Landslide classifications based on material and types of movements [13].
\\n\\n
IntechOpen was founded by scientists, for scientists, in order to make book publishing accessible around the globe. Over the last two decades, this has driven Open Access (OA) book publishing whilst levelling the playing field for global academics. Through our innovative publishing model and the support of the research community, we have now published over 5,700 Open Access books and are visited online by over three million academics every month. These researchers are increasingly working in broad technology-based subjects, driving multidisciplinary academic endeavours into human health, environment, and technology.
\\n\\nBy listening to our community, and in order to serve these rapidly growing areas which lie at the core of IntechOpen's expertise, we are launching a portfolio of Open Science journals:
\\n\\nAll three journals will publish under an Open Access model and embrace Open Science policies to help support the changing needs of academics in these fast-moving research areas. There will be direct links to preprint servers and data repositories, allowing full reproducibility and rapid dissemination of published papers to help accelerate the pace of research. Each journal has renowned Editors in Chief who will work alongside a global Editorial Board, delivering robust single-blind peer review. Supported by our internal editorial teams, this will ensure our authors will receive a quick, user-friendly, and personalised publishing experience.
\\n\\n"By launching our journals portfolio we are introducing new, dedicated homes for interdisciplinary technology-focused researchers to publish their work, whilst embracing Open Science and creating a unique global home for academics to disseminate their work. We are taking a leap toward Open Science continuing and expanding our fundamental commitment to openly sharing scientific research across the world, making it available for the benefit of all." Dr. Sara Uhac, IntechOpen CEO
\\n\\n"Our aim is to promote and create better science for a better world by increasing access to information and the latest scientific developments to all scientists, innovators, entrepreneurs and students and give them the opportunity to learn, observe and contribute to knowledge creation. Open Science promotes a swifter path from research to innovation to produce new products and services." Alex Lazinica, IntechOpen founder
\\n\\nIn conclusion, Natalia Reinic Babic, Head of Journal Publishing and Open Science at IntechOpen adds:
\\n\\n“On behalf of the journal team I’d like to thank all our Editors in Chief, Editorial Boards, internal supporting teams, and our scientific community for their continuous support in making this portfolio a reality - we couldn’t have done it without you! With your support in place, we are confident these journals will become as impactful and successful as our book publishing program and bring us closer to a more open (science) future.”
\\n\\nWe invite you to visit the journals homepage and learn more about the journal’s Editorial Boards, scope and vision as all three journals are now open for submissions.
\\n\\nFeel free to share this news on social media and help us mark this memorable moment!
\\n\\n\\n"}]',published:!0,mainMedia:{caption:"",originalUrl:"/media/original/237"}},components:[{type:"htmlEditorComponent",content:'
After years of being acknowledged as the world's leading publisher of Open Access books, today, we are proud to announce we’ve successfully launched a portfolio of Open Science journals covering rapidly expanding areas of interdisciplinary research.
\n\n\n\nIntechOpen was founded by scientists, for scientists, in order to make book publishing accessible around the globe. Over the last two decades, this has driven Open Access (OA) book publishing whilst levelling the playing field for global academics. Through our innovative publishing model and the support of the research community, we have now published over 5,700 Open Access books and are visited online by over three million academics every month. These researchers are increasingly working in broad technology-based subjects, driving multidisciplinary academic endeavours into human health, environment, and technology.
\n\nBy listening to our community, and in order to serve these rapidly growing areas which lie at the core of IntechOpen's expertise, we are launching a portfolio of Open Science journals:
\n\nAll three journals will publish under an Open Access model and embrace Open Science policies to help support the changing needs of academics in these fast-moving research areas. There will be direct links to preprint servers and data repositories, allowing full reproducibility and rapid dissemination of published papers to help accelerate the pace of research. Each journal has renowned Editors in Chief who will work alongside a global Editorial Board, delivering robust single-blind peer review. Supported by our internal editorial teams, this will ensure our authors will receive a quick, user-friendly, and personalised publishing experience.
\n\n"By launching our journals portfolio we are introducing new, dedicated homes for interdisciplinary technology-focused researchers to publish their work, whilst embracing Open Science and creating a unique global home for academics to disseminate their work. We are taking a leap toward Open Science continuing and expanding our fundamental commitment to openly sharing scientific research across the world, making it available for the benefit of all." Dr. Sara Uhac, IntechOpen CEO
\n\n"Our aim is to promote and create better science for a better world by increasing access to information and the latest scientific developments to all scientists, innovators, entrepreneurs and students and give them the opportunity to learn, observe and contribute to knowledge creation. Open Science promotes a swifter path from research to innovation to produce new products and services." Alex Lazinica, IntechOpen founder
\n\nIn conclusion, Natalia Reinic Babic, Head of Journal Publishing and Open Science at IntechOpen adds:
\n\n“On behalf of the journal team I’d like to thank all our Editors in Chief, Editorial Boards, internal supporting teams, and our scientific community for their continuous support in making this portfolio a reality - we couldn’t have done it without you! With your support in place, we are confident these journals will become as impactful and successful as our book publishing program and bring us closer to a more open (science) future.”
\n\nWe invite you to visit the journals homepage and learn more about the journal’s Editorial Boards, scope and vision as all three journals are now open for submissions.
\n\nFeel free to share this news on social media and help us mark this memorable moment!
\n\n\n'}],latestNews:[{slug:"intechopen-supports-asapbio-s-new-initiative-publish-your-reviews-20220729",title:"IntechOpen Supports ASAPbio’s New Initiative Publish Your Reviews"},{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"}]},book:{item:{type:"book",id:"6772",leadTitle:null,fullTitle:"Occupational Therapy - Therapeutic and Creative Use of Activity",title:"Occupational Therapy",subtitle:"Therapeutic and Creative Use of Activity",reviewType:"peer-reviewed",abstract:"Occupational therapy is a health care specialty with a deep focus on client-centered and holistic rehabilitation to improve the individual's occupational performance, quality of life and well-being through participation in meaningful and purposeful activities. This new book presents the importance of the therapeutic and creative use of activity in different populations, which is one of the core components of occupational therapy. Rehabilitation, rehabilitation delivery and outcomes are affected by recent changes in the meaning of health and social values. This resulted in an increasing necessity for therapeutic therapy, as well as creative use of activity in occupational therapy. This book focuses on recent advances in occupational therapy and reviews current practical guidelines. It introduces updated knowledge and skills for children, adults and the communities, including physical, mental, social, sensory, behavioral, environmental and community-based interventions to prevent, promote and improve activity use. The book will be relevant to occupational therapists, speech and language therapists, physical therapists, psychiatrists, psychologists, social workers and all the members of interdisciplinary rehabilitation team care workers.",isbn:"978-1-78984-411-5",printIsbn:"978-1-78984-410-8",pdfIsbn:"978-1-83881-701-5",doi:"10.5772/intechopen.72549",price:119,priceEur:129,priceUsd:155,slug:"occupational-therapy-therapeutic-and-creative-use-of-activity",numberOfPages:136,isOpenForSubmission:!1,isInWos:null,isInBkci:!1,hash:"0f6de90c02282919494d6254e473defe",bookSignature:"Meral Huri",publishedDate:"November 21st 2018",coverURL:"https://cdn.intechopen.com/books/images_new/6772.jpg",numberOfDownloads:11264,numberOfWosCitations:10,numberOfCrossrefCitations:7,numberOfCrossrefCitationsByBook:0,numberOfDimensionsCitations:10,numberOfDimensionsCitationsByBook:0,hasAltmetrics:1,numberOfTotalCitations:27,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"November 23rd 2017",dateEndSecondStepPublish:"December 14th 2017",dateEndThirdStepPublish:"February 12th 2018",dateEndFourthStepPublish:"May 3rd 2018",dateEndFifthStepPublish:"July 2nd 2018",currentStepOfPublishingProcess:5,indexedIn:"1,2,3,4,5,6",editedByType:"Edited by",kuFlag:!1,featuredMarkup:null,editors:[{id:"171525",title:"Dr.",name:"Meral",middleName:null,surname:"Huri",slug:"meral-huri",fullName:"Meral Huri",profilePictureURL:"https://mts.intechopen.com/storage/users/171525/images/5813_n.jpg",biography:"After graduation from the School of Physical Therapy in 2000, she received her MS and PhD degrees in Occupational Therapy from Hacettepe University, Turkey. Her research focuses on occupational science and the impact of occupational therapy on practitioners, children, and individuals with cancer. She is the author of 17 journal articles and 4 book chapters in occupational therapy and rehabilitation. She was awarded for her two studies in rehabilitation of patients with prostate cancer and interdisciplinary team approach in community health care. Dr. Huri is currently engaged in developing occupational therapy in Turkey and research collaboration with colleagues from all over the world.",institutionString:null,position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"2",totalChapterViews:"0",totalEditedBooks:"2",institution:{name:"Hacettepe University",institutionURL:null,country:{name:"Turkey"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"1126",title:"Occupational Therapy",slug:"physical-therapy-occupational-therapy"}],chapters:[{id:"62210",title:"Occupational Therapy’s Role in the Treatment of Children with Autism Spectrum Disorders",doi:"10.5772/intechopen.78696",slug:"occupational-therapy-s-role-in-the-treatment-of-children-with-autism-spectrum-disorders",totalDownloads:2762,totalCrossrefCites:1,totalDimensionsCites:0,hasAltmetrics:1,abstract:"Occupational therapists (OT) offer a wide range of therapies for individuals with ASD on the basis of specific deficits and difficulties. This chapter explores the role that OT plays, and the expertise, in relation to the interdisciplinary team. In addition, it discusses and presents empirical support for several therapeutic approaches commonly used by OTs working with individuals with ASD.",signatures:"Bryan M. Gee, Amy Nwora and Theodore W. Peterson",downloadPdfUrl:"/chapter/pdf-download/62210",previewPdfUrl:"/chapter/pdf-preview/62210",authors:[null],corrections:null},{id:"61806",title:"Executive Functions and Neurology in Children and Adolescents",doi:"10.5772/intechopen.78312",slug:"executive-functions-and-neurology-in-children-and-adolescents",totalDownloads:1767,totalCrossrefCites:3,totalDimensionsCites:5,hasAltmetrics:0,abstract:"This chapter discusses the theoretical and methodological issues of creating a developmental perspective on executive function (EF) in childhood and adolescence. Focusing on school periods, this section outlines the development of the basic components of EF—inhibition, working memory, and attention. Cognitive and neurophysiological evaluations show that despite the emergence of EF in the first few years of life, it continues to grow significantly in childhood and adolescence. The components vary slightly according to their developmental sequence. The chapter links findings to long-standing developmental issues (i.e. developmental sequences and processes) and suggests the necessary research to establish a developmental framework covering early childhood throughout adolescence.",signatures:"Gokcen Akyurek",downloadPdfUrl:"/chapter/pdf-download/61806",previewPdfUrl:"/chapter/pdf-preview/61806",authors:[{id:"197265",title:"Dr.",name:"Gokcen",surname:"Akyurek",slug:"gokcen-akyurek",fullName:"Gokcen Akyurek"}],corrections:null},{id:"62493",title:"Occupational Therapy in Forensic Settings",doi:"10.5772/intechopen.79366",slug:"occupational-therapy-in-forensic-settings",totalDownloads:2547,totalCrossrefCites:2,totalDimensionsCites:3,hasAltmetrics:0,abstract:"It is necessary for a person to comply with the expectations of society and the rules of law to which these expectations are secured. Offenders turn back to the community after the penalty was executed by isolating from society and some occupations. An occupational imbalance is seen in the individuals, during this penalty period and afterward, because of limited occupational participation. As an occupational being, this affects their physical, mental and psychological well-being. Imprisonment is an important practice in criminal law to punish criminals. This may be necessary for the protection of society from criminals, but successful integration into a community after exiting the prison is the most important factor in preventing recidivism. Occupational therapy focuses on health and well-being by using meaningful and purposeful occupations. Occupation involves any activity that people perform or participate in, such as giving care to themselves or others, working, learning, playing games, and interacting with others. From this perspective, the role of occupational therapists in forensic settings is to determine the abilities of these individuals to congregate their deprived freedoms and use them to train them for an independent and autonomous life; to provide a professional orientation, career counseling, and self-esteem; to gain some habits for physical, spiritual and moral life and to reinforce.",signatures:"Esma Ozkan, Sümeyye Belhan, Mahmut Yaran and Meral Zarif",downloadPdfUrl:"/chapter/pdf-download/62493",previewPdfUrl:"/chapter/pdf-preview/62493",authors:[null],corrections:null},{id:"61030",title:"Employment of People with Disabilities and Ergonomic Risk Factors at Workplace",doi:"10.5772/intechopen.76721",slug:"employment-of-people-with-disabilities-and-ergonomic-risk-factors-at-workplace",totalDownloads:1383,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:"The importance of employment to people with disabilities has been increasing in recent years. Participation in working life as active producers has been the main factor in community integration of people with disabilities. It has been proven that if people with disabilities are given the opportunity to develop and use their working capacity, they can be as successful as those who do not have any disabilities, and nowadays the most rational way of helping people with disabilities is to provide them with profession and work. Vocational rehabilitation is a process that helps someone to overcome the barriers when beginning to work, continuing to work, or returning to work after any accident, illness, or disorder. Although the employee is selected according to his/her ability according to the work to be done, it is very important that the place to work matches the physical and psychological characteristics of the employee. Ergonomics is important at working life as it affects productivity. Many different ergonomic risk factors are available to affect the quality of life of a person at workplace. This chapter focuses on the employment of people with disabilities, the risk factors they may face at workplace and assessment of risk factors.",signatures:"Beliz Belgen Kaygisiz",downloadPdfUrl:"/chapter/pdf-download/61030",previewPdfUrl:"/chapter/pdf-preview/61030",authors:[null],corrections:null},{id:"60928",title:"Animal-Assisted Therapy in Occupational