"Ke Xu",publishedDate:"September 14th 2016",coverURL:"https://cdn.intechopen.com/books/images_new/5267.jpg",numberOfDownloads:21904,numberOfWosCitations:38,numberOfCrossrefCitations:24,numberOfCrossrefCitationsByBook:0,numberOfDimensionsCitations:44,numberOfDimensionsCitationsByBook:0,hasAltmetrics:0,numberOfTotalCitations:106,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"January 25th 2016",dateEndSecondStepPublish:"February 15th 2016",dateEndThirdStepPublish:"May 13th 2016",dateEndFourthStepPublish:"June 12th 2016",dateEndFifthStepPublish:"July 12th 2016",currentStepOfPublishingProcess:5,indexedIn:"1,2,3,4,5,6,8,9",editedByType:"Edited by",kuFlag:!1,featuredMarkup:null,editors:[{id:"59529",title:"Dr.",name:"Ke",middleName:null,surname:"Xu",slug:"ke-xu",fullName:"Ke Xu",profilePictureURL:"https://mts.intechopen.com/storage/users/59529/images/system/59529.jpg",biography:"Professor Ke Xu earned his BSc degree in Microbiology from Nankai University (China), and his Ph.D. degree in Cell and Molecular Biology from University of Essex (UK). He completed his postdoctoral training at the Institute of Cancer Research (UK), studying on the induction of leukemia cell apoptosis and differentiation. Professor Ke Xu carried out his research fellowship at Imperial College London (UK), investigating gene targeting and lung cancer. He joined the Tianjin Lung Cancer Institute of Tianjin Medical University General Hospital (China) in 2007 as a principle investigator to establish an independent research group, studying the molecular mechanism of metastasis and chemoresistance of lung cancer. He also develops novel chemical compounds to interfere with key cancer promoting pathways. Professor Ke Xu is an active member of American Association for Cancer Research, European Association for Cancer Research, American Society for Cell Biology, Chinese Anti-Cancer Association, Chinese Society for Cell Biology, and Chinese Pharmaceutical Association.",institutionString:"Tianjin Medical University General Hospital",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"0",totalChapterViews:"0",totalEditedBooks:"2",institution:{name:"Tianjin Medical University General Hospital",institutionURL:null,country:{name:"China"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"411",title:"Cancer Biology",slug:"biochemistry-genetics-and-molecular-biology-microbiology-cancer-biology"}],chapters:[{id:"51889",title:"Hemostatic System in Malignancy: Providing the “Soil” in Metastatic Niche Formation",doi:"10.5772/64697",slug:"hemostatic-system-in-malignancy-providing-the-soil-in-metastatic-niche-formation",totalDownloads:1606,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:"Malignancy arises and progresses in tight association with changes in the tumor microenvironment and deregulation of hemostatic system. Cancer induces hemostatic imbalance through production and secretion of procoagulant substances, suppression of anticoagulant mechanisms, endothelial activation, and angiogenic switch. Cancer cells are equipped with certain coagulation signaling receptors such as tissue factor (TF) and urokinase plasminogen activator receptor (uPAR). Tissue factor: as major initiator of coagulation, TF is considered the main cause for hypercoagulability in cancer. Constitutive TF expression by cancer cells is a hallmark of malignancy rendering tumors proangiogenic and prometastatic. TF fosters metastasis through coagulation-dependent pathways leading to fibrin deposition in the evolving premetastatic niche. TF has been identified as an independent predictor for metastatic development and adverse prognosis. uPAR: Tissue overexpression of uPAR is demonstrated in almost all human cancers and is associated with advanced disease. Increased uPAR expression is driven by molecular events involving K-ras and SRC oncogenes. Transactivation of these receptors, mediated by binding to hemostatic proteins, activates intracellular signaling pathways, modulates gene expression and facilitates processes of tumor initiation, epithelial-to-mesenchymal transition, anoikis, and metastasis. By manipulating hemostatic processes, tumor induces tolerant host environment necessary for evasion of defense attacks, survival, and progression.",signatures:"Elina Beleva, Veselin Popov and Janet Grudeva-Popova",downloadPdfUrl:"/chapter/pdf-download/51889",previewPdfUrl:"/chapter/pdf-preview/51889",authors:[{id:"185398",title:"Dr.",name:"Elina",surname:"Beleva",slug:"elina-beleva",fullName:"Elina Beleva"},{id:"185444",title:"Prof.",name:"Zhanet",surname:"Grudeva-Popova",slug:"zhanet-grudeva-popova",fullName:"Zhanet Grudeva-Popova"},{id:"185475",title:"Dr.",name:"Veselin",surname:"Popov",slug:"veselin-popov",fullName:"Veselin Popov"}],corrections:null},{id:"51782",title:"Is Extracellular Matrix a Castle Against to Invasion of Cancer Cells?",doi:"10.5772/64495",slug:"is-extracellular-matrix-a-castle-against-to-invasion-of-cancer-cells-",totalDownloads:2290,totalCrossrefCites:2,totalDimensionsCites:4,hasAltmetrics:0,abstract:"Metastasis is a complicated course that involves the spread of a neoplasm to distant parts of the body from its original site. A cancer cell must complete a series of steps before it becomes a clinically detectable lesion for successful colonization in the body. These are separation from the primary tumor, invasion and penetration of their basement membranes, entry into the blood vessels and survival within blood, and entry into lymphatics. A major challenge in extracellular matrix (ECM) biology is to understand the roles of the ECM and how disruption of ECM dynamics may contribute to cancer. A noteworthy area of forthcoming cancer research will be to determine whether abnormal ECM could be an effective cancer therapeutic target. We should understand how ECM composition and organization are normally maintained and how they may be deregulated in cancer. So the aims of this chapter were to focus on extracellular matrix. Invasion and metastatic skills, properties and functions of the ECM, abnormal ECM dynamics, tumor microenvironment and ECM, details of ECM invasion, role of ECM and ECM‐associated proteins in metastasis, tumor dormant and metastatic process, essential component of the niches, role of the ECM in tumor angiogenesis and lymphangiogenesis are be briefly explained in this chapter.",signatures:"Serdar Altınay",downloadPdfUrl:"/chapter/pdf-download/51782",previewPdfUrl:"/chapter/pdf-preview/51782",authors:[{id:"185324",title:"Associate Prof.",name:"Serdar",surname:"Altınay",slug:"serdar-altinay",fullName:"Serdar Altınay"}],corrections:null},{id:"51874",title:"Ovarian Cancer Metastasis: A Unique Mechanism of Dissemination",doi:"10.5772/64700",slug:"ovarian-cancer-metastasis-a-unique-mechanism-of-dissemination",totalDownloads:3066,totalCrossrefCites:12,totalDimensionsCites:21,hasAltmetrics:0,abstract:"Ovarian cancer is the most lethal of all gynecologic malignancies and has witnessed minimal improvements in patient outcomes in the past three decades. About 70% of ovarian cancer patients present with disseminated disease at the time of diagnosis. The standard of care remains a combination of debulking surgery and platinum‐ and taxanes‐based cytotoxic chemotherapy. Even though metastasis is the leading cause of ovarian cancer related fatalities, our understanding of the process remains limited. Ovarian cancer has a unique pattern of metastasis where the hematogenous spread is less common. Ovarian cancer cells mainly metastasize within the peritoneal cavity, which involves exfoliation from the primary tumor, survival, and transport in the peritoneal fluid followed by metastatic colonization of the organs within the peritoneal cavity. A key step for successful metastasis is their attachment and productive interactions with the mesothelial cells covering the metastatic organs for the establishment of metastatic tumors. This chapter provides an overview of ovarian cancer metastasis highlighting the unique dissemination and the underlying mechanisms of regulation of the steps involved. The role of the microenvironment in the process of metastasis will also be reviewed.",signatures:"Anirban K. Mitra",downloadPdfUrl:"/chapter/pdf-download/51874",previewPdfUrl:"/chapter/pdf-preview/51874",authors:[{id:"185152",title:"Dr.",name:"Anirban",surname:"Mitra",slug:"anirban-mitra",fullName:"Anirban Mitra"}],corrections:null},{id:"51956",title:"Role of Aquaporins in Breast Cancer Progression and Metastasis",doi:"10.5772/64446",slug:"role-of-aquaporins-in-breast-cancer-progression-and-metastasis",totalDownloads:1943,totalCrossrefCites:2,totalDimensionsCites:3,hasAltmetrics:0,abstract:"There are various limitations regarding the current pharmacological options for the treatment of breast cancer in terms of efficacy, target selectivity, side effect profile and survival. Endocrine-based therapy for hormone-sensitive cancers such as that of the breast is one of the most effective and well-tolerated therapeutic options but is hampered by either intrinsic or acquired resistance, resulting in a more aggressive form of the disease. It is generally agreed that this process occurs in parallel with cellular transition from epithelial to mesenchymal phenotype (EMT), with consequent enhancement of proliferative capacity, migrative ability and invasive potential. Aquaporins (AQPs) represent a large family of water channel proteins which are widely distributed in various tissues and which play a role in the physiological maintenance of the extracellular environment particularly to regulate electrolyte-water balance. Accumulating evidence shows that expression of several AQPs is modulated in cancer tissues, and this correlates with tumor grade. AQPs 1 and 3–5 are also involved in breast cancer invasion, through modulating the activity of various growth factors, signaling molecules and proteolytic enzymes. We review current data on the involvement of these proteins in processes associated with malignant progression and discuss possible applications of AQP-based therapy as an effective means of inhibiting cancer cells from metastasizing.",signatures:"Maitham A. Khajah and Yunus A. Luqmani",downloadPdfUrl:"/chapter/pdf-download/51956",previewPdfUrl:"/chapter/pdf-preview/51956",authors:[{id:"40180",title:"Prof.",name:"Yunus",surname:"Luqmani",slug:"yunus-luqmani",fullName:"Yunus Luqmani"},{id:"173123",title:"Dr.",name:"Maitham",surname:"Khajah",slug:"maitham-khajah",fullName:"Maitham Khajah"}],corrections:null},{id:"51684",title:"Extracellular Vesicles: A Mechanism to Reverse Metastatic Behaviour as a New Approach to Cancer Therapy",doi:"10.5772/64391",slug:"extracellular-vesicles-a-mechanism-to-reverse-metastatic-behaviour-as-a-new-approach-to-cancer-thera",totalDownloads:1871,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Extracellular vesicles (EVs) are membrane-bound particles shed from nearly all cell types into the extracellular environment. This collective term includes vesicles ranging in size from 30 nm to 5 μm in diameter. Various isolation techniques are used in different studies to separate EVs with no consensus protocol. EVs are released from cells under normal physiological conditions as well as in stressful and pathological conditions. In malignancies, they have been shown to be useful circulating markers for risk assessment, early diagnosis, monitoring of therapeutic effectiveness and prognosis. In addition, they appear to influence cell death and growth, angiogenesis, immune surveillance, extracellular matrix degradation and metastasis. In this respect, EVs have generated considerable interest for their potential use in cancer therapeutics. Since they appear to be responsible for transference of cellular components between cells and thereby transfer of functional characteristics of the donor to the recipient, two strategies for their role in cancer therapeutics may be envisaged. The first would be to prevent formation and/or shedding of EVs to prevent communication to or from cancer cells. The second would be to utilize them as carriers to deliver inhibitory/toxic components into cancer cells to destroy or neutralize them. In this review, we discuss the current state of research on characterization of EVs and highlight possible strategies for their use in cancer therapy.",signatures:"Monerah Al Soraj, Salma Bargal and Yunus A. Luqmani",downloadPdfUrl:"/chapter/pdf-download/51684",previewPdfUrl:"/chapter/pdf-preview/51684",authors:[{id:"185255",title:"Prof.",name:"Yunus",surname:"Luqmani",slug:"yunus-luqmani",fullName:"Yunus Luqmani"},{id:"185459",title:"Dr.",name:"Monerah",surname:"Al Soraj",slug:"monerah-al-soraj",fullName:"Monerah Al Soraj"}],corrections:null},{id:"51715",title:"Modulation of Gene Expression During Stages of Liver Colonization by Pancreatic Cancer in a Rat Model",doi:"10.5772/64335",slug:"modulation-of-gene-expression-during-stages-of-liver-colonization-by-pancreatic-cancer-in-a-rat-mode",totalDownloads:1346,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Pancreatic ductal adenocarcinoma (PDAC) is known for its early spreading of tumor cells into the liver. The aim of this study was to investigate the modulated gene expression of PDAC cells during liver colonization. To that purpose, ASML rat pancreatic cancer cells marked with enhanced green fluorescent protein were inoculated into the portal vein of isogenic BDX rats and reisolated from livers by fluorescence-activated cell sorting sorting at early (1, 3 days), intermediate (9 days), advanced (15 days), and terminal (21 days) stages of liver colonization. Reisolated ASML cells were used for total RNA isolation and subsequently their gene expression was investigated by Illumina chip array for mRNA and miRNA species, followed by Ingenuity Pathway Analysis (IPA). Following reisolation, 7–20% of genes and 10% of miRNA species were modulated significantly in expression during the early stage of liver colonization and continuously thereafter. These overall changes led to distinguish certain categories and processes participating in cancer progression. The knowledge of these alterations in gene expression will suggest targets, which could be used for new diagnostic procedures as well as for combating liver metastasis successfully.",signatures:"Khamael M.K. Al-Taee, Hassan Adwan and Martin R. Berger",downloadPdfUrl:"/chapter/pdf-download/51715",previewPdfUrl:"/chapter/pdf-preview/51715",authors:[{id:"56407",title:"Prof.",name:"Martin",surname:"Berger",slug:"martin-berger",fullName:"Martin Berger"}],corrections:null},{id:"51761",title:"Minimal Invasive Surgery of Metastatic Bone Tumor",doi:"10.5772/64341",slug:"minimal-invasive-surgery-of-metastatic-bone-tumor",totalDownloads:1621,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Bone is one of the most common metastatic areas in the cancer patient. Bone metastasis is the major cause to deteriorate the quality of life due to severe pain, walking difficulty, paraplegia, and pathologic fracture. To maintain patient’s general condition and continue scheduled medical treatment, various minimally invasive surgical methods have been developed. The percutaneous methods including alcohol or bone cement (polymethyl methacrylate [PMMA]) injection, laser or radiofrequency ablation, cryosurgery, and MRI-HIFU have shown favorable outcomes in the spine, pelvis, and other flat bones. Using only these percutaneous methods have high risk of pathologic fracture in the long bone of extremity, which needs some metallic fixation. Therefore, the new surgical method and instrument involving percutaneous internal fixation with PMMA bone cement injection have been introduced. The PMMA bone cement injection is effective in the metastatic bone tumor, providing reliable mechanical augmentation of destructive bone, durable local tumor suppression, and effective pain relief. The hollow-perforated screw and nail (multihole injection screw and nail) has central canal and multiple side holes to facilitate injection of bone cement to the bone lesion. An optimal customized surgical option according to the patient’s circumstances should be planned.",signatures:"Hyun Guy Kang and San Ha Kang",downloadPdfUrl:"/chapter/pdf-download/51761",previewPdfUrl:"/chapter/pdf-preview/51761",authors:[{id:"24542",title:"Prof.",name:"Hyun