Description of the Data
\\n\\n
IntechOpen Book Series will also publish a program of research-driven Thematic Edited Volumes that focus on specific areas and allow for a more in-depth overview of a particular subject.
\\n\\nIntechOpen Book Series will be launching regularly to offer our authors and editors exciting opportunities to publish their research Open Access. We will begin by relaunching some of our existing Book Series in this innovative book format, and will expand in 2022 into rapidly growing research fields that are driving and advancing society.
\\n\\nLaunching 2021
\\n\\nArtificial Intelligence, ISSN 2633-1403
\\n\\nVeterinary Medicine and Science, ISSN 2632-0517
\\n\\nBiochemistry, ISSN 2632-0983
\\n\\nBiomedical Engineering, ISSN 2631-5343
\\n\\nInfectious Diseases, ISSN 2631-6188
\\n\\nPhysiology (Coming Soon)
\\n\\nDentistry (Coming Soon)
\\n\\nWe invite you to explore our IntechOpen Book Series, find the right publishing program for you and reach your desired audience in record time.
\\n\\nNote: Edited in October 2021
\\n"}]',published:!0,mainMedia:{caption:"",originalUrl:"/media/original/132"}},components:[{type:"htmlEditorComponent",content:'With the desire to make book publishing more relevant for the digital age and offer innovative Open Access publishing options, we are thrilled to announce the launch of our new publishing format: IntechOpen Book Series.
\n\nDesigned to cover fast-moving research fields in rapidly expanding areas, our Book Series feature a Topic structure allowing us to present the most relevant sub-disciplines. Book Series are headed by Series Editors, and a team of Topic Editors supported by international Editorial Board members. Topics are always open for submissions, with an Annual Volume published each calendar year.
\n\nAfter a robust peer-review process, accepted works are published quickly, thanks to Online First, ensuring research is made available to the scientific community without delay.
\n\nOur innovative Book Series format brings you:
\n\nIntechOpen Book Series will also publish a program of research-driven Thematic Edited Volumes that focus on specific areas and allow for a more in-depth overview of a particular subject.
\n\nIntechOpen Book Series will be launching regularly to offer our authors and editors exciting opportunities to publish their research Open Access. We will begin by relaunching some of our existing Book Series in this innovative book format, and will expand in 2022 into rapidly growing research fields that are driving and advancing society.
\n\nLaunching 2021
\n\nArtificial Intelligence, ISSN 2633-1403
\n\nVeterinary Medicine and Science, ISSN 2632-0517
\n\nBiochemistry, ISSN 2632-0983
\n\nBiomedical Engineering, ISSN 2631-5343
\n\nInfectious Diseases, ISSN 2631-6188
\n\nPhysiology (Coming Soon)
\n\nDentistry (Coming Soon)
\n\nWe invite you to explore our IntechOpen Book Series, find the right publishing program for you and reach your desired audience in record time.
\n\nNote: Edited in October 2021
\n'}],latestNews:[{slug:"intechopen-supports-asapbio-s-new-initiative-publish-your-reviews-20220729",title:"IntechOpen Supports ASAPbio’s New Initiative Publish Your Reviews"},{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"}]},book:{item:{type:"book",id:"3620",leadTitle:null,fullTitle:"Factory Automation",title:"Factory Automation",subtitle:null,reviewType:"peer-reviewed",abstract:"Factory automation has evolved significantly in the last few decades, and is today a complex, interdisciplinary, scientific area. In this book a selection of papers on topics related to factory automation is presented, covering a broad spectrum, so that the reader may become familiar with the various fields, and also study them in more depth where required. Within various chapters in this book, special attention is given to distributed applications and their use of networks, since it is one of the most relevant subjects in the evolution of factory automation. Different Medium Access Control and networks are analyzed, while Ethernet and Wireless networks are looked at in more detail, since they are among the hottest topics in recent research. Another important subject is everything concerning the increase in the complexity of factory automation, and the need for flexibility and interoperability. Finally the use of \r\nmulti-agent systems, advanced control, formal methods, or the application in this field of RFID, are additional examples of the ideas and disciplines that experts around the world have analyzed in their work.",isbn:null,printIsbn:"978-953-307-024-7",pdfIsbn:"978-953-51-5911-7",doi:"10.5772/231",price:159,priceEur:175,priceUsd:205,slug:"factory-automation",numberOfPages:604,isOpenForSubmission:!1,isInWos:null,isInBkci:!1,hash:null,bookSignature:"Javier Silvestre-Blanes",publishedDate:"March 1st 2010",coverURL:"https://cdn.intechopen.com/books/images_new/3620.jpg",numberOfDownloads:95048,numberOfWosCitations:58,numberOfCrossrefCitations:77,numberOfCrossrefCitationsByBook:1,numberOfDimensionsCitations:119,numberOfDimensionsCitationsByBook:2,hasAltmetrics:1,numberOfTotalCitations:254,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:null,dateEndSecondStepPublish:null,dateEndThirdStepPublish:null,dateEndFourthStepPublish:null,dateEndFifthStepPublish:null,currentStepOfPublishingProcess:1,indexedIn:"1,2,3,4,5,6,7",editedByType:"Edited by",kuFlag:!1,featuredMarkup:null,editors:[{id:"1118",title:"Dr.",name:"Javier",middleName:null,surname:"Silvestre-Blanes",slug:"javier-silvestre-blanes",fullName:"Javier Silvestre-Blanes",profilePictureURL:"https://mts.intechopen.com/storage/users/1118/images/system/1118.jpg",biography:"Javier Silvestre-Blanes (M’02) received the\nLicenciatura degree in computer engineering and\nthe Ph.D. degree in computer architecture from\nthe Universidad Politécnica de Valencia (UPV),\nValencia, Spain, in 1999 and 2003, respectively.\nHe was a Computer Vision Engineer in a research\nand development institute in Alcoy, Spain. He is\ncurrently an Associate Professor with the Computer\nEngineering Department, UPV, where he is also a\nSenior Researcher with the Instituto Tecnológico de\nInformática. His research interests include real-time\nnetworks, multimedia systems, and communications.\nDr. Silvestre-Blanes is a member of the IEEE Industrial Electronics Society.",institutionString:null,position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"0",totalChapterViews:"0",totalEditedBooks:"1",institution:{name:"Universitat Politècnica de València",institutionURL:null,country:{name:"Spain"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"796",title:"Automation Engineering",slug:"automation-engineering"}],chapters:[{id:"10818",title:"Engineering Processes for Decentralized Factory Automation Systems",doi:"10.5772/9504",slug:"engineering-processes-for-decentralized-factory-automation-systems",totalDownloads:3909,totalCrossrefCites:20,totalDimensionsCites:29,hasAltmetrics:0,abstract:null,signatures:"Thomas Wagner, Carolin Hausner, Jurgen Elger, Ulrich Lowen and Arndt Luder",downloadPdfUrl:"/chapter/pdf-download/10818",previewPdfUrl:"/chapter/pdf-preview/10818",authors:[null],corrections:null},{id:"10831",title:"Wireless Technologies in Factory Automation",doi:"10.5772/9517",slug:"wireless-technologies-in-factory-automation",totalDownloads:3258,totalCrossrefCites:3,totalDimensionsCites:3,hasAltmetrics:0,abstract:null,signatures:"Aurel Buda, Volker Schuermann and Joerg F. Wollert",downloadPdfUrl:"/chapter/pdf-download/10831",previewPdfUrl:"/chapter/pdf-preview/10831",authors:[null],corrections:null},{id:"10836",title:"A Real-Time Wireless Communication System Based on 802.11 MAC",doi:"10.5772/9522",slug:"a-real-time-wireless-communication-system-based-on-802-11-mac",totalDownloads:3316,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:null,signatures:"Gennaro Boggia, Pietro Camarda, L. Alfredo Grieco and Giammarco Zacheo",downloadPdfUrl:"/chapter/pdf-download/10836",previewPdfUrl:"/chapter/pdf-preview/10836",authors:[null],corrections:null},{id:"10829",title:"When the Industry Goes Wireless: Drivers, Requirements, Technology and Future Trends",doi:"10.5772/9515",slug:"when-the-industry-goes-wireless-drivers-requirements-technology-and-future-trends",totalDownloads:2753,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:null,signatures:"Simon Carlsen and Stig Petersen",downloadPdfUrl:"/chapter/pdf-download/10829",previewPdfUrl:"/chapter/pdf-preview/10829",authors:[null],corrections:null},{id:"10828",title:"Rapid Application Development for Wireless Sensor Networks",doi:"10.5772/9514",slug:"rapid-application-development-for-wireless-sensor-networks",totalDownloads:3152,totalCrossrefCites:1,totalDimensionsCites:2,hasAltmetrics:0,abstract:null,signatures:"Mohammad Mostafizur Rahman Mozumdar and Luciano Lavagno",downloadPdfUrl:"/chapter/pdf-download/10828",previewPdfUrl:"/chapter/pdf-preview/10828",authors:[null],corrections:null},{id:"10820",title:"VAN Applied to Control of Utilities Networks - Requirements and Capabilities",doi:"10.5772/9506",slug:"van-applied-to-control-of-utilities-networks-requirements-and-capabilities",totalDownloads:1996,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:null,signatures:"Javier Silverstre-Blanes, Victor-M. Sempere-Paya and Teresa Albero-Albero",downloadPdfUrl:"/chapter/pdf-download/10820",previewPdfUrl:"/chapter/pdf-preview/10820",authors:[null],corrections:null},{id:"10844",title:"Wireless Sensor Networks for Networked Manufacturing Systems",doi:"10.5772/9530",slug:"wireless-sensor-networks-for-networked-manufacturing-systems",totalDownloads:3801,totalCrossrefCites:0,totalDimensionsCites:4,hasAltmetrics:0,abstract:null,signatures:"L. Q. Zhuang, D. H. Zhang and M. M. Wong",downloadPdfUrl:"/chapter/pdf-download/10844",previewPdfUrl:"/chapter/pdf-preview/10844",authors:[null],corrections:null},{id:"10834",title:"Wired and Wireless Reliable Real-Time Communication in Industrial Systems",doi:"10.5772/9520",slug:"wired-and-wireless-reliable-real-time-communication-in-industrial-systems",totalDownloads:2242,totalCrossrefCites:1,totalDimensionsCites:2,hasAltmetrics:0,abstract:null,signatures:"Magnus Jonsson and Kristina Kunert",downloadPdfUrl:"/chapter/pdf-download/10834",previewPdfUrl:"/chapter/pdf-preview/10834",authors:[null],corrections:null},{id:"10830",title:"A Perspective on the IEEE 802.11e Protocol for the Factory Floor",doi:"10.5772/9516",slug:"a-perspective-on-the-ieee-802-11e-protocol-for-the-factory-floor",totalDownloads:2726,totalCrossrefCites:1,totalDimensionsCites:3,hasAltmetrics:0,abstract:null,signatures:"Lucia Lo Bello, Emanuele Toscano and Salvatore Vittorio",downloadPdfUrl:"/chapter/pdf-download/10830",previewPdfUrl:"/chapter/pdf-preview/10830",authors:[null],corrections:null},{id:"10846",title:"Wireless Sensor Networks in Industrial Automation",doi:"10.5772/9532",slug:"wireless-sensor-networks-in-industrial-automation",totalDownloads:5367,totalCrossrefCites:18,totalDimensionsCites:24,hasAltmetrics:0,abstract:null,signatures:"Marko Paavola and Kauko Leiviska",downloadPdfUrl:"/chapter/pdf-download/10846",previewPdfUrl:"/chapter/pdf-preview/10846",authors:[null],corrections:null},{id:"10819",title:"Analysis of Switched Ethernet for Real-Time Transmission",doi:"10.5772/9505",slug:"analysis-of-switched-ethernet-for-real-time-transmission",totalDownloads:2973,totalCrossrefCites:1,totalDimensionsCites:3,hasAltmetrics:0,abstract:null,signatures:"Joan Vila-Carbo, Joaquim Tur-Massanet and Enrique Hernandez-Orallo",downloadPdfUrl:"/chapter/pdf-download/10819",previewPdfUrl:"/chapter/pdf-preview/10819",authors:[null],corrections:null},{id:"10843",title:"Token Passing Techniques for Hard Real-Time Communication",doi:"10.5772/9529",slug:"token-passing-techniques-for-hard-real-time-communication",totalDownloads:2849,totalCrossrefCites:4,totalDimensionsCites:6,hasAltmetrics:0,abstract:null,signatures:"Gianluca Franchino, Giorgio C. Buttazzo and Tullio Facchinetti",downloadPdfUrl:"/chapter/pdf-download/10843",previewPdfUrl:"/chapter/pdf-preview/10843",authors:[null],corrections:null},{id:"10838",title:"Performance and Reliability of Fault-Tolerant Ethernet Networked Control Systems",doi:"10.5772/9524",slug:"performance-and-reliability-of-fault-tolerant-ethernet-networked-control-systems",totalDownloads:2765,totalCrossrefCites:0,totalDimensionsCites:3,hasAltmetrics:0,abstract:null,signatures:"Ramez M. Daoud, Hassanein H. Amer and Hany M. ElSayed",downloadPdfUrl:"/chapter/pdf-download/10838",previewPdfUrl:"/chapter/pdf-preview/10838",authors:[null],corrections:null},{id:"10824",title:"Study of Event-based Sampling Techniques and Their Influence on Greenhouse Climate Control with Wireless Sensors Network",doi:"10.5772/9510",slug:"study-of-event-based-sampling-techniques-and-their-influence-on-greenhouse-climate-control-with-wire",totalDownloads:2958,totalCrossrefCites:1,totalDimensionsCites:2,hasAltmetrics:0,abstract:null,signatures:"Andrzej Pawlowski, Jose L. Guzman, Francisco Rodriguez, Manuel Berenguel, Jose Sanchez and Sebastian Dormido",downloadPdfUrl:"/chapter/pdf-download/10824",previewPdfUrl:"/chapter/pdf-preview/10824",authors:[null],corrections:null},{id:"10823",title:"3D RFID Simulation and Design - Factory Automation",doi:"10.5772/9509",slug:"3d-rfid-simulation-and-design-factory-automation",totalDownloads:4176,totalCrossrefCites:1,totalDimensionsCites:2,hasAltmetrics:0,abstract:null,signatures:"Wei Liu and Ming Mao Wong",downloadPdfUrl:"/chapter/pdf-download/10823",previewPdfUrl:"/chapter/pdf-preview/10823",authors:[null],corrections:null},{id:"10845",title:"Robustness Enhancement of Networked Control Systems",doi:"10.5772/9531",slug:"robustness-enhancement-of-networked-control-systems",totalDownloads:2104,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:null,signatures:"Michal Morawski and Antoni Zajaczkowski",downloadPdfUrl:"/chapter/pdf-download/10845",previewPdfUrl:"/chapter/pdf-preview/10845",authors:[null],corrections:null},{id:"10826",title:"The Role of Business-to-Control Agents in Next Generation Automation Enterprise Systems",doi:"10.5772/9512",slug:"the-role-of-business-to-control-agents-in-next-generation-automation-enterprise-systems",totalDownloads:2075,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:null,signatures:"Francisco P. Maturana and Eugene Liberman",downloadPdfUrl:"/chapter/pdf-download/10826",previewPdfUrl:"/chapter/pdf-preview/10826",authors:[null],corrections:null},{id:"10827",title:"A Multiagent Architecture Based in aFoundation Fieldbus Network Function Blocks",doi:"10.5772/9513",slug:"a-multiagent-architecture-based-in-afoundation-fieldbus-network-function-blocks",totalDownloads:2668,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:null,signatures:"Vinicius Ponte Machado, Dennis Brandao, Adriao Duarte Doria Neto and Jorge Dantas de Melo",downloadPdfUrl:"/chapter/pdf-download/10827",previewPdfUrl:"/chapter/pdf-preview/10827",authors:[null],corrections:null},{id:"10837",title:"Production System’s Life Cycle-Oriented Innovation of Industrial Information Systems",doi:"10.5772/9523",slug:"production-system-s-life-cycle-oriented-innovation-of-industrial-information-systems",totalDownloads:3243,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:null,signatures:"Dencovski Kristian, Lowen Ulrich, Holm Timo, Amberg Michael, Maurmaier Mathias and Gohner Peter",downloadPdfUrl:"/chapter/pdf-download/10837",previewPdfUrl:"/chapter/pdf-preview/10837",authors:[null],corrections:null},{id:"10825",title:"Asynchronous Analogue-to-Digital Conversion Techniques",doi:"10.5772/9511",slug:"asynchronous-analogue-to-digital-conversion-techniques",totalDownloads:4333,totalCrossrefCites:0,totalDimensionsCites:1,hasAltmetrics:0,abstract:null,signatures:"Nikos Petrellis, Michael Birbas, John Kikidis and Alex Birbas",downloadPdfUrl:"/chapter/pdf-download/10825",previewPdfUrl:"/chapter/pdf-preview/10825",authors:[null],corrections:null},{id:"10833",title:"Implementation of the Delay Compensator