Therapy",doi:"10.5772/intechopen.76468",slug:"animal-assisted-therapy-in-occupational-therapy",totalDownloads:1946,totalCrossrefCites:0,totalDimensionsCites:1,hasAltmetrics:0,abstract:"Developing technology, rehabilitation services, and health definitions have brought about the use of different treatments as well as traditional treatments. Some of these methods are virtual reality, animal-assisted practices, and aqua therapy. Animal-assisted approaches are the therapeutic methods of eliminating and using the problems that an individual experiences in the physical, emotional, psychological, social, sensory, and environmental development areas by taking advantage of human and animal interaction. These methods consist of two basic chapters: animal-assisted activities (AAAs) and animal-assisted therapies (AATs). An interdisciplinary team is needed to implement the methods. This team is composed of personnel, such as occupational therapist (OT), physiotherapist, speech therapist, special education specialist, and a psychologist, who have been trained in this area. In recent years, these methods have been used to increase social interaction with physical structure and functions in neurodevelopmental disorders such as autism spectrum disorder and cerebral palsy. In addition, it is actively used in mental disorders such as depression and anxiety because an improvement is observed by providing the individual to feel safe. When participation is considered in the context of independence in daily life activities are very important, the use of animal-assisted in occupational therapy.",signatures:"Sedef Şahin, Barkın Kose and Meral Zarif",downloadPdfUrl:"/chapter/pdf-download/60928",previewPdfUrl:"/chapter/pdf-preview/60928",authors:[{id:"183079",title:"Ph.D.",name:"Sedef",surname:"Şahin",slug:"sedef-sahin",fullName:"Sedef Şahin"},{id:"198859",title:"Dr.",name:"Meral",surname:"Zarif",slug:"meral-zarif",fullName:"Meral Zarif"},{id:"199029",title:"B.Sc.",name:"Barkın",surname:"Kose",slug:"barkin-kose",fullName:"Barkın Kose"}],corrections:null},{id:"62002",title:"New Flower Bed Design and Verification Supporting Horticultural Therapy Classes Based on Behavioral Observation",doi:"10.5772/intechopen.78311",slug:"new-flower-bed-design-and-verification-supporting-horticultural-therapy-classes-based-on-behavioral-",totalDownloads:860,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Horticultural therapy improves the elderly’s emotional and cognitive functions and also leads to their social participation and better overall health. We want to know about the problems of implementing horticultural therapy and how to improve it with the flower bed design. “House of Love” is a private nursing home in Taipei and had been the research base in this study. It was found that current horticultural classes heavily rely on teacher-centric and volunteer staff-assisted curricula, often not considering the specific physical and psychological needs the elderly usually face in classes. “Elderly Green” is a new design taking the requirements of horticultural classes in to consideration, providing for a maximum of flexibility under varying conditions by modulizing the flower bed. It allowed the elderly to do their gardening in a comfortable and less strenuous manner. “Elderly Green” is a centripetal flower bed design improved equally distributed care for each participant during class time and increased interaction among the elderly that reduces manpower needs.",signatures:"Meng-Cong Zheng",downloadPdfUrl:"/chapter/pdf-download/62002",previewPdfUrl:"/chapter/pdf-preview/62002",authors:[null],corrections:null}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},subseries:null,tags:null},relatedBooks:[{type:"book",id:"5711",title:"Occupational Therapy",subtitle:"Occupation Focused Holistic Practice in Rehabilitation",isOpenForSubmission:!1,hash:"38180e287b6cb09b8002b7ab485de2c2",slug:"occupational-therapy-occupation-focused-holistic-practice-in-rehabilitation",bookSignature:"Meral Huri",coverURL:"https://cdn.intechopen.com/books/images_new/5711.jpg",editedByType:"Edited by",editors:[{id:"171525",title:"Dr.",name:"Meral",surname:"Huri",slug:"meral-huri",fullName:"Meral Huri"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1591",title:"Infrared Spectroscopy",subtitle:"Materials Science, Engineering and Technology",isOpenForSubmission:!1,hash:"99b4b7b71a8caeb693ed762b40b017f4",slug:"infrared-spectroscopy-materials-science-engineering-and-technology",bookSignature:"Theophile Theophanides",coverURL:"https://cdn.intechopen.com/books/images_new/1591.jpg",editedByType:"Edited by",editors:[{id:"37194",title:"Dr.",name:"Theophile",surname:"Theophanides",slug:"theophile-theophanides",fullName:"Theophile Theophanides"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3161",title:"Frontiers in Guided Wave Optics and Optoelectronics",subtitle:null,isOpenForSubmission:!1,hash:"deb44e9c99f82bbce1083abea743146c",slug:"frontiers-in-guided-wave-optics-and-optoelectronics",bookSignature:"Bishnu Pal",coverURL:"https://cdn.intechopen.com/books/images_new/3161.jpg",editedByType:"Edited by",editors:[{id:"4782",title:"Prof.",name:"Bishnu",surname:"Pal",slug:"bishnu-pal",fullName:"Bishnu Pal"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"371",title:"Abiotic Stress in Plants",subtitle:"Mechanisms and Adaptations",isOpenForSubmission:!1,hash:"588466f487e307619849d72389178a74",slug:"abiotic-stress-in-plants-mechanisms-and-adaptations",bookSignature:"Arun Shanker and B. 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As a result, a geologist’s participation in landslide inventory, susceptibility, hazard, and risk mapping is critical. In landslide susceptibility, hazard, and risk mapping, mapping and analysis of previous and active landslide incidence are demanding tasks that can be used for landslide prevention and mitigation. Landslide disaster prevention and mitigation will not be effective unless the landslide-prone area is correctly mapped [1]. Landslides can bury animals and persons; demolish houses, farms, and infrastructures in a short amount of time [2] and Wubalem [3]. Hong et al. [2], Wubalem [4] are stated that within a short period, landslides can bury animals and humans, destroy houses, farms, and infrastructures. Landslide is one of the foremost destructive and dangerous natural hazards that cause numerous fatalities and economic losses worldwide [2, 5, 6, 7]. Therefore, landslide inventory, susceptibility, hazard, and risk mapping and assessment are vital to disaster loss reduction and function as a suggestion for sustainable land use planning.
The extenuation actions of landslide incidence within the planet are required determination of the causal factors, identification of prevailing landslides, and generation of landslide susceptibility, hazard, and risk map [8]. Landslide inventory mapping is extremely important to work out landslide type, failure mechanism, spatial distribution, and size in a given region. Landslide inventory is also important for landslide susceptibility, hazard, and risk mapping. Chen and Wang [9] explained that susceptibility, hazard, and risk maps of landslides are the results of the statistical relationship in between landslide governing factors and preexisting landslides. Susceptibility, hazard, and risk map of landslides are imperative for scientific support of the government’s response to land use practice and landslide hazards management [9, 10]. The landslide susceptibility or hazard mapping is not only to determine the factors that are most influential to the landslides that occurred within the region but also to appraisal the comparative influence of every landslide governing factors [9]. As stated by Chen and Wang [9], landslide susceptibility or hazard mapping is also significant to inaugurate an association between the factors and landslides to foresee the landslide hazard in the future. As a result, extensive and accurate landslide inventory mapping, as well as the creation of landslide susceptibility, hazard, and risk maps, is critical. Although the reason for landslide incidence and its mechanisms are so complex, human interventions, earthquakes, and heavy rainfall can trigger it. As Kifle [11]; Wubalem and Meten [4] stated that landslide incidence can also occur when the resistance force exceeds by driving force thanks to the destabilization of natural soil or rock slopes. This chapter is provided a summary of the sort of landslide type, factor, landslide inventory, landslide susceptibility, hazard, risk mapping, and validation approaches.
Landslide is that the movement of the mass of rock, debris, and earth downslope [12, 13, 14, 15]. Landslides are also defined as an outsized range of geotechnical phenomena under the influence of gravity. On another hand, a landslide is that the type of mass wasting activity that denotes any outward or downslope movement of soil and rock under the direct influence of gravity when the drive exceeds the resistance force of a slope [13, 14, 16]. These masses may range in size from card to entire mountainsides. Their movements may vary in velocities. Landslide as a geological hazard is caused by earthquake or eruption, rainfall, and act. This is often initiated when an area of a hill slope or sloping section of the seabed is rendered weak to support its weight. It is one of the foremost destructive natural hazards triggered by natural and man-made factors like an earthquake, rainfall [17], and act like an improper/poor quarry, and road construction/inadequate maintenance in mountainous terrain [18].
In geohazard mapping, susceptibility/vulnerability, hazard, and risk mapping are the foremost important activities to understand, mapping, and evaluating the spatiotemporal condition and level of risk because of geo-hazards. These terms have different meanings but some researchers use the terms interchangeably. Susceptibility refers to the probability of occurrence of an event within a selected type during a given location whereas hazard refers to the probability of occurrence of an event within a selected type and magnitude during a given location within a reference period. This means, susceptibility is usually used to predict the spatial occurrence of events, but the hazard is usually used to predict the spatiotemporal occurrence of events during a given terrain. The term risk refers to the expected losses or damage by events during a given region, which are the products of susceptibility, hazard, and elements in peril. Vulnerability means the degree of loss to a given element of the set of elements in peril resulting from the occurrence of natural phenomena of a given magnitude. It is expressed on a scale from 0 (no damage) to 1 (total damage). Elements at risk is potentially vulnerable of properties, population, and economic activities including public services in peril during a given area.
Landslides are usually classified based on the materials involved (rocks, debris, and soils) and on their mechanism and failure (Table 1). Other factors include groundwater content and the rate and dimension of the movement. Classifying and studying this phenomenon is important to manage damages because of the landslide. Classification of the landslide is the primary step to investigate landslides. According to Varnes [13, 19], landslides are classified based on the types of material, mode of movement, landslide activity, the rate of movement, depth, the magnitude of slide and moisture content.
Movement type | Slope material type | Source | |||
---|---|---|---|---|---|
Bedrock | Soil mass in failed slope | [13] | |||
Principal coarse | Principal fine | [13] | |||
Topples | Rock topple | Debris topple | Earth topple | [13] | |
Fall | Rock fall | Debris fall | Earth fall | [13] | |
Lateral spread | Rock spread | Debris spread | Earth spread | [13] | |
Slide | Translational slide | Rockslide | Debris slide | Earth slide | [13] |
Rotational slide | |||||
Flows | Rock flow (Deep creep) | Debris flow | Earth flow | [13] | |
Composite or complex Two or more principal types of movement in combination | [13] |
Landslide classifications based on material and types of movements [13].
Rotational landslides are more common in cohesive, homogeneous soils. The failure, which can be superficial or deep-rooted, occurs along curved surfaces concave upwards, having a shape of a spoon. Successive landslides occur mainly in stiff fissured clays with gradients similar to their angle of equilibrium and in soft very sensitive clays, where the initial landslide causes an accumulation of remolded clay, which as it flows, leaves the material higher up without support, so promoting successive failures. These failures are shallow but can have considerable lateral continuity [20]. Weak rock masses or those with a high degree of fracturing or weathering, where the structural discontinuities do not form preferred surfaces for failure may also suffer this type of successive landslides.
In translational slides, failure takes place along pre-existing planar surfaces or discontinuities (bedding planes, contact between different types of materials, structural surfaces, etc.) and sometimes the failure plane is a fine layer of clay material between more competent strata [20].
The sliding mass can be sometimes rectangular blocks that have been detached from the mass at discontinuities or tension cracks (block landslides). Translational slides generally move faster than rotational ones, because of their simple geometry of failure mechanism.
As defined by Vallejo and Ferrer [20], flows are mass movements of soil (mud or earth flows), debris (debris flows), or rock blocks (rock fragment flows) often with high water content, where the material behaves as a fluid undergoing continuous deformation but without having well-defined failure surfaces. Water is the main triggering factor because water decreases the strength of materials having low cohesion [20]. Flows mainly affect sensitive clay soils which show considerable loss of strength when mobilized; these movements are not very deep in their extent and develop on slopes <10°.
Mud or Earth flows occur in predominantly fine and homogeneous materials and may move at a speed of the many meters per second; the loss of strength is typically caused by water saturation. They are classified consistent with the sort of fabric, its strength, and its water content. Mudflows are generally small-scale and slow but sometimes especially in-saturated conditions, they are extensive and fast, with catastrophic consequences once they reach populated areas. Fine volcanic materials are particularly vulnerable to this sort of process.
Debris flows are complex movements, which include rock fragments, blocks, cobbles, and gravel in a fine-grained matrix of sands, silts, and clays. They occur on slopes covered with loose or non-consolidated material, especially where there is no vegetation cover.
Creep may be a very slow, almost imperceptible superficial movement (a few decimeters deep), which affects soils and weathered materials, causing continuous deformations that becomes progressively noticeable on slopes over time. This causes fences, walls, or posts to lean or offset and trees to be bent. Creep may be a time-dependent deformation and defines the deformational behavior of the fabric instead of the sort of movement.
Solifluction affects the saturated surface layer of slopes. This is often a slow movement produced by the freeze–thaw process because the daily or seasonal temperature variations change the water phase and water content of fine-grained soils in cold regions.
Rock falls are very quick free falls of rocks, which are dislodged from pre-existing discontinuity planes (tectonic, bedding surfaces, and tension cracks). The movement could also be by a vertical fall, by a series of bounces, or by rolling down the slope surface. They are common on steep slopes in mountainous areas, on cliffs, and generally, on rock walls and therefore the blocks are bounded by different sets of discontinuities often forming wedge-shaped blocks. The factors that cause rock falls include erosion and loss of support for previously loosened blocks in steep slopes, water pressures in discontinuities, and tension cracks and seismic shakes. Although the fallen blocks could also be relatively small in terms of volume, rock falls are sudden processes that pose a big risk to communication routes and buildings in mountainous zones and at the foot of steep slopes. Masses of soil can also fall from vertical natural and excavated slopes, thanks to the existence of tension cracks generated by tensional stresses or shrinkage cracks within the ground that has dried.
