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Prediction of Partition Coefficients and Permeability of Drug Molecules in Biological Systems with Abraham Model Solute Descriptors Derived from Measured Solubilities and Water-to-Organic Solvent Partition Coefficients

Written By

William E. Acree, Jr., Laura M. Grubbs and Michael H. Abraham

Submitted: 01 November 2010 Published: 10 February 2012

DOI: 10.5772/19082

From the Edited Volume

Toxicity and Drug Testing

Edited by William Acree

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Written By

William E. Acree, Jr., Laura M. Grubbs and Michael H. Abraham

Submitted: 01 November 2010 Published: 10 February 2012