Open access peer-reviewed Edited Volume


Edited by Payam Behzadi

Shahr-e-Qods Branch, Islamic Azad University

The human immune system is a complicated biological network that employs a collection of cells, molecules, and proteins. Cytokines play an important role in regulating the innate and adaptive immune systems by different receptors and signaling pathways. As such, they are also implicated in the occurrence of different disorders and diseases. This book presents a comprehensive overview of immunology, the immune system, and cytokines. Chapters cover such topics as the role and importance of tumor necrosis factor (TNF) in the human body, the association of cytokines with different disorders and diseases, and the role of cytokines in dentistry.

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CytokinesEdited by Payam Behzadi

Published: August 19th 2020

DOI: 10.5772/intechopen.77671

ISBN: 978-1-78984-859-5

Print ISBN: 978-1-78984-858-8

eBook (PDF) ISBN: 978-1-83968-339-8

Copyright year: 2020

Books open for chapter submissions

4878 Total Chapter Downloads

5 Crossref Citations

11 Dimensions Citations


Open access peer-reviewed

1. Introductory Chapter: Cytokines - The Diamonds and Pearls of Biological Systems

By Márió Gajdács and Payam Behzadi


Open access peer-reviewed

2. In vitro Cell-Based Assays for Potency Testing of Anti-TNF-α Biological Drugs

By Sara Žigon-Branc, Ariana Barlič and Matjaž Jeras


Open access peer-reviewed

3. Tumor Necrosis Factor Alpha: A Major Cytokine of Brain Neuroinflammation

By Mubarak Muhammad


Open access peer-reviewed

4. TNFR2 and Regulatory T Cells: Potential Immune Checkpoint Target in Cancer Immunotherapy

By Xuehui He and Xinhui Wang


Open access peer-reviewed

5. Innate Immunity and Neuroinflammation in Neuropsychiatric Conditions Including Autism Spectrum Disorders: Role of Innate Immune Memory

By Harumi Jyonouchi


Open access peer-reviewed

6. Cytokines in Scar Glial Formation after an Acute and Chronic Spinal Cord Injury

By Roxana Rodrígez-Barrera, Adrián Flores-Romero, Julián García-Sánchez, Lisset Karina Navarro-Torres, Marcela Garibay-López and Elisa García-Vences


Open access peer-reviewed

7. The Genetic Aspects of Behçet’s Disease: Role of Cytokine Genes Polymorphisms

By Abdulrahman Al Asmari and Misbahul Arfin


Open access peer-reviewed

8. IL-21 Signaling and Induction of Cytokine Expression in Human Leukemia Cells and Monocytes

By Chantel F. Faqua, Richard Akomeah and Samuel Evans Adunyah


Open access peer-reviewed

9. Cytokines’ Involvement in Periodontal Changes

By Petra Surlin, Liliana Foia, Sorina Solomon, Dora Maria Popescu, Dorin Nicolae Gheorghe, Adrian Camen, Maria Alexandra Martu, Anne Marie Rauten, Madalina Olteanu, Allma Pitru, Vasilica Toma, Simona Popa, Mihail Virgil Boldeanu, Silvia Martu and Ion Rogoveanu


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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