Approach",doi:"10.5772/9519",slug:"implementation-of-the-delay-compensator-approach",totalDownloads:2259,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:null,signatures:"Ana Antunes, Fernando Dias, Jose Vieira and Alexandre Mota",downloadPdfUrl:"/chapter/pdf-download/10833",previewPdfUrl:"/chapter/pdf-preview/10833",authors:[null],corrections:null},{id:"10835",title:"Control of Robot Interaction Forces Using Evolutionary Techniques",doi:"10.5772/9521",slug:"control-of-robot-interaction-forces-using-evolutionary-techniques",totalDownloads:2210,totalCrossrefCites:0,totalDimensionsCites:1,hasAltmetrics:0,abstract:null,signatures:"Jose de Gea, Yohannes Kassahun and Frank Kirchner",downloadPdfUrl:"/chapter/pdf-download/10835",previewPdfUrl:"/chapter/pdf-preview/10835",authors:[null],corrections:null},{id:"10840",title:"Formal Methods in Factory Automation",doi:"10.5772/9526",slug:"formal-methods-in-factory-automation",totalDownloads:2648,totalCrossrefCites:3,totalDimensionsCites:4,hasAltmetrics:0,abstract:null,signatures:"Corina Popescu and Jose L. Martinez Lastra",downloadPdfUrl:"/chapter/pdf-download/10840",previewPdfUrl:"/chapter/pdf-preview/10840",authors:[null],corrections:null},{id:"10842",title:"Adaptive Implementation of Discrete Event Control Systems based on Sequential Function Charts",doi:"10.5772/9528",slug:"adaptive-implementation-of-discrete-event-control-systems-based-on-sequential-function-charts",totalDownloads:2626,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:null,signatures:"Ramon Piedrafita and Jose Luis Villarroel",downloadPdfUrl:"/chapter/pdf-download/10842",previewPdfUrl:"/chapter/pdf-preview/10842",authors:[null],corrections:null},{id:"10817",title:"Automated Production Monitoring and Control System Engineering by Combining a Standardized Data Format (CAEX) with Standardized Communication (OPC UA)",doi:"10.5772/9503",slug:"automated-production-monitoring-and-control-system-engineering-by-combining-a-standardized-data-form",totalDownloads:3973,totalCrossrefCites:4,totalDimensionsCites:5,hasAltmetrics:0,abstract:null,signatures:"Miriam Schleipen",downloadPdfUrl:"/chapter/pdf-download/10817",previewPdfUrl:"/chapter/pdf-preview/10817",authors:[null],corrections:null},{id:"10822",title:"Real-Time Obstacle Avoidance Using Potential Field for a Nonholonomic Vehicle",doi:"10.5772/9508",slug:"real-time-obstacle-avoidance-using-potential-field-for-a-nonholonomic-vehicle",totalDownloads:2377,totalCrossrefCites:11,totalDimensionsCites:12,hasAltmetrics:0,abstract:null,signatures:"Hiroaki Seki, Yoshitsugu Kamiya and Masatoshi Hikizu",downloadPdfUrl:"/chapter/pdf-download/10822",previewPdfUrl:"/chapter/pdf-preview/10822",authors:[null],corrections:null},{id:"10841",title:"Developing FPGA-based Embedded Controllers Using Matlab/Simulink",doi:"10.5772/9527",slug:"developing-fpga-based-embedded-controllers-using-matlab-simulink",totalDownloads:9679,totalCrossrefCites:2,totalDimensionsCites:6,hasAltmetrics:0,abstract:"Field Programmable Gate Arrays (FPGAs) are emerging as suitable platforms for implementing embedded control systems. FPGAs offer advantages such as high performance and concurrent computing which makes them attractive in many embedded applications. As reconfigurable devices, they can be used to build the hardware and software components of an embedded system on a single chip. Traditional FPGA design flows and tools, requiring the use of Hardware Description Languages (HDLs), are in a different domain than standard control system design tools such as MATLAB/Simulink. This paper illustrates development of FPGA-based controllers by utilizing popular tools such as MATLAB/Simulink available for the design and development of control systems. The capability of DSP Builder is extended by developing a custom library of control system building blocks that facilitates rapid development of FPGA-based controllers in the familiar Matlab/Simulink environment. As a case study, this paper presents how the tools can be utilized to develop a FPGA-based controller for a laboratory scale air levitation system.",signatures:"T. Barlas and M. Moallem",downloadPdfUrl:"/chapter/pdf-download/10841",previewPdfUrl:"/chapter/pdf-preview/10841",authors:[null],corrections:null},{id:"10832",title:"Model Reference Control of Human-Operated Mobile Robot for Object Transportation",doi:"10.5772/9518",slug:"model-reference-control-of-human-operated-mobile-robot-for-object-transportation",totalDownloads:2056,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:null,signatures:"Naoki Uchiyama and Tatsuhiro Hashimoto",downloadPdfUrl:"/chapter/pdf-download/10832",previewPdfUrl:"/chapter/pdf-preview/10832",authors:[null],corrections:null},{id:"10821",title:"Diagnosis of Intermittent Faults and its dynamics",doi:"10.5772/9507",slug:"diagnosis-of-intermittent-faults-and-its-dynamics",totalDownloads:2215,totalCrossrefCites:1,totalDimensionsCites:2,hasAltmetrics:0,abstract:null,signatures:"A. Correcher, E. Garcia, F. Morant, E. Quiles and L. Rodriguez",downloadPdfUrl:"/chapter/pdf-download/10821",previewPdfUrl:"/chapter/pdf-preview/10821",authors:[null],corrections:null},{id:"10839",title:"Easy-Implementable On-line Identification Method for a First-Order System Including a Time-Delay",doi:"10.5772/9525",slug:"easy-implementable-on-line-identification-method-for-a-first-order-system-including-a-time-delay",totalDownloads:2344,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:1,abstract:"This paper proposes a simple yet effective on-line identification method for a first-order system including a time-delay. This method is based on the Laplace transformation in a real number domain and is able to estimate both coefficients of the first-order system and the time-delay simultaneously. An accuracy of the identification was investigated through a simulation. As a result, precise estimation of the method was confirmed compared to an orthodox on-line estimation technique that utilized a bilinear-model. Moreover, a guideline for a tuning of their parameters used in the method is shown. 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The potential gains provided by emerging markets have attracted significant investor attention which, in turn, has led to substantial capital inflows to these economies. Local currency-denominated sovereign bonds have been the fastest growing market in emerging market space in the past few years. More recently, the global quest for yield in a context of accommodative monetary policies in the advanced economies has created a positive external environment for emerging market bonds. In addition, the secondary market for emerging market local currency debt has also been supported by high interest and amortisation payments. Emerging market bonds are also benefiting from a track record of strong risk-adjusted returns and low correlations with other asset classes. Such characteristics are attractive from a portfolio optimisation perspective. These attributes have also seen considerable attention devoted to analysis of the various risk-return attributes of these markets. In particular, recent empirical literature has focused on the characterisation of the volatility profile of emerging market bond returns. Indeed, the accurate estimation of volatility plays a central role in many applications in finance, including optimal portfolio selection (e.g., diversification strategies), valuation of derivatives (e.g., option pricing) and risk management (e.g., value-at-risk calculation). These applications have motivated an extensive empirical literature on volatility modelling.
While recent empirical literature has focused on the characterisation of the volatility profile of a variety of asset classes; in particular, the long memory properties of these assets, surprisingly little attention has been devoted to the analysis of fixed income markets, especially in emerging markets. The empirical literature on long memory dynamics of fixed income volatility and its implications for portfolio and risk management appears to be limited. Most of the extant literature appears concentrated in the advanced economies. For example, several authors have examined the various aspects of long memory behaviour in interest rates and yield spreads. [1-3] The purpose of this chapter is to augment this line of analysis concerning the long memory attributes of fixed income volatility in emerging market local currency debt market in light of investor interest in the potential alpha generation of these markets, amid wider capital inflows into emerging market bonds as investors search for yield.
This study will focus on government bond markets from Hong Kong, Mexico and South Africa. According to the most recent survey from the Emerging Markets Trading Association (EMTA) these three local currency debt markets are among the most vibrant and actively traded in emerging markets. [4] As a result of their (comparatively high) liquidity, developed institutional frameworks and credible monetary policies, these markets are therefore of interest to investors. Indeed, local currency bond markets have emerged as an important asset class in many emerging markets; a point which becomes salient in the current low-yield environment, where investors targeting high returns and diversification benefits have channelled capital to emerging bond markets such as these.
As a result of regulatory initiatives and various reforms, emerging market local currency sovereign debt markets have has grown rapidly in size and sophistication. According to [4], emerging market debt trading volumes were at USD1.8 trillion in the third quarter of 2011. This represents a 3 percent increase from the USD1.7 trillion reported for the second quarter of 2011. Turnover in local market instruments was at USD1.3 trillion in the third quarter of 2011, (i.e., 76 percent of total reported volume). Mexican and Hong Kong securities were the first and second most frequently traded emerging market debt in the third quarter of 2011 at USD282 billion and USD176 billion, respectively compared to USD136 billion and USD201 billion a year earlier. The next most frequently traded local markets debt were those from Brazil (USD160 billion), South African (USD113 billion) and Turkey (USD69 billion). Analysis is on Hong Kong, Mexico and South Africa due to the availability of data.
Domestic institutional investors are typically the largest investors in local currency bond markets. For example, pension funds tend to have long-term liabilities which are typically funded by investments in long-term investment grade securities that provide a prudent risk-return profile. As a result, the examination of long memory in volatility would appear to be of interest to institutional and other long-term investors. Furthermore, it has been shown that it is important to model the long memory volatility structure when pricing derivative contracts with long maturity. [5] In addition, in order to assess future returns from both active and passive investment strategies or the need for policy intervention, especially over long horizons, it is important to forecast volatility. These applications have motivated an extensive empirical literature on modelling long memory dynamics in asset return data. Analysis of the long-term volatility dynamics of emerging market local currency bonds appear limited. Therefore, this study attempts to help fill this gap by addressing a range of issues relating to the estimation and forecasting of fixed income return volatility especially over long horizons.
Against this background, this paper has three objectives. First, evidence of long memory in volatility within leading emerging fixed income markets is investigated. In particular, the existence of long memory behaviour in the volatility of returns from Hong Kong, Mexico and South Africa are examined which appears to have little or no previous research establishing the existence of its long memory properties. In order to estimate the long memory parameter
In total, the findings of this investigation will provide a range of volatility estimates and forecasts which could potentially inform portfolio management strategies and guide policymaking. In particular, while most empirical studies focus on the United States and other developed markets, recent research has begun to look at emerging markets, however, limited evidence exists with respect to these markets. This analysis contributes to the empirical literature by focusing on various aspects of long memory behaviour in local currency debt markets. The findings from this research complement those in previous studies and may provide an interesting comparison to existing studies.
The rest of the chapter is structured as follows. Section II presents a description of long memory in time series. Section III introduces the data. Section IV presents the empirical methodology and associated results. In particular, this starts with a presentation of the standard GARCH model which is often used to present initial evidence of long memory behaviour. Then the wavelet method and the estimator employed is introduced, along with the relevant findings. This includes a discussion on wavelet analysis, the discrete wavelet transform, the estimator employed and the relevant findings. Section V provides the forecast evaluation techniques used and the out-of-sample forecast results. Section VI considers the evaluation of value-at-risk in the context of the Basle adequacy criteria. Section VII concludes and identifies topics for further research.
Interest in long memory (or long range dependent) processes can be traced to the examination of data in the physical sciences. Formal models with long memory initially pertained to hydrological studies investigating how to regularise the flow of the Nile river in view of its nonperiodic (flooding) cycles. [7] This feature was described as the “Joseph effect” alluding to the biblical reference in which seven years of plenty where to be followed by seven years of famine. [8] In this sense, long memory process concern observations in the remote past that are highly correlated with observations in the distant future. The implications of long memory in financial markets was related to the use of Hurst’s ‘rescaled range’ statistic to detect long memory behaviour in asset return data. [9] It was observed that if security prices display long memory then the arrival of new market information cannot be arbitraged way, which in turn means that martingale models for security prices cannot be derived through arbitrage. As such, long memory processes can be characterised as having fractal dimensions, in the form of non-linear behaviour marked by distinct but nonperiodic cyclical patterns and long-term dependence between distant observations. [10]
A variety of measures have been used to detect long memory in time series. For example, in the time domain, long memory is associated with a hyperbolically decaying autocovariance function. Meanwhile, in the frequency domain, the presence of long memory is indicated by a spectral density function that approaches infinity near the zero frequency; in other words, such series display power at low frequencies. [11] Finally, a pattern of self-similarity in the aggregated sequences of a time series is an indicator of long memory (this refers to the property of a self-similar process, in which, different time aggregates display the same autocorrelation structure). These notions have led several authors to develop stochastic models that capture long memory behaviour, such as the fractionally-integrated I(
Since, non-zero values of the fractional differencing parameter imply dependence between distant observations, considerable attention has been directed to the analysis of fractional dynamics in financial time series data. Indeed, long memory behaviour has been reported in the returns of various asset classes. [15] Against this background, a rapidly expanding set of models has been developed to capture long memory dynamics is asset return data.
