Open access peer-reviewed Edited Volume

Clinical Management of Shock

The Science and Art of Physiological Restoration

Edited by Stanislaw P. Stawicki

St. Luke's University Health Network


Mamta Swaroop

Northwestern University

Shock is a physiological state of war! From a healthcare provider perspective, the word “shock” is associated with a mixed array of feelings, including dread, well-founded fear, and deep respect. The physiological state of shock is well recognized for the associated destructive consequences, and its successful management requires prompt identification, immediate action, and sustained effort by all members of the healthcare team. This mindset of advanced preparation and constant readiness constitutes the foundation of the modern approach toward shock – early detection and prompt treatment for optimal outcomes. Despite the heterogeneity of “shock” as a clinico-pathological entity, there are some common threads that permeate all forms and manifestations of shock, with apparent increase in observed commonalities in the more advanced (and often irreversible) stages of the systemic syndrome. When faced with shock, the body and its systems do their best to compensate for the maldistribution of oxygen and nutrients. This is known as the so-called compensated shock. Beyond that, the body loses its ability to adjust any further, thus descending into “uncompensated shock,” with a refractory state characterized by vasoplegia and irreversible cardiovascular failure. As the reader journeys through the chapters of the book, he or she will read about various biomarkers and endpoints of resuscitation, explore different types of shock (e.g., septic, hemorrhagic, anaphylactic) and learn about some of the less often discussed topics such as neurogenic and spinal shock, as well as the amniotic fluid embolism. Our goals were to keep things clinically relevant and practically oriented, thus enabling the reader to apply the newly acquired knowledge in their everyday clinical routines. As the reader progresses through the book, we hope to help stimulate further discourse and innovative thinking about the topic. In this context, it is critical that basic, translational, and clinical research on shock continues to advance. Only through ongoing scientific progress can we help improve outcomes for patients with both rare and common forms of shock.

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Clinical Management of ShockThe Science and Art of Physiological RestorationEdited by Stanislaw P. Stawicki

Published: June 24th 2020

DOI: 10.5772/intechopen.73805

ISBN: 978-1-83881-171-6

Print ISBN: 978-1-83881-170-9

eBook (PDF) ISBN: 978-1-83881-172-3

Copyright year: 2020

Books open for chapter submissions

10960 Total Chapter Downloads

2 Crossref Citations

4 Dimensions Citations


Open access peer-reviewed

1. Introductory Chapter: Shock is a Physiological State of War

By Stanislaw P. Stawicki, Thomas J. Papadimos and Mamta Swaroop


Open access peer-reviewed

2. New Biomarkers of Sepsis with Clinical Relevance

By Débora Maria da Gomes Cunha, Guilherme Galdino da Silva and Mike Yoshio Hamasaki


Open access peer-reviewed

3. Resuscitation Endpoints in Traumatic Shock: A Focused Review with Emphasis on Point-of-Care Approaches

By Kathryn C. Kelley, Kyle Dammann, Alex Alers, Thomas B. Zanders, Charles Bendas and Stanislaw P. Stawicki


Open access peer-reviewed

4. Hemorrhagic Shock

By Fevzi Sarper Türker


Open access peer-reviewed

5. Sepsis and Septic Shock

By Alaap Mehta, Ali Khalid and Mamta Swaroop


Open access peer-reviewed

6. Anaphylactic Shock

By Stephen DeTurk, Shravan Reddy, Anna Ng Pellegrino and John Wilson


Open access peer-reviewed

7. Neurogenic Shock

By Anna Volski and Daniel J. Ackerman


Open access peer-reviewed

8. Spinal Shock: Differentiation from Neurogenic Shock and Key Management Approaches

By Keith Conti, Vikas Yellapu, Joan Sweeney, Steven M. Falowski and Stanislaw P. Stawicki


Open access peer-reviewed

9. Amniotic Fluid Embolism

By Neesaytee Boulden, Joseph Bell, Jose Rojas-Suarez and Jorge E. Tolosa


Open access peer-reviewed

10. Burn Shock and Resuscitation: Many Priorities, One Goal

By John Sojka, Andrew C. Krakowski and Stanislaw P. Stawicki


Open access peer-reviewed

11. Urosepsis: Flow is Life

By Nissar Shaikh, Umm-E-Amara, Jazib Hassan, Zeeshan Qazi, Arshad Chanda, Zia Mahemood, Mahommad Zubair, AR Raju Vegensa, Abdul Gafoor M. Tharayil, Adel Ganaw, Ranjan Matthias and Muna Al Musalmani


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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