Guy",surname:"Kang",slug:"hyun-guy-kang",fullName:"Hyun Guy Kang"},{id:"190939",title:"Ms.",name:"San Ha",surname:"Kang",slug:"san-ha-kang",fullName:"San Ha Kang"}],corrections:null},{id:"51880",title:"The Selection Strategy for Circulating Tumor Cells (CTCs) Isolation and Enumeration: Technical Features, Methods, and Clinical Applications",doi:"10.5772/64812",slug:"the-selection-strategy-for-circulating-tumor-cells-ctcs-isolation-and-enumeration-technical-features",totalDownloads:1832,totalCrossrefCites:2,totalDimensionsCites:5,hasAltmetrics:0,abstract:"The key aim of the proposed chapter is to provide readers a brief description for the most important parts of the field of circulating tumor cells (CTCs): the core techniques, including negative and positive selection‐based CTC isolation, and the differences between them. Most importantly, we will also review the clinical applications and important findings in clinical trials. The evidence‐based review will not only help clinicians use CTCs to predict recurrence and foresee the disease‐related outcomes but also to inspire the researchers in this field to conduct further investigations.",signatures:"Jason Chia‐Hsun Hsieh and Tyler Ming‐Hsien Wu",downloadPdfUrl:"/chapter/pdf-download/51880",previewPdfUrl:"/chapter/pdf-preview/51880",authors:[{id:"182712",title:"Dr.",name:"Chia-Hsun",surname:"Hsieh",slug:"chia-hsun-hsieh",fullName:"Chia-Hsun Hsieh"}],corrections:null},{id:"51371",title:"Detection of Circulating Tumor Cells and Circulating Tumor Stem Cells in Breast Cancer by Using Flow Cytometry",doi:"10.5772/63423",slug:"detection-of-circulating-tumor-cells-and-circulating-tumor-stem-cells-in-breast-cancer-by-using-flow",totalDownloads:1762,totalCrossrefCites:0,totalDimensionsCites:1,hasAltmetrics:0,abstract:"We demonstrated the value of multiparameter flowcytometry in detecting human tumor cells of breast cancer in peripheral blood, which had a sensitivity limit of 10-5 and higher specificity compares with real‐time polymerase chain reaction (RT‐PCR). It was also found that circulating tumor cell (CTC) number was related with TNM stage, metastasis and the overall survival of patients. CTC level was one of the important factors for patients’ prognosis. At the same time, we also verified the circulating tumor stem cell (CTSC) was connected with TNM stage by multiparameter cytometry. The detection of CTC and CTSC by multiparameter flowcytometry may be used to diagnose disease at early stage to guide clinical therapy or to predict prognosis. Multiparameter flowcytometry has the potential to be a valuable tool for prognosis assessment among patients with breast cancer in clinical situation in China.",signatures:"Yanjie Hu, Jin’e Zheng and Shiang Huang",downloadPdfUrl:"/chapter/pdf-download/51371",previewPdfUrl:"/chapter/pdf-preview/51371",authors:[{id:"182055",title:"Prof.",name:"Shiang",surname:"Huang",slug:"shiang-huang",fullName:"Shiang Huang"},{id:"185678",title:"Dr.",name:"Yanjie",surname:"Hu",slug:"yanjie-hu",fullName:"Yanjie Hu"},{id:"185679",title:"Dr.",name:"Jin’e",surname:"Zheng",slug:"jin'e-zheng",fullName:"Jin’e Zheng"}],corrections:null},{id:"51972",title:"Epithelial-Mesenchymal Transition and its Regulation in Tumor Metastasis",doi:"10.5772/64497",slug:"epithelial-mesenchymal-transition-and-its-regulation-in-tumor-metastasis",totalDownloads:2661,totalCrossrefCites:5,totalDimensionsCites:7,hasAltmetrics:0,abstract:"Epithelial-mesenchymal transition (EMT) plays a key role in cancer metastasis. This process is a complex, multi-functional, and tightly regulated developmental program. EMT has been extensively investigated, but the molecular regulation of its signaling pathway is highly complex. In this study, the different elements of EMT cascades that could be targeted were determined. Difficulties in translating the preclinical findings in routine clinic were also distinguished. Future research will provide insights into the activation and regulation of various EMT programs in different tumor types and at distinct stages of tumor development. These results will likely facilitate the development of early detection strategies and improve the therapeutic targeting of malignant solid tumors.",signatures:"Tao Sun, Yuan Qin and Wei-long Zhong",downloadPdfUrl:"/chapter/pdf-download/51972",previewPdfUrl:"/chapter/pdf-preview/51972",authors:[{id:"184913",title:"Associate Prof.",name:"Tao",surname:"Sun",slug:"tao-sun",fullName:"Tao Sun"},{id:"184922",title:"Dr.",name:"Yuan",surname:"Qin",slug:"yuan-qin",fullName:"Yuan Qin"},{id:"184923",title:"Dr.",name:"Wei-Long",surname:"Zhong",slug:"wei-long-zhong",fullName:"Wei-Long Zhong"}],corrections:null},{id:"51771",title:"Importance and Detection of Epithelial-to-Mesenchymal Transition (EMT) Phenotype in CTCs",doi:"10.5772/64342",slug:"importance-and-detection-of-epithelial-to-mesenchymal-transition-emt-phenotype-in-ctcs",totalDownloads:1911,totalCrossrefCites:0,totalDimensionsCites:2,hasAltmetrics:0,abstract:"The current dogma is that epithelial-to-mesenchymal transition (EMT) promotes circulating tumour cell (CTC) formation and is ultimately a driver of metastasis. There is also accumulating evidence that EMT-phenotype changes are commonly associated with therapy resistance. Thus, capturing EMT-phenotype CTCs is expected to yield important clinical information in regard to prognosis and response to therapy as well as allowing the study of metastatic processes. However, the isolation and identification of EMT-phenotype CTCs with commonly used isolation/detection methods are suboptimal, and current efforts on improving the isolation of EMT-phenotype CTCs are associated with pitfalls that need to be overcome. This chapter explores the significance of EMT in CTC formation and the role of EMT in cancer metastasis and resistance to therapy. We also comprehensively review the past and current limitations of evaluating EMT phenotypes in CTC isolation and analysis and discuss how CTCs can be seen in a more holistic fashion as important biomarkers for clinical management.",signatures:"Joseph W. Po, David Lynch, Paul de Souza and Therese M. 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1. Introduction
The commercialization of public land in the Global South, which refers to the medium and low human development based on the United Nations development program report 2005 [1], has increased dramatically in recent years due to the wide spread leasing and sale of land to foreign companies and governments. The main goal of these investors is to secure food and energy production for their populations as multiple factors threaten their food security at home. On the one hand, the current population will increase worldwide from nearly 7 billion to over 9 billion by 2050 [2], a growth that would require the increase of food production from nearly 6 billion tons (gross) to 9 billion tons by 2050 [3]. Furthermore, competition for land, water, and energy will only intensify along with the need to reduce the many negative impacts of agriculture to the environment [4, 5]. Global food security has been further strained, notably during 2007-08 [6], by the growing volatility of the food market and the political controversy surrounding the use of grain to produce biofuels [7, 8]. Any one of these factors will likely pose significant challenges, but the sum of all of them could constitute a major threat to land ownership.
Overall, these factors have driven a change in perspectives of land ownership. Recent trends indicate that the need to provide food and energy security at home has led international corporations, sovereign wealth funds, foreign governments, private equity firms and domestic actors to buy or lease large tracts of land outside their national borders [9]. These land deals or “land grabbing”, as labeled by many Non-Governmental Organizations and the media, are certainly to be considered a prominent factor in the list of significant drivers of land change in certain parts of the globe, especially in southern hemisphere continents. The need to secure food supply comes as a result of the many international pressures that took place in the mid-2000s; and initiated the rise of food prices by 2006. Among these pressures some that stand out are [10]:
Extreme weather events, such as droughts and floods that affected cereal exports in 2005-06 and decreased cereal production worldwide by 10 percent.
World cereal reserves fell as major cereal producers such as the USA, EU and China reduced holdings of food stocks.
Fertilizer prices and transportation costs increased due to the oil price hike from 2003 to 2008.
The increased demand for the production of biofuels conflicted with food crops as land was diverted for the production of monocultures such as sugar, oilseeds, palm oil and maize.
These, along with other international and local pressures caused concern in the international market leading to an increase in market volatility as speculations of food supply where unfavorable [10]. In response to these price hikes many food-importing countries found a long term strategy to outsource their food production and guarantee their food supply at low costs in the leasing and purchasing of foreign land [11]. For example, China holds approximately 20 percent of the world’s population but possesses no more than seven percent of the world’s arable land [12]. For many years this Asian country has been a net exporter of agricultural goods. In recent years due to its rapid economic growth, higher population income, changes in diets, and limited arable land, among other factors, China has become a net importer of agricultural goods since the beginning of the 2000s. In order to ensure its food security and promote its current economic growth the Chinese government and private corporations are investing in land suitable for agriculture outside its national borders. In the same way some wealthy import-dependent countries, such as Japan and South Korea being directly affected by the 2007-08 food crises, have initiated policies along this line. On the other hand, arid, oil-rich countries from the Gulf States under “harsh climatic conditions, poor soils and scarce land and water” among other limitations [11], such as Saudi Arabia, do so in an attempt to reduce its domestic water use [13]. In recent years the scale of this type of business has increased dramatically with millions of hectares being bought or leased outside their borders. [11]
Due to the increasing global demand for food-stuffs production and alternative energy development, the southern hemisphere is portrayed as an idoneous reservoir of arable land capable of satisfying the international needs, a particular example constitute African countries due to their relatively low population density [9] and cheap land. As mentioned in De Shutter (2009) southern countries in Africa and Latin America are the main targets for investors seeking farmland as it is scarce in Asia [14]. This race to buy land has been described by many as a new neo-colonial approach by wealthy countries to take over the key natural resources of poor countries [15]. Some analysts perceive these land deals as a threat to the livelihood of local communities while others stress the positive effects derived from the income generated in these deals [9]. Such benefits could be perceived as the injection of the much-needed capital to sustain agriculture [16] and therefore the creation of on-farm and off-farm jobs, the development of rural infrastructure such as irrigation canals, and the construction of schools and health clinics that will improve local livelihoods. Along this line of thought, many of the host countries of land deals have encouraged this type of investment and are keen to develop it as a potentially lucrative activity [6].
2. Global land grabs
2.1. Land grabs undermine food security
Global land grabs have recently become a major point of international discussion [17] due to the global struggle to ensure food security [18]. “Land grabbing, generally referred to the mass purchase of agricultural lands by transnational companies or foreign countries” [19], refers to the lease (often for 30–99 years) or purchase of vast areas of land outside their national borders [20] mainly for agricultural production. One of the main drivers of this practice is the current international demand for cheap food after the food price hikes of 2007-08 [13]. During these years the dramatic increase in basic food prices reduced the access to food of millions of people as they reached the highest levels in 30 years [21]. According to global estimates this price hike brought around 915 million people to undernourished levels worldwide, and additional hundreds of millions were added to the count due to the effects of the global financial and economic crisis [10]. Although the highest levels of food insecurity where reached in developing nations many food-importing countries felt the effects of food prices in their own population.
According to Brown (2011), wealthy but food-insecure countries worried about tightening markets [20] are seeking to ensure their food production by leasing and buying land overseas (e.g. the Gulf States). By controlling farm land beyond their national borders these countries are gaining control of the international supply-chain of food-stuffs [22]. This practice is perceived as an innovative, long-term strategy to ensure the food security of its population at cheap prices [20]. The majority of the investors are Asian countries such as China and India, which according to the Food and Agriculture Organization\'s (FAO) 2009 report, are currently food self-sufficient. Likewise import dependant countries, particularly affected by the food crisis, such as Saudi Arabia, Japan and South Korea, are also in the search for fertile farmland in African countries like Uganda, Madagascar, Mali, Somalia, Sudan and Mozambique, as well as in other developing countries such as the Philippines, Indonesia, Laos, Thailand, Vietnam, Cambodia, Pakistan, Burma, Brazil, Argentina, Kazakhstan, Ukraine, etc. [16, 20, 23]. (Table1. Shows the most recent estimates of land deals worldwide linked to the countries that are the major sources of land grabbers).
The governments of ‘host’ countries, such as Madagascar, Sudan and Cambodia, generally welcome foreign investment [24], even though much of their own population lacks sufficient food [17]. Large-scale land acquisition for food security by richer countries is increasingly contested, since it is not considered ethical to export food from countries in which there is widespread hunger. For example, Daewoo Logistics, the South Korean commercial group, failed its attempts to acquire 1.3 million hectares (over half the arable land of the country) of land in Madagascar for the production of maize for human consumption food and palm oil used in biofuels [16]. By doing this the company would have ensured future fuel stocks and guaranteed the countries’ food security “by providing half of its maize imports from Madagascar alone” [25]. Ultimately the deal ran into trouble and was a direct factor in the overthrow of the country’s government in 2009 [16].
Countries involved in land grabbing
Land purchased or leased (including deals still in process in ha)
Number of deals
UK
4,941,765
40
US
4,162,394
42
UAE
3,182,950
19
India
2,101,400
28
China
1,953,527
36
South Korea
1,412,394
16
Saudi Arabia
1,132,945
20
Germany
525,345
22
Table 1.
2012 global estimates of major land deals carried out by governments and private companies.
In developing countries, land deals result most of the time in the displacement, dispossession and disenfranchisement of local communities. Most of the land utilized by small farmers in local communities is used under customary tenure arrangements; as a consequence, they often lack formal property titles over the land and can easily risk losing access to it [9]. In addition, most of the deals between foreign investors and local governments are arranged outside the public scope and therefore, smallholders may not even know they are losing their land. Women, who make up 70 percent of farmers in the developing world, are often the most vulnerable to this practice as they may not be able to protect their own land tenure claims in court due to local laws.