The data analysed in this study are obtained from the global bond index (GBI) series for emerging markets (EM) compiled by JP Morgan. In particular, the fixed income data used comprise of daily total returns for Hong Kong, Mexico, and South Africa from December 31, 2001 to April 9, 2012, representing 2571 observations.
More formally, the change in the local bond index
where
Table 1 presents the time series properties of the data using some basic methods. The results of the Augmented Dickey-Fuller (ADF) unit root test offer evidence in favour of stationary fixed income returns. While this test may be deficient in terms of its ability to capture an order of integration that may not be an integer, the finding of stationary bond returns is consistent with those of many previous studies. [15] However, based on the standard normality and Lagrange Multiplier ARCH tests, fixed income return data exhibit non-normality and ARCH effects. [16-17] These non-white noise characteristics of the data motivate estimation of GARCH(1,1) model using the assumption of the Student
Mexico | South Africa | Hong Kong | |
Mean Standard deviation Skewness Kurtosis Normality test ARCH (5) test ARCH (10) test ADF unit root test: Constant Constant & Trend | 0.040496 0.339043 0.538071 20.74158 33829** 64.97** 42.23** -46.72** -46.81** | 0.040533 0.381478 -0.220239 8.738281 3546** 92.71** 53.92** -33.53** -32.88** | 0.017929 0.186277 -0.008431 6.603305 1390** 72.38** 47.92** -61.55** -61.57** |
Description of the Data
The GARCH (1,1) specification comprises a return (or mean) and a variance equation. In particular, the returns generating process can be described by:
where
The GARCH (1,1) model estimates are reported in Table 2. The results confirm the previous findings on the importance of GARCH effects by showing that the GARCH and ARCH terms are all statistically significant. The parameters of the conditional variance equations are all positive and statistically significant. Furthermore, they satisfy the positivity constraint for the GARCH(1,1) model. Furthermore evidence of persistence in variance as measured by the GARCH model is reflected in the magnitude and significance of the ARCH and GARCH terms (indeed, as this sum approaches unity the greater the degree of persistence). Therefore, in order to have an indication of long memory in fixed income return volatility the level of volatility persistence (i.e., α+β) is assessed.
The results indicate that volatility in these markets is very persistent, with the level of volatility persistence being 0.9775 for Mexico, 0.9782 for South Africa and 0.9912 for Hong Kong, which underscores the highly persistent nature of shocks to volatility, which also in turn is suggestive of a long memory component to volatility behaviour in these fixed income markets. The models’ appropriateness has also been checked by applying the Box-Pierce Q statistic test to standardised and squared standardised residuals. Basic diagnostics indicate that the GARCH models are well-specified.
To estimate the long memory parameter
Mexico | South Africa | Hong Kong | |
ω α β Q(5) 1/ Q(5) 2/ Sign bias test Negative size bias test Positive size bias test Joint test | 0.0029 [0.0006]** 0.1245 [0.0166]** 0.8530 [0.0170]** 1.2197 1.8322 1.1775 1.3357 3.1661** 7.7588** | 0.0031 [0.0007]** 0.0756 [0.0118]** 0.9026 [0.0123]** 4.0842 5.4248 2.1147 1.4692 3.3072** 8.3955 | 0.0003 [0.0001]* 0.0510 [0.0089]** 0.9402 [0.0095]** 1.0838 1.3785 2.6833 2.2911 5.6812** 11.3702** |
GARCH Estimates
A wavelet is defined as a wave-like function with an amplitude that oscillates around zero and has a finite or quickly decreasing time support. These functions are well suited to locally approximating variables in time or space as they have the ability to be manipulated by being either ‘stretched’ or ‘squeezed’ so as to mimic the series under investigation. [19] The power of wavelet analysis is that it makes it possible to decompose a time series into its high- and low-frequency components, which are localised in time. Wavelets, also allow the selection of an appropriate trade-off between resolution in the time and frequency domains, while traditional Fourier analysis stresses resolution in the frequency domain at the expense of the time domain. [20] Wavelets therefore provide a convenient and efficient method to analyse complex signals. [21] Wavelet theory is applicable to several subjects. They are especially useful where a signal (e.g. long memory) lasts for a finite time or shows markedly different behaviour in different time periods. These methods, have emerged as a useful tool in the empirical finance literature where long-run and short-run relationships can be distinguished. [22]
A discrete wavelet transform (DWT) is any wavelet transform for which the wavelets are discreetly sampled, as is often the case in econometric analysis. A wavelet transform is a scaling function used to transform a signal into a father
where
In the empirical literature, Haar and Daubechies wavelets represent typical wavelets and have been used in the characterisation of the time series properties of asset return data. The Haar wavelet is the simplest wavelet and provides a basis for studying more complex wavelets. The Haar transform assumes a discrete signal and decomposes the signal into two sub-signals of half its length reflecting the trend process and fluctuations from the trend process.
The data used in this study are discreetly sampled, accordingly, the discrete wavelet transform is used, which permits the generation of the approximation coefficients,
The analysis of fractionally integrated processes through the use of wavelets is based on the result that the detail coefficients of a zero mean long memory process are asymptotically normally distributed with variance
where
To estimate
The regression results of this analysis are presented in Table 3 and 4. The slope coefficient of the regression given in equation (3) provides an estimate,
Volatility series | Identifier | Parameter Estimate | Standard Error | |
Hong Kong | Intercept Slope ( | 1.4167** 0.3423 | 0.1288 0.0310 | 0.9396 |
Mexico | Intercept Slope ( | 1.0344* 0.2363** | 0.2958 0.0281 | 0.9164 |
South Africa | Intercept Slope ( | 1.0151* 0.2679** | 0.1989 0.0664 | 0.9172 |
Estimates of the Long Memory Parameter using the Haar Wavelet
In econometric analysis, it is important to perform diagnostic checks in order to assess the validity of the initial estimates of
Volatility series | Identifier | Parameter Estimate | Standard Error | |
Hong Kong | Intercept Slope ( | 1.0822** 0.3577** | 0.0105 0.0887 | 0.8953 |
Mexico | Intercept Slope ( | 1.5824** 0. 2611* | 0.1996 0.1083 | 0.9076 |
South Africa | Intercept Slope ( | 1.6585** 0.1784** | 0.2210 0.1575 | 0.9412 |
Estimates of the Long Memory Parameter using the Daubechies 4 Wavelet
The analysis indicates robust evidence of long memory behaviour in the return volatility of emerging market debt. Further, wavelet methods provide a robust fit for the data as evidence by the
The evidence accumulated so far suggests that fixed income return volatility in emerging markets follows a long memory process. This, in turn, implies the existence of fractional dynamics in the data which may be exploited to potentially construct improved volatility forecasts, especially over longer forecasting horizons. In order to evaluate the forecasting performance of long memory models (especially over long(er) horizons) versus short memory models (i.e., the GARCH model), the respective data sets are simply split in half and then each model is estimated for all series covering the first part of the sample and then these estimates are used to forecast volatility over the sample period covered by the second half of the data. In this manner, out-of-sample forecast accuracy is evaluated. In addition to calculating the daily forecasts, this study also calculates monthly forecasts using the well-known property that volatility forecasts are additive, such that the sum of five daily volatility forecasts produces the weekly forecasts. And, the summation of weekly forecasts produces monthly forecasts.
In addition to the GARCH and long memory model the RiskMetrics model is also considered for comparative purposes. The RiskMetrics model was popularised by the investment bank JP Morgan and is widely used by financial institutions to model and forecast volatility, especially in the context of the Basle Committee adequacy criteria. This model is essentially an exponentially weighted moving average (EWMA). Under the EWMA, the fitted variance from the model,
where
Two standard symmetric measures are used to evaluate forecast accuracy, namely, the mean absolute error (MAE) and the root mean square error (RMSE). They are defined below:
where
Table 5 reports out-of-sample performance of the estimated models based on the MAE and RMSE forecast error statistics. At the daily level, the results are not unexpected. That is, the GARCH model dominates forecast accuracy for South Africa on the basis of both the MAE and RMSE. For Mexico, the GARCH model dominates forecast performance on the basis of the MAE while the RiskMetrics models delivers the most accuracy when the RMSE is used as a criterion. For Hong Kong the GARCH process is preferred on the basis of the MAE, which surprisingly, the long memory model delivers the best performance when the RMSE is used as a reference. However, in some cases the forecast accuracy of all the models are close; for instance at the daily level the forecast MAE statistics for the GARCH, RiskMetrics and FIGARCH models are virtually indistinguishable. More generally, the findings of GARCH superiority at the daily level are consistent with a wide empirical literature attesting to the forecast superiority of the GACH model at forecasting volatility over daily frequencies or short horizons.
Model | GARCH | RiskMetrics | FIGARCH | |||
Forecast Error Statistic | MAE | RMSE | MAE | RMSE | MAE | RMSE |
Hong Kong | 1.84e-05* | 2.82e-04 | 3.36e-05 | 8.09e-04 | 2.73e-04 | 1.92e-05* |
Mexico | 1.91e-04 | 3.18e-04* | 4.49e-05* | 5.72e-04 | 6.22e-05 | 6.73e-04 |
South Africa | 2.63e-05* | 1.83e-04* | 2.82e-04 | 1.95e-04 | 2.88e-05 | 2.31e-04 |
Daily Forecast Results
At the monthly level (i.e., at a longer horizon) the GARCH model also delivers the most accurate results. This finding is surprising. Long memory implies that widely separated observations are associated with each other which in turn suggests that volatility realizations are connected over long lags. The results shows that at even comparatively longer horizons the GARCH model still delivers the most accurate volatility forecasts. Indeed, Table 6 shows that the forecast MAE statistics for Mexico and South Africa are 3.13e-03 and 3.92e-03, respectively, which are smaller than those from long memory models. The same results holds true for the forecast RMSE error statistics. For Hong Kong fixed returns This result appears to suggest that long memory models while theoretically appealing are not particularly helpful in deriving accurate volatility forecast especially over long horizons.
Model | GARCH | RiskMetrics | FIGARCH | |||
Forecast Error Statistic | MAE | RMSE | MAE | RMSE | MAE | RMSE |
Hong Kong | 4.27e-04 | 2.26e-03* | 2.35e-03* | 4.09e-03 | 4.39e-04 | 4.17e-03 |
Mexico | 3.13e-03* | 4.66e-03 | 5.72e-03 | 4.31e-03* | 4.58e-03 | 6.30e-03 |
South Africa | 3.92e-03* | 4.23e-03* | 4.89e-03 | 4.82e-03 | 4.27e-03 | 4.31e-03 |
Monthly Forecast Results
VaR is a widely used measure to capture the exposure of a portfolio to market risk. The VaR of a position describes the expected maximum loss over a target horizon within a given confidence interval due to an adverse movement in the relevant fixed income yield (or price). VaR is now widely used as an internal risk management tool by financial institutions and as a regulatory measure of risk exposure. [26] In addition, the VaR method is the cornerstone of the 1996 market risk amendment to the Basle Accord (Bank of International Settlements, (BIS), 1996). The Basle Accord prescribes the VaR method in order that financial institutions can meet the capital requirements to cover the market risk they incur in the process of their daily business operations. Under this framework, operational evaluation takes the form of backtesting volatility forecasts and exception reporting.
In particular, the Basle Accord stipulates that for the purpose of calculating regulatory market risk capital it is required that VaR estimates be calculated at the 99 percent probability level using daily data over a minimum sample period of at least one business year (equivalent to 250 trading days) and that these estimates be updated at least every quarter (i.e., 60 trading days). Against this background, the well-known delta-normal specification is employed:
where
In line with the rolling window approach to VaR evaluation mandated by the Basle Committee rules initial volatility forecasts and VaR measures are constructed over intervals of 60 trading days, with the initial estimation sample then rolled forward and the models updated every 60 observations before the next set of volatility forecasts are produced. The first 3-years of data (representing 752 observations) are used for initial model parameter estimation, leaving 1819 observations for volatility forecasting and the construction and evaluation of VaR measures. Specifically, this provides 30 sub-samples of 60 trading days length over which VaR is assessed. This assessment is conducted through appraisal of the out-of-sample VaR failure rates associated with VaR measures constructed using the forecast values of those volatility measures. The assessment of VaR performance is conducted through appraisal of the ‘out-of-sample’ VaR failure rates associated with VaR measures constructed using the forecast values derived from the GARCH, RiskMetrics and long memory model. The focus on the ‘out-of-sample’ failure rates is motivated by the requirements of risk managers, who obtain VaR estimates in real time and must use parameters obtained from an already observed sample in order to evaluate the risks associated with current and future random movements in risk factors. As a result, credible test of VaR construction methods under alternative volatility forecasting models is their performance outside the sample used to estimate the underlying parameters.
Table 7 reports the out-of-sample VaR failure rates. The results are very diverse and highlight that in many of the markets considered the forecasting model that minimises the percentage number of daily VaR exceedances is sensitive to the specification of the probability level. When the Basle Committee rules are applied (i.e., the 99 percent probability level) the results indicate that the GARCH and RiskMetrics that provide the exceedance-minimising method for the fixed income markets considered. At the 99 percent probability level the long memory model is the generally the weakest performer. However, in the case of Hong Kong and South Africa the long memory model is second best model in terms of delivering accurate VaR measures. In addition, it is important to note that in many cases is level of accuracy between the various models is close as reflected by the closeness of the VaR failure rates. At the 97.5 and 95 percent probability levels model performance is more varied with all models demonstrating varied degrees of accuracy. As a generalization, these results are mixed but the evidence suggests that at the Basle prudential level the simpler models help in providing improved VaR estimates that minimise occasions when the minimum capital requirement identified by the VaR methodology would have fallen short of actual trading losses.
Hong Kong | Mexico | South Africa | |||||||
model | 99% | 97.5% | 95% | 99% | 97.5% | 95% | 99% | 97.5% | 95% |
RM GARCH FIGARCH | 0.0178* 0.0192 0.0185 | 0.0347 0.0256* 0.0391 | 0.0224* 0.0536 0.0493 | 0.0154 0.0152* 0.0179 | 0.0326 0.0312 0.0297* | 0.0378 0.0356* 0.0521 | 0.0224 0.0192* 0.0222 | 0.0311 0.0286* 0.0303 | 0.0218* 0.0261 0.0323 |
VaR Failure Rates – Out-of-Sample
Recent empirical evidence concerning the nature of volatility dynamics in fixed income markets suggests the existence of a long memory component. Since volatility in fixed income returns is an important aspect of portfolio management it is essential to accurately characterise the time series properties of fixed income volatility especially in the context of emerging markets where local currency-denominated sovereign bonds have been the fastest growing market in recent years. Accordingly, the objective of this analysis was to examine the existence of long memory behaviour in the volatility structure of total return indices for the local currency bond markets of Hong Kong, Mexico and South Africa. Against this background, the long memory parameter is estimated using methods based on wavelets, which have gained prominence in recent years. Furthermore, this study has compared and evaluated the performance of a long memory model versus a standard volatility models (the ubiquitous GARCH and RiskMetrics processes) in order to evaluate their power in delivering accurate volatility forecasts over long(er) horizons in an out-of-sample setting. This endeavour is motivated by recognition of the importance of accurate volatility forecasts in a wide range of applications, including tactical and strategic decision making and the limited empirical evidence available to date for emerging fixed income markets. Then, the performance of the standard GARCH, RiskMetrics and FIGARCH models are evaluated in the context of value-at-risk (VaR) estimation given the Basle regulatory framework.