The toppling of strata or blocks of rock may be included in rock falls. Toppling occurs when the strata dip in the opposite direction to the slope and form naturally inclined blocks, which are free to rotate because of failure at the foot of the slope. Toppling tends to occur mainly on rocky slope faces, which intersect steeply dipping strata [20].
Rock avalanches are rapidly falling masses of rock and debris that detach themselves from steep slopes, sometimes amid ice or snow. The rock masses disintegrate during their fall and form deposits of very different block sizes and form deposits of very different block sizes, with no rounding from abrasion and chaotic distribution [20]. Rock avalanche deposits are unstructured and have great porosity [20]. Avalanches are generally the results of large-scale landslides or rock falls during which due to the steep gradient and therefore the lack of both structure and cohesion in their materials, travel down over steep slopes at great speed (up to 100 Km/h).
Debris avalanches are formed from rock material containing an excellent sort of sizes and should include large blocks and abundant fines [20]. Loose deposits and loose materials resulting from volcanic eruptions are susceptible to this process. The most difference with debris flows, aside from water content (which is not necessary for debris avalanches), is that the rate and speed of movement of the avalanche in areas of a steep gradient.
This sort of movement (also called lateral spreading) refers to the movement of rock blocks or coherent, cemented soil masses that rest on soft & deformable slopes. These movements are thanks to the loss of strength of the underlying material, which either flows or deformed under the load of the rigid blocks. Lateral spreading can also cause by liquefaction of the underlying material or by lateral extrusion of sentimental, wet clays under the load of the masses above them [20]. These movements occur on gentle slopes and should be very extensive.
Determining the states and distribution of landslides is extremely important to repair the consequences of landslides on infrastructures, lives, farmlands, and environments. The landslide are going to be found within the following different states of condition. Active landslide is currently moving. A suspended landslide has moved within the last twelve months but is not active at the present. A reactivated landslide is a lively landslide that has been inactive. An inactive landslide is a landslide, which did not moved at most for year.
Inactive landslides are often subdivided into these states:
A dormant landslide is an inactive landslide, which will be reactivated by its original causes or other causes.
An abandoned landslide is an inactive landslide that is not suffering from its original causes.
A stabilized landslide is an inactive landslide that has been shielded from its original causes by artificial remedial measures.
A relict landslide is an inactive landslide that developed under geomorphological or climate considerably different from those at the present.
Potential and existed landslides can be identified or recognized using different techniques considering various features that existed on the earth’s surface. Different features indicate landslide signs like
Depression at top (water ponding)
Bulging at toe Tension cracks
Water seepage (generally at toe)
Tilted and crooked trees
Change in vegetation
Change in topography
Change in drainage pattern
In hazard minimization, the evaluation of landslide conditioning and triggering factors is a very important task. Geodynamic processes affecting the earth’s surface cause mass movements of different types, sizes, and speeds [20]. Landslide movement is that the most frequent and widespread sort of mass movement generated by the gravitational downslope displacement of soil and rock masses [20]. The force of gravity and therefore the progressive weakening of geological materials, mainly thanks to weathering, alongside the action of other natural and environmental phenomena, make mass movements relatively common on the earth’s surface [20]. These processes create potential geological risks, as they will cause economic loss and social damage if they affect human activities, buildings, and infrastructure [20]. How to avoid these adverse effects is the subject of research including mass movements, their characteristics, instability mechanisms, controlling factors, and causes. To carry out this research, it is necessary to understand the characteristics and therefore the geological, geotechnical, and hydrogeological properties of the soil and rock materials involved and their mechanical behavior also because the factors that condition and trigger such movements [20]. Studies during this field should specialize in the investigation of [20]
Particular processes for the design of stabilizing measures to either mitigate or reduce damage.
Analysis of the factors, which control and trigger processes at particular locations, to stop possible movements.
Mapping either unstable or potentially unstable zones, in order that the hazardous areas are often delimited and preventive measures are often applied.
As usual, landslides might transpire when shear stress exceeds the shear strength of slope material. The factors that cause landslide have been classified as factors that contribute to an increase of the shear stress and factors that contribute to the decrease of shear strength; however, water is another factor contributing to both increasing and decreasing shear stress and shear strength of slope material respectively. Factors these increase shear stresses are included removal of lateral support; surcharge/ overloading, transitory earth stress, regional tilting, removal of underline support, and increase in lateral pressure. The factors that contribute to the decrease of shear strength of slope material include factors like initial state or inherent characteristics of materials and the changing or variable factors that tend to lower the shear strength of a material. On other hand, factors that control landslides are classified into two such as intrinsic/inherent/static and external/dynamic landslide factors [21, 22, 23].
According to Anbalangan [21], and Raghuvashi et al. [24], intrinsic parameters are the inherent controlling factors that outline the favorable or unfavorable condition within the slope. These include slope material, slope geometry, structural discontinuity, land use/cover, and groundwater. These factors have an excellent influence to decrease the strength of the slope material. Hence, mapping and perception of their impression are crucial for slope stability analysis.
The kind of fabric during a slope is closely associated with the sort of instability. Different lithology are going to be showed different degrees of susceptibility to potential slippage or failure. The stress–strain behavior of materials is governed by their strength properties, which also depend upon the presence of water. Sorts of failure and therefore the location of failure surfaces depend upon factors like alternating materials of various lithology, the extent of weathering, and therefore the presence of layers of sentimental material or hard strata. Soils, which are considered homogeneous materials, compared to rock masses, instability could also be generated by differences within the degree of compaction, cementation, and grain size, which can make sure areas more vulnerable to weakness and water flow. In rock masses, characterization and analysis of slope behavior are further complicated by the presence of layers of strata with differing strengths and properties [20].
Geological structures or discontinuities play a definitive role in conditioning the slope stability in rock masses. A mixture of structural elements and geometric slope parameters, like height, gradient, and orientation, defines problems, which will occur. The spatial distribution of discontinuities is that the structure of the rock mass [20]. The presence of those surfaces of weakness (bedding surfaces, joints, and faults) dipping towards the slope face implies the existence of potential failure planes on which sliding can readily occur.
The orientation and spatial distribution of discontinuities will condition the sort and mechanism of the instability. A specific system of fracturing will condition both the direction of movement and therefore the size of blocks susceptible to slide or the presence of a fault dipping towards a slope face will limit the unstable area. Structural changes and singularities within the rock mass, like Tectonized or shear areas, or abrupt changes within the dip of the strata, indicate heterogeneities from which failure might originate. Slope stability could also be suffering from changes to the initial conditions during excavation; for instance, the existence of tectonic in place stress related to compressive or extensional structures like folds and faults.
Most failures are caused by the effects of water in the ground, including pore pressures and erosion of the slope materials. Water is considered the worst enemy of slope stability, together with human actions where excavations are carried out without adequate geotechnical care. The presence of water in a slope reduces stability by decreasing ground strength and increasing forces, which favor instability. The main effects of water are a reduction in the shear strength of failure surfaces as effective normal stress, σ’n, decreases.
The following aspects should be known to understand the effects of water in a slope [20]: 1) Hydrogeological behavior of the materials 2) Presence of water table and piezo metric heads 3) Water flow in the slope 4) Relevant hydrogeological parameters: permeability coefficient or hydraulic conductivity, hydraulic gradient, transmissivity, and storage coefficient. One way of obtaining an approximate assessment of the entire force exerted by water on discontinuity surfaces or tension cracks is to assume the triangular distribution of hydrostatic pressure on these surfaces.
The possible failure of a slope along a surface depends on the strength, which depends on cohesion and therefore the interior angle of friction. The influence of geological history (e.g. consolidation, erosion, diagenetic processes, in situ stresses, and weathering) on the mechanical (shear strength) properties of soils must be determined considering the geological characteristics. In rock masses, mechanical behavior is decided by the strength properties of the discontinuities and therefore the intact rock counting on its degree of fracturing and the nature of the materials and discontinuities within it. The behavior of a tough rock mass generally depends on the characteristics of its discontinuities, although the lithology and its geological evolution can also play a crucial role. The shear strength of surfaces of weakness depends on their nature and origin, persistence, spacing, roughness, type and thickness of infill, and thus the presence of water.
Slope stability is highly control by in situ stresses [20]. The strain relief from decompression when the slope is excavated may transform its material properties [20]. In rock slopes, the weakest areas are often degraded and begin to behave like soft rock or granular soil. This effect is common in mudstone or mud-shale slopes subjected to high in place stresses; the rock formation is weakened into a granular material with cement-sized fragments several meters thick inside the slope, resulting in disintegration and collapse of the slope.
Slope morphometry refers to the steepness of the slope, which controls not only the strain distribution inside the slope mass but also affects weathering layer depth and surface runoff [25]. As reported by Lai [25], the degree and height of the slope influence the quantity of runoff and thus the extent of erosion. The steeper the slope, the upper velocity of water flowing down a slope and have higher erosive power. Thus, the slope material that supports the slope are getting to be removed and heighten the slope instability problem.
Aspect is that the orientation of the slope. Different slope direction has different weather, land cover, and radiation intensity that affects the exposure of the slope to radiation, wind impact, and rainfall [26, 27].
Curvature is that the measure of the roughness of a given terrain. The curvature may ask the concaveness, concaveness, and flatness of a slope. According to Pradhan [28, 29]; Alkhasawneh et al. [30], as cited in Meten et al. [26] the negative value refers to the valley, the positive value refers to Capitol Hill slope, and zero/ approaches zero value refers to flat acreage. The curvature condition controls the hydraulic condition and thus the consequences of gravity for slope stability.
External triggering factors are dynamic factors, which may trigger slope movement by increasing driving force. These triggering factors include rainfall, seismic and act. Static and dynamic loads exerted on slopes modify the force distribution and may produce instability. Static loads include the load of structures or buildings on a slope or loads derived from fills, waste dumps, or heavy vehicles, and when these loads are exerted on the slope head, they create a further weight, which will contribute to the destabilizing forces. Dynamic loads are mainly thanks to natural or induced seismicity and vibrations caused by nearby blasting. These mainly affect jointed rock masses by opening up pre-existing discontinuities, reducing their shear strength, and displacing rock blocks, which can then fall. Dynamic forces produced by an action earthquake can be given as a function of the maximum horizontal acceleration. Precipitation and climate regime influence slope stability by modifying groundwater content. The strength of the soil mass becomes loss due to changes in soil structure by alternating periods of rainfall and drought.
Man Made Factors: Abebe et al. [31]; Kifle [11, 32] is explained that the demand for new land for infrastructure, settlement, and agriculture are primary means in which humans can contribute to slope instability condition through the excavation of slope toe or slope faces, loading of slope crest, drawdown (or reservoirs), irrigation, mining, artificial vibration, deforestation, and water leakage from utilities.
Landslide inventory is that the simplest sort of landslide map [33]. The landslide inventory map portrays the spatial distribution, frequency, activity, size, time, type, displace material, the intensity of injury, and density of landslide. It is often used because the base for future landslide susceptibility, hazard, and risk prediction by evaluating the connection between the prevailing landslide event and landslide driving factors [34]. Besides, landslide inventory is often used to evaluate the accuracy and performance of the landslide susceptibility, hazard, and risk maps. Landslide inventory map shows the past and current landslide incidences, which may be prepared using various techniques like the aerial photograph, Google Earth imagery, field investigation, and evaluation of archive data including GIS tools. Depend upon the aim, the size of the base map or aerial photograph, the extent of the study area, and therefore the availability of resources, a landslide inventory map are often prepared using different techniques as expressed above [35]. For instance, a small-scale landslide inventory map (1,25,000) landslide inventory maps are often prepared for a selected area using aerial photographs at the size of >1:20,000, Google Earth Imagery analysis, and extensive fieldwork [3, 4, 36, 37]. The Google Earth Imagery may be a free tool that helps not only to spot statistic landslide boundary but also wont to determine the area coverage, perimeter, and distance of slope material movement compared to other techniques, however, it needs field for verification purpose. As a result, currently, from the active and old landslide scarps, researchers intended to spot historical landslides using statistic Google Earth Imagery analysis instead of an aerial photograph. Depend upon the dimensions of the landslide and therefore the mapping scale, active and old landslide boundaries are often digitized into polygons employing a GIS tool with the assistance of Google Earth Imagery, and eventually, a landslide inventory map are often produced. The landslide inventory is going to be classified as training data sets and testing landslide data sets (Figure 1). Most of the researchers classified landslides into 70% for training data sets and 30% for testing landslide data sets [26, 38, 39, 40]. As shown in Figures 2–4, Google Earth Imagery analysis is so effective for landslide inventory mapping. Landslide investigation is an important task in landslide disaster reduction strategies. It can be conducted to determine and predict old, active, and future landslide incidence by examining land features. For example, field survey is used to evaluate slope gradient, geomorphology, geology, drainage, nature of soil, land use land cover, surface and subsurface water, geodynamic process, old and active landslide conditions. Generally, the methods or techniques that used to investigate landslides are summarized in Table 2.
Landslide inventory map of the study area [
Landslide in Chemoga catchment, northwestern Ethiopia.
Landslide in Woldia area, northwestern Ethiopia.
Landslide in Dessie town, Ethiopia.
Scop | Phase of study | Methods or thechniques | Objectives |
---|---|---|---|
Regional landslide study | Preliminary | Review of existing information and existing maps. Google Earth Imagery analysis, Interpretation of aerial photos and remote sensing. | Identify processes and type of movements. Identify conditioning factors. General evaluation of stability of the area. Indentify location and boundary of landslide. |
General study | Field observations. Processes mapping. Factors mapping. | ||
Conducted to investigate landslides or slope failure for specific area | Study of process and causal factors | Field surveys. Preliminary underground investigation: geophysical methods. | Describe and classify processes and materials. Susceptibility analysis based on the existing processes and concurrence of conditioning factors. Record landslide type, location, magnitude, frequency, dimention, damage, and element at risk. |
Detail investigation | Boreholes, geophysical methods, in situ tests, sampling, Laboratory tests. | Describe and classify movements. Collect morphological, geological, hydrogeological and geomechanical data. | |
Monitoring | Inclinometers, extensometers, tiltometers, piezometers. | Collect data on speed, direction, stability analysis using Limit equilibrium methods and Stress–strain numerical models. Determine situation of failure planes, water pressures. | |
Stability analysis | Limit equilibrium methods. Stress–strain numerical models. | Define failure models and failure mechanisms. Evaluate stability. Design corrective measures. |
Summary of landslide investigation techniques [20].
