Open access peer-reviewed Edited Volume

Frailty and Sarcopenia

Onset, Development and Clinical Challenges

Edited by Yannis Dionyssiotis

National and Kapodistrian University of Athens

Frailty is considered a multisystem impairment that makes an individual vulnerable to external or internal stressors. Sarcopenia, the age-dependent loss of muscle mass and function, is proposed as the biological substrate and the pathway whereby the consequences of physical frailty develop. These syndromes are associated with a negative impact in quality of life and can lead to the occurrence of disability, institutionalization, and even mortality. The book focuses upon all the related aspects of frailty and sarcopenia and the new advancements in the related treatments including complex issues and research. It includes high-quality chapters in all related aspects for the syndromes of sarcopenia and frailty, which adversely affect the function and overall effectiveness of the musculoskeletal system and interventions to promote rehabilitation.

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Frailty and SarcopeniaOnset, Development and Clinical ChallengesEdited by Yannis Dionyssiotis

Published: August 30th 2017

DOI: 10.5772/65153

ISBN: 978-953-51-3484-8

Print ISBN: 978-953-51-3483-1

eBook (PDF) ISBN: 978-953-51-4691-9

Copyright year: 2017

Books open for chapter submissions

16863 Total Chapter Downloads

18 Crossref Citations

16 Web of Science Citations

39 Dimensions Citations


Open access peer-reviewed

1. Epidemiology of Sarcopenia and Frailty

By Harnish P Patel, Esther Clift, Lucy Lewis and Cyrus Cooper


Open access peer-reviewed

2. Sarcopenia in the Context of Skeletal Muscle Function Deficit (SMFD)

By Rosaly Correa-de-Araujo


Open access peer-reviewed

3. From Sarcopenia to Frailty: The Pathophysiological Basis and Potential Target Molecules of Intervention

By Zhuowei Yu, Qingwei Ruan, Grazia D’Onofrio and Antonio Greco


Open access peer-reviewed

4. Sarcopenia and Malnutrition in the Elderly

By Beatriz Lardiés-Sánchez and Alejandro Sanz-París


Open access peer-reviewed

5. Sarcopenic Dysphagia as a New Concept

By Kotomi Sakai and Kunihiro Sakuma


Open access peer-reviewed

6. Rehabilitation in Sarcopenic Elderly

By Raoul Saggini, Simona Maria Carmignano, Lucia Cosenza, Tommaso Palermo and Rosa Grazia Bellomo


Open access peer-reviewed

7. Understanding Cachexia, Sarcopenia, and Physical Exercise in Patients with Cancer

By Shinichiro Morishita, Atsuhiro Tsubaki and Jack B. Fu


Open access peer-reviewed

8. Pancreatic Cancer Cachexia: Current Concepts and Clinical Management

By Michelle Guan, Arvind M. Shinde and Andrew E. Hendifar


Open access peer-reviewed

9. Sarcopenia in Chronic Illness and Rehabilitative Approaches

By Raoul Saggini, Simona Maria Carmignano, Lucia Cosenza, Tommaso Palermo and Rosa Grazia Bellomo


Open access peer-reviewed

10. Frailty and Cardiovascular Disease

By Vinod Chainani, Russell Riehl, Geeta Chainani, Abir Abdo, Mauricio G. Cohen, Carlos Alfonso, Pedro Martinez‐Clark, Carl J. Lavie, John P. Reilly and Nidal Abi‐Rafeh


Open access peer-reviewed

11. Allogeneic Mesenchymal Stem Cells as a Treatment for Aging Frailty

By Bryon A. Tompkins, Ana Marie Landin, Victoria Florea, Makoto Natsumeda, Angela C. Rieger, Wayne Balkan, Ivonne Hernandez Schulman and Joshua M. Hare


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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