The main findings of this research are threefold. First, evidence of long memory is conclusively demonstrated in emerging market local currency sovereign debt markets. In addition, to counteract the possibility of finding spurious evidence of long memory a variety of wavelet forms are considered. The findings from these tests are complementary and therefore suggest that the finding of long memory is not spurious. Second, the presence of a long memory structure in the volatility of these fixed income markets suggests volatility observations in the recent past and the remote past are associated with each other. Since the series realisations are not independent over time then past volatility may potentially be exploited to predict future volatility, especially over long horizons. Accordingly, the out-of-sample forecasting performance of the long memory model and the standard GARCH and RiskMetrics models are compared. While, none of the estimated models consistently outperforms the others, a key generalisation can be made. In particular, on the basis of the forecast MAE and RMSE statistics it is shown that the information content of long memory models does not consistently generate improved volatility forecasts, especially over long horizons, relative to the standard GARCH model. Indeed, the GARCH model generally provides the most accurate forecasts at the monthly horizon. With respect to VaR estimation, the results show that both the standard GARCH and RiskMetrics models generally deliver more accurate VaR measures relative to the long memory process.
These findings have three important implications. First, the exploitation of long memory models based on wavelet analysis may not have great relevance in the context of emerging market debt in terms of delivering superior forecast performance. Second, the existence of a long memory structure in volatility is not an essential condition for the derivation of accurate volatility forecasts at any time horizon, especially over a long horizon. Indeed, this research suggests that long memory models appear to be of limited practical forecast value, especially over long horizons, for Hong Kong, Mexico and South Africa. Put differently, the computational complexity of long memory modelling is not commensurate with the benefits (in terms of forecast power). Third, the results of the VaR estimation may provide guidance on more effective prudential standards for operational risk measurement and, as result, may help ensure adequate capitalisation and reduce the probability of financial distress. The results highlight the importance of using out-of-sample forecasting techniques and the stipulated probability level for the identification of methods that minimise the occurrence of VaR exceptions. Standard models – RiskMetrics and GARCH – that are already widely used by market participants are generally shown to outperform the more computationally intensive wavelet-derived FIGARCH model in estimating VaR across the probability levels considered.
In sum, this research has evaluated the long memory properties of return volatility in fixed income markets. This paper also complements the literature on long memory models and the forecast performance of these models that has attracted interest in other asset classes. In addition, the results of this study may potentially be used to inform portfolio and risk analysis. In particular, it is shown that in the context of VaR estimation existing models based on the GARCH and/or RiskMetrics process are more accurate (and simpler) than their long memory counterpart. Some caveats to these results exist, however. First, squared returns provide a noisy proxy for the ‘true’ volatility. In the case of this analysis, data constraints limited alternative options. However, future research may find that the application of realised variance may produce more accurate forecasts. Second, future research may also consider exploring the relevance of other long memory models, for example, models with asymmetric effects given that market volatility is often reported as being ‘directional’, i.e., volatility is higher in a down – than an upmarket.
Iron is one of the most abundant elements in the earth’s crust. It always coexists with metals in the ore, mainly exists in the form of hematite, magnetite and muscovite on the surface of particles or in the inclusions inside crystals [1]. In hydrometallurgy, iron, although is converted into insoluble precipitates and removed in advance by sulfation roasting, soda roasting, acid leaching, etc. during ore pretreatment, still inevitably goes to the aqueous solution with the dissolution of the target metal during the leaching process [2, 3, 4]. The classical methods for removing iron in the leaching solution are precipitation, extraction, ion exchange, displacement, and electrowinning [4]. The commonly used method is the precipitation method, which separates iron ions by converting to iron precipitation compounds. According to the different iron precipitation compounds, it can be divided into jarosite [5, 6], hematite [7], iron(III) oxide-hydroxide [8] and goethite [9, 10] method, etc. The jarosite method produces a large amount of low-grade iron-bearing slag in the application, which is difficult to handle, consumes a large amount of sulfate, and causes certain environmental problems [5, 6]; the hematite method needs to be carried out under high temperature and pressure, which consumes large energy and high CAPEX (capital expenditure) [7]. The filtration efficiency of Fe(OH)3 colloid precipitation method is low, and it is easy to adsorb a large amount of other valuable metals, causing large metal loss [8].
\nThe goethite method is widely used in hydrometallurgical plants for zinc, copper and nickel as the main process for removing iron because of its low CAPEX and environmentally friendly products [9, 10]. In order to ensure the effect and efficiency of iron removal, the goethite process must strictly control the concentration of Fe3+ below 1 g/L, and thus developed the two commonly used processes - VM method and EZ method [8, 9, 11]. The former firstly reduces all the iron ions to Fe2+, and then slowly oxidizes the Fe2+ to Fe3+ under hydrolysis conditions to control the content of Fe3+ [9], and the latter slowly adds the concentrated pressure leachate containing Fe3+ in the precipitation vessel with addition rate of less than the Fe3+ hydrolysis rate, thereby forming goethite precipitation [11]. The pH in goethite process is common lower than 4.0, and calcium hydroxide or calcium carbonate is usually used as neutralizer, which will result in a large amount of calcium sulfate mixed with the goethite residue [12]. These mixed residues reduce the filtration efficiency and cause the loss of valuable metals such as Zn and Ni [5, 13, 14]. In addition, the residue mixture accumulated in the tailings pond contains heavy metals such as Pb, As, and Cr, which causes pollution of local water and soil. Therefore, improving filtration performance and reducing the loss of valuable metals are two problems that need to be solved urgently in the traditional goethite precipitation method.
\nThis article summarizes the new improvements in iron removal by precipitation methods in recent years, and on this basis, proposes a novel iron removal process - magnetic seeding and separation. A core-shell structure is formed by precipitating and growing iron on the magnetic seeds surface, and achieves high-efficiency solid-liquid separation by magnetic separation. The new process remarkably reduces the loss of valuable metals in iron removal. Magnetic seeding and separation processes have not only been successfully used in the removal of iron from hydrometallurgical leachate, but also shown good application prospects in wastewater and soil pollution treatment.
\nMagnetic flocculation and separation based on the magnetic difference of materials can easily separate magnetic solids from mixtures. It shows higher selectivity and efficiency than centrifugation and filtration, and has been widely used in water treatment, biotechnology and minerals separation [15, 16, 17, 18]. As is shown in \nFigure 1\n, Han et al. [3] studied the feasibility of magnetite precipitation in the hydrometallurgical nickel leaching solution. Under lower oxidation potential, at pH 2.0–2.2 and 90–100°C, the iron ions in the leachate may slowly oxidize and partially precipitate in the form of magnetite. Magnetic flocculation and separation can effectively separate the precipitate from the solution. Unfortunately, the iron precipitation from solution is still dominated by goethite, the magnetite composition is relatively small, and it is difficult to truly achieve effective magnetic separation in industrial applications. But this research of magnetite process of iron removal provides other new ideas of magnetic separation.
\nPotential/pH diagram for Fe-H2O system at 100°C.
The goethite process can be divided into four stages: (a) hydrolysis to monomers and dimers; (b) the reversible stage involving rapid growth to small polymers; (c) formation of slowly reacting large polymers; and (d) precipitation of a solid phase [19, 20]. The goethite precipitation system is a complex system, and the presence and content of different components and iron phases have a greater impact on the precipitation and filtration performance of goethite. As shown in \nFigure 2\n, the pH and temperature conditions of the sulfate-containing solution determine the existence and content of different iron phases such as hematite, goethite, iron hydroxide and hydroxyl salt [21]. The goethite residues that cause filtration difficulties and metal loss are composed of amorphous iron phase, six-line ferrihydrite, poor crystalline goethite, solid solution jarosite phase and silica [2, 22]. Therefore, the crystallinity, size and content of the goethite particles can be controlled by adjusting the pH, thereby improving the separation performance and the loss of valuable metals.
\nTemperature and pH conditions for the precipitation of hematite, goethite, ferric hydroxide, and hydroxy salts (including jarosites) from 0.5 M ferric sulfate solution [
Yue and Han [23] study that as the pH value decreases from 5.0 to 2.0, as shown in \nFigure 3\n, the crystallinity of goethite decreases, the goethite particles tend to agglomerate, the particle size increases significantly, and the filterability of the precipitate improves. Nickel is lost in the iron precipitate by being incorporated into the crystal lattice and adsorbed on the surface of the goethite particles, and the nickel adsorption loss are related to the specific surface area of the goethite particles. When goethite is in an intermediate transition state at low pH (2.5–3.3), which is between the crystalline state and the colloidal state, the loss of nickel is the least. However, the improvement by only adjusting the pH of the goethite precipitation process is minimal. Chang et al. [24] carefully reduced the pH from 4.0 to 2.5, and the loss of nickel is only reduced by about 10% in the iron precipitation. Moreover, it is not realistic to achieve such detailed condition control in actual industrial applications.
\n(a) SEM images of the goethite precipitate at different pHs and (b) pH effect for the nickel loss, the crystallinity, and the specific surface area of the precipitate [
The traditional goethite precipitation method needs to overcome high barriers to the formation of crystals, and often requires a few days of reaction time. The amorphous iron phase appears at this stage, making precipitation separation difficult. Seed induced crystallization can make crystals precipitate and crystallize from the solution at lower solution saturation, pH value and temperature, and has been widely used in the preparation and production of drugs and nanomaterials [26, 27, 28, 29]. Han [30] choose natural limonite as the seed crystal of goethite and induce crystallization to improve the problem of poor filterability at the low pH goethite precipitate. As is shown in \nFigure 4\n, by adding limonite seeds, the particle size of the goethite precipitate is significantly increased. The goethite particles in the particle size range of 37–74 μm have the largest yield and the smallest specific surface area, which can result iron precipitates with a nickel grade of <1%. However, the reduction of metal loss and improvement of filterability are difficult to achieve at the same time by pH control and induced crystallization, one of them must be sacrificed. The intermediate transition state goethite with good filtration performance and minimum metal loss is difficult to accurately induce formation in the actual field industry. It is a need to find other ideas to achieve qualitative progress.
\nThe specific surface area and the nickel grade of iron precipitates with limonite seeds in different size ranges (2 g/L limonite seeds, pH 2.1–2.5, 85°C) [
Han et al. [25, 31, 32] combined seed induced crystallization and magnetic separation, and proposed a novel magnetic seeding and separation process, as shown in \nFigure 5\n. Before the iron is precipitated as goethite, fine-grained maghemite or magnetite particles are added to the leaching solution to make the goethite precipitate and grow on the surface of the magnetic particles, thereby avoiding mixing with the calcium sulfate precipitation in the solution. The iron precipitates on the surface of the goethite to form large magnetic particles with a core-shell structure, and the precipitates are efficiently settled and separated by magnetic separation. The results show that the iron content in the dry iron residue is more than 52% and the Ni content is less than 0.6%, which can be used in industrial applications to deal with a large amount of iron precipitation. After the calcium sulfate precipitation is roasted, 99% of S and As can be removed, and the roasting residue can be respectively used as raw materials for ironmaking and building materials.
\nThe process of iron precipitation on the magnetic seeds and the magnetic flocculation in magnetic field [
Yue et al. [31] applied magnetic iron seeding and separation to separate goethite from calcium sulfate in zinc leaching with maghemite fine particles as carrier. As is shown in \nFigure 6\n, the magnetic goethite-maghemite aggregates were separated effectively from calcium sulfate precipitates by magnetic drum separator, and 90% of Fe and Ca is respectively recovered in two corresponding products. Roasting goethite precipitate with coal powder under the optimum conditions removed 99% of S and As. Goethite products can be directly used in the ironmaking industry, and calcium sulfate precipitation can also be used to produce cement and building materials.
\nSchematic illustration of magnetic separation and production of desired goethite and gypsum product [
Yue et al. [32] establish the surface complex and precipitation model of goethite on magnetite and maghemite magnetic nanoparticles, as shown in \nFigure 7\n. The formation of Fe (III) surface complexes are directly related to the nucleation and precipitation of goethite on the solid surfaces of the two magnetic nanoparticles. The more polynuclear surface complexes produced on the particle surface, the more precipitation of heterogeneous forms. Fundamentally, it is possible to screen out the best material as the crystal nucleus to separate goethite from calcium sulfate or other heterogeneous precipitation.
\nSurface precipitation model modeling (a) of Fe3+ adsorption/precipitation on magnetite and maghemite with corresponding magnetic separation of goethite, images of the suspensions in a magnetic field with 2 g/L (b) magnetite and (c) maghemite NPs, and SEM images of goethite precipitates with (d) magnetite and (e) maghemite NPs [
The Cr-bearing electroplating sludge is produced from the treatment of Cr wastewater and metallurgical processes [33, 34, 35, 36]. It contains excessive amounts of heavy metals, such as Cr, Fe, Ni, Cu, Pb and Zn, or potential dioxin pollutants [37, 38], therefore must be treated before stacking. Many methods have been applied to recover Cr from the acid leaching solution of electroplating sludge, such as electrochemical precipitation (ECP) [39], selective extraction [35, 40], adsorption or biosorption [41, 42, 43, 44] and Cr-Fe coprecipitation [45, 46, 47, 48]. Compared with other methods, recovering Cr by Cr-Fe coprecipitation is simple, economical and practical for industrial applications. In addition, the advance coprecipitation of Fe and Cr can avoid their interference on the recovery of Ni, Cu and Zn.
\nYue et al. [49] use the novel magnetic seeding and separation process to recover Cr(III) and Fe(II) synchronously by forming the Cr(III)-Fe(III) coprecipitates on the surface of maghemite (γ-Fe2O3) fine particles. The active hydroxide radicals on the surface of magnetic seeds induce the nucleation and growth of goethite, which results in enhanced Cr (III)-Fe(III) coprecipitation. As shown in \nFigure 8\n, the maghemite particles, served as the crystal nuclei, could induce the formation of the core-shell structured Cr (III)-Fe(III) coprecipitates on its surface and accelerate the sedimentation of the coprecipitates in the magnetic field. The results of the two-stage coprecipitation showed that the total recoveries of Cr and Fe were 96.17 and 99.39%, respectively, and the grades of Ni, Cu, and Zn in the precipitates were 0.41, 0.38, and 0.22%, respectively. The obtained coprecipitates can be recycled as the feed material of chromium smelting after heat treatment. This method is simple and efficient for high-concentration Cr3+ solution treatment, which is beneficial for the sustainable development of resources and environment.