Landslide susceptibility may be a quantitative or qualitative evaluation of landslide occurrence of a specific type in a given location that is wont to predict spatial distribution, classification, and area of existed or potentially prone area [12, 37]. However, a landslide hazard map is employed to predict future spatial and temporal landslide occurrence with a specific type and magnitude. Although both landslide susceptibility and hazard map are different concepts, many researchers are used the terms as interchangeable. The researchers consider their susceptibility map as a hazard map during which magnitude and frequency did not consider in their model generation. The landslide risk map is employed to predict the expected spatial and temporal losses or damage by landslide incidences during a given region, which are the products of susceptibility or vulnerability, hazard, and elements in danger. Although landslide susceptibility, hazard, and risk maps are the results of the connection between landslide events and sets of landslide factors supported expert judgment or statistical analysis, hazard and risk maps become differ by some input parameters. For instance, a landslide hazard map will have additional landslide frequency, and magnitude input parameters whereas for a risk map, both susceptibility and hazard map become input parameters besides, the element in danger. As stated by Wubalem [3], landslide susceptibility and hazard map results from the sum of all weighted landslide factors employing a raster calculator or weighted overlay method in ArcGIS. Compare to landslide susceptibility mapping, landslide hazard mapping required excellent landslide inventories that contain magnitude, date of occurrence, and frequency. The shortage of frequency, date of occurrence, and magnitude of landslide, landslide hazard mapping become a difficult task. Thus, landslide research trends are shifted to landslide susceptibility mapping for the last twenty century. Now a day, thanks to technological advancement, landslide hazard mapping becomes a simple task for that area frequently suffering from landslide incidence. Lithological, geomorphological, geological structure, hydrological, climatological, anthropological, seismic, and land use/cover parameters and detailed landslide inventories are the foremost important input variables in GIS-based landslide susceptibility mapping. However, landslide frequency and magnitude are additional parameters in landslide hazard mapping. The susceptibility, hazard, and risk map produced from the expert judgment have a subjective problem for weight rating of the consequences of sets of parameters; however, the statistical analysis helps to develop maps supported the statistical relationship between sets of parameters and past or current landslide inventory data. Detailed landslide susceptibility, hazard, and risk map are often also developed for selected purpose at large scales using physical-based approaches. During this case, geotechnical properties of soil or rock slope material, angle of slope, and pore water pressure are the foremost important parameters to get a landslide susceptibility map supported the extent of an element of safety. Then, the hazard map are often produced by considering the factor of safety, landslide frequency, and magnitude. The danger map also can produce on large scale. Finally, the accuracy of the small-scale and detailed models are often validated using landslide inventory data using different techniques.
Landslide susceptibility or hazard zonation is a technique used to classify the slope into zones based on the level of actual or potential landslide susceptibility and hazard. Landslide susceptibility and hazard zonation are important for a rapid assessment of slope stability over a large area [21]. Landslide susceptibility map can forecast/provide important information about the spatial future landslide occurrence [3]. However, a landslide hazard map can forecast the spatial and temporal future landslide occurrence. In landslide susceptibility and hazard mapping, several approaches are developed, which may be categorized into qualitative, semi-quantitative, and quantitative methods [41, 42, 43, 44, 45].
The expert evaluation method is a widely used technique, but a relatively subjective approach that explains the level of landslide condition in a descriptive expression based on the decision of the expert. Qualitative methods are an expert-driven approach, which required field experience specialists [41, 43, 45, 46, 47, 48, 49]. Field geomorphological analysis, landslide inventory analysis, and parameter assignment superimposition are the main activities for qualitative landslide susceptibility, and hazard mapping. Relying on the experience and professional background knowledge of experts and subjectivity is the drawback of these methods [41, 43, 45, 46, 47, 49]. This method has included heuristic, landslide inventory mapping, landslide hazard evaluation factor and slope stability evaluation parameter.
This method is opinion based that is used to classify landslide susceptibility and hazard maps by mapping all landslide factors, and landslide through proper rating each factor classes to prepare a landslide susceptibility and hazard map. The demerits of this method are its subjectivity.
Inventory is a simple method, which records the location and dimension of events occurred in the given area [50]. Landslide inventory is the way that used to record landslide location, size, occurrence time, displace material and types of slope failure. This method has used as the base for landslide susceptibility, hazard, and risk assessments; however, it does not provide the spatial relationship between landslide and sets of landslide factors rather than it only shows the location and volume of a landslide [51]. In this approach, landslide data can obtain through field mapping, historical record, satellite image or Google Earth Imagery analysis, and aerial photograph interpretation [36, 52].
According to Anbalagan [21] this method is used for landslide susceptibility and hazard zonation /mapping with consideration of the inherent controlling factors only. It is simple and cost-effective over a large area. Nevertheless, this method has the following limitations.
Has a rating of low value for groundwater effect on slope instability.
It does not account the triggering factors.
The condition of the rock mass with structural discontinuity and characteristics of the structural discontinuity (roughness, aperture, etc.) are not considered.
It is Subjective
Give the same rating for lithology and structural discontinuity but discontinuities have great influence than lithology.
Slope stability evaluation parameters (SSEP) is a landslide hazard zonation technique that is used to evaluate both inherent (slope material, slope geometry, structural discontinuity, land use and land cover, groundwater) and external factors (rainfall, seismicity, and human activity) to prepare landslide susceptibility map. Raghuvashi et al. [24], develop this method considering the dynamic and static landslide causative parameters. This technique is simple and supported by much field data but it is subjective for weighting assignment.
Semi-quantitative methods are the combination of qualitative and quantitative methods, which introduce grading and weighting of the effects of landslide factors on landslide incidence [42, 53, 54]. In this method, both qualitative and quantitative methods can be applied to evaluate the effects of landslide governing factors on landslide occurrence [55]. Analytical hierarchy process, weighted linear combination, and expert knowledge/heuristic [42, 48, 56, 57, 58, 59] are examples of semi-quantitative methods. Although some statistical concepts are introduced in this method, it depends on the expert’s experience and the background of professional knowledge and some subjectivity remains [42, 60].
According to Canoglu [61]; Chen et al. [62], the quantitative methods are grouped into three categories such as machine learning/data mining, physical-based, and statistical methods. The statistical methods are indirect methods which is extensively or routinely used to assess the association between landslide governing factors and landslides based on mathematical [9, 41]. They are classified into multivariate and bivariate statistical methods [3]. The statistical methods are provided reliable results [4, 26, 42, 63, 64, 65, 66, 67, 68, 69]. The numerical methods rely on the mathematical model, expression, and less expert judgments, which provides comparatively reliable results, unlike the qualitative method. Among quantitative methods, the statistical method is the one, which used to evaluate the spatial slope instability based on the relationship between the past/active landslide and landslide factors [70]. A statistical method is an indirect method used to prepare a landslide hazard/susceptibility map, which is considered as objective and worked by integrated GIS tool with statistical analysis based on the landslide and sets of landslide factors spatial relationship. However, in this method, the most difficult thing that we have to consider is accurate database construction, model calibration, and model validation iteration procedures [71]. In this method, each factor has mapped and overlaid over past/active landslides to carry out the contribution of each factor and subclass on the instability of the slope [24, 52, 72]. The limitation of the statistical method is its requirement for detailed and quality landslide and landslide factor data, and it is time-consuming to acquire them over a large area Raghuvashi et al. [24]. The statistical method cannot apply to the area where a landslide has not occurred. This is one of the limitations of statistical methods in landslide susceptibility, hazard, and risk mapping.
The bivariate statistical procedure is straightforward to use and update, which is capable to differentiate the consequences of every sub factor class for landslide occurrence. Within the bivariate statistical procedure, the presence of landslide has been considered because the variable and therefore the parameters that enhanced the occurrence of the landslide has been considered as the independent variable [73]. in this technique, each determinant map has been classified into sub-classes to work out the response of individual factor classes to landslide occurrence. The landslide factor classes are often combined with a landslide distribution map and weighting values supported the landslide densities of every determinant class. After weight value calculation, the weighted raster map is carefully sum up employing a raster calculator in Math algebra under the GIS tool to urge the landslide susceptibility index map. The landslide susceptibility or hazard index map are often reclassified using various methods like natural break under the GIS tool to urge the ultimate landslide susceptibility map. The benefits of bivariate statistical methods are they will cover an outsized area with effective cost; it is simple to apply; it can provide spatially distributed landslide information and its relationship with landslide factors. However, the bivariate statistical methods have the subsequent limitation 1. It cannot distinguish which factor is more influential and non-influential. 2. It cannot provides the knowledge about the inherent condition of the slope material like geotechnical method 3. It can predict the landslide susceptibility regions but it cannot be predicted when this landslide will occur and it needs landslide occurrence during a certain region to predict the opposite region which has some environmental factor. The load of evidence, information value, certainty factor, and frequency ratio is that the commonest techniques in bivariate statistical analysis.
This method will provide more realistic and accurate results. It also considers the mutual relationship among landslide factors, unlike bivariate statistical methods. The weight of causal factors indicates the relative contribution of every factor to the degree of hazard in a given land unit. The multivariate statistical procedure helps to perform multivariate statistical analysis unlike the bivariate statistical procedure. One among the merits of the multivariate method is capable to work out the influential power of individual landslide factors on landslide occurrence. Logistic regression, discriminant analysis, and cluster analysis are the foremost commonly applied techniques in this method.
In recent times, advanced data mining methods have been widely used in landslide susceptibility modeling., including random forest [56, 57, 58], boosted regression tree [74], classification and regression tree [74], Naïve Bayes [53, 75], support vector machines [32, 76], kernel LR [77], logistic model tree [56, 57, 58, 77], index of entropy [39], and artificial neural networks [56, 57, 58, 78, 79]. Data mining methods are incapable to work out the consequences of every landslide factor class, need high computing capacity, time-consuming, and therefore the internal calculation process of those methods is intensive and cannot easily be understood. Although both statistical and data mining methods have a bit little difference in the degree of predictive accuracy, they can provide reliable predictive accuracy landslide susceptibility map in landslide susceptibility or hazard mapping [78, 80].
The physical-based approach includes limit equilibrium and finite element numerical models. These methods can be applied for both soil and rock slope stability analysis. This method can provide hazard in absolute value /factor of safety or probability/quantitative results that can directly use for design purposes [52] and Raghuvashi et al. [24]. Physical-based methods are used to calculate the quantitative value of the inherent slope materials of the factor of safety over a defined area [81]. These methods can be applied when landslide types are simple (shallow landslides) and the intrinsic properties of slope material are homogeneous [81]. It requires detailed ground data such as unit weight of soil, soil strength, soil layer thickness, slope angle, pore water pressure, depth below the terrain surface, and slope height. The physical-based method has been employed over a small area, and oversimplification, data availability to acquire frequently is impossible are the drawback of these methods [81]. These methods can be focused on an on-site investigation to assess the geotechnical properties of soil/rock, soil depth, surface and subsurface water condition, the geometry of the slope, landslide location, failure mechanism, depth, and distance of landside. These methods are used to analyze slope conditions by calculating factors of safety using different software like PLAXIS and Slope/w in GeoStudio software package as two or three-dimensional models. The oversimplification of geological, geotechnical model and the difficulty to predict pore water pressure and its relationship with rainfall /snowmelt are the main problems that challenge use the of geotechnical approaches [82].
Landslide risk is the expected loss or damage due to landslide Incidences, which include fatalities, damage to properties, infrastructure, farmland, environment, interruption of services, and economic activities. As compare to landslide susceptibility, and hazard mapping, landslide risk mapping is not common so far due to it requires complex input parameters. It is a complex task due to the lack of necessary information to produce input parameters including vulnerability/susceptibility, hazard, and element at risk [33]. In addition to landslide susceptibility/vulnerability, and hazard maps, landslide risk map is very important in the regulation of land use, landslide risk management, and mitigation strategies. One has a plan to prepare a landslide risk map, it is necessary to estimate landslide susceptibility, hazard, and element at risk.
In landslide risk mapping, qualitative and quantitative techniques are commonly practiced methods. The qualitative (heuristic) method is used to estimate the level of risk in an area qualitatively, when the numerical estimation of hazard, vulnerability, and element at risk is difficult due to lack of landslide frequency, date of occurrence, and magnitude data [33, 83]. The landslide risk map can be produced based on the knowledge of experts about landslide vulnerability, hazard, and element at risk. In a quantitative approach, landslide risk can be estimated numerically using a mathematical equation developed by Varnes and IAEG Commission on landslides and other mass movements on slopes (1984). Risk = hazard*vulnerability*element at risk. Where the hazard is the probability of landslide occurrence in a particular type and magnitude in a given location within a referenced period. Vulnerability is the expected degree of loss due to landslides. Element at risk is potentially affected elements in landslide-affected areas.
In the case of model validation, landslide area has been classified based on time, space, and random partition [26, 84, 85]. The model can be validated by applied various validation techniques like predictive rate curve, success rate curve, simple overlay, a landslide percent comparison column chart, relative error, relative landslide density index (R – index), receiver operating characteristics (ROC), and landslide density.
