Open access peer-reviewed Edited Volume

Cholesterol Lowering Therapies and Drugs

Edited by Chunfa Huang

Saint Louis University, United States of America


Using natural products and developing pharmaceutical drugs are emerging topics to reduce blood cholesterol levels for preventing heart disease and stroke. Covering recent progresses in cholesterol-lowering drugs and therapy, this book describes the natural and pharmaceutical products that are in clinical uses to lower cholesterol and lipids and compares these drugs in responses to different diseases such as homozygous familial hypercholesterolemia, atherosclerosis, cardiovascular disease, and cancer. The relationship between ethnicity and cholesterol-lowering drug responses is also reviewed. Each chapter is a building block for the book, but each individual chapter is also a complete subject package for the readers. Researchers from basic and clinic science interested in lipid and cholesterol metabolism, regulation, and lowering will find this book very useful. Features: - Up-to-date information of the molecular mechanisms of cholesterol lowering, the drugs from natural and pharmaceutical products, and their associated therapeutic strategies in human diseases. - Discussion of the pathogenesis of several human diseases, which are associated with high cholesterol levels and evaluation of the results of different cholesterol-lowering drug treatment in these diseases. - Discussion of the combinations of cancer chemotherapy and cholesterol lowering in potential cancer treatment and cancer prevention by cholesterol-lowering drugs. - Critical analysis of the effect of ethnicity on responses to cholesterol-lowering drug therapy leading to rational dose adjustment of cholesterol-lowering drugs for different people use.

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Cholesterol Lowering Therapies and DrugsEdited by Chunfa Huang

Published: October 26th 2016

DOI: 10.5772/61647

ISBN: 978-953-51-2735-2

Print ISBN: 978-953-51-2734-5

eBook (PDF) ISBN: 978-953-51-4166-2

Copyright year: 2016

Books open for chapter submissions

11244 Total Chapter Downloads

1 Crossref Citations

5 Web of Science Citations

3 Dimensions Citations


Open access peer-reviewed

1. Natural Cholesterol Busters

By Gamaleldin I. Harisa, Sabry M. Attia and Gamil M. Abd Allah


Open access peer-reviewed

2. Intracellular Cholesterol Lowering as Novel Target for Anti‐Atherosclerotic Therapy

By Alexander N. Orekhov and Ekaterina A. Ivanova


Open access peer-reviewed

3. Influence of Atorvastatin on Plasma Atherogenic Biomarkers

By Marek Kucera, Stanislav Oravec and Ludovit Gaspar


Open access peer-reviewed

4. Treatment of Homozygous Familial Hypercholesterolemia: Challenges and Latest Development

By Min‐Ji Charng


Open access peer-reviewed

5. Cholesterol-Lowering Drugs and Therapies in Cardiovascular Disease

By Zaid Almarzooq and Parmanand Singh


Open access peer-reviewed

6. Cholesterol Lowering in Cancer Prevention and Therapy

By Chunfa Huang and Carl E. Freter


Open access peer-reviewed

7. Ethnicity and Response to Drug Therapy

By Maha M. Alrasheed and Nduna Dzimiri


Edited Volume and chapters are indexed in

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