The general perception under the land deals scope is that most of the land available for buyers is abundant and underutilized; although in many cases it is already being used [6]. Existing land use it usually overlooked due to the lack of formal land rights of smallholders or their access to proper legal assistance [16]. For example, in Gambela, Ethiopia, the Ethiopian government has signed deals with investors from India, Saudi Arabia, China and other countries since 2008 for large-scale agricultural projects in the region (see Table 1). The deals give foreign investors control of half of Gambela\'s arable land [26]. All land allocations recorded are classified as involving ‘wastelands’ with no pre-existing users. As the Anywaa Survival Organization was able to verify, these are ancestral lands from which indigenous communities such as the Anuak have been dislocated. Without any information or consent for the sale and purchase of such territories, the surrounding communities have lost from these forests their refuge in times of violence, an excellent source of medicinal plants, and a valuable reserve of food during famines [26].
Land grabber
Base
Sector
Hectares
Production
Projected Investment
Status of the deal
Hunan Dafengyuan
China
Agribusiness
25,000
Sugar Cane
-------------
Completed
ARS Agrofoods
India
Agribusiness
3,000
Cotton, groundnut, sesame, soybean
US $5 million
In process
BHO Agro
India
Agribusiness
27,000
Cereal, oil seeds, pulses
US $8/ha/yr (lease)
Completed
Karuturi
India
Agribusiness
311,000
Maize, palm oil, rice, sugar
US $1.2/ha/yr (after first 7 years)
Completed
Ruchi Group
India
Agribusiness
50,000
Soybeans
US $4 million (lease cost for 25,000 ha)
Completed
Al Amoudi
Saudi Arabia
Finance
140,000
Livestock, maize, oilseeds, rice sugar cane, teff
US $2,500 million
Completed
Table 2.
Examples of land deals initiated in Gambela since 2008.
These large-scale land deals increase local food insecurity as the export of locally produced agricultural products force farmers to purchase agricultural goods elsewhere as opposed to benefiting from the harvest of their own lands [27]. The country of Ethiopia claimed as the epicenter of current land deals [29], shows the direct relationship between food insecurity and land grabs. Since 1984, Ethiopia has been well known for its extreme food shortages [22]. In 2010 ten percent of its population relied on food aid [27], and in 2011, due to the dearth of rain in the Somali and Oromiya regions, the nation appealed for emergency food aid at the United Nations. Betting on economic growth projections, the Ethiopian government promised that the country would be food self-sufficient within five years. Although the economic speculation is promising it comes at the expense of the displacing and dispossession of the population as the government is closing deals with private investors over the citizen’s lands [22]. The detrimental effects of these land deals were evident during the 2008 famine in which food instability levels increased among the population while food was being exported [30]. The USAID, which has been one of Ethiopia’s largest aid donors, is strong critic to this practice, and argues that the right way to ensure the country’s food security is by guaranteeing the complete ownership of land by its citizens and to stimulate the local consumption [31]. Nevertheless, the irony of these land deals continued as a $116-million food aid package is planned to reach the African nation for a five-year period, while, contradictorily in 2009 there was a simultaneous $100-million Saudi investment to grow and export rice, wheat and barley back to itself [22].
2.2. The “food and biofuels conflict”
The recent global awareness of anthropogenic climate change and the resulting growing interest in green energy, including biofuels, have been another important motivation for land investments. Currently biofuel production is the dominant reason for land deals in countries such as Madagascar and Ethiopia, where jatropha, palm oil and sugar are major crops. According to the Global Land Report 2010 (GLP) biofuels production is an important driver for the international land investments in Africa [9]. These deals are driven in part by the international demand for renewable fuels and the shifts in energy policy among Southern African countries to fulfill their energy needs with their own natural resources [32]. This growing interest on green energy is leading investors to invest in productive land overseas which results in the opening of new land for agriculture [9]. Many see this as a strategy by the private sector to take advantage of the emerging market of green energy. For instance, countries like China wish to diversify its domestic energy sector [9] due to the increasing demand of oil and its high global prices. Hence, the growing production of biofuels has started to affect the current food production as land deals keep taking place in the international scope.
On the other hand, many Southern African countries have actively embraced the biofuels productions in their lands, as they wish to limit their dependence on future oil imports and exposure to price volatility [32] by becoming oil producers. Mozambique is a perfect example. With the goal of becoming an ‘oil exporting country’ on 2004 the Mozambique government urged farmers to plant jatropha - a Latin American shrub which seeds produce an oil that upon extraction can be refined to produce biodiesel - on all marginal and unused lands [33]. Although there is evidence that this crop will perform poorly under harsh agro-ecological conditions, the building of cultivation and processing facilities for the production of biodiesel derived from this plant have been initiated.
2.3. Seeking land and water
When seeking arable land overseas foreign investor’s main targets are lands with access to irrigation for better potential production of food or biofuels [13]. According to the International Institute for Sustainable Development, the ultimate goal of the purchase or long-term lease of land in foreign countries is the acquisition of the water rights [34]. This practice allows major investor countries facing water scarcity to shift their domestic irrigation water to municipal water supplies [13]. We find China, India, Saudi Arabia, Kuwait, Qatar, and Bahrain among this type of investors group. African and Asian countries rich in land and water resources are the primary targets for their land investments [6]. For example, Central Africa only uses irrigation resources in two percent of its land, making an investment in this untapped water resource a very appealing proposition [35]. However, as abundant as water may seem, predictions from the Intergovernmental Panel on Climate Change (IPCC) suggest that fresh water supplies are likely to be depleted in some parts of Africa. As a result of climate change, lands will become drier, with less rainfall, affecting crop yields and making livestock farming impossible. In this possible scenario the water required to slake the investors’ fields could be considerable [13]. Along this line, biofuels have been described as “one of the thirstiest products on the planet”. For example, to produce one liter of biodiesel from soya (soybeans) requires 9,100 liters of water. As for the production of bioethanol from corn or sugar cane there is a requirement of as much as 4,000 liters of water for one liter of bioethanol. Still, even those biofuels considered to be optimal for arid places require large amounts of water in order to grow [24].
3. How land grabs can exacerbate climate change
Climate change as defined by the IPCC refers to "... a statistically significant variation in either the mean state of the climate or in its variability... Climate change may be due to natural internal processes or external forcing to persistent anthropogenic changes in the composition of the atmosphere or in land use.” The atmospheric changes associated with this phenomenon can be observed at all spatial levels from local to regional to global. It affects average global surface temperatures and sea levels, soil moisture and local precipitation, among other variables [36]. Currently, human society practices are negatively influencing these variables and thus, exacerbating this atmospheric phenomenon. Practices such as fuel burning and deforestation for agricultural purposes can have great influence in the world’s climates.
As referenced in Cotula et. al (2009), 80% of the global farmland is located in Africa and South America [37]. Most of these areas are either tropical rainforests, protected natural regions or are already used for shifting cultivation or grazing of animals [38]. However, they represent the most suitable regions for land deal investments. But the conversion of tropical forests to crop land, (mostly monocrops) come as an inevitable threat to the region’s biodiversity, carbon stocks and water resources [6]. Tropical forests do not only serve as reservoirs, sinks, and sources of carbon in the world, but also provide several ecosystem services that have impacts on a region’s climate. Among these services are the maintenance of elevated soil moisture and surface air humidity, reduction of sunlight penetration, weaker near-surface winds and the inhibition of anaerobic soil conditions [39]. This environmental arrangement is responsible for the rich biodiversity of tropical ecosystems [40]. However, as tropical landscapes are converted to agricultural and pasture areas, the productivity of this soil decreases as less rainfall, associated with changes in the solar radiation partitioning, is observed [39].
Many studies have demonstrated that changes in land surfaces (such as land clearing for agriculture) can influence both local and regional climates and can even have major impacts on climates in distant parts of the Earth [36]. For example, the Amazon Basin landscape is well known for having a direct influence in the flux and exchange of moisture into the atmosphere, regional convection, and hence regional rainfall. However, recent works have determined that the changes in the forest cover of the region have consequences on climates of distant places. The Sahelian drought associated with the destruction of regional vegetation [36] serves as another example of the relationship between changes in land cover and distant climates. In this sense, land deals can be considered major drivers of ecological impacts at both local and global scales. Such impacts can affect the ecosystem services that sustain human livelihoods as conversion of tropical forests to pastures takes place globally.
4. Food security under climate change
Food security defined by the United Nation’s FAO is “a situation that exists when all people, at all times, have physical, social, and economic access to sufficient, safe, and nutritious food that meets their dietary needs and food preferences for an active healthy life” [40]. The definition encompasses four important dimensions of food supplies; -food availability, stability of food supplies, access to food, and utilization of food - all of which are closely linked with impacts of climate change. First, food availability refers to whether or not the agricultural productivity of a region can satisfy food demand in that region. Second, food stability is an indication of how consistently the supply meets that demand. Third, access to food literally means the ability of individuals to buy proper food resources for their dietary needs. Lastly, utilization of food references how well individuals can consume food resources without undue concern for quality and safety of food [41].
Climate change affects almost every aspect of human society and natural environment, especially production of agriculture and food in multiple ways. Since many agricultural regions in the world have already suffered from extended drought and abrupt flood induced by global climate change, weather and climate variability will possibly change conditions of land suitability and agricultural productions [41]. Although temperate regions and higher latitude zones may get benefits of agricultural productivity by increasing temperature due to climate change, negative effects such as heavy rainfall, drought, and increased evapotranspiration on other regions (e.g., rain forest, semi arid region, and Mediterranean region) may hinder food availability in general [42].
Many predictions indicate that global and regional weather fluctuations and extreme weather events are expected to increase in frequency and intensity [43]. Because of the weather fluctuations, crop yields and local food supplies will also fluctuate and thus food stability and security could be adversely affected [41]. For example, extreme weather events like typhoons, hailstorms, and droughts will bring failure of crop yields. Specifically, sub-Saharan Africa and parts of south Asia, where most of high climate variable and arable lands are located, will be exposed to the highest instability of crops and livestock production [44]. Although the FAO predicted that access to food will be getting better in the long term based on falling food prices and increasing income level [45], this prediction might not consider the effects of global climate change that can possibly deteriorate the progress of food accessibility. Thus, if the situations - food prices, amount of crop yields, and supplies - of world food markets change under certain weather events, the ability to access food would also be changed as the recent food crisis in 2007 and 2008 suggests. In addition, the IPCC recently reported that increasing temperature will increase incident of more food poisoning, specifically in temperate areas, and cause food and water-borne diseases [43]. This means that individuals will need to more cautiously select and consume their foods. Thus food utilization, the last key dimension of food security, will also be affected by climate change.
All the key dimensions of food security induced by climate change consequently affect land deals in terms of both “host” and “investor” countries. Many host countries already face food shortages and difficulty to access food within local areas where land deals take place. Since land has shifted to foreign buyers, local communities cannot utilize their immediately surrounding land to produce food [13]. Many foreign investor countries, however, may take advantages of all dimensions of food security such as food availability, stability, accessibility, and utilization. Host countries are willing to sell their land in order to take advantage of short-term economic growth opportunities, due to the large-scale nature of land acquisition by investors. [37]. This tends to increase and accelerate land grabs in developing countries overall. Therefore climate change causes food insecurity in a way that changes temperature and precipitation in the first place and then food insecurity brings us more land grab to mitigate food shortages. Those three elements - climate change, food security, and land grab - are interconnected and, unfortunately, are detriment to each other.
5. Vicious circle among climate change, food security, and land grab
In the previous sections of the chapter, each two of three elements (i.e., food security and land grab, land grab and climate change, and climate change and food security) have been investigated through literature reviews in relation to climate change, food security, bio-fuels, and land grab. Explanations gained by reviewing relationships between each two elements, however, do not efficiently reveal the causal relationship among the elements and how closely coupled they are with each other. In this section, we attempt to describe the causal relationships among them in terms of a vicious circle framework.
Causal relationships among climate change, food security, and land grab make current situation worse in Global South, where people already have been suffering from food shortage and severe weather events, and increase vulnerability to climate change. Each of three elements adversely affects people in Global South in different ways that particularly threaten their livelihood, safety, and health. As discussed in the previous sections many other factors influence each of the three phenomena. For instance, land grab did not evolved due to food insecurity alone but growing global population, green energy demand, economic growth, and political reason [9]. Climate change and food security also have many reasons other than the factors in the Figure 1, however, since climate change, food security, and land grab in the circle are closely coupled, each of three elements will be treated as main driving forces in the vicious circle framework.
Figure 1 shows a vicious circle of climate change, food security, and land grab that is proposed by this chapter based on the review of relevant studies. As noted previously, climate change is likely to affect food security by increasing extreme weather events (e.g. extended drought, frequent and severe flood, cyclones, and hailstorms) which change land suitability for food production. In addition, demands to reduce carbon dioxide and other greenhouse gases, increased by human activities, lead the international society to seek alternative energy sources, biofuels and agrofuels thus esteemed as alternative energy sources that produce less CO2 and greenhouse gases. However, enormous amount of crops and crop fields are required to produce alternative green energy [24]. Since climate change is, again, a common driving force of increasing severe weather events and green energy demands, it degrades food security and increases demand of land grabs in general.
Figure 1.
Vicious circle of climate change, food security, and land grab
Along with food security and biofuels, there are many other underlying driving forces that accelerate land grabs such as demographic, economic, technological, political, institutional, cultural, and sociopolitical factors [9]. For example, world population has been increasing about 34% for 2 decades by 2007 and will keep increasing until 2050 under the medium scenario projection of the United Nations [46]. This means that the average amount of land per person will keep decreasing and population disparity at the global scale will consequently increase cross-national land deals [9]. The global economy also acts on land deals when agriculture attracts as an investment opportunity. At the same time, land grab exacerbates local food insecurity; because most of the regions, where land deals take place, have already been experiencing famine for a long time, even if the regions themselves have plenty of fertile lands.
The influence of land grabs to climate change significantly increases with deforestation in tropical rainforests where protected natural areas are also located [38]. Deforestation itself, particularly in tropical rainforest, has an adverse effect on reducing carbon dioxide and greenhouse gases through the process of photosynthesis. For example, some studies show that large amount of trees cleared for palm oil crop field can actually hold up to 150 years of carbon savings, and biofuels, which are initially proposed to decrease carbon dioxide and greenhouse gases, also negatively affect climate change by increasing CO2 and greenhouse gases [24].
Analysis of causal relationship among climate change, food security, and land grab confirms existence of a vicious circle that exacerbates vulnerability of poor and small farmers to climate change, and the safety and health of the Global South. Therefore it is important that efforts should be dedicated to disconnect each element of vicious circle or, if it is possible, focused on changing vicious circle into virtuous circle, since climate change, food security, and land grab have already threatened people there.