As indicated in [26], the success rate curve can be plotted using training landslide against the landslide susceptibility or hazard or risk map area. Success rate and a predicted rate curve can be plotted using a cumulative percentage of training/testing landslide area against the cumulative percentage of the landslide susceptibility/hazard/risk map area [86]. For this purpose, the landslide susceptibility or hazard or risk index has to be reclassified into 100 classes by descending order of the value. Then landslide raster can be combined with these classes to obtain landslide pixels. Both landslide and map area pixels have converted into a cumulative percentage to plot the success and predicted rate curve. The success rate curve can be plotted using the cumulative percentage of training landslide vs. a cumulative percentage of map area while the predicted rate curve can be plotted using a cumulative percentage of testing or validation landslide area vs. map area. The success rate explains how well the model and how landslide susceptibility, hazard, and risk mapping results are classified the study area using training landslide data. The predict rate curve explains the predictive capability of the conditioning factor for the model. If the curve deflects and closes to the top left of the reference line along the diagonal, the model has higher accuracy.
As states by Pham et al., [87] and Fayez et al., [88], the landslide density has calculated using the equation of landslide density (LD). LD
Landslide susceptibility, hazard, and risk models can also be validated using the relative landslide density index, which is calculated using the following equation.
The other model validation technique relative error calculation is one of the techniques that help us to evaluate and determine the quality of the model and the number of landslides in the higher landslide susceptibility, hazard/risk classes. The higher the relative error value the poorer the model accuracy. When the relative error greater than 0.5, the model is not acceptable [90]. However when the relative error less than or equal to 0.5 and the number of landslide in the high landslide susceptibility/hazard/risk class more than half, the given model is accurate and reliable.
The ROC is the curve used to evaluate the performance of the landslide susceptibility, hazard, and risk models. ROC curve is the graphical representation of true positive rate (TPR) as y-axis and false positive rate (FPR) as x-axis. In the ROC curve, the area under the curve (AUC) is the most important diagnostic feature that helps to evaluate whether the model performance is accurate or not accurate. As stated by Yesilnacar and Topal [91], the value of AUC is usually found in between 0.5–1. The model has excellent performance when the AUC value is in between 0.9–1; the model has very good performance when the AUC value is in between 0.8–0.9. The model has good performance when the AUC value is between 0.7–0.8. When the value of AUC is between 0.6–0.7, the model has average performance however if the AUC value is between the range of 0.5–0.6 and equal to 0.5 or less than o.5, the model has poor and useless results.
Recent unconsolidated soil deposits, rugged topography, active gully, riverbank erosion, and improper land use practice characterize the study area (Uatzau), making it vulnerable to a variety of landslides, including earth fall, soil creep, weathered rockslide, soil slide, earth flow, and debris flow. Landslide susceptibility zones of the study area were determine using Frequency ratio (FR), certainty factor (CF), and information value (IV) models. These maps also depict the spatial distribution of projected landslides and the locations where they are expected to occur. The maps, on the other hand, may not be able to predict the amount of material that will be displaced, as well as the time and frequency with which the landslide will occur. The landslide susceptibility models can also helpful for preventative and mitigation measure of landslide hazard in regional land use planning [81, 82, 92, 93, 94, 95, 96]. The success rate curve and predictive rate curve were used to validate the maps using training and testing/validation landslide data sets. The success rate curve was used to assess how successfully the models identified the location and supported the landslide events that were occurring at the time [26, 96]. The prediction rate curve was created to assess how effectively the models can forecast future landslide events that are unknown [94, 96]. Within the region, steep slopes covered by very loose shallow soil deposits, closer to the stream, agricultural land on a steep slope, active gully erosion, and concave slope shapes resulted in the high and very high susceptibility classes, while the moderate susceptibility class is found in highland landscapes. Low plain landscapes and areas covered by vast weathering-resistant rock masses are into the realm of very low and low susceptibility of a region.
Zine et al. [97] stated that higher prediction accuracy (AUC = 89.05%) and AUC = 85.57%) was received using the information value and frequency ratio methods. Similarly, the frequency ratio approach outperformed the information value methods for both success rates (AUC = 83.27%) and prediction rate curve (AUC = 88.8%) in this investigation. The accuracy of the two models falls within the same ranges, which may be a good performance. The frequency ratio model revealed a slight difference in the AUC value. Qiqing et al. [40] stated that a high predictive accuracy of AUC value of 75 was received using a certainty factor model when compared to the prediction rate curve value (AUC = 64.08%) of information value model. However, their accuracy values were within the same ranges, suggesting that they performed well. Similarly, in the current model, the certainty factor model had a greater prediction rate value (AUC = 87.03%) than the information value model, which had a lower prediction rate value (AUC = 84.8%), but they both required an equivalent accuracy range, which may be a good performance. The work of Haoyuan et al. [98] supported the predictive rate value of the area under the receiver operating characteristic curve (AUC), showing that the frequency ratio and certainty factor models have the more or less similar predictive capacity, with the certainty factor model having 81.18% and the frequency ratio model having 80.14%, respectively. The Frequency ratio model, on the other hand, performed worse than the CF model. The two models in this study had essentially identical AUC values for the prediction rate curve (87.03% for the certainty factor model and 88.8% for the frequency ratio model) (Figure 5). The closer prediction capacity with AUC > 64% and AUC > 80%, respectively, fall within the range of good and extremely good performance, according to the three bivariate statistical methods in the literature and this work [91]. High and extremely high susceptibility classes encompassed nearly 20% of the research area in this study (Table 3). The landslide validation findings for the three models are more similar than they are dissimilar, and they are all in the same region of outstanding performance. Aside from that, the percentages of landslides that fall into the high and highly susceptible classes are nearly the same (60.4%, 65.5% & 68.1% for FR, CF, and IV, respectively). Because of these findings, the research effort concludes that in landslide susceptibility mapping, the three models have similar potential for identifying landslide-prone locations, although factor selection should take precedence over methodologies. However, when compared to the FR and CF approaches, the IV models’ moderate, high, and very high susceptibility area coverage exhibited minor differences in a single example. This is frequently due to flaws discovered in IV during weight rating for each factor class, i.e. when there is no landslide in a certain component class the IV results become zero. This gives a good indication of the model’s overall accuracy. FR and CF models are better for regional land use planning, landslide hazard mitigation, and prevention based on the prediction accuracy of AUC value. Although the generated maps cannot predict when and how often landslides will occur, they do show the spatial distribution of landslide risk.
Landslide susceptibility maps of frequency ratio (FR), certainty factor (CF), information value (IV) methods [
Information value method | LSI Value | LSI | Factor class area (%) | Validation data set (%) | Training data set (%) | AUC for validation landslide | AUC for training landslide |
---|---|---|---|---|---|---|---|
−0.5-0.9 | VLS | 15.5 | 3.9 | 6.3 | 0.848323 | 0.808265 | |
0.9–1.5 | LS | 24.3 | 7.9 | 11.8 | |||
1.5–2 | MS | 31.5 | 20.1 | 23.8 | |||
2.0–2.6 | HS | 21.1 | 40.8 | 31.8 | |||
2.6–4.1 | VHS | 7.6 | 27.3 | 26.3 | |||
−2.2- −0.97 | VLS | 17.8 | 4.7 | 6.0 | 0.870348 | 0.871933 | |
-0.97- −0.47 | LS | 31.0 | 12.3 | 16.4 | |||
-0.47-0.04 | MS | 28.8 | 17.5 | 24.8 | |||
0.04–0.74 | HS | 19.0 | 34.8 | 33.0 | |||
0.74–2.61 | VHS | 3.4 | 30.7 | 19.7 | |||
3.1–4.3 | VLS | 22.7 | 5.4 | 9.3 | 0.888337 | 0.832718 | |
4.3–4.8 | LS | 30.8 | 14.7 | 17.8 | |||
4.8–5.3 | MS | 22.4 | 19.5 | 20.0 | |||
5.3–6 | HS | 19.3 | 43.7 | 35.0 | |||
6–7.7 | VHS | 4.8 | 16.7 | 17.8 | |||
VLS is for very low susceptibility, LS stands for low susceptibility, MS stands for moderate susceptibility, HS stands for high susceptibility, VHS stands for very high susceptibility, LSI stands for landslide susceptibility index and AUC stands for area under the curve. |
Statistical summary of information value, certainty factor, and frequency ratio methods [36].
This chapter introduces and overview the concepts of landslide, type, factors, inventories, susceptibility, hazard, and risk. Moreover, different mapping and validation approaches were introduced. The confusing between the term susceptibility and hazard is clearly discussed. Detail and quality data should tend emphasis in getting quality landslide susceptibility, hazard, and risk maps. Field landslide investigation integrated with Google Earth Imagery analysis is vital to work out and record, the relative occurrence date, magnitude, dimension, type, and state of landslide. GIS-based landslide susceptibility, hazard, and risk mapping is suitable for regional scale where as physical based mapping is recommendable for detail landslide study where geotechnical investigation is require.
First and foremost, I want to express my gratitude to the almighty God for allowing me to complete this study project. Next, I would like to express my gratitude to my wonderful family and friends for their unwavering support during the research process. Finally, I would like to express my gratitude to the University of Gondar.
I was responsible for all aspects of the project, including the conception and design of the work, model development, statistical analysis, and interpretation of the results.
In this scenario, it is not appropriate.
Data and materials are readily available.
The corresponding author can provide all of the datasets that were utilized and analyzed during the current investigation.
There are no competing interests.
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More so, the mechanism by which heavy metals cause neurotoxicity, generate free radical which promotes oxidative stress damaging lipids, proteins and DNA molecules and how these free radicals propagate carcinogenesis are discussed. Alongside these mechanisms, the noxious health effects of these heavy metals are discussed.",book:{id:"7111",slug:"poisoning-in-the-modern-world-new-tricks-for-an-old-dog-",title:"Poisoning in the Modern World",fullTitle:"Poisoning in the Modern World - New Tricks for an Old Dog?"},signatures:"Godwill Azeh Engwa, Paschaline Udoka Ferdinand, Friday Nweke Nwalo and Marian N. Unachukwu",authors:[{id:"241837",title:"Mr.",name:"Godwill Azeh",middleName:null,surname:"Engwa",slug:"godwill-azeh-engwa",fullName:"Godwill Azeh Engwa"},{id:"274194",title:"BSc.",name:"Paschaline Ferdinand",middleName:null,surname:"Okeke",slug:"paschaline-ferdinand-okeke",fullName:"Paschaline Ferdinand Okeke"},{id:"286975",title:"Dr.",name:"Friday",middleName:null,surname:"Nweke Nwalo",slug:"friday-nweke-nwalo",fullName:"Friday Nweke Nwalo"},{id:"286976",title:"Dr.",name:"Marian",middleName:null,surname:"Unachukwu",slug:"marian-unachukwu",fullName:"Marian Unachukwu"}]},{id:"27687",doi:"10.5772/29869",title:"Heavy Metals and Human Health",slug:"heavy-metals-and-human-health",totalDownloads:18969,totalCrossrefCites:87,totalDimensionsCites:196,abstract:null,book:{id:"1012",slug:"environmental-health-emerging-issues-and-practice",title:"Environmental Health",fullTitle:"Environmental Health - Emerging Issues and Practice"},signatures:"Simone Morais, Fernando Garcia e Costa and Maria de Lourdes Pereira",authors:[{id:"13875",title:"Prof.",name:"Simone",middleName:null,surname:"Morais",slug:"simone-morais",fullName:"Simone Morais"},{id:"79715",title:"Prof.",name:"Maria De Lourdes",middleName:null,surname:"Pereira",slug:"maria-de-lourdes-pereira",fullName:"Maria De Lourdes Pereira"},{id:"87294",title:"Prof.",name:"Fernando",middleName:null,surname:"Garcia E Costa",slug:"fernando-garcia-e-costa",fullName:"Fernando Garcia E Costa"}]}],mostDownloadedChaptersLast30Days:[{id:"64851",title:"Herbal Medicines in African Traditional Medicine",slug:"herbal-medicines-in-african-traditional-medicine",totalDownloads:14590,totalCrossrefCites:33,totalDimensionsCites:58,abstract:"African traditional medicine is a form of holistic health care system organized into three levels of specialty, namely divination, spiritualism, and herbalism. The traditional healer provides health care services based on culture, religious background, knowledge, attitudes, and beliefs that are prevalent in his community. Illness is regarded as having both natural and supernatural causes and thus must be treated by both physical and spiritual means, using divination, incantations, animal sacrifice, exorcism, and herbs. Herbal medicine is the cornerstone of traditional medicine but may include minerals and animal parts. The adjustment is ok, but may be replaced with –‘ Herbal medicine was once termed primitive by western medicine but through scientific investigations there is a better understanding of its therapeutic activities such that many pharmaceuticals have been modeled on phytochemicals derived from it. Major obstacles to the use of African medicinal plants are their poor quality control and safety. Traditional medical practices are still shrouded with much secrecy, with few reports or documentations of adverse reactions. However, the future of African traditional medicine is bright if viewed in the context of service provision, increase of health care coverage, economic potential, and poverty reduction. Formal recognition and integration of traditional medicine into conventional medicine will hold much promise for the future.",book:{id:"6302",slug:"herbal-medicine",title:"Herbal Medicine",fullTitle:"Herbal Medicine"},signatures:"Ezekwesili-Ofili Josephine Ozioma and Okaka Antoinette Nwamaka\nChinwe",authors:[{id:"191264",title:"Prof.",name:"Josephine",middleName:"Ozioma",surname:"Ozioma Ezekwesili-Ofili",slug:"josephine-ozioma-ezekwesili-ofili",fullName:"Josephine Ozioma