\nSEM images of the Cr(III)-Fe(III) coprecipitates without maghemite fine particles (a) and with maghemite fine particles (b), respectively; scheme (c) of the formation of γ-Fe2O3/Crx Fe1-xOOH with core-shell structure [
Arsenic (As) is contained in most metal deposits, and therefore a large amount of arsenic-containing wastewater, flue gas and residues will be produced in mineral processing and smelting, posing a huge threat to the environment [50, 51, 52]. Commonly used methods for removing arsenic from solution include precipitation, electrocoagulation, ion exchange, membrane technology and adsorption [53, 54, 55, 56]. In order to remove arsenic and recover valuable metals at the same time, these methods all require acid leaching of the waste, which will produce highly toxic and deadly arsine gas [54, 57]. As is shown in \nFigure 9(a)\n, Yue [58] developed a safer alkaline leaching method - oxidation alkali leaching of the wastes to transform arsenic compounds into arsenate (\n
(a) Flow diagram of the comprehensive treatment of the arsenic alkali residue and (b) arsenic removal from arsenic alkali solution with different HFG samples synthesized at pH 3(I), 7(II), and 11(III) [
There are a large number of reports that iron oxides have excellent adsorption and precipitation effects on heavy metal ions impurities in aqueous solutions, such as CrU and As. Garcı́a-Sanchez et al. [59, 60] found that goethite has a special adsorption effect and capacity for As ions. Wei Jiang [61] considers that arsenic [\n
Phosphorus and starch reportedly are the main wastewater contaminants that are difficult to remove efficiently [63, 64]. When the phosphorus concentration in water exceeds 0.02 mg/L, phosphorus becomes a polluting element and causes eutrophication of water bodies [65, 66, 67]. Starch is a commonly used and cheap material, widely used in many chemical and material industries, but it produces high concentration of organic wastewater, which will affect the environment [68, 69, 70]. Therefore, phosphate and starch removal from wastewater has become the focus of many studies. The main phosphate and starch removal methods are similar, such as chemical precipitation [71, 72, 73, 74], biological methods [75, 76, 77, 78, 79] and adsorption techniques [80, 81, 82, 83]. Among them, Chemical precipitation and adsorption technology is commonly used in wastewater treatment due to the simple operation with low cost and large processing capacity compared to other methods [84, 85, 86]. However, chemical precipitation inevitably produces a large amount of fine precipitation and suspended solids, which seriously affect the sedimentation and filtration efficiency [84, 87]. And the adsorbents currently used in adsorption technology, such as activated carbon [70, 88], silica gel [89, 90], membranes [91, 92, 93], etc., have high production costs and poor adsorption performance, which greatly limits the adsorption effect and industrial applications.
\nMagnetic flocculation is an effective way to remove ultrafine suspended solids in water treatment [94, 95]. It adds magnetic seeds to the aqueous solution to form magnetic flocs with the ultrafine suspended solids in the wastewater, and then passes through a magnetic separator to achieve rapid precipitation and separation [3, 95, 96]. The combination of magnetic flocculation and chemical precipitation can make up for the shortcomings of ultrafine suspended solids and low separation efficiency of chemical precipitation. Magnetic flocculation has been widely used to treat wastewater with high pollution concentration [71], high turbidity [96] and high chemical oxygen demand (COD) [97]. It is worth noting that in many studies, iron-bearing minerals have shown the characteristics of removing phosphorus from aqueous solutions [98, 99]. The iron-bearing minerals can be coordinated with phosphate and therefore have the potential to be used as adsorption materials for phosphorus and starch in wastewater [100, 101].
\nDu et al. [102, 103] combined the magnetic flocculation technology with iron-containing materials to prepare porous magnetic seeds with core-shell structure, which achieved simultaneous removal of starch and phosphate in wastewater. As shown in \nFigure 10\n, the core-shell magnetic seeds prepared by sulfation roasting of fine magnetite particles have a porous α-Fe2O3 structure on the surface, and the specific surface area is three times larger [103, 104, 105, 106]. As shown in \nFigure 10\n, the phosphate and starch in the wastewater can be adsorbed on magnetic seeds surface, and then separated from the wastewater by magnetic separation. The phosphorus and starch content in the wastewater are reduced to 1.51 and 9.51 mg/L, respectively, and the removal rate reaches more than 75% [102].
\nThe chemical precipitation and magnetic flocculation of removed hydroxyapatite contaminants [
The iron removal method of the hydrometallurgical leachate is still dominated by the goethite process. The goethite process faces the disadvantages of high loss rate of valuable metals and difficulty in separation and filtration, which must be solved to get qualitative improvement. Careful adjustment of the pH value can help reduce metal loss, and inducing crystallization can increase the crystallinity of goethite and improve the separation and filtration efficiency. However, both methods can only focus on solving one of the problems and cannot reduce loss and promote filtration at the same time. The magnetite produced during the precipitation (crystallization) process opened a new path for magnetic separation, while the magnetite method is currently limited to laboratory research. In the present paper, the authors combined the goethite precipitation (crystallization) method with magnetic seed separation technology and developed a novel route. Goethite precipitates on the surface of the external magnetic seeds to form core-shell structured particles, which are efficiently separated by magnetic separation, and at the same time solve the two major problems of the traditional goethite process. This new method also shows advantages in the fields of arsenic and chromium removal from the leachate, phosphorus, and starch removal from wastewater and other fields. Goethite is the most common and stable crystalline iron oxide in soil and sediment. We expect that the goethite method combined with magnetic seed separation technology will show better results in the removal of organic dyeing, heavy metal ions, anions in wastewater and soil, and the adsorption and passivation of chemicals, nutrients, and harmful compounds in environments.
\nThis work was supported by the Hunan Natural Science Foundation of China (No. 2020JJ5727), Innovation Driven Plan of Central South University (No. 2018CX036), National 111 Project (No. B14034), and Collaborative Innovation Center for Clean and Efficient Utilization of Strategic Metal Mineral Resources, Key Laboratory of Hunan Province for Clean and Efficient Utilization of Strategic Calcium-containing Mineral Resources (No. 2018TP1002).
\nIntechOpen - where academia and industry create content with global impact
",metaTitle:"Team",metaDescription:"Advancing discovery in Open Access for the scientists by the scientist",metaKeywords:null,canonicalURL:"page/team",contentRaw:'[{"type":"htmlEditorComponent","content":"Our business values are based on those any scientist applies to their research. We have created a culture of respect and collaboration within a relaxed, friendly and progressive atmosphere, while maintaining academic rigour.
\\n\\nCo-founded by Alex Lazinica and Vedran Kordic: “We are passionate about the advancement of science. As Ph.D. researchers in Vienna, we found it difficult to access the scholarly research we needed. We created IntechOpen with the specific aim of putting the academic needs of the global research community before the business interests of publishers. Our Team is now a global one and includes highly-renowned scientists and publishers, as well as experts in disseminating your research.”
\\n\\nBut, one thing we have in common is -- we are all scientists at heart!
\\n\\nSara Uhac, COO
\\n\\nSara Uhac was appointed Managing Director of IntechOpen at the beginning of 2014. She directs and controls the company’s operations. Sara joined IntechOpen in 2010 as Head of Journal Publishing, a new strategically underdeveloped department at that time. After obtaining a Master's degree in Media Management, she completed her Ph.D. at the University of Lugano, Switzerland. She holds a BA in Financial Market Management from the Bocconi University in Milan, Italy, where she started her career in the American publishing house Condé Nast and further collaborated with the UK-based publishing company Time Out. Sara was awarded a professional degree in Publishing from Yale University (2012). She is a member of the professional branch association of "Publishers, Designers and Graphic Artists" at the Croatian Chamber of Commerce.
\\n\\nAdrian Assad De Marco
\\n\\nAdrian Assad De Marco joined the company as a Director in 2017. With his extensive experience in management, acquired while working for regional and global leaders, he took over direction and control of all the company's publishing processes. Adrian holds a degree in Economy and Management from the University of Zagreb, School of Economics, Croatia. A former sportsman, he continually strives to develop his skills through professional courses and specializations such as NLP (Neuro-linguistic programming).
\\n\\nDr Alex Lazinica
\\n\\nAlex Lazinica is co-founder and Board member of IntechOpen. After obtaining a Master's degree in Mechanical Engineering, he continued his Ph.D. in Robotics at the Vienna University of Technology. There, he worked as a robotics researcher with the university's Intelligent Manufacturing Systems Group, as well as a guest researcher at various European universities, including the Swiss Federal Institute of Technology Lausanne (EPFL). During this time he published more than 20 scientific papers, gave presentations, served as a reviewer for major robotic journals and conferences and, most importantly, co-founded and built the International Journal of Advanced Robotic Systems, the world's first Open Access journal in the field of robotics. Starting this journal was a pivotal point in his career since it proved to be the pathway to the foundation of IntechOpen with its focus on addressing academic researchers’ needs. Alex personifies many of IntechOpen´s key values, including the commitment to developing mutual trust, openness, and a spirit of entrepreneurialism. Today, his focus is on defining the growth and development strategy for the company.
\\n"}]'},components:[{type:"htmlEditorComponent",content:"Our business values are based on those any scientist applies to their research. We have created a culture of respect and collaboration within a relaxed, friendly and progressive atmosphere, while maintaining academic rigour.
\n\nCo-founded by Alex Lazinica and Vedran Kordic: “We are passionate about the advancement of science. As Ph.D. researchers in Vienna, we found it difficult to access the scholarly research we needed. We created IntechOpen with the specific aim of putting the academic needs of the global research community before the business interests of publishers. Our Team is now a global one and includes highly-renowned scientists and publishers, as well as experts in disseminating your research.”
\n\nBut, one thing we have in common is -- we are all scientists at heart!
\n\nSara Uhac, COO
\n\nSara Uhac was appointed Managing Director of IntechOpen at the beginning of 2014. She directs and controls the company’s operations. Sara joined IntechOpen in 2010 as Head of Journal Publishing, a new strategically underdeveloped department at that time. After obtaining a Master's degree in Media Management, she completed her Ph.D. at the University of Lugano, Switzerland. She holds a BA in Financial Market Management from the Bocconi University in Milan, Italy, where she started her career in the American publishing house Condé Nast and further collaborated with the UK-based publishing company Time Out. Sara was awarded a professional degree in Publishing from Yale University (2012). She is a member of the professional branch association of "Publishers, Designers and Graphic Artists" at the Croatian Chamber of Commerce.
\n\nAdrian Assad De Marco
\n\nAdrian Assad De Marco joined the company as a Director in 2017. With his extensive experience in management, acquired while working for regional and global leaders, he took over direction and control of all the company's publishing processes. Adrian holds a degree in Economy and Management from the University of Zagreb, School of Economics, Croatia. A former sportsman, he continually strives to develop his skills through professional courses and specializations such as NLP (Neuro-linguistic programming).
\n\nDr Alex Lazinica
\n\nAlex Lazinica is co-founder and Board member of IntechOpen. After obtaining a Master's degree in Mechanical Engineering, he continued his Ph.D. in Robotics at the Vienna University of Technology. There, he worked as a robotics researcher with the university's Intelligent Manufacturing Systems Group, as well as a guest researcher at various European universities, including the Swiss Federal Institute of Technology Lausanne (EPFL). During this time he published more than 20 scientific papers, gave presentations, served as a reviewer for major robotic journals and conferences and, most importantly, co-founded and built the International Journal of Advanced Robotic Systems, the world's first Open Access journal in the field of robotics. Starting this journal was a pivotal point in his career since it proved to be the pathway to the foundation of IntechOpen with its focus on addressing academic researchers’ needs. Alex personifies many of IntechOpen´s key values, including the commitment to developing mutual trust, openness, and a spirit of entrepreneurialism. Today, his focus is on defining the growth and development strategy for the company.