6. Discussion
Studies have shown that global land deals have increased dramatically in recent years, especially during the food crisis of 2007 and 2008. Some countries that need to guarantee food security and biofuels production as a strategy to cope with impacts of climate change and some other factors (i.e., demographic and economic factors) increased a scale of land deals in Global South. Consequently land deals have increased possibility of the climate change impacts by increasing deforestation. Deepening climate change once again can exacerbate food security and increases biofuels demands. This implies that the relationships between land grabs, climate change, and food security make vicious circle. However, it is not easy to approach for solutions from climate change perspective to ameliorate the vicious circle, while it is relatively easy to approach solutions from land grabs and food security perspective. That is because land grabs and food security are specific issues compared to the climate change discourse - one of the most complex issues of our day. This part of the chapter thus approaches to deal with land grabs and food security issues to dismantle the vicious circle.
As illustrated in Figure 1, climate change, food security, and land grabs are connected, and each element has harmful effects to the one next to it in a predominantly counter clockwise direction. This is why we named the framework as the vicious circle and it has causal relationship among elements. Although climate change, food security and land grabs are the main subjects of our conceptual model, they do not stand alone (see in the boxes of Figure 1). Some of them affect reverse direction (e.g. land grab causes local food insecurity). However, the three elements are core sources of making vicious circle to people in Global South. It is important to dismantle and neutralize this circle, as each element is primarily responsible for the damage done to the next. There are both short-term and long-term policies or strategies that may accomplish this. For example, long-term strategies should be suggested for climate change issues. However, this chapter will not touch any policies and strategies on mitigation, adaptation, and vulnerability directly to climate change, since nature of climate change cannot shortly be improved by any efforts due to the complexity of the climate change itself. Instead, policies for land grab and food security (include biofuels) can be discussed as short-term policies.
Figure 2.
Loosely-coupled and disconnected by applying alternative policies over time
First, land grab can be reduced and controlled relatively in short time period, if countries targeted for land deals recognize the outcomes and tradeoffs of these deals (e.g. local food insecurity) and regulate it through alliance with countries in similar condition. In fact, some host countries are already considering alternative policies such as “strict limitations on foreign ownership of land; limitations on farm size/land ownership; limitations on the farm acreage dedicated to a single crop or livestock production (soy monoculture, for example); limitations on the total national acreage devoted to a single crop or livestock production, and; limitations on the strict controls on foreign investment in food and agriculture.” [17]. Second, there might be alternatives for food security that may lead to reduce land grabs. Governments depending on imported food could help domestic farmers to increase production by agronomic research. For instance, farmers in food importing countries switch crop varieties and/or develop new varieties better able to produce in terms of volume, and develop biotechnology as well. Third, as a direct competitor to food production and another driving force of the land deals the biofuel production should be alternated by technologically innovative new energy sources [47], since production of biofuels does not really help reduce greenhouse gases, but increases land grab and worsen climate change. Countries seeking green and new alternative energy sources invest in, hydrogen fuel, wind power, solar power, and tidal power, for instance.
Innovative approaches to increase food and energy security suggested above will likely reduce land grabs. Each of the efforts suggested above will keep reducing issues along the line of vicious circle. Even though only a few short-term policies were suggested here, there might be more solutions and efforts to remove many issues in the vicious circle of climate change, food security, and land grab over time. Therefore, the short-term policies connected with long-term policies to climate change may pragmatically trigger a transformation of the vicious circle into a more virtuous circle or at least weaken the connection between each two of the elements (Figure 2).
7. Conclusion
There are many studies on the relationship between climate change and food security, food security/biofuels and land grab, and land grab and climate change. However, isolating and addressing one pair of issues at a time masks what is really going on in terms of the vicious circle which keeps each element in the circle locked into a downward spiral. The people in the Global South, especially in Africa, are thus more vulnerable to conditions out of their control. This chapter examined the relationship between climate change, food security/biofuels, and land grab as a concept of the vicious circle. To reduce problems in the vicious circle, first of all, each pairs were examined to figure out issues between pairs respectively. Second, causal relations among the elements were shown and explained as the vicious circle. Lastly, based on the examination, disconnecting solutions, in terms of policies, were briefly suggested.
Despite many other factors, this chapter has only focused on the three elements; climate change, food security, and land grab, as the vicious circle. This does not mean that policies suggested here may solve all the issues on climate change, food security, and land grab, but solve or weaken some issues of them. Furthermore, policies may trigger a disconnecting of the links in the vicious circle or transform the vicious circle into a virtuous circle with other possible policy efforts, and can be starting point of reducing vulnerability of people in Global South.
Acknowledgments
The authors would like to thank the editor Netra Chhetri who gave us valuable advice and opportunity to write a chapter. We also thank Helme Castro and Evan Palmer for their careful and quick proofreading of our manuscripts.
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Introduction",level:"1"},{id:"sec_2",title:"2. Global land grabs",level:"1"},{id:"sec_2_2",title:"2.1. Land grabs undermine food security",level:"2"},{id:"sec_3_2",title:"2.2. The “food and biofuels conflict”",level:"2"},{id:"sec_4_2",title:"2.3. Seeking land and water",level:"2"},{id:"sec_6",title:"3. How land grabs can exacerbate climate change",level:"1"},{id:"sec_7",title:"4. Food security under climate change",level:"1"},{id:"sec_8",title:"5. Vicious circle among climate change, food security, and land grab",level:"1"},{id:"sec_9",title:"6. Discussion",level:"1"},{id:"sec_10",title:"7. Conclusion",level:"1"},{id:"sec_11",title:"Acknowledgments",level:"1"}],chapterReferences:[{id:"B1",body:'DamerowH.2010International Politics, web lecture note. Available: http://faculty.ucc.edu/egh-damerow/global_south.htm.accessed 18 June 2012).\n\t\t\t'},{id:"B2",body:'LutzW.SamirK. C.Dimensions of global population projections: what do we know about future population trends and structures? 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1. Introduction
The first sheep were brought to the Magallanes region from Chiloe in 1845 as a food source for the region’s new human settlements. The Magallanes governor encouraged the development of a larger sheep industry, which began in January 1877 with the arrival of the first Cheviot sheep from the Falkland Islands (Malvinas). Progress in Magallanes throughout the last 145 years has transformed the region into the most important sheep farming area of Chile via the development of both, meat and wool production. In the last 20 years, improvements have been realized through a strategic use of management techniques (strategic feeding, grazing, soil fertility, water supply, crossbreeding and brush control) and new technologies (plow machinery, direct drilling, artificial insemination, embryo transfer, dietary supplement formulation, satellite imagery, silage baling, and electric fence) that have enhanced both, process efficiency and product quality, forward to sustainability management.
To understand the different aspects of sheep farming and its development within the socioeconomic and environmental context of the Magallanes region, this chapter covers topics including location, climatic conditions and main characteristics of the livestock use area, common grazing management systems, locally-adapted fodder crops, artificial insemination, the main breeds (Corriedale, Merino mainly and meat crossbreed), breeding, lamb meat quality under different grazing regimes, wool management, lactation curve and cheese production, animal welfare, sheep-wildlife interactions, and rural tourism.
2. Geographical area and weather
The Magallanes region corresponds to an extensive territory located in the extreme south of Chile and the South American continent, encompassing the meridional section of Patagonia and the occidental part of the Isla Grande de Tierra del Fuego, and the numerous archipelagos that make up a strip adjacent to both parts, ending in the south with the Cape Horn archipelago. The region extends from 48° 40′ to 56° 30′ south latitude (the greatest latitudinal amplitude in Chile), covering an area of 132,033.5 km2 (Figure 1A) [1]. The region is characterized by a marked physical contrast, generating different geological, orographic and climatic zones, which determine high amplitude in terms of vegetation types [3]. Likewise, there is a pronounced gradient of precipitation from west to east, going from more than 5.000 to less than 200 mm per year respectively [4, 5]. These characteristics make it evident that, in Magallanes, the territory of the eastern section is the most suitable for human life, and that is where the cattle activity has been established since 1870 [1, 6].
Figure 1.
Cartographies of the area of livestock use in the Magellan region. A: General location. B: Livestock use according to administrative division. C: Elevation ranges. Source: Own elaboration from ASTER GDEM digital elevation model. D: isohyets (mm·year−1) and isotherms (annual mean ° C) (prepared by author based in Ref. [2]).
The livestock use area is located mainly in the eastern section of the Magallanes region, extending between 50° 36′ and 55° 19′ south latitude and 67° 2 ‘and 73° 47’ west longitude, covering a surface area of 35,962.6 km2 distributed mainly in the provinces of Magallanes, Tierra del Fuego and Ultima Esperanza (15,577.9, 13,502.2 and 6,559.9 km2 respectively). With less representativeness and in the southernmost distribution lies the livestock territory of the Chilean Antarctic province with 322.5 km2(Figure 1B) [7]. The livestock use area can be divided into three provinces from north to south (the area corresponding to the Chilean Antarctic province is not considered in this analysis). The first section located in the Ultima Esperanza province presents spatial and topographic patterns different from the other sections (Magallanes and Tierra del Fuego), corresponding mainly to a transition strip between mountain ranges and the eastern plains, characterized by plateau sectors crossed by mountain chains with heights that rarely exceed 1000 masl (Figure 1B). The Magallanes and Tierra del Fuego sections present similar characteristics, beginning with a western sub-Andean transition strip that gives way to extensive eastern plains, corresponding to mainly flat territories, with low elevations and moderate undulations (Figure 1C) [3].
According to [8], from a climatic point of view, based on Koppen classification, this area can be defined as a trans-Andean climate with steppe degeneration in its western fringe and a cold steppe climate in the eastern plains sector. In the former, we can find annual average temperatures ranging from 2.6 to 6.6° C, while in the cold steppe climate the annual average temperatures can range between 4 and 7.4°C (Figure 1D) [2, 8]. On the other hand, the area of interest is located in the sotavento zone (east) of the Andean Patagonian mountain range, which despite presenting spatial discontinuities in its southern distribution, is the main geographical feature of the region and forms an orographic barrier that generates local climatic changes [5, 9]. This is how rainfall in the livestock use area can drop from approximately 600 mm to less than 200 mm per year in the direction of the Atlantic coast in the sections of Magallanes and Tierra del Fuego, while in Ultima Esperanza the rainfall ranges from 1,000 mm to 300 mm in the same direction W-E (Figure 1D) [2].
The marked variation in rainfall in the area of livestock use is reflected in the present vegetation, which could be categorized into three ecoregions: the Patagonian steppe, the deciduous Magellan forest and evergreen forest, but the latter have a small participation. The dominates the sub-Andean region, is present in the three provinces of the area of livestock use, characterized by associations of Nothofagus pumilio (lenga) and also including forests of Nothofagus antarctica (ñirre) and associations with Nothofagus betuloides (coihue de Magallanes) in the most humid sectors [3]. It is worth mentioning that in this ecoregion and specifically in the area of livestock use, there are extensive areas of forests that were formerly burned with the purpose of enabling land for livestock [10] and that today are known as naturalized grasslands. Dominating the area of the eastern plains, we find the Patagonian steppe, defined as a hard grass community without the presence of trees [8]. The characteristic specie of this ecoregion in Magallanes is the tussock coiron (Festuca gracillima), which may be present to different degrees of dominance or even absent in some cases. In this ecoregion, three large types of communities can be distinguished: a) natural grasslands, made up of coiron grasslands, vegas (mesic grasslands) and saline grasslands, b) scrublands, represented mainly by Chilliotrichium diffusum (romerillo) and other species less distributed and c) heaths (sub-shrubs), where Empetrum rubrum (murtilla) stands out [11]. It is important to highlight that 91.8% (24,434.2 km2) of the Patagonian steppe area present in Chile is located in the livestock use area of the Magallanes region and the Chilean Antarctic [11].
3. Grazing systems in Patagonian grasslands
The soils in the grazing fields in the region de Magallanes in Southern Chile are glacial and fluvio-glacial, with sandy-loam and loam-clay-sandy textures and a shallow surface soil horizon with mid to high organic matter content. The soils classification is dominated mainly for mollisols, but also histosols, inceptisols, espodosols and aridisols. Mineralization is very slow, implying severe nitrogen deficiency, also phosphorus and sulfur are limiting factors; pH values range from west to east from less than 4.8 rising to 7.7 where topography favors humidity and the accumulation of salts [11]. The photoperiod in summer is 12–14 hours/day, favorable for most long-day grasses. Dominant vegetation includes 32.7% of native shrubs and tussock grasses (Chiliotrichium diffusum – Festuca gracillima); 26.9% of tussock and naturalized grasslands (Festuca spp, Poa spp); 12.2% of dense shrubs (Ch. diffusum-Empetrum rubrum) and 16.5% forests (Nothofagus pumilio). Sown and improved pastures (T. repens; D. glomerata; Festuca spp) comprise 2.5% of the total area, and about 5% is scattered highly productive humid areas or wetlands (also called vegas) of glacial and morrenic origin (graminoids). The mean nutritive value of native grasslands is low (roughly less than 9% protein and 8.75 MJ EM/kg DM) but selectivity and seasonal variations allow an extensive grazing system sustaining at present over 1,570,000 sheep [12] and 100,000 cattle [7].
3.1 Patagonian grazing systems
Sub-Antarctic rangelands were originally dominated by dense high tussocks (Festuca sp.) and less palatable shrubs. However, after the onset of the sheep industry, stock numbers rose to about 3 million by mid-20th century [13] and the grazing vegetation community shifted, first towards short tussocks and an inter-tussock cover of dense, low stature grasses and geofites, and later towards growing patches of invaders such as Taraxacum sp., Agrostis sp., Aira sp. or Hieracium sp. and even bare soil following the humidity gradient. In contrast, wetlands are dominated by more palatable species [14, 15] with higher growth rates in comparison to the sites dominated by F. gracillima [16].
The extensive grazing management in Patagonia (Magallanes region in Chile and Southern Patagonia in Argentina) is defined as a seasonal continuous grazing system, with summer set-stocking on paddocks above 150 m of altitude. Early on, grazing was adapted for wool production, a productive system with lower nutritional demand. The productive system has since shifted towards meat production, increasing the nutritional requirements of sheep due to the pregnant ewe and lamb raising [17]. Considering an estimation of dry matter consumption by an ewe of 50 kg live weight raising one lamb is around 650 kg DM year−1.
The Sub-Antarctic rangelands (also called coironales) have an herbage mass production between 33 and 1439 kg DM ha−1 year−1 (depending on edaphoclimatic condition and grazing management) and are dominated by F. gracillima [16], a low palatability tussock species with low nutritional value that does not fulfill the minimum requirements of energy and protein for sheep maintenance and growth [18]. By comparison, wetlands or valley greens in Magallanes represent just 5% of the total productive surface with herbage mass production that ranges from 500 kg DM to 11,000 kg DM ha year−1 [16, 19]. These differences are due to the wetland’s intrinsic properties [14, 20] and poor farm organization to do not separately fence wetlands from the less productive sites (rangelands dominated by F. gracillima), leading to overgrazing due to continuous use, and increasing the heterogeneity within and between paddocks due to selective grazing [21], increasing the risks of soil erosion and ecosystem degradation for both rangelands and wetlands. Therefore, due to their difference in growth potential, rangelands dominated by F. gracillima need to be managed from an extensive management approach whereas wetlands are more adapted to an intensive use [17].