Ezekwesili-Ofili"},{id:"211585",title:"Prof.",name:"Antoinette",middleName:null,surname:"Okaka",slug:"antoinette-okaka",fullName:"Antoinette Okaka"}]},{id:"76640",title:"Control of Clinical Laboratory Errors by FMEA Model",slug:"control-of-clinical-laboratory-errors-by-fmea-model",totalDownloads:1214,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"Patient safety is an aim for clinical applications and is a fundamental principle of healthcare and quality management. The main global health organizations have incorporated patient safety in their review of work practices. The data provided by the medical laboratories have a direct impact on patient safety and a fault in any of processes such as strategic, operational and support, could affect it. To provide appreciate and reliable data to the physicians, it is important to emphasize the need to design risk management plan in the laboratory. Failure Mode and Effect Analysis (FMEA) is an efficient technique for error detection and reduction. Technical Committee of the International Organization for Standardization (ISO) licensed a technical specification for medical laboratories suggesting FMEA as a method for prospective risk analysis of high-risk processes. FMEA model helps to identify quality failures, their effects and risks with their reduction/elimination, which depends on severity, probability and detection. Applying FMEA in clinical approaches can lead to a significant reduction of the risk priority number (RPN).",book:{id:"9808",slug:"contemporary-topics-in-patient-safety-volume-1",title:"Contemporary Topics in Patient Safety",fullTitle:"Contemporary Topics in Patient Safety - Volume 1"},signatures:"Hoda Sabati, Amin Mohsenzadeh and Nooshin Khelghati",authors:[{id:"340486",title:"M.Sc.",name:"Hoda",middleName:null,surname:"Sabati",slug:"hoda-sabati",fullName:"Hoda Sabati"},{id:"348872",title:"M.Sc.",name:"Amin",middleName:null,surname:"Mohsenzadeh",slug:"amin-mohsenzadeh",fullName:"Amin Mohsenzadeh"},{id:"348874",title:"MSc.",name:"Nooshin",middleName:null,surname:"Khelghati",slug:"nooshin-khelghati",fullName:"Nooshin Khelghati"}]},{id:"64762",title:"Mechanism and Health Effects of Heavy Metal Toxicity in Humans",slug:"mechanism-and-health-effects-of-heavy-metal-toxicity-in-humans",totalDownloads:10470,totalCrossrefCites:107,totalDimensionsCites:247,abstract:"Several heavy metals are found naturally in the earth crust and are exploited for various industrial and economic purposes. Among these heavy metals, a few have direct or indirect impact on the human body. Some of these heavy metals such as copper, cobalt, iron, nickel, magnesium, molybdenum, chromium, selenium, manganese and zinc have functional roles which are essential for various diverse physiological and biochemical activities in the body. However, some of these heavy metals in high doses can be harmful to the body while others such as cadmium, mercury, lead, chromium, silver, and arsenic in minute quantities have delirious effects in the body causing acute and chronic toxicities in humans. The focus of this chapter is to describe the various mechanism of intoxication of some selected heavy metals in humans along with their health effects. Therefore it aims to highlight on biochemical mechanisms of heavy metal intoxication which involves binding to proteins and enzymes, altering their activity and causing damage. More so, the mechanism by which heavy metals cause neurotoxicity, generate free radical which promotes oxidative stress damaging lipids, proteins and DNA molecules and how these free radicals propagate carcinogenesis are discussed. Alongside these mechanisms, the noxious health effects of these heavy metals are discussed.",book:{id:"7111",slug:"poisoning-in-the-modern-world-new-tricks-for-an-old-dog-",title:"Poisoning in the Modern World",fullTitle:"Poisoning in the Modern World - New Tricks for an Old Dog?"},signatures:"Godwill Azeh Engwa, Paschaline Udoka Ferdinand, Friday Nweke Nwalo and Marian N. Unachukwu",authors:[{id:"241837",title:"Mr.",name:"Godwill Azeh",middleName:null,surname:"Engwa",slug:"godwill-azeh-engwa",fullName:"Godwill Azeh Engwa"},{id:"274194",title:"BSc.",name:"Paschaline Ferdinand",middleName:null,surname:"Okeke",slug:"paschaline-ferdinand-okeke",fullName:"Paschaline Ferdinand Okeke"},{id:"286975",title:"Dr.",name:"Friday",middleName:null,surname:"Nweke Nwalo",slug:"friday-nweke-nwalo",fullName:"Friday Nweke Nwalo"},{id:"286976",title:"Dr.",name:"Marian",middleName:null,surname:"Unachukwu",slug:"marian-unachukwu",fullName:"Marian Unachukwu"}]},{id:"65467",title:"Anesthesia Management for Large-Volume Liposuction",slug:"anesthesia-management-for-large-volume-liposuction",totalDownloads:6231,totalCrossrefCites:1,totalDimensionsCites:2,abstract:"The apparent easiness with which liposuction is performed favors that patients, young surgeons, and anesthesiologists without experience in this field ignore the many events that occur during this procedure. Liposuction is a procedure to improve the body contour and not a surgery to reduce weight, although recently people who have failed in their plans to lose weight look at liposuction as a means to contour their body figure. Tumescent liposuction of large volumes requires a meticulous selection of each patient; their preoperative evaluation and perioperative management are essential to obtain the expected results. The various techniques of general anesthesia are the most recommended and should be monitored in the usual way, as well as monitoring the total doses of infiltrated local anesthetics to avoid systemic toxicity. The management of intravenous fluids is controversial, but the current trend is the restricted use of hydrosaline solutions. The most feared complications are deep vein thrombosis, pulmonary thromboembolism, fat embolism, lung edema, hypothermia, infections and even death. The adherence to the management guidelines and prophylaxis of venous thrombosis/thromboembolism is mandatory.",book:{id:"6221",slug:"anesthesia-topics-for-plastic-and-reconstructive-surgery",title:"Anesthesia Topics for Plastic and Reconstructive Surgery",fullTitle:"Anesthesia Topics for Plastic and Reconstructive Surgery"},signatures:"Sergio Granados-Tinajero, Carlos Buenrostro-Vásquez, Cecilia\nCárdenas-Maytorena and Marcela Contreras-López",authors:[{id:"273532",title:"Dr.",name:"Sergio Octavio",middleName:null,surname:"Granados Tinajero",slug:"sergio-octavio-granados-tinajero",fullName:"Sergio Octavio Granados Tinajero"}]},{id:"30178",title:"Chest Mobilization Techniques for Improving Ventilation and Gas Exchange in Chronic Lung Disease",slug:"chest-mobilization-techniques-for-improving-ventilation-and-gas-exchange-in-chronic-lung-disease",totalDownloads:31230,totalCrossrefCites:1,totalDimensionsCites:6,abstract:null,book:{id:"648",slug:"chronic-obstructive-pulmonary-disease-current-concepts-and-practice",title:"Chronic Obstructive Pulmonary Disease",fullTitle:"Chronic Obstructive Pulmonary Disease - Current Concepts and Practice"},signatures:"Donrawee Leelarungrayub",authors:[{id:"73709",title:"Associate Prof.",name:"Jirakrit",middleName:null,surname:"Leelarungrayub",slug:"jirakrit-leelarungrayub",fullName:"Jirakrit Leelarungrayub"}]}],onlineFirstChaptersFilter:{topicId:"3",limit:6,offset:0},onlineFirstChaptersCollection:[{id:"83158",title:"Cannabis and the Brain: Friend or Foe?",slug:"cannabis-and-the-brain-friend-or-foe",totalDownloads:0,totalDimensionsCites:0,doi:"10.5772/intechopen.106669",abstract:"Legalization of cannabis in the US and other countries highlight the need to understand the health consequences of this substance use. Research indicates that some cannabis ingredients may play beneficial role in treating various medical conditions while other ingredients may pose health risks. This review is focused on the brain and mental health effects of cannabis use. The rationale for examining cannabis use in behavioral and neural conditions is that these conditions are highly widespread in the US and account for high level of medical healthcare and associated cost. The purpose of this review is to provide an overview of the known medicinal benefits of selected cannabis cannabinoids in conditions like pediatric epilepsy, attention deficit hyperactivity disorder, autism spectrum disorder, and the known side effects or contraindications in conditions such as addiction, cognition, and psychosis. Several recommendations are made as to studies that will help further understanding the increasing role of cannabis in neuropsychiatric health and disease.",book:{id:"11714",title:"Cannabinoids - Recent Perspectives and Applications in Human Health",coverURL:"https://cdn.intechopen.com/books/images_new/11714.jpg"},signatures:"Ali E. Dabiri and Ghassan S. Kassab"},{id:"83161",title:"Repurposing BCG and MMR Vaccines for Combating Covid-19: A Review and Opinion Based on Clinical Evidence",slug:"repurposing-bcg-and-mmr-vaccines-for-combating-covid-19-a-review-and-opinion-based-on-clinical-evide",totalDownloads:0,totalDimensionsCites:0,doi:"10.5772/intechopen.106788",abstract:"Our review comprehends past and recent developments encircling the two vaccines, BCG and MMR, which have efficacy lasting 10 years and are known to trigger the production of Interferon and various cytokines. BCG has depicted long-lasting effects, reduction in mortality, and hospitalizations associated with various diseases in different age groups as per studies across Sweden, West Africa, Spain, and Indonesia. Clinical trials are in progress in Holland, Australia, and Germany to study its effects on COVID-19. Most Asian countries with childhood BCG vaccination programs have shown lower COVID-19-related per capita death rates. The MMR vaccination has shown a reduction in hospitalizations and COVID-19-related deaths in about 11 countries, and a randomized clinical trial has been proposed in New Orleans. Reasons such as inhibition of pulmonary inflammation and structural similarity have been cited for such consequences. BCG and MMR may serve to shorten the duration of infection, minimize harmful pathology, reduce hospitalization rates, and curb the spread of the disease, but more research is required to assess the associated risks, especially for the elderly and people with comorbidities who are prone to severe complications of COVID-19.",book:{id:"11724",title:"COVID-19 Vaccines - Current State and Perspectives",coverURL:"https://cdn.intechopen.com/books/images_new/11724.jpg"},signatures:"Kasturi Mahesh Tawde, Aditya Manivannan Iyer and Harshal Ashok Pawar"},{id:"83136",title:"Vector Control: Insights Arising from the Post-Genomics Findings on Insects’ Reproductive Biology",slug:"vector-control-insights-arising-from-the-post-genomics-findings-on-insects-reproductive-biology",totalDownloads:1,totalDimensionsCites:0,doi:"10.5772/intechopen.106273",abstract:"The high prevalence of neglected vector-borne diseases, such as Chagas disease and dengue fever, imposes enormous health and financial burdens in developing countries. Historically, and still, to this day, the main effective methods to manage those diseases rely on vector population control. Although early efforts in understanding vector-specific biology resulted in important advancements in the development of strategies for the management of vector-borne diseases, studies regarding the complex physiology of local vector species were weakened by the expanding use of insecticide-based tools, which were, at the time, proven simpler and effective. The rising threat of insecticide resistance and climate change (which can expand endemic areas) has reemphasized the need to rely on thorough species-specific vector biology. One approach to controlling vector populations is to disrupt molecular processes or antagonize the metabolic targets required to produce viable eggs. Here, we discuss new findings arising from post-genomics molecular studies on vector reproductive biology and discuss their potential for the elaboration of new effective vector control interventions.",book:{id:"11227",title:"New Advances in Neglected Tropical Diseases",coverURL:"https://cdn.intechopen.com/books/images_new/11227.jpg"},signatures:"Isabela Ramos and Fabio Gomes"},{id:"83146",title:"Metabarcoding and Digital PCR (dPCR): Application in the Study of Neglected Tropical Diseases",slug:"metabarcoding-and-digital-pcr-dpcr-application-in-the-study-of-neglected-tropical-diseases",totalDownloads:3,totalDimensionsCites:0,doi:"10.5772/intechopen.106272",abstract:"neglected tropical diseases such as Chagas disease, dengue, Zika, chikungunya, and malaria cause millions of deaths each year and they are caused by a variety of pathogens whose diagnosis is very limited or subject to conventional testing, making a treatment less accessible, accurate and timely diagnosis for choosing their treatments. Traditional methods for pathogen detection have not been able to meet the growing need for diagnosis and control. The incorporation of new technologies such as next-generation sequencing (NGS) and digital PCR (dPCR) represent a better diagnostic possibility due to their ability to absolutely quantify pathogens with high selectivity and precision. Our planet is currently experiencing environmental changes of an unprecedented magnitude and rate, including climate change, globalized pollution, biodiversity loss, and land use changes, so neglected diseases require a comprehensive understanding of the ecology of vectors in the different eco-epidemiological contexts, as well as of the transmission cycles of pathogens and their transmission dynamics. In this sense, NGS and dPCR open a new panorama for a better understanding of these diseases with the aim of proposing new programs for their care.",book:{id:"11227",title:"New Advances in Neglected Tropical Diseases",coverURL:"https://cdn.intechopen.com/books/images_new/11227.jpg"},signatures:"María de la Soldedad Lagunes-Castro, Aracely López-Monteon, Daniel Guzmán-Gómez and Angel Ramos-Ligonio"},{id:"82798",title:"Biomarkers in Multiple Sclerosis",slug:"biomarkers-in-multiple-sclerosis",totalDownloads:1,totalDimensionsCites:0,doi:"10.5772/intechopen.106052",abstract:"Clinical, biological, and radiological evidence are currently needed to diagnose MS, but lack of preclinical biomarkers hinders the earliest possible diagnosis and treatment. Conventional biomarkers target immunity, blood-brain barrier disruption, demyelination, and neuronal and axonal damage, as well as mitochondrial activity. An increase of specific brain metabolites with 30–40% is registered before detection of MRI lesions in MS. Potential lipid biomarkers are fatty acids, phospholipids, and oxysterols. The role of proteoforms in the pathogenesis of MS was confirmed. Serum neurofilament light chains (sNfL) are currently being studied as a readily available biomarker for prognosis and response to treatment in MS. The sNfL levels reflect ongoing neuroaxonal damage caused by inflammation, and the sNfL levels predict disease activity over the next few years. The retinal nerve fiber layer (RNFL) thinning is reliable as a biomarker of disability worsening. The neutrophil-to-lymphocyte ratio and CRP are also MS biomarkers. The development of rationally targeted therapeutic agents that allow preventive treatment to stop the disease is also delayed without definite biomarkers.",book:{id:"11312",title:"Multiple Sclerosis - Genetics, Disease Mechanisms and Clinical Developments",coverURL:"https://cdn.intechopen.com/books/images_new/11312.jpg"},signatures:"Valentina Ignatova"},{id:"83129",title:"Airborne Transmission and Control of Influenza and Other Respiratory Pathogens",slug:"airborne-transmission-and-control-of-influenza-and-other-respiratory-pathogens",totalDownloads:1,totalDimensionsCites:0,doi:"10.5772/intechopen.106446",abstract:"Despite uncertainty about the specific transmission risk posed by airborne, spray-borne, and contact modes for influenza, SARS-CoV-2, and other respiratory viruses, there is evidence that airborne transmission via inhalation is important and often predominates. 