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His studies in robotics lead him not only to a PhD degree but also inspired him to co-found and build the International Journal of Advanced Robotic Systems - world's first Open Access journal in the field of robotics.",institutionString:null,institution:{name:"TU Wien",country:{name:"Austria"}}},{id:"441",title:"Ph.D.",name:"Jaekyu",middleName:null,surname:"Park",slug:"jaekyu-park",fullName:"Jaekyu Park",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/441/images/1881_n.jpg",biography:null,institutionString:null,institution:{name:"LG Corporation (South Korea)",country:{name:"Korea, South"}}},{id:"465",title:"Dr.",name:"Christian",middleName:null,surname:"Martens",slug:"christian-martens",fullName:"Christian Martens",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Rheinmetall (Germany)",country:{name:"Germany"}}},{id:"479",title:"Dr.",name:"Valentina",middleName:null,surname:"Colla",slug:"valentina-colla",fullName:"Valentina Colla",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/479/images/358_n.jpg",biography:null,institutionString:null,institution:{name:"Sant'Anna School of Advanced Studies",country:{name:"Italy"}}},{id:"494",title:"PhD",name:"Loris",middleName:null,surname:"Nanni",slug:"loris-nanni",fullName:"Loris Nanni",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/494/images/system/494.jpg",biography:"Loris Nanni received his Master Degree cum laude on June-2002 from the University of Bologna, and the April 26th 2006 he received his Ph.D. in Computer Engineering at DEIS, University of Bologna. 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The main objective of the DSS is to improve the decision‐making processes through visualization tools and simulation of real cases in the EPDS, in order to allow better planning in the short, medium, and long term. Therefore, the DSS helps managers and decision‐makers to reduce maintenance and operational costs, to improve system reliability, and to analyze new scenarios and conditions for system expansion planning. First, we introduce the key challenges faced by the decision‐makers in the planning and operation of maintenance and customer services in EPDS. Next, we discuss the benefits and the requirements for the DSS design and development, including use cases modeling and the software architecture. Afterwards, we present the capabilities of the DSS and discuss important decisions made during the implementation phases. We conclude the chapter with a discussion about the obtained results, pointing out the possible enhancements of the DSS, future extensions, and new use cases that may be addressed.",book:{id:"6024",slug:"system-reliability",title:"System Reliability",fullTitle:"System Reliability"},signatures:"Carlos Henrique Barriquello, Vinícius Jacques Garcia, Magdiel\nSchmitz, Daniel Pinheiro Bernardon and Júlio Schenato Fonini",authors:[{id:"180154",title:"Dr.",name:"Daniel",middleName:"P",surname:"Bernardon",slug:"daniel-bernardon",fullName:"Daniel Bernardon"},{id:"180657",title:"Dr.",name:"Vinicius Jacques",middleName:"Jacques",surname:"Garcia",slug:"vinicius-jacques-garcia",fullName:"Vinicius Jacques Garcia"},{id:"203699",title:"Dr.",name:"Carlos",middleName:null,surname:"Barriquello",slug:"carlos-barriquello",fullName:"Carlos Barriquello"},{id:"206560",title:"Mr.",name:"Magdiel",middleName:null,surname:"Schmitz",slug:"magdiel-schmitz",fullName:"Magdiel Schmitz"},{id:"206562",title:"BSc.",name:"Júlio",middleName:null,surname:"Schenato Fonini",slug:"julio-schenato-fonini",fullName:"Júlio Schenato Fonini"}]},{id:"66913",doi:"10.5772/intechopen.85571",title:"Reliability Evaluation of Power Systems",slug:"reliability-evaluation-of-power-systems",totalDownloads:2046,totalCrossrefCites:3,totalDimensionsCites:7,abstract:"Reliability evaluation of electric power systems is an essential and vital issue in the planning, designing, and operation of power systems. An electric power system consists of a set of components interconnected with each other in some purposeful and meaningful manner. The object of a reliability evaluation is to derive suitable measures, criteria, and indices of reliable and dependable performance based on component outage data and configuration. For evaluating generated reliability, the components of interest are the generating units and system configuration, which refer to the specific unit(s) operated to serve the present or future load. The indices used to measure the generated reliability are probabilistic estimates of the ability of a particular generation configuration to supply the load demand. These indices are better understood as an assessment of system-wide generation adequacy and not as absolute measures of system reliability. The indices are sensitive to basic factors like unit size and unit availability and are most useful when comparing the relative reliability of different generation configurations. The system is deemed to operate successfully if there is enough generation capacity (adequate reserve) to satisfy the peak load (maximum demand). Firstly, generation model and load model are convolved (mutually combined) to yield the risk of supply shortages in the system. Secondly, probabilistic estimates of shortage risk are used as indices of bulk power system reliability evaluation for the considered configuration.",book:{id:"7687",slug:"reliability-and-maintenance-an-overview-of-cases",title:"Reliability and Maintenance",fullTitle:"Reliability and Maintenance - An Overview of Cases"},signatures:"Abdullah M. Al-Shaalan",authors:[{id:"274935",title:"Prof.",name:"Abdullah",middleName:"Mohammed",surname:"Al-Shaalan",slug:"abdullah-al-shaalan",fullName:"Abdullah Al-Shaalan"}]},{id:"55938",doi:"10.5772/intechopen.69286",title:"Imperfect Maintenance Models, from Theory to Practice",slug:"imperfect-maintenance-models-from-theory-to-practice",totalDownloads:2206,totalCrossrefCites:3,totalDimensionsCites:6,abstract:"The role of maintenance in the industrial environment changed a lot in recent years, and today, it is a key function for long-term profitability in an organization. Many contributions were recently written by researchers on this topic. A lot of models were proposed to optimize maintenance activities while ensuring availability and high-quality requirements. In addition to the well-known classification of maintenance activities—preventive and corrective—in the last decades, a new classification emerged in the literature regarding the degree of system restoration after maintenance actions. Among them, the imperfect maintenance is one of the most studied maintenance types: it is defined as an action after which the system lies in a state somewhere between an “as good as new” state and its pre-maintenance condition “as bad as old.” Most of the industrial companies usually operate with imperfect maintenance actions, even if the awareness in actual industrial context is limited. On the practical definition side, in particular, there are some real situations of imperfect maintenance: three main specific cases were identified, both from literature analysis and from experience. Considering these three implementations of imperfect maintenance actions and the main models proposed in the literature, we illustrate how to identify the most suitable model for each real case.",book:{id:"6024",slug:"system-reliability",title:"System Reliability",fullTitle:"System Reliability"},signatures:"Filippo De Carlo and Maria Antonietta Arleo",authors:[{id:"161657",title:"Dr.",name:"Filippo",middleName:null,surname:"De Carlo",slug:"filippo-de-carlo",fullName:"Filippo De Carlo"},{id:"171361",title:"Dr.",name:"Maria Antonietta",middleName:null,surname:"Arleo",slug:"maria-antonietta-arleo",fullName:"Maria Antonietta Arleo"}]}],mostDownloadedChaptersLast30Days:[{id:"50094",title:"Reliability of Systems",slug:"reliability-of-systems",totalDownloads:3509,totalCrossrefCites:1,totalDimensionsCites:0,abstract:"Many objects consist of more components. The mutual arrangement of the individual elements influences the resultant reliability. The formulae are shown for the resultant reliability of series arrangement, as well as for parallel and combined arrangement. The possibility of reliability increasing by means of redundancy is explained, and also the principle of optimal allocation of reliabilities to individual elements. Everything is illustrated on examples.",book:{id:"5317",slug:"concise-reliability-for-engineers",title:"Concise Reliability for Engineers",fullTitle:"Concise Reliability for Engineers"},signatures:"Jaroslav Menčík",authors:[{id:"142710",title:"Prof.",name:"Jaroslav",middleName:null,surname:"Menčík",slug:"jaroslav-mencik",fullName:"Jaroslav Menčík"}]},{id:"50095",title:"Time to Failure of Deteriorating Objects",slug:"time-to-failure-of-deteriorating-objects",totalDownloads:1706,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"This chapter explains the prediction of the time to failure in the following cases: fatigue of metallic components under cyclic loading or in the presence of cracks, static fatigue, wear and creep, variable loading (damage accumulation). Prediction of the time to failure based on monitoring of the changing response. Probabilistic aspects of the lifetime prediction. The determination of the time to failure is illustrated on examples.",book:{id:"5317",slug:"concise-reliability-for-engineers",title:"Concise Reliability for Engineers",fullTitle:"Concise Reliability for Engineers"},signatures:"Jaroslav Menčík",authors:[{id:"142710",title:"Prof.",name:"Jaroslav",middleName:null,surname:"Menčík",slug:"jaroslav-mencik",fullName:"Jaroslav Menčík"}]},{id:"66913",title:"Reliability Evaluation of Power Systems",slug:"reliability-evaluation-of-power-systems",totalDownloads:2044,totalCrossrefCites:3,totalDimensionsCites:7,abstract:"Reliability evaluation of electric power systems is an essential and vital issue in the planning, designing, and operation of power systems. An electric power system consists of a set of components interconnected with each other in some purposeful and meaningful manner. The object of a reliability evaluation is to derive suitable measures, criteria, and indices of reliable and dependable performance based on component outage data and configuration. For evaluating generated reliability, the components of interest are the generating units and system configuration, which refer to the specific unit(s) operated to serve the present or future load. The indices used to measure the generated reliability are probabilistic estimates of the ability of a particular generation configuration to supply the load demand. These indices are better understood as an assessment of system-wide generation adequacy and not as absolute measures of system reliability. The indices are sensitive to basic factors like unit size and unit availability and are most useful when comparing the relative reliability of different generation configurations. The system is deemed to operate successfully if there is enough generation capacity (adequate reserve) to satisfy the peak load (maximum demand). Firstly, generation model and load model are convolved (mutually combined) to yield the risk of supply shortages in the system. Secondly, probabilistic estimates of shortage risk are used as indices of bulk power system reliability evaluation for the considered configuration.",book:{id:"7687",slug:"reliability-and-maintenance-an-overview-of-cases",title:"Reliability and Maintenance",fullTitle:"Reliability and Maintenance - An Overview of Cases"},signatures:"Abdullah M. Al-Shaalan",authors:[{id:"274935",title:"Prof.",name:"Abdullah",middleName:"Mohammed",surname:"Al-Shaalan",slug:"abdullah-al-shaalan",fullName:"Abdullah Al-Shaalan"}]},{id:"58172",title:"X-Ray Techniques",slug:"x-ray-techniques",totalDownloads:2475,totalCrossrefCites:2,totalDimensionsCites:4,abstract:"This chapter reviewed existing X-ray techniques that can be used for the analysis of materials, inclusive of those used as engineering and structural components. These techniques are X-ray fluorescence (XRF) spectrometry, proton-induced X-ray emission (PIXE) spectrometry, and X-ray diffraction (XRD). These analytical techniques provide qualitative and quantitative information on the composition and structure of materials with precision. XRD gives information on the crystalline forms and amorphous content of materials, which could be quite useful in failure analysis if the type of failure brings about morphological changes in the material under investigation. PIXE and XRF provide information on the types of elements present in a sample material and their concentrations. PIXE is however preferable to XRF due to its higher sensitivity to trace elements and lower atomic number elements as well as its faster analysis. XRF and XRD are more commonly used than PIXE which is a powerful, high-tech method that is relatively new in the field of chemical research. In this chapter, the theory and principles of these analytical techniques are explained, and diagrams showing the components of spectrometers and diffractometers are provided with descriptions of how they function.",book:{id:"5720",slug:"failure-analysis-and-prevention",title:"Failure Analysis and Prevention",fullTitle:"Failure Analysis and Prevention"},signatures:"Clementina Dilim Igwebike-Ossi",authors:[{id:"219931",title:"Dr.",name:"Clementina",middleName:null,surname:"Igwebike-Ossi",slug:"clementina-igwebike-ossi",fullName:"Clementina Igwebike-Ossi"}]},{id:"57936",title:"Power System Reliability: Mathematical Models and Applications",slug:"power-system-reliability-mathematical-models-and-applications",totalDownloads:2822,totalCrossrefCites:5,totalDimensionsCites:10,abstract:"This chapter deals with power systems reliability including technical, economical, and decisional aspects. Knowing that almost 90% of failures occur in the distribution systems, great interest was dedicated to this part of the system, and the first work was oriented to reliability indices defined as objectives to attempt and as performance measures in the electricity market. Some works deal with the managers’ behavior, and the customers reactions are modeled using economic criteria in uncertain future and inspired from game theory. When studying components, degradation models were introduced and combined with the effects of socks to study the reliability changing during system operation. In some works, the correlation between maintenance policies and reliability aspects was highlighted. In a recent work, considering the importance of new technologies integration and renewable energy insertion to power systems, it was revealed that reliability aspects and energy sustainability are two fundamental issues of progress in a given society.",book:{id:"6024",slug:"system-reliability",title:"System Reliability",fullTitle:"System Reliability"},signatures:"Rabah Medjoudj, Hassiba Bediaf and Djamil Aissani",authors:[{id:"182165",title:"Dr.",name:"Rabah",middleName:null,surname:"Medjoudj",slug:"rabah-medjoudj",fullName:"Rabah Medjoudj"},{id:"182167",title:"Prof.",name:"Djamil",middleName:null,surname:"Aissani",slug:"djamil-aissani",fullName:"Djamil Aissani"},{id:"208149",title:"Ms.",name:"Hassiba",middleName:null,surname:"Bediaf",slug:"hassiba-bediaf",fullName:"Hassiba Bediaf"}]}],onlineFirstChaptersFilter:{topicId:"123",limit:6,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:90,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:107,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:33,numberOfPublishedChapters:330,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:14,numberOfPublishedChapters:145,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:9,numberOfPublishedChapters:140,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:123,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:112,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:22,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:11,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:"2753-6580",doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}},{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}}]},series:{item:{id:"6",title:"Infectious Diseases",doi:"10.5772/intechopen.71852",issn:"2631-6188",scope:"This series will provide a comprehensive overview of recent research trends in various Infectious Diseases (as per the most recent Baltimore classification). Topics will include general overviews of infections, immunopathology, diagnosis, treatment, epidemiology, etiology, and current clinical recommendations for managing infectious diseases. Ongoing issues, recent advances, and future diagnostic approaches and therapeutic strategies will also be discussed. This book series will focus on various aspects and properties of infectious diseases whose deep understanding is essential for safeguarding the human race from losing resources and economies due to pathogens.",coverUrl:"https://cdn.intechopen.com/series/covers/6.jpg",latestPublicationDate:"August 12th, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:13,editor:{id:"131400",title:"Prof.",name:"Alfonso J.",middleName:null,surname:"Rodriguez-Morales",slug:"alfonso-j.