Open access peer-reviewed Edited Volume

Cardiotoxicity of Oncologic Treatments

The possibility of getting a cardiovascular disease or cancer increases with advancing age. At the same time, relevant improvements in cancer therapy have resulted in the improvement of quality of life and the increasement of the survival rate of such patients. As a result we have larger number of patients that experience the cardiac side effects of chemotherapy. The extent of cardiotoxicity is variable, depending on the type of drug used, combination with other drugs, prior mediastinal radiotherapy and the presence of cardiovascular risk factors or history of heart disease. Early detection of the patients proneness for developing cardiotoxicity is the key issue to decrease morbidity and mortality. It also facilitates more tailored therapeutic interventions. Therefore, the collaboration and interaction of cardiology and oncology may contribute to reducing the cardiovascular adverse effects and improving the results in the treatment of patients with cancer.

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Cardiotoxicity of Oncologic TreatmentsEdited by Manuela Fiuza

Published: March 28th 2012

DOI: 10.5772/2170

ISBN: 978-953-51-0273-1

eBook (PDF) ISBN: 978-953-51-6893-5

Copyright year: 2012

Books open for chapter submissions

17489 Total Chapter Downloads

8 Crossref Citations

26 Web of Science Citations

29 Dimensions Citations


Open access peer-reviewed

1. Cardiovascular Pathophysiology Produced by Natural Toxins and Their Possible Therapeutic Implications

By Robert Frangež, Marjana Grandič and Milka Vrecl


Open access peer-reviewed

2. Role of Nitric Oxide in Isoproterenol-Induced Myocardial Infarction

By Victoria Chagoya de Sánchez, Lucía Yañez-Maldonado, Susana Vidrio-Gómez, Lidia Martínez, Jorge Suárez, Alberto Aranda-Fraustro, Juan Carlos Torres and Gabriela Velasco-Loyden


Open access peer-reviewed

3. Cardiac Complications of Cancer Treatment

By Beata Mlot and Piotr Rzepecki


Open access peer-reviewed

4. Neuregulin1-ErbB Signaling in Doxorubicin-Induced Cardiotoxicity

By David Goukassian, James Morgan and Xinhua Yan


Open access peer-reviewed

5. Doxorubicin-Induced Oxidative Injury of Cardiomyocytes - Do We Have Right Strategies for Prevention?

By Vukosava Milic Torres and Viktorija Dragojevic Simic


Open access peer-reviewed

6. Trastuzumab and Cardiotoxicity

By M. Fiuza and A. Magalhães


Open access peer-reviewed

7. Early Detection and Prediction of Cardiotoxicity - Biomarker and Echocardiographic Evaluation

By Elena Kinova and Assen Goudev


Edited Volume and chapters are indexed in

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