3.1.1 Continuous grazing system
Extensive pasture size and large herd numbers (thousands of animals), combined with the climatic conditions and cultural traditions, have led to seasonal continuous grazing being the most common livestock production management approach. This extensive management system is characterized by large paddocks of hundreds of hectares, designed to separate stock categories rather than to target defoliation periods. The defoliation period is determined by season, sheep physiological periods and location of the grazing sites. In sub-Antarctic rangeland, snow cover determines when and where herds graze. The grazing year is split in two periods, with summer grazing from December to May in wetlands or sites with altitudes of 150 m above sea level or greater. Winter grazing occurs from May to December in lower altitude sites with a more favorable temperature range during the coldest months [17, 22]. Winter grazing generally overlaps with lactation and postpartum periods [22, 23].
Even though the disadvantages of continuous grazing in highly productive livestock systems are clear, in low-producing rangelands, the disadvantages are more ambiguous. It has been indicated in medium and long-term experiments [24] continuous grazing with the correct stocking rate, calculated based on herbage mass production, is an effective way to control desertification and achieve good animal performance [24, 25]. However, it is recognized that continuous grazing can increase heterogeneity [25] and weed invasion [26] on overgrazed sites.
Sheep actively select preferred species based on plant phenology (tender shoots and new regrowth, flowers and fruits) thus, in continuous grazing management, sheep overgraze the more palatable material, under grazing or leaving untouched older shoots. Recommended grazing practices imply an even, controlled defoliation height, followed by a specific regrowth period. The latter is supported by physiological plant research performed in several species [27, 28, 29, 30, 31], suggesting that, independent of the grazing system or ecosystem evaluated, vegetative species, particularly forage species, depend on energy reserves to regrow following defoliation [32] and to survive after drought periods [33]. Thus, selectivity must be avoided through careful estimation of grazing pressure. This requires more, smaller paddocks of similar vegetative communities, and strict control of grazing frequency. Animal nutrition must be considered, since enforcing the consumption of low nutritive value material may not be tolerated by younger or pregnant sheep. Modifying the traditional system is a major task implying qualitative and quantitative changes in both labor and mind set.
3.1.2 Rotational grazing
For rotational grazing to be performed, it is necessary to improve farm organization and increase the number of paddocks, separating different vegetative communities, such as wetlands, rangeland and forests, to avoid the negative effects of seasonal continuous grazing [21]. Several types of rotational grazing have been proposed for rangeland grazing management, however, as sheep reproductive phenology has to be considered [23], two of them could be applied in the Magallanes region: 1) rotational deferred grazing; 2) traditional rotational grazing with a high animal density [17, 24, 25].
Rotational deferred grazing: In this system, each paddock is rested for a full year at some point in a multi-year rotation to allow species recovery and reseeding [24] and to recover ecosystem resilience after years of defoliation [25]. There are no clear results in animal performance when rotational deferred grazing is compared to continuous grazing [24]. Furthermore, [25] indicated that in Moy Aike Chico, there were no important differences between a rotational deferred grazing system and continuous grazing in terms of animal production.
Traditional rotational grazing: There have been a few examples in the region with different frequencies and intensities. However, high intensity grazing is not recommended in rangeland settings due to the diminishment in animal performance and the low durability of the rangeland [24]. Grazing with low intensity and short duration at an experimental level (Experimental station Leleque, Southern Patagonia) showed an improvement in animal performance, however, the low growth rates during winter together with a low precipitation, mains factors that limit the herbage growth in Patagonia, meant the resting periods would not be long enough for forage species to recover [25]. There is not enough evidence of the benefits of rotational grazing over continuous grazing in ecosystems with low potential growth under a proper stocking rate [24, 25, 34]. However, rotational grazing showed benefits over continuous grazing in sites with high potential growth such as in sites with higher rainfall or wetlands.
In 2004 a rotational experiment with lambs was carried out on a wetland in Tierra del Fuego. The wetland was excluded from the rest of the paddock and regenerated by direct drilling (zero tillage) with a mix of species including Lolium perenne, Festuca arundinacea, Dactylis glomerata, Trifolium repens and Plantago lanceolata at a seeding rate of 28 kg ha−1 of grasses and 8 kg ha−1 of broadleaf species. Nitrogen, phosphorus, potassium and sulfur were applied at 46–46 – 22 – 22 kg ha−1, respectively. The original botanical composition evaluation identified Azorella trifurcata, a creeping plant without livestock value, as the dominant species. The natural grassland reported an average gross protein value of 40 g kg−1 in. After four seasons, the trend of dry matter production was analyzed. In the first year, approximately 1035 kg DM ha−1 were produced, and the annual average for the next three years was no more than 3600 kg DM ha−1 while the natural grassland in the exclusion zone (5 hectares) produced up to 700 DM kg ha−1 annually during the four seasons. In the last season, lamb liveweight gain after one month of rotational grazing (stocking density of 80 lambs ha−1) was 2.05 kg per lamb moth−1, significantly higher than the gains in the traditional grazing system (1.39 kg per lamb and a stock density of 2 lambs ha−1).
3.2 Future perspective
Modification of the traditional management is imperative to stop the depletion of the ecosystem functioning caused by sheep overgrazing in the Magallanes region. Ecosystem parameters such as vegetation, soil and water have to be considered to reach a sustainable productive system. Remote sensing technologies are an excellent tool for planning and evaluating changes in paddock grazing duration and timing, where University of Magallanes has developed this technology with use of satellite image in the agricultural area of the region from 2003. Also, the study of soil microbiology is an incipient area in development and could be an excellent assistance for soil fertility and grassland production. Efforts to shift the traditional paradigm from a sole focus on animal condition and performance to one that includes ecosystem functioning exist [35]. However, controlled experiments have to be performed to determine the necessary resting periods for the recovery of the rangeland and wetland vegetation, soil and water parameters.
4. Fodder crop
Livestock production in Magallanes depends on rangelands as the main source of food [36]. However, rangeland vegetation alone cannot meet sheep nutritional requirements, especially during peak nutritional demand (for example, the third trimester of pregnancy) [37]. Although wetland areas can provide food in quantity and quality, these are in a state of progressive degradation or are not capable of sustaining an acceptable production throughout the year due to erratic forage production. Since the beginning of sheep production in the region, farmers have seen the need to establish forage crops as a hay source, during critical physiological periods and harsh weather, or for grazing with the objective of increasing lamb weights before slaughter.
Establishment and development of sheep farming began in the Magallanes region during the second half of the 19th century. Large land concessions by the State and investment from private companies allowed the growth of the sector in the southernmost region of Chile [36]. Establishment of forage crops should be considered within its historical context.
In 1976, the Magallanes region had around 248,504.6 ha of sown grasslands, which could be divided between annual crops and permanent grasslands [38]. Ten years later, there were between 104,878 ha [39] and 194,185 ha [40], which were based on the use of forage mixtures such as cocksfoot (Dactilys glomerata), common velvetgrass (Holcus lanatus), white clover (Trifolium repens), monophytic grasslands of common velvetgrass, alfalfa (Medicago sativa), Festuca rubra and Agropyron elongatum. Although the Tierra del Fuego Livestock Society planted 10,000 ha year−1, today the vast majority are missing or in a state of degradation [41].
Current numbers indicate that there are no more than 6,039.2 ha of forage crops, of which the vast majority is alfalfa. However, [42], estimates that there are currently around 9,800 ha of alfalfa in the region. This is because state subsidy programs that begun in 2004 have allowed ranchers to establish fodder crops. Sowing grasslands is a necessity on the part of the agricultural sector and the area devoted to forage crops has been increasing. Although there is a wide range of species and cultivars on the market, only a few are able to establish themselves and produce desired yields due to edaphoclimatic conditions.
Among the most adaptable species are oats (Avena sativa) as the main annual crop and alfalfa and mixed meadows (mixes of cocksfoot -Dactylis glomerata-, tall fescue -Festuca arundinacea- and white clover –Trifolium repens) as permanent meadows. There are two different establishment methods for perennial plantings in Magallanes: a) traditional tillage; b) zero tillage by direct drilling. This last method is unique, but its effectiveness depends on site conditions such as species competition, soil humidity and soil depth. Some examples of typical direct drilling in the region are alfalfa on tussock steppe (without use of herbicide) and mix of grasses with white clover on meadows.
Rainfall during the growing season strongly influences yields since regional production is based on dryland systems with no irrigation, but there is an incipient advanced irrigation technologies as center pivot in Tierra del Fuego. The current varieties of oats have yields that can range between 5,000 and 10,000 kg DM ha−1 [43, 44]. Other annual crops such as hybrid rye can produce between 8,000–12,000 kg DM ha−1 [45]. Cocksfoot can yield from 3,000 to 7,000 kg DM−1 in the third year from the establishment, while tall fescue can produce 4,000–6,000 kg DM ha−1.
Without a doubt, alfalfa is the main forage crop in the Magallanes region. This species is preferred because of its ability to establish itself in the vast majority of the soils and climatic districts of Magallanes (Figure 2). Fall dormancy level 3–4 varieties capable of going into dormancy in the autumn-winter months are used. At least three years are required for the crop to enter full production, increasing forage production from 400 kg DM ha−1 [46] in the first year to a potential of 12,000 kg DM ha−1 [47].
Figure 2.
Fodder crop of Alfalfa in Torres del Paine, Magallanes region (Image by Jorge Ivelic-Sáez).
Management of forage crops in Magallanes is based, normally, on cutting for hay or silage during December and January. In March and April, following regrowth, fields are grazed in order to increase the weight of lambs before slaughter.
5. Artificial insemination
Farm productivity depends on each sheep producing at least one lamb each year. The use of natural service during the breeding period is the most common practice in commercial Magallanes farms. However, since the 1970s, artificial insemination (AI) has been part of the production system, especially in stud farms, in order to accelerate the genetic progress and the production of flock replacements (males and females).
5.1 Artificial insemination: a productive tool
AI has been used mainly in genetic and selection programs, in order to improve the commercial traits of interest [48]. For dual purpose breeds such as Corriedale, increasing fleece weight, reducing fiber diameter, and augmenting lamb weight at weaning are normally the traits to be improved via introduction of animals with a higher genetic value [49]. In Merino animals, fleece weight and reduced fiber diameters are the main selection traits. Among the different alternatives, intracervical AI using fresh semen is the most widely used AI technique.
5.1.1 Preparing the animals for artificial insemination with fresh semen
Selection of males is the first step in AI programs. Regardless of the origin (self-produced or acquired from a sheep stud farm), rams will be selected according to their phenotypic and productive characteristics. Genital tract soundness, evaluation for brucellosis (Brucella ovis), and conformation of legs, hoofs, and mouth, are normally checked by the farmer at least one month before the onset of the reproduction season. A good body condition and body weight will also be checked prior to the AI program as it influences the reproductive efficiency of animals [50], particularly prolificacy in Magallanes [51]. Similarly, females selected as recipients will be checked for body condition and any health issues, paying special attention to age, teeth, mouth and udder conformation and soundness.
5.1.2 Estrus synchronization protocols
Different estrus synchronization protocols are used in Magallanes selected based on factors such as labor, cost and efficiency. Although some producers may use the natural estrus, two options of synchronization are commonly utilized. The first one is the use of prostaglandin analogs in one or 2 doses, separated by 11–12 days [52]. The second one uses progestogens in the form of sponge pessaries or CIDR devised, used for 11 to 14 days available in the market with estrus concentration of 90% of the animal in 81 h after sponge withdrawal [53]. A protocol using equine chorionic gonadotrophin (eCG) hormone at the time of CIDR withdrawal is normally used to improve ovulation rate and fertility [54].
5.1.3 Artificial insemination facilities in Patagonia
Due to cold weather conditions, the use of indoor facilities is highly recommended. The basic infrastructure is a room for semen extraction, with a head stock for a female in heat, and a lower area for the personnel to have a better access to the ram penis. Lubricant gel, warmed water and artificial vagina for practicing, are the basics for obtaining semen. After semen collection, quality evaluation (e.g., volume, concentration, motility, etc.) and dilution takes place. This occurs in the lab area, where room temperature is maintained between 20 and 25°C. Access to the sheep in heat is through a window located at the height of the vulva, with the operator standing in an insemination pit in the floor of the lab and barn, and the ewes will be transported in a trolley with wheels on rails.
5.1.4 Fresh semen artificial insemination
Regardless of the synchronization protocol, the use of teaser rams helps in the identification of ewes in heat. Teaser rams are painted with a mix of edible oil and colored soil in a ratio of 2 liters of oil per 1 kg of soil. The use of a harness with a crayon has been previously evaluated, however; special attention must be paid to crayon selection, since temperatures below 0°C, which are normally observed during the winter, interfere with a good painting of ewes in heat. The mix with oil must follow a soil color gradient, starting with light colors and finishing with dark ones (e.g. yellow, red, blue and finally black) as this allows the identification of animals in different reproductive cycles, which normally lasts between 14 to 17 days.
Females are normally taken into the yards once a day, early in the morning. Those ewes showing a clear rump mark are separated, while those not presenting heat returns to the paddock with the teaser rams. Ewes in heat are artificially inseminated in the afternoon. However, in order to increase pregnancy rates, two checks in the day are recommended, early in the morning and in the afternoon, with ewes being artificially inseminated in the afternoon and the following morning, respectively. Every two or three days, the painting of the teaser rams is redone.
Fertility rates between 60 and 70% can be achieved with this method [48]. During AI the ear tag of each of the ewes is recorded, in addition to ram number and day and time of AI. After AI, ewes are maintained in a quiet place, with access to food and water, before being taken to their paddock. The use of dogs during all process is normally restricted in order to reduce stress in the animals, which could affect fertility.
5.1.5 Frozen semen artificial insemination
Sometimes, the farmer has the opportunity to import frozen semen from different countries (e.g., New Zealand and Australia due to their good sanitary status, similar to Magallanes). If this is the case, the use of intrauterine laparoscopic AI is the best course of action, with the use of eCG (200–300 IU) as a complementary management, to increase ovulation rate and the number of twins, with higher expected genetic potential. Fertility with frozen semen has been calculated to be over 70% [55].
5.2 Management concepts associated to artificial insemination
Good animal nutrition before and after AI reduces stress, and the farmer needs to consider forage quantity and quality, as well as access to water. Ultrasound pregnancy diagnosis is performed 90 days after AI, in order to check for fertility, but more importantly, to identify single- from twin-bearing ewes. Hence, the latter can be supplemented with a high protein (22%) concentrate to reduce lamb mortality at birth [18], which, under Magallanes environmental conditions, can range from 22 to 62%, being higher in twins [56]. All these managements contribute to increased AI success in Magallanes, making the system more productive and sustainable.
