Open access peer-reviewed Edited Volume

Translational Research in Cancer

Edited by Sivapatham Sundaresan

SRM Institute of Science and Technology

Co-editor:

Yeun-Hwa Gu

Junshin Gakuen University

Translational research in oncology benefits from an abundance of knowledge resulting from genome-scale studies concerning the molecular pathways involved in tumorigenesis. Translational oncology represents a bridge between basic research and clinical practice in cancer medicine. The vast majority of cancer cases are due to environmental risk factors. Many of these environmental factors are controllable lifestyle choices. Experimental cancer treatments are studied in clinical trials to compare the proposed treatment to the best existing treatment through translational research. The key features of the book include: 1) New screening for the development of radioprotectors: radioprotection and anti-cancer effect of β-Glucan (Enterococcus faecalis) 2) Translational perspective on hepatocellular carcinoma 3) Brachytherapy for endometrial cancer 4) Discovery of small molecule inhibitors for histone methyltransferases in cancer

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Translational Research in CancerEdited by Sivapatham Sundaresan

Published: February 3rd 2021

DOI: 10.5772/intechopen.73772

ISBN: 978-1-83880-535-7

Print ISBN: 978-1-83880-534-0

eBook (PDF) ISBN: 978-1-78984-837-3

Copyright year: 2021

Books open for chapter submissions

1467 Total Chapter Downloads

chaptersDownloads

Open access peer-reviewed

1. Discovery of Small Molecule Inhibitors for Histone Methyltransferases in Cancer

By Aishat A. Motolani, Mengyao Sun, Matthew Martin, Steven Sun and Tao Lu

170

Open access peer-reviewed

2. IL10 as Cancer Biomarker

By Maria Teresa Gonzalez-Garza, Delia Elva Cruz-Vega and Carmen Maldonado-Bernal

142

Open access peer-reviewed

3. Ion Channels and Transporters as Cancer Biomarkers and Targets for Diagnostics with Antibodies

By Jessica Iorio, Claudia Duranti and Elena Lastraioli

126

Open access peer-reviewed

4. Translational Perspective in Hepatocellular Carcinoma

By Sivapatham Sundaresan and Palanirasu Rajapriya

114

Open access peer-reviewed

5. Chalcones: Potential Anticancer Agents

By Adam McCluskey and Cecilia Russell

52

Open access peer-reviewed

6. New Screening for the Development of Radioprotectors: Radioprotection and Anti-Cancer Effect of β-Glucan (Enterococcus faecalis)

By Yeun-Hwa Gu

77

Open access peer-reviewed

7. Evaluation by Monte Carlo Simulation of Doses Distribution in Tumors with Hypoxia

By Mirko Salomón Alva-Sánchez and Thatiane Alves Pianoschi

103

Open access peer-reviewed

8. Bozepinib: A Promising Selective Derivative Targeting Breast Cancer Stem Cells

By Joaquín M. Campos, Ana Conejo-García and Olga Cruz-López

147

Open access peer-reviewed

9. NQO1-Bioactivatable Therapeutics as Radiosensitizers for Cancer Treatment

By Naveen Singh, Edward A. Motea, Xiumei Huang, Colton L. Starcher, Jayne Silver, I-Ju Yeh, S. Louise Pay, Xiaolin Su, Kristen A. Russ, David A. Boothman and Erik A. Bey

151

Open access peer-reviewed

10. Brachytherapy in Endometrial Cancer

By Mehmet Sait Bakir

102

Open access peer-reviewed

11. Acquisition and Management of Data for Translational Science in Oncology

By Thomas J. FitzGerald, Maryann Bishop-Jodoin, Fran Laurie, Richard Hanusik, Matthew Iandoli, Kathryn Karolczuk, Sandra Kessel, Fred Prior, Joel Saltz, Ashish Sharma, Michael Knopp, Mark Rosen, Ying Xiao, David Followill, Jeff Michalski, Ameer Elaimy, James Shen, Peter Lee, Maria Giulia Cicchetti and Janaki Moni

157

Open access peer-reviewed

12. Implications of Radiosensitizer and Radioprotector Factors in Refining the Dose-Volume Constraints and Radiobiological Models

By Camil Ciprian Mirestean, Călin Gheorghe Buzea, Roxana Irina Iancu and Dragoș Petru Teodor Iancu

140

Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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