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He has developed various compounds including a drug for acute promyelocytic leukemia.",institutionString:"Tokyo Medical and Dental University",institution:{name:"Tokyo Medical and Dental University",country:{name:"Japan"}}},{id:"94311",title:"Prof.",name:"Martins",middleName:"Ochubiojo",surname:"Ochubiojo Emeje",slug:"martins-ochubiojo-emeje",fullName:"Martins Ochubiojo Emeje",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/94311/images/system/94311.jpeg",biography:"Martins Emeje obtained a BPharm with distinction from Ahmadu Bello University, Nigeria, and an MPharm and Ph.D. from the University of Nigeria (UNN), where he received the best Ph.D. award and was enlisted as UNN’s “Face of Research.” He established the first nanomedicine center in Nigeria and was the pioneer head of the intellectual property and technology transfer as well as the technology innovation and support center. Prof. Emeje’s several international fellowships include the prestigious Raman fellowship. He has published more than 150 articles and patents. He is also the head of R&D at NIPRD and holds a visiting professor position at Nnamdi Azikiwe University, Nigeria. He has a postgraduate certificate in Project Management from Walden University, Minnesota, as well as a professional teaching certificate and a World Bank certification in Public Procurement. Prof. Emeje was a national chairman of academic pharmacists in Nigeria and the 2021 winner of the May & Baker Nigeria Plc–sponsored prize for professional service in research and innovation.",institutionString:"National Institute for Pharmaceutical Research and Development",institution:{name:"National Institute for Pharmaceutical Research and Development",country:{name:"Nigeria"}}},{id:"436430",title:"Associate Prof.",name:"Mesut",middleName:null,surname:"Işık",slug:"mesut-isik",fullName:"Mesut Işık",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/436430/images/19686_n.jpg",biography:null,institutionString:null,institution:{name:"Bilecik University",country:{name:"Turkey"}}},{id:"268659",title:"Ms.",name:"Xianquan",middleName:null,surname:"Zhan",slug:"xianquan-zhan",fullName:"Xianquan Zhan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/268659/images/8143_n.jpg",biography:"Dr. Zhan received his undergraduate and graduate training in the fields of preventive medicine and epidemiology and statistics at the West China University of Medical Sciences in China during 1989 to 1999. He received his post-doctoral training in oncology and cancer proteomics for two years at the Cancer Research Institute of Human Medical University in China. In 2001, he went to the University of Tennessee Health Science Center (UTHSC) in USA, where he was a post-doctoral researcher and focused on mass spectrometry and cancer proteomics. Then, he was appointed as an Assistant Professor of Neurology, UTHSC in 2005. He moved to the Cleveland Clinic in USA as a Project Scientist/Staff in 2006 where he focused on the studies of eye disease proteomics and biomarkers. He returned to UTHSC as an Assistant Professor of Neurology in the end of 2007, engaging in proteomics and biomarker studies of lung diseases and brain tumors, and initiating the studies of predictive, preventive, and personalized medicine (PPPM) in cancer. In 2010, he was promoted to Associate Professor of Neurology, UTHSC. Currently, he is a Professor at Xiangya Hospital of Central South University in China, Fellow of Royal Society of Medicine (FRSM), the European EPMA National Representative in China, Regular Member of American Association for the Advancement of Science (AAAS), European Cooperation of Science and Technology (e-COST) grant evaluator, Associate Editors of BMC Genomics, BMC Medical Genomics, EPMA Journal, and Frontiers in Endocrinology, Executive Editor-in-Chief of Med One. He has\npublished 116 peer-reviewed research articles, 16 book chapters, 2 books, and 2 US patents. His current main research interest focuses on the studies of cancer proteomics and biomarkers, and the use of modern omics techniques and systems biology for PPPM in cancer, and on the development and use of 2DE-LC/MS for the large-scale study of human proteoforms.",institutionString:null,institution:{name:"Xiangya Hospital Central South University",country:{name:"China"}}},{id:"40482",title:null,name:"Rizwan",middleName:null,surname:"Ahmad",slug:"rizwan-ahmad",fullName:"Rizwan Ahmad",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/40482/images/system/40482.jpeg",biography:"Dr. Rizwan Ahmad is a University Professor and Coordinator, Quality and Development, College of Medicine, Imam Abdulrahman bin Faisal University, Saudi Arabia. Previously, he was Associate Professor of Human Function, Oman Medical College, Oman, and SBS University, Dehradun. Dr. Ahmad completed his education at Aligarh Muslim University, Aligarh. He has published several articles in peer-reviewed journals, chapters, and edited books. His area of specialization is free radical biochemistry and autoimmune diseases.",institutionString:"Imam Abdulrahman Bin Faisal University",institution:{name:"Imam Abdulrahman Bin Faisal University",country:{name:"Saudi Arabia"}}},{id:"41865",title:"Prof.",name:"Farid A.",middleName:null,surname:"Badria",slug:"farid-a.-badria",fullName:"Farid A. Badria",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/41865/images/system/41865.jpg",biography:"Farid A. Badria, Ph.D., is the recipient of several awards, including The World Academy of Sciences (TWAS) Prize for Public Understanding of Science; the World Intellectual Property Organization (WIPO) Gold Medal for best invention; Outstanding Arab Scholar, Kuwait; and the Khwarizmi International Award, Iran. He has 250 publications, 12 books, 20 patents, and several marketed pharmaceutical products to his credit. He continues to lead research projects on developing new therapies for liver, skin disorders, and cancer. Dr. Badria was listed among the world’s top 2% of scientists in medicinal and biomolecular chemistry in 2019 and 2020. He is a member of the Arab Development Fund, Kuwait; International Cell Research Organization–United Nations Educational, Scientific and Cultural Organization (ICRO–UNESCO), Chile; and UNESCO Biotechnology France",institutionString:"Mansoura University",institution:{name:"Mansoura University",country:{name:"Egypt"}}},{id:"329385",title:"Dr.",name:"Rajesh K.",middleName:"Kumar",surname:"Singh",slug:"rajesh-k.-singh",fullName:"Rajesh K. Singh",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/329385/images/system/329385.png",biography:"Dr. Singh received a BPharm (2003) and MPharm (2005) from Panjab University, Chandigarh, India, and a Ph.D. (2013) from Punjab Technical University (PTU), Jalandhar, India. He has more than sixteen years of teaching experience and has supervised numerous postgraduate and Ph.D. students. He has to his credit more than seventy papers in SCI- and SCOPUS-indexed journals, fifty-five conference proceedings, four books, six Best Paper Awards, and five projects from different government agencies. He is currently an editorial board member of eight international journals and a reviewer for more than fifty scientific journals. He received Top Reviewer and Excellent Peer Reviewer Awards from Publons in 2016 and 2017, respectively. He is also on the panel of The International Reviewer for reviewing research proposals for grants from the Royal Society. He also serves as a Publons Academy mentor and Bentham brand ambassador.",institutionString:"Punjab Technical University",institution:{name:"Punjab Technical University",country:{name:"India"}}},{id:"142388",title:"Dr.",name:"Thiago",middleName:"Gomes",surname:"Gomes Heck",slug:"thiago-gomes-heck",fullName:"Thiago Gomes Heck",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/142388/images/7259_n.jpg",biography:null,institutionString:null,institution:{name:"Universidade Regional do Noroeste do Estado do Rio Grande do Sul",country:{name:"Brazil"}}},{id:"336273",title:"Assistant Prof.",name:"Janja",middleName:null,surname:"Zupan",slug:"janja-zupan",fullName:"Janja Zupan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/336273/images/14853_n.jpeg",biography:"Janja Zupan graduated in 2005 at the Department of Clinical Biochemistry (superviser prof. dr. Janja Marc) in the field of genetics of osteoporosis. Since November 2009 she is working as a Teaching Assistant at the Faculty of Pharmacy, Department of Clinical Biochemistry. In 2011 she completed part of her research and PhD work at Institute of Genetics and Molecular Medicine, University of Edinburgh. She finished her PhD entitled The influence of the proinflammatory cytokines on the RANK/RANKL/OPG in bone tissue of osteoporotic and osteoarthritic patients in 2012. From 2014-2016 she worked at the Institute of Biomedical Sciences, University of Aberdeen as a postdoctoral research fellow on UK Arthritis research project where she gained knowledge in mesenchymal stem cells and regenerative medicine. She returned back to University of Ljubljana, Faculty of Pharmacy in 2016. She is currently leading project entitled Mesenchymal stem cells-the keepers of tissue endogenous regenerative capacity facing up to aging of the musculoskeletal system funded by Slovenian Research Agency.",institutionString:null,institution:{name:"University of Ljubljana",country:{name:"Slovenia"}}},{id:"357453",title:"Dr.",name:"Radheshyam",middleName:null,surname:"Maurya",slug:"radheshyam-maurya",fullName:"Radheshyam Maurya",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/357453/images/16535_n.jpg",biography:null,institutionString:null,institution:{name:"University of Hyderabad",country:{name:"India"}}},{id:"418340",title:"Dr.",name:"Jyotirmoi",middleName:null,surname:"Aich",slug:"jyotirmoi-aich",fullName:"Jyotirmoi Aich",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000038Ugi5QAC/Profile_Picture_2022-04-15T07:48:28.png",biography:"Biotechnologist with 15 years of research including 6 years of teaching experience. Demonstrated record of scientific achievements through consistent publication record (H index = 13, with 874 citations) in high impact journals such as Nature Communications, Oncotarget, Annals of Oncology, PNAS, and AJRCCM, etc. Strong research professional with a post-doctorate from ACTREC where I gained experimental oncology experience in clinical settings and a doctorate from IGIB where I gained expertise in asthma pathophysiology. A well-trained biotechnologist with diverse experience on the bench across different research themes ranging from asthma to cancer and other infectious diseases. An individual with a strong commitment and innovative mindset. Have the ability to work on diverse projects such as regenerative and molecular medicine with an overall mindset of improving healthcare.",institutionString:"DY Patil Deemed to Be University",institution:null},{id:"349288",title:"Prof.",name:"Soumya",middleName:null,surname:"Basu",slug:"soumya-basu",fullName:"Soumya Basu",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000035QxIDQA0/Profile_Picture_2022-04-15T07:47:01.jpg",biography:"Soumya Basu, Ph.D., is currently working as an Associate Professor at Dr. D. Y. Patil Biotechnology and Bioinformatics Institute, Dr. D. Y. Patil Vidyapeeth, Pune, Maharashtra, India. With 16+ years of trans-disciplinary research experience in Drug Design, development, and pre-clinical validation; 20+ research article publications in journals of repute, 9+ years of teaching experience, trained with cross-disciplinary education, Dr. Basu is a life-long learner and always thrives for new challenges.\r\nHer research area is the design and synthesis of small molecule partial agonists of PPAR-γ in lung cancer. She is also using artificial intelligence and deep learning methods to understand the exosomal miRNA’s role in cancer metastasis. Dr. Basu is the recipient of many awards including the Early Career Research Award from the Department of Science and Technology, Govt. of India. She is a reviewer of many journals like Molecular Biology Reports, Frontiers in Oncology, RSC Advances, PLOS ONE, Journal of Biomolecular Structure & Dynamics, Journal of Molecular Graphics and Modelling, etc. She has edited and authored/co-authored 21 journal papers, 3 book chapters, and 15 abstracts. She is a Board of Studies member at her university. She is a life member of 'The Cytometry Society”-in India and 'All India Cell Biology Society”- in India.",institutionString:"Dr. D.Y. Patil Vidyapeeth, Pune",institution:{name:"Dr. D.Y. Patil Vidyapeeth, Pune",country:{name:"India"}}},{id:"354817",title:"Dr.",name:"Anubhab",middleName:null,surname:"Mukherjee",slug:"anubhab-mukherjee",fullName:"Anubhab Mukherjee",position:null,profilePictureURL:"https://intech-files.s3.amazonaws.com/0033Y0000365PbRQAU/ProfilePicture%202022-04-15%2005%3A11%3A18.480",biography:"A former member of Laboratory of Nanomedicine, Brigham and Women’s Hospital, Harvard University, Boston, USA, Dr. Anubhab Mukherjee is an ardent votary of science who strives to make an impact in the lives of those afflicted with cancer and other chronic/acute ailments. He completed his Ph.D. from CSIR-Indian Institute of Chemical Technology, Hyderabad, India, having been skilled with RNAi, liposomal drug delivery, preclinical cell and animal studies. He pursued post-doctoral research at College of Pharmacy, Health Science Center, Texas A & M University and was involved in another postdoctoral research at Department of Translational Neurosciences and Neurotherapeutics, John Wayne Cancer Institute, Santa Monica, California. In 2015, he worked in Harvard-MIT Health Sciences & Technology as a visiting scientist. He has substantial experience in nanotechnology-based formulation development and successfully served various Indian organizations to develop pharmaceuticals and nutraceutical products. He is an inventor in many US patents and an author in many peer-reviewed articles, book chapters and books published in various media of international repute. Dr. Mukherjee is currently serving as Principal Scientist, R&D at Esperer Onco Nutrition (EON) Pvt. Ltd. and heads the Hyderabad R&D center of the organization.",institutionString:"Esperer Onco Nutrition Pvt Ltd.",institution:null},{id:"319365",title:"Assistant Prof.",name:"Manash K.",middleName:null,surname:"Paul",slug:"manash-k.