6. Breeding, breeds, and management of sheep production system in Magallanes
Since the second half of the 19th century, the establishment and development of sheep ranching began in the southernmost region of Chile, Magallanes. Large land concessions by the State, and an important commitment from private companies allow an accelerated growth of this industry, being sheep an intrinsic part of the local culture until today.
Natural rangelands in the world, which largely dominate the geography of Magallanes, are those areas used mainly for grazing because they cannot be cultivated. In these large rangelands, the grazing system is “extensive”, not only in the sense that it is carried out over large areas, but also because level of inputs, and management of animals is relatively low, with a stocking rate around 0.8 sheep equivalent ha−1.
6.1 Animal and natural resources
The sheep population in Chile is 2,037,516 heads and the 77.1% is located in Magallanes (1,571,056), the southern region of Chile [12]. In this area, sheep production is the most important, and almost the only agricultural industry. It has been developed for the last 145 years (Figure 3).
Figure 3.
Number of sheep in Chile and Magallanes region. Dots in red and blue lines counting data between VI to XII region and farms with higher than 60 sheep [7, 12, 13, 38, 39, 57].
Corriedale is the main breed and represents 55% of the regional stock, just as a purebreed. Some operations have introduced different Merinos, as Australian Merino, MPM (Multi Purpose Merino, developed by an Australian stud, and imported for some breeding seasons into Magallanes), 4 M (Marin Magellan Meat Merino, developed by Marin family in a big sheep operation, from MPM and other Merino lines, and registered officially as the first local purebreed), and most important in recent years the Dohne Merino, and crosses during the last three decades. Because of the increasing value of meat in the total income of sheep business, it is common to see terminal cross use, typically with Suffolk rams but also some Polled Dorset, Texel, and White Suffolk. The regional average weaning percent is below 80%.
Breeding season is in fall, and lambing in spring. The extensive management system with very low inputs, low human intervention, and changing annual climatic conditions leads to erratic results.
Land is owned by medium to large producers. The most common situation are flocks with over 4,000 sheep. The meat and wool market is well developed in Magallanes and strongly oriented to exportation. The region has the potential to increase sheep numbers by at least 30% based on increased production estimates from improving 600,000 ha. of rangeland [58].
6.1.1 Management
Sheep production has traditionally been dual purpose; producing wool and meat, with a carcass average weight for lamb increasing from 10.8 in 1987 to 14.1 in 2020, meanwhile the market is targeting 14 to 16 kg [35].
In this scenario, meat, which at one time in the past was considered a by-product of the wool-focused Magellan sheep industry, today drives the income of sheep ranching in the region. Furthermore, San Isidro Farm (Canepa family) in conjunction with INIA Kampenaike introduced three races of hair sheep (White Dorper, Dorper, Katahdin) in 2012 with a high meat performance.
Sheep operations are based on year-round grazing of private land, with incipient use of strategic supplementation. Most ranches own summer range and winter on separate range (Figure 4). Over half do pre-lambing shearing, and lambing is on pasture at springtime.
Figure 4.
Herding sheep from summer to winter range, Tierra del Fuego (Image by Oscar Strauch).
7. Meat quality
The Magallanes region is not only recognized for its natural parks, such as Torres del Paine, but also for the vast pastoral landscapes and extensive sheep farming developed in this unique environment. The main product is lamb meat, which is exported to different countries, predominately in Asia (China: 45%) and the EEC (Italy: 12%) [59].
Magallanes lamb meat is a grass-fed product that normally comes from young animals (4 to 5 months of age), with an average carcass weight of around 13 kg, raised on natural pastures and maintained, in general, with their mothers until mark time. This gives them a mix of milk and grass nutrition which results in a very interesting product quality. Studies developed by INIA (Agricultural Research Institute), have demonstrated that lamb meat from Magallanes has on average 21% protein content, and a total fat content of 6.4%, which is lower compared to other type of meats. When considering the intramuscular fat (2.5%) and cholesterol (53 mg/100 g), this product may be considered as lean. Tenderness is another remarkable attribute of Magallanes lamb meat, with Warner-Bratzler shear-force results of 1.75 kgf, which positions it as a very tender meat. In addition, it has a similar content for SFA (2900 mg/100 g) to other meats, but a higher PUFA content (628 mg/100 g), compared to some reports in beef. However, the n-6/n-3 ratios (1.3 mg / 100 g) and conjugated linoleic acid (CLA; 25 mg / 100 g) contents represent values that are considered good and desirable from a nutraceutical point of view [60].
7.1 The role of Magallanes lamb meat in human nutrition
The meat of lamb produced in Magallanes is characterized for having a high content of iron (Fe) and zinc (Zn). The average content of Fe for lamb meat in the three different areas of production in Magallanes is 3.9 mg/100 g of meat. This value is significantly higher compared to other meats (Table 1). Similar results are observed for Zn content which, with an average of 4.5 mg/100 g of meat, is superior to the Zn content described for other meats (Table 1).
Meat
Fe
Zn
Magallanes lamb
3.9
4.5
Foal
3.3
2.4
Lamb
2.3
2.4
Chicken
0.8
1.3
Beef
1.9
4.0
Pork
0.9
2.1
Table 1.
Iron and zinc levels in meat from different species (mg/100 g) [61, 62].
Iron is well known for its role in human health and disease, where deficiencies may result in anemia, leading to functional impairments, affecting cognitive development, immunity mechanisms, work capacity, learning ability, and are associated with increased rates of morbidity. Deficiencies during pregnancy may result in higher risk of sepsis, maternal mortality, perinatal mortality, and low birth weight [64]. According to the WHO [65], the iron requirements of 97.5% of individuals, in terms of absorbed iron, are higher in menstruating women (2.38 mg/day), 12–16 year-old girls and boys (2.02 and 1.92 mg/day, respectively), and lactating (1.31 mg/day) and pregnant woman (1.14 mg/day). Therefore, Magallanes meat lamb consumption is an excellent source for these groups to cover their daily iron requirements.
An adequate intake of zinc has critical impacts for human homeostasis, immune function, oxidative stress, apoptosis, and aging. A deficiency, even mild, may lead to arteriosclerosis and anemia [66]. The recommended daily dietary zinc requirement is estimated at 15 mg/day [67, 68]. The consumption of Magallanes lamb meat could certainly help cover this recommendation. In conclusion, the high content of iron and zinc, the low n-6/n-3 ratio and high CLA content, low cholesterol, and tenderness, make Magallanes lamb meat a healthy food with desirable organoleptic characteristics.
8. Wool production
Magallanes was an adequate location for extensive sheep production when wool was a commodity of worldwide importance. Historically, wool was bought in bulk directly on the farm through private deals, but since the 1980s the system has evolved to prices defined by proper conditioning and bale sampling for wool fineness (Table 2 and Figure 5).
Price, yield, and wool stock purchased by Standard Wool Cia. from 1998 to 2021 [63].
In these seasons, many farmers did not sell their wool production for low prices, because of the pandemic situation.
M.T. = metric tons.
Figure 5.
Net and clean wool purchased according to fleeces fibre diameter (season 2018/2019) [69].
Almost the entire wool crop is exported to a world market dominated by China. The wool exportation of Magallanes 50 years ago was 13,000 tons [70], but decreased to 5000 tons in the 2017 season [57]. Table 2 shows the price evolution to higher values while wool stocks have simultaneously trended down in recent years with a mean yield of 65% for Standard Wool Company [63] and Agropat1.
Industry trends towards lamb production and fine wools has changed traditional management from extensive grazing with the dominant Corriedale breed, focused on medium fineness wool production (24.5–31.5 μm and 4.0 kg fleece weight per ewe), to more intensive grazing systems based on dual purpose breeds, focused on lamb production and finer wools. Evaluation and breeding programs to meet shifting market demands have been proposed for different resources availability. In Magallanes there are some Corriedale studs grouped in the Corriedale Breeders Association: El Kark (Kroger family); America (Cardenas family); Jerónima (Vilicic family); Avelina (Menendez family); El Trébol (Maclean family); Tehuel Aike (Almonacid family); Chañarcillo (Gutierrez family); Las Vegas (Retamal family); Maria Isabel (Cavada family)2.
In Magallanes two new Merino crosses breeds have been registered in the past ten years: 4 M Merino (Marin Magellan Meat Merino – Tres Chorrillos farm by Marin family) and PRM (Patagonian Robertson Merino – Tres Hermanos farm by Robertson family), both aiming for finer wool (17–22 μm) and heavier lambs, while maintaining the hardiness of Corriedale. For another side, Dohne Merino has been introduced successfully in the region by Hugo Vera in 2004 (Josefina farm), and has resulted in higher profitability on some farms in comparison to traditional breeds [71]. Figure 5 show fleeces fibre diameter for one season, highlighting the range 26.1 to 28 microns as the main diameter in the region.
Shearing practices have also changed to include two options: (a) traditional timing of post-lambing shearing from the end of December to February; (b) pre-lambing shearing in late August and September. The pre-lambing shearing with positive results in lamb marking, lessened ewe mortality [69] and cleaner fleeces [35], this management arrived late in 80′ by the farmers Carlos García and Ivo Robertson. The tally-hi shearing method used in Magallanes was upgraded by New Zealand technicians. The shearing process starts with animals separated in a corral (Figure 6A) into different categories, and then they are moved into the shed (Figure 6B and C). Subsequently the sheep are sheared (Figure 6D and E), fleeces are cleaned on a table (Figure 6F) and placed into the wool press (Figure 6G) to build the bale (Figure 6H), and finally the wool bales are placed all together where each one has a note with a description of wool type and farm name (Figure 6I) and the ewe is released to outside (Figure 6J).
Figure 6.
The traditional shearing process in Magallanes, different process stages from A to J. (Image by Sergio Radic S.).
9. Lactation curve and cheese production
There is one dairy sheep operation that was set up as a pilot program in the 1990s by the University of Magallanes (coordinated by Sergio Kusanovic) in the city of Puerto Natales (Chilean Patagonia). The program uses East Friesian sheep (from Bolson city in Argentina) and was developed with the goal of cheese production at a local scale. The lactation curve (Figure 7) and cheese production is based on grassland grazing and strategic supplementation with 200 g d−1 of commercial concentrate (15% CP; 2.6 Mcal EM kg DM−1) from flushing two weeks prior to breeding through the breeding period. The sheep are fed under a grazing system in the first 100 days of pregnancy. For the last 50 days of pregnancy, 400 g DM d−1 of alfalfa hay is supplemented [73]. Because the nutritional management is mainly by grasslands, it is a way to develop organic farming, a production method with a specific market focus on products of premium quality and high standards [72].
Figure 7.
Milk yield (dotted green line) in lactation period and body live weight (solid blue line) during the year of East Friesian sheep [72].
The feed ration and body reserve are very important inputs for adequate milk yields in dairy sheep at the end of pregnancy and during lactation. For the latter, in systems that base their feeding management on grasslands, body weight at pregnancy, lambing and lactation may be considered indicators of animal nutritional status and body reserve level.
This initiative developed by the University of Magallanes produces the southernmost cheese of Chile. The higher concentrations of fat, total solids and protein (6.2%), present in sheep milk compared to goat (3.4%) and dairy cattle (3.2%), result in high yields in the production of dairy products [74]. There is a possibility to generate a brand image with this kind of cheese in the Chilean Patagonia. The commercialization of sheep cheese in Magallanes traditionally corresponds to consumers of foreign origin, but also markets to gourmet stores, hotels or restaurants, where there is the highest consumption [75].
10. Best livestock practices and animal welfare in Magallanes
In a highly globalized world characterized by increasing demands by the large international markets, the Magallanes region has some intrinsic advantages, including its geographical location, associated with characteristics of extensive production that allow for reducing the risks associated with animal welfare. Although this system minimizes human-animal interactions (limited number of operations and/or contacts)3, livestock should be managed and overseen by capable personnel to ensure the correct execution of management and create a positive human-animal interaction.
Although the concept of welfare refers to a state of physical and mental health where the animal is in complete harmony with the environment that surrounds it [76], today we focus on “one health”, a concept that entails good management and animal care that leads to good human health and positive collateral outcomes, both economic and social [77].
Animal welfare today is structured on five fundamental domains: adequate nutrition and water availability, health and disease prevention, good environment and provision of opportunities, behaviors and freedom to express them, and finally, mental state, which is determined by the experience of the four former domains, logically resulting in both negative and positive parameters. The complex part for extensive production systems is to find the right moment(s) to apply practical, quick, valid, reliable, and repeatable measuring techniques (direct and indirect indicators, based on the resources or the animal, to evaluate its state and condition) to generate an accurate picture of sheep production today in the Magallanes region.
In order to ensure a livestock sector that is both sustainable and adheres to both national (Law Chile 20380, decree-law numbers 28–29-30) and international requirements, rules, and regulations, the sheep industry, farms and livestock personnel are slowly but satisfactorily developing changes in some practices, especially those related to animal handling and painful procedures (tail docking, castration), where the Good Livestock Practices manual is one of the first to be generated on this subject in the region. It is essential today to have plans that allow for storage of adequate food and water supplies, constant health monitoring, and adequate facilities to minimize and facilitate animal handling in delicate procedures such as transport, herding, and shearing, among others, as well as allowing the manifestation of both natural and normal behaviors during production processes.
Finally, it is highly recommended that the personnel working in production units know and understand the concepts related to sheep management and production, which will result in adequate competence, minimizing risks, injuries and potential processes that generate negative effects in the production chain.
11. Sheep farming and wildlife interactions in Magallanes
The relationship between wildlife and animal production involves ecological interactions such as competition for foraging resources and space, and predation [78]. Wildlife-livestock interactions are mostly assumed to be detrimental to human economic activities, leading to wrong attitudes and prosecution of wild species in areas of coexistence with livestock [78]. The situation of sheep ranching in Magallanes is not different; sheep either compete with wild herbivores or are killed due to carnivore predation. Therefore, producer views towards wild species are generally negative [79, 80]. However, despite the economic importance of sheep production in Magallanes, studies about sheep interactions with wildlife are rather scarce, with more information from Argentinean Patagonia [81, 82].
