Open access peer-reviewed Edited Volume

Neoplasm

Edited by Hafiz Shahzad

University of the Punjab, Pakistan

Neoplasm refers to an abnormal tissue growth that arises as a consequence of rapid cell proliferation and continues to grow abnormally even after terminating the stimuli that had instigated the change. It lacks partial or complete functional coordination with that of the normal tissues. Neoplasms are classified depending on the degree and type of tissues involved. Carcinogenesis is a multistep process where a plethora of endogenous and exogenous factors turns out genetic and epigenetic modifications, which collectively amend some critical cellular pathways controlling the proliferation, apoptosis, and differentiation. The cells having aberrant modifications are transformed into malignant ones of which the clonal expansion results in the development of cancer. This book provides the reader with a comprehensive overview of various cancer types along with their molecular mechanisms of initiation and progression. It also describes the current knowledge about the state-of-the-art measures being employed in cancer diagnosis and therapeutics. Particular attention is paid to make this book equally useful for students, practitioners, and expert scientists.

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IntechOpen
NeoplasmEdited by Hafiz Shahzad

Published: September 19th 2018

DOI: 10.5772/intechopen.69560

ISBN: 978-1-78923-778-8

Print ISBN: 978-1-78923-777-1

Copyright year: 2018

Books open for chapter submissions

2026 Total Chapter Downloads

chaptersDownloads

Open access peer-reviewed

1. Neoplasms of Central Nervous System: A Diagnostic Approach

By Frank Yuan Shan, Dingrong Zhong, Wanming Hu, Nitesh Patel, Ekokobe Fonkem, Dongxia Feng, Yilu Zhang, Jason H. Huang and Arundhati Rao

225

Open access peer-reviewed

2. Uterine Sarcomas: An Updated Overview. Part 1: Smooth Muscle Tumors

By Roberta Zappacosta, Francesco Fanfani, Barbara Zappacosta, Francesca Sablone, Lucia Pansa, Marco Liberati and Sandra Rosini

203

Open access peer-reviewed

3. Uterine Sarcomas: An Updated Overview Part 2: Endometrial Stromal Tumor

By Roberta Zappacosta, Francesco Fanfani, Barbara Zappacosta, Francesca Sablone, Lucia Pansa, Marco Liberati and Sandra Rosini

189

Open access peer-reviewed

4. Novel Mechanism of Nonalcoholic Lipid Accumulation Promoting Malignant Transformation of Hepatocytes

By Min Yao, Wenjie Zheng, Li Wang, Miao Fang, Zhizhen Dong and Dengfu Yao

235

Open access peer-reviewed

5. Glucose Metabolism and Carcinogenesis: The Impact of the Tumor Suppressor p53

By Monde Ntwasa and Ubanako Njende

223

Open access peer-reviewed

6. An Overview of Cancer Treatment Modalities

By Zaigham Abbas and Sakina Rehman

386

Open access peer-reviewed

7. Biomarker-Based Targeted Therapeutics

By Shainan Hora, Amit Kumar Pandey and Sudhakar Jha

231

Open access peer-reviewed

8. Targeting the Ubiquitin Proteasome System in Cancer

By Nishi Kumari, Kwok Kin Lee and Sudhakar Jha

334

Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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