Open access peer-reviewed Edited Volume

Protein Kinases

Promising Targets for Anticancer Drug Research

Edited by Rajesh K. Singh

Punjab Technical University

For the past two decades, the protein kinase family has been an intense area of research for developing anticancer drugs. Despite tremendous advancements in kinase drug expansion, many kinases are still unexplored. As such, this book includes research and review articles from experts that focus on protein kinase signalling pathways as a molecular drug target. Chapters include illustrations and cover such topics as the mechanism of action and anticancer activity of protein kinase inhibitors on various cancer types. They also discuss new opportunities, challenges, and future perspectives in the field.

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Protein KinasesPromising Targets for Anticancer Drug ResearchEdited by Rajesh K. Singh

Published: December 8th 2021

DOI: 10.5772/intechopen.82939

ISBN: 978-1-83880-907-2

Print ISBN: 978-1-83880-906-5

eBook (PDF) ISBN: 978-1-83880-908-9

Copyright year: 2021

Books open for chapter submissions

896 Total Chapter Downloads

1 Crossref Citations

1 Dimensions Citations

chaptersDownloads

Open access peer-reviewed

1. Introductory Chapter: Protein Kinases as Promising Targets for Drug Design against Cancer

By Rohit Bhatia and Rajesh K. Singh

48

Open access peer-reviewed

2. Protein Kinase Inhibitors - Selectivity or Toxicity?

By Moran Grossman and Elaine Adler

170

Open access peer-reviewed

3. Using the Structural Kinome to Systematize Kinase Drug Discovery

By Zheng Zhao and Philip E. Bourne

95

Open access peer-reviewed

4. Time Series Analysis on the Conformational Change of c-Src Tyrosine Kinase

By Hyun Jung Yoon, Sungmin Lee, Suhyun Park and Sangwook Wu

137

Open access peer-reviewed

5. Importance of Protein Kinase and Its Inhibitor: A Review

By Panneerselvam Theivendren, Selvaraj Kunjiappan, Yashoda Mariappa Hegde, Sivakumar Vellaichamy, Murugananthan Gopal, Senthil Rajan Dhramalingam and Sattanathan Kumar

219

Open access peer-reviewed

6. Recent Advances in the Therapeutic Development of Receptor Tyrosine Kinases (RTK) against Different Types of Cancer

By Somi Patranabis

143

Open access peer-reviewed

7. The Role of Kinase Inhibitors in Cancer Therapies

By Gizem Kursunluoglu, Duygu Erdogan, Elcin Cagatay, Esra Bulut Atalay, Seminay Guler, Yonca Gungor and Hulya Ayar Kayali

85

Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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