When sheep ranching arrived in southern South America in the late 19th century [83], guanaco (Lama guanicoe), a large South American camelids and the main wild herbivore of the Patagonian steppe, numbered between 7 and 10 million individuals [84]. Since that time, guanaco have been considered the main competitor for sheep by ranchers [85], and their numbers declined to about 600,000 animals by the end of the 20th century. They currently occupy less than 40% of their original range [86]. The decline in guanaco abundance and distribution is associated with high numbers of sheep and resulting reduction in preferred forage [85]. Extensive sheep ranching seems to have produced an increasing degradation of guanaco habitat due to overgrazing, changes in the structure and composition of vegetation, displacing guanaco and changing their distribution [87]; however, sheep-guanaco interaction outcomes are still controversial [88, 89].
Available information is mostly limited to dietary composition of both species, indicating a large overlap in food items [81, 90]. It is assumed that this large herbivore consumes great amounts of vegetation, the equivalent of two to three sheep. Camelids, however, have low metabolism rates, implying lower food consumption, so the opposite situation should be considered [91]. Although ranchers in Magallanes do not place an economic value on guanaco, they are perceived as an obstacle to domestic sheep production [79]. There are efforts from Chilean government agencies under the Ministry of Agriculture to support the sustainable use of guanaco [92]. After several years of guanaco counts, annual hunting quotas under 3% of estimated guanaco population have been established to give guanaco economic value [92]. Currently, the guanaco population inhabiting productive lands in Magallanes is estimated at 297,844 individuals [93].
Other wildlife that might use similar food resources and space with sheep are herbivorous birds like the lesser rhea (Rhea pennata; [94]) and wild geese (Chloëphaga spp) like the upland goose (C. picta; [95]). However, these herbivorous birds are not seeing as competitors like guanaco because of their smaller size and lower conspicuity. Nonetheless, there is a lack of studies on wild birds interacting with sheep ranching in Magallanes and most of information occurs in Argentinean Patagonia [96] and the Falkland Islands [95].
Similarly, since the advent of sheep ranching in southern Patagonia, large predators, like puma (Puma concolor), and meso predators, like culpeo (Lycalopex culapeus) and gray foxes (L. griseous), have been interacting with sheep ranching in rural Magallanes [97]. This interaction with wild native carnivores generates economic losses to ranchers because puma and foxes are a source of sheep mortality. Additionally, the attack and predation of sheep by domestic dogs is a growing concern worldwide, and Magallanes is not an exception. In Chile, domestic dog predation on livestock lacks legal regulation.
According to official government records, carnivores impact animal production in Magallanes [98]. Between 2012 and 2017, 2259 livestock animals were killed by carnivores, 83% of which were sheep (1887 head) [98]. The majority of those attacks were reported on the Island of Tierra del Fuego (59%). If reported attacks are organized by predator species causing mortality, 78% of attacks corresponded to domestic dogs (55 events) accounting for 1855 predated livestock (82%) [98]. Foxes (Lycalopex spp) were reported to predate 208 livestock (9%), and puma predation on livestock was 1% (13 animals) [98].
Farmers hunt native carnivores despite this activity is illegal in Chile [80]. This situation could be associated to the lack of governmental programs to verify livestock mortality causes and issue compensation of economic loss [80]. Recently, sheep ranches near Torres del Paine National Park, one of the main protected areas in Magallanes, have changed their perception of puma because the presence of this large carnivore is a source of an important touristic activity in the area producing important economic revenues [80]. Other animals that are perceived as harmful for sheep farmers include raptors like southern caracara (Caracara plancus) and buzzard eagle (Geranoaetus melanoleucus), which predate on newborn lambs [99], but there are not formal reports from Magallanes.
It is necessary to differentiate sheep losses because of wildlife from those caused by deficient ranch management. Several sheep ranches seem to have incorrect estimates of appropriate stocking rate density that can cause overgrazing and degradation of the steppe that finally drive to poor animal conditions and economic losses, which is not directly related to the presence of wild herbivores. The importance of large carnivores in overall ecosystem health must be considered before lethal control. Predation prevention methods like night shelters or guard dogs, should also be used where appropriate [100].
12. The agritourism potential in Magallanes: Farm tourism or tourism on farms?
The farms in the Magallanes region have been characterized by developing and preserving an extensive infrastructure, consisting of numerous interrelated buildings to meet the demands and services of a sheep farm, which has historically been extensively developed [101]. Usually the farms are huge estates, hundreds or thousands of hectares in size, and in many of them there are still tools, machinery and furniture typical of the colonizing era from the mid-19th century to the early 20th century [102]. These locations are nestled within natural landscapes that include lakes, rivers and wide landscapes such as the Patagonian steppe, where the horizon and the sky display dramatic sunrises and sunsets. Furthermore, prior to the establishment of these ranches, these sites were inhabited by ancestral peoples who knew the territory and its resources very well [103]. All these conditions provide an ideal setting for agritourism [104] as a way to combine culture, nature, leisure and recreation in a landscape experience.
Tourism on farms in the Magallanes region is emerging and poses opportunities and challenges to innovate in regional economic development. Currently, the offer for tourism on estancias is traditional and restricted to activities typical of nature tourism such as wildlife observation, walks, horseback riding, photography and fishing, among others. To a lesser degree, activities typical of agriculture (Figure 8) are available, such as organic agriculture and observation of traditional tasks such as sheep herding or shearing, among others. Often, but not always, this offer is associated with spending the night in the manor houses itself and tasting local cuisine, so that the experience is complemented by the charm of the architectural heritage and historical legacy [101]. However, this type of tourism faces endemic problems such as seasonality, lack of specialized human resources and poor connectivity. Usually the distances are exaggerated, the accesses are tortuous, and even in many of them digital connectivity problems persist, which makes it difficult to implement online marketing and reservation systems, resulting in a loss of service. In addition, many times the tourist product offered is limited to passive observation experiences, but the tourist storytelling to enrich the visitor’s experience and feed their learning and interest, is absent. Thus, this type of tourism wanders between “farm tourism”, where the central activities are related to the ranch trade [105], or “tourism on farm”, a farm where tourist activities other than the traditional.
Figure 8.
a) Herding of sheep in Magallanes, one of the favorite activities to observe by tourists in estancias in the region (image by Claudio Vidal). b) Sheep bath, as another interesting farm task for tourism (image by Sergio Radic K.).
Today, the particularities of the tourist atlas of the Magallanes territory can be considered counterproductive for the development of farm tourism in isolated areas. The profitability of agritourism as such is low and occurs as a complementary element to other economic activities, but it is not the main one [106]. Tourist concentration is persistently monopolized and overshadowed by Torres del Paine National Park, considered by many to be the gem of Patagonia and the main pole of attraction for regional tourism [107]. Thus, perhaps a relevant option would be the diversification of tourism content on the basis of local identity; generate a local identity to offer a different product, where tourists enjoy and learn about distinctive aspects such as architecture, history, ethnography and rural life. This identity could be re-created from and for the territory, starting from the cultural histories and the memory of the ancestral peoples. There are numerous ethnographic, historical, architectural and family resources [103, 108, 109] to implement a touristic storytelling and generate an “experience scape”, as has happened in other areas of farm tourism [110]. However, tourism research is required to consolidate facts, protagonists, sites and narratives for a continuous valorization of the cultural and natural heritage with potential for the development of tourism, whether it is for farm tourism or tourism on farms.
13. Final comments
After 145 years of sheep production, the Magallanes region has become a characteristic and important territory for sheep industry, and must continue to improve the quality level of products demanded by consumers. Three key points lead the future of the industry in the region: sustainable management, markets, and human resources; but the ability to integrate all these points in the same direction will support farm success. Through technology adoption and sustainable management practices, the industry can achieve soil, water, and grassland conservation and utilize best livestock practices that improve animal welfare and sheep-wildlife interactions. Improving and/or intensifying utilization of a small percentage of each farm (approximately between 2 and 5% depending mainly to stocking rate used and the dry matter production of grasslands) will achieve sustainable and profitable long-term production. Considering the economic side of production in the region, the market currently demands lamb carcasses around 14 to 16 kg and finer wool, between 17 to 22 μm. Then, each decision making must consider existing management and farm production system (meat, wool, or dual purpose) and quality product that can be produced. Broadening market potential through diversification is an important consideration, but must be evaluated within the context of each farm, in this way tourism, dairy products or knowledge of ecosystem services could play a significant role. Finally, human resources need to be specialized to face these challenges, for which technical abilities, undergraduate and postgraduate studies are a key component. The Agricultural and Aquiculture Sciences Department of Magallanes University and the Agricultural Research Institute (Kampenaike Experimental Station) will have an important role in disseminating technical knowledge and providing professional development in our region.
Acknowledgments
This work is derived of the compromise acquired in the memorandum of understanding signed by Agricultural Research Institute (Kampenaike Experimental Station) and University of Magallanes. The authors acknowledge all technicians, students and scientists were involved in each research developed in the region in the last years. The farmers what contribute to the progress and sustainability of sheep production in Magallanes.
Conflict of interest
The authors declare no interest conflict.
\n',keywords:"Chilean Patagonia, sheep production, grazing systems, fodder crops, artificial insemination, breeding, meet quality, wool production, sheep cheese, wildlife, animal welfare, agritourism",chapterPDFUrl:"https://cdn.intechopen.com/pdfs/79396.pdf",chapterXML:"https://mts.intechopen.com/source/xml/79396.xml",downloadPdfUrl:"/chapter/pdf-download/79396",previewPdfUrl:"/chapter/pdf-preview/79396",totalDownloads:68,totalViews:0,totalCrossrefCites:0,dateSubmitted:"August 10th 2021",dateReviewed:"September 17th 2021",datePrePublished:"November 29th 2021",datePublished:"April 28th 2022",dateFinished:"November 20th 2021",readingETA:"0",abstract:"The Magallanes region in Chilean Patagonia encompasses 13 million hectares with approximately 3.6 million used for agricultural and livestock systems. This portion is located to the east of the Andean Mountain chain in the rain shadow zone, with annual precipitation increasing along an east to west gradient from 200 to almost 1,000 mm. To fully describe sheep farming in the Magallanes region, many topics need to be addressed, including sheep production and management, existing vegetative communities, livestock-wildlife interactions, and economic diversification into agritourism and another sheep industry products. All these give shape to the story of the development of sheep farming in Magallanes, which is important at the regional and national level. Three key points are identified that together can lead to a successful future for the industry: sustainable management, human resources and the market.",reviewType:"peer-reviewed",bibtexUrl:"/chapter/bibtex/79396",risUrl:"/chapter/ris/79396",signatures:"Sergio Radic-Schilling, Francisco Sales, Raúl Lira, René Muñoz-Arriagada, Paulo Corti, Nilo Covacevich, Jorge Ivelic-Sáez, Iván Ordoñez, Osvaldo Vidal, Ricardo Echeverría and Camila Sandoval",book:{id:"11008",type:"book",title:"Sheep Farming",subtitle:"Herds Husbandry, Management System, Reproduction and Improvement of Animal Health",fullTitle:"Sheep Farming - Herds Husbandry, Management System, Reproduction and Improvement of Animal Health",slug:"sheep-farming-herds-husbandry-management-system-reproduction-and-improvement-of-animal-health",publishedDate:"April 28th 2022",bookSignature:"Manuel Gonzalez Ronquillo and Carlos Palacios Riocerezo",coverURL:"https://cdn.intechopen.com/books/images_new/11008.