Open access peer-reviewed Edited Volume

Selected Chapters from the Renin-Angiotensin System

Edited by Aleksandar Kibel

Osijek University Hospital

Selected Chapters from the Renin-Angiotensin System aims to provide a comprehensive overview of the most important physiological and pathophysiological roles of the renin-angiotensin system (RAS). The complex and convoluted RAS has been investigated for many years and, through rigorous scientific research, many important and previously unknown components and functions of the RAS have come to light. These discoveries have been crucial in the understanding of this system and provide a basis for effective modulation of the system as part of therapeutic strategies for a number of widespread disorders. New studies are continuing to elucidate the RAS and the mechanisms associated with its functions. This book discusses relevant scientific knowledge about the RAS and intends to introduce the reader to cutting-edge research with an accentuation on the mechanisms at the functional/physiological and molecular/cellular levels.

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Selected Chapters from the Renin-Angiotensin SystemEdited by Aleksandar Kibel

Published: August 19th 2020

DOI: 10.5772/intechopen.77666

ISBN: 978-1-78985-422-0

Print ISBN: 978-1-78985-421-3

eBook (PDF) ISBN: 978-1-78985-554-8

Copyright year: 2020

Books open for chapter submissions

3085 Total Chapter Downloads

1 Crossref Citations

5 Dimensions Citations


Open access peer-reviewed

1. From Angiotensin to Renin to Prorenin and from the Adrenal to the Kidney to the Placenta and the Lungs: An Historical Journey

By Alan Poisner


Open access peer-reviewed

2. The Renin-Angiotensin-Aldosterone System: Genomics, Proteomics and Therapeutic Implications

By Manuela Ciocoiu, Iris Bararu-Bojan, Maria Vladeanu and Codruta Badescu


Open access peer-reviewed

3. Significance of the Renin-Angiotensin System in Clinical Conditions

By Vedran Đambić, Đorđe Pojatić, Anto Stažić and Aleksandar Kibel


Open access peer-reviewed

4. Treatment of Essential Hypertension with Emphasis in the Renin-Angiotensin System: How to Prevent Secondary Outcomes without Adding Fuel to the Fire

By Gabriel Lucca de Oliveira Salvador


Open access peer-reviewed

5. The Intratubular and Intracrine Renin-Angiotensin System in the Proximal Tubules of the Kidney and Its Roles in Angiotensin II-Induced Hypertension

By Xiao C. Li, Ana Paula de Oliveira Leite, Xu Chen, Chunling Zhao, Xiaowen Zheng, Jianfeng Zhang and Jia L. Zhuo


Open access peer-reviewed

6. Scientific Evidences Supporting the Activation of the Renin-Angiotensin-Aldosterone System during Estral Cycle and Pregnancy in Mares

By Katy Satué and Ana Muñoz


Open access peer-reviewed

7. Connexin-Based Channels and RhoA/ROCK Pathway in Angiotensin II-Induced Kidney Damage

By Gonzalo I. Gómez, Victoria Velarde and Juan C. Sáez


Open access peer-reviewed

8. The Potential Role of Renin Angiotensin System (RAS) and Dipeptidyl Peptidase-4 (DPP-4) in COVID-19: Navigating the Uncharted

By Hayder M. Al-Kuraishy, Marwa S. Al-Niemi, Nawar R. Hussain, Ali I. Al-Gareeb, Nasser A. Al-Harchan and Azhar H. Al-Kurashi


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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