-rodriguez-morales",fullName:"Alfonso J. Rodriguez-Morales",profilePictureURL:"https://mts.intechopen.com/storage/users/131400/images/system/131400.png",biography:"Dr. Rodriguez-Morales is an expert in tropical and emerging diseases, particularly zoonotic and vector-borne diseases (especially arboviral diseases). He is the president of the Travel Medicine Committee of the Pan-American Infectious Diseases Association (API), as well as the president of the Colombian Association of Infectious Diseases (ACIN). He is a member of the Committee on Tropical Medicine, Zoonoses, and Travel Medicine of ACIN. He is a vice-president of the Latin American Society for Travel Medicine (SLAMVI) and a Member of the Council of the International Society for Infectious Diseases (ISID). Since 2014, he has been recognized as a Senior Researcher, at the Ministry of Science of Colombia. He is a professor at the Faculty of Medicine of the Fundacion Universitaria Autonoma de las Americas, in Pereira, Risaralda, Colombia. He is an External Professor, Master in Research on Tropical Medicine and International Health, Universitat de Barcelona, Spain. He is also a professor at the Master in Clinical Epidemiology and Biostatistics, Universidad Científica del Sur, Lima, Peru. In 2021 he has been awarded the “Raul Isturiz Award” Medal of the API. Also, in 2021, he was awarded with the “Jose Felix Patiño” Asclepius Staff Medal of the Colombian Medical College, due to his scientific contributions to COVID-19 during the pandemic. He is currently the Editor in Chief of the journal Travel Medicine and Infectious Diseases. His Scopus H index is 47 (Google Scholar H index, 68).",institutionString:"Institución Universitaria Visión de las Américas, Colombia",institution:null},editorTwo:null,editorThree:null},subseries:{paginationCount:4,paginationItems:[{id:"3",title:"Bacterial Infectious Diseases",coverUrl:"https://cdn.intechopen.com/series_topics/covers/3.jpg",isOpenForSubmission:!0,editor:{id:"205604",title:"Dr.",name:"Tomas",middleName:null,surname:"Jarzembowski",slug:"tomas-jarzembowski",fullName:"Tomas Jarzembowski",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRKriQAG/Profile_Picture_2022-06-16T11:01:31.jpg",biography:"Tomasz Jarzembowski was born in 1968 in Gdansk, Poland. He obtained his Ph.D. degree in 2000 from the Medical University of Gdańsk (UG). After specialization in clinical microbiology in 2003, he started studying biofilm formation and antibiotic resistance at the single-cell level. In 2015, he obtained his D.Sc. degree. His later study in cooperation with experts in nephrology and immunology resulted in the designation of the new diagnostic method of UTI, patented in 2017. He is currently working at the Department of Microbiology, Medical University of Gdańsk (GUMed), Poland. Since many years, he is a member of steering committee of Gdańsk branch of Polish Society of Microbiologists, a member of ESCMID. He is also a reviewer and a member of editorial boards of a number of international journals.",institutionString:"Medical University of Gdańsk, Poland",institution:null},editorTwo:{id:"484980",title:"Dr.",name:"Katarzyna",middleName:null,surname:"Garbacz",slug:"katarzyna-garbacz",fullName:"Katarzyna Garbacz",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003St8TAQAZ/Profile_Picture_2022-07-07T09:45:16.jpg",biography:"Katarzyna Maria Garbacz, MD, is an Associate Professor at the Medical University of Gdańsk, Poland and she is head of the Department of Oral Microbiology of the Medical University of Gdańsk. She has published more than 50 scientific publications in peer-reviewed journals. She has been a project leader funded by the National Science Centre of Poland. Prof. Garbacz is a microbiologist working on applied and fundamental questions in microbial epidemiology and pathogenesis. Her research interest is in antibiotic resistance, host-pathogen interaction, and therapeutics development for staphylococcal pathogens, mainly Staphylococcus aureus, which causes hospital-acquired infections. Currently, her research is mostly focused on the study of oral pathogens, particularly Staphylococcus spp.",institutionString:"Medical University of Gdańsk, Poland",institution:null},editorThree:null},{id:"4",title:"Fungal Infectious Diseases",coverUrl:"https://cdn.intechopen.com/series_topics/covers/4.jpg",isOpenForSubmission:!0,editor:{id:"174134",title:"Dr.",name:"Yuping",middleName:null,surname:"Ran",slug:"yuping-ran",fullName:"Yuping Ran",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bS9d6QAC/Profile_Picture_1630330675373",biography:"Dr. Yuping Ran, Professor, Department of Dermatology, West China Hospital, Sichuan University, Chengdu, China. Completed the Course Medical Mycology, the Centraalbureau voor Schimmelcultures (CBS), Fungal Biodiversity Centre, Netherlands (2006). International Union of Microbiological Societies (IUMS) Fellow, and International Emerging Infectious Diseases (IEID) Fellow, Centers for Diseases Control and Prevention (CDC), Atlanta, USA. Diploma of Dermatological Scientist, Japanese Society for Investigative Dermatology. Ph.D. of Juntendo University, Japan. Bachelor’s and Master’s degree, Medicine, West China University of Medical Sciences. Chair of Sichuan Medical Association Dermatology Committee. General Secretary of The 19th Annual Meeting of Chinese Society of Dermatology and the Asia Pacific Society for Medical Mycology (2013). In charge of the Annual Medical Mycology Course over 20-years authorized by National Continue Medical Education Committee of China. Member of the board of directors of the Asia-Pacific Society for Medical Mycology (APSMM). Associate editor of Mycopathologia. Vice-chief of the editorial board of Chinses Journal of Mycology, China. Board Member and Chair of Mycology Group of Chinese Society of Dermatology.",institutionString:null,institution:{name:"Sichuan University",institutionURL:null,country:{name:"China"}}},editorTwo:null,editorThree:null},{id:"5",title:"Parasitic Infectious Diseases",coverUrl:"https://cdn.intechopen.com/series_topics/covers/5.jpg",isOpenForSubmission:!0,editor:{id:"67907",title:"Dr.",name:"Amidou",middleName:null,surname:"Samie",slug:"amidou-samie",fullName:"Amidou Samie",profilePictureURL:"https://mts.intechopen.com/storage/users/67907/images/system/67907.jpg",biography:"Dr. Amidou Samie is an Associate Professor of Microbiology at the University of Venda, in South Africa, where he graduated for his PhD in May 2008. He joined the Department of Microbiology the same year and has been giving lectures on topics covering parasitology, immunology, molecular biology and industrial microbiology. He is currently a rated researcher by the National Research Foundation of South Africa at category C2. He has published widely in the field of infectious diseases and has overseen several MSc’s and PhDs. His research activities mostly cover topics on infectious diseases from epidemiology to control. His particular interest lies in the study of intestinal protozoan parasites and opportunistic infections among HIV patients as well as the potential impact of childhood diarrhoea on growth and child development. He also conducts research on water-borne diseases and water quality and is involved in the evaluation of point-of-use water treatment technologies using silver and copper nanoparticles in collaboration with the University of Virginia, USA. He also studies the use of medicinal plants for the control of infectious diseases as well as antimicrobial drug resistance.",institutionString:null,institution:{name:"University of Venda",institutionURL:null,country:{name:"South Africa"}}},editorTwo:null,editorThree:null},{id:"6",title:"Viral Infectious Diseases",coverUrl:"https://cdn.intechopen.com/series_topics/covers/6.jpg",isOpenForSubmission:!0,editor:{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",biography:"Professor Dr. Shailendra K. Saxena is a vice dean and professor at King George's Medical University, Lucknow, India. His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research work has been published in various high-impact factor journals (Science, PNAS, Nature Medicine) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. Dr. Saxena is a fellow of various international societies/academies including the Royal College of Pathologists, United Kingdom; Royal Society of Medicine, London; Royal Society of Biology, United Kingdom; Royal Society of Chemistry, London; and Academy of Translational Medicine Professionals, Austria. He was named a Global Leader in Science by The Scientist. 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Saxena",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",institutionString:"King George's Medical University",institution:{name:"King George's Medical University",institutionURL:null,country:{name:"India"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},subseriesFiltersForPublishedBooks:[{group:"subseries",caption:"Bacterial Infectious Diseases",value:3,count:2},{group:"subseries",caption:"Parasitic Infectious Diseases",value:5,count:4},{group:"subseries",caption:"Viral Infectious Diseases",value:6,count:7}],publicationYearFilters:[{group:"publicationYear",caption:"2022",value:2022,count:2},{group:"publicationYear",caption:"2021",value:2021,count:4},{group:"publicationYear",caption:"2020",value:2020,count:3},{group:"publicationYear",caption:"2019",value:2019,count:3},{group:"publicationYear",caption:"2018",value:2018,count:1}],authors:{paginationCount:754,paginationItems:[{id:"310674",title:"Dr.",name:"Pravin",middleName:null,surname:"Kendrekar",slug:"pravin-kendrekar",fullName:"Pravin Kendrekar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/310674/images/system/310674.jpg",biography:"Dr. Pravin Kendrekar, MSc, MBA, Ph.D., is currently a visiting scientist at the Lipid Nanostructure Laboratory, University of Central Lancashire, England. He previously worked as a post-doctoral fellow at the Ben-Gurion University of Negev, Israel; University of the Free State, South Africa; and Central University of Technology Bloemfontein, South Africa. He obtained his Ph.D. in Organic Chemistry from Nagaoka University of Technology, Japan. He has published more than seventy-four journal articles and attended several national and international conferences as speaker and chair. Dr. Kendrekar has received many international awards. He has several funded projects, namely, anti-malaria drug development, MRSA, and SARS-CoV-2 activity of curcumin and its formulations. He has filed four patents in collaboration with the University of Central Lancashire and Mayo Clinic Infectious Diseases. His present research includes organic synthesis, drug discovery and development, biochemistry, nanoscience, and nanotechnology.",institutionString:"Visiting Scientist at Lipid Nanostructures Laboratory, Centre for Smart Materials, School of Natural Sciences, University of Central Lancashire",institution:null},{id:"428125",title:"Dr.",name:"Vinayak",middleName:null,surname:"Adimule",slug:"vinayak-adimule",fullName:"Vinayak Adimule",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/428125/images/system/428125.jpg",biography:"Dr. Vinayak Adimule, MSc, Ph.D., is a professor and dean of R&D, Angadi Institute of Technology and Management, India. He has 15 years of research experience as a senior research scientist and associate research scientist in R&D organizations. He has published more than fifty research articles as well as several book chapters. He has two Indian patents and two international patents to his credit. Dr. Adimule has attended, chaired, and presented papers at national and international conferences. He is a guest editor for Topics in Catalysis and other journals. He is also an editorial board member, life member, and associate member for many international societies and research institutions. His research interests include nanoelectronics, material chemistry, artificial intelligence, sensors and actuators, bio-nanomaterials, and medicinal chemistry.",institutionString:"Angadi Institute of Technology and Management",institution:null},{id:"284317",title:"Prof.",name:"Kantharaju",middleName:null,surname:"Kamanna",slug:"kantharaju-kamanna",fullName:"Kantharaju Kamanna",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/284317/images/21050_n.jpg",biography:"Prof. K. Kantharaju has received Bachelor of science (PCM), master of science (Organic Chemistry) and Doctor of Philosophy in Chemistry from Bangalore University. He worked as a Executive Research & Development @ Cadila Pharmaceuticals Ltd, Ahmedabad. He received DBT-postdoc fellow @ Molecular Biophysics Unit, Indian Institute of Science, Bangalore under the supervision of Prof. P. Balaram, later he moved to NIH-postdoc researcher at Drexel University College of Medicine, Philadelphia, USA, after his return from postdoc joined NITK-Surthakal as a Adhoc faculty at department of chemistry. Since from August 2013 working as a Associate Professor, and in 2016 promoted to Profeesor in the School of Basic Sciences: Department of Chemistry and having 20 years of teaching and research experiences.",institutionString:null,institution:{name:"Rani Channamma University, Belagavi",country:{name:"India"}}},{id:"158492",title:"Prof.",name:"Yusuf",middleName:null,surname:"Tutar",slug:"yusuf-tutar",fullName:"Yusuf Tutar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/158492/images/system/158492.jpeg",biography:"Prof. Dr. Yusuf Tutar conducts his research at the Hamidiye Faculty of Pharmacy, Department of Basic Pharmaceutical Sciences, Division of Biochemistry, University of Health Sciences, Turkey. He is also a faculty member in the Molecular Oncology Program. He obtained his MSc and Ph.D. at Oregon State University and Texas Tech University, respectively. He pursued his postdoctoral studies at Rutgers University Medical School and the National Institutes of Health (NIH/NIDDK), USA. His research focuses on biochemistry, biophysics, genetics, molecular biology, and molecular medicine with specialization in the fields of drug design, protein structure-function, protein folding, prions, microRNA, pseudogenes, molecular cancer, epigenetics, metabolites, proteomics, genomics, protein expression, and characterization by spectroscopic and calorimetric methods.",institutionString:"University of Health Sciences",institution:null},{id:"180528",title:"Dr.",name:"Hiroyuki",middleName:null,surname:"Kagechika",slug:"hiroyuki-kagechika",fullName:"Hiroyuki Kagechika",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/180528/images/system/180528.jpg",biography:"Hiroyuki Kagechika received his bachelor’s degree and Ph.D. in Pharmaceutical Sciences from the University of Tokyo, Japan, where he served as an associate professor until 2004. He is currently a professor at the Institute of Biomaterials and Bioengineering (IBB), Tokyo Medical and Dental University (TMDU). From 2010 to 2012, he was the dean of the Graduate School of Biomedical Science. Since 2012, he has served as the vice dean of the Graduate School of Medical and Dental Sciences. He has been the director of the IBB since 2020. Dr. Kagechika’s major research interests are the medicinal chemistry of retinoids, vitamins D/K, and nuclear receptors. He has developed various compounds including a drug for acute promyelocytic leukemia.",institutionString:"Tokyo Medical and Dental University",institution:{name:"Tokyo Medical and Dental University",country:{name:"Japan"}}},{id:"94311",title:"Prof.",name:"Martins",middleName:"Ochubiojo",surname:"Ochubiojo Emeje",slug:"martins-ochubiojo-emeje",fullName:"Martins Ochubiojo Emeje",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/94311/images/system/94311.jpeg",biography:"Martins Emeje obtained a BPharm with distinction from Ahmadu Bello University, Nigeria, and an MPharm and Ph.D. from the University of Nigeria (UNN), where he received the best Ph.D. award and was enlisted as UNN’s “Face of Research.” He established the first nanomedicine center in Nigeria and was the pioneer head of the intellectual property and technology transfer as well as the technology innovation and support center. Prof. Emeje’s several international fellowships include the prestigious Raman fellowship. He has published more than 150 articles and patents. He is also the head of R&D at NIPRD and holds a visiting professor position at Nnamdi Azikiwe University, Nigeria. He has a postgraduate certificate in Project Management from Walden University, Minnesota, as well as a professional teaching certificate and a World Bank certification in Public Procurement. Prof. Emeje was a national chairman of academic pharmacists in Nigeria and the 2021 winner of the May & Baker Nigeria Plc–sponsored prize for professional service in research and innovation.",institutionString:"National Institute for Pharmaceutical Research and Development",institution:{name:"National Institute for Pharmaceutical Research and Development",country:{name:"Nigeria"}}},{id:"436430",title:"Associate Prof.",name:"Mesut",middleName:null,surname:"Işık",slug:"mesut-isik",fullName:"Mesut Işık",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/436430/images/19686_n.jpg",biography:null,institutionString:null,institution:{name:"Bilecik University",country:{name:"Turkey"}}},{id:"268659",title:"Ms.",name:"Xianquan",middleName:null,surname:"Zhan",slug:"xianquan-zhan",fullName:"Xianquan Zhan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/268659/images/8143_n.jpg",biography:"Dr. Zhan received his undergraduate and graduate training in the fields of preventive medicine and epidemiology and statistics at the West China University of Medical Sciences in China during 1989 to 1999. He received his post-doctoral training in oncology and cancer proteomics for two years at the Cancer Research Institute of Human Medical University in China. In 2001, he went to the University of Tennessee Health Science Center (UTHSC) in USA, where he was a post-doctoral researcher and focused on mass spectrometry and cancer proteomics. Then, he was appointed as an Assistant Professor of Neurology, UTHSC in 2005. He moved to the Cleveland Clinic in USA as a Project Scientist/Staff in 2006 where he focused on the studies of eye disease proteomics and biomarkers. He returned to UTHSC as an Assistant Professor of Neurology in the end of 2007, engaging in proteomics and biomarker studies of lung diseases and brain tumors, and initiating the studies of predictive, preventive, and personalized medicine (PPPM) in cancer. In 2010, he was promoted to Associate Professor of Neurology, UTHSC. Currently, he is a Professor at Xiangya Hospital of Central South University in China, Fellow of Royal Society of Medicine (FRSM), the European EPMA National Representative in China, Regular Member of American Association for the Advancement of Science (AAAS), European Cooperation of Science and Technology (e-COST) grant evaluator, Associate Editors of BMC Genomics, BMC Medical Genomics, EPMA Journal, and Frontiers in Endocrinology, Executive Editor-in-Chief of Med One. He has\npublished 116 peer-reviewed research articles, 16 book chapters, 2 books, and 2 US patents. His current main research interest focuses on the studies of cancer proteomics and biomarkers, and the use of modern omics techniques and systems biology for PPPM in cancer, and on the development and use of 2DE-LC/MS for the large-scale study of human proteoforms.",institutionString:null,institution:{name:"Xiangya Hospital Central South University",country:{name:"China"}}},{id:"40482",title:null,name:"Rizwan",middleName:null,surname:"Ahmad",slug:"rizwan-ahmad",fullName:"Rizwan Ahmad",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/40482/images/system/40482.jpeg",biography:"Dr. Rizwan Ahmad is a University Professor and Coordinator, Quality and Development, College of Medicine, Imam Abdulrahman bin Faisal University, Saudi Arabia. Previously, he was Associate Professor of Human Function, Oman Medical College, Oman, and SBS University, Dehradun. Dr. Ahmad completed his education at Aligarh Muslim University, Aligarh. He has published several articles in peer-reviewed journals, chapters, and edited books. His area of specialization is free radical biochemistry and autoimmune diseases.",institutionString:"Imam Abdulrahman Bin Faisal University",institution:{name:"Imam Abdulrahman Bin Faisal University",country:{name:"Saudi Arabia"}}},{id:"41865",title:"Prof.",name:"Farid A.",middleName:null,surname:"Badria",slug:"farid-a.