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",isbn:"978-1-83969-711-1",printIsbn:"978-1-83969-710-4",pdfIsbn:"978-1-83969-712-8",isAvailableForWebshopOrdering:!0,editors:[{id:"175967",title:"Dr.",name:"Manuel",middleName:null,surname:"Gonzalez Ronquillo",slug:"manuel-gonzalez-ronquillo",fullName:"Manuel Gonzalez Ronquillo"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}},authors:[{id:"270986",title:"Ph.D.",name:"Sergio",middleName:null,surname:"Radic",fullName:"Sergio Radic",slug:"sergio-radic",email:"sergio.radic@umag.cl",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"428989",title:"Dr.",name:"Francisco",middleName:null,surname:"Sales",fullName:"Francisco Sales",slug:"francisco-sales",email:"fsales@inia.cl",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"428990",title:"MSc.",name:"Raúl",middleName:null,surname:"Lira",fullName:"Raúl Lira",slug:"raul-lira",email:"rlira@inia.cl",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"428991",title:"MSc.",name:"René",middleName:null,surname:"Muñoz-Arriagada",fullName:"René Muñoz-Arriagada",slug:"rene-munoz-arriagada",email:"rene.munoz@umag.cl",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"428992",title:"Dr.",name:"Paulo",middleName:null,surname:"Corti",fullName:"Paulo Corti",slug:"paulo-corti",email:"pcorti@uach.cl",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"428993",title:"Dr.",name:"Nilo",middleName:null,surname:"Covacevich",fullName:"Nilo Covacevich",slug:"nilo-covacevich",email:"covacevichnilo@gmail.com",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"428994",title:"MSc.",name:"Jorge",middleName:null,surname:"Ivelic-Sáez",fullName:"Jorge Ivelic-Sáez",slug:"jorge-ivelic-saez",email:"jorge.ivelic@inia.cl",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"428995",title:"Dr.",name:"Iván",middleName:null,surname:"Ordoñez",fullName:"Iván Ordoñez",slug:"ivan-ordonez",email:"ivan.ordonez@inia.cl",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"428996",title:"Dr.",name:"Osvaldo",middleName:null,surname:"Vidal",fullName:"Osvaldo Vidal",slug:"osvaldo-vidal",email:"osvaldo.vidal@umag.cl",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"428997",title:"Mr.",name:"Ricardo",middleName:null,surname:"Echeverría",fullName:"Ricardo Echeverría",slug:"ricardo-echeverria",email:"ricardo.echeverria@umag.cl",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"428998",title:"Dr.",name:"Camila",middleName:null,surname:"Sandoval",fullName:"Camila Sandoval",slug:"camila-sandoval",email:"camila.sandoval.torres@inia.cl",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null}],sections:[{id:"sec_1",title:"1. Introduction",level:"1"},{id:"sec_2",title:"2. Geographical area and weather",level:"1"},{id:"sec_3",title:"3. Grazing systems in Patagonian grasslands",level:"1"},{id:"sec_3_2",title:"3.1 Patagonian grazing systems",level:"2"},{id:"sec_3_3",title:"3.1.1 Continuous grazing system",level:"3"},{id:"sec_4_3",title:"3.1.2 Rotational grazing",level:"3"},{id:"sec_6_2",title:"3.2 Future perspective",level:"2"},{id:"sec_8",title:"4. Fodder crop",level:"1"},{id:"sec_9",title:"5. Artificial insemination",level:"1"},{id:"sec_9_2",title:"5.1 Artificial insemination: a productive tool",level:"2"},{id:"sec_9_3",title:"5.1.1 Preparing the animals for artificial insemination with fresh semen",level:"3"},{id:"sec_10_3",title:"5.1.2 Estrus synchronization protocols",level:"3"},{id:"sec_11_3",title:"5.1.3 Artificial insemination facilities in Patagonia",level:"3"},{id:"sec_12_3",title:"5.1.4 Fresh semen artificial insemination",level:"3"},{id:"sec_13_3",title:"5.1.5 Frozen semen artificial insemination",level:"3"},{id:"sec_15_2",title:"5.2 Management concepts associated to artificial insemination",level:"2"},{id:"sec_17",title:"6. Breeding, breeds, and management of sheep production system in Magallanes",level:"1"},{id:"sec_17_2",title:"6.1 Animal and natural resources",level:"2"},{id:"sec_17_3",title:"6.1.1 Management",level:"3"},{id:"sec_20",title:"7. Meat quality",level:"1"},{id:"sec_20_2",title:"7.1 The role of Magallanes lamb meat in human nutrition",level:"2"},{id:"sec_22",title:"8. Wool production",level:"1"},{id:"sec_23",title:"9. Lactation curve and cheese production",level:"1"},{id:"sec_24",title:"10. Best livestock practices and animal welfare in Magallanes",level:"1"},{id:"sec_25",title:"11. Sheep farming and wildlife interactions in Magallanes",level:"1"},{id:"sec_26",title:"12. The agritourism potential in Magallanes: Farm tourism or tourism on farms?",level:"1"},{id:"sec_27",title:"13. Final comments",level:"1"},{id:"sec_28",title:"Acknowledgments",level:"1"},{id:"sec_31",title:"Conflict of interest",level:"1"}],chapterReferences:[{id:"B1",body:'Martinic M. Nociones De Geografía De Magallanes. Ediciones de la Universidad de Magallanes, Punta Arenas; 2001.'},{id:"B2",body:'Fick S, y Hijmans R. WorldClim 2: new 1 km spatial resolution climate surfaces for global land areas. 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DOI: 10.4067/S0718-22442011000100001'},{id:"B84",body:'González BA, Palma RE, Zapata B, Marín JC. Taxonomic and biogeographical status of guanaco Lama guanicoe (Artiodactyla, Camelidae). Mammal Review. 2006; 36:157-178. DOI: 10.1111/j.1365-2907.2006.00084.x'},{id:"B85",body:'Baldi R, Novaro A, Funes M, Walker S, Ferrando P, Failla M, Carmanchahi P. Guanaco management in Patagonian rangelands: a conservation opportunity on the brink of collapse. In: du Toit JT, Kock R, Deutsch JC, editors. Wild Rangelands. Wiley; 2010. p. 266-290. DOI: 10.1002/9781444317091.ch10'},{id:"B86",body:'Baldi RB, Acebes P, Cuéllar E, Funes M, Hoces D, Puig S, Franklin WL. Lama guanicoe. The IUCN Red List of Threatened Species 2016. 2016. Available from: https://dx.doi.org/10.2305/IUCN.UK.2016-1.RLTS.T11186A18540211.en'},{id:"B87",body:'Moraga C, Funes M, Pizarro J, Briceño C, Novaro A. 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Diet, Feeding behaviour and food intake of the upland goose (Chloëphaga picta) and ruddy-headed goose (C. rubidiceps) in the Falkland Islands. Journal of Applied Ecology. 1988; 19783-804. DOI: 10.2307/2403282'},{id:"B96",body:'Antún M, Baldi R, Bandieri LM, D’Agostino RL. Analysis of the spatial variation in the abundance of lesser rheas using density surface models. Wildlife Research. 2018; 45:47-54. DOI: 10.1071/WR16233'},{id:"B97",body:'Nanni AS, Teel T, Lucherini M. Predation on livestock and its influence on tolerance toward pumas in agroecosystems of the Argentine Dry Chaco. Human Dimensions of Wildlife. DOI: 10.1080/10871209.2019.1668987'},{id:"B98",body:'Soto N. Perros bravíos en Magallanes, contexto y marco normativo. In: Comisión de Agricultura, Senado de la República de Chile; 21 January 2019; Valparaíso, Chile.'},{id:"B99",body:'Moreira-Arce D, Ugarte CS, Zorondo-Rodríguez F, Simonetti JA. 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Etnobiológica 3: 1-20.'},{id:"B104",body:'Blanco M. & Riveros H. 2010. El agroturismo como diversificación de la actividad agropecuaria y agroindustrial. In: Desarrollo de los agronegocios y la agroindustria rural en América Latina y el Caribe. Conceptos, instrumentos y casos de cooperación técnica, Instituto Interamericano de Cooperación para la Agricultura.'},{id:"B105",body:'Phillip S., Hunter C. & Blackstock K. 2010. A typology for defining agritourism. Tourism Management 31: 754-758.'},{id:"B106",body:'Blanco M. 2007. Agroturismo en Costa Rica. Retos y Oportunidades. Escuela Centroamericana de Ganadería (ECAG) 40: 25-27.'},{id:"B107",body:'Vidal O.J. 2012. Torres del Paine, ecoturismo e incendios forestales: perspectivas de investigación y manejo para una biodiversidad erosionada. Revista Bosque Nativo 50: 33-39.'},{id:"B108",body:'Prieto A. 1988. Cazadores-recolectores del Istmo de Brunswick. 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Since then, he has been working as an Adjunct Professor in the same Department at the University of Pavia. His research activity during the first years was primarily focused on the purification and structural characterization of enzymes from animal and plant sources. During this period, Prof. Iadarola familiarized himself with the conventional techniques used in column chromatography, spectrophotometry, manual Edman degradation, and electrophoresis). Since 1995, he has been working on: i) the determination in biological fluids (serum, urine, bronchoalveolar lavage, sputum) of proteolytic activities involved in the degradation processes of connective tissue matrix, and ii) on the identification of biological markers of lung diseases. In this context, he has developed and validated new methodologies (e.g., Capillary Electrophoresis coupled to Laser-Induced Fluorescence, CE-LIF) whose application enabled him to determine both the amounts of biochemical markers (Desmosines) in urine/serum of patients affected by Chronic Obstructive Pulmonary Disease (COPD) and the activity of proteolytic enzymes (Human Neutrophil Elastase, Cathepsin G, Pseudomonas aeruginosa elastase) in sputa of these patients. More recently, Prof. Iadarola was involved in developing techniques such as two-dimensional electrophoresis coupled to liquid chromatography/mass spectrometry (2DE-LC/MS) for the proteomic analysis of biological fluids aimed at the identification of potential biomarkers of different lung diseases. He is the author of about 150 publications (According to Scopus: H-Index: 23; Total citations: 1568- According to WOS: H-Index: 20; Total Citations: 1296) of peer-reviewed international journals. 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She gained considerable experience in developing and validating new methodologies whose applications allowed her to determine both the amount of biomarkers (Desmosine and Isodesmosine) in the urine of patients affected by COPD, and the activity of proteolytic enzymes (HNE, Cathepsin G, Pseudomonas aeruginosa elastase) in the sputa of these patients. Simona Viglio was also involved in research dealing with the supplementation of amino acids in patients with brain injury and chronic heart failure. She is presently engaged in the development of 2-DE and LC-MS techniques for the study of proteomics in biological fluids. The aim of this research is the identification of potential biomarkers of lung diseases. She is an author of about 90 publications (According to Scopus: H-Index: 23; According to WOS: H-Index: 20) on peer-reviewed journals, a member of the “Società Italiana di Biochimica e Biologia Molecolare,“ and a Consultant Reviewer for International Journal of Molecular Science, Journal of Chromatography A, COPD, Plos ONE and Nutritional Neuroscience.",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorThree:null}]},overviewPageOFChapters:{paginationCount:49,paginationItems:[{id:"80495",title:"Iron in Cell Metabolism and Disease",doi:"10.5772/intechopen.101908",signatures:"Eeka Prabhakar",slug:"iron-in-cell-metabolism-and-disease",totalDownloads:1,totalCrossrefCites:0,totalDimensionsCites:null,authors:null,book:{title:"Iron Metabolism - Iron a Double‐Edged Sword",coverURL:"https://cdn.intechopen.com/books/images_new/10842.jpg",subseries:{id:"17",title:"Metabolism"}}},{id:"81799",title:"Cross Talk of Purinergic and Immune Signaling: Implication in Inflammatory and Pathogenic Diseases",doi:"10.5772/intechopen.104978",signatures:"Richa Rai",slug:"cross-talk-of-purinergic-and-immune-signaling-implication-in-inflammatory-and-pathogenic-diseases",totalDownloads:7,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Purinergic System",coverURL:"https://cdn.intechopen.com/books/images_new/10801.jpg",subseries:{id:"17",title:"Metabolism"}}},{id:"81764",title:"Involvement of the Purinergic System in Cell Death in Models of Retinopathies",doi:"10.5772/intechopen.103935",signatures:"Douglas Penaforte Cruz, Marinna Garcia Repossi and Lucianne Fragel Madeira",slug:"involvement-of-the-purinergic-system-in-cell-death-in-models-of-retinopathies",totalDownloads:4,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Purinergic System",coverURL:"https://cdn.intechopen.com/books/images_new/10801.jpg",subseries:{id:"17",title:"Metabolism"}}},{id:"81756",title:"Alteration of Cytokines Level and Oxidative Stress Parameters in COVID-19",doi:"10.5772/intechopen.104950",signatures:"Marija Petrusevska, Emilija Atanasovska, Dragica Zendelovska, Aleksandar Eftimov and Katerina Spasovska",slug:"alteration-of-cytokines-level-and-oxidative-stress-parameters-in-covid-19",totalDownloads:8,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Chemokines Updates",coverURL:"https://cdn.intechopen.com/books/images_new/11672.jpg",subseries:{id:"18",title:"Proteomics"}}}]},overviewPagePublishedBooks:{paginationCount:27,paginationItems:[{type:"book",id:"7006",title:"Biochemistry and Health Benefits of Fatty Acids",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7006.jpg",slug:"biochemistry-and-health-benefits-of-fatty-acids",publishedDate:"December 19th 2018",editedByType:"Edited by",bookSignature:"Viduranga Waisundara",hash:"c93a00abd68b5eba67e5e719f67fd20b",volumeInSeries:1,fullTitle:"Biochemistry and Health Benefits of Fatty Acids",editors:[{id:"194281",title:"Dr.",name:"Viduranga Y.",middleName:null,surname:"Waisundara",slug:"viduranga-y.-waisundara",fullName:"Viduranga Y. 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She has more than fifteen years of teaching and research experience. She has published more than 550 scientific publications/communications, including 15 books, 50 book chapters, 100 original research papers, 380 research communications in national and international conferences, and 12 patents. She is a member of the editorial board of five journals and acts as a reviewer for several national and international journals. Her research interests include microalgal biotechnology with an emphasis on microalgae-based products.",institutionString:"Universidade Federal de Santa Maria",institution:{name:"Universidade Federal de Santa Maria",institutionURL:null,country:{name:"Brazil"}}}]},{type:"book",id:"7953",title:"Bioluminescence",subtitle:"Analytical Applications and Basic Biology",coverURL:"https://cdn.intechopen.com/books/images_new/7953.jpg",slug:"bioluminescence-analytical-applications-and-basic-biology",publishedDate:"September 25th 2019",editedByType:"Edited by",bookSignature:"Hirobumi Suzuki",hash:"3a8efa00b71abea11bf01973dc589979",volumeInSeries:4,fullTitle:"Bioluminescence - Analytical Applications and Basic Biology",editors:[{id:"185746",title:"Dr.",name:"Hirobumi",middleName:null,surname:"Suzuki",slug:"hirobumi-suzuki",fullName:"Hirobumi Suzuki",profilePictureURL:"https://mts.intechopen.com/storage/users/185746/images/system/185746.png",biography:"Dr. Hirobumi Suzuki received his Ph.D. in 1997 from Tokyo Metropolitan University, Japan, where he studied firefly phylogeny and the evolution of mating systems. He is especially interested in the genetic differentiation pattern and speciation process that correlate to the flashing pattern and mating behavior of some fireflies in Japan. He then worked for Olympus Corporation, a Japanese manufacturer of optics and imaging products, where he was involved in the development of luminescence technology and produced a bioluminescence microscope that is currently being used for gene expression analysis in chronobiology, neurobiology, and developmental biology. Dr. Suzuki currently serves as a visiting researcher at Kogakuin University, Japan, and also a vice president of the Japan Firefly Society.",institutionString:"Kogakuin University",institution:null}]}]},openForSubmissionBooks:{},onlineFirstChapters:{},subseriesFiltersForOFChapters:[],publishedBooks:{},subseriesFiltersForPublishedBooks:[],publicationYearFilters:[],authors:{}},subseries:{item:{id:"22",type:"subseries",title:"Applied Intelligence",keywords:"Machine Learning, Intelligence Algorithms, Data Science, Artificial Intelligence, Applications on Applied Intelligence",scope:"This field is the key in the current industrial revolution (Industry 4.0), where the new models and developments are based on the knowledge generation on applied intelligence. 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His research lines are biometrics, biomedical signals and images, data mining, classification system, signal and image processing, machine learning, and environmental intelligence. He has researched in 52 international and Spanish research projects, some of them as head researcher. He is co-author of 4 books, co-editor of 27 proceedings books, guest editor for 8 JCR-ISI international journals, and up to 24 book chapters. He has over 450 papers published in international journals and conferences (81 of them indexed on JCR – ISI - Web of Science). He has published seven patents in the Spanish Patent and Trademark Office. He has been a supervisor on 8 Ph.D. theses (11 more are under supervision), and 130 master theses. He is the founder of The IEEE IWOBI conference series and the president of its Steering Committee, as well as the founder of both the InnoEducaTIC and APPIS conference series. He is an evaluator of project proposals for the European Union (H2020), Medical Research Council (MRC, UK), Spanish Government (ANECA, Spain), Research National Agency (ANR, France), DAAD (Germany), Argentinian Government, and the Colombian Institutions. He has been a reviewer in different indexed international journals (<70) and conferences (<250) since 2001. He has been a member of the IASTED Technical Committee on Image Processing from 2007 and a member of the IASTED Technical Committee on Artificial Intelligence and Expert Systems from 2011. \n\nHe has held the general chair position for the following: ACM-APPIS (2020, 2021), IEEE-IWOBI (2019, 2020 and 2020), A PPIS (2018, 2019), IEEE-IWOBI (2014, 2015, 2017, 2018), InnoEducaTIC (2014, 2017), IEEE-INES (2013), NoLISP (2011), JRBP (2012), and IEEE-ICCST (2005)\n\nHe is an associate editor of the Computational Intelligence and Neuroscience Journal (Hindawi – Q2 JCR-ISI). He was vice dean from 2004 to 2010 in the Higher Technical School of Telecommunication Engineers at ULPGC and the vice dean of Graduate and Postgraduate Studies from March 2013 to November 2017. 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