-paul",fullName:"Manash K. Paul",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/319365/images/system/319365.png",biography:"Manash K. Paul is a scientist and Principal Investigator at the University of California Los Angeles. He has contributed significantly to the fields of stem cell biology, regenerative medicine, and lung cancer. His research focuses on various signaling processes involved in maintaining stem cell homeostasis during the injury-repair process, deciphering the lung stem cell niche, pulmonary disease modeling, immuno-oncology, and drug discovery. He is currently investigating the role of extracellular vesicles in premalignant lung cell migration and detecting the metastatic phenotype of lung cancer via artificial intelligence-based analyses of exosomal Raman signatures. Dr. Paul also works on spatial multiplex immunofluorescence-based tissue mapping to understand the immune repertoire in lung cancer. Dr. Paul has published in more than sixty-five peer-reviewed international journals and is highly cited. He is the recipient of many awards, including the UCLA Vice Chancellor’s award and the 2022 AAISCR-R Vijayalaxmi Award for Innovative Cancer Research. He is a senior member of the Institute of Electrical and Electronics Engineers (IEEE) and an editorial board member for several international journals.",institutionString:"University of California Los Angeles",institution:{name:"University of California Los Angeles",country:{name:"United States of America"}}},{id:"311457",title:"Dr.",name:"Júlia",middleName:null,surname:"Scherer Santos",slug:"julia-scherer-santos",fullName:"Júlia Scherer Santos",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/311457/images/system/311457.jpg",biography:"Dr. Júlia Scherer Santos works in the areas of cosmetology, nanotechnology, pharmaceutical technology, beauty, and aesthetics. Dr. Santos also has experience as a professor of graduate courses. Graduated in Pharmacy, specialization in Cosmetology and Cosmeceuticals applied to aesthetics, specialization in Aesthetic and Cosmetic Health, and a doctorate in Pharmaceutical Nanotechnology. Teaching experience in Pharmacy and Aesthetics and Cosmetics courses. She works mainly on the following subjects: nanotechnology, cosmetology, pharmaceutical technology, aesthetics.",institutionString:"Universidade Federal de Juiz de Fora",institution:{name:"Universidade Federal de Juiz de Fora",country:{name:"Brazil"}}},{id:"219081",title:"Dr.",name:"Abdulsamed",middleName:null,surname:"Kükürt",slug:"abdulsamed-kukurt",fullName:"Abdulsamed Kükürt",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/219081/images/system/219081.png",biography:"Dr. Kükürt graduated from Uludağ University in Turkey. He started his academic career as a Research Assistant in the Department of Biochemistry at Kafkas University. In 2019, he completed his Ph.D. program in the Department of Biochemistry at the Institute of Health Sciences. He is currently working at the Department of Biochemistry, Kafkas University. He has 27 published research articles in academic journals, 11 book chapters, and 37 papers. He took part in 10 academic projects. He served as a reviewer for many articles. He still serves as a member of the review board in many academic journals. He is currently working on the protective activity of phenolic compounds in disorders associated with oxidative stress and inflammation.",institutionString:null,institution:{name:"Kafkas University",country:{name:"Turkey"}}},{id:"178366",title:"Dr.",name:"Volkan",middleName:null,surname:"Gelen",slug:"volkan-gelen",fullName:"Volkan Gelen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/178366/images/system/178366.jpg",biography:"Volkan Gelen is a Physiology specialist who received his veterinary degree from Kafkas University in 2011. Between 2011-2015, he worked as an assistant at Atatürk University, Faculty of Veterinary Medicine, Department of Physiology. In 2016, he joined Kafkas University, Faculty of Veterinary Medicine, Department of Physiology as an assistant professor. Dr. Gelen has been engaged in various academic activities at Kafkas University since 2016. There he completed 5 projects and has 3 ongoing projects. He has 60 articles published in scientific journals and 20 poster presentations in scientific congresses. His research interests include physiology, endocrine system, cancer, diabetes, cardiovascular system diseases, and isolated organ bath system studies.",institutionString:"Kafkas University",institution:{name:"Kafkas University",country:{name:"Turkey"}}},{id:"418963",title:"Dr.",name:"Augustine Ododo",middleName:"Augustine",surname:"Osagie",slug:"augustine-ododo-osagie",fullName:"Augustine Ododo Osagie",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/418963/images/16900_n.jpg",biography:"Born into the family of Osagie, a prince of the Benin Kingdom. I am currently an academic in the Department of Medical Biochemistry, University of Benin. Part of the duties are to teach undergraduate students and conduct academic research.",institutionString:null,institution:{name:"University of Benin",country:{name:"Nigeria"}}},{id:"192992",title:"Prof.",name:"Shagufta",middleName:null,surname:"Perveen",slug:"shagufta-perveen",fullName:"Shagufta Perveen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/192992/images/system/192992.png",biography:"Prof. Shagufta Perveen is a Distinguish Professor in the Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. Dr. Perveen has acted as the principal investigator of major research projects funded by the research unit of King Saud University. She has more than ninety original research papers in peer-reviewed journals of international repute to her credit. She is a fellow member of the Royal Society of Chemistry UK and the American Chemical Society of the United States.",institutionString:"King Saud University",institution:{name:"King Saud University",country:{name:"Saudi Arabia"}}},{id:"49848",title:"Dr.",name:"Wen-Long",middleName:null,surname:"Hu",slug:"wen-long-hu",fullName:"Wen-Long Hu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/49848/images/system/49848.jpg",biography:"Wen-Long Hu is Chief of the Division of Acupuncture, Department of Chinese Medicine at Kaohsiung Chang Gung Memorial Hospital, as well as an adjunct associate professor at Fooyin University and Kaohsiung Medical University. Wen-Long is President of Taiwan Traditional Chinese Medicine Medical Association. He has 28 years of experience in clinical practice in laser acupuncture therapy and 34 years in acupuncture. He is an invited speaker for lectures and workshops in laser acupuncture at many symposiums held by medical associations. He owns the patent for herbal preparation and producing, and for the supercritical fluid-treated needle. Dr. Hu has published three books, 12 book chapters, and more than 30 papers in reputed journals, besides serving as an editorial board member of repute.",institutionString:"Kaohsiung Chang Gung Memorial Hospital",institution:{name:"Kaohsiung Chang Gung Memorial Hospital",country:{name:"Taiwan"}}},{id:"298472",title:"Prof.",name:"Andrey V.",middleName:null,surname:"Grechko",slug:"andrey-v.-grechko",fullName:"Andrey V. Grechko",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/298472/images/system/298472.png",biography:"Andrey Vyacheslavovich Grechko, Ph.D., Professor, is a Corresponding Member of the Russian Academy of Sciences. He graduated from the Semashko Moscow Medical Institute (Semashko National Research Institute of Public Health) with a degree in Medicine (1998), the Clinical Department of Dermatovenerology (2000), and received a second higher education in Psychology (2009). Professor A.V. Grechko held the position of Сhief Physician of the Central Clinical Hospital in Moscow. He worked as a professor at the faculty and was engaged in scientific research at the Medical University. Starting in 2013, he has been the initiator of the creation of the Federal Scientific and Clinical Center for Intensive Care and Rehabilitology, Moscow, Russian Federation, where he also serves as Director since 2015. He has many years of experience in research and teaching in various fields of medicine, is an author/co-author of more than 200 scientific publications, 13 patents, 15 medical books/chapters, including Chapter in Book «Metabolomics», IntechOpen, 2020 «Metabolomic Discovery of Microbiota Dysfunction as the Cause of Pathology».",institutionString:"Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology",institution:null},{id:"199461",title:"Prof.",name:"Natalia V.",middleName:null,surname:"Beloborodova",slug:"natalia-v.-beloborodova",fullName:"Natalia V. Beloborodova",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/199461/images/system/199461.jpg",biography:'Natalia Vladimirovna Beloborodova was educated at the Pirogov Russian National Research Medical University, with a degree in pediatrics in 1980, a Ph.D. in 1987, and a specialization in Clinical Microbiology from First Moscow State Medical University in 2004. She has been a Professor since 1996. Currently, she is the Head of the Laboratory of Metabolism, a division of the Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russian Federation. N.V. Beloborodova has many years of clinical experience in the field of intensive care and surgery. She studies infectious complications and sepsis. She initiated a series of interdisciplinary clinical and experimental studies based on the concept of integrating human metabolism and its microbiota. Her scientific achievements are widely known: she is the recipient of the Marie E. Coates Award \\"Best lecturer-scientist\\" Gustafsson Fund, Karolinska Institutes, Stockholm, Sweden, and the International Sepsis Forum Award, Pasteur Institute, Paris, France (2014), etc. Professor N.V. Beloborodova wrote 210 papers, five books, 10 chapters and has edited four books.',institutionString:"Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology",institution:null},{id:"354260",title:"Ph.D.",name:"Tércio Elyan",middleName:"Azevedo",surname:"Azevedo Martins",slug:"tercio-elyan-azevedo-martins",fullName:"Tércio Elyan Azevedo Martins",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/354260/images/16241_n.jpg",biography:"Graduated in Pharmacy from the Federal University of Ceará with the modality in Industrial Pharmacy, Specialist in Production and Control of Medicines from the University of São Paulo (USP), Master in Pharmaceuticals and Medicines from the University of São Paulo (USP) and Doctor of Science in the program of Pharmaceuticals and Medicines by the University of São Paulo. Professor at Universidade Paulista (UNIP) in the areas of chemistry, cosmetology and trichology. Assistant Coordinator of the Higher Course in Aesthetic and Cosmetic Technology at Universidade Paulista Campus Chácara Santo Antônio. Experience in the Pharmacy area, with emphasis on Pharmacotechnics, Pharmaceutical Technology, Research and Development of Cosmetics, acting mainly on topics such as cosmetology, antioxidant activity, aesthetics, photoprotection, cyclodextrin and thermal analysis.",institutionString:null,institution:{name:"University of Sao Paulo",country:{name:"Brazil"}}},{id:"334285",title:"Ph.D. Student",name:"Sameer",middleName:"Kumar",surname:"Jagirdar",slug:"sameer-jagirdar",fullName:"Sameer Jagirdar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/334285/images/14691_n.jpg",biography:"I\\'m a graduate student at the center for biosystems science and engineering at the Indian Institute of Science, Bangalore, India. I am interested in studying host-pathogen interactions at the biomaterial interface.",institutionString:null,institution:{name:"Indian Institute of Science Bangalore",country:{name:"India"}}},{id:"329248",title:"Dr.",name:"Md. Faheem",middleName:null,surname:"Haider",slug:"md.-faheem-haider",fullName:"Md. Faheem Haider",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/329248/images/system/329248.jpg",biography:"Dr. Md. Faheem Haider completed his BPharm in 2012 at Integral University, Lucknow, India. In 2014, he completed his MPharm with specialization in Pharmaceutics at Babasaheb Bhimrao Ambedkar University, Lucknow, India. He received his Ph.D. degree from Jamia Hamdard University, New Delhi, India, in 2018. He was selected for the GPAT six times and his best All India Rank was 34. Currently, he is an assistant professor at Integral University. Previously he was an assistant professor at IIMT University, Meerut, India. He has experience teaching DPharm, Pharm.D, BPharm, and MPharm students. He has more than five publications in reputed journals to his credit. Dr. Faheem’s research area is the development and characterization of nanoformulation for the delivery of drugs to various organs.",institutionString:"Integral University",institution:{name:"Integral University",country:{name:"India"}}},{id:"329795",title:"Dr.",name:"Mohd Aftab",middleName:"Aftab",surname:"Siddiqui",slug:"mohd-aftab-siddiqui",fullName:"Mohd Aftab Siddiqui",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/329795/images/system/329795.png",biography:"Dr. Mohd Aftab Siddiqui is an assistant professor in the Faculty of Pharmacy, Integral University, Lucknow, India, where he obtained a Ph.D. in Pharmacology in 2020. He also obtained a BPharm and MPharm from the same university in 2013 and 2015, respectively. His area of research is the pharmacological screening of herbal drugs/natural products in liver cancer and cardiac diseases. He is a member of many professional bodies and has guided many MPharm and PharmD research projects. Dr. Siddiqui has many national and international publications and one German patent to his credit.",institutionString:"Integral University",institution:null}]}},subseries:{item:{id:"15",type:"subseries",title:"Chemical Biology",keywords:"Phenolic Compounds, Essential Oils, Modification of Biomolecules, Glycobiology, Combinatorial Chemistry, Therapeutic peptides, Enzyme Inhibitors",scope:"Chemical biology spans the fields of chemistry and biology involving the application of biological and chemical molecules and techniques. In recent years, the application of chemistry to biological molecules has gained significant interest in medicinal and pharmacological studies. This topic will be devoted to understanding the interplay between biomolecules and chemical compounds, their structure and function, and their potential applications in related fields. Being a part of the biochemistry discipline, the ideas and concepts that have emerged from Chemical Biology have affected other related areas. This topic will closely deal with all emerging trends in this discipline.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/15.jpg",hasOnlineFirst:!0,hasPublishedBooks:!0,annualVolume:11411,editor:{id:"441442",title:"Dr.",name:"Şükrü",middleName:null,surname:"Beydemir",slug:"sukru-beydemir",fullName:"Şükrü Beydemir",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003GsUoIQAV/Profile_Picture_1634557147521",biography:"Dr. Şükrü Beydemir obtained a BSc in Chemistry in 1995 from Yüzüncü Yıl University, MSc in Biochemistry in 1998, and PhD in Biochemistry in 2002 from Atatürk University, Turkey. He performed post-doctoral studies at Max-Planck Institute, Germany, and University of Florence, Italy in addition to making several scientific visits abroad. He currently works as a Full Professor of Biochemistry in the Faculty of Pharmacy, Anadolu University, Turkey. Dr. Beydemir has published over a hundred scientific papers spanning protein biochemistry, enzymology and medicinal chemistry, reviews, book chapters and presented several conferences to scientists worldwide. He has received numerous publication awards from various international scientific councils. He serves in the Editorial Board of several international journals. 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