-badria",fullName:"Farid A. Badria",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/41865/images/system/41865.jpg",biography:"Farid A. Badria, Ph.D., is the recipient of several awards, including The World Academy of Sciences (TWAS) Prize for Public Understanding of Science; the World Intellectual Property Organization (WIPO) Gold Medal for best invention; Outstanding Arab Scholar, Kuwait; and the Khwarizmi International Award, Iran. He has 250 publications, 12 books, 20 patents, and several marketed pharmaceutical products to his credit. He continues to lead research projects on developing new therapies for liver, skin disorders, and cancer. Dr. Badria was listed among the world’s top 2% of scientists in medicinal and biomolecular chemistry in 2019 and 2020. He is a member of the Arab Development Fund, Kuwait; International Cell Research Organization–United Nations Educational, Scientific and Cultural Organization (ICRO–UNESCO), Chile; and UNESCO Biotechnology France",institutionString:"Mansoura University",institution:{name:"Mansoura University",country:{name:"Egypt"}}},{id:"329385",title:"Dr.",name:"Rajesh K.",middleName:"Kumar",surname:"Singh",slug:"rajesh-k.-singh",fullName:"Rajesh K. Singh",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/329385/images/system/329385.png",biography:"Dr. Singh received a BPharm (2003) and MPharm (2005) from Panjab University, Chandigarh, India, and a Ph.D. (2013) from Punjab Technical University (PTU), Jalandhar, India. He has more than sixteen years of teaching experience and has supervised numerous postgraduate and Ph.D. students. He has to his credit more than seventy papers in SCI- and SCOPUS-indexed journals, fifty-five conference proceedings, four books, six Best Paper Awards, and five projects from different government agencies. He is currently an editorial board member of eight international journals and a reviewer for more than fifty scientific journals. He received Top Reviewer and Excellent Peer Reviewer Awards from Publons in 2016 and 2017, respectively. He is also on the panel of The International Reviewer for reviewing research proposals for grants from the Royal Society. He also serves as a Publons Academy mentor and Bentham brand ambassador.",institutionString:"Punjab Technical University",institution:{name:"Punjab Technical University",country:{name:"India"}}},{id:"142388",title:"Dr.",name:"Thiago",middleName:"Gomes",surname:"Gomes Heck",slug:"thiago-gomes-heck",fullName:"Thiago Gomes Heck",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/142388/images/7259_n.jpg",biography:null,institutionString:null,institution:{name:"Universidade Regional do Noroeste do Estado do Rio Grande do Sul",country:{name:"Brazil"}}},{id:"336273",title:"Assistant Prof.",name:"Janja",middleName:null,surname:"Zupan",slug:"janja-zupan",fullName:"Janja Zupan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/336273/images/14853_n.jpeg",biography:"Janja Zupan graduated in 2005 at the Department of Clinical Biochemistry (superviser prof. dr. Janja Marc) in the field of genetics of osteoporosis. Since November 2009 she is working as a Teaching Assistant at the Faculty of Pharmacy, Department of Clinical Biochemistry. In 2011 she completed part of her research and PhD work at Institute of Genetics and Molecular Medicine, University of Edinburgh. She finished her PhD entitled The influence of the proinflammatory cytokines on the RANK/RANKL/OPG in bone tissue of osteoporotic and osteoarthritic patients in 2012. From 2014-2016 she worked at the Institute of Biomedical Sciences, University of Aberdeen as a postdoctoral research fellow on UK Arthritis research project where she gained knowledge in mesenchymal stem cells and regenerative medicine. She returned back to University of Ljubljana, Faculty of Pharmacy in 2016. She is currently leading project entitled Mesenchymal stem cells-the keepers of tissue endogenous regenerative capacity facing up to aging of the musculoskeletal system funded by Slovenian Research Agency.",institutionString:null,institution:{name:"University of Ljubljana",country:{name:"Slovenia"}}},{id:"357453",title:"Dr.",name:"Radheshyam",middleName:null,surname:"Maurya",slug:"radheshyam-maurya",fullName:"Radheshyam Maurya",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/357453/images/16535_n.jpg",biography:null,institutionString:null,institution:{name:"University of Hyderabad",country:{name:"India"}}},{id:"418340",title:"Dr.",name:"Jyotirmoi",middleName:null,surname:"Aich",slug:"jyotirmoi-aich",fullName:"Jyotirmoi Aich",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000038Ugi5QAC/Profile_Picture_2022-04-15T07:48:28.png",biography:"Biotechnologist with 15 years of research including 6 years of teaching experience. Demonstrated record of scientific achievements through consistent publication record (H index = 13, with 874 citations) in high impact journals such as Nature Communications, Oncotarget, Annals of Oncology, PNAS, and AJRCCM, etc. Strong research professional with a post-doctorate from ACTREC where I gained experimental oncology experience in clinical settings and a doctorate from IGIB where I gained expertise in asthma pathophysiology. A well-trained biotechnologist with diverse experience on the bench across different research themes ranging from asthma to cancer and other infectious diseases. An individual with a strong commitment and innovative mindset. Have the ability to work on diverse projects such as regenerative and molecular medicine with an overall mindset of improving healthcare.",institutionString:"DY Patil Deemed to Be University",institution:null},{id:"349288",title:"Prof.",name:"Soumya",middleName:null,surname:"Basu",slug:"soumya-basu",fullName:"Soumya Basu",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000035QxIDQA0/Profile_Picture_2022-04-15T07:47:01.jpg",biography:"Soumya Basu, Ph.D., is currently working as an Associate Professor at Dr. D. Y. Patil Biotechnology and Bioinformatics Institute, Dr. D. Y. Patil Vidyapeeth, Pune, Maharashtra, India. With 16+ years of trans-disciplinary research experience in Drug Design, development, and pre-clinical validation; 20+ research article publications in journals of repute, 9+ years of teaching experience, trained with cross-disciplinary education, Dr. Basu is a life-long learner and always thrives for new challenges.\r\nHer research area is the design and synthesis of small molecule partial agonists of PPAR-γ in lung cancer. She is also using artificial intelligence and deep learning methods to understand the exosomal miRNA’s role in cancer metastasis. Dr. Basu is the recipient of many awards including the Early Career Research Award from the Department of Science and Technology, Govt. of India. She is a reviewer of many journals like Molecular Biology Reports, Frontiers in Oncology, RSC Advances, PLOS ONE, Journal of Biomolecular Structure & Dynamics, Journal of Molecular Graphics and Modelling, etc. She has edited and authored/co-authored 21 journal papers, 3 book chapters, and 15 abstracts. She is a Board of Studies member at her university. She is a life member of 'The Cytometry Society”-in India and 'All India Cell Biology Society”- in India.",institutionString:"Dr. D.Y. Patil Vidyapeeth, Pune",institution:{name:"Dr. D.Y. Patil Vidyapeeth, Pune",country:{name:"India"}}},{id:"354817",title:"Dr.",name:"Anubhab",middleName:null,surname:"Mukherjee",slug:"anubhab-mukherjee",fullName:"Anubhab Mukherjee",position:null,profilePictureURL:"https://intech-files.s3.amazonaws.com/0033Y0000365PbRQAU/ProfilePicture%202022-04-15%2005%3A11%3A18.480",biography:"A former member of Laboratory of Nanomedicine, Brigham and Women’s Hospital, Harvard University, Boston, USA, Dr. Anubhab Mukherjee is an ardent votary of science who strives to make an impact in the lives of those afflicted with cancer and other chronic/acute ailments. He completed his Ph.D. from CSIR-Indian Institute of Chemical Technology, Hyderabad, India, having been skilled with RNAi, liposomal drug delivery, preclinical cell and animal studies. He pursued post-doctoral research at College of Pharmacy, Health Science Center, Texas A & M University and was involved in another postdoctoral research at Department of Translational Neurosciences and Neurotherapeutics, John Wayne Cancer Institute, Santa Monica, California. In 2015, he worked in Harvard-MIT Health Sciences & Technology as a visiting scientist. He has substantial experience in nanotechnology-based formulation development and successfully served various Indian organizations to develop pharmaceuticals and nutraceutical products. He is an inventor in many US patents and an author in many peer-reviewed articles, book chapters and books published in various media of international repute. Dr. Mukherjee is currently serving as Principal Scientist, R&D at Esperer Onco Nutrition (EON) Pvt. Ltd. and heads the Hyderabad R&D center of the organization.",institutionString:"Esperer Onco Nutrition Pvt Ltd.",institution:null},{id:"319365",title:"Assistant Prof.",name:"Manash K.",middleName:null,surname:"Paul",slug:"manash-k.-paul",fullName:"Manash K. Paul",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/319365/images/system/319365.png",biography:"Manash K. Paul is a Principal Investigator and Scientist at the University of California Los Angeles. He has contributed significantly to the fields of stem cell biology, regenerative medicine, and lung cancer. His research focuses on various signaling processes involved in maintaining stem cell homeostasis during the injury-repair process, deciphering lung stem cell niche, pulmonary disease modeling, immuno-oncology, and drug discovery. He is currently investigating the role of extracellular vesicles in premalignant lung cell migration and detecting the metastatic phenotype of lung cancer via machine-learning-based analyses of exosomal signatures. Dr. Paul has published in more than fifty peer-reviewed international journals and is highly cited. He is the recipient of many awards, including the UCLA Vice Chancellor’s award, a senior member of the Institute of Electrical and Electronics Engineers (IEEE), and an editorial board member for several international journals.",institutionString:"University of California Los Angeles",institution:{name:"University of California Los Angeles",country:{name:"United States of America"}}},{id:"311457",title:"Dr.",name:"Júlia",middleName:null,surname:"Scherer Santos",slug:"julia-scherer-santos",fullName:"Júlia Scherer Santos",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/311457/images/system/311457.jpg",biography:"Dr. Júlia Scherer Santos works in the areas of cosmetology, nanotechnology, pharmaceutical technology, beauty, and aesthetics. Dr. Santos also has experience as a professor of graduate courses. Graduated in Pharmacy, specialization in Cosmetology and Cosmeceuticals applied to aesthetics, specialization in Aesthetic and Cosmetic Health, and a doctorate in Pharmaceutical Nanotechnology. Teaching experience in Pharmacy and Aesthetics and Cosmetics courses. She works mainly on the following subjects: nanotechnology, cosmetology, pharmaceutical technology, aesthetics.",institutionString:"Universidade Federal de Juiz de Fora",institution:{name:"Universidade Federal de Juiz de Fora",country:{name:"Brazil"}}},{id:"219081",title:"Dr.",name:"Abdulsamed",middleName:null,surname:"Kükürt",slug:"abdulsamed-kukurt",fullName:"Abdulsamed Kükürt",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/219081/images/system/219081.png",biography:"Dr. Kükürt graduated from Uludağ University in Turkey. He started his academic career as a Research Assistant in the Department of Biochemistry at Kafkas University. In 2019, he completed his Ph.D. program in the Department of Biochemistry at the Institute of Health Sciences. He is currently working at the Department of Biochemistry, Kafkas University. He has 27 published research articles in academic journals, 11 book chapters, and 37 papers. He took part in 10 academic projects. He served as a reviewer for many articles. He still serves as a member of the review board in many academic journals. He is currently working on the protective activity of phenolic compounds in disorders associated with oxidative stress and inflammation.",institutionString:null,institution:{name:"Kafkas University",country:{name:"Turkey"}}},{id:"178366",title:"Dr.",name:"Volkan",middleName:null,surname:"Gelen",slug:"volkan-gelen",fullName:"Volkan Gelen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/178366/images/system/178366.jpg",biography:"Volkan Gelen is a Physiology specialist who received his veterinary degree from Kafkas University in 2011. Between 2011-2015, he worked as an assistant at Atatürk University, Faculty of Veterinary Medicine, Department of Physiology. In 2016, he joined Kafkas University, Faculty of Veterinary Medicine, Department of Physiology as an assistant professor. Dr. Gelen has been engaged in various academic activities at Kafkas University since 2016. There he completed 5 projects and has 3 ongoing projects. He has 60 articles published in scientific journals and 20 poster presentations in scientific congresses. His research interests include physiology, endocrine system, cancer, diabetes, cardiovascular system diseases, and isolated organ bath system studies.",institutionString:"Kafkas University",institution:{name:"Kafkas University",country:{name:"Turkey"}}},{id:"418963",title:"Dr.",name:"Augustine Ododo",middleName:"Augustine",surname:"Osagie",slug:"augustine-ododo-osagie",fullName:"Augustine Ododo Osagie",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/418963/images/16900_n.jpg",biography:"Born into the family of Osagie, a prince of the Benin Kingdom. I am currently an academic in the Department of Medical Biochemistry, University of Benin. Part of the duties are to teach undergraduate students and conduct academic research.",institutionString:null,institution:{name:"University of Benin",country:{name:"Nigeria"}}},{id:"192992",title:"Prof.",name:"Shagufta",middleName:null,surname:"Perveen",slug:"shagufta-perveen",fullName:"Shagufta Perveen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/192992/images/system/192992.png",biography:"Prof. Shagufta Perveen is a Distinguish Professor in the Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. Dr. Perveen has acted as the principal investigator of major research projects funded by the research unit of King Saud University. She has more than ninety original research papers in peer-reviewed journals of international repute to her credit. She is a fellow member of the Royal Society of Chemistry UK and the American Chemical Society of the United States.",institutionString:"King Saud University",institution:{name:"King Saud University",country:{name:"Saudi Arabia"}}},{id:"49848",title:"Dr.",name:"Wen-Long",middleName:null,surname:"Hu",slug:"wen-long-hu",fullName:"Wen-Long Hu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/49848/images/system/49848.jpg",biography:"Wen-Long Hu is Chief of the Division of Acupuncture, Department of Chinese Medicine at Kaohsiung Chang Gung Memorial Hospital, as well as an adjunct associate professor at Fooyin University and Kaohsiung Medical University. Wen-Long is President of Taiwan Traditional Chinese Medicine Medical Association. He has 28 years of experience in clinical practice in laser acupuncture therapy and 34 years in acupuncture. He is an invited speaker for lectures and workshops in laser acupuncture at many symposiums held by medical associations. He owns the patent for herbal preparation and producing, and for the supercritical fluid-treated needle. Dr. Hu has published three books, 12 book chapters, and more than 30 papers in reputed journals, besides serving as an editorial board member of repute.",institutionString:"Kaohsiung Chang Gung Memorial Hospital",institution:{name:"Kaohsiung Chang Gung Memorial Hospital",country:{name:"Taiwan"}}},{id:"298472",title:"Prof.",name:"Andrey V.",middleName:null,surname:"Grechko",slug:"andrey-v.-grechko",fullName:"Andrey V. Grechko",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/298472/images/system/298472.png",biography:"Andrey Vyacheslavovich Grechko, Ph.D., Professor, is a Corresponding Member of the Russian Academy of Sciences. He graduated from the Semashko Moscow Medical Institute (Semashko National Research Institute of Public Health) with a degree in Medicine (1998), the Clinical Department of Dermatovenerology (2000), and received a second higher education in Psychology (2009). Professor A.V. Grechko held the position of Сhief Physician of the Central Clinical Hospital in Moscow. He worked as a professor at the faculty and was engaged in scientific research at the Medical University. Starting in 2013, he has been the initiator of the creation of the Federal Scientific and Clinical Center for Intensive Care and Rehabilitology, Moscow, Russian Federation, where he also serves as Director since 2015. He has many years of experience in research and teaching in various fields of medicine, is an author/co-author of more than 200 scientific publications, 13 patents, 15 medical books/chapters, including Chapter in Book «Metabolomics», IntechOpen, 2020 «Metabolomic Discovery of Microbiota Dysfunction as the Cause of Pathology».",institutionString:"Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology",institution:null},{id:"199461",title:"Prof.",name:"Natalia V.",middleName:null,surname:"Beloborodova",slug:"natalia-v.-beloborodova",fullName:"Natalia V. Beloborodova",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/199461/images/system/199461.jpg",biography:'Natalia Vladimirovna Beloborodova was educated at the Pirogov Russian National Research Medical University, with a degree in pediatrics in 1980, a Ph.D. in 1987, and a specialization in Clinical Microbiology from First Moscow State Medical University in 2004. 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